Compounds > spiperone
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spiperone and pyrroles

spiperone has been researched along with pyrroles in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's3 (30.00)18.2507
2000's5 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kruse, CG; Tulp, MT; van der Heyden, JA; van Hes, R; van Wijngaarden, I1
Kruse, CG; Tulp, MT; van der Heyden, JA; van Wijngaarden, I1
Bobirnac, I; Bruinvels, AT; Danzeisen, M; Gazi, L; Geisse, S; Hoyer, D; Schoeffter, P; Schüpbach, E; Sommer, B; Tricklebank, M1
Bobirnac, I; Danzeisen, M; Gazi, L; Hoyer, D; Langenegger, D; Schoeffter, P; Schüpbach, E; Sommer, B; Tricklebank, M1
Gmeiner, P; Haubmann, C; Hübner, H1
Cussac, D; Millan, MJ; Newman-Tancredi, A; Sezgin, L2
Chapman, KL; Hutson, PH; Marston, D; Patel, S; Ragan, CI1
Chen, S; Floresca, CZ; Kortagere, S; Schetz, JA1
Brioni, JD; Chang, R; Cowart, MD; Donnelly-Roberts, DL; Hsieh, GC; Marsh, K; Miller, L; Miller, TR; Moreland, RB; Nakane, M; Namovic, MT; Stewart, AO; Terranova, MA; Uchic, ME; Wetter, JM1

Other Studies

10 other study(ies) available for spiperone and pyrroles

ArticleYear
2-Phenylpyrroles as conformationally restricted benzamide analogues. A new class of potential antipsychotics. 1.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:11

    Topics: Animals; Antipsychotic Agents; Benzamides; Male; Mice; Molecular Conformation; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Structure-Activity Relationship

1987
2-Phenylpyrroles as conformationally restricted benzamide analogues. A new class of potential antipsychotics. 2.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:10

    Topics: Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Benzamides; Chemical Phenomena; Chemistry, Physical; Conditioning, Classical; Corpus Striatum; Dioxanes; Mice; Pyrroles; Rats; Spiperone

1988
The agonist activities of the putative antipsychotic agents, L-745,870 and U-101958 in HEK293 cells expressing the human dopamine D4.4 receptor.
    British journal of pharmacology, 1998, Volume: 124, Issue:5

    Topics: Aminopyridines; Antipsychotic Agents; Cell Line; Clozapine; Colforsin; Cyclic AMP; Dopamine; Dopamine Agonists; Dopamine Antagonists; Humans; Kidney; Piperidines; Pyridines; Pyrroles; Raclopride; Receptors, Dopamine D2; Receptors, Dopamine D4; Recombinant Proteins; Salicylamides; Spiperone

1998
Receptor density as a factor governing the efficacy of the dopamine D4 receptor ligands, L-745,870 and U-101958 at human recombinant D4.4 receptors expressed in CHO cells.
    British journal of pharmacology, 1999, Volume: 128, Issue:3

    Topics: Aminopyridines; Animals; Butyrates; CHO Cells; Cricetinae; Cyclic AMP; Dopamine Agents; Humans; Ligands; Piperidines; Pyridines; Pyrroles; Radioligand Assay; Receptors, Dopamine D2; Receptors, Dopamine D4; Recombinant Proteins; Spiperone

1999
Piperidinylpyrroles: design, synthesis and binding properties of novel and selective dopamine D4 receptor ligands.
    Bioorganic & medicinal chemistry letters, 1999, Nov-01, Volume: 9, Issue:21

    Topics: Animals; Binding, Competitive; Cattle; Dopamine Antagonists; Drug Design; Humans; Ligands; Molecular Structure; Protein Binding; Pyrroles; Receptors, Dopamine D2; Receptors, Dopamine D4; Spiperone

1999
The novel antagonist, S33084, and GR218,231 interact selectively with cloned and native, rat dopamine D(3) receptors as compared with native, rat dopamine D(2) receptors.
    European journal of pharmacology, 2000, Apr-07, Volume: 394, Issue:1

    Topics: Animals; Benzopyrans; Binding, Competitive; CHO Cells; Cricetinae; Dopamine Antagonists; Olfactory Pathways; Oxazines; Pyrroles; Rats; Receptors, Dopamine D2; Receptors, Dopamine D3; Recombinant Proteins; Spiperone; Sulfones; Tetrahydronaphthalenes

2000
[3H]S33084: a novel, selective and potent radioligand at cloned, human dopamine D3 receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:5

    Topics: Animals; Benzopyrans; Binding, Competitive; Cells, Cultured; CHO Cells; Cricetinae; Dopamine Antagonists; Humans; Pyrroles; Radioligand Assay; Receptors, Dopamine D2; Receptors, Dopamine D3; Recombinant Proteins; Spiperone; Transfection; Tritium

2000
Pharmacological and functional characterisation of dopamine D4 receptors in the rat retina.
    Neuropharmacology, 2003, Volume: 44, Issue:8

    Topics: Animals; Binding Sites; Cyclic AMP; Darkness; Dopamine Agonists; Dopamine Antagonists; In Vitro Techniques; Indoles; Male; Piperidines; Pyridines; Pyrroles; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D4; Retina; Spiperone

2003
Reciprocal mutations in TM2/TM3 in a D2 dopamine receptor background confirms the importance of this microdomain as a selective determinant of para-halogenated 1,4-disubstituted aromatic piperazines.
    Archiv der Pharmazie, 2005, Volume: 338, Issue:5-6

    Topics: Animals; Chemistry, Pharmaceutical; Chlorocebus aethiops; COS Cells; Membrane Microdomains; Membrane Transport Proteins; Mutation; Piperazine; Piperazines; Pyrazoles; Pyridines; Pyrroles; Rats; Receptors, Dopamine D2; Spiperone; Tritium

2005
2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist.
    Neuropharmacology, 2005, Volume: 49, Issue:1

    Topics: Animals; Benzamides; Benzimidazoles; Binding, Competitive; Calcium; Cell Line; Clozapine; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Europium; Fluorometry; GABA Antagonists; Guanosine Triphosphate; Humans; Male; Penile Erection; Piperazines; Pyridines; Pyrroles; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Spiperone; Time Factors; Tritium

2005