Page last updated: 2024-08-16

spiperone and flupenthixol

spiperone has been researched along with flupenthixol in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199029 (78.38)18.7374
1990's6 (16.22)18.2507
2000's1 (2.70)29.6817
2010's1 (2.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Höllt, V; Schubert, P1
Crooke, ST; Flaim, KE; Gessner, GW; Sarau, HM; Weinstock, J1
Hösli, E; Hösli, L1
Kilbourn, MR1
Rinne, JO1
Arnt, J1
Jenner, P; Kilpatrick, GJ; Marsden, CD2
Huff, RM; Molinoff, PB1
Creese, I; Leff, SE1
Israel, JM; Jaquet, P; Vincent, JD1
Christensen, AV; Hyttel, J1
Fleminger, S; Hall, MD; Jenner, P; Marsden, CD; Rupniak, NM1
Cross, AJ; Ross, ST; Waddington, JL1
Agnati, LF; Andersson, K; Benfenati, F; Camurri, M; Fuxe, K; Zoli, M1
Huff, RM; McGonigle, P; Molinoff, PB1
Lee, EK; Tamminga, CA; Walters, JR; Waszczak, BL1
Coppings, RJ; Giachetti, A; Krulich, L; Mayfield, MA; McCann, SM1
Bruinink, A; Davis, MD; Lichtensteiger, W; Schlumpf, M1
Fleminger, S; Hall, MD; Jenner, P; Marsden, CD; Murugaiah, K; Theodorou, A1
Fleminger, S; Jenner, P; Marsden, CD; Murugaiah, K; Theodorou, A1
Jenner, P; Marsden, CD; Murugaiah, K; Theodorou, A1
Chen, A; Creese, I; Leff, SE1
Crow, TJ; Mashal, RD; Owen, F; Poulter, M; Veall, N; Zanelli, GD1
Cross, AJ; Crow, TJ; Johnstone, EC; Owen, F; Owens, DG; Waddington, JL1
Adams, L; Creese, I; Hyttel, J; Leff, S1
Cross, AJ; Waddington, JL1
Cross, AJ; Owen, F1
Chuang, YC; Huang, WT; Lin, MT; Liu, HS; Won, SJ1
Panajotova, V1
Fox, K; Lam, P; Ling, V; Shapiro, AB1
Chagkutip, J; Govitrapong, P; Srikiatkhachorn, A; Turakitwanakan, W1
Beggs, KT; Mercer, AR; Tyndall, JD1
George, SR; Guan, HC; Laurier, LG; Ng, G; Niznik, HB; O'Dowd, BF; Seeman, P; Sunahara, RK; Torchia, J; Van Tol, HH1
Andrews, PR; Craik, DJ; Martin, JL1
Baldessarini, RJ; Booth, RG; Charifson, PS; Kula, NS; McPhail, AT; Myers, AM; Owens, CE; Wyrick, SD1
Booth, RG; Brown, RL; Bucholtz, EC; Tropsha, A; Wyrick, SD1

Reviews

1 review(s) available for spiperone and flupenthixol

ArticleYear
A comprehensive method for the quantitative determination of dopamine receptor subtypes.
    Annals of the New York Academy of Sciences, 1984, Volume: 430

    Topics: Animals; Binding, Competitive; Corpus Striatum; Dopamine; Dopamine Antagonists; Flupenthixol; GTP-Binding Proteins; Guanosine Triphosphate; Mathematics; Radioligand Assay; Receptors, Cell Surface; Receptors, Dopamine; Receptors, Serotonin; Spiperone; Tritium

1984

Other Studies

36 other study(ies) available for spiperone and flupenthixol

ArticleYear
Demonstration of neuroleptic receptor sites in mouse brain by autoradiography.
    Brain research, 1978, Jul-28, Volume: 151, Issue:1

    Topics: Animals; Autoradiography; Binding Sites; Brain; Butyrophenones; Cerebellum; Corpus Striatum; Flupenthixol; Hippocampus; Male; Median Eminence; Mice; Receptors, Drug; Spiperone; Synapses; Thioxanthenes

1978
Binding of a novel dopaminergic agonist radioligand [3H]-fenoldopam (SKF 82526) to D-1 receptors in rat striatum.
    Life sciences, 1985, Apr-15, Volume: 36, Issue:15

    Topics: Adenylyl Cyclase Inhibitors; Animals; Benzazepines; Binding, Competitive; Caudate Nucleus; Fenoldopam; Flupenthixol; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Putamen; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Sodium; Spiperone

1985
Binding sites for [3H]dopamine and dopamine-antagonists on cultured astrocytes of rat striatum and spinal cord: an autoradiographic study.
    Neuroscience letters, 1986, Apr-11, Volume: 65, Issue:2

    Topics: Animals; Astrocytes; Autoradiography; Binding Sites; Cells, Cultured; Corpus Striatum; Domperidone; Dopamine; Dopamine Antagonists; Flupenthixol; Ketanserin; Piperidines; Rats; Spinal Cord; Spiperone; Stereoisomerism; Tritium

1986
In vivo binding of [18F]GBR 13119 to the brain dopamine uptake system.
    Life sciences, 1988, Volume: 42, Issue:14

    Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Dopamine; Flupenthixol; Kinetics; Mazindol; Nomifensine; Piperazines; Rats; Rats, Inbred Strains; Spiperone

1988
Muscarinic and dopaminergic receptors in the aging human brain.
    Brain research, 1987, Feb-24, Volume: 404, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Brain; Child; Child, Preschool; Flupenthixol; Humans; Middle Aged; Prostaglandins; Quinuclidinyl Benzilate; Receptors, Dopamine; Receptors, Muscarinic; Regression Analysis; Spiperone; Thromboxanes

1987
Hyperactivity induced by stimulation of separate dopamine D-1 and D-2 receptors in rats with bilateral 6-OHDA lesions.
    Life sciences, 1985, Aug-26, Volume: 37, Issue:8

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzamides; Benzazepines; Clopenthixol; Dopamine; Dose-Response Relationship, Drug; Ergolines; Flupenthixol; Hydroxydopamines; Hypothalamus; Male; Motor Activity; Oxidopamine; Pergolide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone

1985
Specific [3H]piflutixol binding to CHAPS-solubilised rat striatal preparations involves dopamine D-2 but not D-1 binding sites.
    Journal of neurochemistry, 1986, Volume: 46, Issue:2

    Topics: Animals; Binding Sites; Binding, Competitive; Cholic Acids; Chromatography, Gel; Corpus Striatum; Flupenthixol; Isomerism; Kinetics; Rats; Receptors, Dopamine; Solubility; Spiperone; Sulpiride; Thioxanthenes

1986
Assay of dopamine receptors with [alpha-3H]flupenthixol.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:1

    Topics: Animals; Binding, Competitive; Flupenthixol; Guanosine Triphosphate; Kinetics; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Thioxanthenes

1985
Interactions of dopaminergic agonists and antagonists with dopaminergic D3 binding sites in rat striatum. Evidence that [3H]dopamine can label a high affinity agonist-binding state of the D1 dopamine receptor.
    Molecular pharmacology, 1985, Volume: 27, Issue:2

    Topics: Animals; Apomorphine; Binding Sites; Binding, Competitive; Corpus Striatum; Dopamine; Ergot Alkaloids; Flupenthixol; Guanine Nucleotides; In Vitro Techniques; Rats; Receptors, Dopamine; Spiperone; Tritium

1985
The electrical properties of isolated human prolactin-secreting adenoma cells and their modification by dopamine.
    Endocrinology, 1985, Volume: 117, Issue:4

    Topics: Adenoma; Bromocriptine; Domperidone; Dopamine; Dose-Response Relationship, Drug; Electrophysiology; Flupenthixol; Haloperidol; Humans; In Vitro Techniques; Membrane Potentials; Phenethylamines; Pituitary Neoplasms; Prolactin; Receptors, Dopamine; Spiperone; Time Factors

1985
The binding of [3H]N-(chloroethyl)-norapomorphine to rat striatal membranes.
    European journal of pharmacology, 1984, Dec-15, Volume: 107, Issue:1

    Topics: Amisulpride; Animals; Aporphines; Binding, Competitive; Butaclamol; Corpus Striatum; Dopamine Antagonists; Female; Flupenthixol; Hydrogen-Ion Concentration; In Vitro Techniques; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereoisomerism; Sulpiride; Tritium

1984
Biochemical and pharmacological differentiation of neuroleptic effect on dopamine D-1 and D-2 receptors.
    Journal of neural transmission. Supplementum, 1983, Volume: 18

    Topics: Animals; Antipsychotic Agents; Binding, Competitive; Flupenthixol; Haloperidol; Rats; Receptors, Dopamine; Spiperone; Thioxanthenes

1983
Changes in apomorphine-induced stereotypy as a result of subacute neuroleptic treatment correlates with increased D-2 receptors, but not with increases in D-1 receptors.
    Biochemical pharmacology, 1983, Oct-01, Volume: 32, Issue:19

    Topics: Animals; Antipsychotic Agents; Apomorphine; Brain; Drug Synergism; Flupenthixol; Haloperidol; Humans; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Stereotyped Behavior; Sulpiride; Thioxanthenes

1983
Irreversible interaction of beta-haloalkylamine derivatives with dopamine D1 and D2 receptors.
    Life sciences, 1983, Jun-13, Volume: 32, Issue:24

    Topics: Animals; Butyrophenones; Cattle; Corpus Striatum; Flupenthixol; Nitrogen Mustard Compounds; Phenothiazines; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Structure-Activity Relationship; Thioxanthenes

1983
Evidence for the existence of a dopamine receptor of the D-1 type in the rat median eminence.
    Neuroscience letters, 1983, Dec-30, Volume: 43, Issue:2-3

    Topics: Animals; Binding, Competitive; Flupenthixol; Male; Median Eminence; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Spiperone

1983
Effect of dopamine system activation on substantia nigra pars reticulata output neurons: variable single-unit responses in normal rats and inhibition in 6-hydroxydopamine-lesioned rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1984, Volume: 4, Issue:9

    Topics: Animals; Apomorphine; Dopamine; Efferent Pathways; Flupenthixol; Haloperidol; Hydroxydopamines; Injections, Intravenous; Male; Neural Inhibition; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Spiperone; Substantia Nigra; Tectum Mesencephali; Thalamus

1984
Lack of evidence that the central serotoninergic system plays a role in the activation of prolactin secretion following inhibition of dopamine synthesis or blockade of dopamine receptors in the male rat.
    Neuroendocrinology, 1980, Volume: 30, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Cyproheptadine; Depression, Chemical; Dopamine; Dopamine Antagonists; Fenclonine; Fluoxetine; Flupenthixol; Hypothalamus; Male; Methysergide; Prolactin; Rats; Receptors, Dopamine; Receptors, Serotonin; Spiperone; Stimulation, Chemical; Tyrosine

1980
Early postnatal development of pituitary intermediate lobe control in the rat by dopamine neurons.
    Neuroendocrinology, 1984, Volume: 39, Issue:1

    Topics: Animals; Catecholamines; Dopamine; Dopamine Antagonists; Female; Flupenthixol; Histocytochemistry; Male; Melanocyte-Stimulating Hormones; Neurons; Norepinephrine; Pituitary Gland; Rats; Rats, Inbred Strains; Spiperone

1984
Alterations in different populations of striatal dopamine receptors produced by 18 months continuous administration of cis- or trans-flupenthixol to rats.
    Neuropharmacology, 1984, Volume: 23, Issue:6

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Body Weight; Catalepsy; Corpus Striatum; Flupenthixol; Humans; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereoisomerism; Stereotyped Behavior; Thioxanthenes

1984
Persistent increase in striatal dopamine stimulated adenylate cyclase activity persists for more than 6 months but disappears after 1 year following withdrawal from 18 months cis-flupenthixol intake.
    Biochemical pharmacology, 1983, Sep-01, Volume: 32, Issue:17

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Binding Sites; Corpus Striatum; Dopamine; Flupenthixol; Humans; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Thioxanthenes; Time Factors

1983
Alterations in cerebral dopamine function caused by administration of cis- or trans-flupenthixol for up to 18 months.
    Neuroscience, 1983, Volume: 10, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Corpus Striatum; Dopamine; Flupenthixol; Homovanillic Acid; Humans; Limbic System; Male; Rats; Rats, Inbred Strains; Spiperone; Stereotyped Behavior; Thioxanthenes; Time Factors

1983
Sulpiride isomers exhibit reversed stereospecificity for D-1 and D-2 dopamine receptors in the CNS.
    Neuropharmacology, 1984, Volume: 23, Issue:5

    Topics: Animals; Brain Chemistry; Corpus Striatum; Flupenthixol; In Vitro Techniques; Rats; Receptors, Dopamine; Spiperone; Stereoisomerism; Sulpiride

1984
77Br-p-bromospiperone: a ligand for in vivo labelling of dopamine receptors.
    Life sciences, 1983, Aug-22, Volume: 33, Issue:8

    Topics: Animals; Brain; Bromine; Butyrophenones; Cerebellum; Corpus Striatum; Flupenthixol; Haloperidol; Male; Radioisotopes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Tissue Distribution

1983
Abnormal involuntary movements in schizophrenia: are they related to the disease process or its treatment? Are they associated with changes in dopamine receptors?
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:5

    Topics: Adult; Aged; Brain; Dyskinesia, Drug-Induced; Female; Flupenthixol; Humans; Male; Middle Aged; Mouth Diseases; Receptors, Dopamine; Schizophrenia; Species Specificity; Spiperone

1982
Kainate lesion dissociates striatal dopamine receptor radioligand binding sites.
    European journal of pharmacology, 1981, Mar-05, Volume: 70, Issue:1

    Topics: Animals; Apomorphine; Benzimidazoles; Corpus Striatum; Domperidone; Flupenthixol; In Vitro Techniques; Kainic Acid; Male; Piperidines; Pyrrolidines; Radioligand Assay; Rats; Receptors, Dopamine; Spiperone

1981
Kainic acid lesions dissociate [3H] spiperone and [3H]cis-flupenthixol binding sites in rat striatum.
    European journal of pharmacology, 1981, May-08, Volume: 71, Issue:2-3

    Topics: Animals; Binding Sites; Butyrophenones; Corpus Striatum; Flupenthixol; Glutamate Decarboxylase; Kainic Acid; Male; Pyrrolidines; Rats; Receptors, Dopamine; Spiperone; Thioxanthenes; Tritium

1981
Characteristics of 3H-cis-flupenthixol binding to calf brain membranes.
    European journal of pharmacology, 1980, Aug-08, Volume: 65, Issue:4

    Topics: Adenylyl Cyclases; Animals; Brain; Butyrophenones; Cattle; Dopamine; Flupenthixol; In Vitro Techniques; Membranes; Spiperone; Thioxanthenes

1980
Suppression of natural killer cell activity in mouse spleen lymphocytes by several dopamine receptor antagonists.
    Experientia, 1995, Apr-15, Volume: 51, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Cytotoxicity, Immunologic; Dopamine Antagonists; Flupenthixol; Fluphenazine; Killer Cells, Natural; Mice; Mice, Inbred C3H; Pimozide; Spiperone; Spleen; Thiothixene; Trifluoperazine

1995
The effect of dopaminergic agents on cell-mediated immune response in mice.
    Physiological research, 1997, Volume: 46, Issue:2

    Topics: Animals; Benzazepines; Binding Sites; Dopamine Agonists; Dopamine Antagonists; Female; Flupenthixol; Graft vs Host Reaction; Immunity, Cellular; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Pergolide; Receptors, Dopamine; Salicylamides; Spiperone; Spleen

1997
Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone. Evidence for a third drug-binding site.
    European journal of biochemistry, 1999, Volume: 259, Issue:3

    Topics: Allosteric Site; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Binding Sites; Biological Transport; Cell Membrane; CHO Cells; Cricetinae; Fluorescent Dyes; Flupenthixol; Haloperidol; Molecular Structure; Prazosin; Progesterone; Propranolol; Protein Binding; Rhodamine 123; Spiperone

1999
Platelet 5-HT(2A) receptors in schizophrenic patients with and without neuroleptic treatment.
    Psychiatry research, 2000, Sep-25, Volume: 96, Issue:1

    Topics: Adult; Antipsychotic Agents; Blood Platelets; Case-Control Studies; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Flupenthixol; Humans; Ketanserin; Male; Phenothiazines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Risperidone; Schizophrenia; Serotonin Antagonists; Spiperone

2000
Honey bee dopamine and octopamine receptors linked to intracellular calcium signaling have a close phylogenetic and pharmacological relationship.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: Amino Acid Sequence; Animals; Bees; Binding Sites; Calcium; Calcium Signaling; Cell Line; Cyclic AMP; Dibenzazepines; Flupenthixol; Humans; Imidazoles; Molecular Sequence Data; Phylogeny; Receptors, Biogenic Amine; Receptors, Dopamine; Sequence Homology, Amino Acid; Signal Transduction; Spiperone

2011
Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.
    Nature, 1991, Apr-18, Volume: 350, Issue:6319

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain; Cell Line; Cell Membrane; Cloning, Molecular; Dopamine; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Oligonucleotide Probes; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D5; RNA, Messenger; Sequence Homology, Nucleic Acid; Transfection

1991
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Conformational analysis, pharmacophore identification, and comparative molecular field analysis of ligands for the neuromodulatory sigma 3 receptor.
    Journal of medicinal chemistry, 1994, Nov-25, Volume: 37, Issue:24

    Topics: Animals; Ligands; Models, Molecular; Molecular Conformation; Receptors, sigma; Rodentia; Structure-Activity Relationship; Tetrahydronaphthalenes

1994
Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes

1999