spiperone has been researched along with 1-(3-chlorophenyl)piperazine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (21.05) | 18.7374 |
| 1990's | 10 (52.63) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamblin, MW; Metcalf, MA | 1 |
| Glennon, RA | 2 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Mutel, V; Sleight, AJ; Stam, NJ; Vanderheyden, PM | 1 |
| Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB | 1 |
| Conklin, DS; Fitzgerald, LW; Hartig, PR; Iyer, G; Kostich, WA; Krause, CM; Largent, BL; Marshall, AP; Patterson, JP; Tran, DP | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Cleves, AE; Jain, AN; Kirshner, D; Langham, JJ; Spitzer, R | 1 |
| Aulakh, CS; Hill, JL; Murphy, DL | 1 |
| Aulakh, CS; Lesch, KP; Murphy, DL; Pigott, TA | 1 |
| Aghajanian, GK; Sheldon, PW | 1 |
| Bobker, DH; Williams, JT | 1 |
| Jenner, P; Marsden, CD; Stewart, BR | 1 |
| Brazell, C; Dourish, CT; King, BH; Middlemiss, DN | 1 |
| Chojnacka-Wójcik, E; Jaros, T; Kłodzińska, A; Maj, J | 1 |
| Jeffrey, JJ; Rydelek-Fitzgerald, L; Teitler, M; Wilcox, BD | 1 |
| Calama, E; Martín, ML; Morán, A; Ortiz de Urbina, AV; San Román, L | 1 |
| Clifton, PG; Dourish, CT; Kennett, GA; Lee, MD; Somerville, EM | 1 |
3 review(s) available for spiperone and 1-(3-chlorophenyl)piperazine
| Article | Year |
|---|---|
Central serotonin receptors as targets for drug research.
Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin | 1987 |
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
Serotonin-selective arylpiperazines with neuroendocrine, behavioral, temperature, and cardiovascular effects in humans.
Topics: Animals; Aza Compounds; Behavior, Animal; Body Temperature; Cardiovascular System; Dementia; Humans; Neurotic Disorders; Piperazines; Receptors, Serotonin; Spiperone | 1991 |
16 other study(ies) available for spiperone and 1-(3-chlorophenyl)piperazine
| Article | Year |
|---|---|
Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cyclic AMP; GTP-Binding Proteins; Humans; Molecular Sequence Data; Pertussis Toxin; Receptors, Serotonin; Virulence Factors, Bordetella | 1991 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
Radiolabelling of the human 5-HT2A receptor with an agonist, a partial agonist and an antagonist: effects on apparent agonist affinities.
Topics: 3T3 Cells; Animals; Binding, Competitive; Cell Membrane; DOM 2,5-Dimethoxy-4-Methylamphetamine; Humans; Ketanserin; Mice; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Recombinant Proteins; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1996 |
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor.
Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine | 1998 |
High-affinity agonist binding correlates with efficacy (intrinsic activity) at the human serotonin 5-HT2A and 5-HT2C receptors: evidence favoring the ternary complex and two-state models of agonist action.
Topics: Amphetamines; Binding, Competitive; Cell Line; Ergolines; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydrolysis; Isomerism; Ligands; Models, Biological; Phosphatidylinositols; Receptors, Serotonin; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone | 1999 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Physical binding pocket induction for affinity prediction.
Topics: Binding Sites; Ligands; Models, Molecular; Neural Networks, Computer; Peptide Fragments; Protein Binding; Receptor, Serotonin, 5-HT1A | 2009 |
Effects of various serotonin receptor subtype-selective antagonists alone and on m-chlorophenylpiperazine-induced neuroendocrine changes in rats.
Topics: Animals; Corticosterone; Ergolines; Male; Metergoline; Mianserin; Neurosecretory Systems; Piperazines; Prolactin; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiperone | 1992 |
Excitatory responses to serotonin (5-HT) in neurons of the rat piriform cortex: evidence for mediation by 5-HT1C receptors in pyramidal cells and 5-HT2 receptors in interneurons.
Topics: Animals; Electrophysiology; Ergolines; Interneurons; Limbic System; Male; Neurons; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Spiperone | 1991 |
Serotonin-mediated inhibitory postsynaptic potential in guinea-pig prepositus hypoglossi and feedback inhibition by serotonin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Brain Stem; Dose-Response Relationship, Drug; Feedback; Guinea Pigs; Hypoglossal Nerve; In Vitro Techniques; Male; Neurons; Piperazines; Potassium; Serotonin; Spiperone; Synapses; Tetrahydronaphthalenes; Time Factors | 1990 |
Induction of purposeless chewing behaviour in rats by 5-HT agonist drugs.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Male; Methiothepin; Methoxydimethyltryptamines; Mianserin; Parasympatholytics; Piperazines; Propranolol; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes | 1989 |
MK-212 increases rat plasma ACTH concentration by activation of the 5-HT1C receptor subtype.
Topics: Adrenocorticotropic Hormone; Animals; Antiparkinson Agents; Ergolines; Ketanserin; Male; Metergoline; Pindolol; Piperazines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone | 1989 |
Exploratory hypoactivity induced by m-trifluoromethylphenylpiperazine (TFMPP) and m-chlorophenylpiperazine (m-CPP).
Topics: Animals; Ergolines; Exploratory Behavior; Male; Metergoline; Mianserin; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone | 1989 |
Serotonin-mediated 5-HT2 receptor gene regulation in rat myometrial smooth muscle cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Biguanides; Cells, Cultured; Cycloheximide; Female; Gene Expression Regulation; Ketanserin; Medroxyprogesterone Acetate; Myometrium; Piperazines; Quipazine; Rats; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sulpiride; Transcription, Genetic; Up-Regulation | 1993 |
Vasoconstrictor responses to 5-hydroxytryptamine in the autoperfused hindquarters of spontaneously hypertensive rats.
Topics: Animals; Dose-Response Relationship, Drug; Hindlimb; Indoles; Injections, Intra-Arterial; Injections, Intravenous; Male; Perfusion; Piperazines; Prazosin; Pyridines; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT2; Regional Blood Flow; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Spiperone; Thiophenes; Vasoconstriction | 2004 |
Reduced hypophagic effects of d-fenfluramine and the 5-HT2C receptor agonist mCPP in 5-HT1B receptor knockout mice.
Topics: Animals; Binding Sites; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Eating; Ergolines; Fenfluramine; Genotype; Injections, Intraperitoneal; Injections, Subcutaneous; Isomerism; Mianserin; Mice; Mice, Knockout; Piperazines; Piperidones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Satiation; Satiety Response; Serotonin 5-HT2 Receptor Agonists; Species Specificity; Spiperone; Spiro Compounds; Time Factors; Tritium; United Kingdom | 2004 |