Page last updated: 2024-09-04

spinosin and 8-hydroxy-2-(di-n-propylamino)tetralin

spinosin has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 2 studies

Compound Research Comparison

Studies (spinosin)	Trials (spinosin)	Recent Studies (post-2010) (spinosin)	Studies (8-hydroxy-2-(di-n-propylamino)tetralin)	Trials (8-hydroxy-2-(di-n-propylamino)tetralin)	Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin)
39	0	30	3,530	7	389

Protein Interaction Comparison

Protein	Taxonomy	8-hydroxy-2-(di-n-propylamino)tetralin (IC50)
5-hydroxytryptamine receptor 1A	Homo sapiens (human)	0.0012
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	0.0032
Alpha-2B adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
D(2) dopamine receptor	Bos taurus (cattle)	0.8
Alpha-2C adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
Alpha-2A adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
D(2) dopamine receptor	Rattus norvegicus (Norway rat)	2.8959
Lysosomal alpha-glucosidase	Bos taurus (cattle)	0.0021

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bai, YJ; Cao, JX; Cui, SY; Cui, XY; Wang, LE; Zhang, J; Zhang, QY; Zhang, YH; Zhao, YY	1
Wang, LE; Yin, YQ; Zhang, XQ; Zhang, YH	1

Other Studies

2 other study(ies) available for spinosin and 8-hydroxy-2-(di-n-propylamino)tetralin

Article	Year
Potentiating effect of spinosin, a C-glycoside flavonoid of Semen Ziziphi spinosae, on pentobarbital-induced sleep may be related to postsynaptic 5-HT(1A) receptors. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Drug Synergism; Drug Therapy, Combination; Drugs, Chinese Herbal; Flavonoids; Glycosides; Male; Monosaccharides; Pentobarbital; Phytotherapy; Piperazines; Rats; Rats, Sprague-Dawley; Seeds; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Sleep; Sleep Initiation and Maintenance Disorders; Sleep, REM; Time Factors; Wakefulness; Ziziphus	2010
Augmentative effect of spinosin on pentobarbital-induced loss of righting reflex in mice associated with presynaptic 5-HT1A receptor. The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Aminopyridines; Analysis of Variance; Animals; Drugs, Chinese Herbal; Flavonoids; Hypothermia; Male; Mice; Mice, Inbred ICR; Pentobarbital; Piperazines; Receptor, Serotonin, 5-HT1A; Receptors, Presynaptic; Reflex, Righting; Serotonin Receptor Agonists	2012

Article

Year

Potentiating effect of spinosin, a C-glycoside flavonoid of Semen Ziziphi spinosae, on pentobarbital-induced sleep may be related to postsynaptic 5-HT(1A) receptors.

Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:6

Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Drug Synergism; Drug Therapy, Combination; Drugs, Chinese Herbal; Flavonoids; Glycosides; Male; Monosaccharides; Pentobarbital; Phytotherapy; Piperazines; Rats; Rats, Sprague-Dawley; Seeds; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Sleep; Sleep Initiation and Maintenance Disorders; Sleep, REM; Time Factors; Wakefulness; Ziziphus

2010

Augmentative effect of spinosin on pentobarbital-induced loss of righting reflex in mice associated with presynaptic 5-HT1A receptor.

The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:2

Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Aminopyridines; Analysis of Variance; Animals; Drugs, Chinese Herbal; Flavonoids; Hypothermia; Male; Mice; Mice, Inbred ICR; Pentobarbital; Piperazines; Receptor, Serotonin, 5-HT1A; Receptors, Presynaptic; Reflex, Righting; Serotonin Receptor Agonists

2012