Page last updated: 2024-08-17

spironolactone and bumetanide

spironolactone has been researched along with bumetanide in 21 studies

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (28.57)	18.7374
1990's	2 (9.52)	18.2507
2000's	5 (23.81)	29.6817
2010's	8 (38.10)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Atherton, JC; Green, R; Higgins, A; Large, A; McNicholas, C; Parker, D; Pempkowiak, L; Rajani, K; Smith, J	1
Basile, AS; Lueddens, HW; Skolnick, P	1
Broor, SL; Mishra, SP; Sachdev, G; Sarin, SK; Shrivastwa, A; Sundaram, KR; Talukdar, V	1
Beermann, B	1
Boyer, TD; Warnock, DG	1
Davies, IB; Lightman, SL	1
Alexander, F	1
Donker, AJ; Nauta, JJ; van Vliet, AA; Verheugt, FW	1
Cobbs, S; Jiang, G; Klein, JD; O'Neill, WC	1
Dupont, M; Mullens, W; Nijst, P; Penders, J; Tang, WH; Verbrugge, FH	1
Gravenstein, N; Martynyuk, AE; Seubert, CN; Sumners, C; Tan, S; Vasilopoulos, T; Xu, C; Zhang, J	1
Gravenstein, N; Martynyuk, AE; Puentes, DL; Seubert, CN; Xu, C; Zhang, J	1

Reviews

3 review(s) available for spironolactone and bumetanide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Aspects on pharmacokinetics of some diuretics. Acta pharmacologica et toxicologica, 1984, Volume: 54 Suppl 1 Topics: Amiloride; Bendroflumethiazide; Bumetanide; Chlorthalidone; Diuretics; Furosemide; Humans; Hydrochlorothiazide; Kinetics; Sodium Chloride Symporter Inhibitors; Spironolactone	1984
Refractory oedema. British journal of hospital medicine, 1980, Volume: 23, Issue:3 Topics: Aminophylline; Bumetanide; Diuretics; Drug Therapy, Combination; Edema; Edema, Cardiac; Ethacrynic Acid; Female; Furosemide; Humans; Liver Cirrhosis; Lymphedema; Nephrotic Syndrome; Protein Deficiency; Renal Dialysis; Spironolactone	1980

Trials

2 trial(s) available for spironolactone and bumetanide

Article	Year
Bumetanide, spironolactone and a combination of the two, in the treatment of ascites due to liver disease. A prospective, controlled, randomized trial. Digestion, 1988, Volume: 41, Issue:2 Topics: Administration, Oral; Adult; Ascites; Bumetanide; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Combinations; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Potassium; Prospective Studies; Random Allocation; Sodium; Spironolactone	1988
Use of diuretics in the treatment of cirrhotic ascites. Gastroenterology, 1983, Volume: 84, Issue:5 Pt 1 Topics: Ascites; Bumetanide; Diuresis; Diuretics; Dose-Response Relationship, Drug; Furosemide; Humans; Kidney; Liver Cirrhosis; Natriuresis; Sodium; Spironolactone; Sulfonamides	1983

Article

Year

Bumetanide, spironolactone and a combination of the two, in the treatment of ascites due to liver disease. A prospective, controlled, randomized trial.

Digestion, 1988, Volume: 41, Issue:2

Topics: Administration, Oral; Adult; Ascites; Bumetanide; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Combinations; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Potassium; Prospective Studies; Random Allocation; Sodium; Spironolactone

1988

Use of diuretics in the treatment of cirrhotic ascites.

Gastroenterology, 1983, Volume: 84, Issue:5 Pt 1

Topics: Ascites; Bumetanide; Diuresis; Diuretics; Dose-Response Relationship, Drug; Furosemide; Humans; Kidney; Liver Cirrhosis; Natriuresis; Sodium; Spironolactone; Sulfonamides

1983

Other Studies

16 other study(ies) available for spironolactone and bumetanide

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Lithium clearance in healthy humans: effects of sodium intake and diuretics. Kidney international. Supplement, 1990, Volume: 28 Topics: Amiloride; Benzothiadiazines; Bumetanide; Diuretics; Furosemide; Humans; Lithium; Metabolic Clearance Rate; Reference Values; Sodium Chloride Symporter Inhibitors; Sodium, Dietary; Spironolactone	1990
Regulation of renal peripheral benzodiazepine receptors by anion transport inhibitors. Life sciences, 1988, Volume: 42, Issue:6 Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetazolamide; Amiloride; Animals; Anions; Anthracenes; Biological Transport; Bumetanide; Furosemide; Hydrochlorothiazide; Kidney; Kinetics; Male; Myocardium; Ouabain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spironolactone	1988
The effect of ethacrynic acid, bumetanide, frusemide, spironolactone and ADH on electrolyte excretion in ponies. Journal of veterinary pharmacology and therapeutics, 1982, Volume: 5, Issue:3 Topics: Animals; Body Water; Bumetanide; Chlorides; Diuretics; Electrolytes; Ethacrynic Acid; Furosemide; Horses; Male; Potassium; Sodium; Spironolactone; Vasopressins	1982
Spironolactone in congestive heart failure refractory to high-dose loop diuretic and low-dose angiotensin-converting enzyme inhibitor. The American journal of cardiology, 1993, Jan-21, Volume: 71, Issue:3 Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Bumetanide; Drug Resistance; Drug Therapy, Combination; Female; Heart Failure; Humans; Male; Middle Aged; Renin-Angiotensin System; Spironolactone; Water-Electrolyte Balance	1993
Aldosterone regulates the Na-K-2Cl cotransporter in vascular smooth muscle. Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:5 Topics: Adrenalectomy; Aldosterone; Animals; Aorta; Bumetanide; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rubidium Radioisotopes; Sodium-Potassium-Chloride Symporters; Spironolactone; Time Factors; Vasoconstrictor Agents	2003
Urinary composition during decongestive treatment in heart failure with reduced ejection fraction. Circulation. Heart failure, 2014, Volume: 7, Issue:5 Topics: Administration, Oral; Aged; Biomarkers; Bumetanide; Chlorides; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Echocardiography; Female; Heart Failure; Heart Ventricles; Humans; Injections, Intravenous; Male; Sodium; Spironolactone; Stroke Volume; Treatment Outcome; Urinalysis; Urination; Vasodilator Agents	2014
Anesthesia with sevoflurane in neonatal rats: Developmental neuroendocrine abnormalities and alleviating effects of the corticosteroid and Cl(-) importer antagonists. Psychoneuroendocrinology, 2015, Volume: 60 Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Animals, Newborn; Anxiety; Bumetanide; CA1 Region, Hippocampal; Chloride Channels; Corticosterone; Excitatory Postsynaptic Potentials; Female; Male; Maternal Deprivation; Methyl Ethers; Neurosecretory Systems; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reflex, Startle; Sevoflurane; Sex Characteristics; Spironolactone	2015
Role of Steroids in Hyperexcitatory Adverse and Anesthetic Effects of Sevoflurane in Neonatal Rats. Neuroendocrinology, 2016, Volume: 103, Issue:5 Topics: Anesthetics; Animals; Animals, Newborn; Brain Waves; Bumetanide; Drug Interactions; Estradiol; Estrogen Receptor Antagonists; Female; Fulvestrant; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Methyl Ethers; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex, Righting; Sevoflurane; Sodium Potassium Chloride Symporter Inhibitors; Spironolactone; Steroids	2016