Compounds > spiperone
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spiperone and serine

spiperone has been researched along with serine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coley, C; Daniell, S; Naylor, LH; Strange, PG; Woodward, R1
Cravchik, A; Gejman, PV; Hietala, J; Någren, K; Pohjalainen, T; Rinne, J; Syvälahti, E1
Sartania, N; Strange, PG1
Einsiedel, J; Gmeiner, P; Hübner, H1
Bordeleau, M; Brooks, KM; Corbett, TJ; de Lannoy, I; Hendrix, JA; Kafka, S; Kamboj, RK; Kapples, KJ; Laws-Ricker, L; Lee, DK; Owolabi, J; Palermo, MG; Rizkalla, G; Shimshock, SJ; Shutske, GM; Tomer, JD; Vargas, HM1

Other Studies

5 other study(ies) available for spiperone and serine

ArticleYear
Investigation of the role of conserved serine residues in the long form of the rat D2 dopamine receptor using site-directed mutagenesis.
    Journal of neurochemistry, 1996, Volume: 66, Issue:1

    Topics: Alanine; Allosteric Regulation; Animals; Cell Line, Transformed; Chlorocebus aethiops; Dopamine Agonists; Dopamine Antagonists; GTP-Binding Proteins; Guanosine Triphosphate; Hydrogen Bonding; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, Dopamine D2; Serine; Spiperone; Structure-Activity Relationship; Transfection

1996
Antagonist binding characteristics of the Ser311-->Cys variant of human dopamine D2 receptor in vivo and in vitro.
    Biochemical and biophysical research communications, 1997, Mar-06, Volume: 232, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; CHO Cells; Cricetinae; Cysteine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Female; Heterozygote; Humans; Male; Middle Aged; Protein Binding; Raclopride; Radioligand Assay; Receptors, Dopamine D2; Salicylamides; Serine; Spiperone

1997
Role of conserved serine residues in the interaction of agonists with D3 dopamine receptors.
    Journal of neurochemistry, 1999, Volume: 72, Issue:6

    Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Binding, Competitive; Cell Line; Conserved Sequence; Dopamine; Dopamine Agonists; Humans; Kidney; Kinetics; Mutagenesis, Site-Directed; Point Mutation; Receptors, Dopamine D2; Receptors, Dopamine D3; Serine; Spiperone; Tetrahydronaphthalenes; Tritium

1999
Benzamide bioisosteres incorporating dihydroheteroazole substructures: EPC synthesis and SAR leading to a selective dopamine D4 receptor partial agonist (FAUC 179).
    Bioorganic & medicinal chemistry letters, 2001, Sep-17, Volume: 11, Issue:18

    Topics: Animals; Biochemistry; Cattle; CHO Cells; Clozapine; Cricetinae; Cysteine; Dopamine Antagonists; Drug Design; Humans; In Vitro Techniques; Indoles; Magnetic Resonance Spectroscopy; Molecular Structure; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D4; Serine; Spiperone; Stereoisomerism; Structure-Activity Relationship; Threonine

2001
Synthesis and structure-activity relationship of the isoindolinyl benzisoxazolpiperidines as potent, selective, and orally active human dopamine D4 receptor antagonists.
    Chembiochem : a European journal of chemical biology, 2002, Oct-04, Volume: 3, Issue:10

    Topics: Administration, Oral; Animals; Apomorphine; Benzyl Compounds; Dizocilpine Maleate; Dopamine D2 Receptor Antagonists; Indoles; Infusions, Parenteral; Isoxazoles; Piperidines; Prazosin; Rats; Receptors, Dopamine D4; Serine; Spiperone; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity

2002