Page last updated: 2024-08-16

spiperone and ketanserin

spiperone has been researched along with ketanserin in 164 studies

Research

Studies (164)

Timeframe	Studies, this research(%)	All Research%
pre-1990	73 (44.51)	18.7374
1990's	69 (42.07)	18.2507
2000's	16 (9.76)	29.6817
2010's	6 (3.66)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Newman-Tancredi, A; Strange, PG; Wootton, R	1
Amlaiky, N; Boschert, U; Hen, R; Maroteaux, L; Plassat, JL; Saudou, F	1
George, SR; Guan, HC; Laurier, LG; Ng, G; Niznik, HB; O'Dowd, BF; Seeman, P; Sunahara, RK; Torchia, J; Van Tol, HH	1
Billings, J; Kung, HF; Kung, MP; Murphy, RA	1
Billings, J; Chumpradit, S; Kung, HF; Kung, MP; Pan, S	1
Dannals, RF; Frost, JJ; Ravert, HT; Wagner, HN; Wilson, AA	1
Guo, YZ; Kasliwal, R; Kung, HF; Kung, MP; Mach, RH; Pan, SG	1
Glennon, RA; Herrick-Davis, K; Lyon, RA; Seggel, MR; Soine, WH; Titeler, M	1
Glennon, RA	2
Janssen, CG; Laduron, PM; Thijssen, JB; Van Dun, J; Wouters, W	1
Andrews, PR; Craik, DJ; Martin, JL	1
Buckingham, J; Glen, RC; Hill, AP; Hyde, RM; Martin, GR; Robertson, AD; Salmon, JA; Woollard, PM	1
Baldessarini, RJ; Booth, RG; Charifson, PS; Kula, NS; McPhail, AT; Myers, AM; Owens, CE; Wyrick, SD	1
Baez, M; Kursar, JD; Nelson, DL; Wainscott, DB	1
Adham, N; Bard, JA; Branchek, TA; Vaysse, P; Weinshank, RL; Zgombick, J	1
Kung, HF; Kung, MP; Zhuang, ZP	1
Amlaiky, N; Hen, R; Plassat, JL	1
Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB	1
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM	1
Chang, DJ; Eglen, RM; Jasper, JR; Kosaka, A; To, ZP	1
Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB	1
Egan, CT; Herrick-Davis, K; Teitler, M	1
Conklin, DS; Fitzgerald, LW; Hartig, PR; Iyer, G; Kostich, WA; Krause, CM; Largent, BL; Marshall, AP; Patterson, JP; Tran, DP	1
Booth, RG; Brown, RL; Bucholtz, EC; Tropsha, A; Wyrick, SD	1
Kristiansen, K; Kroeze, WK; Roth, BL; Shapiro, DA	1
Bach, T; Krobert, KA; Kvingedal, AM; Levy, FO; Syversveen, T	1
Itoh, H; Muramatsu, I; Taniguchi, T; Yoshio, R	1
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D	1
Berardi, F; Colabufo, NA; Contino, M; Lacivita, E; Leopoldo, M; Perrone, R	1
Cleves, AE; Jain, AN; Kirshner, D; Langham, JJ; Spitzer, R	1
Kitamura, Y; Kozaka, T; Miwa, D; Ogawa, K; Shiba, K; Uno, I	1
Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L	1
Chen, Y; Liu, BF; Liu, S; Liu, X; Qiu, Y; Wang, S; Xu, X; Yu, M; Zhang, G; Zhang, T; Zhao, S	1
Cao, X; Chen, Y; Liu, BF; Liu, X; Qiu, Y; Xu, X; Yu, M; Zhang, G; Zhang, L; Zhang, Y	1
Lepailleur, A; Rochais, C; Thirumaran, SL	1
Hyttel, J; Nielsen, JB; Nowak, G	1
Berardi, F; Daniele, E; Govoni, S; Leopoldo, M; Lograno, MD; Perrone, R; Tortorella, V	1
Jeffrey, JJ; Rydelek-Fitzgerald, L; Wilcox, BD	1
Marttila, RJ; Päivärinta, MA; Rinne, JO; Rinne, UK	1
MacLennan, SJ; Martin, GR	1
Choudhary, MS; Craigo, S; Roth, BL	1
Akaike, N; Furukawa, K; Kogure, K; Onodera, H	1
Wilcox, RE; Young, KA	1
Barker, EL; Burris, KD; Sanders-Bush, E	1
Feniuk, W; Humphrey, PP; Perren, MJ	1
Seyfried, CA; Tobler, P	1
Frau, M; Gessa, GL; Stefanini, E	1
Crick, H; Wallis, DI	1
Hirose, A; Kato, T; Katsube, J; Nakamura, M; Ohno, Y; Shimizu, H; Tanaka, H	1
Cabib, S; Kempf, E; Puglisi-Allegra, S; Schleef, C	1
Gallager, DW; Goldman-Rakic, PS; Lidow, MS; Rakic, P	1
Deshpande, SB; Warnick, JE	1
Amenta, F; Ricci, A	1
Darmani, NA; Glennon, RA; Martin, BR; Pandey, U	1
Cowen, PJ; Gartside, SE	1
Inoue, O; Kobayasi, K; Suhara, T	1
Cohen, ML; Kurz, KD; Schenck, KW	1
Dreher, JK; Jackson, DM	1
Frenken, M	1
Brazell, C; Dourish, CT; King, BH; Middlemiss, DN	1
Andersen, PH; Treiman, M	1
Brauner, V; Kalkman, HO; Neumann, V	1
Altar, CA; Marshall, JF; O'Neil, S; Walter, RJ	1
Horisaka, K; Sugimoto, Y; Yamada, J	1
Mizuta, T; Segawa, T	1
Alexander, BS; Broadhurst, AM; Wood, MD	1
Gallager, D; Goldman-Rakic, PS; Rakic, P	1
Buchman, O; Grigoriadis, DE; Niznik, HB; Pri-Bar, I; Seeman, P	1
Andree, TH; Koenig, JI; Meltzer, HY; Mikuni, M; Tong, CY	1
Greiner, HE; Haase, A; Klockow, M; Schmitges, CJ; Seyfried, C	1
Altar, CA; Neale, RF; Stone, GA; Wasley, AM	1
Baldwin, JJ; Clineschmidt, BV; Huff, JR; Lotti, VJ; Pettibone, DJ; Randall, WC; Vacca, J; Young, SD	1
Barnett, A; Chipkin, RE; Duffy, RA; Ford, D; Iorio, LC; McQuade, RD	1
Beck, SG; Clarke, WP; Goldfarb, J	1
Feniuk, W; Humphrey, PP; Perren, MJ; Watts, AD	1
Forler, C; Fozard, JR; Middlemiss, DN; Tricklebank, MD	1
De Clerck, F; Janssen, PA; Tollenaere, JP; Xhonneux, B	1
Biegon, A; Kargman, S; McEwen, BS; Snyder, L	1
Murrin, LC; Zeng, W	1
Hösli, E; Hösli, L	1
Conn, PJ; Hartig, PR; Hoffman, BJ; Sanders-Bush, E	1
Hall, H; Wedel, I	1
Leff, P; Martin, GR	1
Hanada, S; Kuno, T; Mita, T; Mizoi, Y; Nakai, H; Nishino, N; Tanaka, C; Yamadori, T	1
Gudelsky, GA; Koenig, JI; Meltzer, HY	2
Luedtke, RR; Molinoff, PB	1
Nakatsuka, I; Okuno, M; Saji, H; Shiba, K; Shimizu, H; Yokoyama, A; Yoshitake, A	1
Kellar, KJ; Stockmeier, CA	1
Ananth, US; Hauser, G; Leli, U	1
Bondy, SC; Breese, GR; Duncan, GE; Iorio, LC; Mueller, RA; Napier, TC	1
Affolter, H; Burkard, WP; Pletscher, A	1
Grigoriadis, D; Seeman, P	1
Frost, JJ; Hartig, PR; Scheffel, U; Wagner, HN	1
Gorzalka, BB; Mendelson, SD	1
Demenge, P; Feuerstein, C; Guerin, B; Mouchet, P; Silice, C	1
Nishino, N; Tanaka, C	1
Gommeren, W; Leysen, JE; Van Gompel, P	1
Manda, T; Mori, J; Nishigaki, F; Shimomura, K	1
Shearman, MS; Strange, PG	1
Barrett, VJ; Cambridge, D; Leff, P; Martin, GR	1
Hotta, I; Segawa, T; Yamawaki, S	1
Bischoff, S; Heinrich, M; Krauss, J; Sonntag, JM	1
Clancy, BM; Maayani, S; Osman, R	1
Eckols, K; Sierra, V; Uphouse, L; Williams, J	1
Ozaki, L; Stern, N; Tuck, ML	1
Laduron, PM; Leysen, JE; Van Dun, J; Wouters, W	1
Laduron, PM; Luabeya, MK; Maloteaux, JM	1
Ilien, B; Laduron, PM; Schotte, A	1
Facoory, BD; Laverty, R; Millar, JA	1
Iversen, LL; Reynolds, GP; Rossor, MN	1
Helmeste, DM; Tang, SW	1
Cheney, DL; Costa, E; Gandolfi, O; Hong, JS	1
Köhler, C	2
Finch, CE; Marcusson, JO; Morgan, DG; Winblad, B	1
Freedman, M; Hamel, L; Luttinger, D; Perrone, M; Ward, SJ	1
Battaglia, G; Shannon, M; Titeler, M	1
Biegon, A; Mann, JJ; McBride, PA; McEwen, B	1
Hayashi, T; Ichida, S; Terao, M	1
Creese, I; Hamblin, MW; Leff, SE	1
Janssen, PF; Laduron, PM; Leysen, JE	1
Canton, H; Ike, J; Sanders-Bush, E	1
García-Colunga, J; Miledi, R	1
Hartig, PR; Hoffman, BJ; Kaufman, MJ	1
Chiba, S; Vhora, S	1
Lidow, MS; Rakic, P	1
Cai, B; Ehrlich, GK; Frietze, W; Lem, G; Murphy, RB; Pan, YP; Schuster, DI; Singh, G; Stoupakis, G	1
Nowak, JZ; Zawilska, JB	1
Wallis, DI; Wang, XC; Wu, J	1
Ageel, AM; Alhaider, AA; Ginawi, OT	1
Bobker, DH	1
Damaj, MI; Glennon, RA; Martin, BR	1
Berardi, F; Colabufo, NA; Fiorentini, F; Govoni, S; Olgiati, V; Perrone, R; Tortorella, V; Vanotti, E	1
Jeffrey, JJ; Rydelek-Fitzgerald, L; Teitler, M; Wilcox, BD	2
Kagaya, A; Mikuni, M; Muraoka, S; Saitoh, K; Takahashi, K	1
Abdel-Fattah, AF; el-Hady, KA; Matsumoto, K; Watanabe, H	1
Anthony, M; Chong, BH; Srikiatkhachorn, A; Yang, M	1
Barthe, JY; Chesnoy-Marchais, D	1
Berardi, F; Giudice, G; Govoni, S; Lucchi, L; Perrone, R; Tortorella, V	1
Nishimura, Y	1
Anthony, M; Srikiatkhachorn, A	1
Ichikawa, J; Meltzer, HY; Sumiyoshi, T	1
Chiyotani, A; Konno, K; Takemura, H; Tamaoki, J	1
Balasubramanian, S; Paulose, CS	1
Chairungsrilerd, N; Furukawa, K; Kisara, K; Ohizumi, Y; Tadano, T	1
Dun, NJ; Hwang, LL	1
Aloyo, VJ; Harvey, JA; Hoffman, ME; Salt, GL	1
Fernández, F; García-Mera, X; Rodríguez, G; Urrutia, A	1
Bult, H; Geerts, IS; Herman, AG; Matthys, KE	1
Bagchi, S; Deshpande, SB	1
Dannals, RF; Finley, P; Mathews, WB; Musachio, JL; Ravert, HT; Scheffel, U	1
Chagkutip, J; Govitrapong, P; Srikiatkhachorn, A; Turakitwanakan, W	1
Bult, H; De Meyer, GR; Geerts, IS	1
Dikic, B; Kassiou, M; Katsifis, A; Mardon, K; Mattner, F	1
De los Angeles, J; Dukat, M; Glennon, RA; Herndon, J; Ismaiel, AM; Khorana, N; Metwally, K; Teitler, M	1
Bhattacharya, SK; Khanna, VK; Kumar, V; Seth, PK; Singh, PN	1
Abel, PW; Bockman, CS; O'Donohue, HA	1
Kost, NV; Pryanikova, NA; Ryukert, EN; Sokolov, OY; Zolotarev, YA; Zozulya, AA	1
Deshpande, SB; Gupta, R; Singh, JN	1
Baumeister, AA; Hawkins, MF; Hearn, JK; Uzelac, SM	1
Bae, YM; Cho, H; Kim, B; Kim, JG; Noh, HJ; Park, SW; Sung, DJ	1

Reviews

6 review(s) available for spiperone and ketanserin

Article	Year
Central serotonin receptors as targets for drug research. Journal of medicinal chemistry, 1987, Volume: 30, Issue:1 Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin	1987
The role of receptor binding in drug discovery. Journal of natural products, 1993, Volume: 56, Issue:4 Topics: Animals; Drug Design; Humans; Receptors, Drug	1993
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7). Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14 Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists	2003
Structure-activity relationships of serotonin 5-HT European journal of medicinal chemistry, 2019, Dec-01, Volume: 183 Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship	2019
Effects of electroconvulsive shock and serotonin axon lesions on beta-adrenergic and serotonin-2 receptors in rat brain. Annals of the New York Academy of Sciences, 1986, Volume: 462 Topics: Anesthetics; Animals; Axons; Brain; Cerebral Cortex; Cyclic AMP; Dihydroalprenolol; Electroconvulsive Therapy; Frontal Lobe; Hippocampus; Ketanserin; Norepinephrine; Piperidines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Muscarinic; Receptors, Serotonin; Serotonin; Spiperone; Stress, Physiological; Time Factors; Tritium	1986
Ketanserin and spiperone as templates for novel serotonin 5-HT(2A) antagonists. Current topics in medicinal chemistry, 2002, Volume: 2, Issue:6 Topics: Animals; Drug Design; Isoquinolines; Ketanserin; Piperidines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Structure-Activity Relationship	2002

Other Studies

158 other study(ies) available for spiperone and ketanserin

Article	Year
High-level stable expression of recombinant 5-HT1A 5-hydroxytryptamine receptors in Chinese hamster ovary cells. The Biochemical journal, 1992, Aug-01, Volume: 285 ( Pt 3) Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Binding, Competitive; Blotting, Northern; Cattle; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Gene Expression; Guanosine Triphosphate; Hippocampus; Humans; Receptors, Serotonin; Recombinant Proteins; Tetrahydronaphthalenes; Transfection	1992
Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers. Proceedings of the National Academy of Sciences of the United States of America, 1992, Apr-01, Volume: 89, Issue:7 Topics: 3T3 Cells; Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Cerebellum; Corpus Striatum; Gene Expression; Genes; GTP-Binding Proteins; Mice; Molecular Sequence Data; Nucleic Acid Hybridization; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Purkinje Cells; Receptors, Serotonin; RNA, Messenger; Serotonin	1992
Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1. Nature, 1991, Apr-18, Volume: 350, Issue:6319 Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain; Cell Line; Cell Membrane; Cloning, Molecular; Dopamine; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Oligonucleotide Probes; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D5; RNA, Messenger; Sequence Homology, Nucleic Acid; Transfection	1991
Synthesis and characterization of iodobenzamide analogues: potential D-2 dopamine receptor imaging agents. Journal of medicinal chemistry, 1990, Volume: 33, Issue:1 Topics: Animals; Benzofurans; Binding, Competitive; Chemical Phenomena; Chemistry; Corpus Striatum; Iodine Radioisotopes; Isotope Labeling; Male; Molecular Structure; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Tissue Distribution	1990
(+/-)-7-chloro-8-hydroxy-1-(4'-[125I]iodophenyl)-3-methyl-2,3,4,5- tetrahydro-1H-3-benzazepine: a potential CNS D-1 dopamine receptor imaging agent. Journal of medicinal chemistry, 1989, Volume: 32, Issue:7 Topics: Animals; Benzazepines; Brain; Chemical Phenomena; Chemistry; Humans; Iodobenzoates; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Tissue Distribution	1989
Synthesis and biological evaluation of [125I]- and [123I]-4-iododexetimide, a potent muscarinic cholinergic receptor antagonist. Journal of medicinal chemistry, 1989, Volume: 32, Issue:5 Topics: Animals; Dexetimide; Iodine Radioisotopes; Isotope Labeling; Male; Mice; Parasympatholytics; Piperidines; Receptors, Muscarinic; Tomography, Emission-Computed	1989
Dopamine D-2 receptor imaging radiopharmaceuticals: synthesis, radiolabeling, and in vitro binding of (R)-(+)- and (S)-(-)-3-iodo-2-hydroxy-6-methoxy-N- [(1-ethyl-2-pyrrolidinyl)methyl]benzamide. Journal of medicinal chemistry, 1988, Volume: 31, Issue:5 Topics: Animals; Benzamides; Chemical Phenomena; Chemistry; Corpus Striatum; In Vitro Techniques; Iodine Radioisotopes; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship	1988
[125I]-1-(2,5-dimethoxy-4-iodophenyl)-2-amino-propane: an iodinated radioligand that specifically labels the agonist high-affinity state of 5-HT2 serotonin receptors. Journal of medicinal chemistry, 1988, Volume: 31, Issue:1 Topics: Amphetamines; Indicators and Reagents; Iodine Radioisotopes; Kinetics; Radioligand Assay; Receptors, Serotonin	1988
In vitro labeling of serotonin-S2 receptors: synthesis and binding characteristics of [3H]-7-aminoketanserin. Journal of medicinal chemistry, 1986, Volume: 29, Issue:9 Topics: Animals; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Frontal Lobe; Guinea Pigs; Ketanserin; Kinetics; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin	1986
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Computer-aided design and synthesis of 5-substituted tryptamines and their pharmacology at the 5-HT1D receptor: discovery of compounds with potential anti-migraine properties. Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18 Topics: Animals; Aorta; Computer-Aided Design; Drug Design; Haplorhini; In Vitro Techniques; Migraine Disorders; Models, Chemical; Rabbits; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Saphenous Vein; Serotonin Receptor Agonists; Structure-Activity Relationship; Tryptamines	1995
Conformational analysis, pharmacophore identification, and comparative molecular field analysis of ligands for the neuromodulatory sigma 3 receptor. Journal of medicinal chemistry, 1994, Nov-25, Volume: 37, Issue:24 Topics: Animals; Ligands; Models, Molecular; Molecular Conformation; Receptors, sigma; Rodentia; Structure-Activity Relationship; Tetrahydronaphthalenes	1994
Molecular cloning, functional expression, and mRNA tissue distribution of the human 5-hydroxytryptamine2B receptor. Molecular pharmacology, 1994, Volume: 46, Issue:2 Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; DNA, Complementary; Humans; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Tissue Distribution	1994
Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase. The Journal of biological chemistry, 1993, Nov-05, Volume: 268, Issue:31 Topics: Adenylyl Cyclases; Base Sequence; Cloning, Molecular; DNA Primers; Humans; Molecular Sequence Data; Receptors, Serotonin; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction	1993
Synthesis of (R,S)-trans-8-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)amino]tetral in (trans-8-OH-PIPAT): a new 5-HT1A receptor ligand. Journal of medicinal chemistry, 1993, Oct-15, Volume: 36, Issue:21 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Iodine Radioisotopes; Ligands; Rats; Receptors, Serotonin; Stereoisomerism; Tetrahydronaphthalenes; Tritium	1993
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Molecular pharmacology, 1993, Volume: 44, Issue:2 Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists	1993
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor. Molecular pharmacology, 1993, Volume: 43, Issue:3 Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature	1993
Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b). British journal of pharmacology, 1997, Volume: 122, Issue:1 Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Humans; Molecular Sequence Data; Placenta; Radioligand Assay; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid	1997
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1 Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine	1998
Creation of a constitutively activated state of the 5-hydroxytryptamine2A receptor by site-directed mutagenesis: inverse agonist activity of antipsychotic drugs. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1 Topics: Animals; Antipsychotic Agents; COS Cells; Mutagenesis, Site-Directed; Phosphatidylinositols; Protein Conformation; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship	1998
High-affinity agonist binding correlates with efficacy (intrinsic activity) at the human serotonin 5-HT2A and 5-HT2C receptors: evidence favoring the ternary complex and two-state models of agonist action. Journal of neurochemistry, 1999, Volume: 72, Issue:5 Topics: Amphetamines; Binding, Competitive; Cell Line; Ergolines; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydrolysis; Isomerism; Ligands; Models, Biological; Phosphatidylinositols; Receptors, Serotonin; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone	1999
Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors. Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16 Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes	1999
Differential modes of agonist binding to 5-hydroxytryptamine(2A) serotonin receptors revealed by mutation and molecular modeling of conserved residues in transmembrane region 5. Molecular pharmacology, 2000, Volume: 58, Issue:5 Topics: Amino Acid Substitution; Animals; Binding, Competitive; Conserved Sequence; COS Cells; DOM 2,5-Dimethoxy-4-Methylamphetamine; Hydrolysis; Membrane Proteins; Models, Molecular; Mutagenesis, Site-Directed; Phosphatidylinositols; Protein Folding; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Signal Transduction; Tryptamines	2000
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution. Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:6 Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Brain; Cell Line; Cloning, Organism; Genetic Variation; Humans; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution	2001
Affinity of serotonin receptor antagonists and agonists to recombinant and native alpha1-adrenoceptor subtypes. Japanese journal of pharmacology, 2001, Volume: 86, Issue:2 Topics: Animals; Aorta, Thoracic; Carotid Arteries; Dogs; Humans; Male; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists	2001
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2 Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists	2004
Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. 2. Journal of medicinal chemistry, 2007, Aug-23, Volume: 50, Issue:17 Topics: Amides; Animals; Cell Line; Guinea Pigs; Humans; Ileum; Male; Muscle Contraction; Muscle, Smooth; Piperazines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship; Tetrahydronaphthalenes	2007
Physical binding pocket induction for affinity prediction. Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19 Topics: Binding Sites; Ligands; Models, Molecular; Neural Networks, Computer; Peptide Fragments; Protein Binding; Receptor, Serotonin, 5-HT1A	2009
Syntheses and in vitro evaluation of decalinvesamicol analogues as potential imaging probes for vesicular acetylcholine transporter (VAChT). Bioorganic & medicinal chemistry, 2012, Aug-15, Volume: 20, Issue:16 Topics: Animals; Male; Molecular Structure; Piperidines; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, sigma; Vesicular Acetylcholine Transport Proteins	2012
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells. Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6 Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship	2013
Synthesis and biological investigation of coumarin piperazine (piperidine) derivatives as potential multireceptor atypical antipsychotics. Journal of medicinal chemistry, 2013, Jun-13, Volume: 56, Issue:11 Topics: Animals; Antipsychotic Agents; Avoidance Learning; Biological Availability; Coumarins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; In Vitro Techniques; Isoxazoles; Lethal Dose 50; Mice; Motor Activity; Prolactin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Dopamine D3; Structure-Activity Relationship; Weight Gain	2013
Synthesis and Biological Evaluation of Fused Tricyclic Heterocycle Piperazine (Piperidine) Derivatives As Potential Multireceptor Atypical Antipsychotics. Journal of medicinal chemistry, 2018, 11-21, Volume: 61, Issue:22 Topics: Animals; Antipsychotic Agents; Body Weight; Chemistry Techniques, Synthetic; Drug Design; Ether-A-Go-Go Potassium Channels; Heterocyclic Compounds; Memory; Mice; Piperazine; Rats; Schizophrenia; Structure-Activity Relationship; Tissue Distribution	2018
The acute effect of sertindole on brain 5-HT2, D2 and alpha 1 receptors (ex vivo radioreceptor binding studies). Journal of neural transmission. General section, 1992, Volume: 89, Issue:1-2 Topics: Animals; Brain Chemistry; Dose-Response Relationship, Drug; Imidazoles; Indoles; Ketanserin; Male; Prazosin; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin; Spiperone	1992
Oxygen isosteric derivatives of 3-(3-hydroxyphenyl)-N-n-propylpiperidine. Journal of medicinal chemistry, 1992, Aug-07, Volume: 35, Issue:16 Topics: Animals; Brain; Dopamine Agents; In Vitro Techniques; Ketanserin; Mice; Oxygen; Piperidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone	1992
Regulation of collagenase gene expression by serotonin and progesterone in rat uterine smooth muscle cells. The Journal of biological chemistry, 1992, Oct-15, Volume: 267, Issue:29 Topics: Amphetamines; Animals; Cell Nucleus; Cells, Cultured; Collagenases; DNA Probes; Female; Gene Expression Regulation, Enzymologic; Ketanserin; Kinetics; Muscle, Smooth; Myometrium; Progesterone; Quipazine; Rats; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Spiperone; Tetradecanoylphorbol Acetate; Transcription, Genetic; Uterus	1992
Decrease in mesencephalic dopamine autoreceptors in experimental herpes simplex encephalitis. Journal of neural transmission. General section, 1992, Volume: 89, Issue:1-2 Topics: Animals; Brain; Corpus Striatum; Encephalitis; Female; Herpes Simplex; Ketanserin; Male; Mesencephalon; Motor Activity; Rabbits; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone	1992
Effect of the thromboxane A2-mimetic U46619 on 5-HT1-like and 5-HT2 receptor-mediated contraction of the rabbit isolated femoral artery. British journal of pharmacology, 1992, Volume: 107, Issue:2 Topics: Animals; Biphenyl Compounds; Femoral Artery; Heptanoic Acids; In Vitro Techniques; Ketanserin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Prostaglandin Endoperoxides, Synthetic; Rabbits; Receptors, Serotonin; Serotonin; Spiperone; Thromboxane A2; Vasoconstriction	1992
Identification of receptor domains that modify ligand binding to 5-hydroxytryptamine2 and 5-hydroxytryptamine1c serotonin receptors. Molecular pharmacology, 1992, Volume: 42, Issue:4 Topics: Base Sequence; Binding, Competitive; Ergolines; Haloperidol; In Vitro Techniques; Ketanserin; Molecular Sequence Data; Oligodeoxyribonucleotides; Receptors, Serotonin; Recombinant Fusion Proteins; Spiperone; Structure-Activity Relationship; Transfection	1992
Expression of 5-HT3 receptors in PC12 cells treated with NGF and 8-Br-cAMP. Journal of neurophysiology, 1992, Volume: 67, Issue:4 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cations, Monovalent; Cell Membrane; Dose-Response Relationship, Drug; Indoles; Ketanserin; Kinetics; Membrane Potentials; Nerve Growth Factors; PC12 Cells; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone; Time Factors; Tropisetron	1992
Characterization of D2 receptors and dopamine levels in the thalamus of the rat. Life sciences, 1991, Volume: 48, Issue:19 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Homovanillic Acid; Ketanserin; Kinetics; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Spiperone; Synaptic Transmission; Thalamus	1991
Phosphoinositide hydrolysis linked 5-HT2 receptors in fibroblasts from choroid plexus. Brain research, 1991, Jun-28, Volume: 552, Issue:2 Topics: Animals; Cells, Cultured; Choroid Plexus; DOM 2,5-Dimethoxy-4-Methylamphetamine; Fibroblasts; Haloperidol; Hydrolysis; Inositol Phosphates; Ketanserin; Lysergic Acid Diethylamide; Male; Mianserin; Phosphatidylinositols; Prazosin; Rabbits; Receptors, Serotonin; Serotonin; Spiperone	1991
Vascular 5-HT1-like receptors that mediate contraction of the dog isolated saphenous vein and carotid arterial vasoconstriction in anaesthetized dogs are not of the 5-HT1A or 5-HT1D subtype. British journal of pharmacology, 1991, Volume: 102, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Atropine; Carotid Arteries; Dogs; Ganglionic Blockers; In Vitro Techniques; Indoles; Ketanserin; Methiothepin; Muscle, Smooth, Vascular; Pyrilamine; Receptors, Serotonin; Saphenous Vein; Spiperone; Sulfonamides; Sumatriptan; Tetrahydronaphthalenes; Vasoconstriction; Vasoconstrictor Agents	1991
Total versus unspecific binding: standardization and optimization of receptor-ligand binding assays. Drug metabolism and drug interactions, 1991, Volume: 9, Issue:2 Topics: Animals; Binding, Competitive; Brain; Filtration; Imidazoles; Indoles; Ketanserin; Ligands; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone	1991
Increase in D2 dopamine receptors in the substantia nigra after chronic (-)-sulpiride treatment. Brain research, 1991, Aug-02, Volume: 555, Issue:2 Topics: Animals; Caudate Nucleus; Ketanserin; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Substantia Nigra; Sulpiride; Up-Regulation	1991
Inhibition of reflex responses of neonate rat lumbar spinal cord by 5-hydroxytryptamine. British journal of pharmacology, 1991, Volume: 103, Issue:3 Topics: Animals; Animals, Newborn; Citalopram; Electrodes; Female; Ketanserin; Ligands; Rats; Reflex; Reflex, Monosynaptic; Serotonin; Serotonin Antagonists; Spinal Cord; Spiperone	1991
Pharmacological actions of SM-9018, a new neuroleptic drug with both potent 5-hydroxytryptamine2 and dopamine2 antagonistic actions. Japanese journal of pharmacology, 1990, Volume: 53, Issue:3 Topics: Animals; Antipsychotic Agents; Behavior, Animal; Brain Chemistry; Catalepsy; Dopamine Antagonists; Indoles; Isoindoles; Ketanserin; Male; Methamphetamine; Mice; Mice, Inbred Strains; Motor Activity; Norepinephrine; Parasympatholytics; Psychomotor Performance; Rats; Rats, Inbred Strains; Serotonin Antagonists; Spiperone; Stereotyped Behavior; Thiazoles	1990
Repeated stressful experiences differently affect brain dopamine receptor subtypes. Life sciences, 1991, Volume: 48, Issue:13 Topics: Animals; Benzazepines; Brain; Dopamine Antagonists; Ketanserin; Kinetics; Male; Mice; Mice, Inbred Strains; Nucleus Accumbens; Receptors, Dopamine; Spiperone; Stress, Physiological; Tritium	1991
Distribution of dopaminergic receptors in the primate cerebral cortex: quantitative autoradiographic analysis using [3H]raclopride, [3H]spiperone and [3H]SCH23390. Neuroscience, 1991, Volume: 40, Issue:3 Topics: Animals; Benzazepines; Brain Mapping; Cerebral Cortex; Ketanserin; Macaca mulatta; Mianserin; Raclopride; Receptors, Dopamine; Salicylamides; Species Specificity; Spiperone	1991
Interaction of thyrotropin-releasing hormone and methysergide on the monosynaptic reflex in isolated mammalian spinal cord. Neuroscience letters, 1990, Aug-14, Volume: 116, Issue:1-2 Topics: 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Cyproheptadine; Drug Interactions; In Vitro Techniques; Indoles; Ketanserin; Male; Methysergide; Rats; Rats, Inbred Strains; Reflex; Serotonin Antagonists; Spinal Cord; Spiperone; Synapses; Thyrotropin-Releasing Hormone; Tropisetron	1990
Autoradiographic localization of dopamine DA-2 receptor sites in rat mesenteric vascular tree. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2 Topics: Animals; Autoradiography; Binding Sites; Hydroxydopamines; Ketanserin; Male; Mesenteric Arteries; Oxidopamine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Sympathectomy	1990
Do functional relationships exist between 5-HT1A and 5-HT2 receptors? Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Ketanserin; Male; Methoxydimethyltryptamines; Mice; Mice, Inbred ICR; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Stereoisomerism; Tetrahydronaphthalenes	1990
Mediation of ACTH and prolactin responses to 5-HTP by 5-HT2 receptors. European journal of pharmacology, 1990, Apr-10, Volume: 179, Issue:1-2 Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Animals; Dose-Response Relationship, Drug; Ketanserin; Male; Metergoline; Piperidines; Prolactin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiperone	1990
Effect of desipramine on dopamine receptor binding in vivo. Life sciences, 1990, Volume: 47, Issue:23 Topics: Animals; Antidepressive Agents, Tricyclic; Benzazepines; Cerebellum; Corpus Striatum; Desipramine; Dose-Response Relationship, Drug; In Vitro Techniques; Ketanserin; Male; Mice; Receptors, Dopamine; Spiperone	1990
5-HT2-receptor antagonists: alpha 1- vs. 5-HT2-receptor blocking properties in blood vessels. Journal of cardiovascular pharmacology, 1988, Volume: 11 Suppl 1 Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Ergolines; Ketanserin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phentolamine; Piperidines; Pyrimidinones; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiperone	1988
Role of D1 and D2 dopamine receptors in mediating locomotor activity elicited from the nucleus accumbens of rats. Brain research, 1989, May-22, Volume: 487, Issue:2 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Ketanserin; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reserpine; Septal Nuclei; Spiperone; Time Factors	1989
Evidence for two populations of 5-hydroxytryptamine receptors in dog basilar artery. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1 Topics: Animals; Basilar Artery; Cocaine; Dogs; In Vitro Techniques; Indomethacin; Ketanserin; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Potassium; Prazosin; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Spiperone; Vasoconstriction	1989
MK-212 increases rat plasma ACTH concentration by activation of the 5-HT1C receptor subtype. Neuroscience letters, 1989, Oct-23, Volume: 105, Issue:1-2 Topics: Adrenocorticotropic Hormone; Animals; Antiparkinson Agents; Ergolines; Ketanserin; Male; Metergoline; Pindolol; Piperazines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone	1989
Two classes of [3H]spiperone binding sites in bovine neurohypophysis: D-2 receptors and putative 5-HT2 receptors. Journal of receptor research, 1989, Volume: 9, Issue:4-5 Topics: Animals; Antipsychotic Agents; Binding, Competitive; Cattle; Ketanserin; Least-Squares Analysis; Pituitary Gland, Posterior; Radioligand Assay; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Spiperone	1989
Supersensitivity of atherosclerotic rabbit aorta to ergometrine is mediated by 5-HT2 receptors. The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:12 Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Body Weight; Cyproheptadine; Ergonovine; In Vitro Techniques; Ketanserin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Rabbits; Receptors, Serotonin; Spiperone	1989
Brain dopamine and serotonin receptor sites revealed by digital subtraction autoradiography. Science (New York, N.Y.), 1985, May-03, Volume: 228, Issue:4699 Topics: Animals; Autoradiography; Brain; Butaclamol; Computers; Ketanserin; Piperidines; Radiographic Image Enhancement; Radionuclide Imaging; Rats; Receptors, Dopamine; Receptors, Serotonin; Spiperone; Sulpiride	1985
The evidence for the involvement of the 5-HT1A receptor in 5-HT syndrome induced in mice by tryptamine. Japanese journal of pharmacology, 1989, Volume: 51, Issue:3 Topics: Animals; Behavior, Animal; Haloperidol; Ketanserin; Male; Methysergide; Mice; Mice, Inbred DBA; Propranolol; Receptors, Serotonin; Serotonin; Spiperone; Tryptamines	1989
Chronic effects of imipramine and lithium on 5-HT receptor subtypes in rat frontal cortex, hippocampus and choroid plexus: quantitative receptor autoradiographic analysis. Japanese journal of pharmacology, 1989, Volume: 50, Issue:3 Topics: Animals; Autoradiography; Brain Chemistry; Cerebral Cortex; Choroid Plexus; Hippocampus; Imipramine; Iodine Radioisotopes; Ketanserin; Lithium; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone	1989
Heterogeneous 3H-rauwolscine binding sites in rat cortex: two alpha 2-adrenoceptor subtypes or an additional non-adrenergic interaction? Life sciences, 1988, Volume: 43, Issue:1 Topics: Animals; Binding Sites; Binding, Competitive; Cerebral Cortex; Creatinine; Dioxanes; Drug Combinations; Hippocampus; Ketanserin; Male; Methysergide; Phentolamine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Spiperone; Spiro Compounds; Yohimbine	1988
Quantitative autoradiography of major neurotransmitter receptors in the monkey striate and extrastriate cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:10 Topics: Animals; Autoradiography; Cerebral Cortex; Clonidine; Female; Flunitrazepam; Ketanserin; Macaca mulatta; Male; Muscimol; Pindolol; Prazosin; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Neurotransmitter; Serotonin; Spiperone; Visual Cortex	1988
Dopamine D2 receptors selectively labeled by a benzamide neuroleptic: [3H]-YM-09151-2. Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 329, Issue:4 Topics: Animals; Antipsychotic Agents; Benzamides; Binding, Competitive; Corpus Striatum; Dogs; Guanylyl Imidodiphosphate; Ketanserin; Kinetics; Piperidines; Receptors, Dopamine; Sodium; Spiperone; Substrate Specificity; Tetrahydronaphthalenes	1985
Differential effect of subchronic treatment with various neuroleptic agents on serotonin2 receptors in rat cerebral cortex. Journal of neurochemistry, 1986, Volume: 46, Issue:1 Topics: 5,7-Dihydroxytryptamine; Animals; Antipsychotic Agents; Cerebral Cortex; Chlorpromazine; Clozapine; Female; Haloperidol; Imipramine; Ketanserin; Loxapine; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Sulpiride	1986
Studies on the receptor profile of bisoprolol. Arzneimittel-Forschung, 1986, Volume: 36, Issue:2 Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Bisoprolol; Cattle; Dihydroalprenolol; Domperidone; Humans; In Vitro Techniques; Ketanserin; Male; Piperidines; Prazosin; Propanolamines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Histamine; Receptors, Muscarinic; Spiperone; Tetrahydronaphthalenes; Yohimbine	1986
Typical and atypical antipsychotic occupancy of D2 and S2 receptors: an autoradiographic analysis in rat brain. Brain research bulletin, 1986, Volume: 16, Issue:4 Topics: Animals; Antipsychotic Agents; Autoradiography; Binding, Competitive; Brain; Caudate Nucleus; Haloperidol; Ketanserin; Kinetics; Male; Nucleus Accumbens; Olfactory Bulb; Piperidines; Putamen; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Spiperone	1986
Pharmacological profile of a new potent and specific alpha 2-adrenoceptor antagonist, L-657,743. Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:2 Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Binding, Competitive; Blood Platelets; Cattle; Cerebral Cortex; Clonidine; Humans; In Vitro Techniques; Ketanserin; Male; Prazosin; Quinolizines; Radioligand Assay; Rats; Rats, Inbred Strains; Serotonin; Spiperone; Vas Deferens	1987
Serotonergic component of SCH 23390: in vitro and in vivo binding analyses. Life sciences, 1988, Volume: 43, Issue:23 Topics: Animals; Antipsychotic Agents; Benzazepines; Binding, Competitive; Brain; Corpus Striatum; Dopamine Antagonists; Frontal Lobe; Ketanserin; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Spiperone; Stereoisomerism; Structure-Activity Relationship	1988
Spiperone differentiates multiple 5-hydroxytryptamine responses in rat hippocampal slices in vitro. European journal of pharmacology, 1985, Oct-08, Volume: 116, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Butyrophenones; Hippocampus; In Vitro Techniques; Ketanserin; Piperidines; Rats; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes	1985
A comparison of 5-hydroxytryptamine receptors mediating contraction in rabbit aorta and dog saphenous vein: evidence for different receptor types obtained by use of selective agonists and antagonists. British journal of pharmacology, 1985, Volume: 86, Issue:3 Topics: Animals; Aorta; Dogs; In Vitro Techniques; Ketanserin; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Piperidines; Rabbits; Receptors, Serotonin; Saphenous Vein; Serotonin; Serotonin Antagonists; Spiperone	1985
Subtypes of the 5-HT receptor mediating the behavioural responses to 5-methoxy-N,N-dimethyltryptamine in the rat. European journal of pharmacology, 1985, Oct-29, Volume: 117, Issue:1 Topics: Animals; Apomorphine; Behavior, Animal; Betaxolol; Haloperidol; Ketanserin; Male; Pindolol; Piperidines; Prazosin; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reserpine; Spiperone	1985
Dependence of the antagonism at human platelet 5-HT2 receptors by ketanserin on the reaction pH. Thrombosis research, 1985, Dec-01, Volume: 40, Issue:5 Topics: Amidines; Blood Platelets; Butyrophenones; Cyproheptadine; Female; Humans; Hydrogen-Ion Concentration; Ketanserin; Kinetics; Male; Piperidines; Platelet Aggregation; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone	1985
Characterization and localization of serotonin receptors in human brain postmortem. Brain research, 1986, Jan-15, Volume: 363, Issue:1 Topics: Adult; Aged; Autoradiography; Binding, Competitive; Diencephalon; Female; Frontal Lobe; Hippocampus; Humans; Ketanserin; Male; Middle Aged; Piperidines; Receptors, Serotonin; Spiperone; Telencephalon	1986
Postnatal ontogeny of dopamine D2 receptors in rat striatum. Biochemical pharmacology, 1986, Apr-01, Volume: 35, Issue:7 Topics: Age Factors; Animals; Animals, Newborn; Corpus Striatum; Ketanserin; Kinetics; Mathematics; Piperidines; Rats; Receptors, Dopamine; Spiperone	1986
Binding sites for [3H]dopamine and dopamine-antagonists on cultured astrocytes of rat striatum and spinal cord: an autoradiographic study. Neuroscience letters, 1986, Apr-11, Volume: 65, Issue:2 Topics: Animals; Astrocytes; Autoradiography; Binding Sites; Cells, Cultured; Corpus Striatum; Domperidone; Dopamine; Dopamine Antagonists; Flupenthixol; Ketanserin; Piperidines; Rats; Spinal Cord; Spiperone; Stereoisomerism; Tritium	1986
A unique serotonin receptor in choroid plexus is linked to phosphatidylinositol turnover. Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:11 Topics: Animals; Cerebral Cortex; Choroid Plexus; In Vitro Techniques; Ketanserin; Mianserin; Phosphatidylinositols; Piperidines; Rats; Receptors, Serotonin; Spiperone	1986
Comparisons between the in vitro binding of two substituted benzamides and two butyrophenones to dopamine-D2 receptors in the rat striatum. Acta pharmacologica et toxicologica, 1986, Volume: 58, Issue:5 Topics: Animals; Benzamides; Butyrophenones; Corpus Striatum; Domperidone; In Vitro Techniques; Ketanserin; Kinetics; Male; Piperidines; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Salicylamides; Spiperone; Sulpiride	1986
Peripheral 5-HT2-like receptors. Can they be classified with the available antagonists? British journal of pharmacology, 1986, Volume: 88, Issue:3 Topics: Animals; Aorta, Thoracic; In Vitro Techniques; Jugular Veins; Ketanserin; Male; Methysergide; Piperidines; Rabbits; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone; Trazodone	1986
Decreased serotonin S2 and increased dopamine D2 receptors in chronic schizophrenics. Biological psychiatry, 1986, Volume: 21, Issue:14 Topics: Adult; Aged; Caudate Nucleus; Chronic Disease; Female; Frontal Lobe; Humans; Ketanserin; Male; Middle Aged; Radioligand Assay; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Schizophrenia; Spiperone	1986
Thermoregulatory responses to serotonin (5-HT) receptor stimulation in the rat. Evidence for opposing roles of 5-HT2 and 5-HT1A receptors. Neuropharmacology, 1986, Volume: 25, Issue:12 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature Regulation; Ketanserin; Male; Methoxydimethyltryptamines; Pindolol; Piperidines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes	1986
Stimulation of corticosterone and beta-endorphin secretion in the rat by selective 5-HT receptor subtype activation. European journal of pharmacology, 1987, May-07, Volume: 137, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; beta-Endorphin; Corticosterone; Endorphins; Ketanserin; Male; Pindolol; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Tetrahydronaphthalenes	1987
Characterization of binding sites for [3H]spiroperidol. Biochemical pharmacology, 1987, Oct-01, Volume: 36, Issue:19 Topics: Animals; Binding Sites; Caudate Nucleus; Chromatography, Ion Exchange; Digitonin; Dogs; In Vitro Techniques; Ketanserin; Kinetics; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Tritium	1987
In vitro evaluation of radioiodinated butyrophenones as radiotracer for dopamine receptor study. Life sciences, 1987, Oct-26, Volume: 41, Issue:17 Topics: Animals; Binding, Competitive; Butyrophenones; Cell Membrane; Corpus Striatum; Female; Iodine Radioisotopes; Ketanserin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Spiperone	1987
Stimulation of phosphoinositide hydrolysis by serotonin in C6 glioma cells. Journal of neurochemistry, 1987, Volume: 48, Issue:1 Topics: Animals; Cell Line; Glioma; Hydrolysis; Inositol; Inositol Phosphates; Ketanserin; Lithium; Phosphates; Phosphatidylinositol Phosphates; Phosphatidylinositols; Rats; Serotonin; Spiperone	1987
6-hydroxydopamine treatments enhance behavioral responses to intracerebral microinjection of D1- and D2-dopamine agonists into nucleus accumbens and striatum without changing dopamine antagonist binding. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Behavior, Animal; Benzazepines; Corpus Striatum; Dopamine; Dopamine Antagonists; Ergolines; Female; Hydroxydopamines; Injections, Intraventricular; Ketanserin; Microinjections; Motor Activity; Nucleus Accumbens; Oxidopamine; Pregnancy; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Septal Nuclei; Spiperone	1987
Verapamil, an antagonist at 5-hydroxytryptamine receptors of human blood platelets. European journal of pharmacology, 1985, Jan-22, Volume: 108, Issue:2 Topics: Adenosine Diphosphate; Binding, Competitive; Blood Platelets; Cerebral Cortex; Gallopamil; Humans; In Vitro Techniques; Ketanserin; Membranes; Piperidines; Receptors, Serotonin; Spiperone; Verapamil	1985
Complete conversion of brain D2 dopamine receptors from the high- to the low-affinity state for dopamine agonists, using sodium ions and guanine nucleotide. Journal of neurochemistry, 1985, Volume: 44, Issue:6 Topics: Animals; Apomorphine; Brain; Guanine Nucleotides; In Vitro Techniques; Ketanserin; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sodium; Spiperone; Tetrahydronaphthalenes; Tritium	1985
In vivo binding of 125I-LSD to serotonin 5-HT2 receptors in mouse brain. Life sciences, 1985, Aug-19, Volume: 37, Issue:7 Topics: Animals; Binding, Competitive; Brain; Cinanserin; Ketanserin; Lysergic Acid Diethylamide; Mianserin; Mice; Piperidines; Receptors, Serotonin; Spiperone; Time Factors; Tissue Distribution	1985
A facilitatory role for serotonin in the sexual behavior of the female rat. Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:6 Topics: Animals; Castration; Estradiol; Female; Ketanserin; Methysergide; Piperidines; Progesterone; Quipazine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Sexual Behavior, Animal; Spiperone	1985
Changes of the striatal 3H-spiperone binding 3-6 weeks after nigrostriatal denervation and after two years. Life sciences, 1985, Sep-09, Volume: 37, Issue:10 Topics: Animals; Butyrophenones; Corpus Striatum; Denervation; Haloperidol; Hydroxydopamines; Ketanserin; Kinetics; Male; Oxidopamine; Piperidines; Rats; Rats, Inbred Strains; Spiperone; Substantia Nigra; Time Factors	1985
Target size analysis of serotonin 5-HT1 and 5-HT2 receptors in bovine brain membranes. Life sciences, 1985, Sep-23, Volume: 37, Issue:12 Topics: Animals; Binding, Competitive; Brain Chemistry; Cattle; Caudate Nucleus; Cerebral Cortex; Freeze Drying; Ketanserin; Molecular Weight; Piperidines; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone; Synaptic Membranes	1985
The dissociation rate of unlabelled drugs from receptor sites: a poorly investigated, yet important aspect in receptor research. Studies on the serotonin-S2 receptor. Journal of receptor research, 1988, Volume: 8, Issue:1-4 Topics: Animals; Binding, Competitive; Female; Frontal Lobe; Ketanserin; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Spiperone	1988
Important role of serotonin in the antitumor effects of recombinant human tumor necrosis factor-alpha in mice. Cancer research, 1988, Aug-01, Volume: 48, Issue:15 Topics: Animals; Cell Survival; Cyproheptadine; Female; Fibrosarcoma; Ketanserin; Mice; Mice, Inbred BALB C; Receptors, Serotonin; Recombinant Proteins; Serotonin; Serotonin Antagonists; Spiperone; Tumor Necrosis Factor-alpha	1988
Guanine nucleotide effects on agonist binding to serotonin 5HT2 receptors in rat frontal cortex. Biochemical pharmacology, 1988, Aug-15, Volume: 37, Issue:16 Topics: Animals; Cerebral Cortex; Guanine Nucleotides; Guanosine Triphosphate; Ketanserin; Kinetics; Magnesium; Male; Rats; Receptors, Serotonin; Spiperone	1988
Comparative analysis of two types of 5-hydroxytryptamine receptor mediating vasorelaxation: differential classification using tryptamines. Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:4 Topics: Animals; Endothelium, Vascular; In Vitro Techniques; Ketanserin; Male; Pentobarbital; Rabbits; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone; Tryptamines; Vasodilation	1987
Long-term lithium treatment causes serotonin receptor down-regulation via serotonergic presynapses in rat brain. Neuropsychobiology, 1986, Volume: 16, Issue:1 Topics: 5-Hydroxytryptophan; Animals; Brain; Frontal Lobe; Head; Hippocampus; In Vitro Techniques; Ketanserin; Lithium; Male; Methiothepin; Muscle Contraction; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Time Factors	1986
The D-1 dopamine receptor antagonist SCH 23390 also interacts potently with brain serotonin (5-HT2) receptors. European journal of pharmacology, 1986, Oct-07, Volume: 129, Issue:3 Topics: Animals; Benzazepines; Brain; In Vitro Techniques; Ketanserin; Male; Rats; Receptors, Dopamine; Receptors, Serotonin; Spiperone; Tissue Distribution	1986
Kinetics of competitive drug action at 5-hydroxytryptamine2 receptors in isolated rabbit aorta. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1 Topics: Animals; Aorta; Binding, Competitive; Diffusion; Indoles; Ketanserin; Kinetics; Male; Methysergide; Muscle, Smooth, Vascular; Rabbits; Receptors, Serotonin; Serotonin; Spiperone; Tryptamines	1987
Variations in binding of [3H]5-HT to cortical membranes during the female rat estrous cycle. Brain research, 1986, Sep-03, Volume: 381, Issue:2 Topics: Animals; Binding Sites; Estrus; Female; Frontal Lobe; In Vitro Techniques; Ketanserin; Rats; Rats, Inbred F344; Receptors, Serotonin; Serotonin; Spiperone	1986
Evidence for dopaminergic binding sites in the human adrenal cortex. Metabolism: clinical and experimental, 1986, Volume: 35, Issue:12 Topics: Adrenal Cortex; Adult; Aged; Apomorphine; Binding, Competitive; Bromocriptine; Domperidone; Dopamine; Epinephrine; Female; Humans; Ketanserin; Male; Metoclopramide; Middle Aged; Receptors, Dopamine; Spiperone; Sulpiride; Time Factors	1986
Differential photoaffinity labelling of serotonin-S2 receptors and histamine-H1 receptors using 7-azidoketanserin. FEBS letters, 1985, Mar-25, Volume: 182, Issue:2 Topics: Affinity Labels; Animals; Azides; Binding, Competitive; Butyrophenones; Cerebellum; Cerebral Cortex; Female; Guinea Pigs; Ketanserin; Photolysis; Piperidines; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Serotonin; Spiperone	1985
Regional and cortical laminar distributions of serotonin S2, benzodiazepine, muscarinic, and dopamine D2 receptors in human brain. Journal of neurochemistry, 1984, Volume: 43, Issue:4 Topics: Adult; Aged; Brain; Cerebral Cortex; Diazepam; Humans; Ketanserin; Male; Middle Aged; Piperidines; Quinuclidinyl Benzilate; Receptors, Cell Surface; Receptors, Dopamine; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Serotonin; Spiperone; Tissue Distribution	1984
Solubilized serotonin receptors from rat and dog brain. Selective labelling with [3H]ketanserin. FEBS letters, 1982, Feb-22, Volume: 138, Issue:2 Topics: Animals; Antipsychotic Agents; Binding, Competitive; Brain; Butyrophenones; Dogs; Isonipecotic Acids; Ketanserin; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Solubility; Species Specificity; Spiperone; Time Factors	1982
Mechanism of action of ketanserin. Lancet (London, England), 1982, Nov-20, Volume: 2, Issue:8308 Topics: Animals; Antihypertensive Agents; Humans; Ketanserin; Muscle Contraction; Muscle, Smooth, Vascular; Piperidines; Rats; Receptors, Serotonin; Serotonin Antagonists; Spiperone	1982
Preliminary studies of human cortical 5-HT2 receptors and their involvement in schizophrenia and neuroleptic drug action. Journal of neural transmission. Supplementum, 1983, Volume: 18 Topics: Antipsychotic Agents; Cerebral Cortex; Humans; Ketanserin; Piperidines; Receptors, Serotonin; Schizophrenia; Spiperone; Substrate Specificity	1983
Unusual acute effects of antidepressants and neuroleptics on S2-serotonergic receptors. Life sciences, 1983, Dec-19, Volume: 33, Issue:25 Topics: Amoxapine; Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Fenclonine; Frontal Lobe; Ketanserin; Loxapine; Male; Mianserin; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone	1983
On the neurotoxicity of chlordecone: a role for gamma-aminobutyric acid and serotonin. Brain research, 1984, Jun-11, Volume: 303, Issue:1 Topics: Acetylcholine; Animals; Binding Sites; Brain; Chlordecone; gamma-Aminobutyric Acid; Insecticides; Ketanserin; Male; Mianserin; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Spiperone	1984
Autoradiographic mapping of spirodecanone binding-sites in the hippocampal region of the rat. Evidence for a localization on intrinsic neurons. Neuroscience letters, 1984, May-04, Volume: 46, Issue:2 Topics: Animals; Autoradiography; Binding, Competitive; Brain Mapping; Butyrophenones; Haloperidol; Hippocampus; Ketanserin; Male; Mianserin; Piperidines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Dopamine; Serotonin; Spiperone; Tetrahydronaphthalenes	1984
Serotonin-2 binding sites in human frontal cortex and hippocampus. Selective loss of S-2A sites with age. Brain research, 1984, Oct-08, Volume: 311, Issue:1 Topics: Adolescent; Adult; Aged; Aging; Cerebral Cortex; Hippocampus; Humans; Ketanserin; Kinetics; Methysergide; Middle Aged; Organ Specificity; Piperidines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone	1984
The effects of serotonin antagonists in a behavioral despair procedure in mice. European journal of pharmacology, 1984, Dec-15, Volume: 107, Issue:1 Topics: Animals; Behavior, Animal; Cyproheptadine; Guinea Pigs; Ketanserin; Male; Methysergide; Mice; Muscle, Smooth; Piperidines; Pizotyline; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone; Trazodone; Tritium	1984
Guanine nucleotides modulate cortical S2 serotonin receptors. Journal of receptor research, 1984, Volume: 4, Issue:7 Topics: Animals; Binding, Competitive; Cerebral Cortex; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Ketanserin; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone	1984
The distribution of serotonin binding sites in the hippocampal region of the rat brain. An autoradiographic study. Neuroscience, 1984, Volume: 13, Issue:3 Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Hippocampus; Ketanserin; Male; Methoxydimethyltryptamines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone	1984
Characterization of serotonin binding sites on human platelets. Life sciences, 1983, Nov-14, Volume: 33, Issue:20 Topics: Adult; Binding, Competitive; Blood Platelets; Frontal Lobe; Humans; Ketanserin; Male; Piperidines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone	1983
Selective inhibition by ketanserin and spiroperidol of 5-HT-induced myometrial contraction. European journal of pharmacology, 1983, Dec-09, Volume: 96, Issue:1-2 Topics: Animals; Butyrophenones; Estradiol; Female; Ketanserin; Ovary; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Spiperone; Uterine Contraction	1983
Interactions of agonists with D-2 dopamine receptors: evidence for a single receptor population existing in multiple agonist affinity-states in rat striatal membranes. Biochemical pharmacology, 1984, Mar-15, Volume: 33, Issue:6 Topics: Animals; Binding, Competitive; Butyrophenones; Corpus Striatum; Domperidone; Dopamine Antagonists; Guanine Nucleotides; Ketanserin; Metoclopramide; Piperidines; Radioligand Assay; Rats; Receptors, Dopamine; Sodium; Spiperone; Temperature	1984
In vivo binding of [3H]ketanserin on serotonin S2-receptors in rat brain. European journal of pharmacology, 1982, Jun-16, Volume: 81, Issue:1 Topics: Animals; Brain; Ketanserin; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Tritium	1982
Developmental switch in the hippocampal serotonin receptor linked to phosphoinositide hydrolysis. Brain research, 1995, Apr-24, Volume: 678, Issue:1-2 Topics: Age Factors; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Hippocampus; Hydrolysis; Inositol Phosphates; Ketanserin; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; RNA, Messenger; Spiperone	1995
Effects of serotonergic agents on neuronal nicotinic acetylcholine receptors. Proceedings of the National Academy of Sciences of the United States of America, 1995, Mar-28, Volume: 92, Issue:7 Topics: Animals; Cells, Cultured; Electric Conductivity; Female; Ketanserin; Membrane Potentials; Methysergide; Neurons; Oocytes; Patch-Clamp Techniques; Rats; Receptors, Nicotinic; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Tetrahydronaphthalenes; Xenopus laevis	1995
Serotonin 5-HT2C receptor stimulates cyclic GMP formation in choroid plexus. Journal of neurochemistry, 1995, Volume: 64, Issue:1 Topics: Animals; Cattle; Choroid Plexus; Cyclic GMP; Ketanserin; Mianserin; Phosphatidylinositols; Receptors, Serotonin; Spiperone; Swine	1995
Functional 5-HT receptor subtypes in the isolated canine common carotid artery. Heart and vessels, 1994, Volume: 9, Issue:5 Topics: Adrenergic alpha-Antagonists; Animals; Carotid Artery, Common; Diltiazem; Dogs; Female; Ketanserin; Male; Methysergide; Norepinephrine; Potassium Chloride; Quinazolines; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Spiperone; Vasoconstriction	1994
Distribution and density of monoamine receptors in the primate visual cortex devoid of retinal input from early embryonic stages. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:3 Pt 2 Topics: Animals; Anophthalmos; Benzazepines; Clonidine; Eye Enucleation; Gene Expression Regulation, Developmental; Gestational Age; Ketanserin; Macaca mulatta; Pindolol; Prazosin; Radioligand Assay; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Spiperone; Visual Cortex; Visual Pathways	1995
N-(1-arylpropionyl)-4-aryltetrahydropyridines, a new class of high-affinity selective sigma receptor ligands. Journal of medicinal chemistry, 1993, Nov-26, Volume: 36, Issue:24 Topics: Animals; Antipsychotic Agents; Binding Sites; Binding, Competitive; Cattle; Cerebellum; Dihydropyridines; Haloperidol; Ketanserin; Propiophenones; Pyridines; Radioligand Assay; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, sigma; Spiperone	1993
Dopamine receptor regulating serotonin N-acetyltransferase activity in chick retina represents a D4-like subtype: pharmacological characterization. Neurochemistry international, 1994, Volume: 24, Issue:3 Topics: Animals; Arylamine N-Acetyltransferase; Benzamides; Benzazepines; Chickens; Circadian Rhythm; Clozapine; Dopamine; Dopamine Antagonists; Ergolines; Ketanserin; Male; Quinpirole; Receptors, Dopamine; Retina; Spiperone; Sulpiride	1994
Is 5-hydroxytryptamine mediating descending inhibition in the neonatal rat spinal cord through different receptor subtypes? European journal of pharmacology, 1993, Dec-21, Volume: 250, Issue:3 Topics: Animals; Animals, Newborn; Citalopram; Dioxanes; Dopamine Antagonists; Electric Stimulation; Ketanserin; Lumbar Vertebrae; Methiothepin; Methysergide; Rats; Receptors, Serotonin; Reflex, Monosynaptic; Serotonin; Spinal Cord; Spinal Nerve Roots; Spiperone; Spiro Compounds; Sulpiride; Sumatriptan	1993
The quipazine- and TFMPP-increased conditioned avoidance response in rats: role of 5HT1C/5-HT2 receptors. Neuropharmacology, 1993, Volume: 32, Issue:12 Topics: Animals; Avoidance Learning; Conditioning, Operant; Ketanserin; Male; Mianserin; Nadolol; Pindolol; Piperazines; Prazosin; Quipazine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reference Values; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Tropanes	1993
A slow excitatory postsynaptic potential mediated by 5-HT2 receptors in nucleus prepositus hypoglossi. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:4 Topics: Amphetamines; Animals; Brain Stem; Cyclohexane Monoterpenes; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Ketanserin; Male; Medulla Oblongata; Membrane Potentials; Neurons; Pindolol; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sumatriptan; Synaptic Transmission	1994
Involvement of the serotonergic system in the hypoactive and antinociceptive effects of nicotine in mice. Brain research bulletin, 1994, Volume: 33, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Ketanserin; Locomotion; Male; Mice; Mice, Inbred ICR; Nicotine; Nociceptors; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone	1994
Mixed 5-HT1A/D-2 activity of a new model of arylpiperazines: 1-aryl-4-[3-(1,2-dihydronaphthalen-4-yl)-n-propyl]piperazines. 1. Synthesis and structure-activity relationships. Journal of medicinal chemistry, 1994, Jan-07, Volume: 37, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cell Membrane; Cerebral Cortex; Corpus Striatum; Ketanserin; Male; Molecular Structure; Naphthalenes; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Serotonin; Spiperone; Structure-Activity Relationship; Tritium	1994
Serotonin-mediated 5-HT2 receptor gene regulation in rat myometrial smooth muscle cells. Molecular and cellular endocrinology, 1993, Volume: 92, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Biguanides; Cells, Cultured; Cycloheximide; Female; Gene Expression Regulation; Ketanserin; Medroxyprogesterone Acetate; Myometrium; Piperazines; Quipazine; Rats; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sulpiride; Transcription, Genetic; Up-Regulation	1993
Serotonin-dependent collagenase induction in rat myometrial smooth muscle cells: mediation by the 5-HT2 receptor. Molecular and cellular endocrinology, 1993, Volume: 91, Issue:1-2 Topics: Amphetamines; Animals; Base Sequence; Blotting, Northern; Collagenases; Female; Iodine Radioisotopes; Ketanserin; Molecular Sequence Data; Myometrium; Polymerase Chain Reaction; Rats; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Receptor Agonists; Spiperone	1993
Dexamethasone potentiates serotonin-2 receptor-mediated intracellular Ca2+ mobilization in C6 glioma cells. Neuroendocrinology, 1993, Volume: 57, Issue:2 Topics: Amphetamines; Animals; Calcium; Dexamethasone; Glioma; Ketanserin; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Tumor Cells, Cultured	1993
5-HT1A and 5-HT2 receptors mediate hypo- and hyperthermic effects of tryptophan in pargyline-pretreated rats. Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:2 Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Body Temperature; Dopamine Antagonists; Fenclonine; Ketanserin; Male; Monoamine Oxidase Inhibitors; Pargyline; Pindolol; Propranolol; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Spiperone; Tryptophan	1995
Serotonin stimulates megakaryocytopoiesis via the 5-HT2 receptor. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1996, Volume: 7, Issue:2 Topics: Animals; Blood Platelets; Cell Line; Erythropoietin; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Interleukin-3; Interleukin-6; Ketanserin; Megakaryocytes; Mice; Mice, Inbred BALB C; Platelet-Derived Growth Factor; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone; Thrombin	1996
Voltage-dependent block of NMDA responses by 5-HT agonists in ventral spinal cord neurones. British journal of pharmacology, 1996, Volume: 117, Issue:1 Topics: Animals; Cells, Cultured; Dopamine Antagonists; Dose-Response Relationship, Drug; Ketanserin; Magnesium; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Spinal Cord; Spiperone	1996
Novel potent sigma 1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives. Journal of medicinal chemistry, 1996, Oct-11, Volume: 39, Issue:21 Topics: Animals; Hippocampus; Ketanserin; Phencyclidine; Piperidines; Rats; Receptors, Phencyclidine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, sigma; Spiperone; Structure-Activity Relationship; Tetrahydronaphthalenes	1996
Characterization of 5-hydroxytryptamine receptors mediating contractions in basilar arteries from stroke-prone spontaneously hypertensive rats. British journal of pharmacology, 1996, Volume: 117, Issue:6 Topics: Animals; Basilar Artery; Dose-Response Relationship, Drug; In Vitro Techniques; Ketanserin; Male; Methiothepin; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Serotonin; Serotonin; Serotonin Agents; Spiperone	1996
Serotonin receptor adaptation in patients with analgesic-induced headache. Cephalalgia : an international journal of headache, 1996, Volume: 16, Issue:6 Topics: Adolescent; Adult; Aged; Analgesics; Blood Platelets; Female; Headache; Humans; Ketanserin; Male; Middle Aged; Migraine Disorders; Neuronal Plasticity; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Spiperone; Substance-Related Disorders; Up-Regulation	1996
The effect of streptozotocin-induced diabetes on dopamine2, serotonin1A and serotonin2A receptors in the rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1997, Volume: 16, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Diabetes Mellitus, Experimental; Dopamine Antagonists; Frontal Lobe; Haloperidol; Hippocampus; Ketanserin; Male; Neostriatum; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Streptozocin	1997
5-Hydroxytryptamine inhibits Na absorption and stimulates Cl secretion across canine tracheal epithelial sheets. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1997, Volume: 27, Issue:8 Topics: Amiloride; Animals; Chloride Channels; Chlorine; Diuretics; Dogs; Dopamine Antagonists; Electric Conductivity; Electric Stimulation; Epithelium; Female; In Vitro Techniques; Ion Channel Gating; Ketanserin; Male; Membrane Potentials; Ondansetron; Serotonin; Serotonin Antagonists; Sodium; Sodium Channels; Spiperone; Trachea	1997
Induction of DNA synthesis in primary cultures of rat hepatocytes by serotonin: possible involvement of serotonin S2 receptor. Hepatology (Baltimore, Md.), 1998, Volume: 27, Issue:1 Topics: Animals; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Hepatectomy; Ketanserin; Liver; Liver Regeneration; Male; Membrane Proteins; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone	1998
Effect of gamma-mangostin through the inhibition of 5-hydroxy-tryptamine2A receptors in 5-fluoro-alpha-methyltryptamine-induced head-twitch responses of mice. British journal of pharmacology, 1998, Volume: 123, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Injections, Intraventricular; Inositol Phosphates; Ketanserin; Male; Mice; Motor Activity; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Tryptamines; Xanthenes; Xanthones	1998
5-Hydroxytryptamine responses in immature rat rostral ventrolateral medulla neurons in vitro. Journal of neurophysiology, 1998, Volume: 80, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dopamine Antagonists; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine Diphosphate; Ketanserin; Medulla Oblongata; Membrane Potentials; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Synaptic Transmission; Thionucleotides	1998
Agonist and antagonist binding to rabbit cortical 5-HT2A receptors: opposite effects of magnesium. Annals of the New York Academy of Sciences, 1998, Dec-15, Volume: 861 Topics: Amphetamines; Animals; Cerebral Cortex; Fluorobenzenes; Guanylyl Imidodiphosphate; Ketanserin; Magnesium; Methysergide; Piperidines; Prazosin; Rabbits; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone	1998
New hexahydrocarbazoles and spiro indoles, and their affinity for D2 dopamine and 5-HT2A serotonin receptors. Chemical & pharmaceutical bulletin, 1999, Volume: 47, Issue:7 Topics: Animals; Antipsychotic Agents; Binding, Competitive; Carbazoles; Dopamine Antagonists; In Vitro Techniques; Indoles; Ketanserin; Neostriatum; Prefrontal Cortex; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin Antagonists; Spiperone	1999
Involvement of 5-HT1B receptors in collar-induced hypersensitivity to 5-hydroxytryptamine of the rabbit carotid artery. British journal of pharmacology, 1999, Volume: 127, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Braces; Carotid Arteries; Dose-Response Relationship, Drug; Hypersensitivity; In Vitro Techniques; Ketanserin; Male; Methysergide; Oxadiazoles; Piperazines; Potassium Chloride; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sumatriptan; Tryptamines; Vasoconstriction	1999
Indian red scorpion (Buthus tamulus) venom-induced augmentation of cardiac reflexes is mediated through the involvement of peripheral 5-HT3 and central 5-HT1A receptor subtypes. Toxicon : official journal of the International Society on Toxinology, 1999, Volume: 37, Issue:12 Topics: Animals; Biguanides; Blood Pressure; Central Nervous System; Heart; Heart Rate; Injections, Intravenous; Ketanserin; Ondansetron; Peripheral Nervous System; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT3; Reflex; Scorpion Venoms; Scorpions; Serotonin Receptor Agonists; Spiperone; Vagus Nerve	1999
[11C]-methyl 4-[(3,4-dichlorophenyl)acetyl]-3-[(1-pyrrolidinyl)-methyl]-1- piperazinecarboxylate ([11C]GR89696): synthesis and in vivo binding to kappa opiate receptors. Nuclear medicine and biology, 1999, Volume: 26, Issue:7 Topics: Animals; Benzeneacetamides; Binding, Competitive; Brain; Carbon Radioisotopes; Dopamine Antagonists; Isotope Labeling; Ketanserin; Mice; Piperazines; Pyrrolidines; Radiopharmaceuticals; Receptors, Opioid, kappa; Serotonin Antagonists; Spiperone; Tissue Distribution	1999
Platelet 5-HT(2A) receptors in schizophrenic patients with and without neuroleptic treatment. Psychiatry research, 2000, Sep-25, Volume: 96, Issue:1 Topics: Adult; Antipsychotic Agents; Blood Platelets; Case-Control Studies; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Flupenthixol; Humans; Ketanserin; Male; Phenothiazines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Risperidone; Schizophrenia; Serotonin Antagonists; Spiperone	2000
Collar-induced elevation of mRNA and functional activity of 5-HT(1B) receptor in the rabbit carotid artery. British journal of pharmacology, 2000, Volume: 131, Issue:8 Topics: Animals; Blotting, Western; Carotid Arteries; Constriction; Dose-Response Relationship, Drug; Gene Expression Regulation; In Vitro Techniques; Ketanserin; Male; Potassium Chloride; Rabbits; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin Antagonists; Spiperone; Vasoconstriction	2000
Pharmacological evaluation of (+)-2- [123I]A-69024: a radioligand for in vivo studies of dopamine D1 receptors. Life sciences, 2001, Jun-29, Volume: 69, Issue:6 Topics: Animals; Benzazepines; Brain; Cerebellum; Clozapine; Corpus Striatum; Dopamine Antagonists; Haloperidol; Injections, Intravenous; Iodine Radioisotopes; Ketanserin; Ligands; Male; Papaverine; Rats; Rats, Wistar; Receptors, Dopamine D1; Spiperone; Stereoisomerism; Tetrahydroisoquinolines; Tetrahydronaphthalenes; Tissue Distribution; Tomography, Emission-Computed, Single-Photon	2001
Brain neurotransmitter receptor binding and nootropic studies on Indian Hypericum perforatum Linn. Phytotherapy research : PTR, 2002, Volume: 16, Issue:3 Topics: Amnesia; Animals; Avoidance Learning; Behavior, Animal; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Electroshock; Female; Flunitrazepam; Hypericum; Ketanserin; Male; Maze Learning; Nootropic Agents; Phytotherapy; Piracetam; Plant Extracts; Rats; Receptors, Neurotransmitter; Spiperone; Tritium	2002
Pharmacological properties of serotonin receptor subtypes mediating contraction of bovine inferior alveolar arteries. Archives of oral biology, 2004, Volume: 49, Issue:3 Topics: Alveolar Process; Animals; Arteries; Cattle; Dose-Response Relationship, Drug; Endothelium, Vascular; Ketanserin; Mandible; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone; Vasoconstriction	2004
Reactions between beta-casomorphins-7 and 5-HT2-serotonin receptors. Bulletin of experimental biology and medicine, 2005, Volume: 140, Issue:5 Topics: Animals; Cattle; Cerebral Cortex; Dopamine Antagonists; Dose-Response Relationship, Drug; Endorphins; Humans; Inhibitory Concentration 50; Ketanserin; Peptide Fragments; Platelet Aggregation; Protein Binding; Rats; Receptors, Serotonin, 5-HT2; Serotonin Antagonists; Spiperone	2005
Ptychodiscus brevis toxin-induced depression of spinal reflexes involves 5-HT via 5-HT3 receptors modulated by NMDA receptor. Neuroscience letters, 2006, Nov-27, Volume: 409, Issue:1 Topics: Animals; Biguanides; Depression, Chemical; Dinoflagellida; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Ketanserin; Male; Marine Toxins; Neurotoxins; Ondansetron; Oxocins; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin, 5-HT3; Reflex; Serotonin; Serotonin Antagonists; Spinal Cord; Spinal Nerve Roots; Spiperone	2006
Effects of selective serotonin2 ligands on behaviors evoked by stress in the rat. Pharmacology, biochemistry, and behavior, 2008, Volume: 90, Issue:4 Topics: Animals; Behavior, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Ketanserin; Male; Motor Activity; Pain Measurement; Postural Balance; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT2; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Stress, Psychological; Vocalization, Animal	2008
Serotonin contracts the rat mesenteric artery by inhibiting 4-aminopyridine-sensitive Kv channels via the 5-HT2A receptor and Src tyrosine kinase. Experimental & molecular medicine, 2013, Dec-13, Volume: 45 Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Ketanserin; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nifedipine; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Spiperone; src-Family Kinases; Vasoconstriction	2013