spiperone has been researched along with metergoline in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (45.71) | 18.7374 |
| 1990's | 10 (28.57) | 18.2507 |
| 2000's | 5 (14.29) | 29.6817 |
| 2010's | 4 (11.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamblin, MW; Metcalf, MA | 1 |
| Glennon, RA | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Adham, N; Bard, JA; Branchek, TA; Vaysse, P; Weinshank, RL; Zgombick, J | 1 |
| Amlaiky, N; Hen, R; Plassat, JL | 1 |
| Arrang, JM; Diaz, J; Leurs, R; Ruat, M; Schwartz, JC; Tardivel-Lacombe, J; Traiffort, E | 1 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Chang, DJ; Eglen, RM; Jasper, JR; Kosaka, A; To, ZP | 1 |
| Benhamú, B; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Porras, E; Ramos, JA | 1 |
| Bach, T; Krobert, KA; Kvingedal, AM; Levy, FO; Syversveen, T | 1 |
| Benhamú, B; Campillo, M; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Olivella, M; Pardo, L; Porras, E; Ramos, JA; Soto, LJ | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Lepailleur, A; Rochais, C; Thirumaran, SL | 1 |
| Boggan, WO; Buckholtz, NS; Meyer, JS | 1 |
| Fuller, RW; Snoddy, HD | 2 |
| Kordecka, A; Maj, J; Mogilnicka, E | 1 |
| Aulakh, CS; Hill, JL; Murphy, DL | 1 |
| Ashby, CR; Edwards, E; Wang, RY | 1 |
| Davies, M; Fletcher, PJ | 1 |
| Cowen, PJ; Gartside, SE | 1 |
| Brazell, C; Dourish, CT; King, BH; Middlemiss, DN | 1 |
| Barone, D; Bendotti, C; Caccia, S; Garattini, S; Mennini, T; Samanin, R | 1 |
| Chojnacka-Wójcik, E; Jaros, T; Kłodzińska, A; Maj, J | 1 |
| Appel, JB; Cunningham, KA | 1 |
| Brunello, N; Monopoli, A; Ongini, E; Racagni, G; Rovescalli, AC | 1 |
| Hruska, RE; Silbergeld, EK | 1 |
| Marsden, CA; Middlemiss, DN; Stolz, JF | 1 |
| Bennett, JL; Pax, RA; Siefker, C | 1 |
| Blackshear, MA; Friedman, RL; Sanders-Bush, E | 1 |
| Holmgren, B; Urbá-Holmgren, R | 1 |
| Katz, JL; Kopajtic, TA; Terry, P | 1 |
2 review(s) available for spiperone and metergoline
| Article | Year |
|---|---|
Central serotonin receptors as targets for drug research.
Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin | 1987 |
Structure-activity relationships of serotonin 5-HT
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship | 2019 |
33 other study(ies) available for spiperone and metergoline
| Article | Year |
|---|---|
Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cyclic AMP; GTP-Binding Proteins; Humans; Molecular Sequence Data; Pertussis Toxin; Receptors, Serotonin; Virulence Factors, Bordetella | 1991 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.
Topics: Adenylyl Cyclases; Base Sequence; Cloning, Molecular; DNA Primers; Humans; Molecular Sequence Data; Receptors, Serotonin; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction | 1993 |
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Brain; CHO Cells; Cricetinae; Cyclic AMP; DNA; Genomic Library; Kinetics; Lysergic Acid Diethylamide; Mianserin; Molecular Sequence Data; Multigene Family; Oligodeoxyribonucleotides; Organ Specificity; Rats; Receptors, Serotonin; Restriction Mapping; Serotonin; Serotonin Receptor Agonists; Transfection | 1993 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b).
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Humans; Molecular Sequence Data; Placenta; Radioligand Assay; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid | 1997 |
First pharmacophoric hypothesis for 5-HT7 antagonism.
Topics: Animals; Cell Membrane; Drug Design; Drug Evaluation, Preclinical; Hypothalamus; Models, Molecular; Rats; Receptors, Serotonin; Reproducibility of Results; Serotonin Antagonists; Structure-Activity Relationship | 2000 |
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution.
Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Brain; Cell Line; Cloning, Organism; Genetic Variation; Humans; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution | 2001 |
Optimization of the pharmacophore model for 5-HT7R antagonism. Design and synthesis of new naphtholactam and naphthosultam derivatives.
Topics: Animals; Binding, Competitive; Computer Simulation; Drug Design; Hypothalamus; In Vitro Techniques; Lactams; Ligands; Male; Models, Molecular; Molecular Conformation; Naphthalenes; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides; Thiazoles | 2003 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Serotonergic stimulation of pituitary-adrenal activity in the mouse.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Benserazide; Carbidopa; Carbolines; Corticosterone; Cyproheptadine; Female; Fenclonine; Indoles; Metergoline; Mice; Pargyline; Phenyl Ethers; Pituitary-Adrenal System; Propylamines; Quinolines; Quipazine; Spiperone; Tryptophan | 1978 |
The effects of metergoline and other serotonin receptor antagonists on serum corticosterone in rats.
Topics: Animals; Corticosterone; Cyproheptadine; Ergolines; Male; Metergoline; Methysergide; Rats; Serotonin Antagonists; Spiperone; Structure-Activity Relationship | 1979 |
Chronic treatment with antidepressant drugs: potentiation of apomorphine-induced aggressive behaviour in rats.
Topics: Aggression; Animals; Antidepressive Agents; Apomorphine; Behavior; Drug Interactions; Humans; Male; Metergoline; Phenoxybenzamine; Phentolamine; Rats; Spiperone; Stereotyped Behavior; Time Factors | 1979 |
Effects of various serotonin receptor subtype-selective antagonists alone and on m-chlorophenylpiperazine-induced neuroendocrine changes in rats.
Topics: Animals; Corticosterone; Ergolines; Male; Metergoline; Mianserin; Neurosecretory Systems; Piperazines; Prolactin; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiperone | 1992 |
Action of serotonin in the medial prefrontal cortex: mediation by serotonin3-like receptors.
Topics: Analysis of Variance; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Frontal Lobe; Indoles; Injections, Intravenous; Iontophoresis; Male; Metergoline; Pindolol; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Spiperone; Tropisetron | 1992 |
A pharmacological analysis of the eating response induced by 8-OH-DPAT injected into the dorsal raphé nucleus reveals the involvement of a dopaminergic mechanism.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dopamine; Drug Interactions; Eating; Haloperidol; Injections; Male; Metergoline; Naphthalenes; Propranolol; Raphe Nuclei; Rats; Rats, Inbred Strains; Spiperone; Tetrahydronaphthalenes | 1990 |
Mediation of ACTH and prolactin responses to 5-HTP by 5-HT2 receptors.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Animals; Dose-Response Relationship, Drug; Ketanserin; Male; Metergoline; Piperidines; Prolactin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiperone | 1990 |
MK-212 increases rat plasma ACTH concentration by activation of the 5-HT1C receptor subtype.
Topics: Adrenocorticotropic Hormone; Animals; Antiparkinson Agents; Ergolines; Ketanserin; Male; Metergoline; Pindolol; Piperazines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone | 1989 |
Evidence that central 5-HT2 receptors do not play an important role in the anorectic activity of D-fenfluramine in the rat.
Topics: Animals; Appetite Depressants; Brain Chemistry; Eating; Fenfluramine; Histamine H2 Antagonists; Male; Metergoline; Norfenfluramine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Spiperone | 1989 |
Exploratory hypoactivity induced by m-trifluoromethylphenylpiperazine (TFMPP) and m-chlorophenylpiperazine (m-CPP).
Topics: Animals; Ergolines; Exploratory Behavior; Male; Metergoline; Mianserin; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone | 1989 |
Possible 5-hydroxytryptamine1 (5-HT1) receptor involvement in the stimulus properties of 1-(m-trifluoromethylphenyl)piperazine (TFMPP).
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Discrimination Learning; Dose-Response Relationship, Drug; Indoles; Lysergic Acid Diethylamide; Male; Metergoline; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes | 1986 |
Absence of [3H]SCH 23390 specific binding sites in anterior pituitary: dissociation from effects on prolactin secretion.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Binding Sites; Corpus Striatum; Cyproheptadine; Ergolines; Kinetics; Male; Metergoline; Pituitary Gland, Anterior; Prolactin; Quinpirole; Rats; Rats, Inbred Strains; Spiperone | 1987 |
Inhibition of neurotransmitter receptor binding by ergot derivatives.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Bromocriptine; Dioxanes; Ergolines; Ergot Alkaloids; gamma-Aminobutyric Acid; Lysergic Acid Diethylamide; Male; Metergoline; Organ Specificity; Quinuclidinyl Benzilate; Rats; Receptors, Neurotransmitter; Serotonin; Spiperone; Structure-Activity Relationship; Synapses | 1981 |
Elevation of serum corticosterone concentrations in rats by pergolide and other dopamine agonists.
Topics: Animals; Antiparkinson Agents; Corticosterone; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Ergolines; Haloperidol; Male; Metergoline; Mianserin; Pergolide; Rats; Rats, Inbred Strains; Spiperone | 1981 |
Effect of chronic antidepressant treatment and subsequent withdrawal on [3H]-5-hydroxytryptamine and [3H]-spiperone binding in rat frontal cortex and serotonin receptor mediated behaviour.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Butyrophenones; Cerebral Cortex; Humans; Male; Metergoline; Methoxydimethyltryptamines; Rats; Receptors, Serotonin; Serotonin; Spiperone; Substance Withdrawal Syndrome | 1983 |
Schistosoma mansoni: differences in acetylcholine, dopamine, and serotonin control of circular and longitudinal parasite muscles.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Dopamine; Magnesium; Male; Metergoline; Muscle Contraction; Physostigmine; Schistosoma mansoni; Serotonin; Spiperone | 1984 |
Acute and chronic effects of serotonin (5HT) antagonists on serotonin binding sites.
Topics: Animals; Binding Sites; Cyproheptadine; Male; Metergoline; Methysergide; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Spiperone | 1983 |
Interaction of cholinergic and dopaminergic influences on yawning behavior.
Topics: Animals; Apomorphine; Behavior, Animal; Benzofurans; Citalopram; Fluoxetine; Metergoline; Physostigmine; Propylamines; Rats; Receptors, Cholinergic; Receptors, Dopamine; Scopolamine; Spiperone | 1980 |
Effects of dopamine D1-like receptor agonists on food-maintained operant behavior in rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Conditioning, Operant; Dopamine Agonists; Dopamine Antagonists; Drug Synergism; Food; Male; Metergoline; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reinforcement Schedule; Reward; Spiperone | 2006 |