Compounds > spiperone
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spiperone and nicotine

spiperone has been researched along with nicotine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19907 (35.00)18.7374
1990's9 (45.00)18.2507
2000's2 (10.00)29.6817
2010's1 (5.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM1
Bianucci, AM; Calderone, V; Coi, A; Massarelli, I; Testai, L1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Fung, YK; Lau, YS4
Creese, I; Kirch, DG; Taylor, TR; Wyatt, RJ; Xu, SX1
Kita, T; Nakashima, T; Okamoto, M1
Courtney, ND; Howlett, AC; Westfall, TC1
Coen, KM; Corrigall, WA2
Bigornia, L; Napp, D; Ryan, KA; Schneider, AS; Suozzo, M1
Lajtha, A; Sershen, H; Wiener, HL1
Artalejo, AR; García, AG; González, MC; Hervás, PP; Montiel, C1
Damaj, MI; Glennon, RA; Martin, BR1
Andersson, J; Hartvig, P; Inoue, O; Kanai, T; Långström, B; Lilja, A; Tani, Y; Watanabe, Y1
Breese, CR; Lee, MJ; Leonard, S; Strook, ML1
Abdullahi, I; Alatishe, YA; Bioku, AA; Bradford, JMW; Chaimowitz, GA; Kolawole, OF; Mela, M; Olagunju, AT; Olagunju, TO; Poluyi, C1

Reviews

1 review(s) available for spiperone and nicotine

ArticleYear
The role of receptor binding in drug discovery.
    Journal of natural products, 1993, Volume: 56, Issue:4

    Topics: Animals; Drug Design; Humans; Receptors, Drug

1993

Other Studies

19 other study(ies) available for spiperone and nicotine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:11

    Topics: Amino Acid Sequence; Heart; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Chronic effects of nicotine on mesolimbic dopaminergic system in rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:1

    Topics: alpha-Methyltyrosine; Animals; Dextroamphetamine; Dopamine; Dopamine Antagonists; gamma-Aminobutyric Acid; Injections; Limbic System; Male; Methyltyrosines; Motor Activity; Nicotine; Nucleus Accumbens; Potassium; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Nicotinic; Spiperone; Tyrosine 3-Monooxygenase

1992
Effect of chronic nicotine treatment and withdrawal on rat striatal D1 and D2 dopamine receptors.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:2

    Topics: Animals; Benzazepines; Corpus Striatum; Male; Nicotine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Substance Withdrawal Syndrome

1992
Nicotine-induced sensitization to ambulatory stimulant effect produced by daily administration into the ventral tegmental area and the nucleus accumbens in rats.
    Life sciences, 1992, Volume: 50, Issue:8

    Topics: Animals; Benzazepines; Male; Mecamylamine; Motor Activity; Nicotine; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Spiperone; Tegmentum Mesencephali

1992
Dopaminergic regulation of dopamine release from PC12 cells via a pertussis toxin-sensitive G protein.
    Neuroscience letters, 1991, Jan-28, Volume: 122, Issue:2

    Topics: Adrenal Gland Neoplasms; Animals; Apomorphine; Cell Line; Dopamine; Dopamine Antagonists; Ergolines; GTP-Binding Proteins; Haloperidol; Nicotine; Pertussis Toxin; Pheochromocytoma; Potassium; Quinpirole; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Virulence Factors, Bordetella

1991
Selective dopamine antagonists reduce nicotine self-administration.
    Psychopharmacology, 1991, Volume: 104, Issue:2

    Topics: Animals; Benzazepines; Conditioning, Operant; Dopamine Antagonists; Food; Haloperidol; Male; Motor Activity; Nicotine; Rats; Reinforcement Schedule; Self Administration; Spiperone

1991
Dopamine receptors on adrenal chromaffin cells modulate calcium uptake and catecholamine release.
    Journal of neurochemistry, 1988, Volume: 51, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Animals; Apomorphine; Butaclamol; Calcium; Calcium Radioisotopes; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Electric Conductivity; Haloperidol; Ion Channels; Nicotine; Potassium; Receptors, Dopamine; Spiperone; Sulpiride

1988
Dopamine D1 receptor and dopamine D2 receptor binding activity changes during chronic administration of nicotine in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice.
    Neuropharmacology, 1989, Volume: 28, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzazepines; Corpus Striatum; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Nicotine; Pyridines; Receptors, Dopamine; Spiperone

1989
Effect of nicotine pretreatment on striatal dopaminergic system in rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:1

    Topics: Amphetamine; Animals; Corpus Striatum; Cotinine; Dopamine; Infusion Pumps; Locomotion; Male; Nicotine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Tyrosine

1989
Effects of prenatal nicotine exposure on rat striatal dopaminergic and nicotinic systems.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Weight; Corpus Striatum; Cotinine; Female; Gestational Age; Growth; Male; Motor Activity; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Nicotinic; Reproduction; Spiperone

1989
Receptor mechanisms of nicotine-induced locomotor hyperactivity in chronic nicotine-treated rats.
    European journal of pharmacology, 1988, Aug-02, Volume: 152, Issue:3

    Topics: Animals; Body Weight; Corpus Striatum; Dopamine; Drinking; Eating; Male; Motor Activity; Nicotine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Spiperone

1988
Characterization of a dopaminergic receptor that modulates adrenomedullary catecholamine release.
    Journal of neurochemistry, 1986, Volume: 47, Issue:2

    Topics: Adrenal Medulla; Animals; Apomorphine; Binding, Competitive; Catecholamines; Cattle; Cell Membrane; Haloperidol; Kinetics; Nicotine; Rats; Receptors, Dopamine; Spiperone

1986
Dopamine mechanisms play at best a small role in the nicotine discriminative stimulus.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:3

    Topics: Animals; Benzazepines; Cocaine; Cues; Discrimination Learning; Discrimination, Psychological; Dopamine; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Generalization, Stimulus; Male; Neurotransmitter Uptake Inhibitors; Nicotine; Piperazines; Rats; Receptors, Dopamine D1; Reinforcement Schedule; Spiperone

1994
Involvement of the serotonergic system in the hypoactive and antinociceptive effects of nicotine in mice.
    Brain research bulletin, 1994, Volume: 33, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Ketanserin; Locomotion; Male; Mice; Mice, Inbred ICR; Nicotine; Nociceptors; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone

1994
Positron emission tomography studies on some neurotransmitter receptor systems with 6R-tetrahydrobiopterin pretreatment.
    Advances in experimental medicine and biology, 1993, Volume: 338

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzazepines; Benztropine; Biopterins; Brain; Carbon Radioisotopes; Dopamine Antagonists; Glucose; Macaca mulatta; Nicotine; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Neurotransmitter; Regional Blood Flow; Spiperone; Tomography, Emission-Computed

1993
The effect of nicotine and haloperidol co-treatment on nicotinic receptor levels in the rat brain.
    Brain research. Molecular brain research, 2001, Jan-31, Volume: 86, Issue:1-2

    Topics: Aconitine; Animals; Brain Chemistry; Bridged Bicyclo Compounds, Heterocyclic; Dopamine Antagonists; Haloperidol; Insecticides; Male; Nicotine; Nicotinic Agonists; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Muscarinic; Receptors, Nicotinic; Schizophrenia; Smoking; Spiperone; Tritium

2001
Substance Use Disorders and Antisocial Personality Disorder among a Sample of Incarcerated Individuals with Inadequate Health Care: Implications for Correctional Mental-Behavioural Health and Addiction Services.
    Journal of health care for the poor and underserved, 2022, Volume: 33, Issue:3

    Topics: Adult; Antisocial Personality Disorder; Delivery of Health Care; Female; Humans; Male; Nicotine; Prisoners; Spiperone; Substance-Related Disorders

2022