spiperone has been researched along with buspirone in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (35.71) | 18.7374 |
| 1990's | 15 (53.57) | 18.2507 |
| 2000's | 2 (7.14) | 29.6817 |
| 2010's | 1 (3.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Newman-Tancredi, A; Strange, PG; Wootton, R | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Fozard, JR; Gittos, MW; Hibert, MF; Middlemiss, DN; Mir, AK | 1 |
| Glennon, RA | 1 |
| Buckingham, J; Glen, RC; Hill, AP; Hyde, RM; Martin, GR; Robertson, AD; Salmon, JA; Woollard, PM | 1 |
| Baldessarini, RJ; Booth, RG; Charifson, PS; Kula, NS; McPhail, AT; Myers, AM; Owens, CE; Wyrick, SD | 1 |
| Amlaiky, N; Hen, R; Plassat, JL | 1 |
| Arrang, JM; Diaz, J; Leurs, R; Ruat, M; Schwartz, JC; Tardivel-Lacombe, J; Traiffort, E | 1 |
| Dokhan, R; el Ahmad, Y; Laurent, E; Maillet, P; Ollivier, R; Talab, A; Teste, JF; Tran, G | 1 |
| Chaput, C; Millan, MJ; Newman-Tancredi, A; Verrièle, L | 1 |
| Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L | 1 |
| Berardi, F; Colabufo, NA; Leopoldo, M; Perrone, R; Tortorella, V | 1 |
| Cleves, AE; Jain, AN; Kirshner, D; Langham, JJ; Spitzer, R | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Newman-Tancredi, A; Strange, PG; Sundaram, H | 1 |
| Colpaert, FC; Millan, MJ | 1 |
| McMillen, BA | 1 |
| Blair, D; Matthews, RT; McMillen, BA; Sallis, R | 1 |
| Anwyl, R; Rowan, MJ | 1 |
| Chamberlain, JK; DaVanzo, JP; McMillen, BA | 1 |
| Lum, JT; Piercey, MF | 1 |
| Baumgarten, HG; Brüning, G; Kaulen, P; Schneider, U | 1 |
| New, JS; Riblet, LA; Taylor, DP; Temple, DL; Yevich, JP | 1 |
| Amano, M; Ishizuka, T; Kubo, T; Ozaki, S; Taguchi, K | 1 |
| Damaj, MI; Glennon, RA; Martin, BR | 1 |
| Christ, G; Kaynan, A; Maayani, S; Melman, A; Rehman, J; Valcic, M | 1 |
| Albert, PR; Ghahremani, MH; Lemonde, S; Sajedi, N | 1 |
| Huryn, D; O'Connor, NA; Paisner, DA; Shea, KJ | 1 |
1 review(s) available for spiperone and buspirone
| Article | Year |
|---|---|
Central serotonin receptors as targets for drug research.
Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin | 1987 |
27 other study(ies) available for spiperone and buspirone
| Article | Year |
|---|---|
High-level stable expression of recombinant 5-HT1A 5-hydroxytryptamine receptors in Chinese hamster ovary cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Binding, Competitive; Blotting, Northern; Cattle; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Gene Expression; Guanosine Triphosphate; Hippocampus; Humans; Receptors, Serotonin; Recombinant Proteins; Tetrahydronaphthalenes; Transfection | 1992 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Graphics computer-aided receptor mapping as a predictive tool for drug design: development of potent, selective, and stereospecific ligands for the 5-HT1A receptor.
Topics: Animals; Computer Graphics; In Vitro Techniques; Ligands; Molecular Conformation; Rats; Receptors, Serotonin; Serotonin Antagonists; Stereoisomerism; Structure-Activity Relationship | 1988 |
Computer-aided design and synthesis of 5-substituted tryptamines and their pharmacology at the 5-HT1D receptor: discovery of compounds with potential anti-migraine properties.
Topics: Animals; Aorta; Computer-Aided Design; Drug Design; Haplorhini; In Vitro Techniques; Migraine Disorders; Models, Chemical; Rabbits; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Saphenous Vein; Serotonin Receptor Agonists; Structure-Activity Relationship; Tryptamines | 1995 |
Conformational analysis, pharmacophore identification, and comparative molecular field analysis of ligands for the neuromodulatory sigma 3 receptor.
Topics: Animals; Ligands; Models, Molecular; Molecular Conformation; Receptors, sigma; Rodentia; Structure-Activity Relationship; Tetrahydronaphthalenes | 1994 |
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Brain; CHO Cells; Cricetinae; Cyclic AMP; DNA; Genomic Library; Kinetics; Lysergic Acid Diethylamide; Mianserin; Molecular Sequence Data; Multigene Family; Oligodeoxyribonucleotides; Organ Specificity; Rats; Receptors, Serotonin; Restriction Mapping; Serotonin; Serotonin Receptor Agonists; Transfection | 1993 |
New benzocycloalkylpiperazines, potent and selective 5-HT1A receptor ligands.
Topics: Adenylyl Cyclases; Animals; Behavior, Animal; Binding, Competitive; Colforsin; Cyclic AMP; Electrophysiology; Enzyme Activation; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Piperazines; Protein Binding; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship | 1997 |
Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Affinity Labels; Animals; Binding, Competitive; CHO Cells; Cricetinae; Guanine Nucleotides; Hippocampus; Humans; Male; Membranes; Piperazines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 1998 |
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes | 1998 |
1-aryl-4-[(5-methoxy-1,2,3, 4-tetrahydronaphthalen-1-yl)alkyl]piperazines and their analogues: influence of the stereochemistry of the tetrahydronaphthalen-1-yl nucleus on 5-HT1A receptor affinity and selectivity versus alpha1 and D2 receptors. 5.
Topics: Animals; CHO Cells; Cricetinae; Gas Chromatography-Mass Spectrometry; Humans; Magnetic Resonance Spectroscopy; Piperazines; Radioligand Assay; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes | 1999 |
Physical binding pocket induction for affinity prediction.
Topics: Binding Sites; Ligands; Models, Molecular; Neural Networks, Computer; Peptide Fragments; Protein Binding; Receptor, Serotonin, 5-HT1A | 2009 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Pharmacological characterisation of the 5-HT1A serotonin receptor using the agonist [3H]8-OH-DPAT, and the antagonist [3H]spiperone.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; CHO Cells; Cricetinae; Humans; Kinetics; Lisuride; Methiothepin; Pindolol; Receptors, Serotonin; Recombinant Proteins; Serotonin; Serotonin Antagonists; Spiperone; Transfection; Tritium | 1992 |
Attenuation of opioid induced antinociception by 5-HT1A partial agonists in the rat.
Topics: Alprenolol; Analgesics; Animals; Buspirone; Fentanyl; Male; Morphine; Narcotics; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Serotonin; Spiperone; Sufentanil | 1990 |
Comparative chronic effects of buspirone or neuroleptics on rat brain dopaminergic neurotransmission.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Body Weight; Buspirone; Dopamine; Female; Haloperidol; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Synaptic Transmission; Time Factors; Trifluoperazine; Tyrosine 3-Monooxygenase | 1985 |
Effects of BMY 14802, a potential antipsychotic drug, on rat brain dopaminergic function.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Brain; Buspirone; Dopamine; Female; Haloperidol; Neurons; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Substantia Nigra; Tyrosine 3-Monooxygenase | 1986 |
Neurophysiological effects of buspirone and isapirone in the hippocampus: comparison with 5-hydroxytryptamine.
Topics: Animals; Anti-Anxiety Agents; Buspirone; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Pyrimidines; Rats; Rats, Inbred Strains; Serotonin; Spiperone | 1986 |
Effects of housing and muricidal behavior on serotonergic receptors and interactions with novel anxiolytic drugs.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Appetitive Behavior; Brain; Buspirone; Male; Mice; Predatory Behavior; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Social Environment; Spiperone | 1988 |
Electrophysiological evidence that spiperone is an antagonist of 5-HT1A receptors in the dorsal raphe nucleus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Buspirone; Dopamine; Electrodes; Electrophysiology; Male; Neurons; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Spiperone; Tetrahydronaphthalenes | 1988 |
Autoradiographic localization of [3H]buspirone binding sites in rat brain.
Topics: Animals; Autoradiography; Brain; Buspirone; Corpus Striatum; Male; Nucleus Accumbens; Olfactory Bulb; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Spiperone | 1985 |
Buspirone analogues. 1. Structure-activity relationships in a series of N-aryl- and heteroarylpiperazine derivatives.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Buspirone; Corpus Striatum; Kinetics; Male; Models, Molecular; Molecular Conformation; Piperazines; Pyrimidines; Rats; Receptors, Dopamine; Spiperone; Structure-Activity Relationship | 1983 |
8-OH-DPAT-induced hypotensive action and sympathoexcitatory neurons in the rostral ventrolateral medulla of the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Buspirone; Heart Rate; Hypotension; Male; Medulla Oblongata; Norepinephrine; Rats; Rats, Wistar; Spiperone | 1995 |
Involvement of the serotonergic system in the hypoactive and antinociceptive effects of nicotine in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Ketanserin; Locomotion; Male; Mice; Mice, Inbred ICR; Nicotine; Nociceptors; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone | 1994 |
Modification of sexual behavior of Long-Evans male rats by drugs acting on the 5-HT1A receptor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Buspirone; Copulation; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Penile Erection; Penis; Piperazines; Pyrimidines; Rats; Rats, Long-Evans; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex; Serotonin; Serotonin Receptor Agonists; Spiperone | 1999 |
Constitutive G(i2)-dependent activation of adenylyl cyclase type II by the 5-HT1A receptor. Inhibition by anxiolytic partial agonists.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Buspirone; Cell Line; Cyclic AMP; Dopamine; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Isoenzymes; Kidney; Kinetics; Pertussis Toxin; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Transfection; Virulence Factors, Bordetella | 1999 |
Screening of 5-HT1A receptor antagonists using molecularly imprinted polymers.
Topics: Binding Sites; Biomimetic Materials; Buspirone; Chromatography, Affinity; Drug Evaluation, Preclinical; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Piperazines; Polymethacrylic Acids; Pyridines; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Static Electricity; Structure-Activity Relationship; Thermodynamics | 2007 |