spiperone has been researched along with sulpiride in 142 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 98 (69.01) | 18.7374 |
| 1990's | 30 (21.13) | 18.2507 |
| 2000's | 12 (8.45) | 29.6817 |
| 2010's | 2 (1.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, YZ; Kasliwal, R; Kung, HF; Kung, MP; Mach, RH; Pan, SG | 1 |
| Fang, X; Hu, Z; Levant, B; Min, J; Varady, J; Wang, S; Wu, X | 1 |
| Boeckler, F; Gmeiner, P; Lanig, H | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Gräf, KJ; Horowski, R | 1 |
| Camanni, F; Cocchi, D; Locatelli, V; Massara, F; Müller, EE; Spano, PF; Stefanini, E | 1 |
| Angeby, T; Haglund, L; Köhler, C; Ogren, SO | 2 |
| Garau, L; Govoni, S; Spano, PF; Stefanini, E; Trabucchi, M | 1 |
| Albert, PR; Civelli, O; Liu, YF; Zhou, QY | 1 |
| Done, CJ; Sharp, T | 1 |
| Barton, AC; Black, LE; Sibley, DR | 1 |
| Michel, AD; Nunes, JL; Sharif, NA; Whiting, RL | 1 |
| Bourque, CW; Renaud, LP; Yang, CR | 1 |
| Shippenberg, TS | 1 |
| Bals-Kubik, R; Herz, A; Huber, A; Shippenberg, TS | 1 |
| Frau, M; Gessa, GL; Stefanini, E | 1 |
| Kobayashi, T; Shimizu, H; Toru, M | 1 |
| Gessa, GL; Kuzmin, A; Pani, L; Rossetti, ZL; Stefanini, E | 1 |
| Nowak, JZ; Schorderet, M | 1 |
| Gessa, GL; Olianas, MC; Onali, P | 1 |
| Simmonds, SH; Strange, PG | 1 |
| Jenner, P; Marsden, CD; Rose, S; Weller, ME | 1 |
| Bigornia, L; Napp, D; Ryan, KA; Schneider, AS; Suozzo, M | 1 |
| Boyson, SJ; McGonigle, P; Molinoff, PB; Reuter, S | 1 |
| Farooqui, T; Harrold, MW; Miller, DD; Uretsky, N; Wallace, LJ; Wallace, RA | 1 |
| Hietala, J; Röyttä, M; Syvälahti, E | 2 |
| Chiriboga, CA; De Vivo, DC; Pranzatelli, MR | 1 |
| Hatano, K; Hatazawa, J; Ido, T; Ishiwata, K; Itoh, M; Kawashima, K | 1 |
| Chivers, JK; Jenner, P; Marsden, CD; Reavill, C | 2 |
| Altar, CA; Marshall, JF; O'Neil, S; Walter, RJ | 1 |
| Hashimoto, T; Koda, H; Kuriyama, K | 1 |
| Omeljaniuk, RJ; Peter, RE | 1 |
| Kelly, E; Nahorski, SR; Willcocks, AL | 1 |
| Klassen, NE; Zharkovskiĭ, AM; Zharkovskiĭ, TA | 1 |
| Apud, JA; Masotto, C; Ongini, E; Racagni, G | 1 |
| Andree, TH; Koenig, JI; Meltzer, HY; Mikuni, M; Tong, CY | 1 |
| Aghajanian, GK; Rasmussen, K | 1 |
| Hall, H; Wedel, I | 1 |
| De Souza, EB | 1 |
| Flauto, C; Groppetti, A; Parati, E; Parenti, M; Rusconi, L; Vescovi, A | 1 |
| Coward, D; Urwyler, S | 1 |
| Joyce, JN; Marshall, JF | 1 |
| Bijak, M; Smiałowski, A | 1 |
| Govoni, S; Lucchi, L; Memo, M; Missale, C; Spano, PF; Trabucchi, M | 2 |
| Kaufman, WR; Lindsay, PJ | 1 |
| Contreras, ML; Contreras, PC; Gehlert, DR; O'Donohue, TL; Quirion, R | 1 |
| Cameron, DL; Crocker, AD | 1 |
| Burchill, SA; Thody, AJ | 1 |
| Jenner, P; Marsden, CD; Rupniak, NM | 1 |
| Anderson, D; Gordon, J; Herbster, G; Koller, W; Wack, R | 1 |
| Battaini, F; Di Giovine, S; Govoni, S; Moresco, RM; Trabucchi, M | 1 |
| Clanton, JA; De Paulis, T; Ebert, MH; Janowsky, A; Kessler, RM; Smith, HE | 1 |
| Takebe, K; Watanobe, H | 1 |
| Kohjimoto, Y; Kuwaki, T; Nomura, Y; Ono, T; Satoh, H; Shibayama, F; Shirakawa, K | 1 |
| Jenner, P; Marsden, CD; Simpson, MD | 1 |
| Ozaki, L; Stern, N; Tuck, ML | 1 |
| Jenner, P; Kilpatrick, GJ; Marsden, CD | 2 |
| Agnati, LF; Benfenati, F; Fuxe, K; Goldstein, M; Meller, E | 1 |
| Bouthenet, ML; Brann, M; Hamdi, P; Mann, A; Martres, MP; Redouane, K; Sales, N; Schwartz, JC; Sokoloff, P; Wermuth, CG | 1 |
| Gawell, L; Hall, H; Köhler, C | 1 |
| Randall, PK; Yurek, DM | 1 |
| Csernansky, CA; Csernansky, JG; Hollister, LE | 1 |
| Govoni, S; Memo, M; Spano, PF; Trabucchi, M | 1 |
| Hall, MD; Jenner, P; Marsden, CD; Theodorou, AE | 1 |
| Jenner, P; Marsden, CD; Reavill, C; Theodorou, A | 1 |
| Dyer, R; Hall, MD; Jenner, P; Leigh, N; Marsden, CD; Rupniak, NM | 1 |
| Kitagawa, N; Miyachi, Y; Mizuchi, A; Saruta, S | 1 |
| Briley, M; Langer, SZ; Lehmann, J | 1 |
| Fleminger, S; Hall, MD; Jenner, P; Kerwin, R; Marsden, CD; Murugaiah, K; Rupniak, NM | 1 |
| Fleminger, S; Hall, MD; Jenner, P; Marsden, CD; Rupniak, NM | 1 |
| Ferrer, JM; Mora, F; Sanguinetti, AM; Vives, F | 1 |
| Baldwin, JJ; Martin, GE; McClure, DE; Watling, KJ; Williams, M | 1 |
| Jenner, P; Marsden, CD | 1 |
| Fuxe, K; Köhler, C; Ogren, SO | 1 |
| Dostert, P; Rumigny, JF; Strolin Benedetti, M | 1 |
| Angeby, K; Florvall, L; Hall, H; Köhler, C; Lindbom, LO; Magnusson, O; Ogren, SO | 1 |
| Hitzemann, R; Hom, D; Loh, H; Wu, J | 1 |
| Clément-Cormier, Y; Collu, R; Devoto, P; Marchisio, AM; Stefanini, E; Vernaleone, F | 1 |
| Lin, CW; Wilk, S | 1 |
| Kaufman, WR; Wong, DL | 1 |
| Kuno, T; Tanaka, C | 1 |
| Agid, Y; Bokobza, B; Javoy-Agid, F; Montfort, JC; Ruberg, M | 1 |
| Friedhoff, AJ; Rosengarten, H; Schweitzer, JW | 1 |
| Anene, C; Dowd, FJ; Lau, YS; Runice, C | 1 |
| Covelli, V; Lucchi, L; Petkov, VV; Spano, PF; Trabucchi, M | 1 |
| Dowd, F; Lau, YS; Runice, C | 1 |
| Fleminger, S; Hall, MD; Jenner, P; Kilpatrick, G; Mann, S; Marsden, CD; Rupniak, NM | 1 |
| Hall, MD; Jenner, P; Kilpatrick, G; Marsden, CD; Rupniak, NM | 1 |
| Florvall, L; Hall, H; Ogren, SO | 1 |
| Binkley, K; George, S; Seeman, P | 1 |
| Dubocovich, ML; Zahniser, NR | 1 |
| Collu, R; Hardy, J; Marchisio, AM; Serri, O; Somma, M | 1 |
| Chen, A; Creese, I; Leff, SE | 1 |
| Jenner, P; Marsden, CD; Theodorou, AE | 1 |
| Mason, WT | 1 |
| List, SJ; Seeman, P | 1 |
| Cote, TE; Frey, EA; Grewe, CW; Kebabian, JW | 1 |
| Lazareno, S; Nahorski, SR | 1 |
| Nomura, Y; Oki, K | 1 |
| Barbaccia, ML; Bosio, A; Lucchi, L; Spano, PF; Trabucchi, M | 1 |
| Airaghi, ML; Lucchi, L; Memo, M; Spano, PF; Trabucchi, M | 1 |
| Bannet, J; Belmaker, RH; Ebstein, RP; Gillis, S | 1 |
| Battaini, F; Memo, M; Spano, PF; Trabucchi, M | 1 |
| Bockaert, J; Marchais, D; Tassin, JP | 1 |
| Howlett, DR; Nahorski, SR | 1 |
| Fresia, P; Memo, M; Spano, PF; Stefanini, E; Trabucchi, M | 1 |
| Lucchi, L; Memo, M; Spano, PF; Trabucchi, M | 1 |
| Celander, M; Svartengren, J | 1 |
| Cohen, ML; Gackenheimer, SL; Gehlert, DR; Watts, SW | 1 |
| Nowak, JZ; Zawilska, JB | 1 |
| Burnham, P; Louis, JC; Magal, E; Varon, S | 1 |
| Wallis, DI; Wang, XC; Wu, J | 1 |
| Jeffrey, JJ; Rydelek-Fitzgerald, L; Teitler, M; Wilcox, BD | 1 |
| Allard, S; Falardeau, P; Lapointe, S | 1 |
| Arinami, T; Haga, T; Hamaguchi, H; Ito, K; Itokawa, M; Kameyama, K; Toru, M; Tsuga, H | 1 |
| Ballesteros, JA; Chen, J; Fu, D; Javitch, JA; Weinstein, H | 1 |
| Chen, J; Fu, D; Javitch, JA | 1 |
| Amenta, F; Barili, P; Zaccheo, D | 1 |
| Kołodziejczyk, K; Maj, J; Rogóz, Z; Skuza, G | 1 |
| Andersson, K; Bjelke, B; Chen, Y; Gross, J; Herrera-Marschitz, M; Hillefors-Berglund, M; von Euler, G | 1 |
| Barbier, P; Bravi, D; Colelli, A; Corsini, GU; Maggio, R | 1 |
| Ballesteros, JA; Chen, J; Javitch, JA; Weinstein, H | 1 |
| Fosbraey, P; Kitchen, I; Ridd, MJ | 1 |
| Haga, T; Ito, K; Lameh, J; Sadée, W | 1 |
| Liu, ZH; Zhang, KG | 1 |
| Bradley, RJ; Dwyer, DS; Liu, Y | 1 |
| Kumar, U; Lange, DC; Patel, RC; Patel, SC; Patel, YC; Rocheville, M | 1 |
| Arai, F; Kishimoto, Y; Kondo, Y; Kudo, T; Tada, K | 1 |
| Fu, D; Javitch, JA; Lin, H; Strange, PG; Wilson, J | 1 |
| Bridges, S; Miller, C; Thompson, TL | 1 |
| Chu, J; Wilcox, RE; Wilczynski, W | 1 |
| Castelli, MP; Gessa, GL; Mocci, I; Pani, L; Sanna, AM | 1 |
| Copolov, DL; Dean, B; Goeringer, K; Pavey, G; Scarr, E | 1 |
| Bettinetti, L; Gmeiner, P; Hübner, H | 1 |
| Durand, CJ; Lan, H; Neve, KA; Teeter, MM | 1 |
| Cho, EY; Kim, JH; Kim, KM; Min, C; Park, JH | 1 |
| Feng, Z; Hou, T; Li, Y | 1 |
2 review(s) available for spiperone and sulpiride
| Article | Year |
|---|---|
Retinal dopamine D1 and D2 receptors: characterization by binding or pharmacological studies and physiological functions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Arylamine N-Acetyltransferase; Benzazepines; Colforsin; Cyclic AMP; Dopamine; Ergolines; Light; Quinpirole; Receptors, Dopamine; Retina; Second Messenger Systems; Species Specificity; Spiperone; Sulpiride; Vertebrates | 1990 |
Multiple dopamine receptors in brain and the pharmacological action of substituted benzamide drugs.
Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Benzamides; Brain; Humans; Mice; Motor Activity; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Sodium; Spiperone; Stereotyped Behavior; Sulpiride; Tritium | 1984 |
140 other study(ies) available for spiperone and sulpiride
| Article | Year |
|---|---|
Dopamine D-2 receptor imaging radiopharmaceuticals: synthesis, radiolabeling, and in vitro binding of (R)-(+)- and (S)-(-)-3-iodo-2-hydroxy-6-methoxy-N- [(1-ethyl-2-pyrrolidinyl)methyl]benzamide.
Topics: Animals; Benzamides; Chemical Phenomena; Chemistry; Corpus Striatum; In Vitro Techniques; Iodine Radioisotopes; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship | 1988 |
Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.
Topics: Algorithms; Binding Sites; Computational Biology; Crystallography, X-Ray; Databases, Protein; Humans; Kinetics; Ligands; Lipid Bilayers; Models, Molecular; Molecular Conformation; Mutation; Receptors, Dopamine D2; Receptors, Dopamine D3; Reproducibility of Results; Solvents; Structure-Activity Relationship; Tetrahydronaphthalenes; Water | 2003 |
Modeling the similarity and divergence of dopamine D2-like receptors and identification of validated ligand-receptor complexes.
Topics: Amino Acid Sequence; Animals; Cattle; Conserved Sequence; Dopamine Antagonists; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Dopamine D4; Rhodopsin; Sequence Alignment; Spiperone | 2005 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Neuroendocrine effects of neuropsychotropic drugs and their possible influence on toxic reactions in animals and man -- the role of the dopamine-prolactin system.
Topics: Animals; Dopamine; Ergot Alkaloids; Humans; Lisuride; Neurosecretory Systems; Prolactin; Psychotropic Drugs; Rats; Reserpine; Spiperone; Sulpiride; Time Factors | 1979 |
Prolactin releasing effect of sulpiride isomers in rats and man.
Topics: Adult; Animals; Female; Humans; Isomerism; Male; Pituitary Gland, Anterior; Prolactin; Rats; Spiperone; Sulpiride | 1979 |
Regional displacement by sulpiride of [3H]spiperone binding in vivo. Biochemical and behavioural evidence for a preferential action of limbic and nigral dopamine receptors.
Topics: Animals; Apomorphine; Binding, Competitive; Brain; Butyrophenones; Catalepsy; Haloperidol; Humans; Male; Rats; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Sulpiride | 1979 |
Dopamine receptors: pharmacological and anatomical evidences indicate that two distinct dopamine receptor populations are present in rat striatum.
Topics: Adenylyl Cyclases; Animals; Corpus Striatum; Haloperidol; Male; Rats; Receptors, Dopamine; Spiperone; Sulpiride; Time Factors | 1978 |
Cholera toxin-sensitive 3',5'-cyclic adenosine monophosphate and calcium signals of the human dopamine-D1 receptor: selective potentiation by protein kinase A.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzazepines; Calcium; Calcium Channels; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dopamine; Enzyme Activation; GTP-Binding Proteins; Humans; Inositol Phosphates; Ion Channel Gating; L Cells; Mice; Nifedipine; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Pituitary Gland; Protein Kinases; Rats; Receptors, Dopamine; Signal Transduction; Spiperone; Sulpiride; Virulence Factors, Bordetella | 1992 |
Evidence that 5-HT2 receptor activation decreases noradrenaline release in rat hippocampus in vivo.
Topics: Amphetamines; Animals; DOM 2,5-Dimethoxy-4-Methylamphetamine; Electrophysiology; Hippocampus; Male; Neurons; Norepinephrine; p-Chloroamphetamine; Quipazine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Receptor Agonists; Spiperone; Sulpiride | 1992 |
Agonist-induced desensitization of D2 dopamine receptors in human Y-79 retinoblastoma cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Cell Differentiation; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Down-Regulation; Humans; Pertussis Toxin; Receptors, Dopamine; Retinoblastoma; Spiperone; Sulpiride; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1991 |
Dopamine D2-receptors mediate hypothermia in mice: ICV and IP effects of agonists and antagonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Body Temperature Regulation; Cerebral Ventricles; Domperidone; Dopamine Agents; Dopamine Antagonists; Ergolines; Hypothermia; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Sulpiride | 1991 |
Dopamine D2 receptor activation depolarizes rat supraoptic neurones in hypothalamic explants.
Topics: Animals; Calcium; Dopamine; Dopamine Agents; Ergolines; Membrane Potentials; Neurons; Quinpirole; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Sulpiride; Supraoptic Nucleus | 1991 |
Conditioned reinforcing effects of 8-hydroxy-2-(di-N-propylamino) tetralin: involvement of 5-hydroxytryptamine 1A and D1 dopamine receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzazepines; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Motivation; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Sulpiride; Tetrahydronaphthalenes | 1991 |
Neuroanatomical substrates mediating the aversive effects of D-1 dopamine receptor antagonists.
Topics: Animals; Benzazepines; Brain; Dopamine Antagonists; Injections, Intraventricular; Limbic System; Male; Microinjections; Papaverine; Rats; Rats, Inbred Strains; Receptors, Dopamine D1; Spiperone; Stereotaxic Techniques; Sulpiride; Tetrahydroisoquinolines | 1991 |
Increase in D2 dopamine receptors in the substantia nigra after chronic (-)-sulpiride treatment.
Topics: Animals; Caudate Nucleus; Ketanserin; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Substantia Nigra; Sulpiride; Up-Regulation | 1991 |
[The inhibition of dopamine D1 and D2 receptors in human putamen by antipsychotic drugs].
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Benzamides; Benzazepines; Chlorpromazine; Depression, Chemical; Female; Haloperidol; Humans; In Vitro Techniques; Putamen; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Sulpiride | 1990 |
Flunarizine potentiates cocaine-induced dopamine release and motor stimulation in rats.
Topics: Animals; Brain Chemistry; Cocaine; Corpus Striatum; Dopamine; Drug Synergism; Flunarizine; Male; Membranes; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Sulpiride | 1990 |
Characterization of dopamine receptors mediating inhibition of adenylate cyclase activity in rat striatum.
Topics: Adenylyl Cyclases; Animals; Benzazepines; Bromocriptine; Butaclamol; Corpus Striatum; Dopamine; Enzyme Activation; Ergolines; Guanine Nucleotides; Norepinephrine; Potassium; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sodium; Spiperone; Sulpiride | 1985 |
Inhibition of inositol phospholipid breakdown by D2 dopamine receptors in dissociated bovine anterior pituitary cells.
Topics: Animals; Apomorphine; Biological Assay; Butaclamol; Cattle; Dopamine; In Vitro Techniques; Inositol Phosphates; Phosphatidylinositols; Pituitary Gland, Anterior; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Sugar Phosphates; Sulpiride | 1985 |
In vitro characterisation of dopamine receptors in the superior colliculus of the rat.
Topics: Animals; Apomorphine; Binding, Competitive; Butaclamol; Catecholamines; Corpus Striatum; Haloperidol; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Spiperone; Sulpiride; Superior Colliculi; Synaptosomes | 1987 |
Dopamine receptors on adrenal chromaffin cells modulate calcium uptake and catecholamine release.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Animals; Apomorphine; Butaclamol; Calcium; Calcium Radioisotopes; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Electric Conductivity; Haloperidol; Ion Channels; Nicotine; Potassium; Receptors, Dopamine; Spiperone; Sulpiride | 1988 |
Effects of chronic treatment with selective and nonselective antagonists on the subtypes of dopamine receptors.
Topics: Animals; Benzazepines; Corpus Striatum; Fluphenazine; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Sulpiride | 1989 |
Synthesis and D2 dopaminergic activity of pyrrolidinium, tetrahydrothiophenium, and tetrahydrothiophene analogues of sulpiride.
Topics: Acetylcholine; Animals; Apomorphine; Cell Membrane; Chemical Phenomena; Chemistry; Corpus Striatum; Dopamine Antagonists; Potassium; Pyrrolidines; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Structure-Activity Relationship; Sulpiride; Thiophenes | 1989 |
Dopamine D2 and muscarinic receptor binding characteristics in rat brain after withdrawal of subchronic fluphenazine and sulpiride treatment.
Topics: Animals; Cerebral Cortex; Corpus Striatum; Fluphenazine; Kinetics; Male; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Muscarinic; Reference Values; Spiperone; Substance Withdrawal Syndrome; Sulpiride | 1989 |
Chronic ACTH treatment increases striatal dopamine D-2 receptor binding in developing rat brain.
Topics: Adrenocorticotropic Hormone; Animals; Binding, Competitive; Brain; Corpus Striatum; Limbic System; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Substantia Nigra; Sulpiride | 1989 |
D2-dopamine receptor specific brain uptake of carbon-11-labeled YM-09151-2.
Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Carbon Radioisotopes; Cerebellum; Corpus Striatum; Dogs; Male; Piperidines; Radionuclide Imaging; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Ritanserin; Serotonin Antagonists; Spiperone; Sulpiride | 1989 |
Definition of the in-vivo binding of [3H]spiperone in rat brain using substituted benzamide drugs.
Topics: Amisulpride; Animals; Apomorphine; Benzamides; Binding, Competitive; Brain Chemistry; Female; Haloperidol; Rats; Rats, Inbred Strains; Spiperone; Stereotyped Behavior; Sulpiride | 1989 |
Brain dopamine and serotonin receptor sites revealed by digital subtraction autoradiography.
Topics: Animals; Autoradiography; Brain; Butaclamol; Computers; Ketanserin; Piperidines; Radiographic Image Enhancement; Radionuclide Imaging; Rats; Receptors, Dopamine; Receptors, Serotonin; Spiperone; Sulpiride | 1985 |
Effect of buflomedil (4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxy phenyl)-1-butanone hydrochloride) on the function of striatal dopaminergic neurons.
Topics: Animals; Apomorphine; Benzazepines; Corpus Striatum; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Pyrrolidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Muscarinic; Scopolamine; Spiperone; Sulpiride; Vasodilator Agents | 1989 |
In vitro binding characteristics of [3H]spiperone to the pituitary of the goldfish (Carassius auratus).
Topics: Animals; Binding, Competitive; Cyprinidae; Domperidone; Female; Goldfish; Male; Pituitary Gland; Proteins; Receptors, Dopamine; Spiperone; Sulpiride | 1989 |
Neurochemical and behavioural evidence that dopamine D-2 receptors in striatum couple to the Ni regulatory protein and inhibition of cyclic AMP accumulation.
Topics: Adenylate Cyclase Toxin; Animals; Apomorphine; Behavior, Animal; Benzazepines; Cholera Toxin; Corpus Striatum; Cyclic AMP; Dopamine; GTP-Binding Proteins; In Vitro Techniques; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Sulpiride; Virulence Factors, Bordetella | 1987 |
[Effect of carbidine on the dopamine and serotonin receptors of the central nervous system].
Topics: Animals; Antipsychotic Agents; Brain; Carbolines; Central Nervous System; Haloperidol; Humans; Indoles; Male; Mice; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Spiperone; Stereotyped Behavior; Sulpiride | 1985 |
Interaction of SCH 23390, a D-1-selective antagonist, with the anterior pituitary D-2 receptors and prolactin secretion in the rat.
Topics: Animals; Antipsychotic Agents; Apomorphine; Benzazepines; In Vitro Techniques; Male; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Sulpiride | 1985 |
Differential effect of subchronic treatment with various neuroleptic agents on serotonin2 receptors in rat cerebral cortex.
Topics: 5,7-Dihydroxytryptamine; Animals; Antipsychotic Agents; Cerebral Cortex; Chlorpromazine; Clozapine; Female; Haloperidol; Imipramine; Ketanserin; Loxapine; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Sulpiride | 1986 |
Definition of the in-vivo accumulation of [3H]spiperone in brain using haloperidol and sulpiride to determine functional dopamine receptor occupation.
Topics: Animals; Apomorphine; Brain Chemistry; Corpus Striatum; Female; Haloperidol; Homovanillic Acid; Limbic System; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Sulpiride | 1988 |
Potency of antipsychotics in reversing the effects of a hallucinogenic drug on locus coeruleus neurons correlates with 5-HT2 binding affinity.
Topics: Amphetamines; Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; DOM 2,5-Dimethoxy-4-Methylamphetamine; Electric Stimulation; Evoked Potentials; Haloperidol; Locus Coeruleus; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sciatic Nerve; Spiperone; Sulpiride | 1988 |
Comparisons between the in vitro binding of two substituted benzamides and two butyrophenones to dopamine-D2 receptors in the rat striatum.
Topics: Animals; Benzamides; Butyrophenones; Corpus Striatum; Domperidone; In Vitro Techniques; Ketanserin; Kinetics; Male; Piperidines; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Salicylamides; Spiperone; Sulpiride | 1986 |
Serotonin and dopamine receptors in the rat pituitary gland: autoradiographic identification, characterization, and localization.
Topics: Animals; Autoradiography; Cinanserin; Lysergic Acid Diethylamide; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Spiperone; Sulpiride; Tetrahydronaphthalenes | 1986 |
Dopamine receptor changes in response to prolonged treatment with L-dopa.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Benzazepines; Carbidopa; Corpus Striatum; Dopamine; Hydroxydopamines; Levodopa; Male; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Spiperone; Stereotyped Behavior; Substantia Nigra; Sulpiride | 1986 |
Binding of 3H-spiperone and 3H-(-)-sulpiride to dopamine D2 receptors in rat striatal membranes: methodological considerations and demonstration of the identical nature of the binding sites for the two ligands.
Topics: Animals; Corpus Striatum; Ethylmaleimide; Hydroxydopamines; In Vitro Techniques; Kinetics; Male; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Sulfhydryl Reagents; Sulpiride | 1987 |
Quantitative autoradiography of dopamine D2 sites in rat caudate-putamen: localization to intrinsic neurons and not to neocortical afferents.
Topics: Acetylcholinesterase; Animals; Autoradiography; Caudate Nucleus; Cerebral Cortex; Image Processing, Computer-Assisted; Kinetics; Male; Neural Pathways; Putamen; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Sulpiride | 1987 |
Excitatory and inhibitory action of dopamine on hippocampal neurons in vitro. Involvement of D2 and D1 receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Culture Techniques; Dopamine; Dopamine Antagonists; Haloperidol; Hippocampus; Male; Neurons; Pergolide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Sulpiride | 1987 |
Chronic lead exposure alters dopaminergic mechanisms in rat pituitary.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding, Competitive; Bromocriptine; Cyclic AMP; Dopamine; Female; Lead; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Sulpiride | 1986 |
Potentiation of salivary fluid secretion in ixodid ticks: a new receptor system for gamma-aminobutyric acid.
Topics: Animals; Bicuculline; Dopamine; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Picrotoxin; Receptors, GABA-A; Saliva; Spiperone; Sulpiride; Ticks | 1986 |
Autoradiographic distribution of non-dopaminergic binding sites labeled by [3H]haloperidol in rat brain.
Topics: Animals; Autoradiography; Benzazepines; Binding, Competitive; Brain; Haloperidol; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma; Spiperone; Sulpiride | 1987 |
Alkylation of striatal dopamine receptors abolishes stereotyped behavior but has no effect on dopamine stimulated adenylate cyclase activity.
Topics: Adenylyl Cyclases; Alkylating Agents; Animals; Apomorphine; Benzazepines; Corpus Striatum; Male; Quinolines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Sulpiride | 1988 |
Dopaminergic inhibition of tyrosinase activity in hair follicular melanocytes of the mouse.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Benzazepines; Bromocriptine; Catechol Oxidase; Depression, Chemical; Dopamine; Ergolines; Female; Hair; Haloperidol; Male; Melanocytes; Mice; Mice, Inbred C3H; Monophenol Monooxygenase; Quinpirole; Skin; Spiperone; Sulpiride | 1986 |
Differential alteration of striatal D-1 and D-2 receptors induced by the long-term administration of haloperidol, sulpiride or clozapine to rats.
Topics: Animals; Apomorphine; Clozapine; Corpus Striatum; Dibenzazepines; Dose-Response Relationship, Drug; Haloperidol; Humans; Kinetics; Long-Term Care; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Stereotyped Behavior; Sulpiride; Thioxanthenes | 1985 |
Comparison of neuroleptic binding characteristics in rat striatum and renal cortex.
Topics: Animals; Corpus Striatum; In Vitro Techniques; Kidney Cortex; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereoisomerism; Sulpiride | 1988 |
Quinpirole hydrochloride, a potential anti-parkinsonism drug.
Topics: Animals; Benzazepines; Corpus Striatum; Dogs; Dose-Response Relationship, Drug; Ergolines; Grooming; Haloperidol; Male; Motor Activity; Parkinson Disease; Quinpirole; Rats; Rats, Inbred Strains; Spiperone; Stereotyped Behavior; Sulpiride | 1987 |
Effect of chronic calcium antagonist treatment on dopamine recognition sites in rat striatum.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Corpus Striatum; Flunarizine; Male; Nimodipine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Subcellular Fractions; Sulpiride; Time Factors | 1988 |
[125I]iodopride: a specific high affinity radioligand for labelling striatal dopamine D-2 receptors.
Topics: Animals; Benzamides; Binding, Competitive; Corpus Striatum; Dopamine; In Vitro Techniques; Iodine Radioisotopes; Ligands; Male; Pyrrolidines; Rats; Receptors, Dopamine; Spiperone; Sulpiride | 1988 |
Involvement of postnatal gonads in the maturation of dopaminergic regulation of prolactin secretion in female rats.
Topics: Age Factors; Animals; Animals, Newborn; Dopamine; Estradiol; Female; Ovariectomy; Ovary; Pituitary Gland, Anterior; Progesterone; Prolactin; Rats; Receptors, Dopamine; Spiperone; Sulpiride | 1987 |
Effect of long-term dosing with tiapride on brain dopamine receptors and metabolism in rats. Comparative study with sulpiride and haloperidol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Apomorphine; Benzamides; Brain Chemistry; Dopamine; Haloperidol; Homovanillic Acid; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Sulpiride; Tiapamil Hydrochloride | 1987 |
Effect of lead exposure on dopaminergic receptors in rat striatum and nucleus accumbens.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Corpus Striatum; Female; Haloperidol; Lead Poisoning; Male; Nucleus Accumbens; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Dopamine; Septal Nuclei; Spiperone; Sulpiride | 1986 |
Hyperprolactinaemia does not alter specific striatal 3H-spiperone binding in the rat.
Topics: Animals; Corpus Striatum; Dopamine; Haloperidol; In Vitro Techniques; Male; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Sulpiride; Tritium | 1986 |
Evidence for dopaminergic binding sites in the human adrenal cortex.
Topics: Adrenal Cortex; Adult; Aged; Apomorphine; Binding, Competitive; Bromocriptine; Domperidone; Dopamine; Epinephrine; Female; Humans; Ketanserin; Male; Metoclopramide; Middle Aged; Receptors, Dopamine; Spiperone; Sulpiride; Time Factors | 1986 |
Specific [3H]piflutixol binding to CHAPS-solubilised rat striatal preparations involves dopamine D-2 but not D-1 binding sites.
Topics: Animals; Binding Sites; Binding, Competitive; Cholic Acids; Chromatography, Gel; Corpus Striatum; Flupenthixol; Isomerism; Kinetics; Rats; Receptors, Dopamine; Solubility; Spiperone; Sulpiride; Thioxanthenes | 1986 |
Analysis of [3H]spiperone binding sites in the rat striatum and frontoparietal cortex by means of quantitative receptor autoradiography after inactivation of dopamine receptors by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline in vivo: selective protectio
Topics: Animals; Autoradiography; Butyrophenones; Cerebral Cortex; Corpus Striatum; Male; Quinolines; Rats; Receptors, Dopamine; Spiperone; Sulpiride | 1986 |
The use of [3H](-)-DO 710 as selective dopaminergic ligand for binding and autoradiographic studies.
Topics: Animals; Autoradiography; Brain; Domperidone; Freezing; In Vitro Techniques; Kinetics; Ligands; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Sulpiride; Tritium | 1985 |
Some in vitro receptor binding properties of [3H]eticlopride, a novel substituted benzamide, selective for dopamine-D2 receptors in the rat brain.
Topics: Animals; Brain; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Salicylamides; Sodium; Spiperone; Sulpiride; Tritium | 1985 |
Simultaneous catalepsy and apomorphine-induced stereotypic behavior in mice.
Topics: Animals; Apomorphine; Catalepsy; Chlorpromazine; Domperidone; Drug Interactions; Haloperidol; Injections, Intraventricular; Mice; Spiperone; Stereotyped Behavior; Sulpiride | 1985 |
3[H]-Sulpiride labels mesolimbic non-dopaminergic sites that bind antidepressant drugs.
Topics: Amygdala; Animals; Antidepressive Agents; Binding Sites; Binding, Competitive; Corpus Striatum; Kinetics; Male; Metoclopramide; Nucleus Accumbens; Rats; Septal Nuclei; Spiperone; Sulpiride; Tiapamil Hydrochloride | 1985 |
The binding of [3H]N-(chloroethyl)-norapomorphine to rat striatal membranes.
Topics: Amisulpride; Animals; Aporphines; Binding, Competitive; Butaclamol; Corpus Striatum; Dopamine Antagonists; Female; Flupenthixol; Hydrogen-Ion Concentration; In Vitro Techniques; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereoisomerism; Sulpiride; Tritium | 1984 |
Similarities and dissimilarities between dopamine and neuroleptic receptors: further evidence for type 1 and type 2 dopamine receptors in the CNS.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Brain; Corpus Striatum; In Vitro Techniques; Kinetics; Male; Rats; Receptors, Dopamine; Receptors, Drug; Spiperone; Subcellular Fractions; Sulpiride; Synaptosomes | 1980 |
Cation regulation differentiates specific binding of [3H]sulpiride and [3H]spiperone to rat striatal preparations.
Topics: Animals; Butyrophenones; Calcium; Corpus Striatum; Female; In Vitro Techniques; Magnesium; Potassium; Rats; Receptors, Dopamine; Sodium; Spiperone; Sulpiride | 1980 |
Kainic acid lesions of striatum and decortication reduce specific [3H]sulpiride binding in rats, so D-2 receptors exist post-synaptically on corticostriate afferents and striatal neurons.
Topics: Animals; Binding Sites; Cerebral Cortex; Corpus Striatum; Decerebrate State; Female; Hydroxydopamines; Kainic Acid; Kinetics; Neurons, Afferent; Pyrrolidines; Rats; Spiperone; Sulpiride | 1981 |
Hypophysectomy does not prevent development of striatal dopamine receptor supersensitivity induced by repeated neuroleptic treatment.
Topics: Animals; Antipsychotic Agents; Corpus Striatum; Drug Resistance; Haloperidol; Humans; Hypophysectomy; Luteinizing Hormone; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Sulpiride | 1981 |
Characteristics of [3H]sultopride binding to rat brain.
Topics: Amisulpride; Animals; Antipsychotic Agents; Brain; Cations; Corpus Striatum; In Vitro Techniques; Kinetics; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Spiperone; Sulpiride | 1982 |
Characterization of dopamine autoreceptor and [3H]spiperone binding sites in vitro with classical and novel dopamine receptor agonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic alpha-Agonists; Animals; Apomorphine; Benzazepines; Binding Sites; Bromocriptine; Butyrophenones; Cats; Caudate Nucleus; Dopamine; Electric Stimulation; Female; In Vitro Techniques; Male; Phentolamine; Receptors, Dopamine; Spiperone; Sulpiride; Tritium | 1983 |
Long-term adaptive changes in striatal dopamine function in response to chronic neuroleptic intake in rats.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Apomorphine; Corpus Striatum; Glutamates; Glutamic Acid; Haloperidol; Rats; Receptors, Dopamine; Spiperone; Sulpiride | 1983 |
Changes in apomorphine-induced stereotypy as a result of subacute neuroleptic treatment correlates with increased D-2 receptors, but not with increases in D-1 receptors.
Topics: Animals; Antipsychotic Agents; Apomorphine; Brain; Drug Synergism; Flupenthixol; Haloperidol; Humans; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Stereotyped Behavior; Sulpiride; Thioxanthenes | 1983 |
Effects of agonists and antagonists of D1 and D2 dopamine receptors on self-stimulation of the medial prefrontal cortex in the rat.
Topics: Animals; Apomorphine; Bromocriptine; Cerebral Cortex; Dose-Response Relationship, Drug; Ergolines; Functional Laterality; Male; Pimozide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Self Stimulation; Spiperone; Sulpiride; Synaptic Transmission | 1983 |
Interaction of the component enantiomers of the putative dopamine autoreceptor agonist, TL-99 (6,7-dihydroxy-2-dimethylamino tetralin) with dopaminergic systems in mammalian brain and teleost retina.
Topics: Adrenergic alpha-Agonists; Animals; Apomorphine; Brain; Female; Fishes; Male; Mice; Motor Activity; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Retina; Spiperone; Stereoisomerism; Sulpiride; Tetrahydronaphthalenes; Yohimbine | 1983 |
Studies on the mechanism of action of substituted benzamide drugs.
Topics: Animals; Antipsychotic Agents; Apomorphine; Benzamides; Brain; Catalepsy; Corpus Striatum; Humans; Hyperkinesis; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Substantia Nigra; Sulpiride; Tritium | 1984 |
Investigation on central dopaminergic receptors (D-2) using the antagonistic properties of new benzamides.
Topics: Animals; Apomorphine; Benzamides; Brain; Corpus Striatum; In Vitro Techniques; Male; Mice; Molecular Conformation; Nortropanes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Structure-Activity Relationship; Sulpiride | 1984 |
Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brain.
Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Benzamides; Binding, Competitive; Brain Chemistry; Catalepsy; Chlorpromazine; Dogs; Female; Haloperidol; Histocytochemistry; Humans; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Remoxipride; Spiperone; Sulpiride; Thioridazine; Vomiting | 1984 |
Brain locations controlling the behavioral effects of chronic amphetamine intoxication.
Topics: Adenylyl Cyclases; Animals; Behavior; Brain; Butaclamol; Caudate Nucleus; Dextroamphetamine; Female; Humans; Nucleus Accumbens; Rats; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Sulpiride | 1980 |
Sodium-dependent interaction of benzamides with dopamine receptors in rat and dog anterior pituitary glands.
Topics: Animals; Benzamides; Butaclamol; Dogs; Male; Pituitary Gland, Anterior; Rats; Receptors, Dopamine; Sodium Chloride; Spiperone; Sulpiride; Tetrahydronaphthalenes | 1981 |
A comparison of the effect of substituted benzamides in radioreceptor binding assays with their effects on brain dopaminergic systems in vivo.
Topics: Amisulpride; Animals; Benzamides; Brain; Butaclamol; Cattle; Corpus Striatum; Dihydroergotoxine; Dopamine; In Vitro Techniques; Olfactory Bulb; Radioligand Assay; Spiperone; Sulpiride; Tiapamil Hydrochloride | 1982 |
Evidence for multiple receptors mediating fluid secretion in salivary glands of ticks.
Topics: Animals; Butaclamol; Catecholamines; Deoxyepinephrine; Dopamine; Ergonovine; Female; In Vitro Techniques; Receptors, Neurotransmitter; Salivary Glands; Spiperone; Stereoisomerism; Sulpiride; Ticks; Tranylcypromine | 1983 |
Correspondency between different affinity states and target size of the bovine striatal D2 dopamine receptor.
Topics: Acetylcholinesterase; Animals; Apomorphine; Butaclamol; Cattle; Cell Membrane; Corpus Striatum; Dopamine; Guanosine Triphosphate; Kinetics; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Sulpiride | 1983 |
[3H]spiperone binding in the nigrostriatal system in human brain.
Topics: Aged; Apomorphine; Binding, Competitive; Butaclamol; Butyrophenones; Caudate Nucleus; Cinanserin; Corpus Striatum; Domperidone; Female; Haloperidol; Humans; In Vitro Techniques; Kinetics; Male; Nerve Endings; Phentolamine; Postmortem Changes; Putamen; Spiperone; Substantia Nigra; Sulpiride; Time Factors | 1984 |
Induction of oral dyskinesias in naive rats by D1 stimulation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzazepines; Dyskinesia, Drug-Induced; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Sulpiride | 1983 |
Chronic sulpiride increased 3H-spiperone binding and calmodulin dependent phosphorylation in rat striatum.
Topics: Animals; Apomorphine; Butyrophenones; Calcium; Calcium-Binding Proteins; Calmodulin; Corpus Striatum; Cyclic AMP; Humans; Male; Phosphorylation; Rats; Spiperone; Stereotyped Behavior; Sulpiride | 1983 |
Effects of ethanol, given during pregnancy, on the offspring dopaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dextroamphetamine; Dopamine; Ethanol; Female; Haloperidol; Kinetics; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Spiperone; Sulpiride; Synaptic Transmission | 1983 |
Role of calmodulin-dependent phosphorylation in chronic sulpiride-induced striatal dopamine receptor supersensitivity.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Calmodulin; Corpus Striatum; Cyclic AMP; Male; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Sulpiride | 1984 |
Differential effects of continuous administration for 1 year of haloperidol or sulpiride on striatal dopamine function in the rat.
Topics: Acetylcholine; Animals; Apomorphine; Body Weight; Corpus Striatum; Haloperidol; Humans; Kinetics; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Sulpiride | 1984 |
Differential alterations in striatal dopamine receptor sensitivity induced by repeated administration of clinically equivalent doses of haloperidol, sulpiride or clozapine in rats.
Topics: Animals; Apomorphine; Clozapine; Corpus Striatum; Dibenzazepines; Haloperidol; Humans; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Sulpiride | 1984 |
Effect of lipophilicity of substituted benzamides on the dopaminergic effects in vivo and in vitro.
Topics: Animals; Benzamides; Binding, Competitive; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Lipids; Male; Metoclopramide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Sulpiride | 1984 |
Dopamine receptor sites and states in human brain.
Topics: Brain; Dopamine; Guanine Nucleotides; Humans; Receptors, Dopamine; Spiperone; Substrate Specificity; Sulpiride | 1983 |
Comparison of dopamine receptor sites labeled by [3H]-S-sulpiride and [3H]-spiperone in striatum.
Topics: Animals; Binding Sites; Butyrophenones; Corpus Striatum; Male; Rabbits; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Sulpiride; Tritium | 1983 |
Interaction of sulpiride with human pituitary dopaminergic receptors is sodium dependent.
Topics: Binding, Competitive; Humans; In Vitro Techniques; Pituitary Gland, Anterior; Receptors, Dopamine; Sodium; Sodium Chloride; Spiperone; Sulpiride | 1984 |
Sulpiride isomers exhibit reversed stereospecificity for D-1 and D-2 dopamine receptors in the CNS.
Topics: Animals; Brain Chemistry; Corpus Striatum; Flupenthixol; In Vitro Techniques; Rats; Receptors, Dopamine; Spiperone; Stereoisomerism; Sulpiride | 1984 |
Cation specificity of 3H-sulpiride binding involves alteration in the number of striatal binding sites.
Topics: Animals; Binding Sites; Cations; Cesium; Corpus Striatum; Female; Kinetics; Lithium; Potassium; Rats; Rats, Inbred Strains; Rubidium; Sodium; Spiperone; Sulpiride | 1983 |
Excitation by dopamine of putative oxytocinergic neurones in the rat supraoptic nucleus in vitro: evidence for two classes of continuously firing neurones.
Topics: Animals; Apomorphine; Dopamine; Electric Conductivity; Kinetics; Neurons; Oxytocin; Rats; Spiperone; Sulpiride; Supraoptic Nucleus | 1983 |
Resolution of dopamine and serotonin receptor components of [3H]spiperone binding to rat brain regions.
Topics: Animals; Binding, Competitive; Brain; Brain Mapping; Butyrophenones; Cell-Free System; Cerebral Cortex; Corpus Striatum; Kinetics; Olfactory Bulb; Rats; Receptors, Dopamine; Receptors, Serotonin; Spiperone; Sulpiride | 1981 |
[3H]spiroperidol identifies a D-2 dopamine receptor inhibiting adenylate cyclase activity in the intermediate lobe of the rat pituitary gland.
Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Binding, Competitive; Butyrophenones; Cholera Toxin; Fluphenazine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Male; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Sulpiride | 1982 |
Selective labelling of dopamine (D2) receptors in rat striatum by [3H]domperidone but not by [3H]spiperone.
Topics: Animals; Binding Sites; Butyrophenones; Corpus Striatum; Domperidone; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Spiperone; Sulpiride; Tritium | 1982 |
Development of inhibitory activity of sulpiride for synaptic [3H]-spiperone binding in the rat striatum.
Topics: Aging; Animals; Binding, Competitive; Butyrophenones; Corpus Striatum; Female; Guanosine Triphosphate; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sodium; Spiperone; Sulpiride; Synapses | 1982 |
Regional blockade by neuroleptic drugs of in vivo 3H-spiperone binding in the rat brain. Relation to blockade of apomorphine induced hyperactivity and stereotypies.
Topics: Animals; Apomorphine; Binding, Competitive; Brain; Butyrophenones; Chlorpromazine; Clozapine; Haloperidol; Humans; Hyperkinesis; Kinetics; Organ Specificity; Rats; Receptors, Dopamine; Receptors, Drug; Spiperone; Stereotyped Behavior; Sulpiride; Thioridazine | 1981 |
Neuronal mechanisms regulating ethanol effects on the dopaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Dopamine; Ethanol; Haloperidol; Humans; Male; Morphine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Sulpiride | 1982 |
Chronic lead treatment induces in rat a specific and differential effect on dopamine receptors in different brain areas.
Topics: Adenylyl Cyclases; Animals; Brain; Dopamine; Haloperidol; Kinetics; Lead Poisoning; Motor Activity; Organ Specificity; Rats; Receptors, Dopamine; Spiperone; Sulpiride; Tritium | 1981 |
Effect of chronic sulpiride on striatal spiperone binding.
Topics: Animals; Butyrophenones; Corpus Striatum; Haloperidol; Rats; Spiperone; Sulpiride; Tritium; Visual Cortex | 1980 |
Sulpiride and the role of dopaminergic receptor blockade in the antipsychotic activity of neuroleptics.
Topics: Adenylyl Cyclases; Animals; Corpus Striatum; Drug Interactions; Haloperidol; Male; Rats; Receptors, Dopamine; Spiperone; Sulpiride | 1981 |
Dopaminergic component of [3H]spiroperidol binding in the rat anterior cerebral cortex.
Topics: Animals; Binding, Competitive; Butyrophenones; Corpus Striatum; Dopamine; Frontal Lobe; Rats; Receptors, Dopamine; Receptors, Serotonin; Spiperone; Sulpiride; Tetrahydronaphthalenes | 1980 |
Quantitative assessment of heterogeneous 3H-spiperone binding to rat neostriatum and frontal cortex.
Topics: Animals; Binding Sites; Binding, Competitive; Butyrophenones; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Frontal Lobe; Male; Rats; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Spiperone; Sulpiride | 1980 |
Detection of multiple receptors for dopamine.
Topics: Adenylyl Cyclases; Animals; Brain; Brain Mapping; Butyrophenones; Corpus Striatum; Dopamine; Kainic Acid; Kinetics; Rats; Receptors, Dopamine; Spiperone; Sulpiride | 1980 |
Aging process affects a single class of dopamine receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Aging; Animals; Corpus Striatum; Haloperidol; Humans; Male; Receptors, Dopamine; Spiperone; Sulpiride | 1980 |
The limbic functional selectivity of amperozide is not mediated by dopamine D2 receptors as assessed by in vitro and in vivo binding.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Clozapine; Dopamine; In Vitro Techniques; Limbic System; Male; Neostriatum; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Spiperone; Sulpiride | 1994 |
Autoradiographic comparison of [125I]LSD-labeled 5-HT2A receptor distribution in rat and guinea pig brain.
Topics: Animals; Autoradiography; Binding, Competitive; Guinea Pigs; Iodine Radioisotopes; Kinetics; Lysergic Acid Diethylamide; Male; Organ Specificity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Species Specificity; Spiperone; Sulpiride | 1994 |
Dopamine receptor regulating serotonin N-acetyltransferase activity in chick retina represents a D4-like subtype: pharmacological characterization.
Topics: Animals; Arylamine N-Acetyltransferase; Benzamides; Benzazepines; Chickens; Circadian Rhythm; Clozapine; Dopamine; Dopamine Antagonists; Ergolines; Ketanserin; Male; Quinpirole; Receptors, Dopamine; Retina; Spiperone; Sulpiride | 1994 |
Convergent regulation by ciliary neurotrophic factor and dopamine of tyrosine hydroxylase expression in cultures of rat substantia nigra.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzazepines; Cells, Cultured; Ciliary Neurotrophic Factor; Dopamine; Dose-Response Relationship, Drug; Embryo, Mammalian; Ergolines; Glial Fibrillary Acidic Protein; Haloperidol; Kinetics; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neurotransmitter Agents; Phosphopyruvate Hydratase; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Recombinant Proteins; Spiperone; Substantia Nigra; Sulpiride; Time Factors; Tyrosine 3-Monooxygenase | 1993 |
Is 5-hydroxytryptamine mediating descending inhibition in the neonatal rat spinal cord through different receptor subtypes?
Topics: Animals; Animals, Newborn; Citalopram; Dioxanes; Dopamine Antagonists; Electric Stimulation; Ketanserin; Lumbar Vertebrae; Methiothepin; Methysergide; Rats; Receptors, Serotonin; Reflex, Monosynaptic; Serotonin; Spinal Cord; Spinal Nerve Roots; Spiperone; Spiro Compounds; Sulpiride; Sumatriptan | 1993 |
Serotonin-mediated 5-HT2 receptor gene regulation in rat myometrial smooth muscle cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Biguanides; Cells, Cultured; Cycloheximide; Female; Gene Expression Regulation; Ketanserin; Medroxyprogesterone Acetate; Myometrium; Piperazines; Quipazine; Rats; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sulpiride; Transcription, Genetic; Up-Regulation | 1993 |
Specific induction of a functional endogenous D2 short dopamine receptor in GH4C1 cells.
Topics: Animals; Apomorphine; Base Sequence; Colforsin; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Ergolines; Gene Expression; Kanamycin Kinase; Kinetics; Molecular Sequence Data; Oligodeoxyribonucleotides; Phosphotransferases; Pituitary Neoplasms; Polymerase Chain Reaction; Potassium Chloride; Prolactin; Quinpirole; Rats; Receptors, Dopamine D2; Recombinant Fusion Proteins; Spiperone; Sulpiride; Transfection; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1993 |
Sequestration of the short and long isoforms of dopamine D2 receptors expressed in Chinese hamster ovary cells.
Topics: Animals; Base Sequence; Binding Sites; CHO Cells; Cricetinae; DNA, Complementary; Dopamine; Dopamine Antagonists; Isomerism; Kinetics; Molecular Sequence Data; Receptors, Dopamine D2; Spiperone; Sulpiride; Tritium | 1996 |
Residues in the seventh membrane-spanning segment of the dopamine D2 receptor accessible in the binding-site crevice.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Cysteine; Dopamine Antagonists; Ethyl Methanesulfonate; GTP-Binding Proteins; Humans; Kinetics; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Dopamine D2; Signal Transduction; Spiperone; Sulfhydryl Reagents; Sulpiride | 1996 |
Residues in the fifth membrane-spanning segment of the dopamine D2 receptor exposed in the binding-site crevice.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Resistance; Ethyl Methanesulfonate; Humans; Mesylates; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Receptors, Dopamine D2; Spiperone; Sulpiride; Transfection | 1995 |
Pharmacological characterization and autoradiographic localization of dopamine receptors in the rat adrenal medulla.
Topics: Adrenal Medulla; Animals; Autoradiography; Benzazepines; Butaclamol; Corpus Striatum; Haloperidol; Male; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Sulpiride | 1996 |
The behavioural effects of pramipexole, a novel dopamine receptor agonist.
Topics: Animals; Antiparkinson Agents; Benzazepines; Benzothiazoles; Body Temperature; Catalepsy; Clozapine; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced; Haloperidol; Injections, Subcutaneous; Levodopa; Male; Mice; Motor Activity; Pramipexole; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Spiperone; Stereotyped Behavior; Sulpiride; Thiazoles | 1997 |
Perinatal asphyxia induces long-term changes in dopamine D1, D2, and D3 receptor binding in the rat brain.
Topics: Animals; Apomorphine; Asphyxia Neonatorum; Benzazepines; Brain; Cesarean Section; Dopamine Agonists; Female; Humans; Infant, Newborn; Iodine Radioisotopes; Organ Specificity; Pregnancy; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Spiperone; Sulpiride | 1997 |
Pergolide binds tightly to dopamine D2 short receptors and induces receptor sequestration.
Topics: Animals; COS Cells; Dopamine; Dopamine Agonists; Dopamine Antagonists; Ligands; Pergolide; Receptors, Dopamine D2; Spiperone; Sulpiride | 1997 |
A cluster of aromatic residues in the sixth membrane-spanning segment of the dopamine D2 receptor is accessible in the binding-site crevice.
Topics: Amino Acid Sequence; Amino Acids, Cyclic; Binding Sites; Dopamine Agonists; Dopamine Antagonists; Ethyl Methanesulfonate; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Receptors, Dopamine D2; Spiperone; Sulpiride | 1998 |
The effect of acute kainic acid treatment on dopamine D2 receptors in rat brain.
Topics: Animals; Brain; Iodine Radioisotopes; Isotope Labeling; Kainic Acid; Male; Neurons; Protein Binding; Raclopride; Rats; Rats, Wistar; Receptors, Dopamine D2; Salicylamides; Spiperone; Sulpiride; Tritium | 1998 |
Sequestration of dopamine D2 receptors depends on coexpression of G-protein-coupled receptor kinases 2 or 5.
Topics: Animals; beta-Adrenergic Receptor Kinases; Binding Sites; COS Cells; Cyclic AMP-Dependent Protein Kinases; Dopamine; G-Protein-Coupled Receptor Kinase 2; G-Protein-Coupled Receptor Kinase 5; Gene Expression; Humans; Protein Serine-Threonine Kinases; Receptor Protein-Tyrosine Kinases; Receptors, Dopamine D2; Spiperone; Sulpiride | 1999 |
Dihydroetorphine-induced place preference was mediated by dopamine D1 receptors in rats.
Topics: Animals; Behavior, Animal; Benzazepines; Dopamine Agonists; Etorphine; Haloperidol; Male; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Sulpiride | 1999 |
Dopamine receptor antagonists modulate glucose uptake in rat pheochromocytoma (PC12) cells.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Benzazepines; Biological Transport; Chlorpromazine; Clozapine; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Fluphenazine; Glucose; Haloperidol; PC12 Cells; Pimozide; Rats; Receptors, Dopamine D2; Spiperone; Sulpiride; Tritium | 1999 |
Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity.
Topics: Animals; Cell Membrane; Cerebral Cortex; CHO Cells; Colforsin; Corpus Striatum; Cricetinae; Cyclic AMP; Dimerization; Dopamine D2 Receptor Antagonists; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; Humans; Ligands; Male; Neurons; Pyramidal Cells; Quinpirole; Rats; Receptor Cross-Talk; Receptors, Dopamine D2; Receptors, Somatostatin; Somatostatin; Spiperone; Sulpiride; Transfection | 2000 |
The presence and role of the dopamine DA-2 receptor in the human decidua.
Topics: Decidua; Dopamine; Female; Humans; Pregnancy; Prostaglandins F; Radioligand Assay; Receptors, Dopamine D2; Spiperone; Sulpiride; Tritium | 2000 |
Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation.
Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Bromocriptine; Butaclamol; Chlorpromazine; CHO Cells; Clozapine; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; GTP-Binding Proteins; Haloperidol; Humans; Macromolecular Substances; Mutagenesis, Site-Directed; Phenethylamines; Piperidines; Protein Binding; Protein Conformation; Radioligand Assay; Receptors, Dopamine D2; Recombinant Fusion Proteins; Sodium; Spiperone; Structure-Activity Relationship; Sulpiride; Transfection; Tyramine | 2001 |
Modulation of dopamine uptake in rat nucleus accumbens: effect of specific dopamine receptor antagonists and sigma ligands.
Topics: Animals; Antipsychotic Agents; Carbazoles; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Haloperidol; Ligands; Neurons; Nomifensine; Nucleus Accumbens; Phenazocine; Progesterone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, sigma; Spiperone; Sulpiride; Synaptosomes; Tritium | 2001 |
Pharmacological characterization of the D1- and D2-like dopamine receptors from the brain of the leopard frog, Rana pipiens.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Binding, Competitive; Brain; Radioligand Assay; Rana pipiens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Species Specificity; Spiperone; Sulpiride | 2001 |
(-)S amisulpride binds with high affinity to cloned dopamine D(3) and D(2) receptors.
Topics: Amisulpride; Animals; Benzamides; Binding, Competitive; Cell Line; DNA, Recombinant; Dopamine Antagonists; Dose-Response Relationship, Drug; Humans; Radioligand Assay; Rats; Receptors, Dopamine D2; Receptors, Dopamine D3; Spiperone; Stereoisomerism; Sulpiride; Tritium | 2001 |
Measurement of dopamine D2-like receptors in postmortem CNS and pituitary: differential regional changes in schizophrenia.
Topics: Adult; Aged; Antipsychotic Agents; Autopsy; Autoradiography; Case-Control Studies; Caudate Nucleus; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Pituitary Gland; Putamen; Receptors, Dopamine D2; Schizophrenia; Spiperone; Sulpiride | 2004 |
Chirospecific and subtype selective dopamine receptor binding of heterocyclic methoxynaphthamide analogs.
Topics: Animals; Benzazepines; Binding Sites; CHO Cells; Cricetinae; Heterocyclic Compounds; Humans; Mutagenicity Tests; Naphthalenes; Pyrazoles; Pyrrolidines; Quantitative Structure-Activity Relationship; Rats; Receptors, Dopamine; Sexual Dysfunctions, Psychological; Spiperone; Stereoisomerism; Sulpiride; Swine; Thymidine; Tritium | 2005 |
Structural determinants of pharmacological specificity between D(1) and D(2) dopamine receptors.
Topics: Alternative Splicing; Animals; Benzazepines; Cell Line; Dopamine Antagonists; Models, Molecular; Mutation; Protein Conformation; Raclopride; Radioligand Assay; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Solvents; Spiperone; Sulpiride | 2006 |
Characterization of functional roles of DRY motif in the 2nd intracellular loop of dopamine D2 and D3 receptors.
Topics: Amino Acid Motifs; Apomorphine; Arginine; Aspartic Acid; Cell Line; Cell Membrane; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Humans; Mutation; Protein Conformation; Protein Structure, Tertiary; Protein Transport; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D3; Signal Transduction; Spiperone; Sulpiride; Transfection | 2008 |
Structure-based drug design for dopamine D3 receptor.
Topics: Animals; Combinatorial Chemistry Techniques; Drug Design; Haloperidol; Humans; Indoles; Mice; Models, Molecular; Molecular Structure; Piperazines; Piperidines; Pyrazoles; Pyridines; Receptors, Dopamine D3; Spiperone; Structure-Activity Relationship; Sulpiride; Thiophenes | 2012 |