Page last updated: 2024-08-16

spiperone and 3-n-(2-fluoroethyl)spiperone

spiperone has been researched along with 3-n-(2-fluoroethyl)spiperone in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19906 (24.00)18.7374
1990's11 (44.00)18.2507
2000's8 (32.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, K; Chirakal, R; Firnau, G; Garnett, ES; Nahmias, C1
Coenen, HH; Heiss, WD; Jovkar, S; Pawlik, G; Wienhard, K1
Goffinet, AM; Labar, D; Leysen, J1
Coenen, HH; Heiss, WD; Jovkar, S; Laufer, P; Pawlik, G; Rudolf, J; Stöcklin, G; Wienhard, K1
Barrio, JR; Bida, GT; Huang, SC; Mazziotta, JC; Phelps, ME; Satyamurthy, N1
Coenen, HH; Feinendegen, LE; Herzog, H; Kuwert, T; Langen, KJ1
Coenen, HH; Jovkar, S; Pawlik, G; Wienhard, K1
Ackermann, RF; Bahn, MM; Barrio, JR; Hoffman, JM; Huang, SC; Keen, RE; Mazziotta, JC; Nissenson, CH; Phelps, ME; Satyamurthy, N1
Bahn, MM; Barrio, JR; Hawkins, RA; Hoffman, JM; Huang, SC; Mazziotta, JC; Phelps, ME; Satyamurthy, N2
Böcher-Schwarz, HG; Coenen, HH; Heiss, WD; Laufer, P; Pawlik, G; Stöcklin, G; Wienhard, K1
Coenen, HH; Hebold, I; Heiss, WD; Laufer, P; Pawlik, G; Stöcklin, G; Wienhard, K1
Barrio, JR; Bida, GT; Huang, SC; Luxen, A; Mazziotta, JC; Phelps, ME; Satyamurthy, N1
Bidaut, LM; Giladi, N; Goldman, S; Hildebrand, J; Labar, D; Levivier, M; Luxen, A; Przedborski, S; Stanus, E1
Paans, AM; Pruim, J; Smit, GP; Ullrich, K; Visser, G; Willemsen, AT1
Bettinardi, V; Del Sole, A; Fazio, F; Giovanelli, M; Losa, M; Lucignani, G; Matarrese, M; Moresco, RM; Mortini, P1
Barrio, JR; Berk, AJ; Cherry, SR; Gambhir, SS; Herschman, HR; MacLaren, DC; Phelps, ME; Satyamurthy, N; Sharfstein, S; Toyokuni, T; Wu, L1
Bonfanti, A; Colombo, C; Del Sole, A; Fazio, F; Galli, L; Gobbo, C; Lucca, A; Lucignani, G; Messa, C; Moresco, RM; Smeraldi, E1
Artigas, F; Colombo, C; Fazio, F; Gobbo, C; Messa, C; Moresco, R; Smeraldi, E; Zanardi, R1
Barrio, JR; Gambhir, SS; Herschman, HR; Liang, Q; Namavari, M; Phelps, ME; Satyamurthy, N; Toyokuni, T; Wu, L; Yaghoubi, SS1
Alenius, S; Bettinardi, V; Fazio, F; Gilardi, MC; Pagani, E; Teras, M; Thielemans, K1
De Peri, L; Dieci, M; Fazio, F; Galli, L; Gobbo, C; Invernizzi, G; Messa, C; Moresco, FM; Panzacchi, A; Rizzo, G; Vita, A1
Artigas, F; Colombo, C; Fazio, F; Galli, L; Gilardi, MC; Gobbo, C; Lucignani, G; Messa, C; Moresco, RM; Rizzo, G; Smeraldi, E; Zanardi, R1
Chen, IY; Gambhir, SS; Herschman, HR; Lewis, X; Liang, Q; Min, JJ; Sundaresan, G; Wu, JC1
Bravi, D; Cavallaro, R; Colombo, C; Fazio, F; Galli, L; Gobbo, C; Lucignani, G; Messa, C; Moresco, RM; Rizzo, G; Smeraldi, E; Velonà, I1

Reviews

1 review(s) available for spiperone and 3-n-(2-fluoroethyl)spiperone

ArticleYear
New 18F tracers for the investigation of brain functions.
    Acta radiologica. Supplementum, 1990, Volume: 374

    Topics: Brain; Dihydroxyphenylalanine; Fluorine Radioisotopes; Humans; Hydrocarbons, Fluorinated; Spiperone; Tomography, Emission-Computed

1990

Trials

2 trial(s) available for spiperone and 3-n-(2-fluoroethyl)spiperone

ArticleYear
Effects of fluvoxamine treatment on the in vivo binding of [F-18]FESP in drug naive depressed patients: a PET study.
    NeuroImage, 2000, Volume: 12, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Brain; Depressive Disorder, Major; Female; Fluorine Radioisotopes; Fluvoxamine; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Spiperone; Tissue Distribution; Tomography, Emission-Computed

2000
Cerebral D2 and 5-HT2 receptor occupancy in Schizophrenic patients treated with olanzapine or clozapine.
    Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brain; Clozapine; Double-Blind Method; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Olanzapine; Positron-Emission Tomography; Prospective Studies; Receptors, Dopamine D2; Receptors, Serotonin, 5-HT2; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Spiperone

2004

Other Studies

22 other study(ies) available for spiperone and 3-n-(2-fluoroethyl)spiperone

ArticleYear
Quantification of baboon cortical S2 serotonin receptors in vivo with 3-N-(2'-F18)fluoroethylspiperone and positron emission tomography.
    European journal of nuclear medicine, 1991, Volume: 18, Issue:3

    Topics: Animals; Brain; Frontal Lobe; Male; Papio; Receptors, Serotonin; Spiperone; Tomography, Emission-Computed

1991
In vitro pharmacological profile of 3-N-(2-fluoroethyl)spiperone.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1990, Volume: 10, Issue:1

    Topics: Animals; Brain; Chemical Phenomena; Chemistry; Guinea Pigs; In Vitro Techniques; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Spiperone

1990
PET studies of dopamine receptor distribution using [18F]fluoroethylspiperone: findings in disorders related to the dopaminergic system.
    Journal of neural transmission. General section, 1990, Volume: 81, Issue:3

    Topics: Adolescent; Adult; Aged; Brain; Caudate Nucleus; Female; Humans; Male; Middle Aged; Nervous System Diseases; Parkinson Disease; Receptors, Dopamine; Receptors, Dopamine D2; Schizophrenia; Spiperone; Tomography, Emission-Computed

1990
3-(2'-[18F]fluoroethyl)spiperone, a potent dopamine antagonist: synthesis, structural analysis and in-vivo utilization in humans.
    International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 1990, Volume: 41, Issue:2

    Topics: Brain; Chemical Phenomena; Chemistry; Dopamine Antagonists; Fluorine Radioisotopes; Humans; Receptors, Dopamine; Spiperone; Tomography, Emission-Computed

1990
Quantification of the whole-body distribution of PET radiopharmaceuticals, applied to 3-N-([18F]fluoroethyl)spiperone.
    European journal of nuclear medicine, 1990, Volume: 16, Issue:2

    Topics: Brain; Fluorine Radioisotopes; Humans; Spiperone; Tissue Distribution; Tomography, Emission-Computed

1990
The quantitative analysis of D2-dopamine receptors in baboon striatum in vivo with 3-N-[2'-18F]fluoroethylspiperone using positron emission tomography.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1990, Volume: 10, Issue:5

    Topics: Animals; Corpus Striatum; Kinetics; Male; Models, Neurological; Papio; Receptors, Dopamine; Spiperone; Tomography, Emission-Computed

1990
3-(2'-[18F]fluoroethyl)spiperone: in vivo biochemical and kinetic characterization in rodents, nonhuman primates, and humans.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1989, Volume: 9, Issue:6

    Topics: Animals; Autoradiography; Brain; Corpus Striatum; Fluorine Radioisotopes; Humans; Kinetics; Macaca nemestrina; Male; Mice; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Species Specificity; Spiperone; Tissue Distribution; Tomography, Emission-Computed; Tritium

1989
Models for in vivo kinetic interactions of dopamine D2-neuroreceptors and 3-(2'-[18F]fluoroethyl)spiperone examined with positron emission tomography.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1989, Volume: 9, Issue:6

    Topics: Adult; Animals; Brain; Corpus Striatum; Fluorine Radioisotopes; Humans; Kinetics; Macaca nemestrina; Male; Mathematics; Models, Biological; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Tomography, Emission-Computed

1989
A double-injection technique for in vivo measurement of dopamine D2-receptor density in monkeys with 3-(2'-[18F]fluoroethyl)spiperone and dynamic positron emission tomography.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1989, Volume: 9, Issue:6

    Topics: Animals; Corpus Striatum; Fluorine Radioisotopes; Injections, Intravenous; Kinetics; Macaca nemestrina; Mathematics; Models, Neurological; Models, Theoretical; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Tomography, Emission-Computed

1989
3-N-(2-[18F]-fluoroethyl)-spiperone: a novel ligand for cerebral dopamine receptor studies with pet.
    Life sciences, 1987, Jan-05, Volume: 40, Issue:1

    Topics: Animals; Cerebellum; Corpus Striatum; Fluorine; Male; Mice; Papio; Radioisotopes; Radioligand Assay; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Tomography, Emission-Computed

1987
PET measurement of D2 and S2 receptor binding of 3-N-[( 2'-18F]fluoroethyl)spiperone in baboon brain.
    European journal of nuclear medicine, 1988, Volume: 14, Issue:2

    Topics: Animals; Brain; Cerebellum; Corpus Striatum; Fluorine Radioisotopes; Male; Papio; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Spiperone; Tomography, Emission-Computed

1988
No-carrier-added 3-(2'-[18F]fluoroethyl)spiperone, a new dopamine receptor-binding tracer for positron emission tomography.
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1986, Volume: 13, Issue:6

    Topics: Animals; Brain; Kinetics; Macaca nemestrina; Receptors, Dopamine; Spiperone; Tomography, Emission-Computed

1986
Brain glucose metabolism and dopamine D2 receptor analysis in a patient with hemiparkinsonism-hemiatrophy syndrome.
    Movement disorders : official journal of the Movement Disorder Society, 1993, Volume: 8, Issue:3

    Topics: Aged; Basal Ganglia; Brain; Corpus Striatum; Diagnosis, Differential; Female; Functional Laterality; Glucose; Humans; Parkinson Disease; Receptors, Dopamine D2; Spiperone; Tomography, Emission-Computed

1993
Neurotransmitter positron emission tomographic-studies in adults with phenylketonuria, a pilot study.
    European journal of pediatrics, 1996, Volume: 155 Suppl 1

    Topics: Adolescent; Adult; Brain; Carbon Radioisotopes; Female; Humans; Male; Phenylalanine; Phenylketonurias; Pilot Projects; Spiperone; Tomography, Emission-Computed; Tyrosine

1996
Differentiation of clinically non-functioning pituitary adenomas from meningiomas and craniopharyngiomas by positron emission tomography with [18F]fluoro-ethyl-spiperone.
    European journal of nuclear medicine, 1997, Volume: 24, Issue:9

    Topics: Adenoma; Adolescent; Aged; Craniopharyngioma; Diagnosis, Differential; Female; Fluorine Radioisotopes; Humans; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Pituitary Neoplasms; Spiperone; Tomography, Emission-Computed

1997
Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals.
    Gene therapy, 1999, Volume: 6, Issue:5

    Topics: Adenoviridae; Animals; Dopamine Antagonists; Fluorescent Dyes; Gene Expression; Genes, Reporter; Genetic Vectors; Liver; Male; Mice; Mice, Nude; Mice, Transgenic; Neoplasms, Experimental; Radioligand Assay; Receptors, Dopamine D2; RNA, Messenger; Spiperone; Tomography, Emission-Computed

1999
Increased 5-hydroxytryptamine-2 receptor binding in the frontal cortex of depressed patients responding to paroxetine treatment: a positron emission tomography scan study.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:1

    Topics: Adult; Depression; Female; Fluorine Radioisotopes; Humans; Male; Paroxetine; Prefrontal Cortex; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Spiperone; Tomography, Emission-Computed; Treatment Outcome

2001
Direct correlation between positron emission tomographic images of two reporter genes delivered by two distinct adenoviral vectors.
    Gene therapy, 2001, Volume: 8, Issue:14

    Topics: Adenoviridae; Animals; Cells, Cultured; COS Cells; Cytomegalovirus; Feasibility Studies; Gene Expression; Genetic Vectors; Guanine; Herpesvirus 1, Human; Liver; Mice; Mice, Inbred Strains; Mice, Nude; Promoter Regions, Genetic; Rats; Receptors, Dopamine D2; Spiperone; Thymidine Kinase; Time Factors; Tomography, Emission-Computed

2001
Implementation and evaluation of a 3D one-step late reconstruction algorithm for 3D positron emission tomography brain studies using median root prior.
    European journal of nuclear medicine and molecular imaging, 2002, Volume: 29, Issue:1

    Topics: Algorithms; Brain; Caudate Nucleus; Fluorodeoxyglucose F18; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Phantoms, Imaging; Putamen; Radiopharmaceuticals; Spiperone; Tomography, Emission-Computed

2002
In vivo serotonin 5HT(2A) receptor binding and personality traits in healthy subjects: a positron emission tomography study.
    NeuroImage, 2002, Volume: 17, Issue:3

    Topics: Adult; Avoidance Learning; Basal Ganglia; Brain Mapping; Cerebral Cortex; Female; Humans; Image Processing, Computer-Assisted; Male; Personality; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Reference Values; Spiperone; Tomography, Emission-Computed

2002
5-HT(2A) receptor binding is reduced in drug-naive and unchanged in SSRI-responder depressed patients compared to healthy controls: a PET study.
    Psychopharmacology, 2003, Volume: 167, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Brain; Case-Control Studies; Depressive Disorder, Major; Dopamine Antagonists; Female; Fluorine Radioisotopes; Humans; Ligands; Male; Middle Aged; Paroxetine; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Spiperone; Tomography, Emission-Computed

2003
Micro-positron emission tomography imaging of cardiac gene expression in rats using bicistronic adenoviral vector-mediated gene delivery.
    Circulation, 2004, Mar-23, Volume: 109, Issue:11

    Topics: Adenoviridae; Animals; Cells, Cultured; Defective Viruses; Fluorine Radioisotopes; Gene Expression Regulation, Viral; Genes, Reporter; Genetic Therapy; Genetic Vectors; Guanine; Heart; Herpesvirus 1, Human; Injections; Myocardium; Myocytes, Cardiac; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Nude; Rats, Sprague-Dawley; Receptors, Dopamine D2; Recombinant Fusion Proteins; Spiperone; Thymidine Kinase; Transduction, Genetic

2004