Page last updated: 2024-08-16

spiperone and metoclopramide

spiperone has been researched along with metoclopramide in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199014 (60.87)18.7374
1990's5 (21.74)18.2507
2000's3 (13.04)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fang, X; Hu, Z; Levant, B; Min, J; Varady, J; Wang, S; Wu, X1
Artursson, P; Mateus, A; Matsson, P1
Iuvone, PM1
Billard, R; Chang, JP; Nahorniak, CS; Omeljaniuk, RJ; Peter, RE; Shih, SH; Sokolowska, M1
Besharse, JC; Stone, S; Witkovsky, P1
Ozaki, L; Stern, N; Tuck, ML1
Fahn, S; Hassan, MN; Higgins, D; Kuhn, C; Reches, A1
Csernansky, CA; Csernansky, JG; Hollister, LE1
Herberg, LJ; Wishart, TB1
Dvorkin, B; Klein, PN; Makman, MH; Rosenfeld, MR1
Gershon, S; Lautin, A; Rotrosen, J; Stanley, M; Wazer, D1
Florvall, L; Hall, H; Ogren, SO1
Idoipe, A; Idoipe, C; Sanz, F1
Benson, DI; Kuhn, CM; Meyerson, LR; Stanley, M; Virgilio, J; Wazer, D1
Creese, I; Hamblin, MW; Leff, SE1
Gershon, S; Lautin, A; Rotorsen, J; Stanley, M; Wazer, D1
Brooks, K; Farooqui, T; Harrold, MW; Miller, DD; Uretsky, NJ; Wallace, LJ1
Balduini, W; Cantalamessa, F; Cardellini, M; Claudi, F; Di Stefano, A; Giorgioni, G; RenĂ², F1
Appadu, BL; Lambert, DG; Strange, PG1
Lynch, AM; See, RE; Sorg, BA1
Hirokawa, Y; Kato, S; Morie, T; Yamazaki, H; Yoshida, N1
Li, Y; Matsuda, H; Yoshikawa, M1
Agovic, MS; Banerjee, SP; Lidsky, TI; Yablonsky-Alter, E1

Reviews

1 review(s) available for spiperone and metoclopramide

ArticleYear
Interactions of catecholamines and GnRH in regulation of gonadotropin secretion in teleost fish.
    Recent progress in hormone research, 1986, Volume: 42

    Topics: Animals; Catecholamines; Dopamine; Female; Follicle Stimulating Hormone; Goldfish; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Male; Metoclopramide; Pimozide; Pituitary Hormone-Releasing Hormones; Receptors, Dopamine; Spiperone

1986

Other Studies

22 other study(ies) available for spiperone and metoclopramide

ArticleYear
Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Algorithms; Binding Sites; Computational Biology; Crystallography, X-Ray; Databases, Protein; Humans; Kinetics; Ligands; Lipid Bilayers; Models, Molecular; Molecular Conformation; Mutation; Receptors, Dopamine D2; Receptors, Dopamine D3; Reproducibility of Results; Solvents; Structure-Activity Relationship; Tetrahydronaphthalenes; Water

2003
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Evidence for a D2 dopamine receptor in frog retina that decreases cyclic AMP accumulation and serotonin N-acetyltransferase activity.
    Life sciences, 1986, Jan-27, Volume: 38, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Bucladesine; Calcium; Circadian Rhythm; Cyclic AMP; Dopamine; Ergolines; Light; Metoclopramide; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D2; Retina; Spiperone; Xenopus laevis

1986
Dopamine modifies the balance of rod and cone inputs to horizontal cells of the Xenopus retina.
    Brain research, 1988, May-24, Volume: 449, Issue:1-2

    Topics: Animals; Benzazepines; Dopamine; Dopamine Antagonists; Evoked Potentials; Membrane Potentials; Metoclopramide; Photic Stimulation; Photoreceptor Cells; Retina; Retinal Ganglion Cells; Spiperone; Xenopus

1988
Evidence for dopaminergic binding sites in the human adrenal cortex.
    Metabolism: clinical and experimental, 1986, Volume: 35, Issue:12

    Topics: Adrenal Cortex; Adult; Aged; Apomorphine; Binding, Competitive; Bromocriptine; Domperidone; Dopamine; Epinephrine; Female; Humans; Ketanserin; Male; Metoclopramide; Middle Aged; Receptors, Dopamine; Spiperone; Sulpiride; Time Factors

1986
Pharmacologic evaluation of dopaminergic receptor blockade by metoclopramide.
    Clinical neuropharmacology, 1986, Volume: 9, Issue:1

    Topics: Animals; Behavior, Animal; Catalepsy; Dopamine; Haloperidol; Male; Metoclopramide; Motor Activity; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior

1986
3[H]-Sulpiride labels mesolimbic non-dopaminergic sites that bind antidepressant drugs.
    Experientia, 1985, Nov-15, Volume: 41, Issue:11

    Topics: Amygdala; Animals; Antidepressive Agents; Binding Sites; Binding, Competitive; Corpus Striatum; Kinetics; Male; Metoclopramide; Nucleus Accumbens; Rats; Septal Nuclei; Spiperone; Sulpiride; Tiapamil Hydrochloride

1985
Selective permeation of the blood-brain barrier as a cause of the anomalous properties of 'atypical'neuroleptics.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:6

    Topics: Animals; Antipsychotic Agents; Blood-Brain Barrier; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Metoclopramide; Rats; Self Stimulation; Spiperone

1980
Differential affinities of molindone, metoclopramide and domperidone for classes of [3H]spiroperidol binding sites in rat striatum: evidence for pharmacologically distinct classes of receptors.
    Brain research, 1982, Mar-04, Volume: 235, Issue:1

    Topics: Animals; Antipsychotic Agents; Binding, Competitive; Corpus Striatum; Domperidone; Dopamine; Male; Metoclopramide; Molindone; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone

1982
Discrimination of functionally heterogeneous receptor subpopulations: antipsychotic and antidopaminergic properties of metoclopramide [proceedings].
    Psychopharmacology bulletin, 1981, Volume: 17, Issue:1

    Topics: Animals; Apomorphine; Binding Sites; Humans; Metoclopramide; Rats; Receptors, Dopamine; Receptors, Neurotransmitter; Schizophrenia; Spiperone

1981
Effect of lipophilicity of substituted benzamides on the dopaminergic effects in vivo and in vitro.
    Acta pharmacologica et toxicologica, 1984, Volume: 55, Issue:3

    Topics: Animals; Benzamides; Binding, Competitive; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Lipids; Male; Metoclopramide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Sulpiride

1984
Dopaminergic receptors in guinea-pig bladder.
    Veterinary research communications, 1983, Volume: 7, Issue:1-4

    Topics: Animals; Domperidone; Dopamine; Guinea Pigs; Haloperidol; In Vitro Techniques; Metoclopramide; Radioligand Assay; Receptors, Dopamine; Spiperone; Urinary Bladder

1983
Lack of potency of metoclopramide's metabolites in various dopaminergic models.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:2

    Topics: Animals; Apomorphine; Dopamine; Fluphenazine; Haloperidol; Homovanillic Acid; Humans; Male; Metoclopramide; Prolactin; Rats; Rats, Inbred Strains; Spiperone; Stereotyped Behavior; Tetrahydronaphthalenes

1983
Interactions of agonists with D-2 dopamine receptors: evidence for a single receptor population existing in multiple agonist affinity-states in rat striatal membranes.
    Biochemical pharmacology, 1984, Mar-15, Volume: 33, Issue:6

    Topics: Animals; Binding, Competitive; Butyrophenones; Corpus Striatum; Domperidone; Dopamine Antagonists; Guanine Nucleotides; Ketanserin; Metoclopramide; Piperidines; Radioligand Assay; Rats; Receptors, Dopamine; Sodium; Spiperone; Temperature

1984
Chronic treatment with metoclopramide induces behavioral supersensitivity to apomorphine and enhances specific binding of 3H-spiroperidol to rat striata.
    Life sciences, 1980, Jul-28, Volume: 27, Issue:4

    Topics: Animals; Apomorphine; Behavior, Animal; Binding, Competitive; Body Weight; Butyrophenones; Corpus Striatum; Male; Metoclopramide; Rats; Spiperone; Time Factors

1980
Interaction of permanently charged metoclopramide analogs with D-2 dopamine receptors.
    General pharmacology, 1994, Volume: 25, Issue:8

    Topics: Animals; Corpus Striatum; Hydrogen-Ion Concentration; In Vitro Techniques; Ions; Metoclopramide; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Spiperone

1994
Activity of N-(2-phenylethyl)-N-n-propyl-2-(3-hydroxyphenyl) ethylamine derivatives as dopamine receptor ligands.
    Drug design and discovery, 1994, Volume: 11, Issue:2

    Topics: Animals; Benzazepines; Dopamine Agents; Ethylamines; In Vitro Techniques; Ligands; Metoclopramide; Motor Activity; Neostriatum; Phenethylamines; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Stereotyped Behavior

1994
Does propofol interact with D2 dopamine receptors?
    Anesthesia and analgesia, 1994, Volume: 79, Issue:6

    Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Kinetics; Metoclopramide; Propofol; Receptors, Dopamine D2; Spiperone; Tritium

1994
Subchronic administration of clozapine, but not haloperidol or metoclopramide, decreases dopamine D2 receptor messenger RNA levels in the nucleus accumbens and caudate-putamen in rats.
    Neuroscience, 1996, Volume: 72, Issue:1

    Topics: Actins; Animals; Antipsychotic Agents; Blotting, Northern; Brain Chemistry; Caudate Nucleus; Clozapine; Dopamine Antagonists; Haloperidol; Male; Metoclopramide; Nucleus Accumbens; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; RNA, Messenger; Spiperone

1996
A novel series of N-(hexahydro-1,4-diazepin-6-yl) and N-(hexahydroazepin- 3-yl)benzamides with high affinity for 5-HT3 and dopamine D2 receptors.
    Bioorganic & medicinal chemistry letters, 1998, Mar-17, Volume: 8, Issue:6

    Topics: Animals; Benzamides; Binding Sites; Cerebral Cortex; Corpus Striatum; Domperidone; Dopamine Antagonists; Imidazoles; Indoles; Ligands; Metoclopramide; Models, Chemical; Ondansetron; Rats; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Spiperone; Stereoisomerism

1998
Possible involvement of dopamine and dopamine2 receptors in the inhibitions of gastric emptying by escin Ib in mice.
    Life sciences, 2000, Nov-03, Volume: 67, Issue:24

    Topics: alpha-Methyltyrosine; Animals; Benzazepines; Domperidone; Dopamine; Dose-Response Relationship, Drug; Escin; Gastric Emptying; Haloperidol; Male; Metoclopramide; Mice; Oxidopamine; Receptors, Dopamine; Reserpine; Spiperone

2000
Mechanisms for metoclopramide-mediated sensitization and haloperidol-induced catalepsy in rats.
    European journal of pharmacology, 2008, Jun-10, Volume: 587, Issue:1-3

    Topics: Animals; Behavior, Animal; Binding, Competitive; Catalepsy; Cerebral Cortex; Dizocilpine Maleate; Dopamine Antagonists; Haloperidol; Male; Metoclopramide; Neostriatum; Rats; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Spiperone

2008