Page last updated: 2024-09-02

spinasterol and stigmasterol

spinasterol has been researched along with stigmasterol in 60 studies

Compound Research Comparison

Studies
(spinasterol)
Trials
(spinasterol)
Recent Studies (post-2010)
(spinasterol)
Studies
(stigmasterol)
Trials
(stigmasterol)
Recent Studies (post-2010) (stigmasterol)
660289197426

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-19907 (11.67)18.7374
1990's8 (13.33)18.2507
2000's14 (23.33)29.6817
2010's29 (48.33)24.3611
2020's2 (3.33)2.80

Authors

AuthorsStudies
Han, L; Ni, MY1
Yuan, AX1
Liu, JY; Lu, CY; Luo, SQ; Sun, XB; Zhou, CC1
Hirota, K; Ishikawa, Y; Mizuno, H; Takeda, K; Takeuchi, N; Uchida, K1
Takido, M; Yamanouchi, S; Yasukawa, K1
Li, P; Ma, Y; Tang, X1
Bremner, JB; Lemon, P; Palileo, A; Villaseñor, IM1
Chen, Y; Liang, N; Wei, J; Zhu, Y1
Ghosh, P; Patterson, GW; Wikfors, GH1
Chen, Y; Li, B; Wang, M; Zhang, J1
Domingo, AP; Villaseñor, IM1
Liang, H; Wei, S; Zhang, R; Zhao, Y1
Guo, D; Liu, J; Min, D; Wang, S; Xu, L; Zhang, Z; Zheng, K1
Athukoralage, PS; Herath, HM; Jamie, JF1
Ding, X; Luo, H; Yang, S; Zhong, Y; Zuo, C1
KUBOTA, T; MATSUI, Y; TAKEDA, K1
WALTER, ED1
Jeon, GC; Park, MS; Shin, CH; Sin, HS; Um, SJ; Yoon, DY1
Coelho, DS; Freire, CS; Pascoal Neto, C; Santos, NM; Silvestre, AJ1
Sun, HD; Wu, JZ; Zhao, XY1
Xu, LZ; Yang, SL; Yang, XD; Zhang, LJ; Zou, ZM1
Ardenghi, JV; d' Avila Moura, J; Junior, AC; Meotti, FC; Pizzolatti, MG; Pretto, JB; Santos, AR; Soldi, C; Souza, MM1
Sun, JY; Wang, B; Yin, JT; Zhong, Y; Zuo, CX1
Chen, PD; Lu, TL1
Huang, X; Kong, L; Liu, R; Yao, S1
Bessoule, JJ; Carde, JP; Cullimore, J; Furt, F; Hartmann, MA; Lefebvre, B; Michaelson, LV; Mongrand, S; Napier, JA; Rossignol, M; Sargueil-Boiron, F1
Liu, XX; Qiu, B; Wang, L; Wang, Q1
Bai, S; Chen, Q; Mou, MY; Pi, K; Yao, RJ; Zhang, QJ1
Baggio, CH; Dos Santos, AC; Dos Santos, EP; Freitas, CS; Luiz, AP; Marcon, R; Marques, MC; Mayer, B; Pizzolatti, MG; Santos, AR; Soldi, C; Twardowschy, A1
Mahadevan, KM; Manjunatha, H; Ravikumar, YS; Satyanarayana, ND1
Cechinel Filho, V; de Andrade, SF; Gandolfi, RB; Klein, LC; Lemos, M; Santin, JR1
Boller, S; Cabrini, DA; Marques, MC; Otuki, MF; Pizzolatti, MG; Santos, EP; Soldi, C; Zampronio, AR1
Camacho-Carranza, R; Cárdenas-Rodríguez, N; Coballase-Urrutia, E; Delgado-Lamas, G; Espinosa-Aguirre, JJ; Huerta-Gertrudis, B; Medina-Campos, ON; Mendoza-Cruz, M; Pedraza-Chaverri, J1
Jeong, GS; Kim, KH; Kim, YC; Lee, DS; Lee, IK; Lee, KR; Li, B1
Csupor-Löffler, B; Forgo, P; Hajdú, Z; Hohmann, J; Kele, Z; Molnár, J; Vasas, A; Zupkó, I1
Kim, HP; Kwon, YS; Lim, H; Park, HY1
Baek, NI; Chung, DK; Kim, J; Lee, DY; Lee, SM; Lee, TH; Son, Y1
Liu, DX; Wang, WY; Zhao, SC1
Bresolin, TM; Cechinel-Filho, V; Klein-Júnior, LC; Meira, NA; Quintão, NL1
Bang, MH; Chung, DK; Jung, M; Kim, J; Lee, TH1
Athayde, ML; Boligon, AA; Ferreira, J; Guerra, GP; Klafke, JZ; Oliveira, SM; Rosa, F; Rossato, MF; Tonello, R; Trevisan, G; Walker, CI; Zanon, RB1
Chen, AM; Liu, JS; Wang, G; Xu, YS; Zhang, CE1
Borges, FR; Córdova, MM; Pizzolatti, MG; Santos, AR; Schambach, TR; Silva, MD1
Andreoletti, P; Cherkaoui-Malki, M; El Hajj, HI; El Kebbaj, MS; El Kebbaj, R; El Kharrassi, Y; Latruffe, N; Lizard, G; Lopez, T; Masson, D; Moustaid, K; Nasser, B; Nury, T; Samadi, M; Vamecq, J1
Kyoung, H; Lee, MY; Seo, CS; Shin, HK; Shin, IS; Son, JK1
Badreddine, A; Cherkaoui Malki, M; El Kharrassi, Y; Karym, el M; Lizard, G; Nasser, B; Nury, T; Samadi, M; Zarrouk, A1
Nieoczym, D; Pieróg, M; Socała, K; Wlaź, P1
Cai, BX; Liu, JS; Wang, G; Wang, GK; Wang, Z; Zhang, CE1
Cimmino, A; De Carvalho, A; Evidente, A; Evidente, M; Ferderin, M; Kiss, R; Masi, M; Mathieu, V; Moreno Y Banuls, L1
Socała, K; Wlaź, P1
Dou, LL; Li, P; Li, SZ; Liu, EH; Liu, LL; Wu, W; Yu, KY1
Cai, Y; Chen, H; Dong, Q; Li, Y; Rong, Q; Shi, F; Tang, H; Wang, T; Xu, M; Yang, X; Ye, G; Zhao, L; Zhou, J; Zhou, X1
Haralampiev, I; Huster, D; Müller, P; Scheidt, HA1
Brusco, I; Camponogara, C; Carvalho, FB; Ferreira, J; Oliveira, MS; Oliveira, SM; Schetinger, MRC; Trevisan, G1
Liu, JS; Wang, G; Wang, GK; Wang, Z; Yu, Y; Zhang, N; Zhou, ZY1
Arafa, RK; El Gammal, ZH; El-Badri, N; El-Fallal, AA; Mosad, E; Sedky, NK; Wahba, AE; Waly, ZY1
Adebiyi, OE; Olayemi, FO; Olopade, JO1
Chaicharoenpong, C; Chunhakant, S1
Ahmed, M; Ahsan, T; Aslam, M; Hussain, D; Javeed, A; Ji, M; Li, X; Mateen, A; Qin, P; Sajid, AR1
Ahmad, F; Appian, S; Majeed, M; Mundkur, L1

Reviews

1 review(s) available for spinasterol and stigmasterol

ArticleYear
Pharmacology of α-spinasterol, a phytosterol with nutraceutical values: A review.
    Phytotherapy research : PTR, 2022, Volume: 36, Issue:10

    Topics: Anti-Inflammatory Agents; Cytokines; Dietary Supplements; Glucose; Humans; Hypoglycemic Agents; Phytosterols; Plant Oils; Prostaglandin-Endoperoxide Synthases; Stigmasterol

2022

Other Studies

59 other study(ies) available for spinasterol and stigmasterol

ArticleYear
[Studies on the chemical constituents of Ardisia crenata Sims].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1989, Volume: 14, Issue:12

    Topics: Benzopyrans; Chemical Phenomena; Chemistry; Drugs, Chinese Herbal; Sitosterols; Stigmasterol; Sucrose

1989
[Chemical constituents of Drymaria cordata].
    Zhong yao tong bao (Beijing, China : 1981), 1987, Volume: 12, Issue:1

    Topics: Medicine, Chinese Traditional; Medicine, East Asian Traditional; Nitrates; Phytosterols; Plants, Medicinal; Potassium Compounds; Stigmasterol; Succinates; Succinic Acid

1987
[Anti-inflammatory effect of alpha-spinasterol].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1985, Volume: 20, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Capillary Permeability; Edema; Female; Foot Diseases; Male; Mice; Phytosterols; Rats; Stigmasterol

1985
Effects of spinasterol and sitosterol on plasma and liver cholesterol levels and biliary and fecal sterol and bile acid excretions in mice.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:1

    Topics: Animals; Bile; Bile Acids and Salts; Body Weight; Cholesterol; Feces; Liver; Male; Mice; Phospholipids; Phytosterols; Sitosterols; Sterols; Stigmasterol

1983
[Studies on the constituents in the water extracts of crude drugs. III. On the roots of Stellaria dichotoma L. var. lanceolata Bge. (author's transl)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1981, Volume: 101, Issue:1

    Topics: Plant Extracts; Plants, Medicinal; Sitosterols; Stigmasterol

1981
[Separation and identification of the anti-inflammatory diterpene from the root cortices of Acanthopanax gracilistylus W. W. Smith].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1995, Volume: 20, Issue:4

    Topics: Anti-Inflammatory Agents; Diterpenes; Drugs, Chinese Herbal; Plant Roots; Plants, Medicinal; Stigmasterol

1995
Antigenotoxic spinasterol from Cucurbita maxima flowers.
    Mutation research, 1996, Jun-10, Volume: 360, Issue:2

    Topics: Animals; Antimutagenic Agents; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Micronucleus Tests; Spectrophotometry, Infrared; Stigmasterol; Vegetables

1996
[Chemical components of Codonopsis pilosula (Franch.) Nannf. var. volubilis (Nannf.) L.T. Shen].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1995, Volume: 20, Issue:10

    Topics: Drugs, Chinese Herbal; Fructose; Stigmasterol

1995
Use of an improved internal-standard method in the quantitative sterol analyses of phytoplankton and oysters.
    Lipids, 1997, Volume: 32, Issue:9

    Topics: Animals; Cholesterol; Cholesterol Esters; Ostreidae; Phytoplankton; Reference Standards; Sterols; Stigmasterol

1997
[Chemical constituents of Aster poliothamnus Diels].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1997, Volume: 22, Issue:2

    Topics: Asteraceae; Molecular Conformation; Plants, Medicinal; Stigmasterol; Triterpenes

1997
Anticarcinogenicity potential of spinasterol isolated from squash flowers.
    Teratogenesis, carcinogenesis, and mutagenesis, 2000, Volume: 20, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Chloroform; Chromatography, Liquid; Cocarcinogenesis; Croton Oil; Cucurbitaceae; Drug Screening Assays, Antitumor; Methanol; Mice; Molecular Structure; Skin Neoplasms; Solvents; Stigmasterol; Time Factors

2000
[Separation and identification of the compounds from Achyranthes bidentata Bl].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1997, Volume: 22, Issue:5

    Topics: Anthraquinones; Drugs, Chinese Herbal; Magnoliopsida; Molecular Structure; Plants, Medicinal; Sitosterols; Stigmasterol

1997
[Chemical constituents of Conyza blinii Lévl].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1998, Volume: 23, Issue:5

    Topics: Asteraceae; Caffeic Acids; Drugs, Chinese Herbal; Plant Shoots; Plants, Medicinal; Quercetin; Stigmasterol

1998
A new oleanane triterpenoid from Gordonia ceylanica.
    Natural product letters, 2001, Volume: 15, Issue:5

    Topics: Chromatography, Liquid; Chromatography, Thin Layer; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Plant Stems; Plants, Medicinal; Spectrophotometry, Infrared; Spectrum Analysis; Sri Lanka; Stigmasterol; Theaceae; Triterpenes

2001
[Studies on chemical constituents of the roots of Gypsophila oldhamiana Miq].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1999, Volume: 24, Issue:11

    Topics: Caryophyllaceae; Plant Roots; Plants, Medicinal; Sitosterols; Stigmasterol

1999
Bile acids and steroids. X. On beta-spinasterol.
    Chemical & pharmaceutical bulletin, 1958, Volume: 6, Issue:4

    Topics: Bile Acids and Salts; Humans; Steroids; Stigmasterol

1958
ISOLATION OF ALPHA-SPINASTERYL-D-GLUCOSIDE AND ALPHA-SPINASTEROL FROM ALFALFA.
    Journal of pharmaceutical sciences, 1964, Volume: 53

    Topics: Chemistry Techniques, Analytical; Glucosides; Glycosides; Medicago sativa; Palmitic Acid; Research; Sterols; Stigmasterol

1964
Antitumor activity of spinasterol isolated from Pueraria roots.
    Experimental & molecular medicine, 2005, Apr-30, Volume: 37, Issue:2

    Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Humans; Plant Preparations; Plant Roots; Pueraria; Stigmasterol; Transfection; Tumor Cells, Cultured

2005
Identification of delta7 phytosterols and phytosteryl glucosides in the wood and bark of several Acacia species.
    Lipids, 2005, Volume: 40, Issue:3

    Topics: Acacia; Gas Chromatography-Mass Spectrometry; Glucosides; Phytosterols; Plant Stems; Portugal; Sitosterols; Stigmasterol; Wood

2005
[Studies on chemical constituents from rhizome of Impatiens pritzellii var. hupehensis].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:8

    Topics: Impatiens; Plants, Medicinal; Rhizome; Stearic Acids; Stigmasterol

2005
A new sterol glycoside from Securidaca inappendiculata.
    Journal of Asian natural products research, 2005, Volume: 7, Issue:4

    Topics: Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Roots; Securidaca; Stigmasterol

2005
Antinociceptive properties of coumarins, steroid and dihydrostyryl-2-pyrones from Polygala sabulosa (Polygalaceae) in mice.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:1

    Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Coumarins; Male; Mice; Pain Measurement; Plant Extracts; Polygala; Pyrones; Stigmasterol

2006
[Isolation and structure identification of the chemical constituents from Gypsophila oldhamiana].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:11

    Topics: Caffeic Acids; Caryophyllaceae; Molecular Conformation; Molecular Structure; Plant Roots; Plants, Medicinal; Stigmasterol; Sucrose

2005
[Study on the chemical constituents of Curcuma phaeocaulis].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2006, Volume: 29, Issue:7

    Topics: Curcuma; Curcumin; Molecular Structure; Plants, Medicinal; Rhizome; Sesquiterpenes; Stigmasterol

2006
Preparative isolation and purification of chemical constituents from the root of Adenophora tetraphlla by high-speed counter-current chromatography with evaporative light scattering detection.
    Journal of chromatography. A, 2007, Jan-19, Volume: 1139, Issue:2

    Topics: Campanulaceae; Chromatography, High Pressure Liquid; Countercurrent Distribution; Light; Phytosterols; Plant Roots; Sitosterols; Stigmasterol; Triterpenes

2007
Characterization of lipid rafts from Medicago truncatula root plasma membranes: a proteomic study reveals the presence of a raft-associated redox system.
    Plant physiology, 2007, Volume: 144, Issue:1

    Topics: Cell Fractionation; Medicago truncatula; Membrane Lipids; Membrane Microdomains; Oxidation-Reduction; Plant Proteins; Plant Roots; Proteomics; Solubility; Stigmasterol

2007
[Chemical constituents from root of Psammosilene tunicoides].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:10

    Topics: Caryophyllaceae; Cerebrosides; Isoflavones; Magnetic Resonance Spectroscopy; Plant Roots; Plants, Medicinal; Spectrometry, Mass, Electrospray Ionization; Stigmasterol

2007
[Study on liposoluble constituents of Teucrium labiosum].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2008, Volume: 31, Issue:7

    Topics: Alcohols; Lamiaceae; Magnetic Resonance Spectroscopy; Oleanolic Acid; Pentacyclic Triterpenes; Plants, Medicinal; Solvents; Stearic Acids; Stigmasterol; Triterpenes

2008
Antinociceptive properties of the hydroalcoholic extract, fractions and compounds obtained from the aerial parts of Baccharis illinita DC in mice.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 104, Issue:4

    Topics: Analgesics; Animals; Baccharis; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Mice; Oleanolic Acid; Pain; Pain Measurement; Plant Components, Aerial; Plant Extracts; Receptors, Glutamate; Solvents; Stigmasterol; Triterpenes

2009
Antiproliferative, apoptotic and antimutagenic activity of isolated compounds from Polyalthia cerasoides seeds.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:7

    Topics: Antimutagenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Caco-2 Cells; Cell Proliferation; Chromosome Breakage; Colonic Neoplasms; Diterpenes, Clerodane; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Methyl Methanesulfonate; Mutagens; Mutation; Phytotherapy; Plant Extracts; Polyalthia; Seeds; Stigmasterol

2010
Antiulcerogenic activity of extract, fractions, and some compounds obtained from Polygala cyparissias St. Hillaire & Moquin (Polygalaceae).
    Naunyn-Schmiedeberg's archives of pharmacology, 2010, Volume: 381, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Bethanechol; Dose-Response Relationship, Drug; Ethanol; Hydrochloric Acid; Mice; Phytotherapy; Plant Extracts; Polygalaceae; Stigmasterol; Stomach Ulcer; Xanthones

2010
Anti-inflammatory effect of crude extract and isolated compounds from Baccharis illinita DC in acute skin inflammation.
    Journal of ethnopharmacology, 2010, Jul-20, Volume: 130, Issue:2

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Baccharis; Capsaicin; Dermatitis, Contact; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Ear; Edema; Male; Mice; Neutrophil Infiltration; Oleanolic Acid; Plant Leaves; Plant Preparations; Stigmasterol; Tetradecanoylphorbol Acetate

2010
Antioxidant activity of Heterotheca inuloides extracts and of some of its metabolites.
    Toxicology, 2010, Sep-30, Volume: 276, Issue:1

    Topics: Antioxidants; Asteraceae; Dose-Response Relationship, Drug; Hydrogen Peroxide; Inhibitory Concentration 50; Medicine, Traditional; Mexico; Plant Extracts; Quercetin; Reactive Oxygen Species; Stigmasterol

2010
Cytoprotective and anti-inflammatory effects of spinasterol via the induction of heme oxygenase-1 in murine hippocampal and microglial cell lines.
    International immunopharmacology, 2010, Volume: 10, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Culture Techniques; Cell Line; Cell Survival; Cytoprotection; Dinoprostone; Enzyme Induction; Heme Oxygenase-1; Hippocampus; Interleukin-1; Mice; Microglia; Molecular Structure; Oxidative Stress; Reactive Oxygen Species; Stigmasterol; Tumor Necrosis Factor-alpha

2010
Antiproliferative constituents of the roots of Conyza canadensis.
    Planta medica, 2011, Volume: 77, Issue:11

    Topics: Antineoplastic Agents, Phytogenic; Apigenin; Cell Line, Tumor; Chemical Fractionation; Chromatography, High Pressure Liquid; Conyza; Female; Humans; Hydroxy Acids; Magnetic Resonance Spectroscopy; Molecular Structure; Oils, Volatile; Oleanolic Acid; Oleic Acids; Plant Extracts; Plant Roots; Pyrones; Sitosterols; Stigmasterol

2011
Downregulation of matrix metalloproteinase-13 by the root extract of Cyathula officinalis Kuan and its constituents in IL-1β-treated chondrocytes.
    Planta medica, 2011, Volume: 77, Issue:13

    Topics: Acetates; Alkynes; Amaranthaceae; Animals; Carrageenan; Cartilage; Cell Line, Tumor; Chondrocytes; Chondrosarcoma; Disease Models, Animal; Dopamine; Down-Regulation; Edema; Humans; Hypolipidemic Agents; Interleukin-1beta; Lactones; Male; Matrix Metalloproteinase 13; Medicine, Chinese Traditional; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Plant Roots; Sesquiterpenes; Sitosterols; Stigmasterol

2011
A glycosidic spinasterol from Koreana stewartia promotes procollagen production and inhibits matrix metalloproteinase-1 expression in UVB-irradiated human dermal fibroblasts.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:5

    Topics: Base Sequence; Blotting, Western; Cells, Cultured; DNA Primers; Fibroblasts; Humans; Matrix Metalloproteinase 1; Procollagen; Skin; Spectrometry, Mass, Fast Atom Bombardment; Stigmasterol; Theaceae

2011
[Study on the chemical constituents of Codonopsis lanceolata].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2011, Volume: 34, Issue:4

    Topics: Codonopsis; Glucosides; Magnetic Resonance Spectroscopy; Phenylpropionates; Plant Roots; Plants, Medicinal; Shikimic Acid; Stigmasterol; Triterpenes

2011
Antihyperalgesic activity of the methanol extract and some constituents obtained from Polygala cyparissias (Polygalaceae).
    Basic & clinical pharmacology & toxicology, 2012, Volume: 111, Issue:3

    Topics: Analgesics; Animals; Carrageenan; Disease Models, Animal; Drug Evaluation, Preclinical; Epinephrine; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Lipopolysaccharides; Medicine, Traditional; Methanol; Mice; Neuralgia; Pain; Plant Extracts; Polygala; Sciatic Nerve; Stigmasterol; Xanthones

2012
Inhibitory effects of a spinasterol glycoside on lipopolysaccharide-induced production of nitric oxide and proinflammatory cytokines via down-regulating MAP kinase pathways and NF-κB activation in RAW264.7 macrophage cells.
    International immunopharmacology, 2012, Volume: 13, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Base Sequence; Cell Line; Cytokines; Down-Regulation; Glycosides; I-kappa B Kinase; I-kappa B Proteins; Inflammation Mediators; Lipopolysaccharides; Macrophage Activation; Male; MAP Kinase Signaling System; Medicine, Korean Traditional; Mice; Mice, Inbred C57BL; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; RNA, Messenger; Stigmasterol; Theaceae

2012
Identification of the plant steroid α-spinasterol as a novel transient receptor potential vanilloid 1 antagonist with antinociceptive properties.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 343, Issue:2

    Topics: Analgesics; Animals; Binding, Competitive; Body Temperature; Calcium; Capsaicin; Chromatography, High Pressure Liquid; Diterpenes; Edema; Freund's Adjuvant; Hot Temperature; Male; Mice; Nociceptors; Pain; Pain Measurement; Plant Extracts; Plant Leaves; Stigmasterol; Tissue Distribution; TRPV Cation Channels; Vernonia

2012
[Study on triterpenoids from Wisteria sinensis].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:8

    Topics: Ethanol; Molecular Structure; Plant Stems; Sitosterols; Stigmasterol; Triterpenes; Wisteria

2012
Anti-inflammatory action of hydroalcoholic extract, dichloromethane fraction and steroid α-spinasterol from Polygala sabulosa in LPS-induced peritonitis in mice.
    Journal of ethnopharmacology, 2014, Volume: 151, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Ethanol; Lipopolysaccharides; Methylene Chloride; Mice; Molecular Structure; Peritonitis; Plant Extracts; Polygala; Stigmasterol; Water

2014
Biological activities of Schottenol and Spinasterol, two natural phytosterols present in argan oil and in cactus pear seed oil, on murine miroglial BV2 cells.
    Biochemical and biophysical research communications, 2014, Apr-11, Volume: 446, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Cell Line; Gene Expression Regulation; Lipoproteins; Liver X Receptors; Membrane Potential, Mitochondrial; Mice; Microglia; Opuntia; Orphan Nuclear Receptors; Plant Oils; Seeds; Sitosterols; Sterols; Stigmasterol

2014
α-Spinasterol from Melandrium firmum attenuates benign prostatic hyperplasia in a rat model.
    Molecular medicine reports, 2014, Volume: 9, Issue:6

    Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Male; Organ Size; Plant Extracts; Prostate; Prostatic Hyperplasia; Rats; Stigmasterol; Testosterone

2014
An expeditious synthesis of spinasterol and schottenol, two phytosterols present in argan oil and in cactus pear seed oil, and evaluation of their biological activities on cells of the central nervous system.
    Steroids, 2015, Volume: 99, Issue:Pt B

    Topics: Animals; Cell Line; Cell Proliferation; Central Nervous System; Humans; Mice; Mitochondria; Phytosterols; Plant Oils; Pyrus; Rats; Seeds; Sitosterols; Stigmasterol

2015
α-Spinasterol, a TRPV1 receptor antagonist, elevates the seizure threshold in three acute seizure tests in mice.
    Journal of neural transmission (Vienna, Austria : 1996), 2015, Volume: 122, Issue:9

    Topics: Animals; Anticonvulsants; Body Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Male; Mice; Motor Activity; Muscle Strength; Pentylenetetrazole; Random Allocation; Seizures; Stigmasterol; Treatment Outcome; TRPV Cation Channels

2015
[Study on Chemical Constituents of Kalimeris indica].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:1

    Topics: Asteraceae; Phytochemicals; Stigmasterol

2015
Glanduliferins A and B, two new glucosylated steroids from Impatiens glandulifera, with in vitro growth inhibitory activity in human cancer cells.
    Fitoterapia, 2016, Volume: 109

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Humans; Impatiens; Molecular Structure; Naphthoquinones; Plant Stems; Saponins; Steroids; Stigmasterol

2016
Evaluation of the antidepressant- and anxiolytic-like activity of α-spinasterol, a plant derivative with TRPV1 antagonistic effects, in mice.
    Behavioural brain research, 2016, Apr-15, Volume: 303

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Body Temperature; Capsaicin; Depression; Male; Mice; Motor Activity; Stigmasterol; TRPV Cation Channels

2016
A new compound, methylbergenin along with eight known compounds with cytotoxicity and anti-inflammatory activity from Ardisia japonica.
    Natural product research, 2017, Volume: 31, Issue:22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ardisia; Benzopyrans; Crystallography, X-Ray; Drug Evaluation, Preclinical; Hep G2 Cells; Humans; Lipopolysaccharides; Macrophages; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Nitric Oxide; Stigmasterol; Triterpenes

2017
A novel method for synthesis of α-spinasterol and its antibacterial activities in combination with ceftiofur.
    Fitoterapia, 2017, Volume: 119

    Topics: Anti-Bacterial Agents; Cephalosporins; Drug Synergism; Escherichia coli; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus; Stigmasterol

2017
The Potential of α-Spinasterol to Mimic the Membrane Properties of Natural Cholesterol.
    Molecules (Basel, Switzerland), 2017, Aug-22, Volume: 22, Issue:8

    Topics: Cholesterol; Fluorescence; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membranes, Artificial; Permeability; Phospholipids; Plant Oils; Stigmasterol

2017
α-Spinasterol: a COX inhibitor and a transient receptor potential vanilloid 1 antagonist presents an antinociceptive effect in clinically relevant models of pain in mice.
    British journal of pharmacology, 2017, Volume: 174, Issue:23

    Topics: Acute Pain; Administration, Oral; Analgesics; Animals; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Hyperalgesia; Male; Mice; Neuralgia; Pain, Postoperative; Stigmasterol; Time Factors; TRPV Cation Channels

2017
A new sesquiterpene from Kalimeris integrifolia.
    Natural product research, 2018, Volume: 32, Issue:9

    Topics: Alkynes; Antineoplastic Agents, Phytogenic; Asteraceae; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Furaldehyde; Furans; Glucosides; Humans; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Sesquiterpenes; Stigmasterol; Triterpenes

2018
The molecular basis of cytotoxicity of α-spinasterol from Ganoderma resinaceum: Induction of apoptosis and overexpression of p53 in breast and ovarian cancer cell lines.
    Journal of cellular biochemistry, 2018, Volume: 119, Issue:5

    Topics: Apoptosis; Breast Neoplasms; Female; Ganoderma; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Ovarian Neoplasms; Stigmasterol; Tumor Suppressor Protein p53

2018
Sodium metavanadate induced cognitive decline, behavioral impairments, oxidative stress and down regulation of myelin basic protein in mice hippocampus: Ameliorative roles of β-spinasterol, and stigmasterol.
    Brain and behavior, 2018, Volume: 8, Issue:7

    Topics: Animals; Antioxidants; Behavior, Animal; Cognitive Dysfunction; Down-Regulation; Hippocampus; Lipid Peroxidation; Male; Memory Disorders; Mice; Mice, Inbred BALB C; Myelin Basic Protein; Neurotoxicity Syndromes; Oxidative Stress; Stigmasterol; Vanadates

2018
Antityrosinase, Antioxidant, and Cytotoxic Activities of Phytochemical Constituents from
    Molecules (Basel, Switzerland), 2019, Jul-31, Volume: 24, Issue:15

    Topics: Antioxidants; Arbutin; Cell Line, Tumor; Cell Proliferation; Flavonoids; Humans; Hydroxybenzoates; Manilkara; Monophenol Monooxygenase; Neoplasms; Oleanolic Acid; Phytochemicals; Pyrones; Stigmasterol

2019
Antioxidant, antifungal, and aphicidal activity of the triterpenoids spinasterol and 22,23-dihydrospinasterol from leaves of Citrullus colocynthis L.
    Scientific reports, 2022, 03-22, Volume: 12, Issue:1

    Topics: Antifungal Agents; Antioxidants; Citrullus colocynthis; Plant Leaves; Sitosterols; Stigmasterol; Triterpenes

2022