Page last updated: 2024-08-16

spiperone and ipsapirone

spiperone has been researched along with ipsapirone in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's6 (54.55)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glennon, RA1
Chaput, C; Millan, MJ; Newman-Tancredi, A; Verrièle, L1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L1
Cleves, AE; Jain, AN; Kirshner, D; Langham, JJ; Spitzer, R1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Haj-Dahmane, S; Hamon, M; Lanfumey, L1
Darrow, EJ; Strahlendorf, HK; Strahlendorf, JC1
Colpaert, FC; Millan, MJ1
Davidoff, RA; Hackman, JC; Holohean, AM1
Anwyl, R; Rowan, MJ1
Davidson, C; Hopwood, SE; McLaughlin, DP; Stamford, JA1

Reviews

2 review(s) available for spiperone and ipsapirone

ArticleYear
Central serotonin receptors as targets for drug research.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:1

    Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin

1987
Control of dorsal raphé 5-HT function by multiple 5-HT(1) autoreceptors: parallel purposes or pointless plurality?
    Trends in neurosciences, 2000, Volume: 23, Issue:10

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Second-Generation; Autoreceptors; Dimerization; Guinea Pigs; Humans; Ion Channels; Ion Transport; Mice; Nerve Tissue Proteins; Neurons; Oxadiazoles; Piperazines; Protein Isoforms; Pyridines; Pyrimidines; Raphe Nuclei; Rats; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Second Messenger Systems; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Spiperone; Sumatriptan

2000

Other Studies

9 other study(ies) available for spiperone and ipsapirone

ArticleYear
Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Affinity Labels; Animals; Binding, Competitive; CHO Cells; Cricetinae; Guanine Nucleotides; Hippocampus; Humans; Male; Membranes; Piperazines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists

1998
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
    European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3

    Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes

1998
Physical binding pocket induction for affinity prediction.
    Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19

    Topics: Binding Sites; Ligands; Models, Molecular; Neural Networks, Computer; Peptide Fragments; Protein Binding; Receptor, Serotonin, 5-HT1A

2009
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
K+ channel and 5-hydroxytryptamine1A autoreceptor interactions in the rat dorsal raphe nucleus: an in vitro electrophysiological study.
    Neuroscience, 1991, Volume: 41, Issue:2-3

    Topics: 4-Aminopyridine; Animals; Anti-Anxiety Agents; Apamin; Barium; Charybdotoxin; Electrophysiology; Evoked Potentials; Male; Neurons; Phenylephrine; Potassium Channels; Propranolol; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Scorpion Venoms; Spiperone

1991
Response of cerebellar Purkinje cells to serotonin and the 5-HT1A agonists 8-OH-DPAT and ipsapirone in vitro.
    European journal of pharmacology, 1990, Jan-10, Volume: 175, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Cerebellum; Iontophoresis; Male; Naphthalenes; Purkinje Cells; Pyrimidines; Rats; Rats, Inbred Strains; Serotonin; Spiperone; Tetrahydronaphthalenes

1990
Attenuation of opioid induced antinociception by 5-HT1A partial agonists in the rat.
    Neuropharmacology, 1990, Volume: 29, Issue:3

    Topics: Alprenolol; Analgesics; Animals; Buspirone; Fentanyl; Male; Morphine; Narcotics; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Serotonin; Spiperone; Sufentanil

1990
Changes in membrane potential of frog motoneurons induced by activation of serotonin receptor subtypes.
    Neuroscience, 1990, Volume: 34, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Membrane Potentials; Motor Neurons; Pyrimidines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Spiperone; Tetrahydronaphthalenes

1990
Neurophysiological effects of buspirone and isapirone in the hippocampus: comparison with 5-hydroxytryptamine.
    European journal of pharmacology, 1986, Dec-02, Volume: 132, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Buspirone; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Pyrimidines; Rats; Rats, Inbred Strains; Serotonin; Spiperone

1986