spironolactone has been researched along with antipyrine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (66.67) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Fraser, HS; Khan, C; Thompson, D | 1 |
| Hepner, GW; Piken, E | 1 |
| Bass, O; Baur, HR; Masson, JP; Ohnhaus, EE | 1 |
| Challiner, MR; Park, BK; Whittaker, AD | 1 |
| Rawlins, MD; Smith, SE; Taylor, SA | 1 |
| Azarnoff, DL; Huffman, DH; Pentikäinen, P; Shoeman, DW | 1 |
| Kiseleva, ZM; Kuz'mina, AE; Sycheva, IM; Vinogradov, AV | 1 |
| Gerber-Taras, E; Ohnhaus, EE | 1 |
| Frenkl, R; Györe, A; Mészáros, J; Szeberényi, S | 1 |
| Dhumeaux, D; Joanne, C; Miguet, JP; Thebault-Lucas, A; Vuitton, D | 1 |
| Gachályi, B; Renczes, G; Szabó, I | 1 |
| Janus, K; Suszycka, J | 1 |
2 trial(s) available for spironolactone and antipyrine
| Article | Year |
|---|---|
The effect of spironolactone on antipyrine metabolism in man.
Topics: Adult; Antipyrine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Half-Life; Humans; Hydroxylation; Male; Spironolactone; Time Factors | 1973 |
Spironolactone and enzyme induction in patients with alcoholic cirrhosis.
Topics: Adult; Aged; Antipyrine; Body Weight; Drug Interactions; Enzyme Induction; Female; Furosemide; Humans; Liver; Liver Cirrhosis, Alcoholic; Male; Metabolic Clearance Rate; Middle Aged; Spironolactone | 1980 |
13 other study(ies) available for spironolactone and antipyrine
| Article | Year |
|---|---|
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Clinical application of antipyrine half life in saliva in a patient with osteomalacia.
Topics: Aged; Antipyrine; Barbiturates; Enzyme Induction; Female; Half-Life; Humans; Osteomalacia; Spironolactone | 1976 |
Decreased hepatic microsomal reserve in patients with cirrhosis. Studies using aminopyrine as model drug.
Topics: Adult; Aminopyrine; Antipyrine; Female; Humans; Liver Cirrhosis, Alcoholic; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Spironolactone | 1979 |
[The pharmacokinetics of digoxin during chronic spironolacton treatment (author's transl)].
Topics: Adult; Aged; Antipyrine; Digoxin; Feces; Female; Half-Life; Heart Failure; Humans; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Spironolactone | 1978 |
The effect of enzyme induction on the irreversible binding of ethynyloestradiol to guinea pig liver microsomes.
Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Enzyme Induction; Ethinyl Estradiol; Flavonoids; Guinea Pigs; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Rifampin; Spironolactone | 1978 |
Spironolactone--a weak enzyme inducer in man.
Topics: Adult; Antipyrine; Biotransformation; Drug Interactions; Enzyme Induction; Female; Half-Life; Humans; Liver; Male; Phenobarbital; Spironolactone | 1972 |
[Distribution of fluid between the cells and the extracellular media and mineralocorticoid function of the adrenal glands in cardiac insufficiency].
Topics: Adrenal Glands; Adult; Aldosterone; Antipyrine; Body Fluids; Chromatography, Paper; Coronary Disease; Extracellular Space; Female; Heart Failure; Humans; Indicator Dilution Techniques; Male; Methods; Middle Aged; Rheumatic Heart Disease; Spironolactone; Thiosulfates; Water-Electrolyte Balance | 1969 |
The effect of spironolactone on the liver microsomal enzyme system in patients.
Topics: Adult; Aged; Antipyrine; gamma-Glutamyltransferase; Humans; Hydrocortisone; Microsomes, Liver; Middle Aged; Spironolactone | 1984 |
A study of the enzyme inducing effect of physical exercise in man. The "trained liver".
Topics: Adult; Antipyrine; Enzyme Induction; Female; Humans; Microsomes, Liver; Physical Exertion; Spironolactone; Sports Medicine | 1980 |
The effect of combined pre-treatment on the metabolism of antipyrine in the rat.
Topics: Animals; Antipyrine; Enzyme Activation; Half-Life; Kinetics; Male; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Wistar; Spironolactone | 1995 |
Effect of spironolactone on antipyrine metabolism in calves.
Topics: Animals; Antipyrine; Biotransformation; Cattle; Female; Half-Life; Metabolic Clearance Rate; Spironolactone | 1996 |