Compounds > spiperone
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spiperone and perphenazine

spiperone has been researched along with perphenazine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A1
Glennon, RA1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, Y; Liu, BF; Liu, S; Liu, X; Qiu, Y; Wang, S; Xu, X; Yu, M; Zhang, G; Zhang, T; Zhao, S1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Mjörndal, T; Persson, SA1
Suzuki, S; Yamazaki, M1
Zapata, P; Zuazo, A1

Reviews

1 review(s) available for spiperone and perphenazine

ArticleYear
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003

Other Studies

7 other study(ies) available for spiperone and perphenazine

ArticleYear
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin

1994
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Synthesis and biological investigation of coumarin piperazine (piperidine) derivatives as potential multireceptor atypical antipsychotics.
    Journal of medicinal chemistry, 2013, Jun-13, Volume: 56, Issue:11

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Biological Availability; Coumarins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; In Vitro Techniques; Isoxazoles; Lethal Dose 50; Mice; Motor Activity; Prolactin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Dopamine D3; Structure-Activity Relationship; Weight Gain

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Time-related changes in serum perphenazine, striatal 3H-spiperone binding and regional brain acid metabolites of dopamine and 5-hydroxy-tryptamine after a single dose of perphenazine.
    Fundamental & clinical pharmacology, 1990, Volume: 4, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Perphenazine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereoisomerism

1990
Toxicology of tremorgenic mycotoxins, fumitremorgin A and B.
    Developments in toxicology and environmental science, 1986, Volume: 12

    Topics: Animals; Aspartic Acid; Behavior, Animal; Brain; Chlorpromazine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Haloperidol; Harmine; Indenes; Indoles; Lethal Dose 50; Male; Mice; Perphenazine; Posture; Reserpine; Seizures; Spiperone; Triflupromazine

1986
Reversal of respiratory responses to dopamine after dopamine antagonists.
    Respiration physiology, 1982, Volume: 47, Issue:2

    Topics: Animals; Apomorphine; Cats; Chlorpromazine; Dopamine; Dopamine Antagonists; Female; Haloperidol; Male; Nitrogen; Oxygen; Perphenazine; Respiration; Spiperone

1982