spiperone has been researched along with homovanillic acid in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 47 (77.05) | 18.7374 |
| 1990's | 12 (19.67) | 18.2507 |
| 2000's | 1 (1.64) | 29.6817 |
| 2010's | 1 (1.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Janssen, PF; Laduron, PM; Leysen, JE | 1 |
| Laduron, PM; Leysen, JE | 1 |
| Clow, A; Jenner, P; Marsden, CD; Theodorou, A | 3 |
| Jenner, P; Marsden, CD; Rose, S; Thomas, KL | 1 |
| Farfel, GM; Kleven, MS; Perry, BD; Seiden, LS; Woolverton, WL | 1 |
| Borrelli, E; Haby, C; Hindelang, C; Lisovoski, F; Revel, MO; Schleef, C; Zwiller, J | 1 |
| Wilcox, RE; Young, KA | 1 |
| Greenshaw, AJ; Juorio, AV; Paterson, IA; Zhu, MY | 1 |
| Ben-Shachar, D; Pinhassi, B; Youdim, MB | 1 |
| Mjörndal, T; Persson, SA | 1 |
| Bédard, PJ; Di Paolo, T; Rouillard, C | 1 |
| Burki, HR | 1 |
| Ambrosio, S; Ballarin, M; Blesa, R; Camps, M; Mahy, N; Reiriz, J | 1 |
| Fuller, RW; Hemrick-Luecke, SK; Perry, KW; Toomey, RE | 1 |
| Cross, AJ; Crow, TJ; Ferrier, IN; Johnson, JA; Johnstone, EC; Owen, F; Owens, DG; Poulter, M | 1 |
| Cassel, G; Persson, SA; Sellström, A | 1 |
| Hong, M; Jenner, P; Kilpatrick, GJ; Marsden, CD | 1 |
| Chivers, JK; Jenner, P; Marsden, CD; Reavill, C | 1 |
| Fowler, CJ; Köhler, C; Magnusson, O; Ogren, SO | 1 |
| Cartee, GD; Farrar, RP; MacRae, PG; Spirduso, WW; Wilcox, RE | 1 |
| Bédard, PJ; Di Paolo, T; Falardeau, P | 1 |
| Duyckaerts, C; Gray, F; Hauw, JJ; Hirsch, E; Javoy-Agid, F; LHeureux, R; Morel-Maroger, A; Rascol, A; Ruberg, M; Scatton, B | 1 |
| Fujiwara, Y; Harada, T; Kashihara, K; Ogawa, T; Otsuki, S; Sato, M | 1 |
| Campbell, W; Clark, MS; Mitchell, PJ; Needham, PL; Semple, JM | 1 |
| Fuller, RW; Hemrick-Luecke, SK | 1 |
| Joyce, JN; Loeschen, SK; Marshall, JF | 1 |
| Belfroid, RD; Heerkens, CB; Van der Krogt, JA; Van Valkenburg, CF | 1 |
| Bédard, PJ; Bouchard, S; Boucher, R; Di Paolo, T; Falardeau, P | 1 |
| Barchas, JD; Bowersox, SS; Ciaranello, RD; Dement, WC; Faull, KF; Heller, HC; Kilduff, TS; Radeke, CM; Zeller-DeAmicis, L | 1 |
| Kohjimoto, Y; Kuwaki, T; Nomura, Y; Ono, T; Satoh, H; Shibayama, F; Shirakawa, K | 1 |
| Salama, AI; Saller, CF | 1 |
| Segawa, T; Toide, K; Unemi, N | 1 |
| Aizenstein, ML; Bernardi, MM; De Lucia, R; Scavone, C | 1 |
| Dell, HD; Schöllnhammer, G; Seidel, PR | 1 |
| Horn, AS; Kim, SH; Martin, AR; Yamamura, HI | 1 |
| Waldmeier, PC | 1 |
| Banns, H; Fry, JP; Mann, SP; Sharman, DF; Stephens, DB | 1 |
| Bischoff, S; Ortmann, R; Waldmeier, PC | 1 |
| Baker, HF; Cross, AJ; Crow, TJ; Owen, F; Ridley, RM | 2 |
| Eichenberger, E | 1 |
| Bacopoulos, NG; Brown, SJ; Friedman, MJ; Harris, PQ | 1 |
| Korpi, ER; Wyatt, RJ | 1 |
| Cohen, G; Dembiec-Cohen, D; Hwang, E; Mytilineou, C; Van Woert, M | 1 |
| Himmel, CD; Trulson, ME | 1 |
| Breese, GR; Kilts, CD; Knight, DL; Mailman, RB; Widerlöv, E | 1 |
| Benson, DI; Kuhn, CM; Meyerson, LR; Stanley, M; Virgilio, J; Wazer, D | 1 |
| Jenner, P; Marsden, CD; Murugaiah, K; Theodorou, A | 1 |
| Fuller, RW; Hemrick-Luecke, SK; Snoddy, HD | 1 |
| Agid, Y; Bokobza, B; Javoy-Agid, F; Ruberg, M; Scatton, B | 1 |
| Achilli, G; Algeri, S; Cimino, M; Perego, C; Ponzio, F; Vantini, G | 1 |
| Bacopoulos, NG | 1 |
| Marttila, RJ; Päivärinta, MA; Rinne, JO; Rinne, UK | 1 |
| Ahtee, L; Airio, J; Attila, M; Leikola-Pelho, T | 1 |
| Aizenstein, ML; DeLucia, R; Oliveira, GH; Planeta, CS | 1 |
| Asanuma, M; Hirata, H; Mori, A; Ogawa, N; Ota, Z | 1 |
| Banaschewski, T; Bock, N; Huether, G; Moll, GH; Pilz, J; Rothenberger, A; Rüther, E; Wicker, M | 1 |
| Butler, IJ; Clement-Cormier, YC; Seifert, WE; Wilner, KD | 1 |
| Akaike, A; Izumi, Y; Kume, T; Matsuo, T; Sawada, H; Takada-Takatori, Y; Wakita, S | 1 |
61 other study(ies) available for spiperone and homovanillic acid
| Article | Year |
|---|---|
Spiperone: a ligand of choice for neuroleptic receptors. 2. Regional distribution and in vivo displacement of neuroleptic drugs.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Brain; Butyrophenones; Homovanillic Acid; In Vitro Techniques; Ligands; Male; Rats; Receptors, Drug; Spiperone | 1978 |
Domperidone, a specific in vitro dopamine antagonist, devoid of in vivo central dopaminergic activity.
Topics: Adenylyl Cyclases; Animals; Benzimidazoles; Binding Sites; Cerebral Cortex; Corpus Striatum; Dopamine; Dopamine Antagonists; Haloperidol; Homovanillic Acid; In Vitro Techniques; Piperidines; Rats; Spiperone; Tissue Distribution | 1979 |
Striatal dopamine receptors become supersensitive while rats are geven trifluoperazine for six months.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Apomorphine; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Male; Rats; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Time Factors; Trifluoperazine | 1979 |
Dissociation of the striatal D-2 dopamine receptor from adenylyl cyclase following 6-hydroxydopamine-induced denervation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Benzazepines; Corpus Striatum; Cyclic AMP; Denervation; Dopamine; Ergolines; Female; Homovanillic Acid; Oxidopamine; Prosencephalon; Quinpirole; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone | 1992 |
Effects of repeated injections of cocaine on catecholamine receptor binding sites, dopamine transporter binding sites and behavior in rhesus monkey.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Benzazepines; Brain; Carrier Proteins; Caudate Nucleus; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Administration Schedule; Grooming; Homovanillic Acid; Hydroxyindoleacetic Acid; Iodocyanopindolol; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Organ Specificity; Pindolol; Piperazines; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Serotonin; Spiperone; Stereotyped Behavior; Time Factors | 1992 |
Induction of D2 dopamine receptor mRNA synthesis in a 6-hydroxydopamine parkinsonian rat model.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Blotting, Northern; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Neurons, Efferent; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; RNA, Messenger; Spiperone; Stereotyped Behavior; Substantia Nigra | 1992 |
Characterization of D2 receptors and dopamine levels in the thalamus of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Homovanillic Acid; Ketanserin; Kinetics; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Spiperone; Synaptic Transmission; Thalamus | 1991 |
The effects of some neuroleptics and d-amphetamine on striatal 2-phenylethylamine in the mouse.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dopamine; Fluphenazine; Homovanillic Acid; In Vitro Techniques; Male; Mice; Monoamine Oxidase Inhibitors; Pargyline; Phenethylamines; Selegiline; Spiperone; Synaptic Transmission | 1991 |
Prevention of neuroleptic-induced dopamine D2 receptor supersensitivity by chronic iron salt treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Apomorphine; Brain Chemistry; Chlorpromazine; Chromatography, High Pressure Liquid; Dopamine; Ferrous Compounds; Free Radicals; Hemoglobins; Homovanillic Acid; In Vitro Techniques; Iron; Liver; Male; Nerve Degeneration; Prolactin; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone | 1991 |
Time-related changes in serum perphenazine, striatal 3H-spiperone binding and regional brain acid metabolites of dopamine and 5-hydroxy-tryptamine after a single dose of perphenazine.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Perphenazine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereoisomerism | 1990 |
Effects of chronic treatment of MPTP monkeys with bromocriptine alone or in combination with SKF 38393.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Brain; Brain Chemistry; Bromocriptine; Dopamine; Female; Homovanillic Acid; Kinetics; Levodopa; Macaca fascicularis; Motor Activity; MPTP Poisoning; Parkinson Disease, Secondary; Receptors, Dopamine; Spiperone | 1990 |
Binding of psychoactive drugs to rat brain amine receptors, measured ex vivo, and their effects on the metabolism of biogenic amines.
Topics: Animals; Biogenic Amines; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Methoxyhydroxyphenylglycol; Prazosin; Psychotropic Drugs; Rats; Rats, Inbred Strains; Receptors, Drug; Spiperone | 1986 |
Dopamine D1 and D2 receptors visualized in MPTP treated C57 mice by in vitro autoradiography: lack of evidence of receptor modifications in parkinsonian mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Benzazepines; Brain; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Parkinson Disease, Secondary; Receptors, Dopamine; Spiperone | 1989 |
Pergolide elevation of MHPG sulphate concentration in rat hypothalamus blocked by spiperone and mimicked by other dopamine agonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Butyrophenones; Dopamine; Ergolines; Glycols; Homovanillic Acid; Hypothalamus; Male; Methoxyhydroxyphenylglycol; Pergolide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone | 1985 |
Chemical and structural changes in the brain in patients with movement disorder.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Antipsychotic Agents; Brain; Choline O-Acetyltransferase; Dopamine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Movement Disorders; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Schizophrenia; Spiperone | 1985 |
Acute cyanide intoxication and central transmitter systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Apomorphine; Brain; Cyanides; Cyclic GMP; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Levodopa; Male; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Inbred Strains; Spiperone | 1985 |
Effects of continuous administration for 12 months of amine-depleting drugs and chlorpromazine on striatal dopamine function in the rat.
Topics: Animals; Apomorphine; Body Weight; Chlorpromazine; Corpus Striatum; Dopamine; Homovanillic Acid; Indoles; Kinetics; Male; Motor Activity; Piperazines; Rats; Rats, Inbred Strains; Reserpine; Spiperone; Stereotyped Behavior; Thioxanthenes | 1987 |
Definition of the in-vivo accumulation of [3H]spiperone in brain using haloperidol and sulpiride to determine functional dopamine receptor occupation.
Topics: Animals; Apomorphine; Brain Chemistry; Corpus Striatum; Female; Haloperidol; Homovanillic Acid; Limbic System; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Sulpiride | 1988 |
Dopamine D2 receptors and dopamine metabolism. Relationship between biochemical and behavioural effects of substituted benzamide drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Benzamides; Brain Chemistry; Dopamine; Homovanillic Acid; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Stereotyped Behavior | 1986 |
Endurance training effects on striatal D2 dopamine receptor binding and striatal dopamine metabolite levels.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Homovanillic Acid; Kinetics; Male; Phenylacetates; Physical Exertion; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone | 1987 |
Relation between brain dopamine loss and D2 dopamine receptor density in MPTP monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Kinetics; Macaca fascicularis; Nucleus Accumbens; Ovariectomy; Pyridines; Receptors, Dopamine; Receptors, Dopamine D2; Septal Nuclei; Spiperone | 1988 |
Dopaminergic and cholinergic lesions in progressive supranuclear palsy.
Topics: Aged; Brain; Bulbar Palsy, Progressive; Choline O-Acetyltransferase; Corpus Striatum; Dopamine; Female; Frontal Lobe; Glutamate Decarboxylase; Homovanillic Acid; Humans; Male; Nerve Degeneration; Parkinson Disease, Secondary; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Dopamine; Spiperone; Substantia Innominata; Synaptic Transmission | 1985 |
Effects of intermittent and continuous haloperidol administration on the dopaminergic system in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Drug Administration Schedule; Haloperidol; Homovanillic Acid; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Synaptic Transmission | 1986 |
BRL 20596, a novel anilide with central dopamine antagonist activity.
Topics: Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Brain Chemistry; Catalepsy; Dextroamphetamine; Dopamine Antagonists; Drug Synergism; Electroencephalography; Hemodynamics; Hexobarbital; Homovanillic Acid; Isonipecotic Acids; Male; Mice; Motor Activity; Prolactin; Rats; Rats, Inbred Strains; Spiperone; Stereotyped Behavior | 1986 |
Decrease in hypothalamic epinephrine concentration and other neurochemical changes produced by quinpirole, a dopamine agonist, in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Epinephrine; Ergolines; Homovanillic Acid; Hypothalamus; Male; Norepinephrine; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone | 1985 |
Dopamine D-2 receptors in rat caudate-putamen: the lateral to medial gradient does not correspond to dopaminergic innervation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Caudate Nucleus; Dopamine; Homovanillic Acid; Male; Putamen; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone | 1985 |
Repeated administration of HA-966 and haloperidol to rats: similar tolerance to striatal dopamine accumulation after HA-966 challenge, but dissimilar effects on striatal [3H]spiperone binding.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Drug Tolerance; Haloperidol; Homovanillic Acid; Male; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone | 1988 |
Behavioral and biochemical effect of chronic treatment with D-1 and/or D-2 dopamine agonists in MPTP monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Benzazepines; Brain Chemistry; Dopamine; Dyskinesia, Drug-Induced; Female; Homovanillic Acid; Macaca fascicularis; Motor Activity; Parkinson Disease, Secondary; Pyridines; Receptors, Dopamine; Spiperone | 1988 |
Modulation of activity of the striatal dopaminergic system during the hibernation cycle.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Hibernation; Homovanillic Acid; Kinetics; Receptors, Dopamine; Sciuridae; Spiperone | 1987 |
Effect of long-term dosing with tiapride on brain dopamine receptors and metabolism in rats. Comparative study with sulpiride and haloperidol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Apomorphine; Benzamides; Brain Chemistry; Dopamine; Haloperidol; Homovanillic Acid; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Sulpiride; Tiapamil Hydrochloride | 1987 |
Dopamine receptor subtypes: in vivo biochemical evidence for functional interaction.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Benzazepines; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone | 1985 |
Effects of a fluorinated pyrimidinedione anti-cancer drug, 5-fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione (FT), and related compounds on nigro-striatal dopaminergic neurons in the central nervous system.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Antineoplastic Agents; Corpus Striatum; Dopamine; Fluorouracil; Haloperidol; Homovanillic Acid; Male; Methyltyrosines; Motor Activity; Neurons; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Substantia Nigra; Tegafur; Time Factors; Uracil | 1985 |
Striatal dopamine receptor sensitivity after subchronic fencamfamine in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Corpus Striatum; Homovanillic Acid; Humans; In Vitro Techniques; Kinetics; Male; Motor Activity; Norbornanes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior | 1985 |
[Biochemical studies on tienocarbine and related compounds].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Binding, Competitive; Brain Chemistry; Catecholamines; Caudate Nucleus; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Indoles; Male; Norepinephrine; Putamen; Rats; Rats, Inbred Strains; Serotonin; Spiperone; Structure-Activity Relationship; Thiophenes | 1984 |
Changes in rat striatal dopamine turnover and receptor activity during one years neuroleptic administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Binding Sites; Corpus Striatum; Cyclic AMP; Dopamine; Homovanillic Acid; Male; Rats; Receptors, Dopamine; Spiperone; Thioridazine; Time Factors; Trifluoperazine | 1980 |
Cerebral dopamine function in rats following withdrawal from one year of continuous neuroleptic administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Binding Sites; Body Weight; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Male; Motor Activity; Mouth; Movement; Rats; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Substance Withdrawal Syndrome; Thioridazine; Time Factors; Trifluoperazine | 1980 |
Conformationally restricted phenothiazine neuroleptics. 1. 3-(Dimethylamino)-1,2,3,4-tetrahydroazepino[3,2,1-kl]phenothiazine.
Topics: Animals; Antipsychotic Agents; Cattle; Caudate Nucleus; Corpus Striatum; Homovanillic Acid; In Vitro Techniques; Male; Models, Molecular; Molecular Conformation; Phenothiazines; Rats; Receptors, Dopamine; Spiperone; Structure-Activity Relationship | 1980 |
Effects of antidepressant drugs on dopamine uptake and metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Brain; Dopamine; Homovanillic Acid; Methyltyrosines; Rats; Spiperone | 1982 |
Cerebral dopamine metabolism and stereotyped behaviour in early-weaned piglets.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain; Brain Chemistry; Caudate Nucleus; Dopamine; Homovanillic Acid; Spiperone; Swine; Time Factors; Tyrosine 3-Monooxygenase; Weaning | 1982 |
Modulation of dopaminergic transmission by alpha-noradrenergic agonists and antagonists: evidence for antidopaminergic properties of some alpha antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Dopamine; Female; Haloperidol; Homovanillic Acid; Male; Prazosin; Rats; Spiperone; Synaptic Transmission; Yohimbine | 1982 |
Effect of chronic amphetamine administration on dopaminergic systems in the vervet brain: relationship to findings in the brains of schizophrenics.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Brain; Chlorocebus aethiops; Dopa Decarboxylase; Dopamine; Homovanillic Acid; Humans; Schizophrenia; Spiperone; Tyrosine 3-Monooxygenase | 1983 |
Pharmacology of fluperlapine compared with clozapine.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Apomorphine; Binding, Competitive; Brain Chemistry; Clozapine; Dibenzazepines; Dopamine; Electroencephalography; Homovanillic Acid; Humans; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior | 1984 |
Plasma drug and homovanillic acid levels in psychotic patients receiving neuroleptics.
Topics: Animals; Antipsychotic Agents; Cattle; Caudate Nucleus; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Homovanillic Acid; Humans; Phenylacetates; Psychotic Disorders; Radioligand Assay; Receptors, Dopamine; Spiperone | 1984 |
Reduced haloperidol: effects on striatal dopamine metabolism and conversion to haloperidol in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Binding, Competitive; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Liver; Male; Membranes; Rats; Rats, Inbred Strains; Serotonin; Spiperone | 1984 |
Explant cultures of dog substantia nigra and striatum: a model for the study of nigro-striatal dopamine neurons.
Topics: Animals; Autoradiography; Cell Differentiation; Corpus Striatum; Culture Techniques; Dogs; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Microscopy, Fluorescence; Neural Pathways; Neurons; Receptors, Dopamine; Spiperone; Substantia Nigra; Synaptic Transmission | 1983 |
Decreased brain dopamine synthesis rate and increased [3H]spiroperidol binding in streptozotocin-diabetic rats.
Topics: Animals; Brain; Butyrophenones; Diabetes Mellitus, Experimental; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Insulin; Kinetics; Probenecid; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone | 1983 |
Effects of thioridazine and its metabolites on dopaminergic function: drug metabolism as a determinant of the antidopaminergic actions of thioridazine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Dextroamphetamine; Dopamine; Homovanillic Acid; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Thioridazine | 1984 |
Lack of potency of metoclopramide's metabolites in various dopaminergic models.
Topics: Animals; Apomorphine; Dopamine; Fluphenazine; Haloperidol; Homovanillic Acid; Humans; Male; Metoclopramide; Prolactin; Rats; Rats, Inbred Strains; Spiperone; Stereotyped Behavior; Tetrahydronaphthalenes | 1983 |
Alterations in cerebral dopamine function caused by administration of cis- or trans-flupenthixol for up to 18 months.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Corpus Striatum; Dopamine; Flupenthixol; Homovanillic Acid; Humans; Limbic System; Male; Rats; Rats, Inbred Strains; Spiperone; Stereotyped Behavior; Thioxanthenes; Time Factors | 1983 |
Increase in serum corticosterone concentration and decrease in hypothalamic epinephrine concentration by N-propylnorapomorphine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Corticosterone; Epinephrine; Homovanillic Acid; Hypothalamus; Male; Rats; Rats, Inbred Strains; Spiperone | 1984 |
[3H]spiperone binding, dopamine and HVA concentrations in Parkinson's disease and supranuclear palsy.
Topics: Aged; Brain; Butyrophenones; Caudate Nucleus; Dopamine; Homovanillic Acid; Humans; Levodopa; Nucleus Accumbens; Paralysis; Parkinson Disease; Phenylacetates; Putamen; Receptors, Dopamine; Spiperone; Substantia Nigra | 1984 |
Effect of chronic amphetamine administration on central dopaminergic mechanisms in the vervet.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Chlorocebus aethiops; Dextroamphetamine; Dopamine; Female; Homovanillic Acid; Kinetics; Male; Membranes; Receptors, Dopamine; Spiperone | 1981 |
Study on some compensatory responses of dopaminergic system in aging rats.
Topics: Aging; Animals; Apomorphine; Butyrophenones; Corpus Striatum; Feedback; Haloperidol; Homovanillic Acid; Male; Rats; Receptors, Dopamine; Spiperone | 1982 |
Biochemical mechanism of tolerance to neuroleptic drugs; regional differences in rat brain.
Topics: Animals; Butyrophenones; Caudate Nucleus; Cerebral Cortex; Dopamine; Drug Tolerance; Fluphenazine; Haloperidol; Homovanillic Acid; Rats; Spiperone | 1981 |
Dopaminergic neurotransmission in chronic herpes simplex virus brain infection in rabbits.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Encephalitis; Female; Herpes Simplex; Herpesvirus 1, Human; Homovanillic Acid; Hydroxyindoleacetic Acid; Mesencephalon; Motor Activity; Norepinephrine; Organ Specificity; Posture; Rabbits; Receptors, Dopamine D2; Rotation; Serotonin; Spiperone; Synaptic Transmission | 1993 |
Withdrawal from repeated morphine sensitizes mice to the striatal dopamine release enhancing effect of acute morphine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzazepines; Dopamine; Homovanillic Acid; In Vitro Techniques; Male; Methyltyrosines; Mice; Morphine; Receptors, Dopamine; Spiperone; Visual Cortex | 1994 |
Daily variation in plasma concentration of fencamfamine and striatal dopamine receptors in rats.
Topics: Animals; Chromatography, Gas; Circadian Rhythm; Corpus Striatum; Homovanillic Acid; Injections, Intraperitoneal; Male; Norbornanes; Rats; Rats, Wistar; Receptors, Dopamine; Spiperone; Time Factors | 1994 |
Effect of chronic ceruletide treatment on dopaminergic neurotransmitters, receptors and their mRNAs in the striatum of rats with dyskinesia induced by iminodipropionitrile.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzazepines; Blotting, Northern; Ceruletide; Corpus Striatum; Dopamine; Drug Administration Schedule; Dyskinesia, Drug-Induced; Homovanillic Acid; Male; Neurotoxins; Nitriles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Spiperone; Time Factors | 1993 |
Early administration of tiapride to young rats without long-lasting changes in the development of the dopaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Binding Sites; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Homovanillic Acid; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Receptors, Dopamine D2; Spiperone; Tiapamil Hydrochloride; Time Factors | 2004 |
Biochemical alterations of dopamine receptor responses following chronic L-dopa therapy.
Topics: Adenylyl Cyclases; Animals; Carbidopa; Corpus Striatum; Dopamine; Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Spiperone | 1980 |
Haloperidol, spiperone, pimozide and aripiprazole reduce intracellular dopamine content in PC12 cells and rat mesencephalic cultures: Implication of inhibition of vesicular transport.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Aripiprazole; Ascorbic Acid; Biological Transport; Dopamine; Extracellular Space; Gene Expression Regulation, Enzymologic; Haloperidol; Homovanillic Acid; Mesencephalon; Neurons; Pargyline; PC12 Cells; Pimozide; Piperazines; Quinolones; Rats; Spiperone; Transport Vesicles; Tyrosine 3-Monooxygenase | 2010 |