spiromustine has been researched along with physostigmine in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Levin, V; Prados, M; Rodriguez, L; Seager, M; Silver, P | 1 |
| Balis, F; Doherty, KM; Ettinger, LJ; Heideman, RL; Jeffries, SL; Kelley, JA; Packer, RJ; Poplack, DG; Reaman, GH; Roth, JS | 1 |
| Brown, TD; Donehower, RC; Ettinger, DS | 1 |
| Baker, LH; Corbett, T; Pazdur, R; Phillips, M; Redman, BG | 1 |
1 trial(s) available for spiromustine and physostigmine
| Article | Year |
|---|---|
A phase I trial of spirohydantoin mustard (NSC 172112) in patients with advanced cancer.
Topics: Adult; Aged; Antineoplastic Agents; Central Nervous System Diseases; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Female; Humans; Hydantoins; Male; Middle Aged; Nausea; Nervous System Neoplasms; Nitrogen Mustard Compounds; Physostigmine; Tomography, X-Ray Computed; Xerostomia | 1986 |
4 other study(ies) available for spiromustine and physostigmine
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Phase II study of spirohydantoin mustard for the treatment of recurrent malignant gliomas.
Topics: Adult; Brain Neoplasms; Diagnosis-Related Groups; Drug Evaluation; Female; Glioma; Humans; Hydantoins; Male; Middle Aged; Nitrogen Mustard Compounds; Physostigmine | 1987 |
A pediatric phase I and pharmacokinetic study of spirohydantoin mustard.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Drug Evaluation; Female; Humans; Hydantoins; Male; Nervous System; Nitrogen Mustard Compounds; Physostigmine; Protein Binding | 1988 |
Phase I trial of spiromustine (NSC 172112) and evaluation of toxicity and schedule in a murine model.
Topics: Animals; Antineoplastic Agents; Cognition Disorders; Consciousness Disorders; Drug Evaluation; Drug Evaluation, Preclinical; Gastrointestinal Diseases; Humans; Hydantoins; Mice; Mice, Inbred Strains; Neoplasms; Nitrogen Mustard Compounds; Physostigmine; Speech Disorders | 1987 |