Page last updated: 2024-08-17

spironolactone and cimetidine

spironolactone has been researched along with cimetidine in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (33.33)	18.7374
1990's	5 (16.67)	18.2507
2000's	6 (20.00)	29.6817
2010's	9 (30.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Cantabrana, B; Garcia Valencia, V; Gutierrez, M; Hidalgo, A; Sanchez, M	1
Agrawal, JK; Bajpai, HS; Bhatt, RP; Hatwal, A; Singh, G	1
Mowszowicz, I	1
Schmidt, JB	2
Barnes, S; Glass, AR; Hennessey, JV; Vigersky, RA	1
Morris, DV	1
Buchanan, JF; Davis, LJ	1
Braithwaite, SS; Jabamoni, R	1
Costa, C; De Pedrini, P; Suraci, C	1
Raj, SG; Talbert, LM	1
Coney, P	1
Flynn, G; Lieb, LM; Weiner, N	1
Capron, MH; Lauga, J	1
Shaw, JC	1
Getachew, H; Shibeshi, W; Tadesse, Y	1

Reviews

7 review(s) available for spironolactone and cimetidine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Antiandrogens. Mechanisms and paradoxical effects]. Annales d'endocrinologie, 1989, Volume: 50, Issue:3 Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgens; Anilides; Cimetidine; Cyproterone; Cyproterone Acetate; Flutamide; Humans; Nitriles; Spironolactone; Tosyl Compounds	1989
Hirsutism. Clinics in obstetrics and gynaecology, 1985, Volume: 12, Issue:3 Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Androgens; Cimetidine; Cyproterone; Female; Hair; Hair Removal; Hirsutism; Humans; Polycystic Ovary Syndrome; Spironolactone; Ultrasonography	1985
Hirsutism. Archives of dermatology, 1983, Volume: 119, Issue:4 Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Androgen Antagonists; Androgens; Cimetidine; Dehydroepiandrosterone; Female; Hirsutism; Humans; Ovarian Neoplasms; Spironolactone; Testosterone	1983
Polycystic ovarian disease. Obstetrics and gynecology annual, 1984, Volume: 13 Topics: Adrenal Hyperplasia, Congenital; Androgens; Chorionic Gonadotropin; Cimetidine; Clomiphene; Contraceptive Agents, Female; Contraceptive Agents, Male; Cyproterone; Cyproterone Acetate; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Medroxyprogesterone; Medroxyprogesterone Acetate; Ovary; Ovulation Induction; Polycystic Ovary Syndrome; Spironolactone	1984
Polycystic ovarian disease: current concepts of pathophysiology and therapy. Fertility and sterility, 1984, Volume: 42, Issue:5 Topics: 17-Ketosteroids; Adrenal Cortex; Adrenal Glands; Androgen Antagonists; Androstenedione; Animals; Cimetidine; Cyproterone; Cyproterone Acetate; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Humans; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Ovary; Ovulation Induction; Polycystic Ovary Syndrome; Spironolactone; Testosterone	1984
Antiandrogen therapy in dermatology. International journal of dermatology, 1996, Volume: 35, Issue:11 Topics: Adrenal Cortex Hormones; Androgen Antagonists; Cimetidine; Contraceptives, Oral; Cyproterone Acetate; Finasteride; Flutamide; Humans; Ketoconazole; Skin Diseases; Spironolactone	1996

Trials

1 trial(s) available for spironolactone and cimetidine

Article	Year
Spironolactone and cimetidine in treatment of acne. Acta dermato-venereologica, 1988, Volume: 68, Issue:1 Topics: Acne Vulgaris; Adolescent; Adult; Cimetidine; Female; Humans; Male; Random Allocation; Spironolactone	1988

Other Studies

22 other study(ies) available for spironolactone and cimetidine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs	2013
Effects of steroidal and non-steroidal antiandrogens on the left atrium of the rat in vitro. General pharmacology, 1991, Volume: 22, Issue:6 Topics: Androgen Antagonists; Animals; Calcium; Chlormadinone Acetate; Cimetidine; Cyproterone; Electric Stimulation; Female; Flutamide; Heart; Heart Atria; In Vitro Techniques; Male; Medroxyprogesterone; Myocardial Contraction; Rats; Rats, Inbred Strains; Spironolactone; Steroids; Stimulation, Chemical	1991
[The concept of the causal therapy of hirsutism]. Zeitschrift fur Hautkrankheiten, 1986, Feb-15, Volume: 61, Issue:4 Topics: Cimetidine; Cyproterone; Cyproterone Acetate; Hirsutism; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Receptors, Androgen; Spironolactone	1986
Comparative antiandrogenic potency of spironolactone and cimetidine: assessment by the chicken cockscomb topical bioassay. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 182, Issue:4 Topics: Administration, Topical; Androgen Antagonists; Animals; Biological Assay; Chickens; Cimetidine; Comb and Wattles; Dose-Response Relationship, Drug; Male; Organ Size; Spironolactone	1986
Drug-induced infertility. Drug intelligence & clinical pharmacy, 1984, Volume: 18, Issue:2 Topics: Adolescent; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Antipsychotic Agents; Cannabis; Child; Child, Preschool; Cimetidine; Colchicine; Contraceptives, Oral; Female; Humans; Infertility; Male; Middle Aged; Narcotics; Spironolactone; Steroids; Thyroid Hormones	1984
[Therapy of female hirsutism: current status and new findings]. La Clinica terapeutica, 1983, Mar-31, Volume: 104, Issue:6 Topics: Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Androgen Antagonists; Androgens; Bromocriptine; Cimetidine; Cyproterone; Cyproterone Acetate; Drug Combinations; Estradiol Congeners; Female; Hirsutism; Humans; Polycystic Ovary Syndrome; Progesterone Congeners; Spironolactone; Thyronines; Time Factors	1983
Follicular (pilosebaceous unit) deposition and pharmacological behavior of cimetidine as a function of formulation. Pharmaceutical research, 1994, Volume: 11, Issue:10 Topics: Androgen Antagonists; Animals; Cimetidine; Cricetinae; Drug Carriers; Ear, External; In Vitro Techniques; Liposomes; Male; Mesocricetus; Progesterone; Sebaceous Glands; Solutions; Spironolactone	1994
[Breast cancer in the male]. Presse medicale (Paris, France : 1983), 1993, Nov-20, Volume: 22, Issue:36 Topics: Breast Neoplasms; Cimetidine; Digitalis Glycosides; Humans; Isoniazid; Male; Risk Factors; Sex Factors; Spironolactone	1993
Other antiandrogens. Dermatology (Basel, Switzerland), 1998, Volume: 196, Issue:1 Topics: Acne Vulgaris; Androgen Antagonists; Cimetidine; Female; Finasteride; Flutamide; Humans; Isotretinoin; Male; Spironolactone	1998
Drug dosage adjustment in hospitalized patients with renal impairment at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia. BMC nephrology, 2015, Oct-07, Volume: 16 Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Anti-Ulcer Agents; Antifungal Agents; Antihypertensive Agents; Ceftazidime; Cimetidine; Creatinine; Cross-Sectional Studies; Digoxin; Diuretics; Drug Dosage Calculations; Drug Prescriptions; Enalapril; Ethiopia; Female; Fluconazole; Gout Suppressants; Hospitalization; Humans; Male; Medication Errors; Middle Aged; Pharmaceutical Preparations; Prospective Studies; Renal Insufficiency, Chronic; Severity of Illness Index; Spironolactone; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin; Young Adult	2015