Page last updated: 2024-08-16

spiperone and propranolol

spiperone has been researched along with propranolol in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199015 (53.57)18.7374
1990's9 (32.14)18.2507
2000's1 (3.57)29.6817
2010's3 (10.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Billings, JJ; Chumpradit, S; Kung, HF; Kung, MP1
Billings, J; Kung, HF; Kung, MP; Murphy, RA1
Guo, YZ; Kasliwal, R; Kung, HF; Kung, MP; Mach, RH; Pan, SG1
Andrews, PR; Craik, DJ; Martin, JL1
Billings, J; Chumpradit, S; Kung, HF; Kung, MP; Mach, R1
Kung, HF; Kung, MP; Zhuang, ZP1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Brouillette, WJ; Brown, GB; Zha, C1
Artursson, P; Mateus, A; Matsson, P1
Giachetti, A; Hefco, E; Jameson, HE; Krulich, L; Marchlewska-Koj, A1
Kuruma, I; Naitoh, F; Nakajima, T1
Erickson, CK; Matchett, JA1
Haj-Dahmane, S; Hamon, M; Lanfumey, L1
Davies, M; Fletcher, PJ1
Blier, P; Chaput, Y; de Montigny, C; Steinberg, S1
Jenner, P; Marsden, CD; Stewart, BR1
Horisaka, K; Sugimoto, Y; Yamada, J1
Murakami, H; Sano, M; Tsukimura, T; Yamazaki, A1
Crews, FT; Scott, JA1
Barone, P; Fayolle, C; Fillion, G; Fillion, MP; Oudar, P; Rousselle, JC1
Speiser, Z; Weinstock, M1
Charlton, KG; Clarke, DE; Hamed, AT; Johnson, TD1
Bakunzi, FR; Eyre, P1
Connor, TM; Fregly, MJ; Kikta, DC; Threatte, RM1
Abdel-Fattah, AF; el-Hady, KA; Matsumoto, K; Watanabe, H1
Gajendiran, M; Ganguly, DK; Seth, P1
Fox, K; Lam, P; Ling, V; Shapiro, AB1
Lai, WS; Liao, RM; Lin, JY1

Other Studies

28 other study(ies) available for spiperone and propranolol

ArticleYear
Synthesis and resolution of (+-)-7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro- 1H-3- benzazepine (TISCH): a high affinity and selective iodinated ligand for CNS D1 dopamine receptor.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Animals; Benzazepines; Binding, Competitive; Brain; Cell Membrane; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Iodine Radioisotopes; Isotope Labeling; Male; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Tissue Distribution

1991
Synthesis and characterization of iodobenzamide analogues: potential D-2 dopamine receptor imaging agents.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: Animals; Benzofurans; Binding, Competitive; Chemical Phenomena; Chemistry; Corpus Striatum; Iodine Radioisotopes; Isotope Labeling; Male; Molecular Structure; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Tissue Distribution

1990
Dopamine D-2 receptor imaging radiopharmaceuticals: synthesis, radiolabeling, and in vitro binding of (R)-(+)- and (S)-(-)-3-iodo-2-hydroxy-6-methoxy-N- [(1-ethyl-2-pyrrolidinyl)methyl]benzamide.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:5

    Topics: Animals; Benzamides; Chemical Phenomena; Chemistry; Corpus Striatum; In Vitro Techniques; Iodine Radioisotopes; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship

1988
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Fluorinated and iodinated dopamine agents: D2 imaging agents for PET and SPECT.
    Journal of medicinal chemistry, 1993, Jan-22, Volume: 36, Issue:2

    Topics: Animals; Benzamides; Dopamine Agents; Dopamine D2 Receptor Antagonists; Fluorine Radioisotopes; Iodine Radioisotopes; Macaca fascicularis; Male; Pyrrolidines; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

1993
Synthesis of (R,S)-trans-8-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)amino]tetral in (trans-8-OH-PIPAT): a new 5-HT1A receptor ligand.
    Journal of medicinal chemistry, 1993, Oct-15, Volume: 36, Issue:21

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Iodine Radioisotopes; Ligands; Rats; Receptors, Serotonin; Stereoisomerism; Tetrahydronaphthalenes; Tritium

1993
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
    Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1

    Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels

2014
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
On the role of the central noradrenergic and dopaminergic systems in the regulation of TSH secretion in the rat.
    Endocrinology, 1977, Volume: 100, Issue:2

    Topics: Animals; Apomorphine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Clonidine; Ditiocarb; Dopamine; Kinetics; Male; Methyltyrosines; Norepinephrine; Phenoxybenzamine; Phentolamine; Pituitary Gland; Propranolol; Rats; Spiperone; Stress, Physiological; Thyrotropin; Thyrotropin-Releasing Hormone

1977
Dopamine-sensitive adenylate cyclase in the rat kidney particulate preparation.
    European journal of pharmacology, 1977, Jan-21, Volume: 41, Issue:2

    Topics: Adenylyl Cyclases; Animals; Catecholamines; Cyclic AMP; Dopamine; Dopamine Antagonists; Drug Interactions; In Vitro Techniques; Kidney; Male; Phentolamine; Propranolol; Rats; Spiperone; Stimulation, Chemical; Theophylline

1977
Alteration of ethanol-induced changes in locomotor activity by adrenergic blockers in mice.
    Psychopharmacology, 1977, Apr-29, Volume: 52, Issue:2

    Topics: Animals; Drug Interactions; Ethanol; Female; Mice; Mice, Inbred ICR; Motor Activity; Phentolamine; Propranolol; Spiperone; Sympatholytics; Time Factors

1977
K+ channel and 5-hydroxytryptamine1A autoreceptor interactions in the rat dorsal raphe nucleus: an in vitro electrophysiological study.
    Neuroscience, 1991, Volume: 41, Issue:2-3

    Topics: 4-Aminopyridine; Animals; Anti-Anxiety Agents; Apamin; Barium; Charybdotoxin; Electrophysiology; Evoked Potentials; Male; Neurons; Phenylephrine; Potassium Channels; Propranolol; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Scorpion Venoms; Spiperone

1991
A pharmacological analysis of the eating response induced by 8-OH-DPAT injected into the dorsal raphé nucleus reveals the involvement of a dopaminergic mechanism.
    Psychopharmacology, 1990, Volume: 100, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dopamine; Drug Interactions; Eating; Haloperidol; Injections; Male; Metergoline; Naphthalenes; Propranolol; Raphe Nuclei; Rats; Rats, Inbred Strains; Spiperone; Tetrahydronaphthalenes

1990
Electrophysiological assessment of putative antagonists of 5-hydroxytryptamine receptors: a single-cell study in the rat dorsal raphe nucleus.
    Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:2

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electrophysiology; Lysergic Acid Diethylamide; Male; Methiothepin; Neurons; Propranolol; Quinazolines; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin Antagonists; Spiperone; Tetrahydronaphthalenes

1989
Induction of purposeless chewing behaviour in rats by 5-HT agonist drugs.
    European journal of pharmacology, 1989, Mar-14, Volume: 162, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Male; Methiothepin; Methoxydimethyltryptamines; Mianserin; Parasympatholytics; Piperazines; Propranolol; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes

1989
The evidence for the involvement of the 5-HT1A receptor in 5-HT syndrome induced in mice by tryptamine.
    Japanese journal of pharmacology, 1989, Volume: 51, Issue:3

    Topics: Animals; Behavior, Animal; Haloperidol; Ketanserin; Male; Methysergide; Mice; Mice, Inbred DBA; Propranolol; Receptors, Serotonin; Serotonin; Spiperone; Tryptamines

1989
The relaxation induced by indole and nonindole 5-HT agonists in the molluscan smooth muscle.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1988, Volume: 90, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bivalvia; Cyclic AMP; In Vitro Techniques; Indoles; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Pindolol; Propranolol; Proteins; Serotonin; Spiperone; Tetrahydronaphthalenes

1988
Down-regulation of serotonin2, but not of beta-adrenergic receptors during chronic treatment with amitriptyline is independent of stimulation of serotonin2 and beta-adrenergic receptors.
    Neuropharmacology, 1986, Volume: 25, Issue:12

    Topics: Amitriptyline; Animals; Cerebral Cortex; Dihydroalprenolol; Hippocampus; In Vitro Techniques; Male; Piperazines; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Serotonin; Reserpine; Serotonin; Spiperone; Triazoles

1986
5-Hydroxytryptamine stimulates two distinct adenylate cyclase activities in rat brain: high-affinity activation is related to a 5-HT1 subtype different from 5-HT1A, 5-HT1B, and 5-HT1C.
    Fundamental & clinical pharmacology, 1988, Volume: 2, Issue:3

    Topics: Adenylyl Cyclases; Animals; Brain; In Vitro Techniques; Male; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone

1988
Modification by propranolol and related compounds of motor activity and stereotype behaviour induced in the rat by amphetamine.
    European journal of pharmacology, 1974, Volume: 25, Issue:1

    Topics: Amphetamine; Animals; Behavior; Chlorpromazine; Dose-Response Relationship, Drug; Humans; Male; Motor Activity; Moxisylyte; Norepinephrine; Oxprenolol; Practolol; Propranolol; Rats; Spiperone; Stereotyped Behavior; Stimulation, Chemical

1974
Cardiovascular actions of kynuramine and 5-hydroxykynuramine in pithed rats.
    Journal of neural transmission, 1983, Volume: 57, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Brain; Cerebral Cortex; Decerebrate State; Heart Rate; Kynuramine; Male; Phentolamine; Phenylephrine; Propiophenones; Propranolol; Rats; Receptors, Adrenergic, alpha; Spiperone; Yohimbine

1983
Responses of pulmonary vasculature of cattle to dopamine and apomorphine.
    Journal of veterinary pharmacology and therapeutics, 1983, Volume: 6, Issue:3

    Topics: Animals; Apomorphine; Cattle; Dopamine; Dose-Response Relationship, Drug; In Vitro Techniques; Propranolol; Pulmonary Artery; Receptors, Dopamine; Spiperone; Vasoconstriction; Vasodilation

1983
L-5-Hydroxytryptophan-induced drinking in rats: possible mechanisms for induction.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 14, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Captopril; Clonidine; Drinking; Drug Interactions; Female; Haloperidol; Propranolol; Rats; Spiperone; Stimulation, Chemical

1981
5-HT1A and 5-HT2 receptors mediate hypo- and hyperthermic effects of tryptophan in pargyline-pretreated rats.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Body Temperature; Dopamine Antagonists; Fenclonine; Ketanserin; Male; Monoamine Oxidase Inhibitors; Pargyline; Pindolol; Propranolol; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Spiperone; Tryptophan

1995
Desensitization of spinal 5-HT1A receptors to 8-OH-DPAT: an in vivo spinal reflex study.
    Neuroreport, 1997, Jul-28, Volume: 8, Issue:11

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Male; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex; Serotonin Antagonists; Spinal Cord; Spiperone; Synapses; Time Factors

1997
Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone. Evidence for a third drug-binding site.
    European journal of biochemistry, 1999, Volume: 259, Issue:3

    Topics: Allosteric Site; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Binding Sites; Biological Transport; Cell Membrane; CHO Cells; Cricetinae; Fluorescent Dyes; Flupenthixol; Haloperidol; Molecular Structure; Prazosin; Progesterone; Propranolol; Protein Binding; Rhodamine 123; Spiperone

1999
The role of catecholamines in retention performance of a partially baited radial eight-arm maze for rats.
    The Chinese journal of physiology, 2002, Dec-31, Volume: 45, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Benzazepines; Dopamine; Dopamine Antagonists; Haloperidol; Male; Maze Learning; Memory; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Wistar; Space Perception; Spiperone; Yohimbine

2002