Compounds > spiperone
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spiperone and cysteine

spiperone has been researched along with cysteine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, J; Fu, D; Javitch, JA2
Ballesteros, JA; Chen, J; Fu, D; Javitch, JA; Weinstein, H1
Cravchik, A; Gejman, PV; Hietala, J; Någren, K; Pohjalainen, T; Rinne, J; Syvälahti, E1
Einsiedel, J; Gmeiner, P; Hübner, H1

Other Studies

5 other study(ies) available for spiperone and cysteine

ArticleYear
Differentiating dopamine D2 ligands by their sensitivities to modification of the cysteine exposed in the binding-site crevice.
    Molecular pharmacology, 1996, Volume: 49, Issue:4

    Topics: Benzamides; Binding Sites; Cell Line; Cysteine; Humans; Mutagenesis, Site-Directed; Receptors, Dopamine D2; Spiperone; Structure-Activity Relationship

1996
Residues in the seventh membrane-spanning segment of the dopamine D2 receptor accessible in the binding-site crevice.
    Biochemistry, 1996, Sep-03, Volume: 35, Issue:35

    Topics: Amino Acid Sequence; Binding Sites; Cell Line; Cysteine; Dopamine Antagonists; Ethyl Methanesulfonate; GTP-Binding Proteins; Humans; Kinetics; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Dopamine D2; Signal Transduction; Spiperone; Sulfhydryl Reagents; Sulpiride

1996
Residues in the fifth membrane-spanning segment of the dopamine D2 receptor exposed in the binding-site crevice.
    Biochemistry, 1995, Dec-19, Volume: 34, Issue:50

    Topics: Amino Acid Sequence; Binding Sites; Cysteine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Resistance; Ethyl Methanesulfonate; Humans; Mesylates; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Receptors, Dopamine D2; Spiperone; Sulpiride; Transfection

1995
Antagonist binding characteristics of the Ser311-->Cys variant of human dopamine D2 receptor in vivo and in vitro.
    Biochemical and biophysical research communications, 1997, Mar-06, Volume: 232, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; CHO Cells; Cricetinae; Cysteine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Female; Heterozygote; Humans; Male; Middle Aged; Protein Binding; Raclopride; Radioligand Assay; Receptors, Dopamine D2; Salicylamides; Serine; Spiperone

1997
Benzamide bioisosteres incorporating dihydroheteroazole substructures: EPC synthesis and SAR leading to a selective dopamine D4 receptor partial agonist (FAUC 179).
    Bioorganic & medicinal chemistry letters, 2001, Sep-17, Volume: 11, Issue:18

    Topics: Animals; Biochemistry; Cattle; CHO Cells; Clozapine; Cricetinae; Cysteine; Dopamine Antagonists; Drug Design; Humans; In Vitro Techniques; Indoles; Magnetic Resonance Spectroscopy; Molecular Structure; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D4; Serine; Spiperone; Stereoisomerism; Structure-Activity Relationship; Threonine

2001