spiperone has been researched along with kainic acid in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (77.14) | 18.7374 |
| 1990's | 7 (20.00) | 18.2507 |
| 2000's | 1 (2.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Emson, PC; Minneman, KP; Quik, M | 1 |
| Emson, PC; Joyce, E; Quik, M | 1 |
| Freed, WJ; Neckers, LM; Perlow, MJ; Rosenblatt, JE; Shore, D; Wyatt, RJ | 1 |
| Minneman, KP; Molinoff, PB; Zahniser, NR | 1 |
| Creese, I; Snyder, SH; Usdin, T | 1 |
| Fibiger, HC; Nagy, JI; Reisine, TD; Yamamura, HI | 1 |
| Leysen, JE | 1 |
| Agnati, LF; Fuxe, K; Gustafsson, JA; Schwarcz, R | 1 |
| Fields, JZ; Reisine, TD; Yamamura, HI | 1 |
| Kikuchi, T; Nakata, Y; Segawa, T; Zhang, X | 1 |
| De Montigny, C; Debonnel, G; Junien, JL; Monnet, FP | 1 |
| Nagy, JI; Van der Kooy, D; Weinreich, P | 1 |
| Hawthorn, M; Hruska, RE; Skattebøl, A; Triggle, DJ | 1 |
| Csernansky, JG; Glick, S; Mellentin, J | 1 |
| Fahn, S; Hassan, M; Jackson-Lewis, V; Traub, M; Wagner, HR | 1 |
| Concas, A; Porceddu, ML | 1 |
| Fuxe, K; Goldstein, M; Hökfelt, T; Schwarcz, R; Terenius, L | 1 |
| Dowling, JE; Emson, PC; Iversen, LL; Quik, M; Watling, KJ | 1 |
| Innanen, VT; McGeer, EG; McGeer, PL | 1 |
| Jenner, P; Marsden, CD; Reavill, C; Theodorou, A | 1 |
| Schallert, T; Upchurch, M; Vaughn, DM; Wilcox, RE | 1 |
| Randall, PK; Severson, JA | 1 |
| Korf, J; Sebens, JB; Van der Werf, JF; Van het Schip, F | 1 |
| Carboni, E; Memo, M; Spano, PF | 1 |
| Gommeren, W; Leysen, JE; Van Gompel, P | 1 |
| Adams, L; Creese, I; Hyttel, J; Leff, S | 1 |
| Cross, AJ; Waddington, JL | 1 |
| Fresia, P; Memo, M; Spano, PF; Stefanini, E; Trabucchi, M | 1 |
| Seeman, P; Weinreich, P | 1 |
| Kanazawa, I; Kimura, M; Murata, M | 1 |
| Aoki, H; Jian, Z; Kogure, K; Onodera, H; Yae, T | 1 |
| Bardgett, ME; Csernansky, JG; Jackson, JL; Taylor, GT | 1 |
| Fosbraey, P; Kitchen, I; Ridd, MJ | 1 |
| Thoreson, WB; Tranchina, D; Witkovsky, P | 1 |
2 review(s) available for spiperone and kainic acid
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
Kainic acid and neurotransmitter interactions in the basal ganglia.
Topics: Animals; Axons; Basal Ganglia; Dendrites; Dopamine; Drug Interactions; Humans; Kainic Acid; Nerve Endings; Neurotransmitter Agents; Pyrrolidines; Quinuclidinyl Benzilate; Spiperone; Substantia Nigra | 1980 |
33 other study(ies) available for spiperone and kainic acid
| Article | Year |
|---|---|
Receptor-linked cyclic AMP systems in rat neostriatum: differential localization revealed by kainic acid injection.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Choline O-Acetyltransferase; Corpus Striatum; Cyclic AMP; Dopamine; Etorphine; Glutamate Decarboxylase; Kainic Acid; Male; Pyrrolidines; Rats; Receptors, Drug; Receptors, Opioid; Spiperone; Tyrosine 3-Monooxygenase | 1978 |
Dissociation between the presynaptic dopamine-sensitive adenylate cyclase and [3H]spiperone binding sites in rat substantia nigra.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adenylyl Cyclases; Animals; Butyrophenones; Corpus Striatum; Dopamine; Glutamate Decarboxylase; Hydroxydopamines; Kainic Acid; Male; Rats; Receptors, Dopamine; Spiperone; Substantia Nigra; Tetrahydronaphthalenes; Tyrosine 3-Monooxygenase | 1979 |
Effects of chronic haloperidol on caudate 3H-spiroperidol binding in lesioned rats.
Topics: Animals; Butaclamol; Butyrophenones; Caudate Nucleus; Cerebral Cortex; Haloperidol; Kainic Acid; Rats; Receptors, Dopamine; Spiperone | 1979 |
Persistence of beta-adrenergic receptors in rat striatum following kainic acid administration.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Choline O-Acetyltransferase; Corpus Striatum; Cyclic AMP; Dopamine; Glutamate Decarboxylase; Isoproterenol; Kainic Acid; Male; Pyrrolidines; Quinuclidinyl Benzilate; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Dopamine; Spiperone | 1979 |
Guanine nucleotides distinguish between two dopamine receptors.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Corpus Striatum; Dopamine; Guanosine Triphosphate; Kainic Acid; Kinetics; Rats; Receptors, Dopamine; Spiperone | 1979 |
Localization of dopamine receptors in rat brain.
Topics: Animals; Brain Mapping; Butaclamol; Corpus Striatum; Hydroxydopamines; Kainic Acid; Male; Neural Pathways; Rats; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Spiperone; Substantia Nigra | 1979 |
Unitary dopaminergic receptor composed of cooperatively linked agonist and antagonist sub-unit binding sites.
Topics: Animals; Apomorphine; Binding Sites; Corpus Striatum; Female; Haloperidol; Hydroxydopamines; Kainic Acid; Kinetics; Rats; Receptors, Dopamine; Spiperone; Subcellular Fractions | 1979 |
Effects of bromocriptine on 3H-spiroperidol binding sites in rat striatum. Evidence for actions of dopamine receptors not linked to adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Bromocriptine; Butyrophenones; Caudate Nucleus; Cerebral Cortex; Kainic Acid; Male; Putamen; Rats; Receptors, Dopamine; Spiperone | 1978 |
Loss of striatal dopaminergic receptors after intrastriatal kainic acid injection.
Topics: Animals; Corpus Striatum; Kainic Acid; Pyrrolidines; Rats; Receptors, Dopamine; Receptors, Muscarinic; Spiperone | 1978 |
Interactions of 7-[3-(4-[2,3-dimethylphenyl]piperazinyl)-propoxy]-2(1H)-quinolinone binding in rat striatum: effects of lesions.
Topics: Animals; Benzazepines; Binding, Competitive; Corpus Striatum; Dopamine Agents; Hydroxydopamines; In Vitro Techniques; Kainic Acid; Male; Medial Forebrain Bundle; Oxidopamine; Piperazines; Quinolones; Rats; Rats, Inbred Strains; Spiperone | 1990 |
N-methyl-D-aspartate-induced neuronal activation is selectively modulated by sigma receptors.
Topics: Animals; Aspartic Acid; Guanidines; Haloperidol; In Vitro Techniques; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Spiperone | 1990 |
Dopamine and opiate receptors: localization in the striatum and evidence for their axoplasmic transport in the nigrostriatal and striatonigral pathways.
Topics: Animals; Autoradiography; Axonal Transport; Corpus Striatum; Etorphine; Hydroxydopamines; Kainic Acid; Male; Nerve Crush; Neural Pathways; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Spiperone; Substantia Nigra | 1986 |
Kainic acid lesions decrease striatal dopamine receptors and 1,4-dihydropyridine sites.
Topics: Animals; Binding Sites; Calcium Channels; Choline O-Acetyltransferase; Corpus Striatum; Dihydropyridines; Ion Channels; Kainic Acid; Male; Nimodipine; Rats; Receptors, Dopamine; Receptors, Nicotinic; Spiperone | 1988 |
Differential effects of proglumide on mesolimbic and nigrostriatal dopamine function.
Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Glutamine; Haloperidol; Kainic Acid; Kinetics; Limbic System; Male; Proglumide; Rats; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Substantia Nigra | 1987 |
The effects of chronic bromocriptine treatment on behaviour and dopamine receptor binding in the rat striatum.
Topics: Animals; Apomorphine; Bromocriptine; Corpus Striatum; Hydroxydopamines; Kainic Acid; Male; Motor Activity; Muscle Denervation; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Substantia Nigra | 1985 |
Partial protection by CDP-choline against kainic acid-induced lesion in the rat caudate nucleus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Choline; Cytidine Diphosphate Choline; Dopamine; Kainic Acid; Levodopa; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Time Factors | 1985 |
Effects of chronic striatal kainate lesions on some dopaminergic parameters and enkephalin immunoreactive neurons in the basal ganglia.
Topics: Animals; Basal Ganglia; Choline O-Acetyltransferase; Corpus Striatum; Dopamine; Endorphins; Enkephalins; Fluorescent Antibody Technique; Kainic Acid; Male; Neurons; Pyrrolidines; Rats; Spiperone; Tyrosine 3-Monooxygenase | 1980 |
Further evidence for the existence of multiple receptors for dopamine in the central nervous system.
Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Brain; Carps; Dopamine Antagonists; Hydroxydopamines; Kainic Acid; Receptors, Dopamine; Retina; Spiperone | 1980 |
Kainic acid lesions of striatum and decortication reduce specific [3H]sulpiride binding in rats, so D-2 receptors exist post-synaptically on corticostriate afferents and striatal neurons.
Topics: Animals; Binding Sites; Cerebral Cortex; Corpus Striatum; Decerebrate State; Female; Hydroxydopamines; Kainic Acid; Kinetics; Neurons, Afferent; Pyrrolidines; Rats; Spiperone; Sulpiride | 1981 |
Posture-independent sensorimotor analysis of inter-hemispheric receptor asymmetries in neostriatum.
Topics: Animals; Apomorphine; Brain; Corpus Striatum; Dopamine; Forelimb; Functional Laterality; Hydroxydopamines; Kainic Acid; Male; Motor Activity; Oxidopamine; Posture; Radius; Rats; Receptors, Dopamine; Spiperone; Substantia Nigra; Ulna | 1983 |
Localization of [3H]N-propylnorapomorphine binding in mouse striatum.
Topics: Afferent Pathways; Animals; Apomorphine; Corpus Striatum; Frontal Lobe; Hydroxydopamines; Kainic Acid; Kinetics; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neurons; Oxidopamine; Receptors, Dopamine; Spiperone | 1983 |
Quantification of in vivo spiperone binding in the rat striatum after lesions produced by kainate or decortication.
Topics: Animals; Butyrophenones; Cerebral Cortex; Corpus Striatum; Decerebrate State; Hydroxydopamines; Kainic Acid; Kinetics; Male; Oxidopamine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone | 1984 |
Differential affinity of dopaminergic agonists and antagonists for D1 and D2 dopamine receptors in rat striatum.
Topics: Adenylyl Cyclases; Animals; Corpus Striatum; Dopamine; Dopamine Antagonists; Kainic Acid; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone | 1983 |
Demonstration of a complex subunit composition of a unitary dopamine receptor: effects of lesions and proteolytic enzymes on stereospecific binding.
Topics: Animals; Buffers; Chemical Phenomena; Chemistry; Corpus Striatum; Female; Kainic Acid; Kinetics; Ligands; Membranes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereoisomerism; Trypsin | 1983 |
Kainate lesion dissociates striatal dopamine receptor radioligand binding sites.
Topics: Animals; Apomorphine; Benzimidazoles; Corpus Striatum; Domperidone; Flupenthixol; In Vitro Techniques; Kainic Acid; Male; Piperidines; Pyrrolidines; Radioligand Assay; Rats; Receptors, Dopamine; Spiperone | 1981 |
Kainic acid lesions dissociate [3H] spiperone and [3H]cis-flupenthixol binding sites in rat striatum.
Topics: Animals; Binding Sites; Butyrophenones; Corpus Striatum; Flupenthixol; Glutamate Decarboxylase; Kainic Acid; Male; Pyrrolidines; Rats; Receptors, Dopamine; Spiperone; Thioxanthenes; Tritium | 1981 |
Detection of multiple receptors for dopamine.
Topics: Adenylyl Cyclases; Animals; Brain; Brain Mapping; Butyrophenones; Corpus Striatum; Dopamine; Kainic Acid; Kinetics; Rats; Receptors, Dopamine; Spiperone; Sulpiride | 1980 |
Effect of kainic acid on striatal dopamine receptors.
Topics: Animals; Apomorphine; Corpus Striatum; Kainic Acid; Male; Pyrrolidines; Rats; Receptors, Dopamine; Spiperone | 1980 |
Roles of dopamine and its receptors in generation of choreic movements.
Topics: Afferent Pathways; Animals; Brain Mapping; Cerebral Cortex; Choline O-Acetyltransferase; Chorea; Corpus Striatum; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Levodopa; Macaca; Neurons; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Substantia Nigra; Synapses; Tyrosine 3-Monooxygenase | 1993 |
Neural grafting to ischemic CA1 lesions in the rat hippocampus: an autoradiographic study.
Topics: Acetylcholinesterase; Animals; Autoradiography; Brain Ischemia; Brain Tissue Transplantation; Fetal Tissue Transplantation; Hippocampus; Kainic Acid; Ligands; Male; Muscimol; Naloxone; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Puromycin; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Neurotransmitter; Spiperone; Stereotaxic Techniques; Up-Regulation | 1993 |
Kainic acid decreases hippocampal neuronal number and increases dopamine receptor binding in the nucleus accumbens: an animal model of schizophrenia.
Topics: Animals; Brain Mapping; Caudate Nucleus; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Motor Activity; Nerve Degeneration; Neural Pathways; Nucleus Accumbens; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Schizophrenia; Spiperone; Temporal Lobe; Up-Regulation | 1995 |
The effect of acute kainic acid treatment on dopamine D2 receptors in rat brain.
Topics: Animals; Brain; Iodine Radioisotopes; Isotope Labeling; Kainic Acid; Male; Neurons; Protein Binding; Raclopride; Rats; Rats, Wistar; Receptors, Dopamine D2; Salicylamides; Spiperone; Sulpiride; Tritium | 1998 |
Kinetics of synaptic transfer from rods and cones to horizontal cells in the salamander retina.
Topics: Animals; Calcium; Dopamine Antagonists; Dose-Response Relationship, Radiation; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Kinetics; Light; Membrane Potentials; Models, Biological; Neural Conduction; Neurons; Patch-Clamp Techniques; Retina; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Spiperone; Synapses; Time Factors; Urodela | 2003 |