spiperone has been researched along with desipramine in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (61.54) | 18.7374 |
| 1990's | 8 (30.77) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Booth, RG; Brown, RL; Bucholtz, EC; Tropsha, A; Wyrick, SD | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Clark, D; Willner, P | 1 |
| Klimek, V; Maj, J; Rawlów, A; Sarnek, J | 1 |
| Greenshaw, AJ; Paetsch, PR | 1 |
| Cowburn, R; Lindqvist, E; Luthman, J; Young, D | 1 |
| Inoue, O; Kobayasi, K; Suhara, T | 1 |
| Allin, R; Reyneke, L; Russell, VA; Taljaard, JJ | 1 |
| Klimek, V; Maj, J; Wedzony, K | 1 |
| Burchinsky, SG | 1 |
| Crews, FT; Scott, JA; Shorstein, NH | 1 |
| Agnati, LF; Benfenati, F; Fuxe, K; Ogren, SO | 1 |
| Goodwin, GM; Green, AR; Johnson, P | 1 |
| Coscina, DV; Dumbrille-Ross, A; Tang, SW | 1 |
| Hall, H; Ross, SB; Sällemark, M | 1 |
| Fibiger, HC; Leclere, JF; Martin-Iverson, MT | 1 |
| Kwan, S; Seeman, P; Tang, SW | 1 |
| Lee, T; Tang, SW | 1 |
| Koide, T; Matsushita, H | 1 |
| Couvée, JH; Dijcks, FA; Ruigt, GS | 1 |
| Horikawa, T; Nomura, Y; Okada, F; Tokumitsu, Y | 1 |
| Blier, P; de Montigny, C; Mongeau, R; Weiss, M | 1 |
3 review(s) available for spiperone and desipramine
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
Neurotransmitter receptors in the central nervous system and aging: pharmacological aspect (review).
Topics: Adenylyl Cyclases; Aging; Animals; Brain; Desipramine; Dopamine; Dopamine Antagonists; Female; Fluphenazine; Haloperidol; Humans; Male; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Cholinergic; Receptors, Dopamine; Receptors, GABA-A; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Serotonin; Reserpine; Scopolamine; Spiperone; Tetrahydronaphthalenes; Tissue Distribution; Tritium | 1984 |
Central 5-HT neurons as targets for antidepressant drug action: differential modulation of 5-HT receptor populations in the central nervous system of the rat.
Topics: Animals; Antidepressive Agents; Autoradiography; Avoidance Learning; Binding Sites; Central Nervous System; Desipramine; Histocytochemistry; Imipramine; Immunochemistry; Methoxydimethyltryptamines; Movement; Rats; Receptors, Serotonin; Spiperone; Zimeldine | 1984 |
23 other study(ies) available for spiperone and desipramine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes | 1999 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
A reappraisal of the interaction between tricyclic antidepressants and reserpine-like drugs.
Topics: Animals; Antidepressive Agents, Tricyclic; Conditioning, Operant; Desipramine; Drug Interactions; Male; Motor Activity; Phenoxybenzamine; Phentolamine; Pimozide; Rats; Reserpine; Spiperone; Tetrabenazine; Time Factors | 1978 |
On the anticataleptic action of cyproheptadine.
Topics: Animals; Atropine; Catalepsy; Clomipramine; Cyproheptadine; Desipramine; Female; Fluphenazine; Humans; Imipramine; Male; Methyltyrosines; Pilocarpine; Pimozide; Promethazine; Rats; Reserpine; Spiperone | 1976 |
Effects of chronic antidepressant treatment on dopamine-related [3H]SCH 23390 and [3H]spiperone binding in the rat striatum.
Topics: Animals; Antidepressive Agents; Benzazepines; Corpus Striatum; Desipramine; Kinetics; Male; Phenelzine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Spiperone; Tranylcypromine | 1992 |
Neonatal dopamine lesion in the rat results in enhanced adenylate cyclase activity without altering dopamine receptor binding or dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein (DARPP-32) immunoreactivity.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Basal Ganglia; Benzazepines; Corpus Striatum; Cyclic AMP; Desipramine; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Hydroxydopamines; Male; Nerve Tissue Proteins; Oxidopamine; Phosphoproteins; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Tyrosine 3-Monooxygenase | 1990 |
Effect of desipramine on dopamine receptor binding in vivo.
Topics: Animals; Antidepressive Agents, Tricyclic; Benzazepines; Cerebellum; Corpus Striatum; Desipramine; Dose-Response Relationship, Drug; In Vitro Techniques; Ketanserin; Male; Mice; Receptors, Dopamine; Spiperone | 1990 |
Lack of effect of chronic desipramine treatment on dopaminergic activity in the nucleus accumbens of the rat.
Topics: Acetylcholine; Animals; Benzazepines; Desipramine; Dopamine; Dopamine Agents; Dopamine Antagonists; Electric Stimulation; Ergolines; Male; Nomifensine; Nucleus Accumbens; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Septal Nuclei; Spiperone | 1989 |
Desipramine given repeatedly enhances behavioural effects of dopamine and d-amphetamine injected into the nucleus accumbens.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Binding, Competitive; Brain Chemistry; Desipramine; Dextroamphetamine; Dopamine; Female; Injections; Male; Nucleus Accumbens; Rats; Rats, Inbred Strains; Spiperone | 1987 |
Rapid down-regulation of serotonin2 receptor binding during combined administration of tricyclic antidepressant drugs and alpha 2 antagonists.
Topics: Adrenergic alpha-Antagonists; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cerebral Cortex; Desipramine; Kinetics; Male; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone | 1983 |
5-HT2 receptor characteristics in frontal cortex and 5-HT2 receptor-mediated head-twitch behaviour following antidepressant treatment to mice.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Behavior, Animal; Brain; Cerebral Cortex; Desipramine; Frontal Lobe; Kinetics; Male; Mianserin; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Radioligand Assay; Receptors, Serotonin; Spiperone; Tranylcypromine; Zimeldine | 1984 |
Lack of effect of raphe lesions on serotonin S2 receptor changes induced by amitriptyline and desmethylimipramine.
Topics: Amitriptyline; Animals; Brain Stem; Cerebral Cortex; Corpus Striatum; Desipramine; Dopamine; Hypothalamus; Male; Mesencephalon; Mianserin; Norepinephrine; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Synaptic Transmission | 1982 |
Effect of destruction of central noradrenergic and serotonergic nerve terminals by systemic neurotoxins on the long-term effects of antidepressants on beta-adrenoceptors and 5-HT2 binding sites in the rat cerebral cortex.
Topics: Alanine; Amines; Animals; Antidepressive Agents; Benzylamines; Binding Sites; Cerebral Cortex; Clenbuterol; Desipramine; Dihydroalprenolol; Male; Mianserin; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Spiperone; Zimeldine | 1984 |
Cholinergic-dopaminergic interactions and the mechanisms of action of antidepressants.
Topics: 5,7-Dihydroxytryptamine; Animals; Antidepressive Agents; Brain Chemistry; Corpus Striatum; Desipramine; Dextroamphetamine; Hydroxydopamines; Male; Motor Activity; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone | 1983 |
Differential effect of chronic desipramine and amitriptyline treatment on rat brain adrenergic and serotonergic receptors.
Topics: Amitriptyline; Animals; Brain; Cerebral Cortex; Clonidine; Desipramine; Dihydroalprenolol; Dioxanes; Male; Radioligand Assay; Rats; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Spiperone | 1981 |
Reduced presynaptic dopamine receptor density after chronic antidepressant treatment in rats.
Topics: Animals; Corpus Striatum; Desipramine; Dopamine; Isoquinolines; Male; Nomifensine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Synapses | 1982 |
An enhanced sensitivity of muscarinic cholinergic receptor associated with dopaminergic receptor subsensitivity after chronic antidepressant treatment.
Topics: Animals; Corpus Striatum; Desipramine; Imipramine; Kinetics; Male; Quinuclidinyl Benzilate; Rats; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Muscarinic; Spiperone; Tritium | 1981 |
Long-term in vivo desipramine or estrogen treatment fails to affect serotonin-induced outward current in hippocampal pyramidal cells of the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Desipramine; Electric Stimulation; Electrophysiology; Estradiol; Estrogens; Female; Hippocampus; In Vitro Techniques; Male; Orchiectomy; Ovariectomy; Potassium Chloride; Pyramidal Cells; Rats; Rats, Wistar; Serotonin; Spiperone; Testosterone | 1994 |
Chronic desipramine treatment influences D1 stimulation and D2 inhibition (dual control) of adenylate cyclase by dopamine in rat striatum.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Benzazepines; Carbachol; Corpus Striatum; Desipramine; Dopamine; Guanosine Triphosphate; Male; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone | 1994 |
Effect of acute, short- and long-term milnacipran administration on rat locus coeruleus noradrenergic and dorsal raphe serotonergic neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Biological Transport; Brimonidine Tartrate; Clonidine; Cyclopropanes; Desipramine; Drug Administration Schedule; gamma-Aminobutyric Acid; Hippocampus; Hypothalamus; Injections, Subcutaneous; Kinetics; Locus Coeruleus; Lysergic Acid Diethylamide; Male; Mesencephalon; Milnacipran; Neurons; Norepinephrine; Quinoxalines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Spiperone; Time Factors | 1998 |