spironolactone has been researched along with amiloride in 167 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 89 (53.29) | 18.7374 |
| 1990's | 21 (12.57) | 18.2507 |
| 2000's | 27 (16.17) | 29.6817 |
| 2010's | 29 (17.37) | 24.3611 |
| 2020's | 1 (0.60) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Abignente, F; Aliperta, A; Caldarelli, G; Castagnolo, B; De Colibus, V; Napolitano, L | 1 |
| Fraser, R; Hettiarachchi, J; Morton, JJ; Ramsay, LE; Shelton, J | 1 |
| Eisalo, A; Kohvakka, A; Manninen, V | 1 |
| Berg, KJ | 1 |
| Dirks, JH | 1 |
| Boer, P; Dorhout Mees, EJ; Geyskes, GG; Radó, JP; Simatupang, TA; Vos, J | 1 |
| Beevers, DG; Boddy, K; Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Kremer, D; Lever, AF; Robertson, JI | 1 |
| Alhenc-Gelas, F; Corvol, P; Ducrocq, MB; Menard, J; Plouin, PF | 1 |
| Burkinshaw, L; Davidson, C; Morgan, DB | 1 |
| Hierholzer, K | 1 |
| Benvenuti, C; Sanguigni, D | 1 |
| Corvol, P; Milliez, P; Thibonnier, M | 1 |
| Hall, WD | 1 |
| Esch, I; Gaul, G; Placheta, P | 1 |
| Gussin, RZ | 1 |
| Juhos, E; Radó, JP; Sawinsky, I | 2 |
| Espiner, EA; Hughes, H; Nicholls, MG; Rogers, T | 1 |
| Juhos, E; Radó, JP | 1 |
| Albiez, G; Knauf, H; Lübcke, R; Wais, U | 1 |
| Cuthbert, AW; Shum, WK | 1 |
| Davies, DL; Wilson, GM | 1 |
| Edmonds, CJ; Tomkins, AM | 1 |
| Rowe, WS | 1 |
| Cummings, JR; Gussin, RZ; Ronsberg, MA; Stokey, EH | 1 |
| Vesin, P | 1 |
| Glezer, GA; Lipko, DS | 1 |
| Airaghi, C; Colussi, G; Loli, P; Minetti, L; Rombolà, G; Verde, G | 1 |
| Antillon, MR; McHutchison, JG; Runyon, BA | 1 |
| Levin, RJ; Nzegwu, HC | 1 |
| Hayashi, T; Miyabo, S; Nakai, T | 1 |
| Kairaitis, K; Lumbers, ER | 1 |
| Orlando, R; Sawadogo, A | 1 |
| Atherton, JC; Green, R; Higgins, A; Large, A; McNicholas, C; Parker, D; Pempkowiak, L; Rajani, K; Smith, J | 1 |
| Capek, K; Pácha, J; Popp, M | 3 |
| Giebisch, G; Horisberger, JD | 1 |
| Cragoe, EJ; Kleyman, TR; Kraehenbuhl, JP | 1 |
| Cragoe, EJ; Donoso, VS; Grantham, JA; Grantham, JJ | 1 |
| Bolli, P; Brouwer, RM; Bühler, FR; Conen, D; Erné, P; Kiowski, W | 1 |
| Cox, M; Feldman, GM; Jorkasky, D | 1 |
| Jina, AG; Stone, C; Tormey, WP | 1 |
| Binder, HJ; McGlone, F; Sandle, GI | 1 |
| Basile, AS; Lueddens, HW; Skolnick, P | 1 |
| Moore, MA | 1 |
| Dietl, P; Oberleithner, H; Silbernagl, S; Weigt, M | 1 |
| DuBose, TD; Good, DW | 1 |
| Krishna, GG; Narins, RG; Shulman, MD | 1 |
| Charru, A; Chatellier, G; Corvol, P; Degoulet, P; Jeunemaitre, X; Julien, J; Ménard, J; Plouin, PF | 1 |
| Akbar, FA; Cranfield, FR; Markanday, S; Shelton, JR; Walters, EG | 1 |
| Binder, HJ; Boulpaep, EL; Budinger, ME; Halevy, J; Hayslett, JP | 1 |
| Dyckner, T; Wester, PO | 1 |
| Velázquez, H; Wright, FS | 1 |
| Krzesinski, JM; Rorive, G | 1 |
| Houston, MC; Johnston, PE | 1 |
| Bentley, PJ; Grubb, BR | 1 |
| Chaithiraphan, S; Dhiantravan, Y; Sahasakul, Y | 1 |
| Pockros, PJ; Reynolds, TB | 1 |
| Holland, OB | 1 |
| Lant, A | 1 |
| Nekrasova, AA | 1 |
| Cortright, RN; Groseclose, RG; Hopfer, U; Will, PC | 1 |
| Espiner, EA; Ikram, H; Nicholls, MG; Stewart, DE | 1 |
| Breckenridge, AM; Dollery, CT; George, CF | 1 |
| Beevers, DG; Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Kremer, D; Lever, AF; Robertson, JI | 1 |
| Ilett, KF; Lockett, MF | 1 |
| Brummer, P | 1 |
| Cooper, P | 1 |
| Rorive, GL | 1 |
| Sanna, GP | 1 |
| Leemhuis, MP; Struyvenberg, A | 1 |
| Distler, A | 1 |
| Bernik, V | 1 |
| Brown, JJ; Davies, DL; Fraser, R; Kremer, D; Lever, AF; Robertson, JI | 1 |
| Morgan, TO | 1 |
| Distler, A; Keim, HJ; Philipp, T; Philippi, A; Walter, U; Werner, E | 1 |
| Reubi, FC | 1 |
| Meyer, P; Milliez, P | 1 |
| Savoie, LL | 1 |
| Anderton, JL; Kincaid-Smith, P | 1 |
| Davson, H; Segal, MB | 1 |
| Harinck, HI; Moolenaar, AJ; van Brummelen, P; Van Seters, AP | 1 |
| Kokko, JP; Marver, D; Petty, KJ | 1 |
| Descos, L; Durbec, JP; Fermanian, J; Fombonne, E; Gauthier, A; Levy, VG; Michel, H; Quinton, A; Rueff, B | 1 |
| Beermann, B | 1 |
| Cumming, AM; Fraser, R; Leckie, B; Mason, P; Millar, JA; Robertson, JI | 1 |
| Drayer, JI; Hoefnagels, WH; Kloppenborg, PW; Smals, AG | 1 |
| Coghlan, JP; Scoggins, BA | 1 |
| Carney, S; Morgan, T; Myers, J | 1 |
| McInnes, GT | 1 |
| Holzgreve, H | 1 |
| Herbinger, W | 1 |
| Ceccarelli, S; Charney, AN; Costenbader, CL; Donowitz, M; Wallach, J | 1 |
| Fraser, R; Hettiarachchi, J; Morton, JJ; Ramsay, LE | 1 |
| Hopfer, U; Lebowitz, JL; Will, PC | 1 |
| Clauss, W; Hoffmann, B; Krattenmacher, R; Van Driessche, W | 1 |
| Malchoff, CD; Malchoff, DM; Reardon, G | 1 |
| Gómez Sánchez, EP | 1 |
| Colussi, G; De Ferrari, ME; Macaluso, M; Minetti, L; Rombolà, G | 1 |
| Bonet-Domingo, E; Garcia-Alvarez-Coque, MC; Medina-Hernandez, MJ | 1 |
| Davies, DL; Forrest, G; McInnes, GT; Murdoch, DL | 1 |
| Asano, Y; Kawakami, K; Muto, S; Nagano, K; Nemoto, J; Ohtaka, A; Watanabe, Y; Yamaki, M | 1 |
| Haris, A; Radó, J | 1 |
| Dominiak, P | 1 |
| Hong, JH; Hur, GM; Jeon, JR; Lee, JH; Seok, JH; Sung, JY | 1 |
| Geibel, JP; Harvey, BJ; O'Sullivan, GC; Schneider, MF; Winter, DC | 1 |
| Haris, A; Radó, JP | 1 |
| Bubien, JK; Zhou, ZH | 1 |
| Ambrosius, WT; Eckert, GJ; Newman, S; Pratt, JH | 1 |
| Massien-Simon, C; Plouin, PF | 1 |
| Assadi, FK; Kimura, RE; Patel, S; Subramanian, U | 1 |
| Albermann, L; Hillebrand, U; Ludwig, T; Oberleithner, H; Riethmüller, C; Schäfer, C; Schillers, H; Shahin, V | 1 |
| Schiffrin, EL | 1 |
| Oberleithner, H | 1 |
| Huang, BS; Leenen, FH | 1 |
| Freedman, DB; Housley, D | 1 |
| Ambrosius, WT; Chun, TY; Eckert, GJ; Pratt, JH; Saha, C; Wagner, MA; Zhao, Q | 1 |
| Bell, PD; Warnock, DG | 1 |
| Pratt, JH | 1 |
| Kusano, E; Miyata, Y; Muto, S | 1 |
| Bouloux, PM; Janmohamed, S | 1 |
| Kaşifoğlu, T; Yalçin, AU | 1 |
| Griffon, C; Miternique-Grosse, A; Neuville, A; Siegel, L; Stephan, D; Weltin, D | 1 |
| Ashby, MJ; Brown, MJ; Hood, SJ; Taylor, KP | 1 |
| Bangel, N; Kusche-Vihrog, K; Nechyporuk-Zloy, V; Oberleithner, H; Schillers, H; Schwab, A; Sobczak, K; Wilhelmi, M | 1 |
| Beevers, DG; Lane, DA | 1 |
| Appleton, DS; Brown, MJ; Mir, FA | 1 |
| Hopfer, U; Jose, PA; Pinho, MJ; Pinto, V; Soares-da-Silva, P | 1 |
| Milan, A; Mulatero, P; Veglio, F | 1 |
| Gabor, A; Leenen, FH | 1 |
| Baig, M; Scott, D; Shakur, R | 1 |
| Stowasser, M | 1 |
| Kil, TH; Kim, JB | 1 |
| Amin, MS; El-Shahat, E; Huang, BS; Leenen, FH; Tuana, BS; Wang, HW | 1 |
| Ecker, G; Masilamani, SM; West, C; Zhang, Z | 1 |
| Brownstein, DG; Chapman, K; Deuchar, GA; Hadoke, PWF; Kotelevtsev, YV; McLean, D; Mullins, JJ; Seckl, JR; Webb, DJ | 1 |
| Ahmed, AH; Gordon, RD; Pimenta, E; Stowasser, M; Sukor, N | 1 |
| Cho, E; Cho, M; Gui, SR; Hwang, TH; Kim, JE; Kim, MK; Lee, HJ; Lee, YK; Lee, YS; Rho, J | 1 |
| Gjørup, PH; Larsen, T; Lauridsen, TG; Matthesen, SK; Nielsen, S; Nykjær, KM; Pedersen, EB; Vase, H | 1 |
| Azizi, M; Bobrie, G; Boutouyrie, P; Chatellier, G; Frank, M; Laurent, S; Menard, J; Peyrard, S; Plouin, PF | 1 |
| Jensen, JM; Larsen, T; Lauridsen, TG; Matthesen, SK; Pedersen, EB; Vase, H | 1 |
| Gnudi, L; Karalliedde, J; Manoharan, D; Mohan, V; Parthasarathy, N; Subramani, P; Subramaniyam, G; Sundaramoorthy, C; Viberti, G; Viswanathan, V | 1 |
| Kumagai, H; Nishida, Y; Oda, T; Onimaru, H; Oshima, N; Takechi, H; Uchida, T; Watanabe, A; Yamamoto, K | 1 |
| Bertorello, AM; Grant, R; Hagaman, JR; Hathaway, CM; Hiller, S; Kakoki, M; Kayashima, Y; Kim, HS; Li, F; Mamenko, M; Matsuki, K; Pochynyuk, OM; Smithies, O; Tomita, H; Xu, L; Zaika, OL | 1 |
| MacWalter, RS; McSwiggan, S; Ogston, SA; Struthers, AD; Sze, KY; Wong, KY; Wong, SY | 1 |
| Aliaga, S; Chantala, K; Clark, RH; Herring, AH; Hornik, CP; Hughes, R; Laughon, MM; Smith, PB | 1 |
| Drüppel, V; Kliche, K; Kusche-Vihrog, K; Oberleithner, H; Paar, M; Pavenstädt, H | 1 |
| Carretero, OA; D'Ambrosio, MA; Garvin, JL; Kutskill, K; Leung, P; Peterson, EL; Ren, Y; Wang, H | 1 |
| Azizi, M; Bobrie, G; Chatellier, G; Frank, M; Ménard, J; Perdrix, L; Plouin, PF | 1 |
| Allard, J; Azizi, M; Baron, S; Bergerot, D; Blanchard, A; Bridoux, F; Caumont-Prim, A; Desport, E; Dubourg, L; Essig, M; Monge, M; Tack, I; Vallet, M; Vargas-Poussou, R | 1 |
| Buhl, KB; Gram, J; Hansen, MR; Henriksen, JE; Jacobsen, IA; Jensen, BL; Oxlund, CS; Schousboe, K; Tarnow, L | 1 |
| Chudek, J; Maruniak-Chudek, I; Olszanecka-Glinianowicz, M; Sikora, J; Wyskida, K; Wyskida, M | 1 |
| Ernst, ME; Kostis, JB; Roush, GC; Sica, DA; Yeasmin, S | 1 |
| Brown, MJ; Caulfield, MJ; Cruickshank, JK; Ford, I; MacDonald, TM; Mackenzie, IS; McInnes, GT; Morant, SV; Padmanabhan, S; Salsbury, J; Sever, P; Webb, DJ; Williams, B | 1 |
| Calhoun, DA | 1 |
| Huang, QF; Staessen, JA; Wei, FF; Zhang, ZY | 1 |
| Choy, KW | 1 |
| Hill, MA; Sowers, JR | 1 |
| Baltu, D; Çelik Ertaş, NB; Duzova, A; Gönç, N; Gulhan, B; Ozcan, HN; Özdemir, G; Ünsal, Y; Utine, E | 1 |
23 review(s) available for spironolactone and amiloride
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Diuretics: mechanism of action and clinical application.
Topics: Acute Kidney Injury; Amiloride; Animals; Benzothiadiazines; Diabetes Insipidus; Diuretics; Diuretics, Osmotic; Dogs; Edema; Ethacrynic Acid; Female; Guinea Pigs; Humans; Hypertension, Renal; In Vitro Techniques; Infant, Newborn; Kidney; Male; Mice; Pregnancy; Pregnancy Complications; Rats; Sodium Chloride Symporter Inhibitors; Spironolactone; Sulfonamides; Triamterene | 1975 |
Potassium-sparing diuretics.
Topics: Aldosterone; Amiloride; Animals; Biological Transport; Diuretics; Humans; Ion Channels; Kidney; Potassium; Sodium; Spironolactone; Triamterene | 1987 |
Effects of diuretics on renal acid-base transport.
Topics: Acid-Base Equilibrium; Amiloride; Ammonia; Animals; Benzothiadiazines; Bicarbonates; Carbonic Anhydrase Inhibitors; Diuretics; Furosemide; Humans; Kidney Tubules; Sodium Chloride Symporter Inhibitors; Spironolactone | 1988 |
Clinical use of the potassium-sparing diuretics.
Topics: Amiloride; Humans; Hypertension, Renal; Hypokalemia; Potassium; Spironolactone; Triamterene | 1988 |
Control by drugs of renal potassium handling.
Topics: Acetazolamide; Amiloride; Animals; Diuretics; Furosemide; Humans; Hydrochlorothiazide; Indans; Kidney; Kidney Tubules; Potassium; Spironolactone | 1986 |
[Properties and indications of potassium-sparing diuretics].
Topics: Amiloride; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypokalemia; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene | 1986 |
Essential hypertension: new insights and controversies in treatment with diuretics.
Topics: Amiloride; Antihypertensive Agents; Blood Pressure; Coronary Disease; Diuretics; Dose-Response Relationship, Drug; Drug Combinations; Furosemide; Humans; Hydrochlorothiazide; Hyperkalemia; Hypertension; Lipoproteins, LDL; Magnesium; Potassium; Potassium Chloride; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene; Triglycerides | 1986 |
Diuretics. Clinical pharmacology and therapeutic use (Part II).
Topics: Amiloride; Canrenoic Acid; Diuretics; Diuretics, Osmotic; Drug Interactions; Hearing Disorders; Heart Failure; Humans; Hypertension; Hypokalemia; Indans; Kidney Failure, Chronic; Liver Diseases; Potassium; Pulmonary Edema; Spironolactone; Ticrynafen; Triamterene; Uricosuric Agents; Water-Electrolyte Imbalance; Xanthines | 1985 |
Significance of hypokalaemia due to diuretics.
Topics: Amiloride; Arrhythmias, Cardiac; Chlorothiazide; Diuretics; Ethacrynic Acid; Extracellular Space; Furosemide; Hepatic Encephalopathy; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Kidney Tubules; Liver Cirrhosis; Natriuresis; Potassium; Potassium Chloride; Spironolactone; Triamterene | 1973 |
[The problem of potassium and diuretics].
Topics: Administration, Oral; Amiloride; Benzothiadiazines; Clopamide; Digitalis Glycosides; Diuretics; Drug Evaluation; Heart Failure; Humans; Potassium; Potassium Deficiency; Spironolactone; Triamterene; Water-Electrolyte Balance | 1972 |
Combination diuretic drug therapy.
Topics: Amiloride; Benzothiadiazines; Diet; Diuretics; Drug Therapy, Combination; Ethacrynic Acid; Furosemide; Glomerular Filtration Rate; Heart Failure; Humans; Hyperaldosteronism; Hyperglycemia; Hyperkalemia; Hypokalemia; Hyponatremia; Hypoproteinemia; Kidney; Liver Diseases; Nephrotic Syndrome; Organomercury Compounds; Regional Blood Flow; Sodium Chloride; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene | 1971 |
Aspects on pharmacokinetics of some diuretics.
Topics: Amiloride; Bendroflumethiazide; Bumetanide; Chlorthalidone; Diuretics; Furosemide; Humans; Hydrochlorothiazide; Kinetics; Sodium Chloride Symporter Inhibitors; Spironolactone | 1984 |
Primary hyperaldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Amiloride; Diagnosis, Differential; Female; Glucocorticoids; Hemodynamics; Humans; Hyperaldosteronism; Hyperplasia; Kidney; Pregnancy; Radionuclide Imaging; Renin; Spironolactone | 1980 |
Sodium and hypertension. A review of the role of sodium in pathogenesis and the action of diuretic drugs.
Topics: Age Factors; Aldosterone; Amiloride; Benzothiadiazines; Diuretics; Furosemide; Humans; Hypertension; Kidney Diseases; Kidney Tubules, Distal; Loop of Henle; Sodium; Sodium Chloride Symporter Inhibitors; Spironolactone | 1980 |
[Potassium-sparing diuretics (spironolactone, triamterene, amylorid)].
Topics: Amiloride; Diuretics; Humans; Hypertension; Hypokalemia; Potassium Deficiency; Spironolactone; Triamterene | 1996 |
[Primary hyperaldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Algorithms; Amiloride; Diagnosis, Differential; Diuretics; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Length of Stay; Magnetic Resonance Imaging; Middle Aged; Mineralocorticoid Receptor Antagonists; Patient Selection; Potassium; Renin; Spironolactone; Time Factors; Tomography, X-Ray Computed | 1998 |
Nuclear envelope: nanoarray responsive to aldosterone.
Topics: Aldosterone; Amiloride; Animals; Cell Membrane; Cell Nucleus; Humans; Macromolecular Substances; Microarray Analysis; Microscopy, Atomic Force; Nuclear Envelope; Nuclear Pore; Sodium Channels; Spironolactone | 2004 |
Improvement in blood pressure with inhibition of the epithelial sodium channel in blacks with hypertension.
Topics: Amiloride; Black People; Blood Pressure; Epithelial Sodium Channels; Humans; Hypertension; Sodium Channel Blockers; Sodium Channels; Spironolactone | 2005 |
The pharmacological treatment of primary aldosteronism.
Topics: Aldosterone; Amiloride; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combination; Glucocorticoids; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Practice Guidelines as Topic; Receptors, Mineralocorticoid; Sodium Channel Blockers; Spironolactone | 2006 |
[Hypertension in the course of primary aldosteronism during pregnancy].
Topics: Acid Sensing Ion Channel Blockers; Aldosterone; Amiloride; Antihypertensive Agents; Eplerenone; Female; Humans; Hyperaldosteronism; Hypertension; Poland; Pregnancy; Pregnancy Complications; Progesterone; Spironolactone | 2015 |
Dose doubling, relative potency, and dose equivalence of potassium-sparing diuretics affecting blood pressure and serum potassium: systematic review and meta-analyses.
Topics: Amiloride; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Eplerenone; Humans; Hyperkalemia; Potassium; Sodium Chloride Symporter Inhibitors; Spironolactone; Therapeutic Equivalency; Triamterene | 2016 |
Diagnosis and management of resistant hypertension: state of the art.
Topics: Amiloride; Animals; Antihypertensive Agents; Arteriovenous Shunt, Surgical; Baroreflex; Blood Pressure Determination; Carotid Arteries; Carotid Body; Coronary Vasospasm; Electric Stimulation Therapy; Epithelial Sodium Channel Blockers; Humans; Hypertension; Medication Adherence; Mineralocorticoid Receptor Antagonists; Pressoreceptors; Renal Artery; Spironolactone; Sympathectomy | 2018 |
24 trial(s) available for spironolactone and amiloride
| Article | Year |
|---|---|
[Clinical evaluation of the use of diuretics in the ascitic phase of hepatic cirrhosis].
Topics: Acute Disease; Adult; Aged; Amiloride; Ascites; Clinical Trials as Topic; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Furosemide; Humans; Hydrochlorothiazide; Liver Cirrhosis; Male; Middle Aged; Spironolactone; Triamterene | 1977 |
The relative potency of amiloride and spironolactone in bendrofluazide-treated hypertensive patients [proceedings].
Topics: Amiloride; Bendroflumethiazide; Clinical Trials as Topic; Humans; Hypertension; Pyrazines; Spironolactone | 1978 |
Maintenance of potassium balance during diuretic therapy.
Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Placebos; Potassium; Potassium Chloride; Pyrazines; Spironolactone; Triamterene | 1979 |
The effects of potassium supplements, spironolactone of amiloride on the potassium status of patients with heart failure.
Topics: Adult; Aged; Amiloride; Female; Furosemide; Heart Failure; Humans; Male; Middle Aged; Potassium; Potassium Deficiency; Pyrazines; Spironolactone | 1978 |
[Plasma renin activity in essential hypertension: different short- und long-term effects of diuretics (author's transl)].
Topics: Adult; Amiloride; Canrenoic Acid; Chlorthalidone; Clinical Trials as Topic; Diuresis; Diuretics; Female; Humans; Hypertension; Long-Term Care; Male; Middle Aged; Renin; Spironolactone; Time Factors | 1976 |
Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Proline; Renin; Renin-Angiotensin System; Spironolactone; Verapamil | 1985 |
A comparative study of Spiroprop and Moducren in the treatment of mild to moderate hypertension in general practice.
Topics: Adolescent; Amiloride; Antihypertensive Agents; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Propranolol; Spironolactone; Timolol | 1988 |
Comparison of the potassium- retaining effects of amiloride and spironolactone in hypertensive patients with thiazide-induced hypokalaemia.
Topics: Adult; Aged; Amiloride; Blood Pressure; Body Weight; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Pyrazines; Sodium; Spironolactone; Time Factors; Urea | 1973 |
[Treatment of the hypertensive patient. Value of Amiloride during saldiuretic treatment].
Topics: Adult; Amiloride; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Kidney Function Tests; Male; Middle Aged; Natriuresis; Potassium; Pyrazines; Spironolactone; Water-Electrolyte Balance | 1972 |
Comparison of six treatments of ascites in patients with liver cirrhosis. A clinical trial.
Topics: Amiloride; Ascites; Blood Chemical Analysis; Clinical Trials as Topic; Diet, Sodium-Restricted; Diuretics; Drainage; Drug Combinations; Furosemide; Humans; Hydrochlorothiazide; Liver Cirrhosis; Random Allocation; Spironolactone | 1983 |
A comparison of the potassium and magnesium-sparing properties of amiloride and spironolactone in diuretic-treated normal subjects.
Topics: Adult; Aldosterone; Amiloride; Double-Blind Method; Drug Interactions; Erythrocytes; Humans; Hydrochlorothiazide; Intracellular Fluid; Magnesium; Male; Potassium; Spironolactone | 1993 |
Patterns of potassium wasting in response to stepwise combinations of diuretics in nephrotic syndrome.
Topics: Aged; Amiloride; Body Weight; Chlorthalidone; Diuresis; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Male; Middle Aged; Nephrotic Syndrome; Potassium; Regression Analysis; Sodium; Spironolactone; Triamterene | 1999 |
Blood pressure responses to small doses of amiloride and spironolactone in normotensive subjects.
Topics: Adult; Amiloride; Blood Pressure; Drug Synergism; Epithelial Sodium Channels; Female; Humans; Male; Mineralocorticoid Receptor Antagonists; Sodium Channel Blockers; Sodium Channels; Spironolactone | 2001 |
Central role for ENaC in development of hypertension.
Topics: Aldosterone; Amiloride; Antihypertensive Agents; Blood Pressure; Epithelial Sodium Channels; Humans; Hypertension; Risk Factors; Sodium; Sodium Channels; Spironolactone; Urothelium | 2005 |
The effects of thiazide and thiazide-potassium sparing diuretics on fibrinolytic system parameters.
Topics: Amiloride; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Female; Fibrinolysis; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Plasminogen Activator Inhibitor 1; Spironolactone; Tissue Plasminogen Activator; Treatment Outcome | 2006 |
The spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio.
Topics: Aged; Aldosterone; Amiloride; Bendroflumethiazide; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Renin; Single-Blind Method; Sodium Chloride Symporter Inhibitors; Spironolactone | 2007 |
Effect of amiloride and spironolactone on renal tubular function, ambulatory blood pressure, and pulse wave velocity in healthy participants in a double-blinded, randomized, placebo-controlled, crossover trial.
Topics: Adolescent; Adult; Algorithms; Amiloride; Aquaporin 2; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Diuretics; Double-Blind Method; Epithelial Sodium Channels; Female; Glomerular Filtration Rate; Humans; Kidney Tubules; Male; Pulse Wave Analysis; Renin-Angiotensin System; Spironolactone | 2012 |
Sequential nephron blockade versus sequential renin-angiotensin system blockade in resistant hypertension: a prospective, randomized, open blinded endpoint study.
Topics: Adolescent; Adult; Aged; Amiloride; Angiotensin-Converting Enzyme Inhibitors; Biological Transport; Bisoprolol; Blood Pressure; Drug Resistance; Drug Therapy, Combination; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Nephrons; Prospective Studies; Ramipril; Renin-Angiotensin System; Spironolactone; Young Adult | 2012 |
Effect of amiloride and spironolactone on renal tubular function and central blood pressure in patients with arterial hypertension during baseline conditions and after furosemide: a double-blinded, randomized, placebo-controlled crossover trial.
Topics: Aged; Aldosterone; Amiloride; Angiotensin II; Aquaporin 2; Blood Pressure; Cross-Over Studies; Diuretics; Double-Blind Method; Epithelial Sodium Channels; Female; Furosemide; Humans; Hypertension; Kidney Tubules; Male; Middle Aged; Potassium; Pulse Wave Analysis; Renin; Sodium; Spironolactone | 2013 |
Effect of spironolactone and amiloride on thiazolidinedione-induced fluid retention in South Indian patients with type 2 diabetes.
Topics: Adult; Aged; Amiloride; Diabetes Mellitus, Type 2; Diuretics; Edema; Female; Humans; Male; Middle Aged; Rosiglitazone; Spironolactone; Thiazolidinediones | 2013 |
Myocardial fibrosis and QTc are reduced following treatment with spironolactone or amiloride in stroke survivors: a randomised placebo-controlled cross-over trial.
Topics: Aged; Amiloride; Cross-Over Studies; Diuretics; Double-Blind Method; Female; Fibrosis; Heart Diseases; Humans; Hypertrophy, Left Ventricular; Long QT Syndrome; Male; Placebos; Potassium; Procollagen; Spironolactone; Stroke; Survivors; Treatment Outcome | 2013 |
Greater efficacy of aldosterone blockade and diuretic reinforcement vs. dual renin-angiotensin blockade for left ventricular mass regression in patients with resistant hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Amiloride; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Bisoprolol; Blood Pressure; Blood Pressure Determination; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Hypertension; Hypertrophy, Left Ventricular; Irbesartan; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Ramipril; Renin; Renin-Angiotensin System; Spironolactone; Tetrazoles; Young Adult | 2014 |
Indomethacin, amiloride, or eplerenone for treating hypokalemia in Gitelman syndrome.
Topics: Adolescent; Adult; Amiloride; Blood Pressure; Body Weight; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Eplerenone; Female; Gitelman Syndrome; Glomerular Filtration Rate; Heart Rate; Humans; Hypokalemia; Indomethacin; Male; Middle Aged; Potassium; Renin; Spironolactone; Treatment Outcome; Young Adult | 2015 |
Amiloride lowers blood pressure and attenuates urine plasminogen activation in patients with treatment-resistant hypertension.
Topics: Adult; Aged; Albuminuria; Amiloride; Antihypertensive Agents; Blotting, Western; Creatinine; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Therapy, Combination; Epithelial Sodium Channel Blockers; Female; Humans; Hypertension; Kidney Function Tests; Male; Middle Aged; Plasminogen; Spironolactone; Treatment Outcome | 2014 |
120 other study(ies) available for spironolactone and amiloride
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
[Use and abuse of potassium-saving diuretics].
Topics: Amiloride; Humans; Hypertension; Pyrazines; Spironolactone; Substance-Related Disorders | 1979 |
Mechanisms of action and clinical uses of diuretics.
Topics: Amiloride; Animals; Benzothiadiazines; Calcium; Carbonic Anhydrase Inhibitors; Diuretics; Dogs; Edema; Ethacrynic Acid; Furosemide; Humans; Kidney Tubules; Kidney Tubules, Distal; Kidney Tubules, Proximal; Loop of Henle; Mannitol; Rabbits; Sodium; Sodium Chloride Symporter Inhibitors; Spironolactone | 1979 |
Pharmacologic studies in Bartter's syndrome: opposite effects of treatment with antikaliuretic and antiprostaglandin drugs. Part I.
Topics: Adult; Amiloride; Bartter Syndrome; Humans; Hyperaldosteronism; Ibuprofen; Indomethacin; Male; Potassium; Propranolol; Prostaglandin Antagonists; Renin; Sodium; Spironolactone; Time Factors | 1978 |
The treatment of low-renin ("primary") hyperaldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Amiloride; Blood Pressure; Dexamethasone; Female; Humans; Hyperaldosteronism; Male; Potassium; Renin; Spironolactone | 1978 |
Comparison of the antihypertensive and hormonal effects of a cardioselective beta-blocker, acebutolol, and diuretics in essential hypertension.
Topics: Acebutolol; Adult; Aldosterone; Amiloride; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Spironolactone | 1978 |
Modes of action of diuretics.
Topics: Acetazolamide; Amiloride; Animals; Benzothiadiazines; Biological Transport; Canrenoic Acid; Chlorides; Diuresis; Diuretics; Furosemide; Kidney Tubules; Mannitol; Potassium; Rats; Sodium; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene | 1978 |
[Comparison of spironolactone and amiloride combined with hydrochlorothiazide in the treatment of slight or moderate hypertension].
Topics: Amiloride; Blood Glucose; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Spironolactone; Uric Acid | 1978 |
[Spirolactones and potassium-sparing diuretics].
Topics: Amiloride; Edema; Humans; Hyperaldosteronism; Hypertension; Pyrazines; Spironolactone; Triamterene | 1978 |
Clinical use of diuretics in congestive heart failure.
Topics: Amiloride; Benzothiadiazines; Diuretics; Ethacrynic Acid; Female; Furosemide; Heart Failure; Humans; Infant, Newborn; Pregnancy; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene | 1979 |
Potassium-sparing diuretics.
Topics: Aldosterone; Amiloride; Animals; Chlorides; Diuretics; Dogs; Dose-Response Relationship, Drug; Humans; Imidazoles; Kidney; Mineralocorticoid Receptor Antagonists; Natriuresis; Potassium; Rats; Spironolactone; Triamterene | 1977 |
Paradoxical reversal of the suppressed potassium secretion during treatment with combinations of antikaluretic agents (spironolactone, canrenone, triamterene, amiloride); a possible site of action in Henle's loop.
Topics: Amiloride; Canrenone; Humans; Kidney Tubules; Liver Cirrhosis; Loop of Henle; Male; Middle Aged; Potassium; Pregnadienes; Pyrazines; Sodium; Spironolactone; Triamterene | 1976 |
Effect of potassium-sparing diuretics on the renin-angiotensin-aldosterone system and potassium retention in heart failure.
Topics: Adult; Aged; Aldosterone; Amiloride; Angiotensin II; Digoxin; Female; Furosemide; Heart Failure; Humans; Male; Middle Aged; Potassium; Renin; Sodium; Spironolactone; Urea | 1976 |
Opposite effects of spironolactone and amiloride on potassium excretion in a patient with ascites due to liver cirrhosis.
Topics: Amiloride; Ascites; Drug Interactions; Female; Humans; Liver Cirrhosis; Middle Aged; Potassium; Pyrazines; Spironolactone | 1976 |
Reversal of the suppressed potassium excretion during treatment with combinations of antikaliuretic drugs (spironolactone, canrenone, triamterene, amiloride) in patients with liver cirrhosis.
Topics: Amiloride; Ascites; Canrenone; Diuresis; Diuretics; Drug Synergism; Drug Therapy, Combination; Humans; Liver Cirrhosis; Natriuresis; Potassium; Spironolactone; Triamterene | 1976 |
[Potassium-saving effects of amiloride, triamterene and spironolactone].
Topics: Amiloride; Animals; Potassium; Pyrazines; Rats; Spironolactone; Triamterene | 1976 |
Induction of transporting sites in a sodium transporting epithelium.
Topics: Amiloride; Animals; Binding Sites; Biological Transport; Epithelium; In Vitro Techniques; Membrane Potentials; Rana temporaria; Skin; Sodium; Spironolactone | 1976 |
Electrical potential difference, sodium absorption and potassium secretion by the human rectum during carbenoxolone therapy.
Topics: Adult; Aged; Amiloride; Bendroflumethiazide; Carbenoxolone; Dialysis; Electrophysiology; Humans; Hydrocortisone; Intestinal Absorption; Intestinal Mucosa; Middle Aged; Peptic Ulcer; Potassium; Rectum; Sodium; Spironolactone; Triterpenes | 1975 |
Some aspects of diuretic therapy.
Topics: Aged; Amiloride; Benzothiadiazines; Digitalis Glycosides; Diuretics; Drug Therapy, Combination; Ethacrynic Acid; Female; Furosemide; Heart Failure; Humans; Hypokalemia; Magnesium Deficiency; Male; Potassium; Potassium Chloride; Sodium Chloride Symporter Inhibitors; Spironolactone | 1975 |
Azolimine: a nonsteroidal antagonist of the effects of mineralocorticoids on renal electrolyte excretion.
Topics: Adrenal Glands; Adrenalectomy; Amiloride; Animals; Desoxycorticosterone; Dogs; Hydrochlorothiazide; Imidazoles; Imines; Kidney; Male; Mineralocorticoids; Potassium; Rats; Sodium; Spironolactone; Sulfonamides | 1975 |
Potassium metabolism and diuretics administration in liver cirrhosis.
Topics: Amiloride; Diuretics; Humans; Liver Cirrhosis; Potassium; Spironolactone; Triamterene | 1975 |
[Modern diuretic preparations. III. Potassium-saving diuretics].
Topics: Amiloride; Contraindications; Diuretics; Humans; Potassium; Spironolactone; Triamterene | 1992 |
Distal nephron function in Bartter's syndrome: abnormal conductance to chloride in the cortical collecting tubule?
Topics: Adolescent; Adult; Amiloride; Bartter Syndrome; Diuresis; Female; Fludrocortisone; Furosemide; Humans; Kidney Tubules, Collecting; Loop of Henle; Male; Middle Aged; Sodium Chloride; Spironolactone; Sulfates | 1992 |
Diuresis increases ascitic fluid opsonic activity in patients who survive spontaneous bacterial peritonitis.
Topics: Amiloride; Ascites; Bacterial Infections; Complement C3; Complement C4; Diuresis; Humans; Liver Cirrhosis; Opsonin Proteins; Peritonitis; Spironolactone | 1992 |
Dietary restriction sensitizes the rat distal colon to aldosterone.
Topics: Adrenalectomy; Aldosterone; Amiloride; Animals; Biological Transport; Colon; Corticosterone; Food Deprivation; Intestinal Absorption; Rats; Sodium; Spironolactone; Starvation | 1992 |
Glucocorticoids increase Ca2+ uptake and [3H]dihydropyridine binding in A7r5 vascular smooth muscle cells.
Topics: Amiloride; Analysis of Variance; Androstanols; Animals; Calcium; Calcium Channels; Cell Count; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Dihydropyridines; Electric Conductivity; Glucocorticoids; Indomethacin; Kinetics; Muscle, Smooth, Vascular; Potassium; Proteins; Rats; Receptors, Glucocorticoid; Spironolactone; Water | 1991 |
The influence of endogenous mineralocorticoids on the composition of fetal urine.
Topics: Aldosterone; Amiloride; Animals; Chlorides; Female; Fetus; Glomerular Filtration Rate; Mineralocorticoids; Potassium; Pregnancy; Sheep; Sodium; Spironolactone; Urine | 1990 |
[Clinical case: polyneuritis in a cirrhotic patient].
Topics: Amiloride; Female; Humans; Hyperkalemia; Iatrogenic Disease; Liver Cirrhosis; Middle Aged; Organometallic Compounds; Polyneuropathies; Spironolactone | 1990 |
Lithium clearance in healthy humans: effects of sodium intake and diuretics.
Topics: Amiloride; Benzothiadiazines; Bumetanide; Diuretics; Furosemide; Humans; Lithium; Metabolic Clearance Rate; Reference Values; Sodium Chloride Symporter Inhibitors; Sodium, Dietary; Spironolactone | 1990 |
Effects of deoxycorticosterone acetate on the electrical properties of rat large intestine: segmental differences.
Topics: Amiloride; Animals; Cecum; Colon; Desoxycorticosterone; Electrophysiology; Epithelium; Intestine, Large; Ion Channels; Male; Rats; Rats, Inbred Strains; Rectum; Sodium; Spironolactone | 1987 |
The cellular pool of Na+ channels in the amphibian cell line A6 is not altered by mineralocorticoids. Analysis using a new photoactive amiloride analog in combination with anti-amiloride antibodies.
Topics: Affinity Labels; Aldosterone; Amiloride; Animals; Blotting, Western; Cattle; Cell Line; Kidney; Microsomes; Mineralocorticoids; Photochemistry; Sodium Channels; Spectrophotometry, Ultraviolet; Spironolactone; Xenopus laevis | 1989 |
Effect of amiloride on the compensatory renal growth that follows uninephrectomy in mice.
Topics: Amiloride; Animals; Biological Transport; Carrier Proteins; Female; Kidney; Male; Mice; Nephrectomy; Organ Size; Potassium; Proteins; Sodium; Sodium-Hydrogen Exchangers; Spironolactone | 1989 |
Differential effects of corticosteroids on Na+ transport in rat distal colon in vitro.
Topics: Aldosterone; Amiloride; Animals; Biological Transport, Active; Colon; Dexamethasone; Electrophysiology; Ion Channels; Male; Rats; Rats, Inbred Strains; Sodium; Spironolactone; Stimulation, Chemical | 1985 |
Potassium-sparing diuretics and hyperkalaemia--still a problem.
Topics: Amiloride; Heart Arrest; Humans; Hyperkalemia; Potassium; Spironolactone | 1989 |
Effects of corticosteroid hormones on the electrophysiology of rat distal colon: implications for Na+ and K+ transport.
Topics: Aldosterone; Amiloride; Androstanols; Animals; Biological Transport, Active; Colon; Dexamethasone; Male; Membrane Potentials; Potassium; Rats; Rats, Inbred Strains; Sodium; Spironolactone; Tetraethylammonium; Tetraethylammonium Compounds | 1989 |
Regulation of renal peripheral benzodiazepine receptors by anion transport inhibitors.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetazolamide; Amiloride; Animals; Anions; Anthracenes; Biological Transport; Bumetanide; Furosemide; Hydrochlorothiazide; Kidney; Kinetics; Male; Myocardium; Ouabain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spironolactone | 1988 |
Current management of hypertension.
Topics: Adrenergic beta-Antagonists; Amiloride; Antihypertensive Agents; Benzothiadiazines; Diuretics; Humans; Hypertension; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene | 1985 |
Activation of luminal Na+/H+ exchange in distal nephron of frog kidney. An early response to aldosterone.
Topics: Aldosterone; Amiloride; Animals; Carrier Proteins; Electrochemistry; Hydrogen-Ion Concentration; Kidney; Nephrons; Rana pipiens; Sodium-Hydrogen Exchangers; Spironolactone | 1987 |
Long-term metabolic effects of spironolactone and thiazides combined with potassium-sparing agents for treatment of essential hypertension.
Topics: Amiloride; Benzothiadiazines; Blood Glucose; Diuretics; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Potassium; Sodium Chloride Symporter Inhibitors; Spironolactone; Time Factors; Triamterene | 1988 |
Corticosteroid regulation of Na+ and K+ transport in the rat distal colon during postnatal development.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Aging; Aldosterone; Amiloride; Animals; Animals, Suckling; Colon; Corticosterone; Dexamethasone; Estrenes; Mifepristone; Potassium; Rats; Sodium; Spironolactone | 1988 |
Glucocorticoids have a different action than aldosterone on target tissue.
Topics: Adrenalectomy; Aldosterone; Amiloride; Androstanols; Animals; Colon; Electrophysiology; Glucocorticoids; Male; Potassium; Rats; Rats, Inbred Strains; Sodium; Spironolactone | 1988 |
Potassium-sparing diuretics.
Topics: Amiloride; Diuretics; Heart Failure; Humans; Hypokalemia; Magnesium Deficiency; Potassium; Spironolactone; Triamterene; Water-Electrolyte Imbalance | 1986 |
Amiloride-sensitive sodium transport of the rat distal colon during early postnatal development.
Topics: Adrenalectomy; Aldosterone; Amiloride; Animals; Biological Transport; Colon; In Vitro Techniques; Intestinal Mucosa; Male; Membrane Potentials; Rats; Rats, Inbred Strains; Sodium; Spironolactone; Weaning | 1987 |
Aldosterone-induced, amiloride-inhibitable short-circuit current in the avian ileum.
Topics: Aldosterone; Amiloride; Animals; Chickens; Corticosterone; Diet, Sodium-Restricted; Electrophysiology; Ileum; Intestinal Mucosa; Mineralocorticoid Receptor Antagonists; Serous Membrane; Sodium; Spironolactone | 1987 |
Hyperkalemia-induced sick sinus syndrome.
Topics: Aged; Amiloride; Electrocardiography; Female; Humans; Hyperkalemia; Middle Aged; Sick Sinus Syndrome; Spironolactone | 1987 |
Rapid diuresis in patients with ascites from chronic liver disease: the importance of peripheral edema.
Topics: Amiloride; Ascites; Body Weight; Chronic Disease; Diuresis; Edema; Electrolytes; Furosemide; Humans; Liver Diseases; Plasma Volume; Spironolactone; Time Factors | 1986 |
Potassium loss, ventricular irritability, and the risk of sudden death in hypertensive patients.
Topics: Amiloride; Arrhythmias, Cardiac; Death, Sudden; Diuretics; Humans; Hypertension; Hypokalemia; Magnesium Deficiency; Spironolactone | 1986 |
[Principles of treating hypertension patients with diuretics].
Topics: Absorption; Amiloride; Benzothiadiazines; Blood Pressure; Diuresis; Diuretics; Drug Resistance; Humans; Hypertension; Hypokalemia; Kidney; Natriuresis; ortho-Aminobenzoates; Sodium Chloride Symporter Inhibitors; Spironolactone; Time Factors; Triamterene; Water-Electrolyte Balance | 1986 |
Amiloride-sensitive salt and fluid absorption in small intestine of sodium-depleted rats.
Topics: Adrenalectomy; Amiloride; Animals; Body Water; Colon; Diet, Sodium-Restricted; Electric Conductivity; Hyperaldosteronism; Intestinal Absorption; Intestine, Small; Intestines; Male; Membrane Potentials; Pyrazines; Rats; Rats, Inbred Strains; Sodium Chloride; Spironolactone | 1985 |
Arrhythmogenic potential of diuretic induced hypokalaemia in patients with mild hypertension and ischaemic heart disease.
Topics: Amiloride; Arrhythmias, Cardiac; Chlorthalidone; Coronary Disease; Cyclopenthiazide; Diuretics; Female; Hormones; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Potassium; Spironolactone | 1985 |
Spironolactone and amiloride in the treatment of low renin hyperaldosteronism and related syndromes.
Topics: Adrenocortical Hyperfunction; Amiloride; Angiotensin II; Body Water; Corticosterone; Diuretics; Extracellular Space; Humans; Hyperaldosteronism; Hypertension; Plasma Volume; Potassium; Pyrazines; Renin; Secretory Rate; Sodium; Spironolactone; Urea | 1973 |
Adaptation to the natriuretic actions of hydrochlorothiazide, frusemide and amiloride, by rats.
Topics: Adaptation, Physiological; Adrenal Glands; Adrenalectomy; Aldosterone; Amiloride; Animals; Corticosterone; Diuresis; Diuretics; Female; Furosemide; Hydrochlorothiazide; Juxtaglomerular Apparatus; Natriuresis; Potassium; Pyrazines; Rats; Renin; Sodium; Sodium Chloride; Spironolactone; Time Factors | 1972 |
[Letter: Potassium retaining diuretics].
Topics: Amiloride; Humans; Potassium; Pyrazines; Spironolactone; Stimulation, Chemical; Triamterene | 1974 |
Current aspects of diuretic treatment.
Topics: Amiloride; Diuretics; Ethacrynic Acid; Furosemide; Spironolactone; Thiadiazines; Triamterene | 1972 |
[Mechanism of action of diuretics of the anti-aldosterone type].
Topics: Aldosterone; Amiloride; Diuresis; Diuretics; Humans; Kidney; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Spironolactone; Triamterene | 1973 |
Antikaluretic action of amiloride.
Topics: Amiloride; Animals; Calcium; Diuretics; Furosemide; Hydrochlorothiazide; Kidney; Potassium; Pyrazines; Rats; Spironolactone | 1973 |
[Is essential hypertension still a disease entity? Definition of hyporeninemic hypertension].
Topics: Aldosterone; Amiloride; Chlorthalidone; Diagnosis, Differential; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Mineralocorticoids; Prognosis; Renin; Sodium Chloride; Spironolactone; Sympathetic Nervous System | 1974 |
Amiloride in primary hyperaldosteronism with chronic peptic ulceration.
Topics: Aged; Amiloride; Bicarbonates; Blood Pressure; Body Water; Chlorides; Chronic Disease; Diuretics; Female; Humans; Hyperaldosteronism; Hypertension; Peptic Ulcer; Potassium; Pyrazines; Sodium; Spironolactone; Urea | 1973 |
Clinical use of potassium supplements and potassium sparing diuretics.
Topics: Aldosterone; Amiloride; Diuretics; Drug Therapy, Combination; Humans; Hyperkalemia; Hypokalemia; Kidney; Potassium; Spironolactone; Thiazines; Triamterene | 1973 |
[Exchangeable sodium, total-body potassium, plasma volume, and hypotensive effect of various diuretics in patients with essential hypertension and low plasma renin level (author's transl)].
Topics: Adolescent; Adult; Amiloride; Blood Pressure; Blood Volume; Body Surface Area; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Potassium; Renin; Sodium; Spironolactone | 1974 |
Potassium-sparing diuretics: spironolactone v. triamterene and amiloride.
Topics: Amiloride; Costs and Cost Analysis; Diuretics; Humans; Potassium; Spironolactone; Triamterene | 1972 |
[Effect of antikaliuretics on the development of cardiac lesions in potassium or magnesium deficiencies in the rat].
Topics: Amiloride; Animals; Chlorides; Diet; Diuretics; Female; Heart; Heart Diseases; Magnesium; Magnesium Deficiency; Necrosis; Potassium; Potassium Chloride; Potassium Deficiency; Rats; Spironolactone; Stress, Physiological; Triamterene | 1971 |
Diuretics. I. Physiological and pharmacological considerations.
Topics: Acid-Base Equilibrium; Amiloride; Benzothiadiazines; Carbonic Anhydrase Inhibitors; Diuretics; Ethacrynic Acid; Furosemide; Glomerular Filtration Rate; Humans; Kidney; Kidney Concentrating Ability; Kidney Tubules; Mannitol; Organomercury Compounds; Osmosis; Spironolactone; Triamterene; Water-Electrolyte Balance; Xanthines | 1971 |
Secretion and drainage of the cerebrospinal fluid.
Topics: Acetazolamide; Amiloride; Amphotericin B; Arachnoid; Biological Transport, Active; Cerebral Ventricles; Cerebrospinal Fluid; Choroid Plexus; Humans; Ouabain; Pressure; Spironolactone; Subarachnoid Space; Vasopressins | 1971 |
Apparent mineralocorticoid excess and deficient 11 beta-oxidation of cortisol in a young female.
Topics: Adrenocorticotropic Hormone; Adult; Alkalosis; Amiloride; Aminoglutethimide; Dexamethasone; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Hypertension; Hypokalemia; Mineralocorticoids; Oxidation-Reduction; Spironolactone; Syndrome | 1984 |
Secondary effect of aldosterone on Na-KATPase activity in the rabbit cortical collecting tubule.
Topics: Adrenalectomy; Aldosterone; Amiloride; Animals; Biological Transport; Dexamethasone; Female; Kidney Cortex; Kidney Tubules; Kidney Tubules, Collecting; Rabbits; Sodium; Sodium-Potassium-Exchanging ATPase; Spironolactone; Time Factors | 1981 |
Metabolic effects of high dose amiloride and spironolactone: a comparative study in normal subjects.
Topics: Adult; Aldosterone; Amiloride; Angiotensin II; Dose-Response Relationship, Drug; Endocrine Glands; Humans; Male; Metabolism; Mineralocorticoids; Potassium; Pyrazines; Renin; Sodium; Spironolactone; Time Factors | 1984 |
Spironolactone and amiloride in hypertensive patients with and without aldosterone excess.
Topics: Adult; Amiloride; Blood Pressure; Body Weight; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Renin; Spironolactone; Urea | 1980 |
Relative potency of amiloride and spironolactone in healthy man.
Topics: Adult; Amiloride; Dose-Response Relationship, Drug; Humans; Male; Potassium; Pyrazines; Sodium; Spironolactone | 1982 |
[Therapy of cardiac insufficiency with diuretics].
Topics: Amiloride; Benzothiadiazines; Blood Glucose; Diuretics; Drug Administration Schedule; Female; Furosemide; Gynecomastia; Heart Failure; Humans; Hypokalemia; Kidney Diseases; Male; Potassium; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene; Uric Acid | 1982 |
[Diuretics in the therapy of chronic cardiac insufficiency].
Topics: Acetazolamide; Amiloride; Diuretics; Drug Interactions; Ethacrynic Acid; Heart Failure; Humans; Indapamide; Metolazone; Risk; Spironolactone; Sulfonamides; Thiazoles; Ticrynafen; Triamterene | 1982 |
Effects of spironolactone and amiloride on corticosteroid-induced changes in colonic function.
Topics: Adrenal Cortex Hormones; Amiloride; Animals; Biological Transport, Active; Colon; In Vitro Techniques; Jejunum; Male; Perfusion; Pyrazines; Rats; Sodium; Spironolactone; Water | 1981 |
Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients.
Topics: Adult; Aldosterone; Amiloride; Angiotensin II; Bendroflumethiazide; Bicarbonates; Blood Pressure; Diuretics; Female; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Placebos; Potassium; Potassium Chloride; Pyrazines; Sodium; Sodium Chloride Symporter Inhibitors; Spironolactone | 1980 |
Induction of amiloride-sensitive sodium transport in the rat colon by mineralocorticoids.
Topics: Action Potentials; Aldosterone; Amiloride; Animals; Colon; Desoxycorticosterone; Drug Therapy, Combination; Furosemide; Male; Membrane Potentials; Rats; Sodium; Spironolactone | 1980 |
Current-noise analysis of Na absorption in the embryonic coprodeum: stimulation by aldosterone and thyroxine.
Topics: Absorption; Aldosterone; Amiloride; Animals; Chick Embryo; Cloaca; Electric Conductivity; Electrophysiology; Epithelium; Intestinal Absorption; Ion Channel Gating; Ion Channels; Mathematics; Models, Biological; Ouabain; Sodium; Spironolactone; Thyroxine | 1993 |
Glucocorticoid resistance.
Topics: Adrenal Gland Diseases; Amiloride; Child; Dexamethasone; Drug Resistance; Flutamide; Glucocorticoids; Humans; Male; Receptors, Glucocorticoid; Spironolactone | 1994 |
Hypertension and the mineralocorticoid receptor in the brain.
Topics: Adrenalectomy; Aldosterone; Amiloride; Animals; Blood Pressure; Brain; Cerebral Ventricles; Hippocampus; Hypertension; Infusions, Parenteral; Mineralocorticoid Receptor Antagonists; Rats; Receptors, Mineralocorticoid; Spironolactone | 1994 |
Correction of hypokalemia with antialdosterone therapy in Gitelman's syndrome.
Topics: Adult; Aldosterone; Amiloride; Bartter Syndrome; Blood Gas Analysis; Blood Pressure; Creatinine; Drug Therapy, Combination; Female; Humans; Hydrogen-Ion Concentration; Hypokalemia; Kidney Diseases; Kidney Tubules; Magnesium; Magnesium Deficiency; Male; Metabolic Clearance Rate; Middle Aged; Potassium; Renin; Spironolactone; Syndrome | 1994 |
A micellar liquid chromatographic procedure for the determination of amiloride, bendroflumethiazide, chlorthalidone, spironolactone and triamterene in pharmaceuticals.
Topics: Amiloride; Bendroflumethiazide; Chemistry, Pharmaceutical; Chlorthalidone; Chromatography, High Pressure Liquid; Diuretics; Micelles; Spironolactone; Tablets; Triamterene | 1993 |
Differential regulation of Na+-K+-ATPase gene expression by corticosteriods in vascular smooth muscle cells.
Topics: Adrenal Cortex Hormones; Aldosterone; Amiloride; Analysis of Variance; Animals; Aorta, Thoracic; Cells, Cultured; Dexamethasone; Gene Expression Regulation, Enzymologic; Kinetics; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Spironolactone | 1996 |
[Pharmacology of potassium-sparing diuretics].
Topics: Amiloride; Diuretics; Humans; Mineralocorticoid Receptor Antagonists; Potassium; Spironolactone; Triamterene | 1997 |
Aldosterone directly induces Na, K-ATPase alpha 1-subunit mRNA in the renal cortex of rat.
Topics: Aldosterone; Amiloride; Animals; Blood Pressure; Gene Expression Regulation, Enzymologic; Hypertension; Kidney; Rats; Rats, Inbred Strains; RNA, Messenger; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Spironolactone; Time Factors | 1999 |
Rapid effects of aldosterone on sodium-hydrogen exchange in isolated colonic crypts.
Topics: Aldosterone; Amiloride; Animals; Arachidonic Acid; Bicarbonates; Colon; Diuretics; Extracellular Space; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Ion Exchange; Ion Transport; Leukotriene Antagonists; Male; Mineralocorticoid Receptor Antagonists; Phospholipases; Prostaglandin Antagonists; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Kinases; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers; Spironolactone; Transcription, Genetic | 1999 |
Nongenomic regulation of ENaC by aldosterone.
Topics: Aldosterone; Amiloride; Animals; Cyclic AMP; Diuretics; Dogs; Enzyme Inhibitors; Epithelial Cells; Epithelial Sodium Channels; Humans; Ion Channel Gating; Kidney Tubules, Collecting; Lymphocytes; Mice; Patch-Clamp Techniques; Rabbits; Rats; Rats, Sprague-Dawley; Renal Agents; Sodium; Sodium Channels; Spironolactone; Thionucleotides; Vasopressins | 2001 |
Liddle syndrome in a newborn infant.
Topics: Alkalosis; Amiloride; Blood Pressure; Diuretics; Electrolytes; Failure to Thrive; Female; Humans; Hypertension; Hypokalemia; Infant, Newborn; Kidney Diseases; Kidney Function Tests; Radiopharmaceuticals; Spironolactone; Syndrome; Technetium Tc 99m Pentetate; Ultrasonography | 2002 |
Human endothelium: target for aldosterone.
Topics: Aldosterone; Amiloride; Biological Transport; Body Water; Cell Size; Cells, Cultured; Diuretics; Endothelial Cells; Endothelium, Vascular; Humans; Microscopy, Atomic Force; Mineralocorticoid Receptor Antagonists; Receptors, Mineralocorticoid; Sodium; Sodium Channels; Sodium-Hydrogen Exchangers; Spironolactone; Umbilical Veins | 2004 |
The many targets of aldosterone.
Topics: Aldosterone; Amiloride; Body Water; Cell Size; Endothelial Cells; Endothelium, Vascular; Guanidines; Humans; Hypertension; Ion Transport; Membrane Potentials; Potassium; Receptors, Mineralocorticoid; Sodium; Sodium-Hydrogen Exchangers; Spironolactone; Sulfones | 2004 |
Blockade of brain mineralocorticoid receptors or Na+ channels prevents sympathetic hyperactivity and improves cardiac function in rats post-MI.
Topics: Amiloride; Animals; Baroreflex; Blood Pressure; Epithelial Sodium Channels; Male; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Sodium Channel Blockers; Sodium Channels; Spironolactone; Sympathetic Nervous System; Ventricular Function, Left | 2005 |
Gitelman's syndrome presenting as intolerance to statin therapy.
Topics: Adult; Amiloride; Cholesterol; Dose-Response Relationship, Drug; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypokalemia; Kidney Diseases; Magnesium; Muscular Diseases; Pain; Potassium; Pravastatin; Spironolactone; Syndrome | 2005 |
Improvement of blood pressure with inhibition of the epithelial sodium channel in blacks with hypertension.
Topics: Amiloride; Black or African American; Blood Pressure; Diuretics; Drug Synergism; Drug Therapy, Combination; Epithelial Sodium Channels; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Randomized Controlled Trials as Topic; Sodium Channel Blockers; Sodium Channels; Spironolactone; Treatment Outcome | 2005 |
Mechanisms for nongenomic and genomic effects of aldosterone on Na+/H+ exchange in vascular smooth muscle cells.
Topics: Aldosterone; Amiloride; Animals; Cells, Cultured; Eplerenone; Fluorescent Dyes; Genome; Hydrogen-Ion Concentration; Ion Transport; Kinetics; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Rats; Sodium-Hydrogen Exchangers; Spironolactone | 2005 |
Antiangiogenic effects of spironolactone and other potassium-sparing diuretics in human umbilical vein endothelial cells and in fibrin gel chambers implanted in rats.
Topics: Amiloride; Angiogenesis Inhibitors; Animals; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Eplerenone; Fibrin; Humans; Male; Neovascularization, Physiologic; Rats; Rats, Wistar; Sodium Channel Blockers; Spironolactone; Umbilical Veins | 2006 |
Aldosterone and amiloride alter ENaC abundance in vascular endothelium.
Topics: Aldosterone; Amiloride; Blotting, Western; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Diuretics; Endothelial Cells; Epithelial Sodium Channels; Fluorescent Antibody Technique; Humans; Microscopy, Atomic Force; Spironolactone; Umbilical Veins | 2008 |
Amiloride 10 mg is less effective than spironolactone 25 mg in patients with hypertension resistant to a multidrug regime including an angiotensin-blocking agent.
Topics: Aged; Amiloride; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Female; Humans; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Spironolactone | 2007 |
Lessons in the diagnosis and management of Conn's syndrome.
Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Amiloride; Amlodipine; Calcium Channel Blockers; Humans; Hydrocortisone; Male; Middle Aged; Spironolactone | 2007 |
Oxidative stress and the genomic regulation of aldosterone-stimulated NHE1 activity in SHR renal proximal tubular cells.
Topics: Aldosterone; Amiloride; Animals; Cell Line; Cytochalasin B; Dactinomycin; Gene Expression Regulation; Genome; Guanidines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Immunoblotting; Kidney Tubules, Proximal; Methacrylates; Mifepristone; Oxidative Stress; Protein Isoforms; Rats; Rats, Inbred SHR; Receptors, Mineralocorticoid; RNA, Messenger; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Spironolactone; Sulfones | 2008 |
Letter regarding article by Hood et al, "The Spironolactone, Amiloride, Losartan, and Thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio".
Topics: Aldosterone; Amiloride; Antihypertensive Agents; Bendroflumethiazide; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Losartan; Sodium Chloride Symporter Inhibitors; Spironolactone | 2008 |
Mechanisms in the PVN mediating local and central sodium-induced hypertension in Wistar rats.
Topics: Aldosterone; Amiloride; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Cerebrospinal Fluid; Diuretics; Dose-Response Relationship, Drug; Eplerenone; Heart Rate; Hypertension; Injections, Intraventricular; Losartan; Ouabain; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Sodium; Spironolactone | 2009 |
Diuretics.
Topics: Amiloride; Diuretics; Drug Therapy, Combination; Female; Humans; Male; Sodium Chloride Symporter Inhibitors; Sodium Potassium Chloride Symporter Inhibitors; Spironolactone | 2009 |
Update in primary aldosteronism.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Amiloride; Antihypertensive Agents; Chromosomes, Human, Pair 7; Cytochrome P-450 CYP11B2; Diagnosis, Differential; Drug Administration Schedule; Eplerenone; Genetic Linkage; Glucocorticoids; Humans; Hyperaldosteronism; Hypertension; Lod Score; Mineralocorticoid Receptor Antagonists; Spironolactone | 2009 |
Severe respiratory phenotype caused by a de novo Arg528Gly mutation in the CACNA1S gene in a patient with hypokalemic periodic paralysis.
Topics: Adolescent; Amiloride; Amino Acid Substitution; Arginine; Calcium Channels; Calcium Channels, L-Type; Cold Temperature; DNA Mutational Analysis; Genotype; Glycine; Humans; Hypokalemic Periodic Paralysis; Male; Mutation; Potassium; Respiratory Insufficiency; Spironolactone | 2010 |
Effects of central sodium on epithelial sodium channels in rat brain.
Topics: Amiloride; Animals; Biological Transport; Brain; Choroid Plexus; Cytochrome P-450 CYP11B2; Epithelial Sodium Channels; Epithelium; Glucocorticoids; Hypothalamus; Male; Paraventricular Hypothalamic Nucleus; Random Allocation; Rats; Rats, Wistar; Receptors, Mineralocorticoid; RNA, Messenger; Sodium; Sodium, Dietary; Spironolactone | 2010 |
Increased renal alpha-epithelial sodium channel (ENAC) protein and increased ENAC activity in normal pregnancy.
Topics: Amiloride; Animals; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Eplerenone; Female; Immunoblotting; Kidney; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Natriuresis; Plasma Volume; Pregnancy; Proteomics; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channel Blockers; Spironolactone; Up-Regulation | 2010 |
11β-hydroxysteroid dehydrogenase type 2 deficiency accelerates atherogenesis and causes proinflammatory changes in the endothelium in apoe-/- mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Amiloride; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cell Line; Endothelium, Vascular; Eplerenone; Gene Expression Regulation, Enzymologic; Inflammation; Male; Mice; Mice, Knockout; Mineralocorticoid Receptor Antagonists; Sodium Channel Blockers; Spironolactone | 2011 |
Quality of life in patients with bilateral primary aldosteronism before and during treatment with spironolactone and/or amiloride, including a comparison with our previously published results in those with unilateral disease treated surgically.
Topics: Adrenalectomy; Adult; Aged; Aldosterone; Amiloride; Australia; Diuretics; Drug Therapy, Combination; Female; Humans; Hyperaldosteronism; Male; Mental Health; Middle Aged; Mineralocorticoid Receptor Antagonists; Quality of Life; Renin; Social Support; Spironolactone; Surveys and Questionnaires; Treatment Outcome | 2011 |
Effect of aldosterone on the amplification of oncolytic vaccinia virus in human cancer lines.
Topics: Aldosterone; Amiloride; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Hydrocortisone; Hydrogen-Ion Concentration; Liver Neoplasms; Mineralocorticoid Receptor Antagonists; Neuroprotective Agents; Oncolytic Virotherapy; Rabbits; Spironolactone; Vaccinia virus; Virus Replication | 2011 |
Aldosterone is synthesized in and activates bulbospinal neurons through mineralocorticoid receptors and ENaCs in the RVLM.
Topics: Aldosterone; Amiloride; Animals; Aromatase Inhibitors; Calcium; Diuretics; Epithelial Sodium Channels; Eplerenone; Excitatory Postsynaptic Potentials; Fadrozole; Magnesium; Medulla Oblongata; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Spinal Cord; Spironolactone; Tissue Fixation | 2013 |
Primary aldosteronism and impaired natriuresis in mice underexpressing TGFβ1.
Topics: Aldosterone; Amiloride; Angiotensin II; Animals; Blood Pressure; DNA Primers; Gene Expression Regulation; Glomerular Filtration Rate; Hyperaldosteronism; Mice; Mice, Inbred C57BL; Natriuresis; Polymerase Chain Reaction; Renin; Sodium-Potassium-Exchanging ATPase; Spironolactone; Transforming Growth Factor beta1; Urinalysis | 2013 |
Diuretic exposure in premature infants from 1997 to 2011.
Topics: Acetazolamide; Amiloride; Bronchopulmonary Dysplasia; Chlorothiazide; Cohort Studies; Diazoxide; Diuretics; Drug Therapy, Combination; Ethacrynic Acid; Female; Furosemide; Humans; Hydrochlorothiazide; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Male; Mannitol; Metolazone; Off-Label Use; Respiration, Artificial; Retrospective Studies; Spironolactone; Thrombocytopenia | 2015 |
Endothelial sodium channels trigger endothelial salt sensitivity with aging.
Topics: Aging; Amiloride; Animals; Aorta; Endothelium, Vascular; Epithelial Sodium Channels; Mice; Sodium Chloride; Spironolactone; Vascular Stiffness | 2014 |
Aldosterone sensitizes connecting tubule glomerular feedback via the aldosterone receptor GPR30.
Topics: Aldosterone; Amiloride; Animals; Arterioles; Cycloheximide; Dactinomycin; Epithelial Sodium Channels; Eplerenone; Feedback; Kidney Tubules; Male; Rabbits; Receptors, G-Protein-Coupled; Receptors, Mineralocorticoid; Spironolactone | 2014 |
Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies.
Topics: Aldosterone; Amiloride; Antihypertensive Agents; Bisoprolol; Blood Pressure; Doxazosin; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Spironolactone | 2018 |
Fluid retention, aldosterone excess, and treatment of resistant hypertension.
Topics: Aldosterone; Amiloride; Blood Pressure; Hemodynamics; Humans; Hypertension; Spironolactone | 2018 |
Investigation of primary aldosteronism in patients with resistant hypertension.
Topics: Amiloride; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Spironolactone | 2018 |
Mineralocorticoid antagonists and ENaC inhibitors in hyperaldosteronism.
Topics: Amiloride; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Spironolactone | 2019 |
Apparent mineralocorticoid excess: A diagnosis beyond classical causes of severe hypertension in a child.
Topics: Aldosterone; Amiloride; Blood Pressure; Child, Preschool; Female; Humans; Hypertension; Hypokalemia; Mineralocorticoid Excess Syndrome, Apparent; Renin; Spironolactone | 2022 |