Page last updated: 2024-08-23

spirogermanium and germanium

spirogermanium has been researched along with germanium in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (97.37)	18.7374
1990's	1 (2.63)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Blaauw, A; Dicke, K; Drewinko, B; Spitzer, G; Vellekoop, L; Zander, A	1
Blum, R; Chang, AY; Donehower, RC; Ettinger, DS; Finkelstein, DM; Green, M; Hahn, RG; Ruckdeschel, JC	1
Badger, AM; DiMartino, MJ; Hanna, N; Lee, JC; Mirabelli, CK; Muirhead, KA	1
Badger, AM; DiMartino, M; Mirabelli, CK	1
Goodman, S	1
Chiuten, DF; Dhingra, HM; Holoye, PY; Murphy, WK; Spitzer, G; Umsawasdi, T; Valdivieso, M	1
Boros, L; Glick, JH; Mann, RB; Neiman, RS; Tsiatis, AA	1
Dexeus, FH; Hossan, B; Logothetis, C; Samuels, ML	1
Brunet, R; Bui, NB; Chauvergne, J; Hoerni, B; Lagarde, C; Le Guillou, M; Richaud, P	1
Balcerzak, S; Crowley, J; Goodwin, JW; Hacker, D; Slavik, M; Tranum, B; Vance, R	1
Crawford, ED; Saiers, JH; Slavik, M; Stephens, RL	1
Gesme, DH; Kennedy, BJ; Vogelzang, NJ	1
Copeland, LJ; Gershenson, DM; Kavanagh, JJ; Krakoff, IH; Saul, PB	1
Brenner, DE; Burnett, LS; Dillon, M; Forastiere, A; Greco, FA; Jones, HW; Rosenshein, NB; Tipping, S; Wiernik, PH	1
Bodurtha, A; Eisenhauer, E; Iscoe, N; Kerr, I; McCulloch, P; Pritchard, K; Quirt, I	1
Connors, JM; Eisenhauer, E; Maroun, J; Quirt, I; Skillings, J	1
Davis, J; Mrema, JE; Slavik, M	1
Blumenschein, GR; Bodey, GP; Legha, SS; Pinnamaneni, K; Yap, HY	1
Chang, YC; Falkson, G; Harper, GR; Khandekar, JD; Kuebler, JP; Tormey, DC	1
Ahlgren, JD; Byrne, PJ; Priego, VM; Schein, PS; Woolley, PV	1
Davis, RB; Green, M; Henderson, E; Rafla, S; Schulman, P	1
Bellamy, AS; Hepburn, PJ; Hill, BT; Masters, JR; Metcalfe, S; Whelan, RD	1
Ajani, JA; Bodey, GP; Legha, SS	1
Blanc, O; Davis, J; Slavik, M	1
Cain, KC; Mehta, CR	1
Bodey, G; Dixon, C; Hagemeister, F; Legha, S	1
Falkson, G; Falkson, HC	1
Brenner, DE; Burnett, L; Dillon, M; Forastiere, A; Greco, FA; Grumbine, F; Jones, HW; Rosenshein, NB; Tipping, S; Wiernik, PH	1
Castronovo, FP; DeLuca, SA; Rhea, JT	1
Rafla, S; Yang, SJ	1
Biegel, JA; Fisher, B; Klein, I; Schwartz, GN	1
Budman, DR; Degnan, TJ; Schulman, P; Vinciguerra, V	1
Budman, DR; Coleman, M; Ginsberg, S; Hanson, J; Perry, M; Schein, P; Weinberg, V; Wood, W	1
Biegel, JA; Boggs, SS; Schwartz, GN	1
Bellamy, AS; Hill, BT; Jenkins, LY; Whatley, SA; Whelan, RD	1
Budman, DR; Degnan, TJ; Pasmantier, M; Schulman, P; Vinciguerra, V; Weiselberg, L	1
Henry, MC; Levine, BS; Port, CD; Rosen, E	1
Wang, YL	1

Reviews

1 review(s) available for spirogermanium and germanium

Article	Year
[Evaluation of health promotive effect of organometallic germanium compounds]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1994, Volume: 28, Issue:6 Topics: Animals; Germanium; Humans; Organometallic Compounds; Radioisotopes; Spiro Compounds	1994

Trials

3 trial(s) available for spirogermanium and germanium

Article	Year
Phase II study of N-methylformamide, spirogermanium, and 4-demethoxydaunorubicin in the treatment of non-small cell lung cancer (EST 3583): an Eastern Cooperative Oncology Group study. Medical and pediatric oncology, 1989, Volume: 17, Issue:3 Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Female; Formamides; Germanium; Humans; Idarubicin; Lung Neoplasms; Male; Middle Aged; Organometallic Compounds; Prognosis; Random Allocation; Remission Induction; Spiro Compounds	1989
Therapeutic effects of organic germanium. Medical hypotheses, 1988, Volume: 26, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Animals; Antineoplastic Agents; Arthritis; Clinical Trials as Topic; Female; Germanium; Humans; Leukemia, Experimental; Lung Neoplasms; Lymphoproliferative Disorders; Malaria; Organometallic Compounds; Osteoporosis; Ovarian Neoplasms; Spiro Compounds	1988
A phase II study of spirogermanium in advanced human malignancy. American journal of clinical oncology, 1985, Volume: 8, Issue:4 Topics: Adult; Aged; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Female; Germanium; Half-Life; Humans; Infusions, Parenteral; Kinetics; Male; Middle Aged; Neoplasms; Organometallic Compounds; Spiro Compounds	1985

Other Studies

34 other study(ies) available for spirogermanium and germanium

Article	Year
Potential drugs for elimination of acute lymphatic leukemia cells from autologous bone marrow. Experimental hematology, 1986, Volume: 14, Issue:7 Topics: Antineoplastic Agents; Asparaginase; Bleomycin; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Line; Cyclophosphamide; Germanium; Hematopoietic Stem Cells; Humans; Kinetics; Leukemia, Lymphoid; Organometallic Compounds; Spiro Compounds; Vincristine	1986
Antiarthritic and immunoregulatory activity of spirogermanium. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis; Arthritis, Experimental; Auranofin; Aurothioglucose; Concanavalin A; Fluorescence; Germanium; Immunosuppressive Agents; Indomethacin; Interleukin-1; Interleukin-2; Macrophages; Male; Monocytes; Organometallic Compounds; Rats; Rats, Inbred Lew; Spiro Compounds; T-Lymphocytes, Regulatory	1986
Generation of suppressor cells in normal rats by treatment with spirogermanium, a novel heterocyclic anticancer drug. Immunopharmacology, 1985, Volume: 10, Issue:3 Topics: Animals; Antineoplastic Agents; Cells, Cultured; Concanavalin A; Germanium; Kinetics; Lymphocyte Depletion; Male; Organometallic Compounds; Rats; Rats, Inbred Lew; Spiro Compounds; Spleen; T-Lymphocytes, Regulatory	1985
Phase II study of spirogermanium in advanced (extensive) non-small cell lung cancer. Cancer treatment reports, 1986, Volume: 70, Issue:5 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Female; Germanium; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Organometallic Compounds; Spiro Compounds	1986
Phase II Eastern Cooperative Oncology Group Study of spirogermanium in previously treated lymphoma. Cancer treatment reports, 1986, Volume: 70, Issue:7 Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Germanium; Humans; Lymphoma; Middle Aged; Organometallic Compounds; Seizures; Spiro Compounds	1986
Phase II study of spirogermanium in metastatic prostate cancer. Cancer treatment reports, 1986, Volume: 70, Issue:9 Topics: Aged; Antineoplastic Agents; Drug Evaluation; Germanium; Humans; Male; Middle Aged; Neoplasm Metastasis; Organometallic Compounds; Prostatic Neoplasms; Spiro Compounds	1986
[Metastatic cancer of the prostate: phase II study of spirogermanium (NSC 192965)]. Bulletin du cancer, 1986, Volume: 73, Issue:1 Topics: Aged; Antineoplastic Agents; Drug Evaluation; Germanium; Humans; Male; Middle Aged; Neoplasm Metastasis; Organometallic Compounds; Prostatic Neoplasms; Spiro Compounds	1986
Phase II trial of spirogermanium in central nervous system tumors: a Southwest Oncology Group Study. Cancer treatment reports, 1987, Volume: 71, Issue:1 Topics: Adult; Aged; Cerebral Hemorrhage; Chemical and Drug Induced Liver Injury; Drug Evaluation; Female; Germanium; Glioma; Humans; Male; Middle Aged; Nervous System Neoplasms; Organometallic Compounds; Spiro Compounds	1987
Therapy for advanced renal cell cancer with spirogermanium: a Southwest Oncology Group Study. Cancer treatment reports, 1987, Volume: 71, Issue:2 Topics: Adult; Aged; Carcinoma, Renal Cell; Drug Evaluation; Female; Germanium; Humans; Kidney Neoplasms; Male; Middle Aged; Organometallic Compounds; Spiro Compounds	1987
Continuous-infusion spirogermanium for the treatment of refractory carcinoma of the ovary: a phase II trial. Cancer treatment reports, 1985, Volume: 69, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Germanium; Humans; Infusions, Parenteral; Middle Aged; Organometallic Compounds; Ovarian Neoplasms; Spiro Compounds	1985
Phase II study of spirogermanium in patients with advanced carcinoma of the cervix. Cancer treatment reports, 1985, Volume: 69, Issue:4 Topics: Adult; Carcinoma, Squamous Cell; Drug Evaluation; Female; Germanium; Humans; Infusions, Parenteral; Middle Aged; Organometallic Compounds; Prognosis; Spiro Compounds; Uterine Cervical Neoplasms	1985
A phase II study of spirogermanium in patients with metastatic malignant melanoma. An NCI Canada Clinical Trials Group Study. Investigational new drugs, 1985, Volume: 3, Issue:3 Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Germanium; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Organometallic Compounds; Spiro Compounds	1985
A phase II study of spirogermanium as second line therapy in patients with poor prognosis lymphoma. An NCI Canada Clinical Trials Group Study. Investigational new drugs, 1985, Volume: 3, Issue:3 Topics: Aged; Antineoplastic Agents; Drug Evaluation; Germanium; Humans; Lymphoma; Middle Aged; Nervous System Diseases; Organometallic Compounds; Prognosis; Spiro Compounds	1985
Spirogermanium: a new drug with antimalarial activity against chloroquine-resistant Plasmodium falciparum. International journal of clinical pharmacology, therapy, and toxicology, 1983, Volume: 21, Issue:4 Topics: Antimalarials; Chloroquine; Drug Resistance, Microbial; Germanium; Organometallic Compounds; Plasmodium falciparum; Spiro Compounds	1983
Phase II study of spirogermanium in the treatment of metastatic breast cancer. Cancer treatment reports, 1984, Volume: 68, Issue:9 Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Central Nervous System Diseases; Drug Evaluation; Female; Germanium; Humans; Infusions, Parenteral; Middle Aged; Organometallic Compounds; Spiro Compounds	1984
Phase II study of spirogermanium in advanced breast cancer. Cancer treatment reports, 1984, Volume: 68, Issue:12 Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Drug Evaluation; Female; Germanium; Humans; Middle Aged; Neoplasm Metastasis; Organometallic Compounds; Receptors, Estrogen; Spiro Compounds	1984
A Phase I trial of spirogermanium administered on a continuous infusion schedule. Investigational new drugs, 1984, Volume: 2, Issue:3 Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Germanium; Humans; Infusions, Parenteral; Male; Middle Aged; Neoplasms; Nervous System; Organometallic Compounds; Phlebitis; Spiro Compounds	1984
Phase II trial of spirogermanium in advanced renal cell carcinoma: a Cancer and Leukemia Group B study. Cancer treatment reports, 1984, Volume: 68, Issue:10 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Germanium; Humans; Kidney Neoplasms; Male; Middle Aged; Organometallic Compounds; Spiro Compounds	1984
Identification of synergistic combinations of spirogermanium with 5-fluorouracil or cisplatin using a range of human tumour cell lines in vitro. Investigational new drugs, 1984, Volume: 2, Issue:1 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Cell Survival; Cisplatin; Colony-Forming Units Assay; Doxorubicin; Drug Synergism; Fluorouracil; Germanium; Humans; Methotrexate; Organometallic Compounds; Spiro Compounds; Tumor Stem Cell Assay	1984
Phase I study of spirogermanium given daily. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:5 Topics: Adult; Aged; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Female; Germanium; Humans; Infusions, Parenteral; Lymphoma; Male; Middle Aged; Nausea; Nervous System Diseases; Organometallic Compounds; Ovarian Neoplasms; Spiro Compounds	1983
Spirogermanium: a new investigational drug of novel structure and lack of bone marrow toxicity. Investigational new drugs, 1983, Volume: 1, Issue:3 Topics: Animals; Antineoplastic Agents; Bone Marrow; Chemical Phenomena; Chemistry; Dogs; Drug Evaluation; Germanium; Humans; Mice; Neoplasms; Neoplasms, Experimental; Organometallic Compounds; Spiro Compounds	1983
Charts for the early stopping of pilot studies. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:6 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Esophageal Neoplasms; False Negative Reactions; Female; Germanium; Humans; Male; Models, Biological; Organometallic Compounds; Pilot Projects; Probability; Sampling Studies; Spiro Compounds; Time Factors	1984
Pulmonary toxicity associated with spirogermanium. Cancer treatment reports, 1984, Volume: 68, Issue:6 Topics: Antineoplastic Agents; Combined Modality Therapy; Drug Evaluation; Female; Germanium; Humans; Lung Diseases; Lymphoma; Male; Middle Aged; Organometallic Compounds; Spiro Compounds	1984
Phase II trial of spirogermanium for treatment of advanced breast cancer. Cancer treatment reports, 1983, Volume: 67, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Drug Evaluation; Female; Germanium; Humans; Middle Aged; Organometallic Compounds; Spiro Compounds	1983
Phase II evaluation of spirogermanium in advanced ovarian carcinoma. Cancer treatment reports, 1983, Volume: 67, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Germanium; Humans; Middle Aged; Organometallic Compounds; Ovarian Neoplasms; Spiro Compounds	1983
The effects of chemotherapy on bony metastases as measured by quantitative skeletal imaging. Clinical nuclear medicine, 1983, Volume: 8, Issue:1 Topics: Adenocarcinoma; Antineoplastic Agents; Bone and Bones; Bone Neoplasms; Colonic Neoplasms; Diphosphonates; Fluorouracil; Germanium; Humans; Male; Middle Aged; Organometallic Compounds; Radionuclide Imaging; Spiro Compounds; Technetium; Technetium Compounds; Time Factors	1983
Effect of spirogermanium on V79 Chinese hamster cells. American journal of clinical oncology, 1983, Volume: 6, Issue:3 Topics: Amphotericin B; Animals; Cell Division; Cell Line; Cell Survival; Chromosome Aberrations; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Germanium; Hot Temperature; Misonidazole; Mitosis; Mitotic Index; Organometallic Compounds; Spiro Compounds	1983
Spirogermanium: effects on hematopoietic stem cells and survival of normal and tumor-bearing mice. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1983, Volume: 173, Issue:2 Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Female; Germanium; Hematopoietic Stem Cells; Lymphoma; Mammary Neoplasms, Experimental; Mice; Mice, Inbred AKR; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Organometallic Compounds; Spiro Compounds; Spleen	1983
Phase I trial of spirogermanium given by infusion in a multiple-dose schedule. Cancer treatment reports, 1982, Volume: 66, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Drug Administration Schedule; Drug Evaluation; Female; Germanium; Humans; Kidney Diseases; Male; Middle Aged; Organometallic Compounds; Spiro Compounds	1982
Phase II trial of spirogermanium in breast adenocarcinoma: a Cancer and Leukemia Group B Study. Cancer treatment reports, 1982, Volume: 66, Issue:8 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Drug Evaluation; Female; Germanium; Humans; Middle Aged; Organometallic Compounds; Spiro Compounds	1982
A model to study drug effects on lymphoma and normal cell populations using the AKR/J mouse. Leukemia research, 1982, Volume: 6, Issue:2 Topics: Animals; Carmustine; Cell Line; Disease Models, Animal; Germanium; Karyotyping; Leukemia, Experimental; Lymphoma; Mice; Mice, Inbred AKR; Neoplasm Transplantation; Organometallic Compounds; Spiro Compounds	1982
Cytotoxic effects and biological activity of 2-aza-8-germanspiro[4,5]-decane-2-propanamine-8,8-diethyl-N,N-dimethyl dichloride (NSC 192965; spirogermanium) in vitro. Cancer research, 1982, Volume: 42, Issue:7 Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Cycle; Cell Line; Cell Survival; Cells, Cultured; Colonic Neoplasms; Cricetinae; Female; Germanium; Humans; Mesocricetus; Neuroblastoma; Neurons; Organometallic Compounds; Ovary; Rats; Spiro Compounds	1982
Phase II trial of spirogermanium in advanced epithelial carcinoma of the ovary. Cancer treatment reports, 1982, Volume: 66, Issue:8 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Female; Germanium; Humans; Middle Aged; Neoplasm Recurrence, Local; Organometallic Compounds; Ovarian Neoplasms; Spiro Compounds	1982
Toxicity of spirogermanium in mice and dogs after iv or im administration. Cancer treatment reports, 1980, Volume: 64, Issue:12 Topics: Animals; Bone Marrow; Dogs; Germanium; Injections, Intramuscular; Injections, Intravenous; Intestines; Lethal Dose 50; Lymphoid Tissue; Mice; Necrosis; Organometallic Compounds; Seizures; Spiro Compounds	1980