spiperone has been researched along with ritanserin in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.90) | 18.7374 |
| 1990's | 14 (45.16) | 18.2507 |
| 2000's | 12 (38.71) | 29.6817 |
| 2010's | 1 (3.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Janssen, CG; Laduron, PM; Thijssen, JB; Van Dun, J; Wouters, W | 1 |
| Adham, N; Bard, JA; Branchek, TA; Vaysse, P; Weinshank, RL; Zgombick, J | 1 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB | 1 |
| Benhamú, B; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Porras, E; Ramos, JA | 1 |
| Kristiansen, K; Kroeze, WK; Roth, BL; Shapiro, DA | 1 |
| Bach, T; Krobert, KA; Kvingedal, AM; Levy, FO; Syversveen, T | 1 |
| Itoh, H; Muramatsu, I; Taniguchi, T; Yoshio, R | 1 |
| Glennon, RA | 1 |
| Benhamú, B; Campillo, M; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Olivella, M; Pardo, L; Porras, E; Ramos, JA; Soto, LJ | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Bianucci, AM; Calderone, V; Coi, A; Massarelli, I; Testai, L | 1 |
| Cleves, AE; Jain, AN; Kirshner, D; Langham, JJ; Spitzer, R | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Done, CJ; Sharp, T | 1 |
| Aulakh, CS; Hill, JL; Murphy, DL | 1 |
| Ashby, CR; Edwards, E; Wang, RY | 1 |
| Aghajanian, GK; Sheldon, PW | 2 |
| Cowen, PJ; Gartside, SE | 1 |
| Cohen, ML; Kurz, KD; Schenck, KW | 1 |
| Barone, D; Bendotti, C; Caccia, S; Garattini, S; Mennini, T; Samanin, R | 1 |
| Hatano, K; Hatazawa, J; Ido, T; Ishiwata, K; Itoh, M; Kawashima, K | 1 |
| Fornal, CA; Jacobs, BL; Litto, WJ; Marrosu, F; Metzler, CW; Tada, K | 1 |
| Aghajanian, GK; Alreja, M; Garratt, JC | 1 |
| Coulson, A; Grahame-Smith, DG; Leslie, RA; Moorman, JM | 1 |
| al-Tikriti, MS; Baldwin, RM; Charney, DS; Kessler, RM; Kung, HF; Laruelle, M; Malison, RT; Sybirska, E; Zea-Ponce, Y; Zoghbi, SS | 1 |
| Bult, H; Geerts, IS; Herman, AG; Matthys, KE | 1 |
| Appel, JB; Chachich, ME; Lou, A; Pechersky, K; West, WB | 1 |
| Barahona, MV; García-Sacristán, A; Hernández, M; Martínez, AC; Orensanz, LM; Prieto, D; Recio, P; Rivera, L; Simonsen, U | 1 |
| Calama, E; Martín, ML; Morán, A; Ortiz de Urbina, AV; San Román, L | 1 |
1 review(s) available for spiperone and ritanserin
| Article | Year |
|---|---|
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
30 other study(ies) available for spiperone and ritanserin
| Article | Year |
|---|---|
In vitro labeling of serotonin-S2 receptors: synthesis and binding characteristics of [3H]-7-aminoketanserin.
Topics: Animals; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Frontal Lobe; Guinea Pigs; Ketanserin; Kinetics; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1986 |
Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.
Topics: Adenylyl Cyclases; Base Sequence; Cloning, Molecular; DNA Primers; Humans; Molecular Sequence Data; Receptors, Serotonin; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction | 1993 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor.
Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine | 1998 |
First pharmacophoric hypothesis for 5-HT7 antagonism.
Topics: Animals; Cell Membrane; Drug Design; Drug Evaluation, Preclinical; Hypothalamus; Models, Molecular; Rats; Receptors, Serotonin; Reproducibility of Results; Serotonin Antagonists; Structure-Activity Relationship | 2000 |
Differential modes of agonist binding to 5-hydroxytryptamine(2A) serotonin receptors revealed by mutation and molecular modeling of conserved residues in transmembrane region 5.
Topics: Amino Acid Substitution; Animals; Binding, Competitive; Conserved Sequence; COS Cells; DOM 2,5-Dimethoxy-4-Methylamphetamine; Hydrolysis; Membrane Proteins; Models, Molecular; Mutagenesis, Site-Directed; Phosphatidylinositols; Protein Folding; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Signal Transduction; Tryptamines | 2000 |
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution.
Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Brain; Cell Line; Cloning, Organism; Genetic Variation; Humans; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution | 2001 |
Affinity of serotonin receptor antagonists and agonists to recombinant and native alpha1-adrenoceptor subtypes.
Topics: Animals; Aorta, Thoracic; Carotid Arteries; Dogs; Humans; Male; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
Optimization of the pharmacophore model for 5-HT7R antagonism. Design and synthesis of new naphtholactam and naphthosultam derivatives.
Topics: Animals; Binding, Competitive; Computer Simulation; Drug Design; Hypothalamus; In Vitro Techniques; Lactams; Ligands; Male; Models, Molecular; Molecular Conformation; Naphthalenes; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides; Thiazoles | 2003 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation.
Topics: Amino Acid Sequence; Heart; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG | 2008 |
Physical binding pocket induction for affinity prediction.
Topics: Binding Sites; Ligands; Models, Molecular; Neural Networks, Computer; Peptide Fragments; Protein Binding; Receptor, Serotonin, 5-HT1A | 2009 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Evidence that 5-HT2 receptor activation decreases noradrenaline release in rat hippocampus in vivo.
Topics: Amphetamines; Animals; DOM 2,5-Dimethoxy-4-Methylamphetamine; Electrophysiology; Hippocampus; Male; Neurons; Norepinephrine; p-Chloroamphetamine; Quipazine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Receptor Agonists; Spiperone; Sulpiride | 1992 |
Effects of various serotonin receptor subtype-selective antagonists alone and on m-chlorophenylpiperazine-induced neuroendocrine changes in rats.
Topics: Animals; Corticosterone; Ergolines; Male; Metergoline; Mianserin; Neurosecretory Systems; Piperazines; Prolactin; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiperone | 1992 |
Action of serotonin in the medial prefrontal cortex: mediation by serotonin3-like receptors.
Topics: Analysis of Variance; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Frontal Lobe; Indoles; Injections, Intravenous; Iontophoresis; Male; Metergoline; Pindolol; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Spiperone; Tropisetron | 1992 |
Excitatory responses to serotonin (5-HT) in neurons of the rat piriform cortex: evidence for mediation by 5-HT1C receptors in pyramidal cells and 5-HT2 receptors in interneurons.
Topics: Animals; Electrophysiology; Ergolines; Interneurons; Limbic System; Male; Neurons; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Spiperone | 1991 |
Serotonin (5-HT) induces IPSPs in pyramidal layer cells of rat piriform cortex: evidence for the involvement of a 5-HT2-activated interneuron.
Topics: Animals; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; Interneurons; Male; Neural Inhibition; Piperidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin; Spiperone | 1990 |
Mediation of ACTH and prolactin responses to 5-HTP by 5-HT2 receptors.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Animals; Dose-Response Relationship, Drug; Ketanserin; Male; Metergoline; Piperidines; Prolactin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiperone | 1990 |
5-HT2-receptor antagonists: alpha 1- vs. 5-HT2-receptor blocking properties in blood vessels.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Ergolines; Ketanserin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phentolamine; Piperidines; Pyrimidinones; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiperone | 1988 |
Evidence that central 5-HT2 receptors do not play an important role in the anorectic activity of D-fenfluramine in the rat.
Topics: Animals; Appetite Depressants; Brain Chemistry; Eating; Fenfluramine; Histamine H2 Antagonists; Male; Metergoline; Norfenfluramine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Spiperone | 1989 |
D2-dopamine receptor specific brain uptake of carbon-11-labeled YM-09151-2.
Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Carbon Radioisotopes; Cerebellum; Corpus Striatum; Dogs; Male; Piperidines; Radionuclide Imaging; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Ritanserin; Serotonin Antagonists; Spiperone; Sulpiride | 1989 |
Single-unit responses of serotonergic dorsal raphe neurons to 5-HT1A agonist and antagonist drug administration in behaving cats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cats; Depression, Chemical; Dopamine D2 Receptor Antagonists; Female; Haloperidol; Male; Membrane Potentials; Neurons; Premedication; Raphe Nuclei; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone | 1994 |
LSD has high efficacy relative to serotonin in enhancing the cationic current Ih: intracellular studies in rat facial motoneurons.
Topics: Animals; Brain; Electrophysiology; Facial Nerve; In Vitro Techniques; Lysergic Acid Diethylamide; Male; Membrane Potentials; Motor Neurons; Rats; Rats, Sprague-Dawley; Ritanserin; Serotonin; Spiperone | 1993 |
Serotonin2/1C receptor activation causes a localized expression of the immediate-early gene c-fos in rat brain: evidence for involvement of dorsal raphe nucleus projection fibres.
Topics: Amphetamines; Animals; Behavior, Animal; Brain Chemistry; Deoxyglucose; Gene Expression; Genes, fos; Immunohistochemistry; Male; Nerve Fibers; Neural Pathways; Proto-Oncogene Proteins c-fos; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Receptor Agonists; Spiperone | 1993 |
Comparison of three high affinity SPECT radiotracers for the dopamine D2 receptor.
Topics: Animals; Benzamides; Benzofurans; Brain; Contrast Media; Dextroamphetamine; Dopamine Agents; Female; Iodine Radioisotopes; Papio; Pyrrolidines; Raclopride; Receptors, Dopamine D2; Ritanserin; Salicylamides; Serotonin Antagonists; Spiperone; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 1994 |
Involvement of 5-HT1B receptors in collar-induced hypersensitivity to 5-hydroxytryptamine of the rabbit carotid artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Braces; Carotid Arteries; Dose-Response Relationship, Drug; Hypersensitivity; In Vitro Techniques; Ketanserin; Male; Methysergide; Oxadiazoles; Piperazines; Potassium Chloride; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sumatriptan; Tryptamines; Vasoconstriction | 1999 |
Antagonism of a PCP drug discrimination by hallucinogens and related drugs.
Topics: Animals; Brain; Discrimination Learning; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Drug Combinations; Lisuride; Lysergic Acid Diethylamide; Male; N,N-Dimethyltryptamine; Phencyclidine; Rats; Rats, Sprague-Dawley; Ritanserin; Spiperone; Time Factors | 2000 |
Characterization of the 5-hydroxytryptamine receptors mediating contraction in the pig isolated intravesical ureter.
Topics: Animals; Dose-Response Relationship, Drug; Female; Guanethidine; In Vitro Techniques; Male; Muscle Contraction; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin; Spiperone; Swine; Tetrodotoxin; Tryptamines; Ureter; Urinary Bladder; Urothelium | 2003 |
Vasoconstrictor responses to 5-hydroxytryptamine in the autoperfused hindquarters of spontaneously hypertensive rats.
Topics: Animals; Dose-Response Relationship, Drug; Hindlimb; Indoles; Injections, Intra-Arterial; Injections, Intravenous; Male; Perfusion; Piperazines; Prazosin; Pyridines; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT2; Regional Blood Flow; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Spiperone; Thiophenes; Vasoconstriction | 2004 |