Compounds > spiperone
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spiperone and clomipramine

spiperone has been researched along with clomipramine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Artursson, P; Mateus, A; Matsson, P1
Klimek, V; Maj, J; Rawlów, A; Sarnek, J1
Austin, LS; Ballenger, JC; Cohen, BM; Ellinwood, EH; Fossey, MD; Laraia, MT; Lydiard, RB; Zealberg, JJ1
Gee, A; Hosoi, R; Inoue, O; Kobayashi, K1

Trials

1 trial(s) available for spiperone and clomipramine

ArticleYear
Dopamine blocking activity of clomipramine in patients with obsessive-compulsive disorder.
    Biological psychiatry, 1991, Aug-01, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Clomipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Radioligand Assay; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone

1991

Other Studies

5 other study(ies) available for spiperone and clomipramine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
On the anticataleptic action of cyproheptadine.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:2

    Topics: Animals; Atropine; Catalepsy; Clomipramine; Cyproheptadine; Desipramine; Female; Fluphenazine; Humans; Imipramine; Male; Methyltyrosines; Pilocarpine; Pimozide; Promethazine; Rats; Reserpine; Spiperone

1976
Opposing effects of clomipramine on [125I]RTI-55 and [3H]N-methylspiperone binding in mouse striatum: important role of other factors than endogenous dopamine?
    Synapse (New York, N.Y.), 1998, Volume: 30, Issue:3

    Topics: Animals; Brain; Carrier Proteins; Clomipramine; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Organ Specificity; Radioligand Assay; Serotonin; Serotonin Plasma Membrane Transport Proteins; Spiperone; Tritium

1998