spiperone has been researched along with prazosin in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (51.61) | 18.7374 |
| 1990's | 20 (32.26) | 18.2507 |
| 2000's | 7 (11.29) | 29.6817 |
| 2010's | 3 (4.84) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Dannals, RF; Frost, JJ; Ravert, HT; Wagner, HN; Wilson, AA | 1 |
| Janssen, CG; Laduron, PM; Thijssen, JB; Van Dun, J; Wouters, W | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Bondinell, WE; Hieble, JP; Ruffolo, RR | 1 |
| Crucianelli, M; Giardinà, D; Leonardi, A; Melchiorre, C; Poggesi, E; Romanelli, R | 1 |
| Pedretti, A; Testa, B; Villa, L; Vistoli, G | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Hyttel, J; Nielsen, JB; Nowak, G | 1 |
| Kojima, C; Satoh, M; Takayanagi, I | 1 |
| Barker, EL; Burris, KD; Sanders-Bush, E | 1 |
| Ebadi, M; Happe, HK; Murrin, LC; Simonneaux, V | 1 |
| Ramage, AG | 1 |
| Singer, EA; Valenta, B | 1 |
| Burki, HR | 1 |
| Friedman, E; Gillis, RA; Hamosh, P; Kellar, KJ; Mandal, AK; Pineo, SV | 1 |
| Frenken, M | 1 |
| Pan, ZZ; Williams, JT | 1 |
| Fujiwara, M; Nishikawa, H; Taniguchi, T; Yokotani, K | 1 |
| Bowersox, SS; Ciaranello, RD; Dement, WC; Faull, KF; Maddaluno, JF; Zeller-DeAmicis, L | 1 |
| Gallager, D; Goldman-Rakic, PS; Rakic, P | 1 |
| Babb, S; Baldessarini, RJ; Bird, ED; Campbell, A; Cohen, BM; Froimowitz, M; Hrbek, C; Kula, N; Svendsen, CN; Teicher, MH | 1 |
| Andorn, AC | 1 |
| Greiner, HE; Haase, A; Klockow, M; Schmitges, CJ; Seyfried, C | 1 |
| Baldwin, JJ; Clineschmidt, BV; Huff, JR; Lotti, VJ; Pettibone, DJ; Randall, WC; Vacca, J; Young, SD | 1 |
| Broekkamp, CL; de Boer, T; de Graaf, JS; de Vos, CJ; Gower, A; Rae, D; Van Delft, AM | 1 |
| Forler, C; Fozard, JR; Middlemiss, DN; Tricklebank, MD | 1 |
| Cornett, LE; Light, KE; Norris, JS | 1 |
| Arbilla, S; Bartholini, G; Claustre, Y; Dedek, J; Dennis, T; Langer, SZ; Lloyd, KG; Scatton, B; Zivkovic, B | 1 |
| de Boer, TH; de Vos, CJ; Maura, G; Pinder, RM; Raiteri, M; Wieringa, J | 1 |
| Broadhurst, AM; Wyllie, MG | 1 |
| Nelson, A; Richelson, E | 1 |
| Costall, B; Lim, SK; Naylor, RJ | 1 |
| Bischoff, S; Ortmann, R; Waldmeier, PC | 1 |
| Barbaz, B; Bernard, P; Braunwalder, A; Kim, HS; Liebman, JM; Lovell, RA; Robson, RD; Stone, G; Wasley, JW; Welch, J | 1 |
| Bradbury, AJ; Costall, B; Naylor, RJ; Neumeyer, JL | 1 |
| Antkiewicz-Michaluk, L; Rokosz-Pelc, A; Vetulani, J | 1 |
| Arnt, J; Hyttel, J; Larsen, JJ | 1 |
| Finch, CE; Marcusson, JO; Morgan, DG | 1 |
| Arnt, J; Hyttel, J; Overø, KF | 1 |
| Bhatnagar, RK; Cannon, JG; Chatterjee, TK; Long, JP | 1 |
| DeGroff, V; Fishman, J; McEwen, BS; Paden, CM; Snyder, L | 1 |
| Dekermendjian, K; Nielsen, M; Shen, XL; Witt, MR | 1 |
| Guarneri, L; Leonardi, A; Poggesi, E; Simonazzi, I; Taddei, C; Testa, R | 1 |
| Lidow, MS; Rakic, P | 1 |
| Ageel, AM; Alhaider, AA; Ginawi, OT | 1 |
| Docherty, JR; Kearns, S; O'Rourke, M | 1 |
| Aghajanian, GK; Marek, GJ | 1 |
| Kadavil, EA; Oriowo, MA; Yousif, M | 1 |
| Foster, HE; Latifpour, J; Nishi, K; Saito, M; Weiss, RM; Yoshida, M | 1 |
| Aloyo, VJ; Harvey, JA; Hoffman, ME; Salt, GL | 1 |
| Amobi, N; Coker, C; Guillebaud, J; Mulvin, D; Smith, IC | 1 |
| Fox, K; Lam, P; Ling, V; Shapiro, AB | 1 |
| Berkowitz, DE; Booth, JV; Cozart, KL; D'Amico, EB; El-Moalem, H; Funk, BL; Marucci, L; Page, SO; Richardson, CD; Rudner, XL; Schwinn, DA; Winters, B | 1 |
| Sasa, M; Tanimitsu, N; Tsuru, H; Yajin, K | 1 |
| Froudakis, GE; Katerinopoulos, HE; Tagmatarchis, N; Thermos, K | 1 |
| Bordeleau, M; Brooks, KM; Corbett, TJ; de Lannoy, I; Hendrix, JA; Kafka, S; Kamboj, RK; Kapples, KJ; Laws-Ricker, L; Lee, DK; Owolabi, J; Palermo, MG; Rizkalla, G; Shimshock, SJ; Shutske, GM; Tomer, JD; Vargas, HM | 1 |
| Lai, WS; Liao, RM; Lin, JY | 1 |
| Calama, E; Martín, ML; Morán, A; Ortiz de Urbina, AV; San Román, L | 1 |
| Avellar, MC; Caricati-Neto, A; Jurkiewicz, A; Jurkiewicz, NH; Reuter, HR; Verde, LF | 1 |
1 review(s) available for spiperone and prazosin
| Article | Year |
|---|---|
Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification.
Topics: Animals; Humans; Molecular Biology; Molecular Structure; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1995 |
61 other study(ies) available for spiperone and prazosin
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Synthesis and biological evaluation of [125I]- and [123I]-4-iododexetimide, a potent muscarinic cholinergic receptor antagonist.
Topics: Animals; Dexetimide; Iodine Radioisotopes; Isotope Labeling; Male; Mice; Parasympatholytics; Piperidines; Receptors, Muscarinic; Tomography, Emission-Computed | 1989 |
In vitro labeling of serotonin-S2 receptors: synthesis and binding characteristics of [3H]-7-aminoketanserin.
Topics: Animals; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Frontal Lobe; Guinea Pigs; Ketanserin; Kinetics; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1986 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Synthesis and biological profile of the enantiomers of [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-cis-octahydroquinoxalin- 1-yl]furan-2-ylmethanone (cyclazosin), a potent competitive alpha 1B- adrenoceptor antagonist.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Cattle; Cerebral Cortex; CHO Cells; COS Cells; Cricetinae; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Quinazolines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Stereoisomerism | 1996 |
Range and sensitivity as descriptors of molecular property spaces in dynamic QSAR analyses.
Topics: Chemical Phenomena; Chemistry, Physical; Ligands; Models, Molecular; Molecular Conformation; Monte Carlo Method; Quantitative Structure-Activity Relationship; Receptors, Adrenergic, alpha-1; Solvents | 2005 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
The acute effect of sertindole on brain 5-HT2, D2 and alpha 1 receptors (ex vivo radioreceptor binding studies).
Topics: Animals; Brain Chemistry; Dose-Response Relationship, Drug; Imidazoles; Indoles; Ketanserin; Male; Prazosin; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin; Spiperone | 1992 |
Characterization of alpha 1-adrenoceptor subtypes labeled by [3H]prazosin in single cells prepared from rabbit thoracic aorta.
Topics: Animals; Aorta, Thoracic; Binding Sites; Calcium; Clonidine; Dioxanes; In Vitro Techniques; Methoxamine; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Spiperone | 1992 |
Phosphoinositide hydrolysis linked 5-HT2 receptors in fibroblasts from choroid plexus.
Topics: Animals; Cells, Cultured; Choroid Plexus; DOM 2,5-Dimethoxy-4-Methylamphetamine; Fibroblasts; Haloperidol; Hydrolysis; Inositol Phosphates; Ketanserin; Lysergic Acid Diethylamide; Male; Mianserin; Phosphatidylinositols; Prazosin; Rabbits; Receptors, Serotonin; Serotonin; Spiperone | 1991 |
Autoradiographic localization of dopaminergic and noradrenergic receptors in the bovine pineal gland.
Topics: Animals; Autoradiography; Benzazepines; Cattle; Iodine Radioisotopes; Organ Specificity; Pindolol; Pituitary Gland; Prazosin; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Tritium | 1991 |
The mechanism of the sympathoinhibitory action of urapidil: role of 5-HT1A receptors.
Topics: Anesthesia; Animals; Blood Pressure; Cats; Clonidine; Heart; Heart Rate; Kidney; Male; Piperazines; Prazosin; Receptors, Serotonin; Regional Blood Flow; Spiperone; Splanchnic Nerves; Sympatholytics | 1991 |
Hypotensive effects of 8-hydroxy-2-(di-n-propylamino)tetralin and 5-methylurapidil following stereotaxic microinjection into the ventral medulla of the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Blood Pressure; Dioxanes; Dopamine Antagonists; Heart Rate; Male; Medulla Oblongata; Microinjections; Naphthalenes; Piperazines; Prazosin; Rats; Rats, Inbred Strains; Spiperone; Spiro Compounds; Stereotaxic Techniques; Tetrahydronaphthalenes | 1990 |
Binding of psychoactive drugs to rat brain amine receptors, measured ex vivo, and their effects on the metabolism of biogenic amines.
Topics: Animals; Biogenic Amines; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Methoxyhydroxyphenylglycol; Prazosin; Psychotropic Drugs; Rats; Rats, Inbred Strains; Receptors, Drug; Spiperone | 1986 |
Importance of central nervous system serotonin-1A receptors for mediating the hypotensive effect of urapidil.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antihypertensive Agents; Blood Pressure; Cats; Heart Rate; Medulla Oblongata; Piperazines; Prazosin; Receptors, Serotonin; Respiration; Spiperone; Tetrahydronaphthalenes | 1989 |
Evidence for two populations of 5-hydroxytryptamine receptors in dog basilar artery.
Topics: Animals; Basilar Artery; Cocaine; Dogs; In Vitro Techniques; Indomethacin; Ketanserin; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Potassium; Prazosin; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Spiperone; Vasoconstriction | 1989 |
Differential actions of cocaine and amphetamine on dorsal raphe neurons in vitro.
Topics: Amphetamine; Animals; Cocaine; In Vitro Techniques; Membrane Potentials; Neurons; Prazosin; Raphe Nuclei; Rats; Serotonin; Spiperone | 1989 |
The bindings of 3H-prazosin and 3H-yohimbine to alpha adrenoceptors in the guinea-pig stomach.
Topics: Animals; Apomorphine; Binding, Competitive; Cell Membrane; Domperidone; Dopamine; Gastric Mucosa; Guinea Pigs; Male; Prazosin; Receptors, Adrenergic, alpha; Spiperone; Sympatholytics; Sympathomimetics; Tritium; Yohimbine | 1988 |
Influence of freezer storage time on cerebral biogenic amine and metabolite concentrations and receptor ligand binding characteristics.
Topics: Amygdala; Animals; Biogenic Amines; Brain; Caudate Nucleus; Dogs; Freezing; Prazosin; Quinuclidinyl Benzilate; Receptors, Adrenergic; Receptors, Catecholamine; Spiperone; Time Factors; Tissue Preservation | 1988 |
Quantitative autoradiography of major neurotransmitter receptors in the monkey striate and extrastriate cortex.
Topics: Animals; Autoradiography; Cerebral Cortex; Clonidine; Female; Flunitrazepam; Ketanserin; Macaca mulatta; Male; Muscimol; Pindolol; Prazosin; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Neurotransmitter; Serotonin; Spiperone; Visual Cortex | 1988 |
Receptor affinity, neurochemistry and behavioral characteristics of the enantiomers of thioridazine: evidence for different stereoselectivities at D1 and D2 receptors in rat brain.
Topics: Animals; Benzazepines; Brain Chemistry; Catalepsy; Dopamine Antagonists; Male; Norepinephrine; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Muscarinic; Spiperone; Stereoisomerism; Thioridazine | 1988 |
Do antipsychotic drugs and serotonin down regulate [3H]-spiroperidol binding sites in human cortex?
Topics: Adolescent; Adult; Antipsychotic Agents; Binding Sites; Butyrophenones; Cerebral Cortex; Chlorpromazine; Haloperidol; Humans; Kinetics; Middle Aged; Prazosin; Serotonin; Spiperone | 1986 |
Studies on the receptor profile of bisoprolol.
Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Bisoprolol; Cattle; Dihydroalprenolol; Domperidone; Humans; In Vitro Techniques; Ketanserin; Male; Piperidines; Prazosin; Propanolamines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Histamine; Receptors, Muscarinic; Spiperone; Tetrahydronaphthalenes; Yohimbine | 1986 |
Pharmacological profile of a new potent and specific alpha 2-adrenoceptor antagonist, L-657,743.
Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Binding, Competitive; Blood Platelets; Cattle; Cerebral Cortex; Clonidine; Humans; In Vitro Techniques; Ketanserin; Male; Prazosin; Quinolizines; Radioligand Assay; Rats; Rats, Inbred Strains; Serotonin; Spiperone; Vas Deferens | 1987 |
The pharmacological profile of Org 6906, a potential non-sedative antidepressant that combines monoamine uptake inhibition with alpha 2-adrenolytic activity.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Binding, Competitive; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Cerebral Cortex; Chickens; Male; Mice; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Spiperone | 1988 |
Subtypes of the 5-HT receptor mediating the behavioural responses to 5-methoxy-N,N-dimethyltryptamine in the rat.
Topics: Animals; Apomorphine; Behavior, Animal; Betaxolol; Haloperidol; Ketanserin; Male; Pindolol; Piperidines; Prazosin; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reserpine; Spiperone | 1985 |
Characterization of (3H)-spiperone binding to alpha 1-adrenergic receptors in a smooth muscle cell line.
Topics: Animals; Binding, Competitive; Butyrophenones; Cell Line; Cricetinae; Kinetics; Muscle, Smooth; Prazosin; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin; Spiperone | 1985 |
Fengabine, a novel antidepressant GABAergic agent. II. Effect on cerebral noradrenergic, serotonergic and GABAergic transmission in the rat.
Topics: Animals; Antidepressive Agents; Brain; Chlorophenols; Clonidine; Dihydroalprenolol; gamma-Aminobutyric Acid; Imipramine; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin; Spiperone; Synaptic Transmission | 1987 |
Neurochemical and autonomic pharmacological profiles of the 6-aza-analogue of mianserin, Org 3770 and its enantiomers.
Topics: Animals; Antidepressive Agents, Tricyclic; Autonomic Nervous System; Binding, Competitive; Cerebral Cortex; Corpus Striatum; In Vitro Techniques; Male; Mianserin; Mirtazapine; Norepinephrine; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Serotonin; Spiperone; Stereoisomerism; Synaptosomes; Yohimbine | 1988 |
A reassessment of the binding of [3H]rauwolscine to membranes from the rat cortex.
Topics: Animals; Binding, Competitive; Cerebral Cortex; In Vitro Techniques; Kinetics; Male; Membranes; Prazosin; Rats; Rats, Inbred Strains; Spiperone; Yohimbine | 1986 |
Antagonism by antidepressants of neurotransmitter receptors of normal human brain in vitro.
Topics: Antidepressive Agents; Binding, Competitive; Brain; Doxepin; Humans; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Histamine H1; Receptors, Neurotransmitter; Spiperone; Yohimbine | 1984 |
Characterisation of the mechanisms by which purported dopamine agonists reduce spontaneous locomotor activity of mice.
Topics: Animals; Antipsychotic Agents; Apomorphine; Bromocriptine; Catecholamines; Dopamine; Dose-Response Relationship, Drug; Imidazolines; Male; Mice; Motor Activity; Prazosin; Receptors, Dopamine; Spiperone; Tetrahydronaphthalenes; Yohimbine | 1981 |
Modulation of dopaminergic transmission by alpha-noradrenergic agonists and antagonists: evidence for antidopaminergic properties of some alpha antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Dopamine; Female; Haloperidol; Homovanillic Acid; Male; Prazosin; Rats; Spiperone; Synaptic Transmission; Yohimbine | 1982 |
CGS 7525A, a new, centrally active alpha 2 adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Animals; Benzodiazepines; Chemical Phenomena; Chemistry; Clonidine; Male; Mesencephalon; Mianserin; Norepinephrine; Prazosin; Quinones; Rats; Rats, Inbred Strains; Spiperone; Yohimbine | 1983 |
Motor inhibition induced by aporphine derivatives in the mouse.
Topics: Animals; Aporphines; Corpus Striatum; Drug Interactions; In Vitro Techniques; Isoquinolines; Male; Mice; Mice, Inbred Strains; Motor Activity; Prazosin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Tetrahydronaphthalenes; Yohimbine | 1983 |
Chronic administration of antidepressant drugs increases the density of cortical [3H]prazosin binding sites in the rat.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Binding Sites; Cerebral Cortex; Chlorprothixene; Citalopram; Imipramine; Male; Methotrimeprazine; Prazosin; Propylamines; Quinazolines; Rats; Rats, Inbred Strains; Spiperone | 1984 |
The citalopram/5-HTP-induced head shake syndrome is correlated to 5-HT2 receptor affinity and also influenced by other transmitters.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Binding, Competitive; Brain; Citalopram; Female; Guinea Pigs; Histamine Antagonists; Humans; Hydroxydopamines; In Vitro Techniques; Male; Neurotransmitter Agents; Oxidopamine; Prazosin; Propylamines; Propylbenzilylcholine Mustard; Rats; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Muscarinic; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Stereotyped Behavior | 1984 |
Contamination of serotonin-2 binding sites by an alpha-1 adrenergic component in assays with (3H)spiperone.
Topics: Animals; Binding Sites; Butyrophenones; Cerebral Cortex; In Vitro Techniques; Methysergide; Mice; Prazosin; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin; Spiperone; Tritium | 1984 |
Biochemical effects and drug levels in rats after long-term treatment with the specific 5-HT-uptake inhibitor, citalopram.
Topics: Amphetamines; Animals; Binding, Competitive; Brain Chemistry; Citalopram; Diet; Male; Membranes; Nerve Tissue Proteins; Prazosin; Propylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone; Synaptosomes | 1984 |
Interaction of dihydroxy-2-aminotetralin derivatives at sites labelled with [3H]clonidine, [3H]prazosin and [3H]spiperone in rat brain membranes.
Topics: Animals; Binding Sites; Brain; Butyrophenones; Cell Membrane; Cerebral Cortex; Clonidine; Drug Interactions; Male; Naphthalenes; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Spiperone; Tetrahydronaphthalenes | 1984 |
Competition by estrogens for catecholamine receptor binding in vitro.
Topics: Animals; Binding, Competitive; Brain; Cerebral Cortex; Corpus Striatum; Dioxanes; Estradiol; Estrogens; Female; Hydroxyestrones; Pituitary Gland, Anterior; Prazosin; Rats; Receptors, Adrenergic; Spiperone; Tetrahydronaphthalenes | 1982 |
Isolation and identification of tetrahydrocolumbamine as a dopamine receptor ligand from Polygala tenuifolia Willd.
Topics: Animals; Benzazepines; Berberine Alkaloids; Binding, Competitive; Cell Membrane; Corpus Striatum; Drugs, Chinese Herbal; Male; Prazosin; Rats; Rats, Wistar; Receptors, Dopamine; Spiperone | 1994 |
Mediation of noradrenaline-induced contractions of rat aorta by the alpha 1B-adrenoceptor subtype.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Computer Simulation; Hippocampus; In Vitro Techniques; Liver; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Regression Analysis; Spiperone; Stereoisomerism; Sulfonamides | 1995 |
Distribution and density of monoamine receptors in the primate visual cortex devoid of retinal input from early embryonic stages.
Topics: Animals; Anophthalmos; Benzazepines; Clonidine; Eye Enucleation; Gene Expression Regulation, Developmental; Gestational Age; Ketanserin; Macaca mulatta; Pindolol; Prazosin; Radioligand Assay; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Spiperone; Visual Cortex; Visual Pathways | 1995 |
The quipazine- and TFMPP-increased conditioned avoidance response in rats: role of 5HT1C/5-HT2 receptors.
Topics: Animals; Avoidance Learning; Conditioning, Operant; Ketanserin; Male; Mianserin; Nadolol; Pindolol; Piperazines; Prazosin; Quipazine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reference Values; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Tropanes | 1993 |
Investigation of the actions of chloroethylclonidine in rat aorta.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Aorta; Clonidine; Cystamine; Dioxanes; Dose-Response Relationship, Drug; Drug Synergism; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxathiins; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Spiperone; Xylazine; Yohimbine | 1995 |
Alpha 1B-adrenoceptor-mediated excitation of piriform cortical interneurons.
Topics: Action Potentials; Adrenergic alpha-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dioxanes; In Vitro Techniques; Interneurons; Male; Norepinephrine; Oxathiins; Phentolamine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Risperidone; Spiperone | 1996 |
Heterogeneity of alpha 1-adrenoceptor subtypes mediating noradrenaline-induced contractions of the rat superior mesenteric artery.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dioxanes; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Mesenteric Artery, Superior; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spiperone; Vasoconstriction; Vasoconstrictor Agents | 1998 |
Characterization, localization and distribution of alpha1 adrenoceptor subtype in male rabbit urethra.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Autoradiography; Dioxanes; Immunohistochemistry; Male; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha-1; Spiperone; Urethra | 1998 |
Agonist and antagonist binding to rabbit cortical 5-HT2A receptors: opposite effects of magnesium.
Topics: Amphetamines; Animals; Cerebral Cortex; Fluorobenzenes; Guanylyl Imidodiphosphate; Ketanserin; Magnesium; Methysergide; Piperidines; Prazosin; Rabbits; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone | 1998 |
Functional characterization of alpha1-adrenoceptor subtypes in longitudinal and circular muscle of human vas deferens.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Alkylating Agents; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Piperazines; Prazosin; Receptors, Adrenergic; Spiperone; Vas Deferens | 1999 |
Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone. Evidence for a third drug-binding site.
Topics: Allosteric Site; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Binding Sites; Biological Transport; Cell Membrane; CHO Cells; Cricetinae; Fluorescent Dyes; Flupenthixol; Haloperidol; Molecular Structure; Prazosin; Progesterone; Propranolol; Protein Binding; Rhodamine 123; Spiperone | 1999 |
Subtype specific regulation of human vascular alpha(1)-adrenergic receptors by vessel bed and age.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Aging; Aorta; Arteries; Celiac Artery; Dopamine Antagonists; Female; Femoral Artery; Gene Expression; Hepatic Artery; Humans; Iliac Artery; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Phenylephrine; Piperazines; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha-1; Renal Artery; RNA, Messenger; Saphenous Vein; Spiperone; Splenic Artery; Vasoconstriction | 1999 |
alpha(1)-adrenoceptor subtypes and effect of alpha(1A)-adrenoceptor agonist NS-49 on guinea pig nasal mucosa vasculature.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anilides; Animals; Blood Vessels; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Nasal Mucosa; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Spiperone; Vasoconstriction; Yohimbine | 2000 |
Cis- and trans-N-benzyl-octahydrobenzo[g]quinolines. Adrenergic and dopaminergic activity studies.
Topics: Animals; Cell Membrane; Dopamine Agents; Models, Theoretical; Prazosin; Quinolines; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Spiperone | 2001 |
Synthesis and structure-activity relationship of the isoindolinyl benzisoxazolpiperidines as potent, selective, and orally active human dopamine D4 receptor antagonists.
Topics: Administration, Oral; Animals; Apomorphine; Benzyl Compounds; Dizocilpine Maleate; Dopamine D2 Receptor Antagonists; Indoles; Infusions, Parenteral; Isoxazoles; Piperidines; Prazosin; Rats; Receptors, Dopamine D4; Serine; Spiperone; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 2002 |
The role of catecholamines in retention performance of a partially baited radial eight-arm maze for rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Benzazepines; Dopamine; Dopamine Antagonists; Haloperidol; Male; Maze Learning; Memory; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Wistar; Space Perception; Spiperone; Yohimbine | 2002 |
Vasoconstrictor responses to 5-hydroxytryptamine in the autoperfused hindquarters of spontaneously hypertensive rats.
Topics: Animals; Dose-Response Relationship, Drug; Hindlimb; Indoles; Injections, Intra-Arterial; Injections, Intravenous; Male; Perfusion; Piperazines; Prazosin; Pyridines; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT2; Regional Blood Flow; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Spiperone; Thiophenes; Vasoconstriction | 2004 |
Sympathetic neurotransmission in the rat testicular capsule: functional characterization and identification of mRNA encoding alpha1-adrenoceptor subtypes.
Topics: Acetyl-CoA C-Acyltransferase; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Calcium Channel Blockers; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Male; Muscle Contraction; Nifedipine; Norepinephrine; Prazosin; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Purinergic P2; Reserpine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spiperone; Suramin; Sympathetic Nervous System; Synaptic Transmission; Testis | 2006 |