spiperone has been researched along with risperidone in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (43.48) | 18.2507 |
| 2000's | 9 (39.13) | 29.6817 |
| 2010's | 4 (17.39) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bervoets, K; Brocco, M; Dacquet, C; Girardon, S; Gobert, A; Millan, MJ; Newman-Tancredi, A; Peglion, JL; Rivet, JM; Vian, J | 1 |
| Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A | 1 |
| Egan, CT; Herrick-Davis, K; Teitler, M | 1 |
| Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L | 1 |
| Grinde, E; Herrick-Davis, K; Teitler, M | 1 |
| Itoh, H; Muramatsu, I; Taniguchi, T; Yoshio, R | 1 |
| Glennon, RA | 1 |
| Brasili, L; Costantino, L; Franchini, S; Gandolfi, F; Leonardi, A; Poggesi, E; Prezzavento, O; Ronsisvalle, G; Sorbi, C; Vittorio, F | 1 |
| Li, MY; Tsai, KC; Xia, L | 1 |
| Cleves, AE; Jain, AN; Kirshner, D; Langham, JJ; Spitzer, R | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, K; Gao, B; Guo, L; Jiang, H; Li, Z; Liu, H; Qian, W; Sun, H; Yang, H; Zhen, X; Zhou, S; Zhou, Y; Zhu, L | 1 |
| Chen, Y; Liu, BF; Liu, S; Liu, X; Qiu, Y; Wang, S; Xu, X; Yu, M; Zhang, G; Zhang, T; Zhao, S | 1 |
| Cao, X; Chen, Y; Liu, BF; Liu, X; Qiu, Y; Xu, X; Yu, M; Zhang, G; Zhang, L; Zhang, Y | 1 |
| Gommeren, W; Janssen, PA; Janssen, PM; Leysen, JE; Pauwels, PJ; Wynants, J | 1 |
| Assié, MB; Koek, W; Sleight, AJ | 1 |
| Burgess, LH; Meltzer, HY; Roth, BL; Sibley, DR; Tandra, S | 1 |
| Fukuda, T; Futamura, T; Haga, K; Ohashi, Y; Takahashi, Y; Yano, K | 1 |
| Aghajanian, GK; Marek, GJ | 1 |
| Eriksson, B; Farde, L; Halldin, C; Nyberg, S; Oxenstierna, G | 1 |
| Sabel, BA; Schroeder, H; Schroeder, U; Schwegler, H | 1 |
| Chagkutip, J; Govitrapong, P; Srikiatkhachorn, A; Turakitwanakan, W | 1 |
| Huang, XF; Zavitsanou, K | 1 |
1 review(s) available for spiperone and risperidone
| Article | Year |
|---|---|
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
1 trial(s) available for spiperone and risperidone
| Article | Year |
|---|---|
Suggested minimal effective dose of risperidone based on PET-measured D2 and 5-HT2A receptor occupancy in schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Brain; Carbon Radioisotopes; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorine Radioisotopes; Humans; Male; Psychiatric Status Rating Scales; Raclopride; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Salicylamides; Schizophrenia; Schizophrenic Psychology; Spiperone; Tomography, Emission-Computed; Treatment Outcome | 1999 |
21 other study(ies) available for spiperone and risperidone
| Article | Year |
|---|---|
Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: 1. Activation of postsynaptic D3 receptors mediates hypothermia, whereas blockade of D2 receptors elicits prolactin
Topics: 2-Naphthylamine; Animals; Body Temperature Regulation; Catalepsy; CHO Cells; Cricetinae; Dopamine Antagonists; Furans; Humans; Male; Prolactin; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Dopamine D2; Recombinant Proteins; Stereoisomerism | 1995 |
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin | 1994 |
Creation of a constitutively activated state of the 5-hydroxytryptamine2A receptor by site-directed mutagenesis: inverse agonist activity of antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; COS Cells; Mutagenesis, Site-Directed; Phosphatidylinositols; Protein Conformation; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship | 1998 |
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes | 1998 |
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors.
Topics: Animals; Antipsychotic Agents; COS Cells; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Receptor Agonists | 2000 |
Affinity of serotonin receptor antagonists and agonists to recombinant and native alpha1-adrenoceptor subtypes.
Topics: Animals; Aorta, Thoracic; Carotid Arteries; Dogs; Humans; Male; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
Synthesis and structure-activity relationships of 1-aralkyl-4-benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent sigma ligands.
Topics: Animals; Binding Sites; Biochemistry; Cells, Cultured; Drug Evaluation, Preclinical; Guinea Pigs; Humans; Inhibitory Concentration 50; Ligands; Piperazines; Piperidines; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma; Serotonin 5-HT1 Receptor Agonists; Sigma-1 Receptor; Structure-Activity Relationship | 2005 |
Pharmacophore identification of alpha(1A)-adrenoceptor antagonists.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Drug Evaluation, Preclinical; Expert Systems; Humans; Models, Molecular; Receptors, Adrenergic, alpha-1; Software; Structure-Activity Relationship | 2005 |
Physical binding pocket induction for affinity prediction.
Topics: Binding Sites; Ligands; Models, Molecular; Neural Networks, Computer; Peptide Fragments; Protein Binding; Receptor, Serotonin, 5-HT1A | 2009 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile.
Topics: Animals; Antipsychotic Agents; Berberine; Berberine Alkaloids; CHO Cells; Cricetinae; Cricetulus; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Microwaves; Motor Activity; Protein Binding; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D1; Receptors, Dopamine D2; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship | 2013 |
Synthesis and biological investigation of coumarin piperazine (piperidine) derivatives as potential multireceptor atypical antipsychotics.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Biological Availability; Coumarins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; In Vitro Techniques; Isoxazoles; Lethal Dose 50; Mice; Motor Activity; Prolactin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Dopamine D3; Structure-Activity Relationship; Weight Gain | 2013 |
Synthesis and Biological Evaluation of Fused Tricyclic Heterocycle Piperazine (Piperidine) Derivatives As Potential Multireceptor Atypical Antipsychotics.
Topics: Animals; Antipsychotic Agents; Body Weight; Chemistry Techniques, Synthetic; Drug Design; Ether-A-Go-Go Potassium Channels; Heterocyclic Compounds; Memory; Mice; Piperazine; Rats; Schizophrenia; Structure-Activity Relationship; Tissue Distribution | 2018 |
In vitro and in vivo receptor binding and effects on monoamine turnover in rat brain regions of the novel antipsychotics risperidone and ocaperidone.
Topics: Animals; Antipsychotic Agents; Biogenic Monoamines; Brain; Female; Haloperidol; In Vitro Techniques; Isoxazoles; Male; Neurotransmitter Agents; Piperidines; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Risperidone; Spiperone; Tissue Distribution | 1992 |
Biphasic displacement of [3H]YM-09151-2 binding in the rat brain by thioridazine, risperidone and clozapine, but not by other antipsychotics.
Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Clozapine; Corpus Striatum; Dopamine D2 Receptor Antagonists; In Vitro Techniques; Isoxazoles; Male; Olfactory Pathways; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Risperidone; Spiperone; Thioridazine | 1993 |
D4 dopamine receptor binding affinity does not distinguish between typical and atypical antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Clozapine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Spiperone | 1995 |
[The affinities of mosapramine for the dopamine receptor subtypes in human cell lines expressing D2, D3 and D4 receptors].
Topics: Antipsychotic Agents; Benzazepines; Cell Line; Clozapine; Haloperidol; Humans; Raclopride; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Dopamine D5; Risperidone; Salicylamides; Spiperone | 1996 |
Alpha 1B-adrenoceptor-mediated excitation of piriform cortical interneurons.
Topics: Action Potentials; Adrenergic alpha-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dioxanes; In Vitro Techniques; Interneurons; Male; Norepinephrine; Oxathiins; Phentolamine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Risperidone; Spiperone | 1996 |
Neuroleptics ameliorate phencyclidine-induced impairments of short-term memory.
Topics: Animals; Antipsychotic Agents; Benzazepines; Brain; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Interneurons; Male; Memory Disorders; Memory, Short-Term; Phencyclidine; Rats; Risperidone; Schizophrenia; Spiperone | 2000 |
Platelet 5-HT(2A) receptors in schizophrenic patients with and without neuroleptic treatment.
Topics: Adult; Antipsychotic Agents; Blood Platelets; Case-Control Studies; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Flupenthixol; Humans; Ketanserin; Male; Phenothiazines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Risperidone; Schizophrenia; Serotonin Antagonists; Spiperone | 2000 |
Decreased [(3)H]spiperone binding in the anterior cingulate cortex of schizophrenia patients: an autoradiographic study.
Topics: Adult; Aged; Antipsychotic Agents; Binding Sites; Binding, Competitive; Butaclamol; Down-Regulation; Gyrus Cinguli; Haloperidol; Humans; Mianserin; Middle Aged; Neurons; Neurotransmitter Agents; Radioligand Assay; Receptors, Neurotransmitter; Risperidone; Schizophrenia; Spiperone; Tritium | 2002 |