spiperone has been researched along with methiothepin in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (25.00) | 18.7374 |
| 1990's | 16 (57.14) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 1 (3.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamblin, MW; Metcalf, MA | 1 |
| Adham, N; Bard, JA; Branchek, TA; Vaysse, P; Weinshank, RL; Zgombick, J | 1 |
| Amlaiky, N; Hen, R; Plassat, JL | 1 |
| Chang, DJ; Eglen, RM; Jasper, JR; Kosaka, A; To, ZP | 1 |
| Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB | 1 |
| Chaput, C; Millan, MJ; Newman-Tancredi, A; Verrièle, L | 1 |
| Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L | 1 |
| Bach, T; Krobert, KA; Kvingedal, AM; Levy, FO; Syversveen, T | 1 |
| Glennon, RA | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Lepailleur, A; Rochais, C; Thirumaran, SL | 1 |
| Glowinski, J; Hamon, M; Herbet, A; Nelson, DL; Pichat, L | 1 |
| Newman-Tancredi, A; Strange, PG; Sundaram, H | 1 |
| Motevalian, M; Parsons, AA; Whalley, ET | 1 |
| Feniuk, W; Humphrey, PP; Perren, MJ | 1 |
| Blier, P; Chaput, Y; de Montigny, C; Steinberg, S | 1 |
| Jenner, P; Marsden, CD; Stewart, BR | 1 |
| Anderson, EG; Marszalec, W; Scroggs, RS | 1 |
| Hotta, I; Segawa, T; Yamawaki, S | 1 |
| Oelssner, W; Raubach, KH | 1 |
| Martin, LL; Sanders-Bush, E | 1 |
| Wallis, DI; Wang, XC; Wu, J | 1 |
| Blier, P; de Montigny, C; Dennis, T | 1 |
| Blier, P; De Montigny, C; Lista, A | 1 |
| Palmier, C; Pauwels, PJ | 1 |
| Nishimura, Y | 1 |
| Alper, RH; Nelson, DL | 1 |
| Abrams, TW; Cohen, JE; Dumitriu, B; Negroiu, AM; Wan, Q | 1 |
2 review(s) available for spiperone and methiothepin
| Article | Year |
|---|---|
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
Structure-activity relationships of serotonin 5-HT
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship | 2019 |
26 other study(ies) available for spiperone and methiothepin
| Article | Year |
|---|---|
Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cyclic AMP; GTP-Binding Proteins; Humans; Molecular Sequence Data; Pertussis Toxin; Receptors, Serotonin; Virulence Factors, Bordetella | 1991 |
Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.
Topics: Adenylyl Cyclases; Base Sequence; Cloning, Molecular; DNA Primers; Humans; Molecular Sequence Data; Receptors, Serotonin; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction | 1993 |
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b).
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Humans; Molecular Sequence Data; Placenta; Radioligand Assay; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid | 1997 |
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor.
Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine | 1998 |
Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Affinity Labels; Animals; Binding, Competitive; CHO Cells; Cricetinae; Guanine Nucleotides; Hippocampus; Humans; Male; Membranes; Piperazines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 1998 |
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes | 1998 |
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution.
Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Brain; Cell Line; Cloning, Organism; Genetic Variation; Humans; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution | 2001 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
In vitro and in vivo disposition of 3H-methiothepin in brain tissues. Relationship to the effects of acute treatment with methiothepin on central serotoninergic receptors.
Topics: Adenylyl Cyclases; Animals; Brain; Dibenzothiepins; Haloperidol; Male; Membranes; Methiothepin; Rats; Receptors, Serotonin; Serotonin; Spiperone; Synaptosomes; Time Factors | 1979 |
Pharmacological characterisation of the 5-HT1A serotonin receptor using the agonist [3H]8-OH-DPAT, and the antagonist [3H]spiperone.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; CHO Cells; Cricetinae; Humans; Kinetics; Lisuride; Methiothepin; Pindolol; Receptors, Serotonin; Recombinant Proteins; Serotonin; Serotonin Antagonists; Spiperone; Transfection; Tritium | 1992 |
Contractile effects of 8-hydroxy-2-(di-n-propylamino)tetralin and flesinoxan in human isolated basilar artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Antihypertensive Agents; Basilar Artery; Humans; In Vitro Techniques; Indoles; Methiothepin; Muscle Contraction; Muscle, Smooth, Vascular; Phentolamine; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone; Sulfonamides; Sumatriptan; Tetrahydronaphthalenes; Vasoconstrictor Agents | 1991 |
Vascular 5-HT1-like receptors that mediate contraction of the dog isolated saphenous vein and carotid arterial vasoconstriction in anaesthetized dogs are not of the 5-HT1A or 5-HT1D subtype.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Atropine; Carotid Arteries; Dogs; Ganglionic Blockers; In Vitro Techniques; Indoles; Ketanserin; Methiothepin; Muscle, Smooth, Vascular; Pyrilamine; Receptors, Serotonin; Saphenous Vein; Spiperone; Sulfonamides; Sumatriptan; Tetrahydronaphthalenes; Vasoconstriction; Vasoconstrictor Agents | 1991 |
Electrophysiological assessment of putative antagonists of 5-hydroxytryptamine receptors: a single-cell study in the rat dorsal raphe nucleus.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electrophysiology; Lysergic Acid Diethylamide; Male; Methiothepin; Neurons; Propranolol; Quinazolines; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin Antagonists; Spiperone; Tetrahydronaphthalenes | 1989 |
Induction of purposeless chewing behaviour in rats by 5-HT agonist drugs.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Male; Methiothepin; Methoxydimethyltryptamines; Mianserin; Parasympatholytics; Piperazines; Propranolol; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes | 1989 |
Serotonin-induced reduction of the calcium-dependent plateau in frog dorsal root ganglion cells is blocked by serotonergic agents acting at 5-hydroxytryptamine1A sites.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Calcium; Dioxanes; Ganglia, Spinal; Methiothepin; Rana catesbeiana; Receptors, Serotonin; Serotonin; Spiperone; Spiro Compounds; Tetrahydronaphthalenes | 1988 |
Long-term lithium treatment causes serotonin receptor down-regulation via serotonergic presynapses in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Frontal Lobe; Head; Hippocampus; In Vitro Techniques; Ketanserin; Lithium; Male; Methiothepin; Muscle Contraction; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Time Factors | 1986 |
[Effect of in vitro serotonin on dopaminergic binding sites in rat striatal membranes].
Topics: Animals; Apomorphine; Binding, Competitive; Corpus Striatum; In Vitro Techniques; Membranes; Methiothepin; Rats; Receptors, Dopamine; Serotonin; Spiperone | 1983 |
The serotonin autoreceptor: antagonism by quipazine.
Topics: Animals; Calcium; Fluoxetine; Hypothalamus; In Vitro Techniques; Male; Methiothepin; Phentolamine; Potassium; Quinolines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone | 1982 |
Is 5-hydroxytryptamine mediating descending inhibition in the neonatal rat spinal cord through different receptor subtypes?
Topics: Animals; Animals, Newborn; Citalopram; Dioxanes; Dopamine Antagonists; Electric Stimulation; Ketanserin; Lumbar Vertebrae; Methiothepin; Methysergide; Rats; Receptors, Serotonin; Reflex, Monosynaptic; Serotonin; Spinal Cord; Spinal Nerve Roots; Spiperone; Spiro Compounds; Sulpiride; Sumatriptan | 1993 |
Delayed effects of spiperone on serotonin1A receptors in the dorsal hippocampus of rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Culture Techniques; GTP-Binding Proteins; Hippocampus; Male; Methiothepin; Raphe Nuclei; Rats; Receptors, Serotonin; Spiperone; Synapses | 1993 |
Differential properties of pre- and postsynaptic 5-hydroxytryptamine1A receptors in the dorsal raphe and hippocampus: I. Effect of spiperone.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Drug Antagonism; gamma-Aminobutyric Acid; Hippocampus; Male; Methiothepin; Neurons; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone; Synapses | 1993 |
Functional effects of the 5-HT1D receptor antagonist GR 127,935 at human 5-HT1D alpha, 5-HT1D beta, 5-HT1A and opossum 5-HT1B receptors.
Topics: Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; HeLa Cells; Humans; Methiothepin; Opossums; Oxadiazoles; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Transfection | 1995 |
Characterization of 5-hydroxytryptamine receptors mediating contractions in basilar arteries from stroke-prone spontaneously hypertensive rats.
Topics: Animals; Basilar Artery; Dose-Response Relationship, Drug; In Vitro Techniques; Ketanserin; Male; Methiothepin; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Serotonin; Serotonin; Serotonin Agents; Spiperone | 1996 |
Characterization of 5-HT1A receptor-mediated [35S]GTPgammaS binding in rat hippocampal membranes.
Topics: Animals; Cell Membrane; Frontal Lobe; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hippocampus; Kinetics; Male; Methiothepin; Piperazines; Protein Binding; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sulfur Radioisotopes; Temperature | 1998 |
Serotonin receptor antagonists discriminate between PKA- and PKC-mediated plasticity in aplysia sensory neurons.
Topics: Action Potentials; Adenylyl Cyclases; Animals; Aplysia; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Long-Term Synaptic Depression; Methiothepin; Neuronal Plasticity; Neurons, Afferent; Nifedipine; Protein Kinase C; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Signal Transduction; Spiperone; Synapses; Type C Phospholipases | 2006 |