Page last updated: 2024-08-16

spiperone and pimozide

spiperone has been researched along with pimozide in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199024 (58.54)18.7374
1990's10 (24.39)18.2507
2000's4 (9.76)29.6817
2010's3 (7.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bouthenet, ML; Giros, B; Martres, MP; Schwartz, JC; Sokoloff, P1
Andrews, PR; Craik, DJ; Martin, JL1
Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A1
Dokhan, R; el Ahmad, Y; Laurent, E; Maillet, P; Ollivier, R; Talab, A; Teste, JF; Tran, G1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L1
Glennon, RA1
Bianucci, AM; Calderone, V; Coi, A; Massarelli, I; Testai, L1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Colpaert, FC; Janssen, PA; Niemegeers, CJ1
Monti, JM1
Clark, D; Willner, P1
Mora, F; Phillips, AG; Rolls, ET1
Kuhar, MJ; Niehoff, DL; Palacios, JM1
Kuhar, MJ; Murrin, LC1
Dem, B; Holmgren, B; Urbá-Holmgren, R1
Coppings, RJ; Krulich, L; Mayfield, MA; McCann, SM1
Maj, J; Palider, W; Rawłów, A1
Laduron, P; Leysen, J1
Klimek, V; Maj, J; Rawlów, A; Sarnek, J1
Antelman, SM; Szechtman, H1
Baran, L; Sarnek, J1
Oliveira, CR; Palmeira, CM1
Kwong, LL; Peroutka, SJ; Tecott, LH; Uhr, S1
Carvalho, AP; Carvalho, CA; Leysen, JE; Lima, MC; Oliveira, CR1
Billard, R; Chang, JP; Nahorniak, CS; Omeljaniuk, RJ; Peter, RE; Shih, SH; Sokolowska, M1
McGrath, PC; Neifeld, JP2
Everitt, BJ; Fuxe, K; Hökfelt, T1
Akiyama, K; Otsuki, S; Sato, M; Yamashita, M1
Ferrer, JM; Mora, F; Sanguinetti, AM; Vives, F1
Dewey, KJ; Fibiger, HC1
Smythies, JR1
Chuang, YC; Huang, WT; Lin, MT; Liu, HS; Won, SJ1
Absil, P; Balthazart, J; Das, S1
Li, L; Schafer, JA1
Brown, C; Klein-Stevens, CL; Liang, L; White, J; Zhu, N1
Bradley, RJ; Dwyer, DS; Liu, Y1
Ohata, H; Samarghandian, S; Shibasaki, T; Yamauchi, N1
Chesneau, D; de la Riva, C; Fabre-Nys, C; Hinton, MR; Kendrick, KM; Locatelli, A; Ohkura, S1
Akaike, A; Izumi, Y; Kume, T; Matsuo, T; Sawada, H; Takada-Takatori, Y; Wakita, S1

Reviews

2 review(s) available for spiperone and pimozide

ArticleYear
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003
Interactions of catecholamines and GnRH in regulation of gonadotropin secretion in teleost fish.
    Recent progress in hormone research, 1986, Volume: 42

    Topics: Animals; Catecholamines; Dopamine; Female; Follicle Stimulating Hormone; Goldfish; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Male; Metoclopramide; Pimozide; Pituitary Hormone-Releasing Hormones; Receptors, Dopamine; Spiperone

1986

Other Studies

39 other study(ies) available for spiperone and pimozide

ArticleYear
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics.
    Nature, 1990, Sep-13, Volume: 347, Issue:6289

    Topics: Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line; Cloning, Molecular; Cricetinae; DNA; DNA Restriction Enzymes; Dopamine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Nucleic Acid Hybridization; Polymerase Chain Reaction; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Sequence Homology, Nucleic Acid; Tissue Distribution

1990
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin

1994
New benzocycloalkylpiperazines, potent and selective 5-HT1A receptor ligands.
    Journal of medicinal chemistry, 1997, Mar-14, Volume: 40, Issue:6

    Topics: Adenylyl Cyclases; Animals; Behavior, Animal; Binding, Competitive; Colforsin; Cyclic AMP; Electrophysiology; Enzyme Activation; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Piperazines; Protein Binding; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship

1997
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
    European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3

    Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes

1998
Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:11

    Topics: Amino Acid Sequence; Heart; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Neuroleptic interference with the cocaine cue: internal stimulus control of behavior and psychosis.
    Psychopharmacology, 1978, Jul-19, Volume: 58, Issue:3

    Topics: Amphetamine; Animals; Antipsychotic Agents; Behavior; Cocaine; Cues; Drug Interactions; Haloperidol; Humans; Male; Pimozide; Psychotic Disorders; Rats; Spiperone

1978
The effects of neuroleptics with central dopamine and noradrenaline receptor blocking properties in the L-DOPA and (+)-amphetamine-induced waking EEG in the rat.
    British journal of pharmacology, 1979, Volume: 67, Issue:1

    Topics: Animals; Antipsychotic Agents; Dextroamphetamine; Electroencephalography; Haloperidol; Levodopa; Male; Norepinephrine; Pimozide; Rats; Receptors, Adrenergic; Receptors, Dopamine; Sleep; Spiperone; Wakefulness

1979
A reappraisal of the interaction between tricyclic antidepressants and reserpine-like drugs.
    Psychopharmacology, 1978, Jun-15, Volume: 58, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Conditioning, Operant; Desipramine; Drug Interactions; Male; Motor Activity; Phenoxybenzamine; Phentolamine; Pimozide; Rats; Reserpine; Spiperone; Tetrabenazine; Time Factors

1978
Intracranial self-stimulation in orbitofrontal cortex and caudate nucleus of rhesus monkey: effects of apomorphine, pimozide, and spiroperidol.
    Psychopharmacology, 1979, Mar-29, Volume: 62, Issue:1

    Topics: Animals; Apomorphine; Butyrophenones; Caudate Nucleus; Cerebral Cortex; Drug Interactions; Haplorhini; Macaca mulatta; Pimozide; Self Stimulation; Spiperone

1979
In vivo receptor binding: attempts to improve specific/non-specific ratios.
    Life sciences, 1979, Sep-03, Volume: 25, Issue:10

    Topics: Animals; Binding, Competitive; Brain; Kinetics; Lysergic Acid Diethylamide; Male; Mice; Pimozide; Receptors, Dopamine; Receptors, Serotonin; Spiperone; Structure-Activity Relationship

1979
Dompamine receptors in the rat frontal cortex: an autoradiographic study.
    Brain research, 1979, Nov-16, Volume: 177, Issue:2

    Topics: Animals; Autoradiography; Brain Mapping; Frontal Lobe; Gyrus Cinguli; Limbic System; Male; Pimozide; Rats; Receptors, Dopamine; Receptors, Serotonin; Serotonin Antagonists; Spiperone

1979
Blockade of both pilocarpine and amphetamine-induced head-shaking with dopamine receptor antagonists.
    Pharmacology, biochemistry, and behavior, 1978, Volume: 8, Issue:6

    Topics: Animals; Behavior, Animal; Dextroamphetamine; Pilocarpine; Pimozide; Rats; Receptors, Dopamine; Spiperone

1978
Inhibition of prolactin secretion by a direct effect of methysergide on the pituitary lactotrophs in the rat.
    Life sciences, 1978, Oct-23, Volume: 23, Issue:16

    Topics: Animals; Depression, Chemical; Female; Male; Median Eminence; Methyltyrosines; Methysergide; Pimozide; Piribedil; Pituitary Gland; Prolactin; Rats; Spiperone; Thyrotropin; Time Factors

1978
The effect of haloperidol, spiperone and pimozide on the flexor reflex of the hind limb of the spinal rat.
    Journal of neural transmission, 1978, Volume: 43, Issue:2

    Topics: Animals; Butyrophenones; Clonidine; Denervation; Fenfluramine; Haloperidol; Hindlimb; Lysergic Acid Diethylamide; Male; Muscle Contraction; Norepinephrine; Pimozide; Rats; Receptors, Adrenergic; Receptors, Serotonin; Reflex; Serotonin; Spinal Cord; Spiperone

1978
Specific in vivo binding of neuroleptic drugs in rat brain.
    Biochemical pharmacology, 1977, May-15, Volume: 26, Issue:10

    Topics: Animals; Brain; Butyrophenones; Cerebellum; Corpus Striatum; Male; Pimozide; Rats; Spiperone; Subcellular Fractions; Time Factors

1977
On the anticataleptic action of cyproheptadine.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:2

    Topics: Animals; Atropine; Catalepsy; Clomipramine; Cyproheptadine; Desipramine; Female; Fluphenazine; Humans; Imipramine; Male; Methyltyrosines; Pilocarpine; Pimozide; Promethazine; Rats; Reserpine; Spiperone

1976
Tail pinch induces eating in sated rats which appears to depend on nigrostriatal dopamine.
    Science (New York, N.Y.), 1975, Aug-29, Volume: 189, Issue:4204

    Topics: Animals; Behavior, Animal; Consummatory Behavior; Corpus Striatum; Depression, Chemical; Dopamine; Feeding Behavior; Haloperidol; Hydroxydopamines; Male; Norepinephrine; Phentolamine; Pimozide; Rats; Receptors, Adrenergic; Receptors, Drug; Sotalol; Spiperone; Stress, Physiological; Substantia Nigra; Time Factors

1975
The effect of 5-hydroxytrytamine synthesis inhibitors on neuroleptic-induced catalepsy in rats.
    Archivum immunologiae et therapiae experimentalis, 1975, Volume: 23, Issue:4

    Topics: Amphetamines; Catalepsy; Fluphenazine; Humans; p-Chloroamphetamine; Pimozide; Reserpine; Serotonin; Spiperone; Tranquilizing Agents

1975
Partitioning and membrane disordering effects of dopamine antagonists: influence of lipid peroxidation, temperature, and drug concentration.
    Archives of biochemistry and biophysics, 1992, May-15, Volume: 295, Issue:1

    Topics: Animals; Caudate Nucleus; Diphenylhexatriene; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Hot Temperature; Intracellular Membranes; Lipid Peroxidation; Liposomes; Microsomes; Pimozide; Sheep; Solubility; Spiperone

1992
Differential modulation of dopamine D2 receptors by chronic haloperidol, nitrendipine, and pimozide.
    Biological psychiatry, 1986, Volume: 21, Issue:12

    Topics: Animals; Corpus Striatum; Haloperidol; Ion Channels; Male; Nitrendipine; Pimozide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone

1986
Partition coefficients of dopamine antagonists in brain membranes and liposomes.
    Biochemical pharmacology, 1989, Jul-01, Volume: 38, Issue:13

    Topics: Animals; Caudate Nucleus; Domperidone; Dopamine Antagonists; Haloperidol; Intracellular Membranes; Kinetics; Liposomes; Microsomes; Pimozide; Sheep; Spiperone; Thermodynamics

1989
Inhibition of human neuroblastoma by dopamine antagonists.
    Surgery, 1985, Volume: 98, Issue:2

    Topics: Animals; Cell Division; Cell Line; Domperidone; Dopamine; Dopamine Antagonists; Female; Humans; Levodopa; Mice; Mice, Nude; Neuroblastoma; Pimozide; Receptors, Dopamine; Spiperone

1985
Inhibitory role of dopamine and 5-hydroxytryptamine in the sexual behaviour of female rats.
    European journal of pharmacology, 1974, Volume: 29, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Castration; Chlorpromazine; Depression, Chemical; Dioxoles; Disulfides; Dopamine Antagonists; Estradiol; Female; Fenclonine; Fenfluramine; Imidazoles; Male; Methyltyrosines; Norepinephrine; Ovary; Pimozide; Piperazines; Progesterone; Rats; Serotonin Antagonists; Sexual Behavior, Animal; Spiperone; Stimulation, Chemical; Time Factors

1974
[Antipsychotics and kindling].
    No to shinkei = Brain and nerve, 1982, Volume: 34, Issue:9

    Topics: Amygdala; Animals; Antipsychotic Agents; Cats; Haloperidol; Kindling, Neurologic; Pimozide; Rats; Spiperone

1982
Effects of agonists and antagonists of D1 and D2 dopamine receptors on self-stimulation of the medial prefrontal cortex in the rat.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:2

    Topics: Animals; Apomorphine; Bromocriptine; Cerebral Cortex; Dose-Response Relationship, Drug; Ergolines; Functional Laterality; Male; Pimozide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Self Stimulation; Spiperone; Sulpiride; Synaptic Transmission

1983
The effects of dose and duration of chronic pimozide administration on dopamine receptor supersensitivity.
    Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 322, Issue:4

    Topics: Animals; Apomorphine; Dextroamphetamine; Dose-Response Relationship, Drug; Humans; Male; Motor Activity; Pimozide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Time Factors

1983
Inhibition of murine neuroblastoma growth by dopamine antagonists.
    The Journal of surgical research, 1984, Volume: 36, Issue:5

    Topics: Animals; Cell Line; DNA; Domperidone; Dopamine; Dopamine Antagonists; Leucine; Male; Mice; Mice, Inbred A; Neoplasm Transplantation; Neuroblastoma; Pimozide; Receptors, Dopamine; Spiperone; Thymidine

1984
An hypothesis of the molecular structure of the dopamine receptor.
    Medical hypotheses, 1981, Volume: 7, Issue:12

    Topics: Apomorphine; Chemical Phenomena; Chemistry; Dopamine; Neurotensin; Pimozide; Receptors, Cholinergic; Receptors, Dopamine; Spiperone; Thioridazine

1981
Suppression of natural killer cell activity in mouse spleen lymphocytes by several dopamine receptor antagonists.
    Experientia, 1995, Apr-15, Volume: 51, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Cytotoxicity, Immunologic; Dopamine Antagonists; Flupenthixol; Fluphenazine; Killer Cells, Natural; Mice; Mice, Inbred C3H; Pimozide; Spiperone; Spleen; Thiothixene; Trifluoperazine

1995
Effects of apomorphine on sexual behavior in male quail.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:1

    Topics: Animals; Apomorphine; Coturnix; Depression, Chemical; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Male; Pimozide; Sexual Behavior, Animal; Spiperone

1994
Dopamine inhibits vasopressin-dependent cAMP production in the rat cortical collecting duct.
    The American journal of physiology, 1998, Volume: 275, Issue:1

    Topics: Alkaloids; Animals; Arginine Vasopressin; Benzophenanthridines; Clozapine; Cyclic AMP; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enzyme Inhibitors; Epinephrine; Fenoldopam; GTP-Binding Proteins; In Vitro Techniques; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Male; Naphthalenes; Phenanthridines; Pimozide; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D3; Receptors, Dopamine D4; Spiperone; Time Factors; Yohimbine

1998
A crystallographic and molecular modeling study of butyrophenones.
    Journal of pharmaceutical sciences, 1998, Volume: 87, Issue:12

    Topics: Butyrophenones; Crystallography; Fluspirilene; Models, Molecular; Molecular Structure; Pimozide; Spiperone

1998
Dopamine receptor antagonists modulate glucose uptake in rat pheochromocytoma (PC12) cells.
    Neuroscience letters, 1999, Oct-29, Volume: 274, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Benzazepines; Biological Transport; Chlorpromazine; Clozapine; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Fluphenazine; Glucose; Haloperidol; PC12 Cells; Pimozide; Rats; Receptors, Dopamine D2; Spiperone; Sulpiride; Tritium

1999
Corticotropin-releasing factor as well as opioid and dopamine are involved in tail-pinch-induced food intake of rats.
    Neuroscience, 2003, Volume: 116, Issue:2

    Topics: Animals; Corticotropin-Releasing Hormone; Dopamine; Dopamine Antagonists; Eating; Injections, Intraventricular; Male; Naloxone; Narcotic Antagonists; Physical Stimulation; Pimozide; Pyridines; Pyrimidines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Receptors, Opioid; Spiperone; Stress, Physiological; Tail

2003
Biphasic role of dopamine on female sexual behaviour via D2 receptors in the mediobasal hypothalamus.
    Neuropharmacology, 2003, Volume: 44, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Citrulline; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Estradiol; Extracellular Space; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Goats; Hypothalamus, Middle; Luteinizing Hormone; Microdialysis; Norepinephrine; Ovariectomy; Pimozide; Prolactin; Quinpirole; Receptors, Dopamine D2; Serotonin; Sexual Behavior, Animal; Spiperone; Taurine; Time Factors

2003
Haloperidol, spiperone, pimozide and aripiprazole reduce intracellular dopamine content in PC12 cells and rat mesencephalic cultures: Implication of inhibition of vesicular transport.
    European journal of pharmacology, 2010, Aug-25, Volume: 640, Issue:1-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Aripiprazole; Ascorbic Acid; Biological Transport; Dopamine; Extracellular Space; Gene Expression Regulation, Enzymologic; Haloperidol; Homovanillic Acid; Mesencephalon; Neurons; Pargyline; PC12 Cells; Pimozide; Piperazines; Quinolones; Rats; Spiperone; Transport Vesicles; Tyrosine 3-Monooxygenase

2010