Page last updated: 2024-08-16

spiperone and isoxazoles

spiperone has been researched along with isoxazoles in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gommeren, W; Janssen, PA; Janssen, PM; Leysen, JE; Pauwels, PJ; Wynants, J1
Allen, RC; Dunn, RW; Ellis, DB; Gardner, BA; Glamkowski, EJ; Huger, FP; Jones, MC; Schmid, BL; Stache, U; Strupczewski, JT1
AssiƩ, MB; Koek, W; Sleight, AJ1
Cha, MY; Cho, YS; Choi, BC; Choi, KI; Jung, D; Kang, KH; Koh, HY; Kong, JY; Lee, HY; Pae, AN1
Bordeleau, M; Brooks, KM; Corbett, TJ; de Lannoy, I; Hendrix, JA; Kafka, S; Kamboj, RK; Kapples, KJ; Laws-Ricker, L; Lee, DK; Owolabi, J; Palermo, MG; Rizkalla, G; Shimshock, SJ; Shutske, GM; Tomer, JD; Vargas, HM1
Cha, MY; Cho, H; Choi, KI; Jeong, D; Koh, HY; Kong, JY; Lee, SJ; Pae, AN; Park, WK1

Other Studies

6 other study(ies) available for spiperone and isoxazoles

ArticleYear
In vitro and in vivo receptor binding and effects on monoamine turnover in rat brain regions of the novel antipsychotics risperidone and ocaperidone.
    Molecular pharmacology, 1992, Volume: 41, Issue:3

    Topics: Animals; Antipsychotic Agents; Biogenic Monoamines; Brain; Female; Haloperidol; In Vitro Techniques; Isoxazoles; Male; Neurotransmitter Agents; Piperidines; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Risperidone; Spiperone; Tissue Distribution

1992
Synthesis and neuroleptic activity of 3-(1-substituted-4-piperidinyl)-1,2-benzisoxazoles.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:6

    Topics: Animals; Antipsychotic Agents; Corpus Striatum; In Vitro Techniques; Isoxazoles; Male; Mice; Motor Activity; Oxazoles; Piperidines; Spiperone; Structure-Activity Relationship

1985
Biphasic displacement of [3H]YM-09151-2 binding in the rat brain by thioridazine, risperidone and clozapine, but not by other antipsychotics.
    European journal of pharmacology, 1993, Jun-24, Volume: 237, Issue:2-3

    Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Clozapine; Corpus Striatum; Dopamine D2 Receptor Antagonists; In Vitro Techniques; Isoxazoles; Male; Olfactory Pathways; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Risperidone; Spiperone; Thioridazine

1993
Design and synthesis of a piperazinylalkylisoxazole library for subtype selective dopamine receptor ligands.
    Bioorganic & medicinal chemistry letters, 2002, May-20, Volume: 12, Issue:10

    Topics: Animals; Binding Sites; CHO Cells; Cloning, Molecular; Cricetinae; Drug Design; Humans; Isoxazoles; Kinetics; Ligands; Piperazines; Receptors, Dopamine; Recombinant Proteins; Spiperone; Structure-Activity Relationship; Transfection

2002
Synthesis and structure-activity relationship of the isoindolinyl benzisoxazolpiperidines as potent, selective, and orally active human dopamine D4 receptor antagonists.
    Chembiochem : a European journal of chemical biology, 2002, Oct-04, Volume: 3, Issue:10

    Topics: Administration, Oral; Animals; Apomorphine; Benzyl Compounds; Dizocilpine Maleate; Dopamine D2 Receptor Antagonists; Indoles; Infusions, Parenteral; Isoxazoles; Piperidines; Prazosin; Rats; Receptors, Dopamine D4; Serine; Spiperone; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity

2002
KKHA-761, a potent D3 receptor antagonist with high 5-HT1A receptor affinity, exhibits antipsychotic properties in animal models of schizophrenia.
    Pharmacology, biochemistry, and behavior, 2005, Volume: 82, Issue:2

    Topics: Animals; Antipsychotic Agents; Body Temperature; Catalepsy; Cell Line; Dopamine Uptake Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ion Channels; Isoxazoles; Male; Mice; Mice, Inbred ICR; Piperazines; Postural Balance; Prolactin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D1; Receptors, Dopamine D3; Receptors, Dopamine D4; Reflex, Startle; Schizophrenia; Schizophrenic Psychology; Serotonin Receptor Agonists; Spiperone; Swimming

2005