Page last updated: 2024-08-17

spironolactone and carbenoxolone sodium

spironolactone has been researched along with carbenoxolone sodium in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (35.00)	18.7374
1990's	7 (35.00)	18.2507
2000's	4 (20.00)	29.6817
2010's	2 (10.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Cross, S; Hole, D; Rees, WD; Rhodes, J	1
Edmonds, CJ	1
Edmonds, CJ; Tomkins, AM	1
Lindup, WE; Parke, DV; Shillingford, JS; Smith, MJ	1
Gomez-Sanchez, CE; Gomez-Sanchez, EP	1
Morris, DJ; Souness, GW	2
Funder, JW; Myles, K; Pearce, PT; Roy, LP	1
Baumgarten, IM; Davidson, JS; Harley, EH	1
Adam, WR; Armanini, D; Funder, JW; Karbowiak, I; Krozowski, Z	1
Edwards, CR; Sang, KS; Walker, BR; Williams, BC	1
Khoo, K; Krozowski, ZS; Li, KX; Sheppard, KE	1
Fadzilah, S; Hamid, A; Khalid, BA; Morat, PB; Nwe, KH	1
Davies, SN; Gwyn, P; Ross, FM; Spanswick, D	1
Dilley, R; Funder, JW; Moussa, L; Young, MJ	1
Dong, Q; Ge, RS; Hardy, MP; Latif, SA; Morris, DJ; Sottas, CM	1
Chepkova, AN; Haas, HL; Sergeeva, OA	1

Reviews

1 review(s) available for spironolactone and carbenoxolone sodium

Article	Year
Electrical potential difference of colonic mucosa. Gut, 1975, Volume: 16, Issue:4 Topics: Aldosterone; Biological Transport, Active; Carbenoxolone; Colitis; Colon; Dinitrophenols; Electrodes; Electrophysiology; Epithelium; Humans; Intestinal Mucosa; Ouabain; Proctitis; Sodium; Spironolactone	1975

Trials

1 trial(s) available for spironolactone and carbenoxolone sodium

Article	Year
Carbenoxolone sodium for gastric ulcer. The Medical letter on drugs and therapeutics, 1975, Aug-01, Volume: 17, Issue:16 Topics: Benzothiadiazines; Body Weight; Carbenoxolone; Clinical Trials as Topic; Diuretics; Duodenal Ulcer; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Sodium Chloride Symporter Inhibitors; Spironolactone; Stomach Ulcer; Triterpenes	1975

Other Studies

18 other study(ies) available for spironolactone and carbenoxolone sodium

Article	Year
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
The effect of an aldosterone antagonist on the protective action of carbenoxolone on the gastric mucosal barrier. The Journal of pharmacy and pharmacology, 1975, Volume: 27, Issue:12 Topics: Animals; Bile; Carbenoxolone; Dogs; Gastric Mucosa; Hydrogen-Ion Concentration; Mineralocorticoid Receptor Antagonists; Sodium; Spironolactone; Stomach; Time Factors; Triterpenes	1975
Electrical potential difference, sodium absorption and potassium secretion by the human rectum during carbenoxolone therapy. Gut, 1975, Volume: 16, Issue:4 Topics: Adult; Aged; Amiloride; Bendroflumethiazide; Carbenoxolone; Dialysis; Electrophysiology; Humans; Hydrocortisone; Intestinal Absorption; Intestinal Mucosa; Middle Aged; Peptic Ulcer; Potassium; Rectum; Sodium; Spironolactone; Triterpenes	1975
Proceedings: The effects of ulcerogenic and ulcer-healing drugs on gastric mucus. Gut, 1975, Volume: 16, Issue:5 Topics: Animals; Carbenoxolone; Gastric Mucins; Gastric Mucosa; Glycoproteins; Humans; Indomethacin; Phenylbutazone; Rats; Spironolactone; Triterpenes	1975
Central hypertensinogenic effects of glycyrrhizic acid and carbenoxolone. The American journal of physiology, 1992, Volume: 263, Issue:6 Topics: Administration, Oral; Animals; Blood Pressure; Brain; Carbenoxolone; Corticosterone; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Spironolactone	1992
The "mineralocorticoid-like" actions conferred on corticosterone by carbenoxolone are inhibited by the mineralocorticoid receptor (type I) antagonist RU28318. Endocrinology, 1991, Volume: 129, Issue:5 Topics: Adrenalectomy; Aldosterone; Animals; Carbenoxolone; Corticosterone; Creatinine; Desoxycorticosterone; Male; Mineralocorticoids; Natriuresis; Potassium; Rats; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone	1991
Apparent mineralocorticoid excess, pseudohypoaldosteronism, and urinary electrolyte excretion: toward a redefinition of mineralocorticoid action. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1990, Volume: 4, Issue:14 Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenalectomy; Aldosterone; Androstanols; Animals; Bicarbonates; Carbenoxolone; Child; Electrolytes; Female; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Male; Mifepristone; Mineralocorticoids; Natriuresis; Pseudohypoaldosteronism; Rats; Rats, Inbred Strains; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone	1990
Reversible inhibition of intercellular junctional communication by glycyrrhetinic acid. Biochemical and biophysical research communications, 1986, Jan-14, Volume: 134, Issue:1 Topics: Carbenoxolone; Cell Communication; Cell Line; Citrulline; Dose-Response Relationship, Drug; Glycyrrhetinic Acid; Humans; Intercellular Junctions; Spironolactone; Tetradecanoylphorbol Acetate	1986
The mechanism of mineralocorticoid action of carbenoxolone. Endocrinology, 1982, Volume: 111, Issue:5 Topics: Adrenalectomy; Aldosterone; Animals; Carbenoxolone; Drug Interactions; Female; Glycyrrhetinic Acid; Kidney; Mineralocorticoids; Potassium; Rats; Rats, Inbred Strains; Receptors, Mineralocorticoid; Receptors, Steroid; Sodium; Spironolactone	1982
Direct and indirect effects of carbenoxolone on responses to glucocorticoids and noradrenaline in rat aorta. Journal of hypertension, 1994, Volume: 12, Issue:1 Topics: Adrenalectomy; Animals; Aorta; Carbenoxolone; Corticosterone; Glucocorticoids; In Vitro Techniques; Male; Mifepristone; Norepinephrine; Rats; Rats, Wistar; Spironolactone; Vasoconstriction	1994
11-Dehydrocorticosterone in the presence of carbenoxolone is a more potent sodium retainer than corticosterone. Steroids, 1993, Volume: 58, Issue:1 Topics: Adrenalectomy; Animals; Carbenoxolone; Corticosterone; Creatinine; Male; Mineralocorticoid Receptor Antagonists; Natriuresis; Potassium; Rats; Rats, Sprague-Dawley; Spironolactone	1993
Steroid specificity of the putative DHB receptor: evidence that the receptor is not 11betaHSD. The American journal of physiology, 1998, Volume: 275, Issue:1 Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carbenoxolone; Cell Nucleus; Cells, Cultured; CHO Cells; Colon; Corticosterone; Cricetinae; Culture Media, Conditioned; Hydroxysteroid Dehydrogenases; Intestinal Mucosa; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Spironolactone; Substrate Specificity; Transfection	1998
Novel effects of deoxycorticosterone on testicular 11beta-hydroxysteroid dehydrogenase activity and plasma testosterone levels in normal and adrenalectomized rats. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 1999, Volume: 107, Issue:5 Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenalectomy; Animals; Carbenoxolone; Desoxycorticosterone; Hydroxysteroid Dehydrogenases; Male; Progesterone; Rats; Rats, Wistar; Reference Values; Spironolactone; Testis; Testosterone	1999
Carbenoxolone depresses spontaneous epileptiform activity in the CA1 region of rat hippocampal slices. Neuroscience, 2000, Volume: 100, Issue:4 Topics: Animals; Carbenoxolone; Depression, Chemical; Epilepsy; Female; Gap Junctions; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; Mineralocorticoid Receptor Antagonists; Octanols; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Spironolactone; Synaptic Transmission	2000
Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: effects of 11 beta-hydroxysteroid dehydrogenase inactivation. Endocrinology, 2003, Volume: 144, Issue:3 Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Blood Pressure; Carbenoxolone; Cardiomegaly; Coronary Disease; Desoxycorticosterone; Enzyme Inhibitors; Eplerenone; Fibrosis; Heart; Hydroxysteroid Dehydrogenases; Kidney; Male; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Myocardium; Nephrectomy; Organ Size; Rats; Rats, Sprague-Dawley; Sodium Chloride; Solutions; Spironolactone; Vasculitis	2003
Stimulation of testosterone production in rat Leydig cells by aldosterone is mineralocorticoid receptor mediated. Molecular and cellular endocrinology, 2005, Nov-24, Volume: 243, Issue:1-2 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Binding Sites; Carbenoxolone; Corticosterone; Drug Synergism; In Vitro Techniques; Leydig Cells; Male; Mineralocorticoid Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Testosterone	2005
Carbenoxolone impairs LTP and blocks NMDA receptors in murine hippocampus. Neuropharmacology, 2008, Volume: 55, Issue:2 Topics: Adrenal Cortex Hormones; Animals; Calcium Channel Blockers; Carbenoxolone; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Hormone Antagonists; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mifepristone; Receptors, N-Methyl-D-Aspartate; Spironolactone; Taurine	2008