Page last updated: 2024-08-17

spironolactone and caffeine

spironolactone has been researched along with caffeine in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (6.67)	18.2507
2000's	5 (33.33)	29.6817
2010's	9 (60.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Baron, A; Loirand, G; Mironneau, C; Mironneau, J; Pacaud, P	1
Bassani, JW; Costa, AR; Ferreira, AT; França, JP; Medei, E; Nascimento, JH; Oshiro, ME; Ricardo, RA; Smaili, S; Torres, LB; Tucci, PJ	1
Charcosset, C; Fessi, H; Jaafar-Maalej, C; Pham, TT	1
Bilos, A; Deinum, J; Donders, AR; Riksen, NP; Rongen, GA; van den Berg, TN	1
Alarie, H; Leclair, G; Roullin, VG	1

Reviews

1 review(s) available for spironolactone and caffeine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for spironolactone and caffeine

Article	Year
The effect of eplerenone on adenosine formation in humans in vivo: a double-blinded randomised controlled study. PloS one, 2014, Volume: 9, Issue:10 Topics: Adenosine; Caffeine; Dipyridamole; Double-Blind Method; Eplerenone; Forearm; Hemodynamics; Humans; Hyperemia; Male; Nitroprusside; Regional Blood Flow; Spironolactone; Treatment Outcome; Young Adult	2014

Other Studies

13 other study(ies) available for spironolactone and caffeine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Pharmacological block of Ca(2+)-activated Cl- current in rat vascular smooth muscle cells in short-term primary culture. Pflugers Archiv : European journal of physiology, 1991, Volume: 419, Issue:6 Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anthracenes; Caffeine; Calcium; Cells, Cultured; Chloride Channels; Chlorides; Membrane Proteins; Muscle, Smooth, Vascular; Rats; Spironolactone	1991
The negative inotropic action of canrenone is mediated by L-type calcium current blockade and reduced intracellular calcium transients. British journal of pharmacology, 2009, Volume: 158, Issue:2 Topics: Animals; Caffeine; Calcium; Calcium Channels, L-Type; Canrenone; Dose-Response Relationship, Drug; Homeostasis; Male; Mineralocorticoid Receptor Antagonists; Myocardial Contraction; Myocytes, Cardiac; Papillary Muscles; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Spironolactone	2009
Liposome and niosome preparation using a membrane contactor for scale-up. Colloids and surfaces. B, Biointerfaces, 2012, Jun-01, Volume: 94 Topics: Caffeine; Drug Compounding; Drug Delivery Systems; Humans; Hydrophobic and Hydrophilic Interactions; Infusion Pumps; Kinetics; Liposomes; Microscopy, Electron, Transmission; Nanospheres; Particle Size; Reproducibility of Results; Spironolactone	2012
Development of a safe and versatile suspension vehicle for pediatric use: Formulation development. International journal of pharmaceutics, 2019, Oct-05, Volume: 569 Topics: Administration, Oral; Caffeine; Drug Compounding; Excipients; Hydrocortisone; Pediatrics; Spironolactone; Suspensions; Tacrolimus; Viscosity	2019