spironolactone has been researched along with arginine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (17.65) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bartter, FC; Golde, DW; Roth, JA; Simopoulos, AP | 1 |
| Ilinich, VK; Plastun, FF | 1 |
| GIRARD, M | 1 |
| Hur, JK; Kim, JB; Lee, KY | 1 |
| Fagart, J; Fay, MR; Huyet, J; Pinon, GM; Rafestin-Oblin, ME | 1 |
| Adamcová, M; Krajcírovicová, K; Matúsková, J; Paulis, L; Pechánová, O; Pelouch, V; Potácová, A; Simko, F | 1 |
| Kunes, J; L'upták, I; Matúsková, J; Pechánová, O; Simko, F; Török, J; Zicha, J | 1 |
| Adamcova, M; Hulin, I; Janega, P; Krajcirovicova, K; Matuskova, J; Paulis, L; Pechanova, O; Pelouch, V; Potacova, A; Simko, F; Simko, J | 1 |
| Kil, TH; Kim, JB | 1 |
| Deng, CN; Shen, LH; Tang, CS | 1 |
| Fujimura, K; Futatsugi, K; Hasegawa, K; Hayashi, K; Hosoya, K; Itoh, H; Kanda, T; Komatsu, M; Minakuchi, H; Shinozuka, K; Tokuyama, H; Wakino, S; Washida, N; Yoshifuji, A | 1 |
| Angel, A; Chernichovski, T; Grupper, A; Hod, T; Kazan, S; Kliuk-Ben Bassat, O; Naveh, S; Schwartz, IF; Shashar, M; Weinstein, T | 1 |
2 review(s) available for spironolactone and arginine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Treatment of acute hepatic insufficiency (a survey of the literature)].
Topics: Acute Disease; Adenosine Triphosphate; Arginine; Chemical and Drug Induced Liver Injury; Exchange Transfusion, Whole Blood; Folic Acid; Gastrointestinal Hemorrhage; Glutamine; Hepatic Encephalopathy; Humans; Hyperkalemia; Liver; Liver Diseases; Potassium Chloride; Radiation Injuries; Spironolactone; Thiamine Pyrophosphate; Thioctic Acid | 1972 |
1 trial(s) available for spironolactone and arginine
| Article | Year |
|---|---|
Insulin resistance in chronic kidney disease is ameliorated by spironolactone in rats and humans.
Topics: Adipose Tissue; Aged; Aldosterone; Amidohydrolases; Animals; Arginine; Cell Nucleus; Cytochrome P-450 CYP11B2; Female; Glomerular Filtration Rate; Glucose Tolerance Test; Homeostasis; Humans; Immediate-Early Proteins; Insulin Resistance; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Nephrectomy; Oxidative Stress; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Renal Insufficiency, Chronic; Renin; Signal Transduction; Spironolactone | 2015 |
14 other study(ies) available for spironolactone and arginine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Subacute necrotizing encephalomyelopathy with vacuolated cells in the bone marrow.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Aldosterone; Amino Acids; Arginine; Bone Marrow; Bone Marrow Cells; Child, Preschool; Corticosterone; Demyelinating Diseases; Encephalomyelitis; Female; Growth Hormone; Humans; Hydrocortisone; Magnesium; Metyrapone; Spinal Cord; Spironolactone; Vitamin B Complex | 1972 |
[THE TREATMENT OF ALCOHOLIC CIRRHOSIS].
Topics: Adrenal Cortex Hormones; Alcoholism; Arginine; Diet; Diet Therapy; Diuretics; Folic Acid; Glutamates; Humans; Lipotropic Agents; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Liver Extracts; Malates; Pterins; RNA; Spironolactone; Sulfonamides; Vitamin B Complex; Vitamin K | 1963 |
A Korean family of hypokalemic periodic paralysis with mutation in a voltage-gated calcium channel (R1239G).
Topics: Acetazolamide; Adolescent; Arginine; Calcium Channels; Calcium Channels, L-Type; Codon; Exons; Family Health; Female; Glycine; Humans; Hypokalemia; Hypokalemic Periodic Paralysis; Korea; Male; Muscle, Skeletal; Mutation; Pedigree; Protein Structure, Tertiary; Sequence Analysis, DNA; Spironolactone | 2005 |
Structural basis of spirolactone recognition by the mineralocorticoid receptor.
Topics: Amino Acid Substitution; Arginine; Asparagine; Binding Sites; Cell Line; Crystallography, X-Ray; Glycine; Humans; Hydrogen Bonding; Kidney; Ligands; Mineralocorticoid Receptor Antagonists; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Receptors, Mineralocorticoid; Spironolactone; Structure-Activity Relationship; Time Factors; Transcriptional Activation; Transfection | 2007 |
Spontaneous, L-arginine-induced and spironolactone-induced regression of protein remodeling of the left ventricle in L-NAME-induced hypertension.
Topics: Animals; Arginine; Blood Pressure; Collagen; Hypertension; Hypertrophy, Left Ventricular; Male; Mineralocorticoid Receptor Antagonists; Muscle Proteins; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Remission, Spontaneous; Spironolactone; Ventricular Remodeling | 2007 |
Comparison of the effect of simvastatin, spironolactone and L-arginine on endothelial function of aorta in hereditary hypertriglyceridemic rats.
Topics: Acetylcholine; Animals; Aorta; Arginine; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; Male; Mineralocorticoid Receptor Antagonists; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; Rats; Rats, Wistar; Simvastatin; Spironolactone; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2007 |
Regression of left ventricular hypertrophy and aortic remodelling in NO-deficient hypertensive rats: effect of L-arginine and spironolactone.
Topics: Animals; Aorta; Arginine; Fibrosis; Hypertension; Hypertrophy, Left Ventricular; Male; Mineralocorticoid Receptor Antagonists; Models, Animal; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Spironolactone | 2008 |
Severe respiratory phenotype caused by a de novo Arg528Gly mutation in the CACNA1S gene in a patient with hypokalemic periodic paralysis.
Topics: Adolescent; Amiloride; Amino Acid Substitution; Arginine; Calcium Channels; Calcium Channels, L-Type; Cold Temperature; DNA Mutational Analysis; Genotype; Glycine; Humans; Hypokalemic Periodic Paralysis; Male; Mutation; Potassium; Respiratory Insufficiency; Spironolactone | 2010 |
[Effect of spironolactone on L-arginine/iNOS/NO pathway of aortic adventitia in spontaneously hypertensive rats].
Topics: Animals; Aorta; Arginine; Connective Tissue; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spironolactone | 2010 |
Mineralocorticoid receptor blockade improves arginine transport and nitric oxide generation through modulation of cationic amino acid transporter-1 in endothelial cells.
Topics: Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Eplerenone; Glycosylation; Human Umbilical Vein Endothelial Cells; Humans; Mineralocorticoid Receptor Antagonists; Nitric Oxide; Phosphorylation; Protein Kinase C-alpha; Receptors, Mineralocorticoid; Signal Transduction; Spironolactone | 2018 |