Page last updated: 2024-08-16

spiperone and thiophenes

spiperone has been researched along with thiophenes in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cass, WA; Zahniser, NR1
Farooqui, T; Harrold, MW; Miller, DD; Uretsky, N; Wallace, LJ; Wallace, RA1
Butler, R; Christopher, WL; Cipollina, JA; New, JS; Schlemmer, RF; VanderMaelen, CP; Yevich, JP1
Grigoriadis, D; Horn, AS; Seeman, P; Tepper, P; Van der Weide, J; Watanabe, M1
Katzenellenbogen, BS; Toney, TW1
Beart, PM; Cincotta, M; Cook, CJ; de Vries, DJ; Dijkstra, D; Horn, AS; Tepper, P1
O'Boyle, KM; Waddington, JL1
De Vries, JB; Horn, AS; Tepper, PG; Van der Weide, J1
Dell, HD; Schöllnhammer, G; Seidel, PR1
Akunne, HC; Cooke, LW; Davis, MD; Georgic, LM; Heffner, TG; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Shih, YH; Whetzel, SZ; Wise, LD; Wustrow, DJ; Zoski, KT1
Calama, E; Martín, ML; Morán, A; Ortiz de Urbina, AV; San Román, L1
Feng, Z; Hou, T; Li, Y1

Other Studies

12 other study(ies) available for spiperone and thiophenes

ArticleYear
Inhibition of striatal dopamine release by the selective D-2 dopamine receptor agonist N-0437 is blocked by quinine.
    Synapse (New York, N.Y.), 1990, Volume: 5, Issue:4

    Topics: Animals; Binding, Competitive; Corpus Striatum; Dopamine; In Vitro Techniques; Male; Naphthalenes; Quinine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Tetrahydronaphthalenes; Thiophenes

1990
Synthesis and D2 dopaminergic activity of pyrrolidinium, tetrahydrothiophenium, and tetrahydrothiophene analogues of sulpiride.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:4

    Topics: Acetylcholine; Animals; Apomorphine; Cell Membrane; Chemical Phenomena; Chemistry; Corpus Striatum; Dopamine Antagonists; Potassium; Pyrrolidines; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Structure-Activity Relationship; Sulpiride; Thiophenes

1989
The thieno[3,2-c]pyridine and furo[3,2-c]pyridine rings: new pharmacophores with potential antipsychotic activity.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Amphetamines; Animals; Avoidance Learning; Binding, Competitive; Catalepsy; Chemical Phenomena; Chemistry; Dioxanes; Female; Furans; Macaca; Male; Mice; Molecular Structure; Motor Activity; Piperazines; Psychoses, Substance-Induced; Psychotic Disorders; Pyridines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin; Spiperone; Stereotyped Behavior; Structure-Activity Relationship; Thiophenes

1989
Synthesis and radioreceptor binding activity of N-0437, a new, extremely potent and selective D2 dopamine receptor agonist.
    Pharmaceutisch weekblad. Scientific edition, 1985, Oct-25, Volume: 7, Issue:5

    Topics: Animals; Binding, Competitive; In Vitro Techniques; Naphthalenes; Radioligand Assay; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Structure-Activity Relationship; Swine; Tetrahydronaphthalenes; Thiophenes; Tritium

1985
An evaluation of the interactions of antiestrogens with pituitary and striatal dopamine receptors.
    Journal of receptor research, 1987, Volume: 7, Issue:5

    Topics: Animals; Binding, Competitive; Cell Membrane; Corpus Striatum; Diethylamines; Estrogen Antagonists; Female; Nitromifene; Pituitary Gland, Anterior; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Tamoxifen; Thiophenes

1987
Radioreceptor binding reveals the potencies of N,N-disubstituted 2-aminotetralins as D2 dopamine agonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:5

    Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry; Corpus Striatum; Guanosine Triphosphate; Male; Naphthalenes; Phenethylamines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Tetrahydronaphthalenes; Thiophenes

1987
New substituted 1-phenyl-3-benzazepine analogues of SK&F 38393 and N-methyl-thienopyridine analogues of dihydroxynomifensine with selective affinity for the D-1 dopamine receptor in human post-mortem brain.
    Neuropharmacology, 1987, Volume: 26, Issue:12

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Benzazepines; Binding, Competitive; Brain Chemistry; Humans; In Vitro Techniques; Kinetics; Ligands; Nomifensine; Putamen; Pyridines; Receptors, Dopamine; Spiperone; Thiophenes

1987
In vitro binding of the very potent and selective D-2 dopamine agonist, [3H]N-0437 to calf caudate membranes.
    European journal of pharmacology, 1987, Feb-10, Volume: 134, Issue:2

    Topics: Animals; Cattle; Caudate Nucleus; Corpus Striatum; In Vitro Techniques; Kinetics; Membranes; Naphthalenes; Receptors, Dopamine; Spiperone; Tetrahydronaphthalenes; Thiophenes

1987
[Biochemical studies on tienocarbine and related compounds].
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:10

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Binding, Competitive; Brain Chemistry; Catecholamines; Caudate Nucleus; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Indoles; Male; Norepinephrine; Putamen; Rats; Rats, Inbred Strains; Serotonin; Spiperone; Structure-Activity Relationship; Thiophenes

1984
PD 158771, a potential antipsychotic agent with D(2)/D(3) partial agonist and 5-HT(1A) agonist actions. I. Neurochemical effects.
    Neuropharmacology, 2000, Apr-27, Volume: 39, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Benzazepines; Biogenic Amines; Brain Chemistry; Cells, Cultured; CHO Cells; Cricetinae; Dopamine Agonists; Dopamine Antagonists; Electrophysiology; Humans; Male; Membranes; Neostriatum; Piperazines; Pyrimidines; Rats; Rats, Long-Evans; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Spiperone; Tetrahydronaphthalenes; Thiophenes

2000
Vasoconstrictor responses to 5-hydroxytryptamine in the autoperfused hindquarters of spontaneously hypertensive rats.
    Pharmacology, 2004, Volume: 71, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Hindlimb; Indoles; Injections, Intra-Arterial; Injections, Intravenous; Male; Perfusion; Piperazines; Prazosin; Pyridines; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT2; Regional Blood Flow; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Spiperone; Thiophenes; Vasoconstriction

2004
Structure-based drug design for dopamine D3 receptor.
    Combinatorial chemistry & high throughput screening, 2012, Volume: 15, Issue:10

    Topics: Animals; Combinatorial Chemistry Techniques; Drug Design; Haloperidol; Humans; Indoles; Mice; Models, Molecular; Molecular Structure; Piperazines; Piperidines; Pyrazoles; Pyridines; Receptors, Dopamine D3; Spiperone; Structure-Activity Relationship; Sulpiride; Thiophenes

2012