spermine has been researched along with spermidine in 2534 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1249 (49.29) | 18.7374 |
| 1990's | 569 (22.45) | 18.2507 |
| 2000's | 355 (14.01) | 29.6817 |
| 2010's | 237 (9.35) | 24.3611 |
| 2020's | 124 (4.89) | 2.80 |
| Authors | Studies |
|---|---|
| Coward, JK; Lakanen, JR; Pegg, AE | 1 |
| Edwards, ML; Snyder, RD; Stemerick, DM | 1 |
| Jan, LY; Jan, YN; Yang, J | 1 |
| Lopatin, AN; Makhina, EN; Nichols, CG | 2 |
| Frølund, B; Jaroszewski, JW; Krogsgaard-Larsen, P; Matzen, L | 1 |
| Arndt, P; Busch, AE; Gorboulev, V; Koepsell, H; Lang, F; Quester, S; Ulzheimer, JC; Waldegger, S | 1 |
| Adams, DM; Barth, RF; Cai, J; Hariharan, JR; Radcliffe, K; Soloway, AH; Wyzlic, IM | 1 |
| Adams, DM; Barth, RF; Cai, J; Ji, W; Soloway, AH; Tjarks, W; Zhuo, JC | 1 |
| Nezu, J; Oku, A; Sai, Y; Sakamoto, K; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H | 1 |
| Eboshi, R; Hamachi, I; Hiraoka, T; Shinkai, S; Yamada, Y | 1 |
| Audette, M; Bonneau, MJ; Charest-Gaudreault, R; Covassin, L; Desjardins, M; Poulin, R | 1 |
| Burns, MR; Cai, F; Carlson, CL; Graminski, GF; Vanderwerf, SM; Webb, HK; Weeks, RS; Ziemer, JR | 1 |
| Burns, MR; Cai, F; Carlson, CL; Graminski, GF; Vanderwerf, SM; Vermeulen, NM; Ziemer, JR | 1 |
| Biggerstaff, J; Delcros, JG; Phanstiel, O; Wang, C | 1 |
| Audette, M; Charest-Gaudreault, R; Covassin, L; Desjardins, M; Poulin, R; Soulet, D | 1 |
| Delcros, JG; Duhieu, S; Eifler-Lima, V; Foucault, M; Le Roch, M; Martin, B; Renault, J; Tomasi, S; Uriac, P | 1 |
| Kwon, DH; Lu, CD | 1 |
| Bazin, MA; Boustie, J; Corbel, JC; Delcros, JG; Le Lamer, AC; Rouaud, I; Tomasi, S; Uriac, P | 1 |
| de Medina, P; Paillasse, MR; Payré, B; Poirot, M; Silvente-Poirot, S | 1 |
| Carta, F; Innocenti, A; Kaila, K; Scozzafava, A; Supuran, CT; Temperini, C | 1 |
| Athanassopoulos, CM; Bariamis, SE; Grafanaki, K; Hadjipavlou-Litina, D; Magoulas, GE; Maroulis, G; Papaioannou, D; Pontiki, E; Tsegenidis, T | 1 |
| Gruber, JD; Pachaiyappan, B; Schmidt, MG; Wang, B; Woster, PM; Zhang, YM | 1 |
| Byl, JAW; De Vivo, M; Minarini, A; Minniti, E; Osheroff, N; Riccardi, L; Rosini, M; Sissi, C | 1 |
| Hsu, CH; Pickett, EE; Sehgal, OP | 1 |
| Chun, PW; Rennert, OM; Saffen, EE; Taylor, WJ | 1 |
| Frank, JJ; Levy, CC | 1 |
| Haygarth, WL; Smith, TA; Williams, JF | 1 |
| Hölttä, E | 1 |
| Jänne, J; Kallio, A; Pösö, H; Scalabrino, G | 1 |
| Taylor, JM; Tse, TP | 1 |
| Hirose, S; Igarashi, K; Kumagai, H; Oguchi, H | 1 |
| Conroy, PD; Pointon, JJ; Simms, DM | 1 |
| Kleppe, K; Osland, A | 2 |
| Aoki, Y; Hirose, S; Igarashi, K | 1 |
| Galaev, IuV; Siatkin, SP | 1 |
| Shaw, GG | 4 |
| Baldwin, RL; Christiansen, C | 1 |
| Chvapil, M; Chvapil, T; Eskelson, C | 1 |
| Hirose, S; Igarashi, K; Kitada, M; Kitagawa, H | 1 |
| Gahl, WA; Pitot, HC | 2 |
| Kessler, GF; Lipton, A; Sheehan, LM | 1 |
| Russell, DH; Russell, SD | 1 |
| Aupoix, M; Greenland, T; Niveleau, A; Quash, GA | 1 |
| Gasior, E; Jakubowicz, T; Wolska-Mitaszko, B | 1 |
| Links, J; Svec, J | 1 |
| Eisner, RA; Ingoglia, NA; Sturman, JA | 1 |
| Dunzendorfer, U; Russell, DH | 3 |
| Nishioka, K; Romsdahl, MM; Takami, H | 1 |
| Savory, J; Shipe, JR; Wills, MR | 2 |
| Cohen, SS; Guarino, L; Ramakrishna, S | 1 |
| Datta, AK; Suryanarayana, T | 1 |
| Aleksijevic, A; Grove, J; Schuber, F | 1 |
| Hori, C; Kano, K; Oka, T; Sakai, T | 1 |
| Caldarera, CM; Casti, A; Guarnieri, C; Moruzzi, G | 1 |
| Matsushita, S | 1 |
| Amoss, MS; Byrd, WJ; Jacobs, DM | 1 |
| Ahlers, J; Heinrich-Hirsch, B; Peter, HW | 1 |
| Deters, J; McDougall, KJ; Miskimen, J | 1 |
| Oriol-Audit, C | 3 |
| Di Giusto, L; Garcia-Giralt, E; Lenfant, M | 1 |
| Adlakha, RC; di Giusto, L; Garcia-Giralt, E; Lenfant, M; Mayadoux, E; Oleson, DL; Villanueva, V | 1 |
| Foa, P; Jänne, J; Jones, WA; Paile, W; Rytömaa, T; Yuen, TL | 1 |
| Bachner, L; Bogdanovsky, D; Kneip, B; Raymondjean, M; Shapira, G | 1 |
| Bachrach, U; Don, S; Wiener, H | 4 |
| Kleppe, K; Lillehaug, JR | 1 |
| Beard, P; Berg, P; DePamphilis, ML | 1 |
| Russell, DH; Stambrook, PJ | 1 |
| Anderson, CW; Atkins, JF; Gesteland, RF; Lewis, JB | 1 |
| McCormick, FP; Newton, AA | 1 |
| Jänne, J; Raina, A | 1 |
| Müller, WE; Zahn, RK | 1 |
| Hasegawa, M; Tashima, Y | 1 |
| Bachrach, U; Don, S | 1 |
| Mori, M; Tatibana, M | 1 |
| Kleppe, K; Kleppe, RK; Raae, AJ | 1 |
| Inoue, M; Kishimoto, A; Nakaya, S; Nishiyama, K; Nishizuka, Y; Takai, Y; Yamamura, H | 1 |
| Dattilo, JW; Hopkins, HA; Kovacs, CJ; Looney, WB; Morris, HP; Russell, DH | 1 |
| Katsuta, H; Nagai, Y; Nose, K; Takaoka, T | 1 |
| Canellakis, ZN; Theoharides, TC | 1 |
| Cohen, SS; Sakai, TT | 1 |
| Chang, AC; Ferro, AM; Kun, E; Nitecki, D; Sharma, ML | 1 |
| Froscio, M; Murray, AW; Rogers, A | 1 |
| Kacew, S; Merali, Z; Singhal, RL | 1 |
| Fukuyama, H; Yamashita, S | 1 |
| Goldstein, DA; Heby, O; Marton, LJ | 1 |
| Linebaugh, BE; Mulder, JA; Rillema, JA | 1 |
| Glinsmann, W; Nakai, C | 3 |
| Byus, CV; Russell, DH | 1 |
| Voorhees, JJ | 1 |
| Mamont, PS; McCann, PP; Tardif, C | 1 |
| Kawamura, M; Shimoyama, M; Tanigawa, Y | 1 |
| Egberts, E; Hackett, PB; Traub, P | 1 |
| Mäenpää, PH | 1 |
| Perin, A; Sessa, A | 3 |
| Kisara, K; Sakurada, T | 1 |
| Höltje, JV | 1 |
| Aylward, JH; Killilea, SD; Lee, EY; Mellgren, RL | 1 |
| Bachrach, U; Hochman, J; Katz, A | 1 |
| Ahmed, K; Foster, D; Quarfoth, G | 1 |
| Francke, B | 1 |
| McCormick, F | 2 |
| Scamans, E; Tyms, AS; Williamson, JD | 1 |
| Cornatzer, WE; Johnson, WT; Nordlie, RC; Twedell, GW | 1 |
| Kincaid, RL; Manganiello, VC; Vaughan, M | 1 |
| Clough, W | 1 |
| Harik, SI; Sutton, CH | 1 |
| Dunn, AJ; Iuvone, PM; Rennert, OM; Shukla, JB; Tintner, R | 1 |
| Devor, WN; Levin, VA; Marton, LJ; Seidenfeld, J | 1 |
| Jewett, PB; Levy, CC; Schmukler, M | 1 |
| Frank, JJ; Hawk, IA; Levy, CC | 2 |
| Elfving, K; Hölttä, E; Jänne, J; Pulkkinen, P | 1 |
| Eguchi, K; Hirose, S; Igarashi, K; Tanaka, M | 1 |
| Hamana, K; Itoh, K; Matsuzaki, S; Suzuki, M | 1 |
| Arine, RM; Chaffee, RR; Rochelle, RH; Walker, CD | 1 |
| Frias, JL; Lawson, DL; Miale, TD; Rennert, OM; Shukla, JB | 1 |
| Aigner-Held, R; Campbell, RA; Daves, GD | 1 |
| Allen, JC; Gaugas, JM; Hussain, JI; Smith, CJ; Thomas, JM | 1 |
| Russell, DH | 5 |
| Hirose, S; Igarashi, K; Kumagai, H; Yoshikawa, M | 1 |
| McKinnon, IM; Stevens, L; Winther, M | 1 |
| Seiler, N | 4 |
| Wolska-Mitaszko, B | 1 |
| Terabayashi, T | 1 |
| Ahmann, DL; Gehrke, CW; Oliverio, VT; Tormey, DC; Waalkes, TP; Woo, KB | 1 |
| Cohn, MS; Tabor, CW; Tabor, H | 2 |
| Morris, DR; Whitney, PA | 1 |
| Cohn, MS; Tabor, CW; Tabor, H; Wickner, RB | 1 |
| Pavel, P; Schwippelová, Z | 1 |
| Mita, M; Yasumasu, I | 2 |
| Ebert, F; Walter, RD | 1 |
| Goyns, MH | 3 |
| Aoki, R; Hirose, S; Igarashi, K; Kashiwagi, K; Kojima, M | 1 |
| Stevens, L; Winther, MD | 1 |
| Hirose, S; Igarashi, K; Ishizaki, N; Kumagai, H; Watanabe, Y | 1 |
| Dauth, GW; Defendini, R; Gilman, S; Kremzner, LT; Tennyson, VM | 1 |
| Jamdar, SC | 1 |
| Henningsson, S; Persson, L; Rosengren, E | 2 |
| Cox, R | 1 |
| Bey, P; Danzin, C; Grove, J; Jung, MJ | 1 |
| Marton, LJ; Seidenfeld, J | 2 |
| Gies, A; Neumeier, M; Peter, HW; Schädler, R; Wegener, I | 1 |
| Nishioka, K; Pargac, MB; Rao, PN; Sunkara, PS | 1 |
| Ivanov, VI; Kritzyn, AM; Minchenkova, LE; Minyat, EE; Schyolkina, AK | 1 |
| Bloomfield, VA; Wilson, RW | 1 |
| Funkhouser, W; Perini, F; Sadow, J; Sullivan, C; Woo, KB | 1 |
| Maeda, T; Oshima, T; Sakaki, Y | 1 |
| Buchanan, TM; Chen, KC; Forsyth, PS; Holmes, KK | 1 |
| Harsing, L; Posch, E; Selmeci, L; Simon, G | 1 |
| Aramaki, Y; Hayashi, S; Kameji, T; Noguchi, T | 1 |
| Hardesty, B; Kramer, G; Odom, OW | 1 |
| D'Anna, M | 1 |
| Billett, MA; Hall, TJ | 1 |
| Farber, EM; Orenberg, EK; Proctor, MS; Wilkinson, DI | 1 |
| Sakakibara, S; Yoshikawa, K | 1 |
| Knödgen, B; Seiler, N | 1 |
| Cohen, SS; Lapi, L; Torget, R | 1 |
| Hunt, DF; Savory, J; Shipe, JR | 1 |
| Canellakis, ZN; Williams-Ashman, HG | 2 |
| Keir, HM; Melvin, MA; Wallace, HM | 2 |
| Keir, HM; Melvin, MA | 4 |
| Goertz, B | 1 |
| Chan, WY; Rennert, OM; Seale, TW; Shukla, JB | 1 |
| Boxer, LM; Korn, D | 1 |
| Alhonen-Hongisto, L; Jänne, J; Pösö, H | 1 |
| Bylinkina, VS; Leviant, MI; Orekhovich, VN | 1 |
| Bachrach, U; Ben Joseph, M; Greenblatt, CL; Schnur, LF | 1 |
| Bain, R; Blackston, RD; Chawla, RK; Goldsmith, MA; Kutner, MH; Rudman, D | 1 |
| Barnett, DR; Beckerman, RC; Durie, BG; Rosenblum, MG; Russell, DH; Taussig, LM | 1 |
| Das, R; Kanungo, MS | 1 |
| Blau, K; Lax, PM; Rattenbury, JM; Sandler, M | 1 |
| Bachrach, U; Brem, S; Greenblatt, CL; Schnur, LF; Wertman, SB | 1 |
| Al-Therib, MJ; Erdmann, G; Fischer, HA; Seiler, N | 1 |
| Clò, C; Davalli, P; Fanelli, O; Fussi, F; Guarnieri, C | 1 |
| Stone, PR; Whish, WJ; Whitby, AJ | 1 |
| Jerzmanowski, A; Staroń, K; Toczko, K; Tyniec-Kroenke, B | 1 |
| Chambaz, EM; Cochet, C; Job, D; Pirollet, F | 1 |
| Slaga, TJ; Weeks, CE | 1 |
| Alhonen-Hongisto, L; Jänne, J; Kallio, A; Pösö, H | 1 |
| Alexandre, H | 1 |
| Bacchi, CJ; Garofalo, J; Hutner, SH; Lipschik, GY; Vergara, C | 1 |
| Haraguchi, K; Kai, M; Ogata, T; Ohkura, Y | 1 |
| Kleinman, HK; Mosher, DF; Schad, PE | 1 |
| Callahan, M; McComish, MF; Taylor, RF; Yesair, DW | 1 |
| Abbruzzese, A; D'Angelo, L; Della Pietra, G; Motta, G; Rogliani, E | 1 |
| Lundgren, DW; Oka, T; Sakai, T | 1 |
| Brinkley, BR; Nishioka, K; Rao, PN; Sunkara, PS | 1 |
| Rizzo, PJ | 1 |
| Emanuelsson, H; Heby, O | 1 |
| Jänne, J; Koso, P; Piik, K; Pulkkinen, P | 1 |
| McMurtrey, MJ; Nishioka, K; Romsdahl, MM | 1 |
| Canellakis, ES; Fong, WF; Heller, JS; Kyriakidis, D | 1 |
| Brosnan, ME; Symonds, GW | 1 |
| Caldarera, CM; Clô, C; Guarnieri, C; Tantini, B | 1 |
| Cooper, KD; Rennert, OM; Shukla, JB | 2 |
| Sikorska, M; Walker, PR; Whitfield, JF | 1 |
| Paul, D; Rupniak, HT | 1 |
| Hayashi, T; Kawai, S; Ohno, T; Sugiura, T | 1 |
| Andersson, G; Heby, O | 3 |
| Nakjima, T; Sobue, K | 1 |
| Shugaleĭ, VS; Tsvetnenko, EZ | 1 |
| Nakajima, T; Noto, T; Tanaka, T | 1 |
| Cabrini, L; Landi, L; Lenaz, G; Pasquali, P; Sechi, AM | 1 |
| Goodman, RM; Gottlieb, D; Ricciardi, RP | 1 |
| Andersson, G; Heby, O; Osterberg, S | 1 |
| Caldarera, CM; Casti, A; Reali, N; Visioli, O | 1 |
| Saeki, Y; Shirakawa, S; Uehara, N | 1 |
| Anthes, ML; Paretsky, D | 1 |
| Halliday, CA; Shaw, GG | 2 |
| Abbruzzese, A; Della Pietra, G; Porta, R; Servillo, L | 1 |
| Bey, P; Duchesne, MC; Grove, J; Mamont, PS | 1 |
| Kekoni, J; Pajula, RL; Raina, A | 1 |
| Bronson, DL; Elliott, AY; Fraley, EE; Gehrke, CW; Kuo, K; Williams, RD | 1 |
| Augustyniak, J; de Varebeke, PJ; Labuda, D | 1 |
| Lea, MA; Perrella, FW | 1 |
| Hirose, S; Igarashi, K; Kusaka, Y; Nakamura, K; Torii, K | 1 |
| Brosnan, ME; Hall, DE; Symonds, DL; Symonds, GW | 1 |
| Kotake, T; Matsuda, M; Nakajima, T; Osafune, M; Sobue, K; Sonoda, T | 1 |
| Canellakis, ES; Chen, KY; Fong, WF; Heller, JS; Kyriakidis, DA | 1 |
| Keir, HM; Melvin, MA; Melvin, WT | 1 |
| Buehler, BA; Rennert, OM; Schott, SN; Wright, RK | 1 |
| Farwell, DC; Herbst, EJ; Nolan, CE | 1 |
| Byrne, RH; Kidwell, WR; Stone, PR | 1 |
| Harris, JW; Kehe, CR | 1 |
| Anderson, TF; Combest, WL; Duell, EA; Russell, DH; Stawiski, MA; Voorhees, JJ | 1 |
| Calatroni, A; Macaione, S | 1 |
| Cartenì-Farina, M; De Rosa, M; Gambacorta, A; Porta, R; Zappia, V | 1 |
| Rosso, P; Rozovski, SJ; Winick, M | 1 |
| Endo, Y | 1 |
| Knutson, JC; Morris, DR | 1 |
| Atmar, VJ; Daniels, GR; Kuehn, GD | 2 |
| Campbell, JL; Christian, CD; Giles, HR; Russell, DH | 1 |
| Ben-Hur, E; Prager, A; Riklis, E | 1 |
| Ben-Hur, E; Riklis, E | 1 |
| Asada, A; Inoue, H; Kato, Y; Takeda, Y | 1 |
| Caldarera, CM; Casti, A; Corti, A; Drusiani, F; Orlandini, G | 1 |
| Bellia, V; Nardo, F; Panella, M; Piazza, G; Pinturo, R; Rapisarda, A; Savoca, S; Vanella, A; Vasta, M | 1 |
| Eloranta, TO; Raina, AM | 1 |
| Schmidt, GJ; Slavin, W; Vandemark, FL | 1 |
| Carter, DD; Mitchell, JL; Rybski, JA | 1 |
| Gohda, E; Inoue, H; Kato, Y; Nishihara, H; Takeda, Y | 1 |
| Andersson, AC; Henningsson, S; Rosengren, E | 1 |
| Guha, SK; Hölttä, E; Jänne, J | 1 |
| Tabor, CW; Tabor, H | 4 |
| Ogiso, Y; Ohnishi, T; Takeda, Y | 1 |
| Deutscher, MP; Evans, JA | 1 |
| Tormey, DC; Waalkes, TP | 1 |
| Stevens, L; Winther, M | 1 |
| Hope, JA; Stevens, L | 1 |
| Kallistratos, G | 1 |
| Gaull, GE; Sturman, JA | 2 |
| Matsuzaki, S; Suzuki, M | 2 |
| Bamberg, E; Desser, H; Weiser, M | 1 |
| Chow, CT | 1 |
| Byus, CV; Herbst, EJ | 1 |
| Guha, SK; Jänne, J | 1 |
| Frank, JJ; Levy, CC; Neuwelt, EA | 1 |
| Durie, BG; Russell, DH; Salmon, SE | 1 |
| Douglas, CJ; Irving, CC; Roszell, JA | 1 |
| Rosenblum, MG; Russell, DH | 1 |
| Asberry, BE; Coleman, RE; Fair, WR; Primeau, JL; Straatmann, MG; Ter-Pogossian, MM; Welch, MJ | 1 |
| Gerner, EW; Russell, DH | 1 |
| Gurny, PA; Livingston, JN; Lockwood, DH | 1 |
| Elliott, RM; Kelly, DC | 1 |
| Abdel-Monem, MM; Newton, NE | 1 |
| Spaulding, SW | 1 |
| Eriksen, A; Krokan, H | 1 |
| Gray, RW; Guggisberg, A; Hesse, M | 1 |
| Adler, H; Margoshes, M; Snyder, LR; Spitzer, C | 1 |
| Blankenship, J; Walle, T | 1 |
| Nishioka, K; Rao, PN; Sunkara, PS | 2 |
| McAnulty, PA; Williams, JP | 1 |
| Donaldson, LJ; Fuller, DJ; Takyi, EE; Thomas, GH | 1 |
| Bardin, CW; Demers, LM; Feil, PD; Pegg, AE | 1 |
| Konishi, H; Nakajima, T; Sano, I | 1 |
| Lawson, DL; Miale, TD; Rennert, OM; Shukla, JB | 1 |
| Shaskan, EG | 1 |
| Max, ST; Oh, TH | 1 |
| Bartos, D; Bartos, F; Campbell, RA; Grettie, DP | 2 |
| Farrell, PJ; Hunt, T; Hunter, AR; Jackson, RJ | 1 |
| Bachner, L; Bogdanovsky, D; Kneip, B; Raymondjean, M; Schapira, G | 1 |
| Enagonio, RD; Woo, KB | 1 |
| Dickerson, JW; Hey, EN; McAnulty, PA; Waterlow, JC; Yusuf, HK | 1 |
| Argento-Cerù, MP; Beninati, S; Sartori, C | 1 |
| Karpetsky, TP; Levy, CC | 2 |
| Jorstad, CM; Morris, DR; Seyfried, CE | 1 |
| Bacchi, CJ; Lipschik, GY; Nathan, HC | 1 |
| Daves, GD; Smith, RG | 1 |
| Duffy, PE; Kremzner, LT | 1 |
| Arine, RM; Chaffee, RR; Rochelle, RH; Salganicoff, L; Schultz, EL | 1 |
| Camardella, M; Della Pietra, G; Esposito, C; Porta, R | 1 |
| Parrish, RF; Polakoski, KL | 1 |
| Asada, A; Gohda, E; Inoue, H; Mori, Y; Takeda, Y; Takigawa, M | 1 |
| Wedgwood, MA; Wolstencroft, JH | 1 |
| Diamond, L; O'Brien, TG | 1 |
| Fuller, DJ; Gerner, EW; Russell, DH | 1 |
| Nishioka, K; Romsdahl, MM | 2 |
| Gray, JW; Heby, O; Marton, LJ; Wilson, CB | 1 |
| Kisara, K; Kohno, H; Sakurada, T; Tadano, T | 1 |
| Buetti, E; Choppin, PW | 1 |
| Changus, JE; Gahl, WA; Pitot, HC | 1 |
| Imahori, K; Ohno-Iwashita, Y; Oshima, T | 1 |
| Atmar, VJ; Garcia, G; Kuehn, GD; Westland, JA | 1 |
| Guadagnini, P; Masotti, L; Sechi, AM; Spisni, A | 1 |
| Masotti, L; Sechi, AM; Spisni, A | 1 |
| Ho, H; Morley, CG | 1 |
| Cohen, LF; Farrell, PM; Lundgren, DW | 1 |
| Harvey, HA; Lipton, A; Mortel, R; Sheehan, L | 1 |
| Bates, RR; Edwards, WD; Yuspa, SH | 1 |
| Ando, T; Masaki, S; Yoshida, S | 1 |
| Buehler, B; Lawson, D; Miale, T; Rennert, O | 1 |
| Ingoglia, NA; Lindquist, TD; Sturman, JA | 1 |
| Jacob, ST; Rose, KM | 1 |
| Manen, CA; Russell, DH; Schmidt-Nielsen, B | 1 |
| Glanville, N; Ulmanen, I | 1 |
| Abdel-monem, MM; Newton, NE; Ohno, K | 1 |
| Anand, R; Gore, MG; Kerkut, GA | 1 |
| Balis, ME; Ball, WJ | 1 |
| Barboso, G; Caldarera, CM; Casti, A; Guarnieri, C; Reali, N; Rolli, A | 1 |
| Burma, DP; Ghosh, S | 1 |
| Boynton, AL; Isaacs, RJ; Whitfield, JF | 1 |
| Lee, KJ; Masuda, K; Yamada, T | 1 |
| Jänne, J; Pösö, H | 1 |
| Blake, RL; Manen, CA; Russell, DH | 1 |
| Henningsson, S; Rosengren, E | 2 |
| Banda, PW; Marton, LJ; Townsend, RM | 1 |
| Bulger, WH; Kupfer, D | 1 |
| Pegg, AE; Rannels, DE; Rannels, SR | 1 |
| Hildrum, KI; Libbey, LM; Scanlan, RA | 1 |
| Imai, M; Kisara, K; Sakurada, T; Tadano, T | 1 |
| Nakano, T; Tsuboi, M | 1 |
| Gohda, E; Inoue, H; Kato, Y; Takeda, Y; Tamada, F | 1 |
| Atkinson, M; Johnson, DE; McGregor, RF; Sharon, MS | 1 |
| Tanimura, K; Terabayashi, T; Ueki, K | 1 |
| Fillingame, RH; Jorstad, CM; Morris, DR | 1 |
| Bey, P; Böhlen, P; Mamont, PS; McCann, PP; Schuber, F; Tardif, C | 1 |
| Zakrevskiĭ, VI | 1 |
| Oka, T | 1 |
| Onishi, T; Takeda, Y | 1 |
| Barbiroli, B; Moruzzi, G; Moruzzi, MS; Tadolini, B | 1 |
| Burma, DP; Suryanarayana, T | 1 |
| Schimmel, PR; Schreier, AA | 1 |
| Cohen, SS; Fukuma, I | 1 |
| Cohen, SS; Freda, CE; I, J; Sakai, TT; Torget, R | 1 |
| Lamberty, U; Seiler, N | 3 |
| Nakajima, T; Sano, I; Tsuji, M | 1 |
| Schmidt-Glenewinkel, T; Seiler, N | 1 |
| Munshi, SR; Purandare, TV; Rao, SS; Sheth, AR; Thakur, AN | 1 |
| Brade, WP; Fleischer-Lambropoulos, H; Sarkander, HI | 1 |
| Comolli, R; Ferioli, ME | 1 |
| Brorsson, U; Fair, WR; Wehner, N | 1 |
| Di Sant'Agnese, PA; Farrell, PM; Lundgren, DW | 1 |
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| Azfar, M; Coene, J; Daniëls, V; Eggermont, J; Houdou, M; Jacobs, N; Van den Haute, C; Vangheluwe, P; Vanhoutte, R; Verhelst, SHL | 1 |
| Chen, L; Gao, C; Liao, X; Yang, B; Yang, J; Zhang, S; Zhou, C | 1 |
| Čelić, TV; Kebert, M; Kojić, D; Pihler, I; Purać, J; Vukašinović, EL; Đorđievski, S | 1 |
| Ahn, S; An, YB; Baik, JY; Choi, H; Hong, JK; Hong, M; Kang, DE; Kim, Y; Kim, YJ; Lee, DY; Lee, GM; Lim, JS; Park, J; Ryu, SH; Yoo, J; You, WK | 1 |
| Chen, BX; Kurtenbach, R; Li, YB; Liu, HP | 1 |
| Acuña, SM; de Almeida Bento, C; de Souza Angelo, Y; Muxel, SM; Peron, JPS; Stolf, BS; Zanatta, JM | 1 |
| Čapelja, E; Flors, V; Kebert, M; Kesić, L; Kostić, S; Markić, AG; Stojnić, S; Zorić, M | 1 |
| Grimm, M; Kordowski, A; Otzen, H; Schick, P; Schmelter, F; Senekowitsch, S; Sina, C; Smollich, M; Weitschies, W; Wietkamp, E | 1 |
| Aigner, F; Ashraf, MI; Boivin, FJ; Breiderhoff, T; Fähling, M; Hartner, A; Kelterborn, S; Kirschner, KM; Knauf, F; Lichtenberger, FB; Ögel, N; Reichel, M; Rosenberger, C; Schley, G; Schmidt-Ott, K; Scholz, H; Sieckmann, T; Vigolo, E | 1 |
| Aksoy, A; Alkan, A; Atmaca, E; Das, YK | 1 |
| Banda, G; Barreiro-Alonso, E; Cantabrana, B; Rodríguez-Uña, I; Rubín, JM; Sánchez, M; Suárez, L | 1 |
| Bronson, AS; Lilley, CM; Mirza, KM; Zleczewski, M | 1 |
| Chizhov, AO; Gottikh, MB; Khomutov, AR; Khomutov, MA; Kochetkov, SN; Korolev, SP; Mitkevich, VA; Salikhov, AI; Smirnova, OA; Tunitskaya, VL | 1 |
| Cappella, A; Castelli, L; Ciorciari, A; Galasso, L; Montaruli, A; Mulè, A; Stacchiotti, A | 1 |
| Almeida-Hernández, Y; Bekaddour, N; Benichou, S; Boonen, A; Caspar, B; Cathelin, D; Groß, R; Han, M; Harms, M; Herbeuval, JP; Klein, F; Kleipass, F; Lagane, B; Münch, J; Rodriguez-Alfonso, A; Ruiz-Blanco, YB; Sanchez-Garcia, E; Sayettat, S; Schols, D; Smith, N; Ständker, L; Stürzel, C; Tahar, B; Vanshylla, K; von Maltitz, P; Wiese, S | 1 |
| Bazer, FW; Halloran, KM; He, W; Moses, RM; Newton, MG; Sah, N; Stenhouse, C; Wu, G | 1 |
| Forwood, JK; Khandokar, YB; Kuhn, ML; Le, VTB; Shornikov, A; Srivastava, P; Tsimbalyuk, S; Warren, I | 1 |
| Bernard, R; Eaton, MJ; Laube, G; Rieck, J; Skatchkov, SN; Veh, RW; Weiss, T | 1 |
| González-Vega, JC; Htoo, JK; Kluenemann, M; Lee, J; Nyachoti, CM | 1 |
| An, X; Guo, Y; Ji, C; Jiang, D; Kang, B; Kang, L; Ling, W; Niu, C; Sun, Q; Wang, X; Wang, Z | 1 |
| Chen, Z; Han, H; He, Y; Meng, J; Su, N; Zhao, Q | 1 |
| Furuchi, T; Matsunaga, M; Takao, K; Uemura, T; Yokota, Y | 1 |
| Casero, RA; Foley, JR; Holbert, CE; Khomutov, AR; Khomutov, M; Rastkari, N; Stewart, TM; Tao, X; Zhai, RG | 1 |
| Barvkar, VT; Dhondge, HV; Nadaf, AB; Singh, SK; Zehra, A | 1 |
| Aguirre-Alvarado, C; Chamorro-Cevallos, G; Cordero-Martínez, J; García-Pérez, CA; Hugo, CP; Jiménez-Gutiérrez, GE; Rodríguez-Páez, L; Sandra Irel, CE; Veronica, AF | 1 |
| Agathokleous, E; Calabrese, E; Calabrese, V; Dhawan, G; Hayes, AW; Kapoor, R; Pressman, P | 1 |
| Aboutalebi-Jahromi, AH; Jalali, P; Sadeghi, H; Zakerin, AR | 1 |
| Rašková, M; Šebela, M | 1 |
| He, L; Kang, W; Shi, S; Wang, W | 1 |
| Borbolla Jiménez, FV; Cordero-Martínez, J; Cristóbal-Luna, JM; Jimenez Gutierrez, GE; Leyva Garcia, N; Magaña, JJ; Muñoz, LG; Murillo Melo, NM; Tapia Guerrero, YS | 1 |
110 review(s) available for spermine and spermidine
| Article | Year |
|---|---|
Physiology of the natural polyamines putrescine, spermidine and spermine.
Topics: Adrenocorticotropic Hormone; Animals; Chickens; DNA; Estradiol; Estrogens; Glucocorticoids; Gonadotropins; Growth Hormone; Male; Progesterone; Putrescine; Rats; RNA; Spermidine; Spermine | 1975 |
Effects of polyamines on the structure and reactivity of tRNA.
Topics: Binding Sites; Chloromercuribenzoates; Cyanogen Bromide; Electron Spin Resonance Spectroscopy; Ethidium; Iodoacetamide; Kinetics; Magnesium; Nucleic Acid Conformation; Polyamines; Putrescine; RNA, Transfer; Spermidine; Spermine; Thiouridine; X-Ray Diffraction | 1976 |
Ornithine decarboxylase: transsynaptic induction in the adrenal medulla.
Topics: Adrenal Medulla; Aminophylline; Animals; Carbachol; Carboxy-Lyases; Cold Temperature; Cyclic AMP; Enzyme Induction; Kinetics; Mecamylamine; Ornithine Decarboxylase; Protein Kinases; Putrescine; Reserpine; Spermidine; Spermine; Synapses | 1976 |
Pathophysiology of psoriasis.
Topics: Cell Membrane; Cyclic AMP; Cyclic GMP; HLA Antigens; Humans; Nucleotides, Cyclic; Polyamines; Prostaglandins; Prostaglandins E; Prostaglandins F; Psoriasis; Skin; Spermidine; Spermine | 1977 |
Clinical relevance of polyamines as biochemical markers of tumor kinetics.
Topics: Animals; Humans; Kinetics; Neoplasms; Neoplasms, Experimental; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1977 |
Assay procedures for polyamines in urine, serum, and cerebrospinal fluid.
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Thin Layer; Dansyl Compounds; Humans; Microchemistry; Polyamines; Putrescine; Radioimmunoassay; Spermidine; Spermine | 1977 |
A quantitative approach to determining disease response during therapy using multiple biologic markers: application to carcinoma of the breast.
Topics: Breast Neoplasms; Carcinoembryonic Antigen; Female; Guanosine; Humans; Inosine; Nucleosides; Polyamines; Pseudouridine; Putrescine; Regression Analysis; Spermidine; Spermine; Time Factors | 1978 |
[Polyamines and malignant melanoma (author's transl)].
Topics: Animals; Humans; Mammals; Melanoma; Polyamines; Putrescine; Skin Neoplasms; Spermidine; Spermine | 1979 |
Spermine, spermidine and putrescine in fungal development.
Topics: Arginine; Fungi; Methionine; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine; Spores, Fungal | 1979 |
Polyamines in mammalian liver during growth and development.
Topics: Animals; Chick Embryo; Hormones; Humans; Liver; Liver Neoplasms; Liver Regeneration; Mammals; Ornithine; Pharmacology; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1976 |
1,4-Diaminobutane (putrescine), spermidine, and spermine.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cell Membrane; DNA; Escherichia coli; Ornithine Decarboxylase; Osmolar Concentration; Polyamines; Potassium; Protein Biosynthesis; Putrescine; Ribosomes; RNA; Species Specificity; Spermidine; Spermidine Synthase; Spermine | 1976 |
Biochemical markers in cancer of the breast.
Topics: Breast Neoplasms; Cadaverine; Carcinoembryonic Antigen; Chorionic Gonadotropin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Guanosine; Humans; Inosine; Methotrexate; Neoplasm Metastasis; Prognosis; Putrescine; Recurrence; Spermidine; Spermine | 1976 |
[Some new aspects of the function of spermidine in animal cells].
Topics: Adenosylmethionine Decarboxylase; Animals; Breast; Cell Division; Chick Embryo; Female; Glucocorticoids; Half-Life; Liver Neoplasms; Male; Milk Proteins; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Prostate; Putrescine; Pyridoxal Phosphate; Rabbits; Rats; RNA; Spermidine; Spermidine Synthase; Spermine | 1975 |
[Presence and function of polyamines in oral tissue and fluid].
Topics: Arginase; Gingival Crevicular Fluid; Humans; Polyamines; Putrescine; Saliva; Salivary Glands; Spermidine; Spermine | 1990 |
Selective aspects of mitochondrial protein turnover.
Topics: Animals; Apoproteins; Biological Transport; Cytochrome c Group; Cytochromes c; Mitochondria; Ornithine Carbamoyltransferase; Proteins; Spermidine; Spermine | 1989 |
Localization and possible function of polyamines in protein and peptide secreting cells.
Topics: Animals; APUD Cells; Cytoplasmic Granules; Exocytosis; Histocytochemistry; Islets of Langerhans; Peptides; Polyamines; Protein Processing, Post-Translational; Proteins; Spermidine; Spermine | 1986 |
Polyamine metabolism and function in the heart.
Topics: Animals; Cardiomegaly; Cell Membrane; Cyclic AMP; Cyclic GMP; Heart; Myocardium; Ornithine Decarboxylase; Phosphorylation; Polyamines; Proteins; Putrescine; Spermidine; Spermine | 1986 |
Regulation of polyamine biosynthetic activity by spermidine and spermine analogs--a novel antiproliferative strategy.
Topics: Animals; Antineoplastic Agents; Cell Division; Humans; Oncogenes; Polyamines; Spermidine; Spermine; Transfection | 1988 |
[Cancer metastasis and polyamines].
Topics: Adenosylmethionine Decarboxylase; Animals; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Neoplasm Metastasis; Neoplasms, Experimental; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1985 |
Metabolism and function of polyamines.
Topics: Acetyltransferases; Animals; Cell Differentiation; DNA Replication; Female; Mammary Glands, Animal; Mice; Ornithine Decarboxylase; Polyamines; Pregnancy; Protein Biosynthesis; Putrescine; Rats; Spermidine; Spermine; Transcription, Genetic | 1985 |
Polyamine biosynthesis in primary tumors of human central nervous system: review of current knowledge.
Topics: Adenosylmethionine Decarboxylase; Brain Neoplasms; Erythrocytes; Humans; Ornithine Decarboxylase; Polyamines; Prognosis; Putrescine; Spermidine; Spermine | 1985 |
The physiology of the polyamines and related compounds.
Topics: DNA; Escherichia coli; Models, Structural; Nucleic Acid Conformation; Oxidation-Reduction; Plant Growth Regulators; Plants; Polyamines; Protein Binding; RNA; Semen; Spermidine; Spermine | 1972 |
New aspects of polyamine biosynthesis in eukaryotic organisms.
Topics: Animals; Azotobacter; Carboxy-Lyases; Carcinoma, Hepatocellular; Catalysis; Chickens; Escherichia coli; Female; Humans; Hydrogen-Ion Concentration; Liver Neoplasms; Macromolecular Substances; Magnesium; Male; Polyamines; Propylamines; Prostate; Putrescine; Rabbits; Rats; S-Adenosylmethionine; Saccharomyces cerevisiae; Spermidine; Spermine; Transferases; Xenopus | 1972 |
Macrocyclic spermidine and spermine alkaloids.
Topics: Alkaloids; Chemical Phenomena; Chemistry; Cyclization; Lactams; Models, Chemical; Plant Extracts; Plants, Medicinal; Spermidine; Spermine | 1973 |
The roles of the polyamines, putrescine, spermidine, and spermine in normal and malignant tissues.
Topics: Animals; Carboxy-Lyases; DNA-Directed RNA Polymerases; Drug Synergism; Humans; Neoplasms; Ornithine; Polyamines; Putrescine; RNA; S-Adenosylmethionine; Spermidine; Spermine; Xenopus | 1973 |
Polyamines and the liver.
Topics: Animals; Carboxy-Lyases; Disease Models, Animal; DNA; Liver; Liver Regeneration; Polyamines; Putrescine; Rats; RNA; S-Adenosylmethionine; Spermidine; Spermine; Starvation; Tyrosine Decarboxylase | 1972 |
Regulation of amino acid decarboxylation.
Topics: Amino Acids; Animals; Arginine; Biogenic Amines; Carboxy-Lyases; Diamines; Enzyme Activation; Escherichia coli; Glutamates; Histidine; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver; Lysine; Organ Specificity; Ornithine; Pimelic Acids; Putrescine; S-Adenosylmethionine; Spermidine; Spermine | 1974 |
Biosynthesis and metabolism of 1,4-diaminobutane, spermidine, spermine, and related amines.
Topics: Acylation; Amidines; Amine Oxidase (Copper-Containing); Animals; Arginine; Bacteria; Carboxy-Lyases; Escherichia coli; Fungi; Ornithine; Plants; Polyamines; Propylamines; Putrescine; Rats; RNA; Spermidine; Spermine; Transferases; Ureohydrolases; Viruses | 1972 |
The occurrence, metabolism and functions of amines in plants.
Topics: Alkaloids; Amination; Amines; Amino Acids; Biodegradation, Environmental; Carbon Isotopes; Decarboxylation; Epinephrine; Fungi; Histamine; Leucine; Norepinephrine; Oxidation-Reduction; Oxygen Consumption; Phenethylamines; Plant Growth Regulators; Plant Viruses; Plants; Polyamines; Serotonin; Spermidine; Spermine; Tyramine; Valine | 1971 |
Polyamines spermidine and spermine as modulators of calcium-dependent immune processes.
Topics: Adenosine Diphosphate; Animals; Biological Transport; Calcium; Cystic Fibrosis; Enzyme Induction; gamma-Glutamyltransferase; Hypersensitivity; Lymphocyte Activation; Mast Cells; Membrane Fluidity; Ornithine Decarboxylase; Platelet Aggregation; Spermidine; Spermine | 1980 |
Transglutaminase-mediated covalent attachment of polyamines to proteins: mechanisms and potential physiological significance.
Topics: Animals; Factor XIII; gamma-Glutamyltransferase; Guinea Pigs; Humans; Liver; Male; Polyamines; Protein Binding; Proteins; Putrescine; Semen; Spermidine; Spermine; Substrate Specificity | 1980 |
Prostate cancer. Hormonal relationships, receptors, and tumour markers.
Topics: Acid Phosphatase; Aged; Androgens; Humans; Male; Polyamines; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Receptors, Steroid; Spermidine; Spermine; Testosterone | 1981 |
Role of polyamines in the control of cell proliferation and differentiation.
Topics: Animals; Cell Differentiation; Cell Division; Chick Embryo; Cricetinae; DNA; Escherichia coli; Female; Haemophilus influenzae; Mice; Mutation; Polyamines; Protein Biosynthesis; Putrescine; Rats; RNA; Spermidine; Spermine | 1981 |
Polyamines.
Topics: Adenosylmethionine Decarboxylase; Animals; Arginase; Aspergillus nidulans; Carboxy-Lyases; Cloning, Molecular; DNA; Escherichia coli; Lysine; Mutation; Neoplasms; Neurospora crassa; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Physarum; Plants; Polyamines; Protein Biosynthesis; Protein Kinases; Protein Processing, Post-Translational; Putrescine; RNA; Saccharomyces cerevisiae; Spermidine; Spermidine Synthase; Spermine; Spermine Synthase | 1984 |
[Polyamines and cancers (author's transl)].
Topics: Adult; Animals; Brain Neoplasms; Child; Erythrocytes; Female; Humans; Male; Mice; Neoplasms; Neoplasms, Nerve Tissue; Polyamines; Prostatic Neoplasms; Rats; Spermidine; Spermine; Stomach Neoplasms | 1981 |
Clinical relevance of polyamines.
Topics: Animals; Cadaverine; Cystic Fibrosis; Diamines; Female; Growth Disorders; Humans; Kidney Failure, Chronic; Liver Diseases; Neoplasms; Neoplasms, Experimental; Polyamines; Polycythemia Vera; Pregnancy; Pregnancy Complications; Putrescine; Spermidine; Spermine; Tissue Distribution | 1983 |
Polyamines in mammalian ageing: an oncological problem, too? A review.
Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Humans; Male; Neoplasms; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Spermidine; Spermine; Tissue Distribution | 1984 |
[Polyamine analysis of blood, tissue and gastric juice and its clinical significance. II. Analysis of tissue polyamines and their derivatives and their significance].
Topics: Humans; Neoplasms; Polyamines; Putrescine; Spermidine; Spermine; Tissue Distribution | 1984 |
[Biological dynamics and metabolism of polyamines].
Topics: Animals; Humans; Kinetics; Mice; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
[Microbial amine oxidase].
Topics: Amine Oxidase (Copper-Containing); Aspergillus niger; Oxidoreductases Acting on CH-NH Group Donors; Penicillium; Penicillium chrysogenum; Polyamine Oxidase; Spermidine; Spermine; Ureohydrolases | 1984 |
The odour of non-specific vaginitis: a review.
Topics: Cadaverine; Coitus; Female; Gardnerella vaginalis; Haemophilus; Haemophilus Infections; Humans; Metronidazole; Odorants; Putrescine; Spermidine; Spermine; Vaginitis | 1982 |
On the role of GABA in vertebrate polyamine metabolism.
Topics: Amine Oxidase (Copper-Containing); Animals; Brain; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Kinetics; Liver; Mice; Ornithine; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Trout | 1980 |
Trends in the biochemical pharmacology of 5'-deoxy-5'-methylthioadenosine.
Topics: Adenosine; Animals; Deoxyadenosines; Female; Humans; Male; Neoplasms; Purine-Nucleoside Phosphorylase; Rats; Ribosemonophosphates; S-Adenosylmethionine; Spermidine; Spermine; Thioglycosides; Thionucleosides | 1982 |
Polyamines effect on subcellular fractionation of rat liver homogenate.
Topics: Animals; Cell Fractionation; Centrifugation, Density Gradient; Liver; Male; Microsomes, Liver; Rats; Spermidine; Spermine; Subcellular Fractions | 1980 |
[Polyamines and malignant diseases (author's transl)].
Topics: Cell Division; Humans; Kinetics; Neoplasms; Polyamines; Putrescine; Spermidine; Spermine | 1980 |
Polyamine metabolites and conjugates in man and higher animals: a review of the literature.
Topics: Acetylation; Animals; Biotransformation; Humans; Kidney; Liver; Oxidation-Reduction; Polyamines; Putrescine; Rats; Spermidine; Spermine; Tissue Distribution | 1980 |
Regulation of the biosynthesis of putrescine, spermidine and spermine in fungi.
Topics: Fungi; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine | 1981 |
The role of dietary polyamines.
Topics: Cadaverine; Cell Division; Diet; Digestive System; DNA; Eflornithine; Humans; Neoplasms; Protein Biosynthesis; Putrescine; RNA; Spermidine; Spermine | 1993 |
Use of aminopropyltransferase inhibitors and of non-metabolizable analogs to study polyamine regulation and function.
Topics: Amino Acid Sequence; Animals; Biological Transport; Cell Division; Drug Design; Humans; Molecular Sequence Data; Molecular Structure; Polyamines; Spermidine; Spermidine Synthase; Spermine | 1995 |
Polyamine transport in cells.
Topics: Animals; Biological Transport; Cells, Cultured; Escherichia coli; Humans; Kinetics; Leukemia L1210; Liver; Lymphocytes; Mice; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1994 |
[Primary structure and biophysical properties of inward rectifier K+ channels].
Topics: Animals; Cloning, Molecular; DNA; Ion Channel Gating; Magnesium; Membrane Potentials; Potassium Channels; Spermidine; Spermine | 1995 |
[Molecular mechanism of the G protein regulation of inwardly rectifying potassium channels].
Topics: Amino Acid Sequence; Animals; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Proteins; Ion Channel Gating; Membrane Potentials; Molecular Sequence Data; Potassium Channels; Potassium Channels, Inwardly Rectifying; Spermidine; Spermine | 1995 |
Ethanol and polyamine metabolism: physiologic and pathologic implications: a review.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Histamine; Humans; Infant, Newborn; Liver; Liver Diseases, Alcoholic; Pregnancy; Putrescine; Spermidine; Spermine | 1997 |
Polyamines in the male reproductive system.
Topics: Acetyltransferases; Animals; Biogenic Polyamines; Cricetinae; Epididymis; Humans; Male; Mammals; Mesocricetus; Mice; Ornithine; Prostate; Putrescine; Rats; Semen; Seminal Vesicles; Spermidine; Spermine; Testis | 1996 |
Polyamines. An introduction.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Amidohydrolases; Animals; Humans; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Spermidine; Spermine | 1998 |
The cellular localization of the L-ornithine decarboxylase/polyamine system in normal and diseased central nervous systems.
Topics: Animals; Central Nervous System; Central Nervous System Diseases; Humans; Neurons; Ornithine Decarboxylase; Polyamines; Putrescine; Reference Values; Spermidine; Spermine | 1999 |
Translational regulation of ornithine decarboxylase and other enzymes of the polyamine pathway.
Topics: Adenosylmethionine Decarboxylase; Animals; Enzymes; Gene Expression Regulation; Humans; Ornithine Decarboxylase; Peptide Initiation Factors; Polyamines; Protein Biosynthesis; Spermidine; Spermine | 1999 |
-Bioactive factors in milk-.
Topics: Biogenic Polyamines; Cytoprotection; Digestive System; Growth; Growth Substances; Hormones; Humans; Infant, Newborn; Lipid Metabolism; Lipoproteins; Liver; Lymphoid Tissue; Milk, Human; Nucleosides; Nucleotides; Spermidine; Spermine | 1998 |
Use of amifostine in hematologic malignancies, myelodysplastic syndrome, and acute leukemia.
Topics: Acute Disease; Amifostine; Animals; Apoptosis; Cytoprotection; Hematologic Neoplasms; Hematopoietic Stem Cells; Humans; Leukemia; Mercaptoethylamines; Molecular Structure; Myelodysplastic Syndromes; Protective Agents; Spermidine; Spermine | 1999 |
Polyamines: mysterious modulators of cellular functions.
Topics: Animals; Escherichia coli; Gene Expression Regulation; Liver; Lymphocytes; Models, Molecular; Polyamines; Putrescine; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; RNA, Transfer; Signal Transduction; Spermidine; Spermine | 2000 |
Oxidation of polyamines and brain injury.
Topics: Amine Oxidase (Copper-Containing); Animals; Brain; Brain Injuries; Cattle; Enzyme Inhibitors; Humans; Mice; Neurons; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Rats; Spermidine; Spermine | 2000 |
Polyamines in human and animal milk.
Topics: Animals; Biological Factors; Cell Differentiation; Cell Division; Humans; Infant; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Intestinal Absorption; Intestinal Mucosa; Milk; Milk, Human; Polyamines; Putrescine; Species Specificity; Spermidine; Spermine | 2000 |
Natural polyamines and their biological consequence in mammals.
Topics: Agmatine; Animals; Biogenic Polyamines; Cadaverine; Humans; Putrescine; Spermidine; Spermine | 2000 |
Polyamines in plant physiology.
Topics: Aging; Carboxy-Lyases; Morphogenesis; Ornithine Decarboxylase; Plant Development; Plant Physiological Phenomena; Plants; Polyamines; Putrescine; Spermidine; Spermine | 1990 |
Meta-analysis of microarrays: interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer.
Topics: Adenosine Monophosphate; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Reproducibility of Results; Spermidine; Spermine | 2002 |
Regulation of Ca2+ channel and phosphatase activities by polyamines in intestinal and vascular smooth muscle--implications for cellular growth and contractility.
Topics: Calcium; Calcium Channels; Cytoskeleton; Humans; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Smooth; Phosphoprotein Phosphatases; Polyamines; Potassium Channels; Putrescine; Spermidine; Spermine | 2002 |
Putrescine, spermidine, spermine, and related polyamine alkaloids.
Topics: Putrescine; Spermidine; Spermine | 2002 |
Polyamine-dependent gene expression.
Topics: Animals; Casein Kinase II; DNA; Gene Expression Regulation; Humans; Nucleic Acid Conformation; Protein Biosynthesis; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Putrescine; Spermidine; Spermine; Transcription, Genetic | 2003 |
SPERMIDINE, SPERMINE, AND RELATED AMINES.
Topics: Alkaloids; Amidines; Amines; Bacteriophages; Cell Biology; Chemical Phenomena; Chemistry; DNA; Enzymes; Flavins; Humans; Metabolism; Pharmacology; Plants; Quinacrine; Spermidine; Spermine; Streptomycin; Viruses | 1964 |
[Clinical usefulness of urinary diacetylpolyamines as novel tumor markers].
Topics: Biomarkers, Tumor; Breast Neoplasms; Colonic Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Predictive Value of Tests; Prognosis; Prostatic Neoplasms; Spermidine; Spermine | 2004 |
How important is the oxidative degradation of spermine?: minireview article.
Topics: Animals; Erythrocytes; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine; Spermine | 2004 |
[Microglial cell death induced by polyamines].
Topics: Animals; Apoptosis; Cell Death; Cells, Cultured; Microglia; Polyamines; Rats; Spermidine; Spermine | 2004 |
Polyamines in renal failure.
Topics: Acrolein; Animals; Humans; Kidney Failure, Chronic; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Spermidine; Spermine | 2006 |
Diacetylated derivatives of spermine and spermidine as novel promising tumor markers.
Topics: Animals; Biomarkers, Tumor; Humans; Neoplasms; Spermidine; Spermine | 2006 |
[Regulation of polyamine and cancer].
Topics: Animals; Biogenic Polyamines; Cell Division; Cyclohexylamines; Humans; Liver Regeneration; Male; Mass Spectrometry; Neoplasms; Prostate; Rats; Spermidine; Spermidine Synthase; Spermine | 2006 |
Biological significance of dietary polyamines.
Topics: Animals; Bacteria, Anaerobic; Biogenic Polyamines; Biological Transport; Cell Division; Diet; DNA; Fermentation; Humans; Intestinal Absorption; Milk, Human; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine | 2007 |
Advances in polyamine research in 2007.
Topics: Ion Channels; Plant Development; Plants; Polyamines; Putrescine; Spermidine; Spermine | 2007 |
Unusual aspects of the polyamine transport system affect the design of strategies for use of polyamine analogues in chemotherapy.
Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Survival; Drug Design; Enzyme Inhibitors; Humans; Mammals; Neoplasms; Polyamines; Spermidine; Spermine | 2007 |
Insights into functional modulation of catalytic RNA activity.
Topics: Anti-Bacterial Agents; Base Sequence; Cations, Divalent; Enzyme Activation; Gene Expression Regulation; Introns; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Protein Conformation; Ribonuclease P; Ribosomes; RNA, Catalytic; RNA, Untranslated; Spermidine; Spermine | 2008 |
Polyamines: ubiquitous polycations with unique roles in growth and stress responses.
Topics: Arabidopsis; Gene Expression Regulation, Plant; Oxidation-Reduction; Phylogeny; Plant Development; Plants; Polyamines; Putrescine; Spermidine; Spermine; Stress, Physiological | 2010 |
Spermine synthase.
Topics: Animals; Chromosomes, Human, X; Humans; Mice; Spermidine; Spermine; Spermine Synthase | 2010 |
Polyamines and cellular metabolism in plants: transgenic approaches reveal different responses to diamine putrescine versus higher polyamines spermidine and spermine.
Topics: Animals; Mice; Plants, Genetically Modified; Populus; Putrescine; Solanum lycopersicum; Spermidine; Spermine | 2010 |
The polyamines: past, present and future.
Topics: Animals; Biochemistry; History, 17th Century; History, 20th Century; Humans; Models, Biological; Polyamines; Spermidine; Spermine | 2009 |
Polyamines on the reproductive landscape.
Topics: Animals; Embryo Implantation; Embryonic Development; Female; Fertilization; Gonadal Steroid Hormones; Humans; Male; Oogenesis; Ovary; Polyamines; Pregnancy; Reproduction; Semen; Sperm Motility; Spermatogenesis; Spermidine; Spermine; Testis; Uterus | 2011 |
Charge deficient analogues of the natural polyamines.
Topics: Acetyltransferases; Animals; Energy Metabolism; Humans; Mitochondria; Polyamines; Reactive Oxygen Species; Spermidine; Spermine | 2014 |
Aliphatic polyamines in physiology and diseases.
Topics: Agmatine; Animals; Disease Models, Animal; Humans; Neoplasms; Ornithine; Putrescine; Spermidine; Spermine | 2014 |
Hydroxylamine derivatives for regulation of spermine and spermidine metabolism.
Topics: Animals; Humans; Hydroxylamine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Spermine | 2013 |
Pharmacological and dietary agents for colorectal cancer chemoprevention: effects on polyamine metabolism (review).
Topics: Anticarcinogenic Agents; Cell Transformation, Neoplastic; Chemoprevention; Colorectal Neoplasms; Humans; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine | 2014 |
Modulation of learning and memory by natural polyamines.
Topics: Animals; Binding Sites; Cognitive Dysfunction; Humans; Learning; Memory; Putrescine; Rats; Spermidine; Spermine | 2016 |
Polyamines and α-Carbonic Anhydrases.
Topics: Antineoplastic Agents; Biological Products; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Coumarins; Drug Design; Humans; Models, Molecular; Molecular Structure; Neoplasms; Putrescine; Spermidine; Spermine; Structure-Activity Relationship | 2016 |
Polyamine catabolism adds fuel to leaf senescence.
Topics: Arabidopsis; Darkness; Ethylenes; Etiolation; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Hordeum; Oxidoreductases Acting on CH-NH Group Donors; Plant Leaves; Polyamine Oxidase; Putrescine; Reactive Oxygen Species; Spermidine; Spermine; Transglutaminases | 2017 |
Polyamine Transport and Synthesis in Trichomonas vaginalis: Potential Therapeutic Targets.
Topics: Amino Acid Sequence; Animals; Antiparasitic Agents; Biological Transport; Drug Delivery Systems; Female; Humans; Polyamines; Spermidine; Spermine; Trichomonas vaginalis; Trichomonas Vaginitis | 2017 |
Modulatory Effects of Exogenously Applied Polyamines on Postharvest Physiology, Antioxidant System and Shelf Life of Fruits: A Review.
Topics: Antioxidants; Ethylenes; Fruit; Plant Development; Plants, Genetically Modified; Polyamines; Putrescine; Spermidine; Spermine | 2017 |
Polyamine Deacetylase Structure and Catalysis: Prokaryotic Acetylpolyamine Amidohydrolase and Eukaryotic HDAC10.
Topics: Acetylation; Amidohydrolases; Aminohydrolases; Animals; Biogenic Polyamines; Catalysis; Catalytic Domain; Eukaryotic Cells; Histone Deacetylases; Humans; Prokaryotic Cells; Protein Structural Elements; Putrescine; Spermidine; Spermine; Substrate Specificity | 2018 |
Prevention of Atherosclerosis by the Induction of Microbial Polyamine Production in the Intestinal Lumen.
Topics: Arginine; Atherosclerosis; Bacteria; Gastrointestinal Microbiome; Humans; Hyperemia; Putrescine; Spermidine; Spermine; Yogurt | 2020 |
Perceptions and Misconceptions in Molecular Recognition: Key Factors in Self-Assembling Multivalent (SAMul) Ligands/Polyanions Selectivity.
Topics: DNA; Heparin; Hydrophobic and Hydrophilic Interactions; Methylamines; Micelles; Molecular Dynamics Simulation; Nanostructures; Polyelectrolytes; Polymers; Solutions; Spermidine; Spermine; Surface-Active Agents; Thermodynamics | 2020 |
Polyamine biomarkers as indicators of human disease.
Topics: Acrolein; Alzheimer Disease; Apoptosis; Biomarkers; Biotransformation; Cadaverine; Cell Movement; Humans; Leukocytes; Neoplasms; Periodontitis; Putrescine; Renal Insufficiency, Chronic; Spermidine; Spermine | 2021 |
Polyamines of biological fluids of the body and the diagnostic value of their determination in clinical and laboratory researches (review of literature).
Topics: Humans; Laboratories; Polyamines; Putrescine; Spermidine; Spermine | 2021 |
Polyamines: Functions, Metabolism, and Role in Human Disease Management.
Topics: Disease Management; Humans; Polyamines; Putrescine; Spermidine; Spermine | 2021 |
The Potential Role of Spermine and Its Acetylated Derivative in Human Malignancies.
Topics: Acetylation; Biomarkers, Tumor; Humans; Neoplasms; Polyamines; Prognosis; Spermidine; Spermine | 2022 |
Environmental stress tolerance in maize (
Topics: Plants; Polyamines; Spermidine; Spermine; Stress, Physiological; Zea mays | 2023 |
Polyamines in cancer: integrating organismal metabolism and antitumour immunity.
Topics: Animals; Humans; Mammals; Neoplasms; Polyamines; Putrescine; Spermidine; Spermine; Tumor Microenvironment | 2022 |
Polyamine metabolism and transport in gut microbes.
Topics: Animals; Biological Transport; Escherichia coli; Gastrointestinal Microbiome; Mice; Polyamines; Putrescine; Spermidine; Spermine | 2022 |
The Association between Spermidine/Spermine N
Topics: Acetyltransferases; Animals; Humans; Mammals; Neoplasms; Polyamines; Spermidine; Spermine | 2022 |
Polyamines and Their Metabolism: From the Maintenance of Physiological Homeostasis to the Mediation of Disease.
Topics: Animals; Homeostasis; Mice; Nucleic Acids; Polyamines; Spermidine; Spermine | 2022 |
Recent Advances in Fluorescent Methods for Polyamine Detection and the Polyamine Suppressing Strategy in Tumor Treatment.
Topics: Humans; Neoplasms; Polyamines; Putrescine; Spermidine; Spermine | 2022 |
Polyamines and Physical Activity in Musculoskeletal Diseases: A Potential Therapeutic Challenge.
Topics: Aged; Animals; Humans; Mice; Muscular Atrophy; Musculoskeletal Diseases; Polyamines; Sarcopenia; Spermidine; Spermine | 2023 |
Polyamines and hormesis: Making sense of a dose response dichotomy.
Topics: Animals; Hormesis; Polyamines; Putrescine; Spermidine; Spermine | 2023 |
Polyamine-Derived Aminoaldehydes and Acrolein: Cytotoxicity, Reactivity and Analysis of the Induced Protein Modifications.
Topics: Acrolein; Aldehydes; Polyamines; Spermidine; Spermine | 2023 |
The Molecular Role of Polyamines in Age-Related Diseases: An Update.
Topics: Polyamines; Putrescine; Spermidine; Spermine | 2023 |
9 trial(s) available for spermine and spermidine
| Article | Year |
|---|---|
Dose de-escalation chemoprevention trial of alpha-difluoromethylornithine in patients with colon polyps.
Topics: Administration, Oral; Adult; Aged; Biogenic Polyamines; Colonic Polyps; Colorectal Neoplasms; Drug Administration Schedule; Eflornithine; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Putrescine; Spermidine; Spermine | 1994 |
Effect of alpha-difluoromethylornithine on rectal mucosal levels of polyamines in a randomized, double-blinded trial for colon cancer prevention.
Topics: Adult; Aged; Aged, 80 and over; Anticarcinogenic Agents; Audiometry; Colonic Neoplasms; Double-Blind Method; Eflornithine; Female; Hearing; Humans; Intestinal Mucosa; Male; Middle Aged; Polyamines; Putrescine; Spermidine; Spermine; Time Factors; Treatment Outcome | 1998 |
Alpha-difluoromethylornithine as treatment for metastatic breast cancer patients.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Eflornithine; Female; Humans; Middle Aged; Neoplasm Staging; Polyamines; Putrescine; Receptors, Estrogen; Spermidine; Spermine; Time Factors | 1999 |
Alpha-difluoromethylornithine and polyamine levels in the human prostate: results of a phase IIa trial.
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Eflornithine; Enzyme Inhibitors; Humans; Male; Polyamines; Prostate-Specific Antigen; Prostatic Neoplasms; Putrescine; Spermidine; Spermine | 2001 |
Increased red blood cell polyamines in ALS and Parkinson's disease.
Topics: Amyotrophic Lateral Sclerosis; Biogenic Polyamines; Erythrocytes; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Putrescine; Spermidine; Spermine; Time Factors | 2002 |
Levels of rectal mucosal polyamines and prostaglandin E2 predict ability of DFMO and sulindac to prevent colorectal adenoma.
Topics: Adenoma; Aged; Anticarcinogenic Agents; Biomarkers, Pharmacological; Biopsy; Colonoscopy; Colorectal Neoplasms; Dinoprostone; Double-Blind Method; Drug Therapy, Combination; Eflornithine; Enzyme Inhibitors; Female; Humans; Intestinal Mucosa; Likelihood Functions; Logistic Models; Male; Middle Aged; Neoplasms, Second Primary; Polyamines; Putrescine; Rectum; Spermidine; Spermine; Sulindac; Time Factors; Treatment Outcome | 2010 |
In vitro and in vivo efficacy of sulfo-carrabiose, a sugar-based cosmetic ingredient with anti-cellulite properties.
Topics: Adipocytes; Adipose Tissue; Adult; Carrageenan; Cell Growth Processes; Cosmetics; Double-Blind Method; Female; Humans; Middle Aged; Spermidine; Spermine; Thigh; Young Adult | 2011 |
High-Dose Spermidine Supplementation Does Not Increase Spermidine Levels in Blood Plasma and Saliva of Healthy Adults: A Randomized Placebo-Controlled Pharmacokinetic and Metabolomic Study.
Topics: Adult; Animals; Chromatography, Liquid; Dietary Supplements; Humans; Mammals; Plasma; Polyamines; Putrescine; Saliva; Spermidine; Spermine; Tandem Mass Spectrometry | 2023 |
Effects of dietary protein content and crystalline amino acid supplementation patterns in low protein diets on intestinal bacteria and their metabolites in weaned pigs raised under Different sanitary conditions.
Topics: Amino Acids; Ammonia; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Bacteria; Diet; Diet, Protein-Restricted; Dietary Proteins; Dietary Supplements; Female; RNA, Ribosomal, 16S; Spermidine; Spermine; Swine | 2023 |
2415 other study(ies) available for spermine and spermidine
| Article | Year |
|---|---|
alpha-Methyl polyamines: metabolically stable spermidine and spermine mimics capable of supporting growth in cells depleted of polyamines.
Topics: Animals; Cell Division; Cell Line, Transformed; Colonic Neoplasms; Eflornithine; Humans; Leukemia L1210; Methylation; Mice; Putrescine; Spermidine; Spermine; Spermine Synthase; Substrate Specificity; Tumor Cells, Cultured | 1992 |
Synthesis and DNA-binding properties of polyamine analogues.
Topics: Alkylation; Antineoplastic Agents; Base Composition; Cell Division; DNA; Ethidium; HeLa Cells; Molecular Structure; Polyamines; Spermine; Structure-Activity Relationship | 1991 |
Control of rectification and permeation by residues in two distinct domains in an inward rectifier K+ channel.
Topics: Amino Acids; Animals; Electric Conductivity; Electrochemistry; Female; Magnesium; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Oocytes; Polyamines; Polymerase Chain Reaction; Potassium; Potassium Channels; Spermidine; Structure-Activity Relationship; Thermodynamics; Xenopus laevis | 1995 |
Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification.
Topics: Animals; Cells, Cultured; Cloning, Molecular; Cytoplasm; Electrophysiology; Oocytes; Polyamines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Xenopus | 1994 |
Neuroactive polyamine wasp toxins: nuclear magnetic resonance spectroscopic analysis of the protolytic properties of philanthotoxin-343.
Topics: Carbon Isotopes; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Phenols; Polyamines; Protons; Wasp Venoms | 1996 |
Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.
Topics: Animals; Base Sequence; Biological Transport; Carrier Proteins; Cations; Choline; Electric Conductivity; Kidney; Lidocaine; Membrane Potentials; Membrane Proteins; Molecular Sequence Data; Niacinamide; Organic Cation Transporter 1; Pyridinium Compounds; Rats; Recombinant Proteins; Substrate Specificity | 1996 |
Boron-containing polyamines as DNA targeting agents for neutron capture therapy of brain tumors: synthesis and biological evaluation.
Topics: Animals; Antineoplastic Agents; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; DNA; Female; Glioma; Pregnancy; Rats; Rats, Inbred F344; Spermidine; Spermine; Structure-Activity Relationship; Tumor Cells, Cultured | 1997 |
Synthesis and biological evaluation of boron-containing polyamines as potential agents for neutron capture therapy of brain tumors.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cattle; DNA; Glioma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Radiopharmaceuticals; Rats; Spermidine; Tissue Distribution; Transplantation, Heterologous; Tumor Cells, Cultured | 1999 |
Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations.
Topics: Animals; Biological Transport, Active; Carrier Proteins; Cell Line; Gene Expression; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Oocytes; Organic Cation Transport Proteins; Quinidine; RNA, Messenger; Symporters; Tetraethylammonium Compounds; Xenopus laevis | 1999 |
Design and semisynthesis of spermine-sensitive Ribonuclease S'.
Topics: Amino Acid Sequence; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Denaturation; Protein Structure, Secondary; Ribonucleases; Spermine; Temperature | 1999 |
Synthesis of spermidine and norspermidine dimers as high affinity polyamine transport inhibitors.
Topics: Biological Transport; Cross-Linking Reagents; Dimerization; Humans; Polyamines; Spermidine; Structure-Activity Relationship; Tumor Cells, Cultured | 1999 |
Amino acid/spermine conjugates: polyamine amides as potent spermidine uptake inhibitors.
Topics: Amino Acids; Antineoplastic Agents; Biological Transport; Drug Interactions; Drug Screening Assays, Antitumor; Eflornithine; Humans; Lysine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine; Structure-Activity Relationship; Tumor Cells, Cultured | 2001 |
Synthesis of bis-spermine dimers that are potent polyamine transport inhibitors.
Topics: Antineoplastic Agents; Biological Transport; Cell Division; Cross-Linking Reagents; Dimerization; Drug Design; Drug Evaluation, Preclinical; Humans; Polyamines; Spermidine; Spermine; Structure-Activity Relationship; Tumor Cells, Cultured | 2002 |
Molecular requirements for targeting the polyamine transport system. Synthesis and biological evaluation of polyamine-anthracene conjugates.
Topics: Amines; Animals; Anthracenes; Antineoplastic Agents; Biological Transport; Carrier Proteins; Cell Line; Cricetinae; Fluorescent Dyes; Mice; Microscopy, Fluorescence; Polyamines; Structure-Activity Relationship; Tumor Cells, Cultured | 2003 |
Xylylated dimers of putrescine and polyamines: influence of the polyamine backbone on spermidine transport inhibition.
Topics: Biological Transport; Dimerization; Polyamines; Putrescine; Spermidine; Xylenes | 2003 |
Effect of polyamine homologation on the transport and biological properties of heterocyclic amidines.
Topics: Amidines; Amine Oxidase (Copper-Containing); Animals; Biological Transport; Calmodulin; Cell Line, Tumor; Cell Proliferation; CHO Cells; Cricetinae; Cyclization; Drug Screening Assays, Antitumor; Eflornithine; Guanidines; In Vitro Techniques; Mice; Molecular Structure; Polyamines; Structure-Activity Relationship; Time Factors | 2006 |
Polyamine effects on antibiotic susceptibility in bacteria.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Drug Resistance, Bacterial; Drug Synergism; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Polyamines; Spermine; Staphylococcus aureus | 2007 |
Synthesis and cytotoxic activities of usnic acid derivatives.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzofurans; Carrier Proteins; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Humans; Mice; Polyamines; Structure-Activity Relationship | 2008 |
Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseases.
Topics: Amines; Animals; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cholestanols; Dendrites; Drug Discovery; Humans; Mice; Neoplasms; Neurodegenerative Diseases; Spermidine; Stereoisomerism; Sterols | 2009 |
Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule.
Topics: Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Humans; Isoenzymes; Models, Molecular; Polyamines; Spermine; Structure-Activity Relationship; Water; Zinc | 2010 |
Synthesis and biological evaluation of new C-10 substituted dithranol pleiotropic hybrids.
Topics: Amides; Animals; Anthralin; Anti-Inflammatory Agents; Antioxidants; Binding Sites; Carrageenan; Cell Line; Cell Proliferation; Cell Survival; Edema; Glycine max; Humans; Keratinocytes; Lipid Peroxidation; Lipoxygenase; Lipoxygenase Inhibitors; Molecular Docking Simulation; Polyamines; Rats | 2015 |
Antibacterial Diamines Targeting Bacterial Membranes.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Caenorhabditis elegans; Cell Membrane; Cell Membrane Permeability; Chemistry Techniques, Synthetic; Diamines; Drug Evaluation, Preclinical; Drug Interactions; Escherichia coli; HEK293 Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus | 2016 |
Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase IIα.
Topics: Adenosine Triphosphate; Antigens, Neoplasm; Antineoplastic Agents; Binding Sites; Catalysis; Catalytic Domain; DNA; DNA Cleavage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Humans; Molecular Docking Simulation; Nucleic Acid Conformation; Polyamines; Topoisomerase II Inhibitors; Xanthones | 2017 |
Stabilizing effect of divalent metal ions on virions of southern bean mosaic virus.
Topics: Calcium; Edetic Acid; Hydrogen-Ion Concentration; Magnesium; Mosaic Viruses; Phosphates; Plant Viruses; Protein Denaturation; Spermidine; Spermine; Viral Proteins | 1976 |
Effect of polyamines on the electrokinetic properties of red blood cells.
Topics: Anemia, Sickle Cell; Cadaverine; Erythrocytes; Humans; Hydrogen-Ion Concentration; Leukocytes; Membrane Potentials; Putrescine; Spermidine; Spermine; Trypsin | 1976 |
Properties of a human liver ribonuclease. Inhibition by polynucleotides and specificity for phosphodiester bond cleavage to yield purine nucleosides at the 5' termini.
Topics: Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Magnesium; Molecular Weight; Polyribonucleotides; Putrescine; Ribonucleases; Spermidine; Spermine; Structure-Activity Relationship | 1976 |
Polyamine oxidase from the leaves of cereals.
Topics: Edible Grain; Hordeum; Hydrogen-Ion Concentration; Oxidoreductases Acting on CH-NH Group Donors; Plants; Species Specificity; Spermidine; Spermine; Zea mays | 1976 |
Oxidation of spermidine and spermine in rat liver: purification and properties of polyamine oxidase.
Topics: Animals; Hydrogen-Ion Concentration; Kinetics; Liver; Molecular Weight; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Rats; Spermidine; Spermine; Subcellular Fractions | 1977 |
Regulation of ornithine decarboxylase by diamines in regenerating rat liver.
Topics: Amanitins; Animals; Carboxy-Lyases; Cycloheximide; Diamines; Liver; Liver Regeneration; Male; Ornithine Decarboxylase; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine; Tyrosine Transaminase | 1977 |
Translation of albumin messenger RNA in a cell-free protein-synthesizing system derived from wheat germ.
Topics: Albumins; Animals; Cell-Free System; Hydrogen-Ion Concentration; Kinetics; Liver; Molecular Weight; Osmolar Concentration; Plants; Polyribosomes; Potassium; Protein Biosynthesis; Putrescine; Rats; Ribosomes; RNA, Messenger; Spermidine; Spermine; Triticum | 1977 |
Effects of polyamines on the degradation of ribonucleic acids by polynucleotide phosphorylase of Micrococcus luteus.
Topics: Binding Sites; Heparin; Hydrogen-Ion Concentration; Magnesium; Manganese; Micrococcus; Poly A; Poly C; Poly U; Polyribonucleotide Nucleotidyltransferase; Potassium; RNA; Saccharomyces cerevisiae; Spermidine; Spermine | 1977 |
Occurrence of ornithine decarboxylase and polyamines in cartilage.
Topics: Animals; Carboxy-Lyases; Cartilage; Chick Embryo; Cycloheximide; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Rabbits; Rats; Spermidine; Spermine | 1977 |
Polyamine induced aggregation of DNA.
Topics: Cadaverine; Coliphages; DNA; DNA, Single-Stranded; DNA, Viral; Hydrogen-Ion Concentration; Magnesium; Molecular Weight; Polyamines; Polydeoxyribonucleotides; Potassium Chloride; Species Specificity; Spermidine; Spermine; Structure-Activity Relationship | 1977 |
Base specificity of polyamine binding to synthetic polynucleotides.
Topics: Chemical Phenomena; Chemistry; DNA; Ethidium; Hydrogen-Ion Concentration; Magnesium; Poly A; Poly C; Poly G; Poly U; Polyribonucleotides; Quaternary Ammonium Compounds; Spermidine; Spermine | 1977 |
[Oxidation of putrescine, spermidine and spermine by diamino-oxidase from mouse liver].
Topics: Amine Oxidase (Copper-Containing); Animals; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; Liver; Mice; Oxidation-Reduction; Polyamines; Putrescine; Spermidine; Spermine; Structure-Activity Relationship; Tyramine | 1977 |
Evidence against the view that the central actions of polyamines are indirectly mediated.
Topics: Animals; Brain; Brain Chemistry; Female; Neurotransmitter Agents; Rats; Serum Albumin, Radio-Iodinated; Spermidine; Spermine; Stimulation, Chemical | 1977 |
Catalysis of DNA reassociation by the Escherichia coli DNA binding protein: A polyamine-dependent reaction.
Topics: Calcium; Catalysis; Coliphages; DNA Helicases; DNA Replication; DNA, Bacterial; DNA, Single-Stranded; DNA, Viral; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Magnesium; Polyamines; Spermidine; Spermine | 1977 |
Studies on vaginal malodor. II Laboratory model.
Topics: Amine Oxidase (Copper-Containing); Chromatography, Gas; Contraceptive Devices, Female; Copper; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Monoamine Oxidase; Odorants; Polyamines; Semen; Spermidine; Spermine; Vagina | 1978 |
Inhibition by polyamines of lipid peroxide formation in rat liver microsomes.
Topics: Animals; Ascorbic Acid; Ferrous Compounds; Lipid Metabolism; Magnesium; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Peroxides; Polyamines; Potassium; Putrescine; Rats; Spermidine; Spermine | 1979 |
Putrescine-oxidase activity in adult bovine serum and fetal bovine serum.
Topics: Animals; Cattle; Fetal Blood; Guanidines; Hydrogen-Ion Concentration; Kinetics; Oxidoreductases Acting on CH-NH Group Donors; Putrescine; Spermidine; Spermine | 1979 |
Urinary polyamine levels in human cancer.
Topics: Adenocarcinoma; Adenoma; Bone Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Electrophoresis; Liver Neoplasms; Lung Neoplasms; Male; Neoplasm Metastasis; Neoplasms; Polyamines; Prostatic Hyperplasia; Putrescine; Spermidine; Spermine | 1975 |
Relative usefulness of measuring polyamines in serum, plasma, and urine as biochemical markers of cancer.
Topics: Bleomycin; Cadaverine; Chromatography, Ion Exchange; Cytarabine; Diamines; Humans; Multiple Myeloma; Plasma; Prednisone; Putrescine; Spermidine; Spermine; Teratoma; Vinblastine; Vincristine | 1975 |
Immunolatex visualisation of cell surface Forssman and polyamine antigens.
Topics: Antigens; Cell Membrane; Cells, Cultured; Epitopes; Fluorescent Antibody Technique; Forssman Antigen; Immunoassay; Latex; Microscopy, Electron, Scanning; Microspheres; Polyamines; Putrescine; Spermidine; Spermine | 1976 |
Effect of polaymines on yeast cell-free protein synthesizing system. I. Influence of spermine and spermidine on aminoacyl-tRNA transfer reaction.
Topics: Cell-Free System; Fungal Proteins; Magnesium; Phenylalanine; Ribosomes; RNA, Transfer; Saccharomyces cerevisiae; Spermidine; Spermine | 1976 |
Mouse mammary tumor virus production stimulated by hormones and polyamines in cells grown in semi-synthetic in vitro conditions.
Topics: Bromodeoxyuridine; Cells, Cultured; Dexamethasone; Drug Interactions; Hormones; Insulin; Kinetics; Magnesium; Mammary Tumor Virus, Mouse; Polyamines; Prolactin; RNA-Directed DNA Polymerase; Spermidine; Spermine; Virus Replication | 1977 |
Axonal transport of putrescine, spermidine and spermine in normal and regenerating goldfish optic nerves.
Topics: Animals; Axonal Transport; Goldfish; Nerve Regeneration; Optic Nerve; Putrescine; Retina; Spermidine; Spermine; Superior Colliculi; Time Factors | 1977 |
Altered polyamine profiles in prostatic hyperplasia and in kidney tumors.
Topics: Adult; Aged; Female; Humans; Kidney; Kidney Neoplasms; Male; Middle Aged; Polyamines; Prostate; Prostatic Hyperplasia; Putrescine; Spermidine; Spermine | 1978 |
Polyamines in blood-cells as a cancer marker.
Topics: Female; Humans; Leukocytes; Male; Neoplasms; Plasma; Putrescine; Spermidine; Spermine | 1979 |
Altered polyamines and peptide hormones (FSH, TSH, prolactin, C-peptide) in prostatic hyperplasia and kidney tumors.
Topics: C-Peptide; Follicle Stimulating Hormone; Humans; Kidney; Kidney Neoplasms; Male; Peptides; Polyamines; Prolactin; Prostate; Prostatic Hyperplasia; Putrescine; Spermidine; Spermine; Thyrotropin | 1979 |
Polyamines in blood-cells as cancer markers.
Topics: Adult; Aged; Erythrocytes; Evaluation Studies as Topic; False Positive Reactions; Female; Humans; Male; Middle Aged; Neoplasms; Spermidine; Spermine | 1979 |
Polyamines of Anacystis nidulans and metabolism of exogenous spermidine and spermine.
Topics: Chlorophyll; Cyanobacteria; Polyamines; Putrescine; Spermidine; Spermine | 1978 |
Reversal by aminoguanidine of the inhibition of proliferation of human fibroblasts by spermidine and spermine.
Topics: Amine Oxidase (Copper-Containing); Cell Division; Cells, Cultured; Fibroblasts; Guanidines; Humans; Putrescine; Spermidine; Spermine; Time Factors | 1978 |
Interaction of Escherichia coli ribosome with RNase I--effect of polycationic amines.
Topics: Escherichia coli; Kinetics; Ribonuclease T1; Ribonucleases; Ribosomes; Spermidine; Spermine | 1978 |
Studies on polyamine biosynthesis in Euglena gracilis.
Topics: Adenosylmethionine Decarboxylase; Animals; Euglena gracilis; Models, Chemical; Ornithine Decarboxylase; Polyamines; Spermidine; Spermine | 1979 |
Purification and characterization of S-adenosyl-L-methionine decarboxylase from mouse mammary gland and liver.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drug Stability; Female; Immunoassay; Immunodiffusion; Kinetics; Liver; Mammary Glands, Animal; Mice; Mitoguazone; Organ Specificity; Putrescine; Spermidine; Spermine | 1979 |
Polyamine and nucleoprotein correlations in hypertrophied and perfused heart.
Topics: Animals; Cardiomegaly; Histones; In Vitro Techniques; Myocardium; Nucleoproteins; Perfusion; Physical Exertion; Polyamines; Putrescine; Rats; RNA; Spermidine; Spermine; Subcellular Fractions; Swimming | 1975 |
Biochemical aspects of experimental cardiac hypertrophy.
Topics: Adenosine Triphosphatases; Animals; Cardiomegaly; Disease Models, Animal; DNA; Myocardial Contraction; Myocardium; Myosins; Putrescine; Pyrimidine Nucleotides; Rats; RNA; Spermidine; Spermine | 1976 |
Synthetic polyamines added to cultures containing bovine sera reversibly inhibit in vitro parameters of immunity.
Topics: Blood; Cells, Cultured; Concanavalin A; Culture Media; Cytotoxicity Tests, Immunologic; DNA; Immunity, Cellular; Lectins; Lipopolysaccharides; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocytes; Polysaccharides, Bacterial; Spermidine; Spermine; Spleen | 1977 |
Inhibition of Na,K-ATPase from chick brain by polyamines.
Topics: Adenosine Triphosphatases; Allosteric Regulation; Animals; Brain; Chick Embryo; Enzyme Activation; Kinetics; Potassium; Putrescine; Sodium; Spermidine; Spermine; Time Factors | 1977 |
Isolation of putrescine-requiring mutants of Neurospora crassa.
Topics: Crosses, Genetic; Genetic Complementation Test; Genetic Linkage; Mutation; Neurospora; Neurospora crassa; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine | 1977 |
Polyamine-induced actin polymerization.
Topics: Actins; Adenosine Triphosphatases; Animals; Guanidines; Kinetics; Macromolecular Substances; Muscles; Polyamines; Protein Binding; Protein Conformation; Putrescine; Rabbits; Spermidine; Spermine; Structure-Activity Relationship | 1978 |
Is lymphocytic chalone activity restricted to a spermine-protein complex?
Topics: Animals; Growth Inhibitors; Lymphocyte Activation; Mice; Proteins; Spermidine; Spermine | 1979 |
Immunosuppressive activity of a purified spleen extract (lymphocytic chalone?) is not due to polyamines spermine and spermidine.
Topics: Animals; Dermatitis, Contact; DNA; Growth Inhibitors; Hemolytic Plaque Technique; Immunosuppression Therapy; Mice; Mice, Inbred DBA; Spermidine; Spermine; Spleen; Thymidine; Tissue Extracts | 1979 |
Granulocytic chalone is not a polyamine complex.
Topics: Animals; Bone Marrow; Granulocytes; Growth Inhibitors; Humans; Leukemia L1210; Leukemia, Experimental; Mice; Polyamines; Rats; Spermidine; Spermine; Thymidine | 1979 |
An improved and easy technique for polyamine determination in biological samples. Application to cell-free system from hypertrophied rat heart.
Topics: Animals; Cardiomegaly; Chromatography, Ion Exchange; Heart; Kinetics; Myocardium; Peptide Initiation Factors; Polyamines; Polyribosomes; Putrescine; Rats; Reticulocytes; Ribosomes; Spectrophotometry, Ultraviolet; Spermidine; Spermine; Triiodothyronine | 1979 |
Specific increase in polyamine levels in chick embryo cells transformed by Rous sarcoma virus.
Topics: Allantois; Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Chick Embryo; Chorion; Embryo, Mammalian; Embryo, Nonmammalian; Extraembryonic Membranes; Fibroblasts; Newcastle disease virus; Orthomyxoviridae; Polyamines; Putrescine; Spermidine; Spermine; Temperature; Vaccinia virus | 1975 |
Effect of salts and polyamines on T4 polynucleotide kinase.
Topics: Coliphages; DNA Viruses; Enzyme Activation; Enzyme Induction; Escherichia coli; Kinetics; Osmolar Concentration; Phosphotransferases; Polyamines; Polynucleotide 5'-Hydroxyl-Kinase; Potassium Chloride; Salts; Sodium Chloride; Spermidine; Spermine | 1975 |
Synthesis of Superhelical Simian Virus 40 Deoxyribonucleic Acid in Cell Lysates*.
Topics: Ammonium Sulfate; Animals; Calcium; Cell Line; Cell-Free System; Centrifugation, Density Gradient; Chloromercuribenzoates; Deoxyribonucleases; DNA Replication; DNA, Circular; DNA, Viral; Edetic Acid; Ethylmaleimide; Haplorhini; Kidney; Kinetics; Nucleic Acid Conformation; Osmolar Concentration; Potassium; Potassium Chloride; Simian virus 40; Spermidine; Spermine; Sulfates; Time Factors | 1975 |
Cell cycle specific fluctuations in adenosine 3':5'-cyclic monophosphate and polyamines of Chinese hamster cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Cell Line; Cricetinae; Cyclic AMP; Ornithine; Ornithine Decarboxylase; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Time Factors | 1975 |
Enhanced differential synthesis of proteins in a mammalian cell-free system by addition of polyamines.
Topics: Animals; Ascites; Carbon Radioisotopes; Cell-Free System; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Coliphages; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Leucine; Magnesium; Methionine; Polyamines; Protein Biosynthesis; Putrescine; Rabbits; Reticulocytes; RNA, Messenger; RNA, Ribosomal; Simian virus 40; Sodium Dodecyl Sulfate; Spermidine; Spermine; Sulfur Radioisotopes; Templates, Genetic | 1975 |
Polyamine metabolism in cells infected with herpes simplex virus.
Topics: Animals; Cycloheximide; Emetine; L Cells; Mice; Mitoguazone; Polyamines; Putrescine; Simplexvirus; Spermidine; Spermine; Tritium; Viral Plaque Assay; Virus Replication | 1975 |
Influence of agents that act on DNA and RNA synthesis on the activity of poly(ADP-Rib) polymerase.
Topics: Adenine; Animals; Cell Nucleus; Coturnix; DNA; Ethidium; Female; Formycins; Kinetics; N-Glycosyl Hydrolases; NAD+ Nucleosidase; Oviducts; RNA; Showdomycin; Spermidine; Spermine; Templates, Genetic | 1975 |
Specific inhibition of ouabain sensitive and K+-dependent p-nitrophenylphosphatase by polyamines.
Topics: 4-Nitrophenylphosphatase; Alkaline Phosphatase; Amines; Animals; Cadaverine; Cell Membrane; Enzyme Activation; Glucose-6-Phosphatase; Kidney; Kinetics; Microsomes; Nucleotidases; Ouabain; Phosphoric Monoester Hydrolases; Polyamines; Potassium; Putrescine; Rabbits; Spermidine; Spermine | 1975 |
Polyamine metabolism in normal and in virus-transformed chick embryo fibroblasts.
Topics: Avian Sarcoma Viruses; Carboxy-Lyases; Cell Transformation, Neoplastic; Cells, Cultured; Mutation; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Temperature; Time Factors | 1975 |
Glutamine-dependent carbamoyl phosphate synthetase: polyamines inhibit the activity and modify the activating effect of 5-phosphoribosyl 1-pyrophosphate.
Topics: Animals; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Enzyme Activation; Kinetics; Magnesium; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phosphotransferases; Polyamines; Putrescine; Spermidine; Spermine | 1975 |
Kinetics and effect of salts and polyamines on T4 polynucleotide ligase.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Cadaverine; Coliphages; Diamines; Diphosphates; Escherichia coli; Kinetics; Nucleic Acid Denaturation; Osmolar Concentration; Polynucleotide Ligases; Potassium Chloride; Putrescine; Salts; Spermidine; Spermine | 1975 |
Comparison of mode of activation of guanosine 3':5'-monophosphate-dependent and adenosine 3':5'-monophosphate-dependent protein kinases from silkworm.
Topics: Animals; Binding Sites; Cyclic AMP; Cyclic GMP; Enzyme Activation; Glutathione; Kinetics; Magnesium; Manganese; Mercaptoethanol; Protein Binding; Pupa; Putrescine; Spermidine; Spermine | 1976 |
Changes in serum putrescine and spermidine levels following local radiation to hepatoma 3924A of the rat.
Topics: Animals; Carcinoma, Hepatocellular; Female; Liver Neoplasms; Neoplasms, Experimental; Putrescine; Rats; Rats, Inbred ACI; Spermidine; Spermine | 1976 |
Effects of polyamines on the proliferation of mammalian cells in tissue culture.
Topics: Agmatine; Animals; Carcinoma, Hepatocellular; Cell Division; Culture Techniques; Fibroblasts; Liver; Liver Neoplasms; Mice; Monoamine Oxidase; Oxygen; Peritoneum; Polyamines; Putrescine; Rats; Sarcoma; Spermidine; Spermine; Time Factors | 1975 |
Stimulation of ornithine decarboxylase synthesis and its control by polyamines in regenerating rat liver and cultured rat hepatoma cells.
Topics: Animals; Bucladesine; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Drug Stability; Enzyme Induction; Hot Temperature; Kinetics; Liver; Liver Neoplasms; Liver Regeneration; Neoplasms, Experimental; Ornithine Decarboxylase; Polyamines; Precipitin Tests; Rats; Spermidine; Spermine; Time Factors | 1976 |
Covalent modification of proteins by metabolites of NAD+.
Topics: Adenosine Diphosphate Sugars; Amino Acids; Animals; Chick Embryo; Deoxyribonucleases; Histones; NAD; Nucleoside Diphosphate Sugars; Pentosephosphates; Polylysine; Proteins; Ribosemonophosphates; Schiff Bases; Serum Albumin, Bovine; Spermidine; Spermine | 1976 |
Effect of polyamines on cyclic AMP-dependent and independent protein kinases from mouse epidermis.
Topics: Adipose Tissue; Animals; Cyclic AMP; Enzyme Activation; Female; Kinetics; Liver; Mice; Muscles; Myocardium; Organ Specificity; Protamine Kinase; Protein Kinases; Putrescine; Rabbits; Rats; Skin; Spermidine; Spermine | 1976 |
Comparison of the subacute effects of cadmium exposure upon nucleic acid, cyclic adenosine 3',5'-monophosphate and polyamine metabolism in lung and kidney cortex.
Topics: Animals; Cadmium; Cyclic AMP; Depression, Chemical; DNA; Kidney Cortex; Lung; Male; Polyamines; Putrescine; Rats; RNA; Spermidine; Spermine; Thymidine | 1976 |
Activation of rat liver choline kinase by polyamines.
Topics: Animals; Cadaverine; Choline Kinase; Enzyme Activation; Kinetics; Liver; Male; Membrane Lipids; Phosphotransferases; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1976 |
Biphasic stimulation of polyamine biosynthesis in primary mouse kidney cells by infection with polyoma virus:uncoupling from DNA and rRNA synthesis.
Topics: Adenosylmethionine Decarboxylase; Cell Line; Dactinomycin; DNA; Enzyme Induction; Floxuridine; Ornithine Decarboxylase; Polyamines; Polyomavirus; Protein Biosynthesis; Putrescine; RNA, Ribosomal; Spermidine; Spermine | 1976 |
Regulation of casein synthesis by polyamines in mammary gland explants of mice.
Topics: Animals; Arginine; Caseins; Cyclic AMP; Cyclic GMP; Female; Hydrocortisone; In Vitro Techniques; Insulin; Mammary Glands, Animal; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Phospholipases; Polyamines; Prolactin; Prostaglandins F; Protein Biosynthesis; Putrescine; Spermidine; Spermine; Transcription, Genetic | 1977 |
Effects of polyamines on nucleosidediphosphate kinase activity.
Topics: Animals; Cattle; Enzyme Activation; Liver; Magnesium; Nucleoside-Diphosphate Kinase; Phosphotransferases; Putrescine; Spermidine; Spermine | 1977 |
Regulation of ornithine decarboxylase by ODC-antizyme in HTC cells.
Topics: Cadaverine; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Kinetics; Liver Neoplasms; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Effect of polyamines on ADP-ribosylation of nuclear proteins from rat liver.
Topics: Animals; Cell Nucleus; Edetic Acid; Histones; Liver; Magnesium; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerases; Polyamines; Proteins; Putrescine; Rats; Spermidine; Spermine | 1976 |
Alteration of the intracellular energetic and ionic conditions by mengovirus infection of Ehrlich ascites tumor cells and its influence on protein synthesis in the midphase of infection.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Culture Techniques; Magnesium; Mengovirus; Neoplasm Proteins; Osmolar Concentration; Potassium; Putrescine; Sodium; Spermidine; Spermine | 1977 |
Effects of polyamines and polyanions on a cyclic nucleotide-independent and a cyclic AMP-dependent protein kinase.
Topics: Animals; Chickens; Cyclic AMP; Enzyme Activation; Heparin; Kinetics; Liver; Magnesium; Male; Phosvitin; Poly A; Protein Kinases; Putrescine; RNA, Transfer; Spermidine; Spermine | 1977 |
Inhibition of rabbit skeletal muscle phosphorylase phosphatase by spermine.
Topics: Animals; Dose-Response Relationship, Drug; Kinetics; Muscles; Phosphoric Monoester Hydrolases; Phosphorylase Phosphatase; Putrescine; Rabbits; Spermidine; Spermine | 1977 |
Changes in polyamine levels and protein synthesis rate during rat liver carcinogenesis induced by 4-dimethylaminoazobenzene.
Topics: Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Male; Neoplasm Proteins; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Polyamines; Precancerous Conditions; Putrescine; Rats; Spermidine; Spermine | 1978 |
Effects of intraventricularly administered polyamines spermidine and spermine on sleep-wakefulness cycles in rats.
Topics: Animals; Injections, Intraventricular; Male; Putrescine; Rats; Sleep; Sleep, REM; Spermidine; Spermine; Time Factors; Wakefulness | 1978 |
Streptomycin uptake via an inducible polyamine transport system in Escherichia coli.
Topics: Cyclic AMP; Dinitrophenols; Escherichia coli; Gentamicins; Glucose; Mutation; Polyamines; Putrescine; Spermidine; Spermine; Streptomycin; Sulfhydryl Reagents | 1978 |
Inhibition of phosphorylase phosphatase by polyamines.
Topics: Animals; Cattle; Kinetics; Liver; Myocardium; Phosphoric Monoester Hydrolases; Phosphorylase Phosphatase; Polyamines; Rabbits; Spermidine; Spermine | 1978 |
Polyamines and protein kinase II. Effect of polyamines on cyclic AMP--dependent protein kinase from rat liver.
Topics: Animals; Cyclic AMP; Female; In Vitro Techniques; Liver; Magnesium; Polyamines; Protein Kinase Inhibitors; Putrescine; Rats; Spermidine; Spermine | 1978 |
Effects of polyamines on partial reactions of membrane (Na+ + K+)-ATPase.
Topics: 4-Nitrophenylphosphatase; Adenosine Triphosphate; Animals; Brain; Magnesium; Mitoguazone; Polyamines; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Spermidine; Spermine | 1978 |
Cell-free synthesis of herpes simplex virus DNA: the influence of polyamines.
Topics: Cell Line; Cell-Free System; DNA Replication; DNA, Viral; Kinetics; Magnesium; Putrescine; Simplexvirus; Spermidine; Spermine | 1978 |
Polyamine turnover and leakage during infection of HeLa and L-cells with herpes simplex virus type 1.
Topics: Animals; HeLa Cells; Humans; L Cells; Mice; Simplexvirus; Spermidine; Spermine; Virus Replication | 1978 |
Polyamine metabolism in MRC5 cells infected with different herpesviruses.
Topics: Adenosylmethionine Decarboxylase; Carboxy-Lyases; Cell Line; Cell Transformation, Viral; Cytomegalovirus; Fibroblasts; Herpesviridae; Humans; Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines; Spermidine; Spermine; Virus Replication | 1979 |
Stimulation by polyamines of carbamylphosphate:glucose phosphotransferase and glucose-6-phosphate phosphohydrolase activities of multifunctional glucose-6-phosphatase.
Topics: Ammonium Chloride; Animals; Carbamates; Carbamyl Phosphate; Catalase; Glucose-6-Phosphatase; Kinetics; Male; Microsomes, Liver; Phosphotransferases; Polyamines; Polylysine; Putrescine; Rats; Spermidine; Spermine | 1979 |
Effects of spermine on activity and stability of calcium-dependent guanosine 3',5'-monophosphate phosphodiesterase.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Brain; Calcium; Cattle; Drug Stability; Enzyme Activation; Kinetics; Magnesium; Putrescine; Spermidine; Spermine | 1979 |
Deoxyribonuclease activity found in Epstein--Barr virus producing lymphoblastoid cells.
Topics: Burkitt Lymphoma; Cell Line; Cell Transformation, Viral; Deoxyribonucleases; Herpesvirus 4, Human; Humans; Kinetics; Lymphocytes; Osmolar Concentration; Spermidine; Spermine | 1979 |
Putrescine as a biochemical marker of malignant brain tumors.
Topics: Astrocytoma; Brain Chemistry; Brain Neoplasms; Glioblastoma; Humans; Neoplasms, Nerve Tissue; Putrescine; Spermidine; Spermine; Spinal Cord Neoplasms | 1979 |
Corticotrophin increases cerebral polyamine content.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Brain; Kinetics; Male; Mice; Organ Specificity; Putrescine; Spermidine; Spermine | 1979 |
Kinetics and distribution of tritiated putrescine in the domestic cat.
Topics: Animals; Astrocytoma; Brain Neoplasms; Cats; Dose-Response Relationship, Drug; Glioblastoma; Kinetics; Mathematics; Putrescine; Rats; Spermidine; Spermine; Tritium | 1979 |
The effects of polyamines on a residue-specific human plasma ribonuclease.
Topics: Calcium; Cytidine Monophosphate; Humans; Hydrogen-Ion Concentration; Liver; Magnesium; Molecular Weight; Oligonucleotides; Phosphates; Polyamines; Polynucleotides; Ribonucleases; RNA; RNA, Bacterial; Spermidine; Spermine | 1975 |
Polyamine activation of staphylococcal nuclease.
Topics: Calcium; Deoxyribonucleases; Enzyme Activation; Guanine Nucleotides; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Polynucleotides; Protein Denaturation; Putrescine; Ribonucleases; Spermidine; Spermine; Staphylococcus | 1975 |
Oxidation of polymines by diamine oxidase from human seminal plasma.
Topics: Amine Oxidase (Copper-Containing); Cell Movement; Electrophoresis, Polyacrylamide Gel; Histamine; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Male; Molecular Weight; Oxidation-Reduction; Polyamines; Putrescine; Semen; Spermatozoa; Spermidine; Spermine | 1975 |
Effect of polyamines on isoleucyl-tRNA formation by rat-liver isoleucyl-tRNA synthetase.
Topics: Amino Acyl-tRNA Synthetases; Animals; Isoleucine-tRNA Ligase; Kinetics; Liver; Magnesium; Putrescine; Rats; Ribosomes; RNA, Transfer, Amino Acyl; Spermidine; Spermine | 1978 |
Elevated levels of polyamines and histamine in adenocarcinomas of the thyroid.
Topics: Adenocarcinoma; Adenoma; Adult; DNA; Female; Graves Disease; Histamine; Humans; Middle Aged; Polyamines; Putrescine; Spermidine; Spermine; Thyroid Gland; Thyroid Neoplasms; Thyroiditis, Autoimmune | 1978 |
Polyamine and magnesium effects on mitochondrial respiration in control and heat-acclimated rats.
Topics: Acclimatization; Animals; Hot Temperature; Ketoglutaric Acids; Magnesium; Mitochondria, Liver; Oxygen Consumption; Polyamines; Rats; Spermidine; Spermine | 1978 |
Bone marrow polyamines in children with acute leukemia as related to remission status, therapy, and cellularity of specimens.
Topics: Adolescent; Antineoplastic Agents; Bone Marrow; Child; Child, Preschool; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Polyamines; Putrescine; Remission, Spontaneous; Spermidine; Spermine | 1977 |
Polyamine-pyridoxal Schiff bases in urine.
Topics: Adult; Cadaverine; Chemical Phenomena; Chemistry; Gas Chromatography-Mass Spectrometry; Humans; Isomerism; Polyamines; Putrescine; Pyridoxal; Pyridoxal Phosphate; Schiff Bases; Spermidine; Spermine | 1979 |
Inhibition of lymphocyte proliferation by polyamines requires ruminant-plasma polyamine oxidase.
Topics: Animals; Blood; Cattle; Culture Media; Diamines; Female; Humans; Lymphocyte Activation; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Pregnancy; Putrescine; Rats; Spermidine; Spermine; T-Lymphocytes; Thymidine | 1979 |
Effects of polyamines on the activities of Escherichia coli ribonuclease I and II.
Topics: Endonucleases; Escherichia coli; Heparin; Magnesium; Poly A; Poly C; Poly G; Poly U; Polyamines; Potassium; Putrescine; Ribonucleases; Spermidine; Spermine | 1977 |
The effects of 1,4-diaminobutanone on polyamine synthesis in Aspergillus nidulans.
Topics: Adenosylmethionine Decarboxylase; Amines; Aspergillus nidulans; Butanones; Enzyme Activation; Kinetics; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Structure-Activity Relationship | 1977 |
[The role of polyamines in protein biosynthesis (author's transl)].
Topics: Escherichia coli; Polyamines; Protein Biosynthesis; Putrescine; Ribosomes; RNA, Transfer, Amino Acyl; Spermidine; Spermine; Transcription, Genetic | 1977 |
[Measurement of blood polyamines in patients with brain tumor--special reference to relationship between the blood levels of spermidine and spermine, and histological malignancy in patients with glioma (author's transl)].
Topics: Adenoma; Adolescent; Adult; Astrocytoma; Brain Neoplasms; Ependymoma; Glioma; Hemangiosarcoma; Humans; Lymphoma, Large B-Cell, Diffuse; Meningioma; Middle Aged; Neoplasm Metastasis; Neurilemmoma; Pinealoma; Pituitary Neoplasms; Spermidine; Spermine | 1977 |
Isolation and characterization of Saccharomyces cerevisiae mutants deficient in S-adenosylmethionine decarboxylase, spermidine, and spermine.
Topics: Adenosylmethionine Decarboxylase; Carboxy-Lyases; Chromosome Mapping; Genes; Mutation; Putrescine; Saccharomyces cerevisiae; Spermidine; Spermine; Spores, Fungal | 1978 |
Polyamine auxotrophs of Saccharomyces cerevisiae.
Topics: Adenosylmethionine Decarboxylase; Genes; Genetic Complementation Test; Genetic Linkage; Ornithine; Ornithine Decarboxylase; Putrescine; Saccharomyces cerevisiae; Spermidine; Spermine | 1978 |
Spermidine or spermine requirement for killer double-stranded RNA plasmid replication in yeast.
Topics: Adenosylmethionine Decarboxylase; Genotype; Mutation; Plasmids; RNA, Bacterial; Saccharomyces cerevisiae; Species Specificity; Spermidine; Spermine; Transcription, Genetic | 1978 |
Influence of polyamines on the activity of DNA polymerase I from Escherichia coli.
Topics: Cadaverine; Escherichia coli; Kinetics; Poly I; Polyamines; Polyribonucleotides; Putrescine; Spermidine; Spermine; Templates, Genetic | 1978 |
Reversal of palmitoyl coenzyme A-caused inhibition of glucose-6-phosphate dehydrogenase by polyamines.
Topics: Acyl Coenzyme A; Glucosephosphate Dehydrogenase; Kinetics; Palmitoyl Coenzyme A; Polyamines; Putrescine; Saccharomyces cerevisiae; Spermidine; Spermine | 1979 |
Effect of polyamines on protein kinases activities from Trypanosoma cruzi.
Topics: Animals; Depression, Chemical; Enzyme Activation; Molecular Weight; Polyamines; Protein Kinases; Putrescine; Spermidine; Spermine; Trypanosoma cruzi | 1979 |
Polyamine content of a non-aqueously isolated chromosome preparation.
Topics: Chromosomes, Human; Cytological Techniques; DNA, Neoplasm; HeLa Cells; Humans; Metaphase; Spermidine; Spermine | 1979 |
Comparative studies on the increase by polyamines of fidelity of protein synthesis in Escherichia coli and wheat germ cell-free systems.
Topics: Cell-Free System; Escherichia coli; Kinetics; Magnesium; Plants; Poly U; Protein Biosynthesis; Putrescine; Spermidine; Spermine; Triticum | 1979 |
Studies on the restoration of the activities of Ribonucleases by polyamines in the presence of various ribonuclease inhibitors.
Topics: Animals; Aspergillus oryzae; Cattle; Enzyme Activation; Heparin; Horses; Kinetics; Liver; Pancreas; Poly G; Polyribonucleotides; Protein Binding; Putrescine; Rats; Ribonuclease T1; Ribonucleases; Spermidine; Spermine; Submandibular Gland | 1977 |
Long-term surface stimulation of the cerebellum in the monkey. II. Electron microscopic and biochemical observations.
Topics: Animals; Cell Nucleus; Cerebellar Cortex; Electric Stimulation; gamma-Aminobutyric Acid; Haplorhini; Histocytochemistry; Macaca mulatta; Male; Purkinje Cells; Putrescine; Spermidine; Spermine; Synapses; Time Factors | 1977 |
Glycerolipid biosynthesis in rat adipose tissue. Effect of polyamines on triglyceride synthesis.
Topics: Acyltransferases; Adipose Tissue; Animals; Coenzyme A; Diglycerides; Edetic Acid; Hydrolases; Magnesium; Male; Microsomes; Palmitic Acids; Putrescine; Rats; Serum Albumin, Bovine; Spermidine; Spermine; Triglycerides | 1977 |
Polyamine metabolism in the kidneys of castrated and testosterone-treated mice after administration of methylglyoxal bis(guanylhydrazone).
Topics: Animals; Cadaverine; Guanidines; Kidney; Male; Mice; Mitoguazone; Organ Size; Ornithine Decarboxylase; Polyamines; Spermidine; Spermine; Testosterone | 1979 |
Polyamines inhibit DNA methylation in vitro.
Topics: Animals; Cell Nucleus; DNA (Cytosine-5-)-Methyltransferases; Kinetics; Liver; Methyltransferases; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine | 1979 |
Effect of alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on polyamine levels in rat tissues.
Topics: Animals; Carboxy-Lyases; Male; Organ Size; Organ Specificity; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Prostate; Putrescine; Rats; Spermidine; Spermine; Testis; Thymus Gland | 1979 |
Depletion of intracellular putrescine and spermidine by alpha-difluromethylornithine does not inhibit proliferation of 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cell Division; Depression, Chemical; Dose-Response Relationship, Drug; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1979 |
Influence of the naturally occurring polyamines spermine, spermidine and putrescine on the kinetic properties of acetylcholinesterase. Comparative studies with the acetylcholinesterases from the central nervous system of Manduca sexta and of the synaptic
Topics: Acetylcholinesterase; Animals; Brain; Cell Membrane; Central Nervous System; In Vitro Techniques; Insecta; Kinetics; Male; Polyamines; Putrescine; Rats; Species Specificity; Spermidine; Spermine; Synapses | 1979 |
Differential effects of inhibition of polyamine biosynthesis on cell cycle traverse and structure of the prematurely condensed chromosomes of normal and transformed cells.
Topics: Animals; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Chromosomes; Cricetinae; DNA Replication; Female; Fibroblasts; HeLa Cells; Humans; Mitoguazone; Ovary; Polyamines; Spermidine; Spermine | 1979 |
Spermine and spermidine-induced B to A transition of DNA in solution.
Topics: DNA; Nucleic Acid Conformation; Polyamines; Spermidine; Spermine; Structure-Activity Relationship | 1979 |
Counterion-induced condesation of deoxyribonucleic acid. a light-scattering study.
Topics: Chemical Phenomena; Chemistry; Coliphages; DNA, Viral; Light; Mathematics; Nucleic Acid Conformation; Putrescine; Scattering, Radiation; Spermidine; Spermine | 1979 |
Polyamine content and release during the proliferation of Burkitt's lymphoma cells in vitro.
Topics: Autoradiography; Burkitt Lymphoma; Cell Cycle; Cell Division; Cell Line; Cells, Cultured; Humans; Polyamines; Putrescine; Spermidine; Spermine | 1979 |
Bacteriophage phiNS11: a lipid-containing phage of acidophilic thermophilic bacteria. IV. Sedimentation coefficient, diffusion coefficient, partial specific volume, and particle weight of the phage.
Topics: Bacteria; Bacteriophages; DNA, Viral; Fatty Acids; Lipids; Molecular Weight; Spermidine; Spermine; Temperature; Viral Proteins | 1979 |
Amine content of vaginal fluid from untreated and treated patients with nonspecific vaginitis.
Topics: Amines; Amino Acids; Ampicillin; Body Fluids; Butylamines; Cadaverine; Chromatography, Thin Layer; Electrophoresis; Erythromycin Estolate; Female; Histamine; Humans; Methylamines; Metronidazole; Phenethylamines; Putrescine; Spermidine; Spermine; Tyramine; Vagina; Vaginitis | 1979 |
Effect of suramin (Bayer 205) on renal ornithine decarboxylase activity and polyamine concentrations in rats.
Topics: Animals; Carboxy-Lyases; DNA; Kidney; Kinetics; Male; Ornithine Decarboxylase; Polyamines; Rats; RNA; Spermidine; Spermine; Suramin | 1979 |
Correlation between circadian rhythms of polyamine synthesis and cell proliferation in rat liver.
Topics: Amino Acids; Animals; Carboxy-Lyases; Circadian Rhythm; Cycloheximide; Dactinomycin; Enzyme Induction; Insulin; Liver; Liver Glycogen; Male; Mitosis; Ornithine Decarboxylase; Putrescine; Rats; Spermidine; Spermine | 1979 |
Polyamines in eukaryotic peptide initiation.
Topics: Animals; Decapoda; Globins; Kinetics; Peptide Chain Initiation, Translational; Polyamines; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; Spermidine; Spermine | 1979 |
The synthesis and turnover of spermidine and spermine in mouse brain.
Topics: Animals; Brain; Female; Injections, Intraventricular; Mice; Putrescine; Spermidine; Spermine | 1979 |
[Preliminary study of the behavior of urinary polyamines in non-pregnant conditions, in pregnant women and in abortive pathology of the 1st trimester].
Topics: Abortion, Spontaneous; Abortion, Threatened; Adult; Age Factors; Female; Humans; Polyamines; Pregnancy; Pregnancy Trimester, First; Putrescine; Sex Factors; Spermidine; Spermine | 1979 |
Cations and the accessibility of chromatin to nucleases.
Topics: Animals; Cell Fractionation; Cell Nucleus; Chromatin; Deoxyribonucleases; Liver; Magnesium; Micrococcal Nuclease; Rats; Spermidine; Spermine | 1979 |
Lowered cutaneous and urinary levels of polyamines with clinical improvement in treated psoriasis.
Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Aged; Anthralin; Female; Humans; Male; Middle Aged; Polyamines; Psoriasis; Putrescine; Salicylates; Skin; Spermidine; Spermine | 1979 |
Urinary polyamine levels in patients with psoriasis.
Topics: Adult; Epidermis; Humans; Male; Polyamines; Psoriasis; Putrescine; Spermidine; Spermine | 1979 |
Effects of ultraviolet light on epidermal polyamine metabolism.
Topics: Animals; DNA; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Skin; Spermidine; Spermine; Thymidine; Ultraviolet Rays | 1979 |
Synthesis and accumulation of polyamines and S-adenosylmethionine in Chinese cabbage infected by turnip yellow mosaic virus.
Topics: Kinetics; Methionine; Mosaic Viruses; Plants; Putrescine; S-Adenosylmethionine; Spermidine; Spermine | 1979 |
Plasma polyamines determined by negative-ion chemical ionization/mass spectrometry.
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Putrescine; Spermidine; Spermine | 1979 |
Polyamines in mammalian biology and medicine.
Topics: Adenosylmethionine Decarboxylase; Animals; Isoelectric Point; Molecular Conformation; Neoplasms; Ornithine; Polyamines; Protein Biosynthesis; Putrescine; Semen; Sexual Maturation; Spermidine; Spermine; Structure-Activity Relationship | 1979 |
Decreased excretion of polyamines from BHK-21/C13 cells treated with alpha-methylornithine [proceedings].
Topics: Animals; Cell Line; Cricetinae; Kidney; Ornithine; Polyamines; Putrescine; Spermidine; Spermine | 1979 |
Conjugated polyamines in BHK-21/C13 cells, and the effect of inhibition of cell growth rate [proceedings].
Topics: Animals; Cell Division; Cell Line; Cricetinae; Guanosine; Kidney; Mitoguazone; Polyamines; Putrescine; Spermidine; Spermine; Thionucleosides | 1979 |
Effect of polyamines on cell-free protein synthesizing systems from rat cerebral cortex, cerebellum and liver.
Topics: Amino Acids; Animals; Cell-Free System; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Liver; Magnesium; Male; Nerve Tissue Proteins; Polyribosomes; Protein Biosynthesis; Rats; RNA, Ribosomal; RNA, Transfer; Spermidine; Spermine | 1979 |
Isolation and characterization of a polyamine-peptide conjugate from human amniotic fluid.
Topics: Amino Acids; Amniotic Fluid; Chromatography, Gel; Chromatography, High Pressure Liquid; Female; Humans; Hydrolysis; Molecular Weight; Peptides; Polyamines; Pregnancy; Pregnancy Proteins; Pregnancy Trimester, Third; Putrescine; Spectrophotometry, Ultraviolet; Spermidine; Spermine | 1979 |
Structural and enzymological characterization of the homogeneous deoxyribonucleic acid polymerase from Mycoplasma orale.
Topics: DNA-Directed DNA Polymerase; Exonucleases; Molecular Weight; Mycoplasma; Spermidine; Spermine | 1979 |
Inhibition of polyamine accumulation and cell proliferation by derivatives of diaminopropane in Ehrlich ascites cells grown in culture.
Topics: Adenosylmethionine Decarboxylase; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cells, Cultured; Cycloheximide; Diamines; DNA, Neoplasm; Enzyme Activation; Kinetics; Mice; Neoplasm Proteins; Ornithine Decarboxylase Inhibitors; Polyamines; Spermidine; Spermine; Structure-Activity Relationship | 1979 |
[Inhibitors of cathepsin R (ribosomal proteinase). Polyamines as natural inhibitors of the proteinase].
Topics: Animals; Cathepsins; Male; Polyamines; Rats; Ribosomes; Serine; Spermidine; Spermine | 1979 |
Polyamine synthesis and levels during the growth and replication of Leishmania tropica minor and Leishmania aethiopica.
Topics: Animals; Leishmania; Polyamines; Putrescine; Species Specificity; Spermidine; Spermine | 1979 |
Serum and urine polyamines in normal and in short children.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Dwarfism; Female; Growth Disorders; Growth Hormone; Humans; Male; Middle Aged; Polyamines; Putrescine; Spermidine; Spermine; Turner Syndrome | 1979 |
Altered polyamine metabolism in cystic fibrosis.
Topics: Adult; Child; Child, Preschool; Cystic Fibrosis; Female; Heterozygote; Humans; Male; Polyamines; Putrescine; Spermidine; Spermine | 1979 |
Effects of polyamines on in vitro phosphorylation and acetylation of histones of the cerebral cortex of rats of various ages.
Topics: Acetylation; Aging; Animals; Cerebral Cortex; Female; Histones; Phosphorylation; Rats; Spermidine; Spermine | 1979 |
Separation and quantification of urinary di- and polyamines by gas chromatography with electron capture detection.
Topics: Chromatography, Gas; Computers; Diamines; Female; Humans; Male; Methods; Polyamines; Propionates; Putrescine; Spermidine; Spermine; Temperature | 1979 |
Leishmania spp.: cellular levels and synthesis of polyamines during growth cycles.
Topics: Animals; Kinetics; Leishmania; Putrescine; Species Specificity; Spermidine; Spermine | 1979 |
Dynamic and regional aspects of polyamine metabolism in the brain of trout (Salmo irideus Gibb.).
Topics: Animals; Autoradiography; Brain; gamma-Aminobutyric Acid; Polyamines; Putrescine; Salmonidae; Spermidine; Spermine; Trout | 1979 |
RNA and protein synthesis in rat brain during exercise. Effect of arginine and some phosphorylated amino acids.
Topics: Amino Acids; Animals; Arginine; Brain; Nerve Tissue Proteins; Physical Exertion; Rats; RNA; Spermidine; Spermine; Subcellular Fractions; Swimming; Time Factors | 1979 |
Effect of polyamines and Mg++ on poly(ADP-ribose) synthesis and ADP-ribosylation of histones in wheat.
Topics: Adenosine Diphosphate Ribose; Cell Nucleus; Histones; Kinetics; Magnesium; Nucleoside Diphosphate Sugars; Plants; Poly Adenosine Diphosphate Ribose; Putrescine; Spermidine; Spermine; Structure-Activity Relationship; Triticum | 1979 |
Chromatin condensation. Possible dehydrating and stabilizing factors.
Topics: Animals; Cattle; Chemical Precipitation; Chromatin; Desiccation; Magnesium; Sodium; Spermidine; Spermine | 1979 |
Interaction of a casein kinase (G-type) with a specific endogenous inhibitor. Possible target for the regulation of a cyclic nucleotide-independent protein kinase activity by polyamines.
Topics: Adrenal Cortex; Animals; Cadaverine; Caseins; Cattle; Cytosol; Kinetics; Nucleotides, Cyclic; Polyamines; Protein Binding; Protein Kinases; Putrescine; Spermidine; Spermine | 1979 |
Inhibition of phorbol ester-induced polyamine accumulation in mouse epidermis by anti-inflammatory steroid.
Topics: Animals; Carboxy-Lyases; Female; Fluocinolone Acetonide; Mice; Ornithine Decarboxylase; Phorbols; Polyamines; Putrescine; Skin; Spermidine; Spermine; Tetradecanoylphorbol Acetate | 1979 |
Effect of inhibitors on ornithine and adenosylmethionine decarboxylases on the synthesis of deoxyribonucleic acid in Ehrlich ascites cells in vivo.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Diamines; DNA, Neoplasm; Female; Guanidines; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine; Time Factors | 1979 |
The utilization of an inhibitor of spermidine and spermine synthesis as a tool for the study of the determination of cavitation in the preimplantation mouse embryo.
Topics: Animals; Blastocyst; Cell Count; Cell Division; DNA; Dose-Response Relationship, Drug; Guanidines; Mice; Mitoguazone; RNA; Spermidine; Spermine | 1979 |
Synthesis and content of polyamines in bloodstream Trypanosma brucei.
Topics: Amino Acids; Animals; Arginine; Blood; Methionine; Ornithine; Polyamines; Putrescine; Rats; Spermidine; Spermine; Trypanosoma brucei brucei | 1979 |
High-performance liquid chromatographic determination of free and total polyamines in human serum as fluorescamine derivatives.
Topics: Adult; Cadaverine; Chromatography, High Pressure Liquid; Fluorescamine; Humans; Polyamines; Putrescine; Spermidine; Spermine | 1979 |
Inhibition of blood coagulation factor XIIIa-mediated cross-linking between fibronectin and collagen by polyamines.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Collagen; Cross-Linking Reagents; Factor XIII; Fibronectins; Humans; Rats; Spermidine; Spermine | 1979 |
Binding of the Cain quinolinium, NSC 113089, to rat tissue lipid extracts.
Topics: Animals; Binding Sites; Calcium; Female; Kidney; Kinetics; Lipid Metabolism; Liver; Male; Muscles; Myocardium; Quinolinium Compounds; Rats; Spermidine; Spermine | 1979 |
[Clinical significance of polyamine measurement in laryngeal tumors].
Topics: Cadaverine; Chromatography, Gas; Humans; Laryngeal Neoplasms; Polyamines; Putrescine; Spermidine; Spermine | 1978 |
Polyamine biosynthesis and DNA synthesis in cultured mammary gland explants from virgin mice.
Topics: Adenosylmethionine Decarboxylase; Animals; DNA; Female; Insulin; Mammary Glands, Animal; Mice; Mitoguazone; Organ Culture Techniques; Ornithine Decarboxylase; Putrescine; Spermidine; Spermidine Synthase; Spermine | 1978 |
Role of polyamines in cytokinesis of mammalian cells.
Topics: Cell Division; Cell Line; Cytoskeleton; Mitoguazone; Ornithine; Putrescine; Spermidine; Spermine | 1979 |
RNA synthesis in isolated nuclei of the dinoflagellate Crypthecodinium cohnii.
Topics: Amanitins; Ammonium Sulfate; Animals; Biological Evolution; Cations, Divalent; Cell Nucleus; Cell-Free System; Dinoflagellida; DNA-Directed RNA Polymerases; RNA; Spermidine; Spermine; Templates, Genetic | 1979 |
Regulation of the ornithine decarboxylase activity by concomitant translational and transcriptional control during early embryonic development.
Topics: Animals; Carboxy-Lyases; Embryo, Nonmammalian; Gastrula; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polychaeta; Protein Biosynthesis; Putrescine; Spermidine; Spermine; Transcription, Genetic | 1979 |
Effect of polyamines and their oxidized derivatives on the metabolism of rat epididymal spermatozoa.
Topics: Adenosine Triphosphate; Animals; Cadaverine; Calcium; Epididymis; Fructose; Glucose; Histamine; Male; Ornithine; Putrescine; Rats; Spermatozoa; Spermidine; Spermine | 1978 |
Serum polyamine alterations in surgical patients with colorectal carcinoma.
Topics: Colonic Diseases; Colonic Neoplasms; Female; Humans; Male; Middle Aged; Polyamines; Putrescine; Rectal Neoplasms; Spermidine; Spermine; Time Factors | 1977 |
Ornithine decarboxylase antizyme is a normal component of uninduced H-35 cells and rat liver.
Topics: Animals; Carboxy-Lyases; Cell Line; Female; Liver; Ornithine Decarboxylase Inhibitors; Proteins; Putrescine; Rats; Spermidine; Spermine; Subcellular Fractions | 1977 |
Effect of age of rat on polyamine content of liver nuclei [proceedings].
Topics: Aging; Animals; Cell Nucleus; Liver; Polyamines; Rats; Spermidine; Spermine | 1977 |
[Electrophoretic characterization of a diamino oxidase with elevated affinity for spermidine and spermine].
Topics: Biochemical Phenomena; Biochemistry; Oxidoreductases Acting on CH-NH Group Donors; Spermidine; Spermine | 1977 |
Polyamine compartmentalization in various human disease states.
Topics: Blood Platelets; Disease; Erythrocytes; Humans; Monocytes; Neutrophils; Polyamines; Putrescine; Spermidine; Spermine | 1978 |
Polyamine metabolism in regenerating livers from normal and hypocalcemic rats.
Topics: Adenosylmethionine Decarboxylase; Animals; DNA; Hypocalcemia; Liver; Liver Regeneration; Male; Mitosis; Ornithine Decarboxylase; Putrescine; Rats; Spermidine; Spermine; Time Factors | 1978 |
Inhibition of spermidine and spermine synthesis leads to growth arrest of rat embryo fibroblasts in G1.
Topics: Adenosylmethionine Decarboxylase; Cell Cycle; Cell Division; Cell Line; DNA; Mitoguazone; Putrescine; Spermidine; Spermine | 1978 |
High-speed liquid chromatographic determination of putrescine, spermidine and spermine in human urine.
Topics: Chromatography, High Pressure Liquid; Humans; Methods; Putrescine; Spermidine; Spermine | 1978 |
Simplified micro-method for the quantitative analysis of putrescine, spermidine and spermine in urine.
Topics: Chromatography, Thin Layer; Dansyl Compounds; Female; Humans; Microchemistry; Pregnancy; Putrescine; Spectrometry, Fluorescence; Spermidine; Spermine | 1978 |
Changes in concentrations of polyamines and gamma-aminobutyric acid and their formation in chick embryo brain during development.
Topics: Aminobutyrates; Animals; Brain; Carbon Radioisotopes; Chick Embryo; Chromatography, Thin Layer; Electrophoresis, Paper; gamma-Aminobutyric Acid; In Vitro Techniques; Spermidine; Spermine | 1978 |
[Spermine and spermidine polyamines in the brain and liver of rats under hyperoxic action].
Topics: Animals; Brain; Hyperbaric Oxygenation; Liver; Male; Oxygen; Rats; Seizures; Spermidine; Spermine; Time Factors | 1978 |
Polyamine metabolism in BHK21/C13 cells. Loss of spermidine from cells following transfer to serum-depleted medium.
Topics: Blood; Cell Division; Cell Line; Cell Survival; Culture Media; DNA; Putrescine; Spermidine; Spermine | 1978 |
Urinary metabolites of polyamines in rats.
Topics: Animals; Male; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1978 |
Inhibition of phospholipase A2 and phospholipase C by polyamines.
Topics: Animals; Cattle; Clostridium; Elapid Venoms; Kinetics; Lectins; Membrane Lipids; Mitochondria, Heart; Phospholipases; Putrescine; Spermidine; Spermine | 1978 |
Translation of PVX RNA in vitro by wheat germ. I. Characterization of the reaction and product size.
Topics: Cell-Free System; Molecular Weight; Peptide Biosynthesis; Plant Viruses; Protein Biosynthesis; RNA, Messenger; RNA, Viral; Spermidine; Spermine | 1978 |
Accumulation of spermidine and spermine in Ehrlich ascites tumor cells during plateau phase growth. A function of an increased fraction of G2 phase cells and polyploid cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Carcinoma, Ehrlich Tumor; Cell Count; Cell Cycle; Cell Division; Diploidy; DNA, Neoplasm; Male; Mice; Neoplasm Transplantation; Ornithine Decarboxylase; Polyploidy; Spermidine; Spermine | 1978 |
[Polyamines and RNA in myocardial hypoxia and anoxia (author's transl)].
Topics: Adenosylmethionine Decarboxylase; Animals; Hypoxia; Microsomes; Mitochondria, Heart; Myocardial Infarction; Myocardium; Ornithine Decarboxylase; Polyamines; Rabbits; RNA; Spermidine; Spermine | 1978 |
Sensitive fluorimetric method for the determination of putrescine, spermidine and spermine by high-performance liquid chromatography and its application to human blood.
Topics: Chromatography, High Pressure Liquid; Dansyl Compounds; Erythrocytes; Humans; Neoplasms; Putrescine; Spectrometry, Fluorescence; Spermidine; Spermine | 1978 |
Effects of infection with Coxiella burnetii on synthesis of RNA in L cells.
Topics: Animals; DNA-Directed RNA Polymerases; Guinea Pigs; L Cells; Lipopolysaccharides; Putrescine; Q Fever; Rifampin; RNA; Spermidine; Spermine | 1978 |
Clearance of the polyamines from the perfused cerebroventricular system of the rabbit.
Topics: Animals; Cerebral Ventricles; Kinetics; Male; Perfusion; Rabbits; Spermidine; Spermine | 1978 |
Polyamines and nucleic acids in the mouse kidney induced to growth by testosterone propionate.
Topics: Adenosylmethionine Decarboxylase; Animals; Castration; DNA; Kidney; Male; Mice; Organ Size; Ornithine Decarboxylase; Polyamines; Proteins; Putrescine; RNA; Spermidine; Spermine; Testosterone | 1978 |
Automated chromatographic analysis of human placenta polyamines..
Topics: Chromatography, Gas; Female; Gestational Age; Humans; Mass Spectrometry; Placenta; Polyamines; Pregnancy; Putrescine; Spermidine; Spermine | 1978 |
Anti-proliferative properties of DL-alpha-difluoromethyl ornithine in cultured cells. A consequence of the irreversible inhibition of ornithine decarboxylase.
Topics: Carboxy-Lyases; Cell Division; Cell Line; Kinetics; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine | 1978 |
Purification of spermine synthase from bovine brain by spermine-Sepharose affinity chromatography.
Topics: Animals; Brain; Cattle; Chromatography, Affinity; Chromatography, Agarose; Ligands; Spermidine; Spermine; Spermine Synthase; Transferases | 1978 |
Biochemical markers of cultured human prostatic epithelium.
Topics: Autoanalysis; Carcinoembryonic Antigen; Cells, Cultured; Chromatography, Ion Exchange; Epithelium; Humans; Male; Microscopy, Electron; Polyamines; Prostate; Putrescine; Radioimmunoassay; Spermidine; Spermine | 1978 |
Apparent cooperativity of cation binding to protonated transfer RNA measured by quantitation of released protons.
Topics: Chemical Phenomena; Chemistry; Kinetics; Magnesium; Mathematics; RNA, Transfer; Spermidine; Spermine | 1978 |
Polyamine induced changes in the ADP-ribosylation of nuclear proteins from rat liver.
Topics: Adenosine Diphosphate Sugars; Animals; Cell Nucleus; Chromosomal Proteins, Non-Histone; Histones; Isoelectric Point; Liver; Male; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Rats; Ribose; Spermidine; Spermine | 1978 |
Relationship between polyamine contents and protease activity in the rat submaxillary gland.
Topics: Adenosylmethionine Decarboxylase; Animals; Male; Mitoguazone; Ornithine Decarboxylase; Peptide Hydrolases; Polyamines; Putrescine; Rats; Spermidine; Spermine; Submandibular Gland; Testis; Testosterone | 1978 |
Analysis of spermidine and spermine in rat liver. Effect of hypophysectomy on polyamine concentrations.
Topics: Aging; Animals; Chromatography, Ion Exchange; Hypophysectomy; Liver; Male; Rats; Spermidine; Spermine | 1978 |
Concentrations of polyamines in renal cell carcinoma.
Topics: Adenocarcinoma; Adult; Aged; DNA, Neoplasm; Female; Humans; Kidney; Kidney Neoplasms; Male; Middle Aged; Neoplasm Proteins; Polyamines; RNA, Neoplasm; Spermidine; Spermine | 1978 |
The modulation of the induction of ornithine decarboxylase by spermine, spermidine and diamines.
Topics: Carboxy-Lyases; Cell Line; Diamines; Dose-Response Relationship, Drug; Enzyme Induction; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine | 1978 |
Excretion of spermidine from BHK-21/C13 cells exposed to 6-thioguanosine.
Topics: Cell Division; Cells, Cultured; Guanosine; Putrescine; Spermidine; Spermine; Thionucleosides | 1978 |
Spermine and spermidine, modulators of the cell surface enzyme adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adult; Cell Membrane; Cells, Cultured; Child; Child, Preschool; Cystic Fibrosis; Fibroblasts; Humans; In Vitro Techniques; Infant, Newborn; Spermidine; Spermine | 1978 |
Liver ornithine decarboxylase during phenobarbital promotion of nitrosamine carcinogenesis.
Topics: Animals; Carboxy-Lyases; Diethylnitrosamine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Ornithine Decarboxylase; Phenobarbital; Rats; Spermidine; Spermine | 1978 |
Effect of polyamines and divalent cations on histone H1-poly(adenosine diphosphate ribose) complex formation.
Topics: Calcium; Dose-Response Relationship, Drug; Histones; Magnesium; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Polyamines; Putrescine; Spermidine; Spermine | 1978 |
Ornithine decarboxylase and polyamines in the resumption of cycling by diluted and reoxygenated mammalian cells.
Topics: Carboxy-Lyases; Cell Cycle; Cell Line; DNA; Ornithine Decarboxylase; Oxygen; Polyamines; Protein Biosynthesis; Putrescine; Spermidine; Spermine | 1978 |
Glucocorticoid inhibits elevated polyamine biosynthesis in psoriasis.
Topics: Epidermis; Glucocorticoids; Humans; Polyamines; Psoriasis; Putrescine; Pyruvaldehyde; Spermidine; Spermine | 1978 |
Polyamines and ornithine decarboxylase activity in the developing rat retina.
Topics: Aging; Animals; Animals, Newborn; Carboxy-Lyases; Eye Proteins; Female; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Retina; Spermidine; Spermine | 1978 |
Diminished excretion of polyamines from BHK-21/C13 cells exposed to methylglyoxal bis(guanylhydrazone).
Topics: Cell Division; Cell Line; Guanidines; Mitoguazone; Polyamines; Putrescine; Spermidine; Spermine | 1978 |
Polyamine distribution in eukaryotes: occurrence of sym-norm-spermidine and sym-nor-spermine in arthropods.
Topics: Animals; Arthropods; Cells; Eukaryotic Cells; Species Specificity; Spermidine; Spermine | 1978 |
Effect of malnutrition and rehabilitation on the metabolism of polyamines in rat liver.
Topics: Adenosylmethionine Decarboxylase; Animals; Caseins; Dietary Proteins; Liver; Male; Nucleic Acids; Ornithine Decarboxylase; Orotic Acid; Polyamines; Protein Deficiency; Putrescine; Rats; Spermidine; Spermine | 1978 |
A simple and sensitive method of analysis for histamine, putrescine, and polyamines without the use of an amino acid analyzer.
Topics: Animals; Chromatography, Ion Exchange; Fluorescamine; Histamine; Humans; Mercaptoethanol; o-Phthalaldehyde; Organ Specificity; Polyamines; Putrescine; Rats; Spermidine; Spermine; Trinitrobenzenesulfonic Acid | 1978 |
Kinetics of polyamine synthesis and turnover in mouse fibroblasts.
Topics: Animals; DNA; Fibroblasts; In Vitro Techniques; Kinetics; Mice; Polyamines; Putrescine; Spermidine; Spermine | 1978 |
Cellular polyamine depletion reduces DNA synthesis in isolated lymphocyte nuclei.
Topics: Animals; Cattle; Cell Nucleus; DNA; DNA Replication; Guanidines; Kinetics; Lymphocytes; Mitoguazone; Ornithine; Putrescine; Spermidine; Spermine | 1978 |
Polyamine stimulation of phosphorylation of nonhistone acidic protein in nuclei and nucleoli from Physarum polycephalum.
Topics: Cell Nucleolus; Cell Nucleus; Chromosomal Proteins, Non-Histone; Kinetics; Molecular Weight; Phosphorylation; Physarum; Polyamines; Putrescine; Spermidine; Spermine | 1978 |
Polyamines in amniotic fluid, plasma, and urine during normal pregnancy.
Topics: Amniotic Fluid; Female; Gestational Age; Humans; Polyamines; Pregnancy; Putrescine; Spermidine; Spermine | 1978 |
Enhancement of thermal killing by polyamines. I. Survival of Chinese hamster cells.
Topics: Animals; Cadaverine; Cell Survival; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Fibroblasts; Hot Temperature; Polyamines; Putrescine; Spermidine; Spermine; Time Factors | 1978 |
Enhancement of thermal killing by polyamines. II. Uptake and metabolism of exogenous polyamines in hyperthermic Chinese hamster cells.
Topics: Animals; Cadaverine; Cells, Cultured; Cricetinae; DNA; Fibroblasts; Hot Temperature; Polyamines; Protein Biosynthesis; Putrescine; RNA; Spermidine; Spermine | 1978 |
Interconversion of aliphatic polyamines in isoproterenol-stimulated mouse parotid glands.
Topics: Animals; Cell Division; Isoproterenol; Kidney; Liver; Male; Mice; Organ Specificity; Ornithine Decarboxylase; Parotid Gland; Putrescine; Spermidine; Spermine | 1978 |
Polyamine biosynthesis in rabbit perfused heart under various degrees of oxygen tension.
Topics: Adenosylmethionine Decarboxylase; Animals; Hypoxia; Myocardium; Ornithine Decarboxylase; Polyamines; Putrescine; Rabbits; Spermidine; Spermine | 1978 |
Polyamine levels in human semen of unfertile patients: effect of S-adenosylmethionine.
Topics: Humans; Infertility, Male; Male; S-Adenosylmethionine; Semen; Sperm Motility; Spermidine; Spermine | 1978 |
Formation of CO2 from the carboxyl group of S-adenosylmethionine by liver membrane-associated enzymes involves the demethylation-transsulphuration pathway.
Topics: Animals; Carbon Dioxide; Cell Membrane; Cytosol; Decarboxylation; Liver; Rats; S-Adenosylmethionine; Spermidine; Spermine; Subcellular Fractions | 1978 |
Determination of polyamines by liquid chromatography and precolumn labelling for fluorescence detection.
Topics: Chromatography, Liquid; Dansyl Compounds; Polyamines; Putrescine; Spectrometry, Fluorescence; Spermidine; Spermine | 1978 |
Control of ornithine decarboxylase activity in Physarum by polyamines.
Topics: Buffers; Carboxy-Lyases; Dithiothreitol; Ornithine Decarboxylase Inhibitors; Physarum; Polyamines; Putrescine; Spermidine; Spermine | 1978 |
Polyamine metabolism and DNA synthesis in regenerating rat liver.
Topics: Amino Acids; Animals; Cadaverine; Diamines; DNA; Hydrazines; Kinetics; Liver; Liver Regeneration; Male; Putrescine; Rats; Spermidine; Spermine | 1978 |
Increased formation of diamines and polyamines in the pregnant rat.
Topics: Animals; Cadaverine; Diamines; Female; Guanidines; Histamine; Hydrolysis; Methylhistamines; Polyamines; Pregnancy; Pregnancy, Animal; Putrescine; Rats; Spermidine; Spermine | 1978 |
Peptides isolated from Enterobacter nuclease as potential polyamine binding sites.
Topics: Amino Acids; Binding Sites; Chromatography, Affinity; Enterobacteriaceae; Escherichia coli; Kinetics; Peptide Fragments; Poly C; Polyamines; Protein Binding; Putrescine; Ribonucleases; Spermidine; Spermine | 1976 |
Aminoacyl transfer RNA formation. Binding of cations to transfer RNA and its role in aminoacyl transfer RNA formation.
Topics: Binding Sites; Escherichia coli; Isoleucine; Isoleucine-tRNA Ligase; Magnesium; Polyamines; RNA, Transfer; Spermidine; Spermine; Transfer RNA Aminoacylation | 1976 |
Polyamine stimulation and cation requirements of rabbit liver tRNA nucleotidyltransferase.
Topics: Animals; Cadaverine; Enzyme Activation; Escherichia coli; Kinetics; Liver; Magnesium; Osmolar Concentration; Polyamines; Potassium Chloride; Putrescine; Rabbits; RNA Nucleotidyltransferases; RNA, Transfer; Spermidine; Spermine | 1976 |
Synthesis of polyamines in the germinating conidia of Aspergillus nidulans.
Topics: Aspergillus nidulans; Kinetics; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Spores, Fungal | 1976 |
The effects of putrescine, spermidine, and spermine on the growth of a polyamine-requiring mutant of Aspergillus nidulans.
Topics: Aspergillus nidulans; Cell Division; Mutation; Polyamines; Putrescine; Spermidine; Spermine | 1976 |
[Prevention of 3,4-benzpyrene carcinogenesis by naturally occurring and synthetic compounds].
Topics: Aconitic Acid; Animals; Antineoplastic Agents; Benzopyrenes; Cadaverine; Carcinogens; Cysteine; Dicarboxylic Acids; Dithiothreitol; Ethanolamines; Female; Fumarates; Maleates; Mice; Neoplasms, Experimental; Putrescine; Spermidine; Spermine; Sulfhydryl Compounds; Tricarboxylic Acids | 1975 |
Polyamine metabolism in the brain and liver of the developing monkey.
Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Brain; Female; Haplorhini; Liver; Macaca mulatta; Male; Occipital Lobe; Ornithine Decarboxylase; Pregnancy; Putrescine; Spermidine; Spermidine Synthase; Spermine | 1975 |
Thyroid function and polyamines. II. Thyrotropin stimulation of polyamine biosynthesis in the rat thyroid.
Topics: Adenosylmethionine Decarboxylase; Animals; DNA; Dose-Response Relationship, Drug; Male; Methylthiouracil; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; RNA; Spermidine; Spermine; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Time Factors | 1975 |
Polyamines in bovine epididymal spermatozoa.
Topics: Amine Oxidase (Copper-Containing); Animals; Cattle; Epididymis; Histamine; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Spermatozoa; Spermidine; Spermine | 1975 |
Cell-free, protein-synthesizing system of photosynthetic and heterotrophic Rhodospirillum rubrum.
Topics: Amino Acids; Bacterial Proteins; Biotin; Cell-Free System; Chloramphenicol; Kinetics; Magnesium; Peptide Hydrolases; Phenylmethylsulfonyl Fluoride; Photosynthesis; Poly U; Potassium Chloride; Puromycin; Putrescine; Rhodospirillum rubrum; RNA, Bacterial; RNA, Messenger; Spermidine; Spermine; Templates, Genetic | 1976 |
The effect of polyamines on the synthesis of ribonucleic acid by Drosophila melanogaster larvae.
Topics: Animals; Cadaverine; Drosophila melanogaster; Ethylenediamines; Larva; Methionine; Polyamines; Putrescine; RNA; Spermidine; Spermine; Time Factors; Uridine | 1976 |
The synthesis and accumulation of polyamines in reproductive organs of the rat during pregnancy.
Topics: Amine Oxidase (Copper-Containing); Animals; Female; Organ Specificity; Ornithine Decarboxylase; Ovary; Placenta; Pregnancy; Pregnancy, Animal; Putrescine; Rats; Spermidine; Spermine; Time Factors; Uterus | 1976 |
Purification of human spleen ribonuclease by immunoabsorption. Similarity of the enzyme with human liver ribonuclease.
Topics: Calcium; Chromatography, Affinity; Cross Reactions; Humans; Immunodiffusion; Liver; Macromolecular Substances; Molecular Weight; Putrescine; Ribonucleases; Spermidine; Spermine; Spleen | 1976 |
Polyamines as markers of response and disease activity in cancer chemotherapy.
Topics: Antineoplastic Agents; Female; Humans; Male; Neoplasms; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Polyamine-stimulated growth of cultured rat urinary bladder epithelial cells.
Topics: Animals; Cell Division; Cells, Cultured; Epithelial Cells; Epithelium; Male; Polyamines; Putrescine; Rats; Spermidine; Spermine; Urinary Bladder | 1977 |
Conjugation of radiolabeled polyamines in the rat.
Topics: Animals; Hepatectomy; Kidney; Liver; Male; Metabolic Clearance Rate; Neoplasms; Nephrectomy; Putrescine; Rats; Spermidine; Spermine | 1977 |
Carbon-11-labeled methylated polyamine analogs: uptake in prostate and tumor in animal models.
Topics: Animals; Carbon Radioisotopes; Dogs; Male; Melanoma; Methylation; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Polyamines; Prostatic Neoplasms; Putrescine; Radionuclide Imaging; Rats; Spermidine; Spermine; Tomography | 1977 |
The relationship between polyamine accumulation and DNA replication in synchronized Chinese hamster ovary cells after heat shock.
Topics: Biological Transport; Cell Division; Cell Membrane; Cells, Cultured; DNA; DNA Replication; Hot Temperature; Kinetics; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Insulin-like effects of polyamines in fat cells. Mediation by H2O2 formation.
Topics: Adipose Tissue; Animals; Catalase; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Male; Nonsuppressible Insulin-Like Activity; Polyamines; Rats; Serum Albumin, Bovine; Spermidine; Spermine | 1977 |
Polyamines contained by two densonucleosis viruses.
Topics: Animals; Insect Viruses; Insecta; Parvoviridae; Polyamines; Putrescine; Spermidine; Spermine; Viral Proteins | 1977 |
Inhibitors of polyamine biosynthesis. 4. Effects of alpha-methyl-(+/-)-ornithine and methylglyoxal bis(guanylhydrazone) on growth and polyamine content of L1210 leukemic cells of mice.
Topics: Animals; Cell Division; Cells, Cultured; DNA, Neoplasm; Guanidines; Leukemia L1210; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Effect of thyrotropin on ornithine decarboxylase and of polyamines on RNA polymerase in the thyroid.
Topics: Animals; Carboxy-Lyases; Cattle; DNA-Directed RNA Polymerases; Dogs; In Vitro Techniques; Ornithine Decarboxylase; Polyamines; Putrescine; RNA Polymerase I; RNA Polymerase II; Spermidine; Spermine; Thyroid Gland; Thyrotropin | 1977 |
DNA synthesis in HeLa cells and isolated nuclei after treatment with an inhibitor of spermidine synthesis, methyl glyoxal bis(guanylhydrazone).
Topics: Cell Nucleus; DNA Replication; Guanidines; HeLa Cells; Kinetics; Mitoguazone; Protein Biosynthesis; Putrescine; Spermidine; Spermine | 1977 |
[Synthesis of isomeric and homologous spermidine and spermine derivatives and their identification by mass spectrometry (author's transl)].
Topics: Mass Spectrometry; Methods; Spermidine; Spermine | 1977 |
Rapid chromatographic method to determine polyamines in urine and whole blood.
Topics: Autoanalysis; Chromatography, Ion Exchange; Humans; Hydrolysis; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Acetylation of spermidine and spermine by rat liver and kidney chromatin.
Topics: Acetyltransferases; Animals; Chromatin; Kidney; Kinetics; Liver; Male; Organ Specificity; Putrescine; Rats; Spermidine; Spermine | 1977 |
Putrescine biosynthesis in mammalial cells: essential for DNA synthesis but not for mitosis.
Topics: Cell Division; Cell Line; Diamines; DNA Replication; Kinetics; Mitosis; Putrescine; Spermidine; Spermine; Time Factors | 1977 |
Polyamines and their biosynthetic decarboxylases in various tissues of the young rat during recovery from undernutrition.
Topics: Adenosylmethionine Decarboxylase; Animals; Female; Liver; Male; Muscles; Nutrition Disorders; Organ Size; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Sex Factors; Spermidine; Spermine; Spleen | 1977 |
Deoxyribonucleic acid and polyamine synthesis in rat ventral prostrate. Effects of age of the intact rat and androgen stimulation of the castrated rat with testosterone, 5 alpha-dihydrotestosterone and 5 alpha-androstane-3 beta, 17 beta-diol.
Topics: Age Factors; Androgens; Animals; Castration; DNA; Male; Ornithine Decarboxylase; Polyamines; Prostate; Putrescine; Rats; Spermidine; Spermine | 1977 |
Involvement of polyamines in the progestin-induced stimulation of endometrial glycogen synthesis during organ culture.
Topics: Adenosylmethionine Decarboxylase; Animals; Endometrium; Female; Glycogen; Guinea Pigs; Progesterone; Putrescine; Spermidine; Spermine | 1977 |
Metabolism of putrescine in the central nervous system.
Topics: Animals; Brain; Carnosine; gamma-Aminobutyric Acid; Glutamates; Male; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1977 |
Cerebrospinal fluid polyamine monitoring in central nervous system leukemia.
Topics: Adolescent; Cerebrospinal Fluid Proteins; Child; Child, Preschool; Chromatography, High Pressure Liquid; Erythrocytes; Glucose; Humans; Leukemia, Lymphoid; Leukocytes; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Brain regional spermidine and spermine levels in relation to RNA and DNA in aging rat brain.
Topics: Aging; Animals; Brain; Brain Chemistry; Cerebral Cortex; Corpus Striatum; DNA; Hippocampus; Hypothalamus; Male; Medulla Oblongata; Mesencephalon; Methods; Nerve Tissue Proteins; Organ Size; Pons; Rats; RNA; Spermidine; Spermine | 1977 |
Possible role of polyamines in the neurotrophic regulation of muscle acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Culture Techniques; Hindlimb; Male; Muscles; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1977 |
Polyamine levels in normal human serum. Comparison of analytical methods.
Topics: Chromatography, Gas; Chromatography, Ion Exchange; Cross Reactions; Evaluation Studies as Topic; Humans; Mass Spectrometry; Putrescine; Radioimmunoassay; Spermidine; Spermine | 1977 |
The role of polyamines in cell-free protein synthesis in the wheat-germ system.
Topics: Cell-Free System; Globins; Kinetics; Magnesium; Peptide Chain Elongation, Translational; Plant Proteins; Plants; Polyribosomes; Protein Biosynthesis; RNA, Messenger; RNA, Viral; Spermidine; Spermine; Tobacco Mosaic Virus; Triticum | 1977 |
Regulation of messenger RNA by a ribonucleic factor in the presence of polyamines.
Topics: Animals; Hemoglobins; Peptide Initiation Factors; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA; RNA, Messenger; Spectrophotometry, Ultraviolet; Spermidine; Spermine | 1977 |
Polyamines as markers of response to chemotherapy of cancer.
Topics: Humans; Neoplasms; Putrescine; Spermidine; Spermine | 1977 |
Quantitative analysis of biological marker synthesis in tumor cell cycle.
Topics: Cell Division; Cells, Cultured; DNA; Kinetics; Models, Biological; Neoplasms; Spermidine; Spermine; Time Factors | 1977 |
Polyamines of the human brain during normal fetal and postnatal growth and during postnatal malnutrition.
Topics: Aging; Brain; Brain Stem; Cerebellum; Child, Preschool; Female; Fetus; Gestational Age; Humans; Infant; Infant, Newborn; Nutrition Disorders; Polyamines; Pregnancy; Putrescine; Spermidine; Spermine | 1977 |
A new method for qualitative and quantitative determination of di- and polyamines in animal tissues by gas-liquid chromatography.
Topics: Amines; Animals; Brain Chemistry; Cadaverine; Chromatography, Gas; Liver; Male; Organ Specificity; Pancreas; Polyamines; Prostate; Putrescine; Rats; Spermidine; Spermine; Testis | 1977 |
Thermal inactivation of a Citrobacter ribonuclease: influence of polyamines and ionic strength.
Topics: Calorimetry; Citrobacter; Enterobacteriaceae; Hot Temperature; Mathematics; Osmolar Concentration; Polyamines; Protein Denaturation; Ribonucleases; Spermidine; Spermine; Structure-Activity Relationship; Thermodynamics | 1977 |
Inhibition of the synthesis of polyamines and DNA in activated lymphocytes by a combination of alpha-methylornithine and methylglyoxal bis(guanylhydrazone).
Topics: Animals; Cattle; Cell Division; Concanavalin A; DNA; DNA Replication; Drug Interactions; Guanidines; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Mitoguazone; Ornithine; Polyamines; Protein Biosynthesis; Putrescine; RNA; Spermidine; Spermine | 1977 |
Polyamines in trypanosomatids.
Topics: Animals; Eukaryota; Putrescine; Spermidine; Spermine; Trypanosoma; Trypanosoma brucei brucei | 1977 |
Gas chromatography mass spectrometry analysis of polyamines using deuterated analogs as internal standards.
Topics: Cadaverine; Chromatography, Gas; Deuterium; Mass Spectrometry; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Ornithine decarboxylase activity and polyamines in relation to aging of human fibroblasts.
Topics: Carboxy-Lyases; Cell Division; Cell Line; Cell Survival; Guanidines; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Polyamine effects on succinate-linked and alphaketoglutarate- linked rat liver mitochondrial respiration.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Ketoglutaric Acids; Magnesium; Male; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Rats; Spermidine; Spermine; Succinates | 1977 |
Inhibition of indolethylamine-N-methyltransferase by aliphatic diamines.
Topics: Animals; Diamines; Kinetics; Lung; Male; Methyltransferases; Molecular Weight; Rabbits; Spermidine; Spermine; Tryptamines | 1977 |
Effect of polyamines on the activity of acrosin and the activation of proacrosin.
Topics: Acrosin; Animals; Cadaverine; Calcium; Endopeptidases; Enzyme Activation; Enzyme Precursors; Esterases; Humans; Male; Polyamines; Putrescine; Semen; Spermidine; Spermine; Swine; Trypsin | 1977 |
The role of putrescine in cell proliferation of the skin of mice induced by ethylphenylpropriolate.
Topics: Adenosylmethionine Decarboxylase; Alkynes; Animals; Cell Division; Diamines; DNA; Epidermal Cells; Male; Ornithine; Ornithine Decarboxylase; Propionates; Putrescine; Skin; Spermidine; Spermine | 1977 |
Release of polyamines from growing and serum-deprived BHK-21/C13 cells [proceedings].
Topics: Blood; Cell Division; Cell Line; Culture Media; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Effects of spermine and spermidine on single brain stem neurones.
Topics: Action Potentials; Animals; Brain Stem; Cats; Decerebrate State; Electric Stimulation; Neurons; Rats; Spermidine; Spermine | 1977 |
Ornithine decarboxylase induction and DNA synthesis in hamster embryo cell cultures treated with tumor-promoting phorbol diesters.
Topics: Carboxy-Lyases; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Enzyme Induction; Ornithine Decarboxylase; Phorbols; Putrescine; Spermidine; Spermine; Tetradecanoylphorbol Acetate | 1977 |
Polyamine biosynthesis and accumulation during the G1 to S phase transition.
Topics: Adenosylmethionine Decarboxylase; Cell Cycle; Cell Line; Hot Temperature; Interphase; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine | 1977 |
Preliminary longitudinal studies of serum polyamines in patients with colorectal carcinoma.
Topics: Adenocarcinoma; Colonic Neoplasms; Humans; Intestinal Polyps; Longitudinal Studies; Middle Aged; Prognosis; Putrescine; Rectal Neoplasms; Sigmoid Neoplasms; Spermidine; Spermine | 1977 |
Effect of methylglyoxal-bis (guanylhydrazone), an inhibitor of spermidine and spermine synthesis, on cell cycle traverse.
Topics: Animals; Brain Neoplasms; Cell Cycle; Cells, Cultured; Guanidines; Mitoguazone; Putrescine; Rats; Spermidine; Spermine | 1977 |
Pharmacological actions of intracerebrally administered polyamines in mice.
Topics: Animals; Body Temperature; Body Weight; Brain; Injections; Male; Mice; Motor Activity; Sleep; Spermidine; Spermine; Time Factors | 1977 |
The transcriptase complex of the paramyxovirus SV5.
Topics: Dactinomycin; DNA-Directed RNA Polymerases; Magnesium; Manganese; Molecular Weight; Paramyxoviridae; Peptides; Polyethylene Glycols; RNA, Viral; Spermidine; Spermine | 1977 |
Interactions between polyamines and nucleotides.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Chemical Phenomena; Chemistry; Deoxyribonucleotides; Kinetics; Mathematics; Polyamines; Putrescine; Ribonucleotides; Spermidine; Spermine | 1977 |
Kinetics of cell proliferation and polyamine synthesis during Ehrlich ascites tumor growth.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Division; Cell Survival; Kinetics; Male; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
The distribution and metabolism of putrescine, spermidine and spermine injected into the cerebral ventricles of rabbits.
Topics: Animals; Brain; Caudate Nucleus; Cerebral Cortex; Hypothalamus; Kinetics; Medulla Oblongata; Organ Specificity; Putrescine; Rabbits; Spermidine; Spermine | 1976 |
The effect of spermidine and spermine on proliferation in vitro of fibroblasts from normal and cystic fibrosis patients.
Topics: Cell Division; Cystic Fibrosis; Depression, Chemical; Fibroblasts; Humans; Spermidine; Spermine | 1976 |
The effect of polyamines on the thermostability of a cell free protein synthesizing system of an extreme thermophile.
Topics: Amino Acyl-tRNA Synthetases; Bacterial Proteins; Binding Sites; Cell-Free System; Cold Temperature; Gram-Negative Aerobic Bacteria; Hot Temperature; Phenylalanine; Polyamines; Ribosomes; RNA, Bacterial; RNA, Transfer; Spermidine; Spermine | 1976 |
Adenylate cyclases in physarum polycephalum: inhibition of a nuclear enzyme by polyamines.
Topics: Adenylyl Cyclases; Cell Nucleus; Kinetics; Myxomycetes; Physarum; Putrescine; Spermidine; Spermine | 1976 |
[Effect of polyamines on mitochondrial membranes: studies with fluorescent probes].
Topics: Animals; Cattle; Membranes; Mitochondria, Muscle; Myocardium; Polyamines; Putrescine; Spermidine; Spermine | 1976 |
[Interactions of polyamines with mitochondrial membranes: study with fluorescence polarization].
Topics: Animals; Cattle; Membranes; Mitochondria, Muscle; Myocardium; Polyamines; Putrescine; Spermidine; Spermine | 1976 |
The regulation of mouse liver ornithine decarboxylase by metabolites.
Topics: Animals; Binding, Competitive; Carboxy-Lyases; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Protein Binding; Putrescine; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Spermidine; Spermine | 1976 |
Distribution of spermidine and spermine in blood from cystic fibrosis patients and control subjects.
Topics: Cell Fractionation; Cell Separation; Citrates; Cystic Fibrosis; Heparin; Humans; Male; Polyamines; Spermidine; Spermine | 1976 |
Urinary polyamine levels in patients with localized malignancy.
Topics: Adolescent; Adult; Female; Gastrointestinal Neoplasms; Genital Neoplasms, Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Polyamines; Putrescine; Spermidine; Spermine; Urogenital Neoplasms | 1976 |
Organ culture of rodent prostate. Effects of polyamines and testosterone.
Topics: Animals; Culture Media; Epithelial Cells; Epithelium; Insulin; Male; Mice; Mice, Inbred BALB C; Models, Biological; Organ Culture Techniques; Polyamines; Prostate; Rats; Rats, Inbred F344; Spermidine; Spermine; Testosterone | 1976 |
Effects of polyamines on in vitro dna synthesis by DNA polymerases from calf thymus.
Topics: Animals; Cattle; DNA Nucleotidyltransferases; DNA Replication; Enzyme Activation; Kinetics; Magnesium; Manganese; Putrescine; Spermidine; Spermine; Structure-Activity Relationship; Thymus Gland | 1976 |
Polyamines and platelet aggregation.
Topics: Adenosine Diphosphate; Adolescent; Adult; Child; Epinephrine; Humans; Male; Platelet Aggregation; Psoriasis; Ristocetin; Spermidine; Spermine | 1976 |
Interconversion of putrescine, spermidine and spermine in goldfish and rat retina.
Topics: Animals; Goldfish; Putrescine; Rats; Retina; Spermidine; Spermine | 1976 |
Inhibition of the polyadenylation reaction in vitro by polyamines.
Topics: Animals; Kinetics; Liver; Nucleotidyltransferases; Polynucleotide Adenylyltransferase; Putrescine; Rats; Spermidine; Spermine | 1976 |
Polyamine synthesis in liver and kidney of flounder in response to methylmercury.
Topics: Adenosylmethionine Decarboxylase; Animals; Fishes; Kidney; Liver; Methylmercury Compounds; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1976 |
Biological activity of in vitro synthesised protein: binding of Semliki Forest virus capsid protein to the large ribosomal subunit.
Topics: Molecular Weight; Protein Biosynthesis; Ribosomes; RNA, Ribosomal; Seeds; Semliki forest virus; Spermidine; Spermine; Triticum; Viral Proteins | 1976 |
Determination of diamines and polyamines in tissues by high-pressure liquid chromatography.
Topics: Animals; Brain Chemistry; Cells, Cultured; Chromatography, High Pressure Liquid; Dansyl Compounds; Leukemia L1210; Liver; Male; Methods; Prostate; Putrescine; Rats; Spermidine; Spermine; Spleen | 1976 |
The effect of spermine and spermidine on the hydrolysis of acetylthiocholine in the presence of rat caudate nucleus homogenate or acetylcholinesterase from Electrophorus electricus.
Topics: Acetylcholinesterase; Acetylthiocholine; Animals; Caudate Nucleus; Choline; Cholinesterase Inhibitors; Electrophorus; Hydrolysis; Rats; Spermidine; Spermine; Stimulation, Chemical | 1976 |
Changes in ornithine decarboxylase activity in rat intestines during aging.
Topics: Aging; Animals; Brain; Carboxy-Lyases; Female; Intestines; Kinetics; Liver; Male; Nucleotides; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1976 |
Experimental revascularization of acute myocardial infarction. III: Correlation between the behaviour of the free nucleotide acid solubles and some aliphatic biogenic amines.
Topics: Animals; Dogs; Myocardial Infarction; Myocardial Revascularization; Myocardium; Nucleic Acids; Nucleotides; Spermidine; Spermine | 1976 |
Effects of spermidine, spermine and N-ethylmaleimide on the structure of the rat liver ribosome.
Topics: Animals; Ethylmaleimide; In Vitro Techniques; Liver; Rats; Ribonucleases; Ribosomes; Spermidine; Spermine | 1976 |
A possible involvement polyamines in the initiation of DNA synthesis by human WI-38 and mouse BALB/3T3 cells.
Topics: Cell Line; DNA; Guanidines; Mitoguazone; Polyamines; Putrescine; RNA; Spermidine; Spermine | 1976 |
Stimulatory effect of polyamines on polyphenylalanine synthesis on Mycobacterium smegmatis ribosomes.
Topics: Bacterial Proteins; Magnesium; Mycobacterium; Peptide Biosynthesis; Phenylalanine; Poly U; Polyamines; Putrescine; Ribosomes; Spermidine; Spermine | 1976 |
Inhibition of polyamine accumulation and deoxyribonucleic acid synthesis in regenerating rat liver.
Topics: Animals; Diamines; DNA; Enzyme Repression; Hepatectomy; Liver Regeneration; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; RNA; Spermidine; Spermine | 1976 |
Altered polyamine metabolism in the PRO/Re strain of inbred mice.
Topics: Adenosylmethionine Decarboxylase; Animals; Brain Chemistry; Enzyme Activation; Female; Kidney; Liver; Male; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1976 |
The effect of nandrolone, an anabolic steroid on putrescine metabolism in the mouse.
Topics: Animals; Carbon Dioxide; Kidney; Mice; Nandrolone; Putrescine; Spermidine; Spermine; Time Factors | 1976 |
Polyamines in malignant melanoma. Urinary excretion and disease progress.
Topics: Female; Humans; Male; Melanoma; Polyamines; Putrescine; Spermidine; Spermine | 1976 |
Interactions of chlorinated hydrocarbons with steroid hormones.
Topics: Animals; Castration; Chlordan; DDT; Dichlorodiphenyldichloroethane; Enzyme Induction; Female; Hormones; Liver; Male; Mixed Function Oxygenases; Ornithine Decarboxylase; Oxidoreductases; Receptors, Estrogen; Spermidine; Spermine; Steroids; Structure-Activity Relationship; Uterus | 1976 |
Starvation results in decreased initiation factor activity in rat skeletal muscle.
Topics: Animals; Aurintricarboxylic Acid; Creatine Kinase; Guanine Nucleotides; Guanosine Triphosphate; Kinetics; Magnesium; Methionine; Muscles; Myocardium; Organ Specificity; Peptide Initiation Factors; Phosphocreatine; Rats; RNA, Transfer; Spermidine; Spermine; Starvation | 1976 |
Polyamine distribution in cellular compartments of blood and in aging erythrocytes.
Topics: Adult; Blood Cells; Blood Platelets; Erythrocyte Aging; Erythrocytes; Female; Hemoglobins; Histocytochemistry; Humans; Male; Monocytes; Neutrophils; Polyamines; Putrescine; Reticulocytes; Spermidine; Spermine | 1976 |
Nitrosamines from the nitrosation of spermidine and spermine.
Topics: Chemical Phenomena; Chemistry; Chromatography, Gas; Mass Spectrometry; Nitrosamines; Spermidine; Spermine; Trifluoroacetic Acid | 1976 |
Effects of bilateral olfactory bulb ablations on the polyamine levels in rat brain.
Topics: Animals; Brain Chemistry; Male; Olfactory Bulb; Polyamines; Rats; Spermidine; Spermine | 1976 |
Polyamine-dependent deoxyribonuclease activity from rat-liver nuclei.
Topics: Animals; Calcium; Cell Nucleus; Deoxyribonucleases; Dialysis; DNA; Liver; Magnesium; Male; Polyamines; Rats; Spermidine; Spermine | 1976 |
Effect of DL-alpha-hydrazino-delta-aminovaleric acid, an inhibitor of ornithine decarboxylase, on polyamine metabolism and growth of mouse sarcoma-180.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cell Division; Depression, Chemical; DNA, Neoplasm; Hydrazines; Liver; Male; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; RNA, Neoplasm; Sarcoma 180; Spermidine; Spermine; Valine | 1976 |
An improved isolation procedure for the gas chromatographic analysis of urinary polyamines.
Topics: Cadaverine; Chromatography, Gas; Diamines; Humans; Putrescine; Spermidine; Spermine; Urinary Bladder Neoplasms | 1976 |
[Determination of blood polyamines in patients with brain tumor -with special reference to relationship between varieties of tumors and concentrations of blood spermidine and spermine (author's transl)].
Topics: Adult; Brain Neoplasms; Female; Glioma; Humans; Male; Meningioma; Middle Aged; Neurilemmoma; Pinealoma; Spermidine; Spermine | 1976 |
Increased cellular levels of spermidine or spermine are required for optimal DNA synthesis in lymphocytes activated by concanavalin A.
Topics: Animals; Cattle; Cell Division; Concanavalin A; DNA; Lymphocyte Activation; Lymphocytes; Mitoguazone; Mitosis; Spermidine; Spermine | 1975 |
Alpha-methyl ornithine, a potent competitive inhibitor of ornithine decarboxylase, blocks proliferation of rat hepatoma cells in culture.
Topics: Cell Division; Cells, Cultured; DNA Replication; Kinetics; Leucine; Ornithine; Putrescine; Spermidine; Spermine | 1976 |
[Polyamines in species of microorganisms of the intestinal group].
Topics: DNA, Bacterial; Enterobacteriaceae; Escherichia coli; Polyamines; Putrescine; RNA, Bacterial; Salmonella typhi; Shigella flexneri; Shigella sonnei; Spermidine; Spermine | 1975 |
Binding of transfer RNA to polyamines in preference to Mg-2+.
Topics: Binding Sites; Chromatography, Gel; Escherichia coli; Kinetics; Magnesium; RNA, Bacterial; RNA, Transfer; Spermidine; Spermine | 1975 |
The effect of spermine on transcription of mammalian chromatin by mammalian deoxyribonucleic acid-dependent ribonucleic acid polymerase.
Topics: Amanitins; Animals; Cell Nucleus; Chromatin; DNA; DNA-Directed RNA Polymerases; Escherichia coli; Liver; Male; Rats; RNA; Spermidine; Spermine; Transcription, Genetic | 1975 |
Effects of intercalating agents on the structure of the ribosome.
Topics: Acridines; Binding Sites; Escherichia coli; Ethidium; Kinetics; Magnesium; Ribonucleases; Ribosomes; Salmonella typhimurium; Spermidine; Spermine; Time Factors | 1975 |
Interaction of polyamines with fragments and whole molecules of yeast phenylalanine-specific transfer RNA.
Topics: Binding Sites; Dialysis; Magnesium; Manganese; Nucleic Acid Conformation; Phenylalanine; Polyamines; RNA, Transfer; Saccharomyces cerevisiae; Spermidine; Spermine | 1975 |
Polyamines in bacteriophage R17 and its RNA.
Topics: Carbon Radioisotopes; Cell-Free System; Coliphages; Escherichia coli; Magnesium; Phenylalanine; Poly U; Polyamines; Protein Biosynthesis; Putrescine; RNA Viruses; RNA, Messenger; RNA, Viral; Spermidine; Spermine; Valine; Viral Proteins | 1975 |
The binding of polyamines and of ethidium bromide to tRNA.
Topics: Binding Sites; Binding, Competitive; Chromatography, Gel; Dialysis; Escherichia coli; Ethidium; Magnesium; N-Formylmethionine; Phenylalanine; Polyamines; Putrescine; RNA, Transfer; Spectrometry, Fluorescence; Spectrophotometry; Spermidine; Spermine; Yeasts | 1975 |
Interrelations between polyamines and nucleic acids: changes of polyamine and nucleic acid concentrations in the developing rat brain.
Topics: Aging; Animals; Brain; DNA; Nerve Tissue Proteins; Polyamines; Putrescine; Rats; RNA; Spermidine; Spermine | 1975 |
Putrescine, spermidine, N-acetylspermidine and spermine in the urine of patients with leukaemias and tumors.
Topics: Age Factors; Chromatography, Ion Exchange; Female; Humans; Leukemia; Male; Neoplasms; Putrescine; Sex Factors; Spectrophotometry, Infrared; Spermidine; Spermine | 1975 |
Regional distribution of putrescine, spermidine and spermine in relation to the distribution of RNA and DNA in the rat nervous system.
Topics: Animals; Brain Chemistry; Cerebellum; Chromatography, Thin Layer; Diencephalon; DNA; Female; Medulla Oblongata; Mesencephalon; Nerve Tissue Proteins; Organ Specificity; Peripheral Nerves; Putrescine; Rats; RNA; Spermidine; Spermine; Spinal Cord; Telencephalon | 1975 |
Antisera to gonadotrophins and placental function in mice. I. Effect on polyamine content.
Topics: Animals; Cross Reactions; DNA; Female; Immune Sera; Luteinizing Hormone; Mice; Placenta; Polyamines; Pregnancy; Prolactin; Putrescine; RNA; Sheep; Spermidine; Spermine | 1975 |
Effects of polyamines on amino acid incorporation into protein by cerebral and cerebellar as well as "neuronal" and "glial" nuclei of rat brain.
Topics: Amino Acids; Animals; Brain; Cell Nucleus; Cerebellum; Magnesium; Nerve Tissue Proteins; Neuroglia; Neurons; Protein Biosynthesis; Rats; Ribosomes; Spermidine; Spermine | 1975 |
Changes of liver and kidney polyamine levels during aging.
Topics: Aging; Animals; Kidney; Liver; Male; Rats; Spermidine; Spermine | 1975 |
Biosynthesis of histamine and putrescine in mice during post-natal development and its hormone dependence.
Topics: Age Factors; Animals; Castration; Female; Histamine; Histidine Decarboxylase; Kidney; Liver; Male; Mice; Ornithine Decarboxylase; Putrescine; Sex Factors; Spermidine; Spermine; Weaning | 1975 |
Urinary polyamine levels in the diagnosis of carcinoma of the prostate.
Topics: Aged; Carcinoma; Diagnosis, Differential; Electrophoresis, Paper; Humans; Male; Middle Aged; Polyamines; Prostatic Neoplasms; Putrescine; Spermidine; Spermine | 1975 |
Polyamine alterations in blood of male homozygotes and heterozygotes for cystic fibrosis.
Topics: Cystic Fibrosis; Female; Heterozygote; Homozygote; Humans; Male; Sex Factors; Spermidine; Spermine | 1975 |
Effect of DL-alpha-hydrazino-delta-aminovaleric acid, an inhibitor of ornithine decarboxylase, on polyamine metabolism in isoproterenol-stimulated mouse parotid glands.
Topics: Adenosylmethionine Decarboxylase; Animals; Binding, Competitive; Carboxy-Lyases; DNA; Hydrazines; In Vitro Techniques; Isoproterenol; Male; Mice; Mitoguazone; Mitosis; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Parotid Gland; Polyamines; Putrescine; RNA; Spermidine; Spermine; Stimulation, Chemical; Valine | 1975 |
Estimation of urinary diamines and polyamines by thin-layer chromatography.
Topics: Breast Neoplasms; Cadaverine; Chromatography, Thin Layer; Dansyl Compounds; Diamines; Humans; Melanoma; Multiple Myeloma; Polyamines; Putrescine; Spermidine; Spermine | 1975 |
High-speed liquid chromatographic determination of putrescine, spermidine and spermine.
Topics: Chromatography; Putrescine; Solvents; Spermidine; Spermine; Tosyl Compounds | 1975 |
Polyamines are necessary for maximum in vitro synthesis of globin peptides and play a role in chain initiation.
Topics: Animals; Cell-Free System; Dialysis; Edeine; Globins; Kinetics; Leucine; Magnesium; Peptide Chain Initiation, Translational; Peptide Fragments; Polyamines; Potassium Chloride; Rabbits; Reticulocytes; Ribosomes; Spermidine; Spermine; Stimulation, Chemical; Ultrafiltration | 1975 |
Charge effects in the activation of adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cattle; Cell Membrane; Enzyme Activation; Fluorides; Guanosine Triphosphate; Kinetics; Lysine; Magnesium; Muramidase; Peptides; Potassium Chloride; Prostaglandins E; Ribonucleases; Spermidine; Spermine; Thyroid Gland; Thyrotropin | 1975 |
The uptake of spermidine and spermine by slices of mouse cerebral hemispheres.
Topics: Animals; Brain; Cadaverine; Cerebral Cortex; Cyanides; Dinitrophenols; Female; In Vitro Techniques; Mice; Putrescine; Spermidine; Spermine | 1975 |
DNA-dependent RNA polymerases I and II from kidney. Effect of polyamines on the in vitro transcription of DNA and chromatin.
Topics: Animals; Cell Nucleus; Chromatin; Chromatography, Ion Exchange; DNA; DNA-Directed RNA Polymerases; Kidney; Kinetics; Putrescine; Spermidine; Spermine; Swine; Templates, Genetic; Transcription, Genetic; Uracil Nucleotides | 1975 |
Polyamine excretion in the urine of cancer patients.
Topics: Adult; Aged; Cadaverine; Female; Humans; Male; Middle Aged; Neoplasms; Polyamines; Putrescine; Spermidine; Spermine | 1975 |
Polyamines: a high correlation with cell replication.
Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Cells, Cultured; DNA, Neoplasm; Nitrosourea Compounds; Polyamines; Putrescine; Rats; Spermidine; Spermine; Time Factors | 1975 |
Changes in polyamine metabolism in WI38 cells stimulated to proliferate.
Topics: Animals; Blood Proteins; Cattle; Cell Division; Cell Line; Culture Media; DNA; Fibroblasts; Humans; Lung; Polyamines; Putrescine; Spermidine; Spermine; Thymidine; Tritium | 1975 |
[Physiological function of polyamines].
Topics: Animals; Carbohydrate Metabolism; Cell Division; Nucleic Acids; Polyamines; Protein Biosynthesis; Putrescine; Spermidine; Spermine | 1975 |
A new fluorometric method for the determination of spermidine and spermine in tissues by thin layer chromatography.
Topics: Animals; Chromatography, Thin Layer; Fluorescamine; Fluorometry; Isoelectric Point; Kidney; Liver; Lung; Male; Myocardium; Pancreas; Prostate; Rats; Spermidine; Spermine; Spiro Compounds; Spleen; Testis; Thymus Gland | 1975 |
Direct determination of polyamines in human serum by radioimmunoassay.
Topics: Animals; Cadaverine; Cross Reactions; Horses; Humans; Neoplasms; Polyamines; Putrescine; Rabbits; Radioimmunoassay; Spermidine; Spermine | 1975 |
The content of unbound polyamines in blood plasma and leukocytes of patients with polycythemia vera.
Topics: Humans; Leukocytes; Polyamines; Polycythemia Vera; Putrescine; Spermidine; Spermine | 1975 |
Elevated spermidine and spermine levels in the blood of psoriasis patients.
Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; Psoriasis; Skin; Spermidine; Spermine | 1975 |
The actions of spermidine and spermine on the central nervous system.
Topics: Animals; Behavior, Animal; Body Temperature; Brain; Brain Chemistry; Drinking Behavior; Feeding Behavior; Injections, Intraventricular; Mice; Paralysis; Putrescine; Rabbits; Respiration; Spermidine; Spermine; Time Factors | 1975 |
Effect of polyamines on phosphorylation of non-histone chromatin proteins from hog liver.
Topics: Animals; Chromatin; Dose-Response Relationship, Drug; Histones; Kinetics; Liver; Magnesium; Nucleoproteins; Polyamines; Protein Kinases; Spermidine; Spermine; Swine | 1975 |
More sensitive automated detection of polyamines in physiological fluids and tissue extracts with omicron-phthalaldehyde.
Topics: Aldehydes; Amniotic Fluid; Animals; Autoanalysis; Brain Neoplasms; Evaluation Studies as Topic; Female; Humans; Indicators and Reagents; Microchemistry; Neoplasms, Experimental; Phthalic Acids; Polyamines; Pregnancy; Putrescine; Rats; Spectrometry, Fluorescence; Spermidine; Spermine | 1975 |
Polyamines and nucleic acids in brains and hearts of newborn and adult autophagous and heterophagous vertebrates.
Topics: Animals; Animals, Newborn; Brain Chemistry; Chickens; Columbidae; Cricetinae; DNA; Ducks; Female; Guinea Pigs; Male; Muscle Proteins; Myocardium; Nerve Tissue Proteins; Organ Specificity; Parrots; Polyamines; Putrescine; Rats; RNA; Species Specificity; Spermidine; Spermine | 1975 |
Urinary polyamines in patients with gastric cancer and their change after gastrectomy.
Topics: Gastrectomy; Humans; Polyamines; Spermidine; Spermine; Stomach Neoplasms | 1975 |
Alterations in the accumulation patterns of polyamines in brains of myelin-deficient mice.
Topics: Adenosylmethionine Decarboxylase; Animals; Brain; Brain Chemistry; Mice; Movement Disorders; Ornithine Decarboxylase; Polyamines; Putrescine; Rodent Diseases; Spermidine; Spermine | 1975 |
Polyamines in vaccinia virions and polypeptides released from viral cores by acid extraction.
Topics: Arginine; HeLa Cells; Ornithine; Peptides; Polyamines; Spermidine; Spermine; Sulfuric Acids; Vaccinia; Vaccinia virus; Viral Proteins | 1975 |
Ligand-exchange chromatography of diamines and polyamines.
Topics: Chromatography, Ion Exchange; Diamines; Polyamines; Spermidine; Spermine | 1975 |
Characterization of a naturally occurring diamine auxotroph of Veillonella alcalescens.
Topics: Bacterial Proteins; Cadaverine; Diamines; Magnesium; Mutation; Polyamines; Putrescine; RNA, Bacterial; Spermidine; Spermine; Veillonella | 1975 |
In vitro protein synthesis at elevated temperature by an extract of an extreme thermophile. Effects of polyamines on the polyuridylic acid-directed reaction.
Topics: Bacteria; Ethylenediamines; Kinetics; Magnesium; Phenylalanine; Poly U; Polyamines; Protein Biosynthesis; Putrescine; Ribosomes; RNA, Transfer; Spermidine; Spermine; Structure-Activity Relationship; Temperature | 1975 |
Modification of the metabolism of rat epididymal spermatozoa by spermine.
Topics: Animals; Calcium; Epididymis; Fructose; In Vitro Techniques; Male; Prostate; Putrescine; Pyruvates; Rats; Spermatozoa; Spermidine; Spermine | 1975 |
Change of substrate specificity by polyamines of ribonucleases which hydrolyze ribonucleic acid at linkages attached to pyrimidine nucleotides.
Topics: Animals; Aspergillus; Cattle; Horses; Kinetics; Pancreas; Polyamines; Putrescine; Pyrimidines; Ribonucleases; Species Specificity; Spermidine; Spermine; Structure-Activity Relationship; Submandibular Gland | 1975 |
Effects of external osmolality on polyamine metabolism in HeLa cells.
Topics: Culture Media; DNA; HeLa Cells; Ornithine Decarboxylase; Osmolar Concentration; Polyamines; Protein Biosynthesis; Putrescine; Sodium Chloride; Spermidine; Spermine; Transcription, Genetic | 1975 |
Polyamine metabolism in a rat brain tumor cell line: its relationship to the growth rate.
Topics: Adenosylmethionine Decarboxylase; Cell Division; Cell Line; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine | 1975 |
Polyamines in cystic fibrosis.
Topics: Bile; Cystic Fibrosis; Duodenum; Humans; Intestinal Secretions; Polyamines; Saliva; Spermidine; Spermine; Sweat | 1975 |
Effect of nucleic-acid-binding compounds on the hydrolytic activity of various ribonucleases.
Topics: Acridines; Aminoquinolines; Animals; Binding Sites; Cattle; Chloroquine; Ethidium; Kinetics; Pancreas; Primaquine; Proflavine; Protein Binding; Quinacrine; Ribonucleases; Spermidine; Spermine; Structure-Activity Relationship | 1975 |
Metabolism of polyamines in mouse neuroblastoma cells in culture: formation of GABA and putreanine.
Topics: Aminobutyrates; Cell Line; gamma-Aminobutyric Acid; Neuroblastoma; Ornithine; Polyamines; Putrescine; Spermidine; Spermine | 1975 |
Effects of polyamines and methylglyoxal bis(guanylhydrazone) on hepatic nuclear structure and deoxyribonucleic acid template activity.
Topics: Animals; Cattle; Cell Nucleus; DNA; DNA Nucleotidyltransferases; Guanidines; Histones; In Vitro Techniques; Liver; Male; Microscopy, Electron; Mitoguazone; Nucleic Acid Denaturation; Polyamines; Putrescine; Rats; Spermidine; Spermine; Templates, Genetic; Thymus Gland | 1975 |
A rapid and simple determination of histamine and polyamines.
Topics: Animals; Brain Chemistry; Chromatography, Ion Exchange; Female; Histamine; Kidney; Liver; Polyamines; Rats; Spermidine; Spermine | 1975 |
The effects of polyamines on cardiac protein biosynthesis.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Cell Membrane; Cell-Free System; In Vitro Techniques; Magnesium; Muscle Proteins; Myocardium; Perfusion; Phenylalanine; Polyamines; Protein Biosynthesis; Putrescine; Rats; Spermidine; Spermine | 1975 |
Effects of polyamines on the central nervous system.
Topics: Animals; Avoidance Learning; Body Temperature; Brain; Lethal Dose 50; Male; Methamphetamine; Mice; Motor Activity; Pentobarbital; Sleep; Spermidine; Spermine; Strychnine | 1975 |
Translation of alfalfa mosaic virus RNA. Effect of polyamines.
Topics: Magnesium; Medicago sativa; Mosaic Viruses; Plant Viruses; Potassium Chloride; Protein Biosynthesis; RNA, Viral; Seeds; Species Specificity; Spermidine; Spermine; Tobacco Mosaic Virus; Triticum | 1976 |
Polyamines can replace the dialyzable component from crude reticulocyte initiation factors.
Topics: Animals; Peptide Chain Initiation, Translational; Peptide Initiation Factors; Rabbits; Reticulocytes; RNA, Messenger; Spermidine; Spermine | 1976 |
Diacridines: bifunctional intercalators. II. The biological effects of putrescine, sperimidine and spermine diacridines on HeLa cells and on the L-1210 and P-388 leukemia cells.
Topics: Acridines; Animals; Cell Division; HeLa Cells; Leukemia L1210; Leukemia, Experimental; Mice; Protein Biosynthesis; Putrescine; Spermidine; Spermine; Structure-Activity Relationship | 1976 |
Insulin-like effect of some polyamines on lipoprotein lipase from rat adipose tissue.
Topics: Adipose Tissue; Animals; Insulin; Kinetics; Lipoprotein Lipase; Male; Putrescine; Rats; Spermidine; Spermine | 1976 |
The relationship of polyamines in cerebrospinal fluid to the presence of central nervous system tumors.
Topics: Adenoma; Astrocytoma; Brain Neoplasms; Central Nervous System Diseases; Glioma; Humans; Medulloblastoma; Meningioma; Pituitary Neoplasms; Polyamines; Putrescine; Spermidine; Spermine | 1976 |
Occurrence and formation of gamma-glutamylputrescine in mammalian brain.
Topics: Animals; Brain; Crystallization; Glutamates; Putrescine; Rats; Spermidine; Spermine | 1976 |
Cyclic change in polyamine concentrations in sea urchin eggs related with cleavage cycle.
Topics: Animals; Cell Division; Embryo, Nonmammalian; Female; Fertilization; Ovum; Putrescine; Sea Urchins; Spermidine; Spermine; Time Factors | 1976 |
Occurrence and characterization of new polyamines in the extreme thermophile Caldariella acidophila.
Topics: Bacteria; Cell Division; Electrophoresis, Paper; Gas Chromatography-Mass Spectrometry; Hot Temperature; Polyamines; Putrescine; Spermidine; Spermine; Time Factors | 1976 |
Subcellular distribution of S-adenosylmethionine decarboxylase in rat liver. Evidence of decarboxylation of S-adenosylmethionine separate from synthesis of spermidine.
Topics: Adenosylmethionine Decarboxylase; Animals; Brain; Carboxy-Lyases; Chickens; Decarboxylation; Ferrets; Gerbillinae; Guinea Pigs; Humans; Kidney; Liver; Male; Mice; Putrescine; Rabbits; Rats; S-Adenosylmethionine; Species Specificity; Spermidine; Spermine; Spleen; Subcellular Fractions | 1976 |
Polyamine concentrations in bone marrow aspirates of children with leukemia and other malignancies.
Topics: Bone Marrow; Child; Humans; Leukemia; Leukemia, Lymphoid; Polyamines; Putrescine; Remission, Spontaneous; Spermidine; Spermine | 1976 |
Urinary putrescine, spermidine, and spermine in human blood and solid cancers and in an experimental gastric tumor of rats.
Topics: Animals; Female; Humans; Leukemia; Lymphoma; Methylnitronitrosoguanidine; Neoplasms; Neoplasms, Experimental; Polyamines; Pregnancy; Putrescine; Rats; Spermidine; Spermine; Stomach Neoplasms | 1976 |
Polyamine transport and metabolism in mouse mammary gland. General properties and hormonal regulation.
Topics: Animals; Biological Transport, Active; Cells, Cultured; Female; Insulin; Kinetics; Mammary Glands, Animal; Mice; Polyamines; Pregnancy; Prolactin; Putrescine; Spermidine; Spermine; Temperature | 1976 |
Fluctuations of unbound whole blood polyamine levels during the menstrual cycle.
Topics: Adult; Castration; Contraceptives, Oral, Combined; Female; Humans; Male; Menstruation; Spermidine; Spermine | 1976 |
Changes in the composition of the excurrent duct system of the rat testis during postnatal development.
Topics: Animals; DNA; Epididymis; Glycogen; Lipids; Liver; Male; Phospholipids; Phosphorus; Prostate; Proteins; Rats; RNA; Sexual Maturation; Sialic Acids; Spermidine; Spermine; Testis; Urinary Bladder; Vas Deferens | 1976 |
Effect of polyamines, ions and epinephrine on triolein hydrolyzing activity of rat ventricular extracts.
Topics: Animals; Calcium; Heart Ventricles; Heparin; Kinetics; Lipase; Lipid Mobilization; Magnesium; Male; Myocardium; Polyamines; Potassium; Protamines; Rats; Sodium; Spermidine; Spermine; Triolein | 1976 |
Synthesis of hepatic polyamines, ribonucleic acid and S-adenosylmethionine in normal and oestrogen-treated chicks.
Topics: Adenosylmethionine Decarboxylase; Age Factors; Animals; Cell Nucleolus; Cell Nucleus; Chickens; Cycloheximide; DNA-Directed RNA Polymerases; Estradiol; Liver; Male; Methionine Adenosyltransferase; Nucleic Acids; Ornithine Decarboxylase; Polyamines; RNA; S-Adenosylmethionine; Spermidine; Spermidine Synthase; Spermine; Spermine Synthase; Starvation | 1976 |
[The diagnostic value of erythrocyte polyamines (EPA) in prostatic adenocarcinoma (PA): apropos of 100 patients].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Erythrocytes; Humans; Male; Middle Aged; Neoplasm Staging; Predictive Value of Tests; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Sensitivity and Specificity; Spermidine; Spermine | 1992 |
Spermine down-regulates superoxide generation induced by fMet-Leu-Phe in electropermeabilized human neutrophils.
Topics: Cell Membrane Permeability; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Putrescine; Spermidine; Spermine; Superoxides | 1992 |
Adherence to respiratory epithelia by recombinant Escherichia coli expressing Klebsiella pneumoniae type 3 fimbrial gene products.
Topics: Acetates; Acetic Acid; Adhesins, Bacterial; Bacterial Adhesion; Bacterial Proteins; Cheek; Chromosome Mapping; Cloning, Molecular; Epithelium; Escherichia coli; Fimbriae Proteins; Glucose; Humans; Immunoglobulin Fab Fragments; In Vitro Techniques; Klebsiella pneumoniae; Lactose; Lung; Lysine; Microbial Collagenase; Periodic Acid; Polylysine; Protamines; Recombinant Proteins; Spermidine; Spermine; Trachea | 1992 |
Effects of cyclosporin A and a non-immunosuppressive analogue, O-acetyl cyclosporin A, upon the growth of parent and multidrug resistant human lung cancer cells in vitro.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Cell Line; Cell Survival; Cyclosporine; Cyclosporins; Dose-Response Relationship, Drug; Drug Resistance; Eflornithine; Humans; In Vitro Techniques; Lung Neoplasms; Putrescine; Spermidine; Spermine | 1992 |
The interaction of spermine with the ryanodine receptor from skeletal muscle.
Topics: Animals; Calcium; Calcium Channels; In Vitro Techniques; Kinetics; Muscle Proteins; Muscles; Putrescine; Rabbits; Receptors, Cholinergic; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sodium Chloride; Spermidine; Spermine | 1992 |
Implication of the polyamines in the neurotoxic effects of N-methyl-D-aspartate.
Topics: Animals; Cell Membrane; Choline O-Acetyltransferase; Corpus Striatum; Dizocilpine Maleate; Glutamate Decarboxylase; Infusions, Parenteral; Isoquinolines; Microinjections; N-Methylaspartate; Neurotoxins; Rats; Receptors, GABA-A; Spermidine; Spermine; Tetrodotoxin | 1992 |
Differing effects of alpha-difluoromethylornithine and CGP 40116 on polyamine levels and infarct volume in a rat model of focal cerebral ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Ischemia; Cerebral Infarction; Eflornithine; Magnetic Resonance Imaging; Male; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Rats, Inbred F344; Spermidine; Spermine | 1992 |
Spermine facilitates the generation of long-term potentiation of evoked potential in the dentate gyrus of anesthetized rats.
Topics: Adrenergic alpha-Antagonists; Anesthesia, General; Animals; Cerebral Ventricles; Electric Stimulation; Evoked Potentials; Hippocampus; Injections, Intraventricular; Male; Piperidines; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Time Factors | 1992 |
Accumulation of wound-inducible ACC synthase transcript in tomato fruit is inhibited by salicylic acid and polyamines.
Topics: Base Sequence; DNA; Gene Expression Regulation, Enzymologic; Kinetics; Lyases; Molecular Sequence Data; Oligonucleotide Probes; Plants; Polyamines; Polymerase Chain Reaction; Putrescine; RNA; RNA, Ribosomal; Salicylates; Salicylic Acid; Spermidine; Spermine; Transcription, Genetic; Wounds and Injuries | 1992 |
Evidence for polyamine channels in protoplasts and vacuoles of Arabidopsis thaliana cells.
Topics: Cell Membrane; Chlorides; Ion Channels; Kinetics; Membrane Potentials; Plant Physiological Phenomena; Polyamines; Protoplasts; Putrescine; Spermidine; Spermine; Vacuoles | 1992 |
Developmental expression of ornithine and S-adenosylmethionine decarboxylases in mouse brain.
Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Brain; DNA Probes; Gene Expression Regulation, Enzymologic; Kinetics; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Putrescine; RNA; RNA, Messenger; Spermidine; Spermine | 1992 |
Interactions between natural polyamines and tRNA: an 15N NMR analysis.
Topics: Escherichia coli; Magnetic Resonance Spectroscopy; Molecular Conformation; Nitrogen Isotopes; Polyamines; Putrescine; RNA, Transfer; Spermidine; Spermine | 1992 |
Polyamine and histopathological changes after unilateral endotoxin-induced uveitis and its contralateral effects.
Topics: Animals; Anterior Eye Segment; Endotoxins; Escherichia coli; Eye Proteins; Leukocyte Count; Lipopolysaccharides; Putrescine; Rabbits; Retina; Spermidine; Spermine; Uveitis | 1992 |
The phosphonic acid analog of phosphatidylglycerol phosphate: influence on Escherichia coli growth and physiology.
Topics: Butylene Glycols; Cells, Cultured; Escherichia coli; Glycerophosphates; Magnesium Chloride; Organophosphonates; Organophosphorus Compounds; Phosphatidylglycerols; Spermidine; Spermine | 1992 |
Polyamines as modulators of lipoperoxidation.
Topics: Animals; Iron; Lipid Peroxidation; Liposomes; Liver; Luminescent Measurements; Male; Malondialdehyde; Phospholipids; Polyamines; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine | 1992 |
Androgenic control of polyamine concentrations in rat epididymis.
Topics: Androgens; Animals; Epididymis; Flutamide; Male; Orchiectomy; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Testosterone | 1992 |
Role of polyamines in the growth of hormone-responsive and -resistant human breast cancer cells in nude mice.
Topics: Animals; Breast Neoplasms; Cell Division; Drug Resistance; Drug Screening Assays, Antitumor; Eflornithine; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Polyamines; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1992 |
Increased survival of L1210 leukemic mice by prevention of the utilization of extracellular polyamines. Studies using a polyamine-uptake mutant, antibiotics and a polyamine-deficient diet.
Topics: Animals; Anti-Bacterial Agents; Biological Transport; Carbon Radioisotopes; Drug Resistance; Eflornithine; Extracellular Space; Female; Leukemia L1210; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mitoguazone; Mutation; Polyamines; Sex Factors; Spermidine; Spermine; Tritium | 1992 |
A proposed function for spermine and spermidine: protection of replicating DNA against damage by singlet oxygen.
Topics: DNA; DNA Damage; DNA Replication; Models, Theoretical; Oxidation-Reduction; Reactive Oxygen Species; Spermidine; Spermine | 1992 |
Spermine and spermidine protection of plasmid DNA against single-strand breaks induced by singlet oxygen.
Topics: DNA; DNA Damage; In Vitro Techniques; Plasmids; Reactive Oxygen Species; Spermidine; Spermine | 1992 |
Regulation of S-adenosylmethionine decarboxylase activity by alterations in the intracellular polyamine content.
Topics: Adenosylmethionine Decarboxylase; Animals; Cells, Cultured; Chlorocebus aethiops; CHO Cells; Cricetinae; Diamines; Eflornithine; Gene Expression Regulation; In Vitro Techniques; Ornithine Decarboxylase Inhibitors; Polyamines; Spermidine; Spermine; Spermine Synthase; Transcription, Genetic; Transfection | 1992 |
Neurotoxic effects of the intrastriatal injection of spermine and spermidine: lack of involvement of NMDA receptors.
Topics: Animals; Choline O-Acetyltransferase; Corpus Striatum; Dizocilpine Maleate; Glutamate Decarboxylase; Injections; Male; Nervous System; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1992 |
A novel nuclear 42-kDa casein kinase identified in Chironomus tentans.
Topics: Animals; Casein Kinases; Caseins; Chironomidae; Dichlororibofuranosylbenzimidazole; Heparin; Molecular Weight; Phosphorylation; Phosvitin; Protein Kinases; Spermidine; Spermine | 1992 |
Development changes of polyamine biosynthesis in rat liver.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Aging; Animals; Animals, Newborn; Gestational Age; Liver; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine | 1992 |
Effect of L-arginine on pancreatic arginase activity and polyamines in alloxan treated rats.
Topics: Animals; Arginase; Arginine; Diabetes Mellitus, Experimental; Male; Pancreas; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1992 |
Polyamine metabolism in enterocytes isolated from newborn pigs.
Topics: Animals; Animals, Newborn; Arginine; Cell Differentiation; Cell Division; Glutamine; Intestinal Mucosa; Polyamines; Putrescine; Spermidine; Spermine; Swine; Temperature | 1992 |
Erythrocyte spermidine levels in IDDM patients.
Topics: Adult; Albuminuria; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Erythrocytes; Female; Humans; Male; Middle Aged; Reference Values; Spermidine; Spermine | 1992 |
Changes in brain polyamine levels following head injury.
Topics: Animals; Body Water; Brain; Cerebral Cortex; Eflornithine; Head Injuries, Closed; Male; Motor Activity; Posture; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Time Factors | 1992 |
Estradiol-17 beta modifies the induction of spermidine/spermine N1-acetyltransferase activity in the liver of lipopolysaccharide-treated mice.
Topics: Acetyltransferases; Animals; Enzyme Induction; Estradiol; Gene Expression Regulation, Enzymologic; Lipopolysaccharides; Liver; Lung; Male; Mice; Mice, Inbred BALB C; Ornithine Decarboxylase; Spermidine; Spermine; Spleen | 1992 |
A tentacle gel simplifies the purification of ceruloplasmin.
Topics: Animals; Ceruloplasmin; Chromatography, Agarose; Cyanogen Bromide; Electrophoresis, Disc; Polyethyleneimine; Spermidine; Spermine; Swine; Trinitrobenzenesulfonic Acid | 1992 |
Role of ornithine decarboxylase suppression and polyamine depletion in the antiproliferative activity of polyamine analogs.
Topics: Adenosylmethionine Decarboxylase; Animals; Biogenic Polyamines; Cell Division; CHO Cells; Cricetinae; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Spermidine; Spermine; Transfection; Trypanosoma | 1992 |
High-performance liquid chromatographic determination of free polyamines in human seminal plasma.
Topics: Adolescent; Adult; Biogenic Polyamines; Body Fluids; Chromatography, High Pressure Liquid; Humans; Male; Middle Aged; Putrescine; Semen; Spermidine; Spermine; Temperature; Ultrafiltration | 1992 |
The binding of polyamines and magnesium to DNA.
Topics: Animals; Arsenazo III; Cations; Cattle; DNA; Magnesium; Polyamines; Spectrophotometry; Spermidine; Spermine | 1992 |
Effects of spermidine synthase inhibition in cultured chick embryo fibroblasts.
Topics: Animals; Cell Division; Cells, Cultured; Chick Embryo; Cyclohexylamines; DNA; Fibroblasts; Leucine; Protein Biosynthesis; Putrescine; Spermidine; Spermidine Synthase; Spermine | 1992 |
Changes in polyamines during embryonic development of Atlantic salmon, Salmo salar.
Topics: Animals; Cadaverine; Embryonic and Fetal Development; Female; Ornithine Decarboxylase; Ovum; Polyamines; Putrescine; Salmon; Spermidine; Spermine | 1992 |
Evidence that spermine, spermidine, and putrescine are transported electrophoretically in mitochondria by a specific polyamine uniporter.
Topics: Animals; Biological Transport; Hydrogen-Ion Concentration; Kinetics; Lysine; Membrane Potentials; Mitochondria, Liver; Ornithine; Putrescine; Rats; Spermidine; Spermine; Temperature; Tetraethylammonium; Tetraethylammonium Compounds; Thermodynamics | 1992 |
Selective release of spermine and spermidine from the rat striatum by N-methyl-D-aspartate receptor activation in vivo.
Topics: Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dizocilpine Maleate; Kainic Acid; Male; Polyamines; Potassium; Putrescine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1992 |
Changes in regional polyamine profiles in rat brains after transient cerebral ischemia (single versus repetitive ischemia): evidence for release of polyamines from injured neurons.
Topics: Animals; Brain; Female; Gerbillinae; Ischemic Attack, Transient; Neurons; Organ Specificity; Polyamines; Putrescine; Spermidine; Spermine; Time Factors | 1992 |
Differential effects of polyamine homologues on the prevention of DL-alpha-difluoromethylornithine-mediated inhibition of malignant cell growth and normal immune response.
Topics: Animals; Cell Division; Cell Line; Concanavalin A; Cytotoxicity, Immunologic; Eflornithine; Isomerism; Lymphocyte Activation; Lymphoma; Male; Mast-Cell Sarcoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Polyamines; Putrescine; Spermidine; Spermine | 1992 |
Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumour cells.
Topics: Brain Neoplasms; Cell Nucleus; Chromatin; Culture Media, Serum-Free; Deoxyribonuclease I; Eflornithine; Humans; Intracellular Fluid; Kinetics; Micrococcal Nuclease; Polyamines; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1992 |
Polyamines and estrogen-receptor concentrations in human colorectal carcinomas.
Topics: Adenocarcinoma; Adult; Aged; Carcinoembryonic Antigen; Colorectal Neoplasms; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Neoplasm Staging; Putrescine; Receptors, Estrogen; Spermidine; Spermine | 1992 |
Polyamines enhance recovery after sciatic nerve trauma in the rat.
Topics: Animals; Axons; Female; Motor Activity; Movement; Nerve Regeneration; Rats; Rats, Inbred Strains; Sciatic Nerve; Sensation; Spermidine; Spermine | 1992 |
Regulation of plant cell-wall pectin methyl esterase by polyamines--interactions with the effects of metal ions.
Topics: Cadaverine; Calcium Chloride; Carboxylic Ester Hydrolases; Enzyme Activation; Glycine max; Kinetics; Models, Biological; Pectins; Plants; Polyamines; Putrescine; Sodium Chloride; Spermidine; Spermine | 1992 |
Sex steroid hormone receptors, epidermal growth factor receptor, and polyamines in human colorectal cancer.
Topics: Adult; Aged; Colon; Colorectal Neoplasms; ErbB Receptors; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Polyamines; Putrescine; Receptors, Estrogen; Receptors, Progesterone; Spermidine; Spermine | 1992 |
Characteristics of putrescine uptake and subsequent GABA formation in primary cultured astrocytes from normal C57BL/6J and epileptic DBA/2J mouse brain cortices.
Topics: Animals; Astrocytes; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Cerebral Cortex; Epilepsy; gamma-Aminobutyric Acid; Kinetics; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Putrescine; Radioisotope Dilution Technique; Spermidine; Spermine | 1992 |
Polyamine metabolism in colonic mucosa from patients with ulcerative colitis.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Adolescent; Adult; Blotting, Northern; Colitis, Ulcerative; Colonoscopy; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Ornithine Decarboxylase; Polyamines; Remission Induction; RNA, Messenger; Spermidine; Spermine | 1992 |
Inhibition of mast cell secretion by oxidation products of natural polyamines.
Topics: Animals; Cattle; Dose-Response Relationship, Drug; Humans; Male; Mast Cells; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; p-Methoxy-N-methylphenethylamine; Polyamine Oxidase; Rats; Rats, Inbred Strains; Serotonin; Spermidine; Spermine | 1992 |
Cooperative binding of polyamines induces the Escherichia coli single-strand binding protein-DNA binding mode transitions.
Topics: Cations; DNA-Binding Proteins; DNA, Single-Stranded; Escherichia coli; Macromolecular Substances; Magnesium; Poly T; Polyamines; Protein Conformation; Sodium Chloride; Spermidine; Spermine | 1992 |
Polyamine concentration in rat milk and food, human milk, and infant formulas.
Topics: Animal Feed; Animals; Female; Humans; Infant; Infant Food; Intestinal Mucosa; Milk; Milk, Human; Permeability; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1992 |
Polyamines in human and rat milk and in infant formulas.
Topics: Animals; Cadaverine; Female; Humans; Infant; Infant Food; Milk; Milk, Human; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1992 |
Characterization of the spermidine-dependent, sequence-specific endoribonuclease that requires transfer RNA for its activity.
Topics: Animals; Base Sequence; Cell Line; Chromatography, Gel; Endoribonucleases; Hydrogen-Ion Concentration; Magnesium; Mice; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; RNA, Transfer; Spermidine; Spermine; Temperature | 1992 |
Characterization of a human recombinant receptor-linked protein tyrosine phosphatase.
Topics: Baculoviridae; Brain; Cations, Divalent; Chromatography, Gel; DNA; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Viral; Genes, Viral; Glycosylation; Heparin; Humans; Metals; Phosphoprotein Phosphatases; Protein Tyrosine Phosphatases; Recombinant Proteins; Spermidine; Spermine; Substrate Specificity | 1991 |
The amino aldehydes produced by spermine and spermidine oxidation with maize polyamine oxidase have anti-leishmanial effect.
Topics: Aldehydes; Animals; Antiprotozoal Agents; Catalysis; Durapatite; Hydroxyapatites; Leishmaniasis; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Spermine; Zea mays | 1991 |
Polyamines modulate events mediated by the N-methyl-D-aspartate (NMDA) receptor complex through an ifenprodil-insensitive pathway: in vivo measurements of cyclic GMP in the cerebellum.
Topics: Animals; Biogenic Polyamines; Cerebellum; Cyclic GMP; Dizocilpine Maleate; Injections, Intraventricular; Male; Methamphetamine; Mice; Neural Pathways; Ornithine; Pentylenetetrazole; Piperidines; Putrescine; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1991 |
Polyamine biosynthesis in cells infected with different clinical isolates of human cytomegalovirus.
Topics: Cell Line; Cytomegalovirus; Humans; Kinetics; Polyamines; Putrescine; Spermidine; Spermine; Viral Plaque Assay; Virion | 1991 |
Interaction of pyrophosphate ion with di-, tri- and tetra-amines in aqueous solution: a potentiometric and calorimetric study.
Topics: Amines; Calorimetry; Diphosphates; Hydrogen-Ion Concentration; Potentiometry; Solutions; Spermidine; Spermine; Thermodynamics; Water | 1991 |
Glutamate and glycine co-activate while polyamines merely modulate the NMDA receptor complex.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Antagonists; Animals; Biguanides; Binding, Competitive; Biogenic Polyamines; Biotransformation; Brain; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1991 |
Polyamine and ifenprodil interactions with the NMDA receptor's glycine site.
Topics: Animals; Binding Sites; Drug Interactions; Glutamates; Glutamic Acid; Glycine; Male; Piperidines; Polyamines; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Statistics as Topic | 1991 |
Polyamines and polyamino acids regulation of cytosolic tyrosine protein (Tyr-P) kinase from human erythrocytes.
Topics: Angiotensin II; Chondroitin; Cytosol; Dextran Sulfate; Dextrans; Erythrocytes; Heparin; Humans; Insulin; Intercellular Signaling Peptides and Proteins; Peptides; Phosphorylation; Polyamines; Polylysine; Protein-Tyrosine Kinases; Putrescine; Spermidine; Spermine | 1990 |
Induction of angiogenesis in chick yolk-sac membrane by polyamines and its inhibition by tissue inhibitors of metalloproteinases (TIMP and TIMP-2).
Topics: Animals; Chick Embryo; Glycoproteins; Histamine; Kinetics; Metalloendopeptidases; Neovascularization, Pathologic; Polyamines; Polylysine; Putrescine; Spermidine; Spermine; Tissue Inhibitor of Metalloproteinases; Yolk Sac | 1990 |
The effect of age on small bowel adaptation and growth after proximal enterectomy.
Topics: Adaptation, Physiological; Aging; Animals; Body Weight; DNA; Intestinal Mucosa; Intestine, Small; Male; Proteins; Putrescine; Rats; Rats, Inbred F344; RNA; Spermidine; Spermine | 1990 |
Erythrocyte polyamine levels in human prostatic carcinoma.
Topics: Adenocarcinoma; Aged; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms; Spermidine; Spermine | 1990 |
Polyamines and ornithine decarboxylase during repair of duodenal mucosa after stress in rats.
Topics: Animals; DNA; Duodenum; Eflornithine; Intestinal Mucosa; Male; Ornithine Decarboxylase; Polyamines; Proteins; Putrescine; Rats; Rats, Inbred Strains; RNA; Spermidine; Spermine; Stress, Physiological | 1991 |
Differential response of rat brain polyamines to convulsant agents.
Topics: Animals; Biogenic Polyamines; Body Weight; Brain; Convulsants; Hexachlorocyclohexane; Kainic Acid; Male; Ornithine Decarboxylase; Pentylenetetrazole; Picrotoxin; Putrescine; Rats; Rats, Inbred Strains; Sesterterpenes; Spermidine; Spermine | 1991 |
Polyamines and long-term disuse of rat parotid glands.
Topics: Animals; DNA; Food, Formulated; Humans; Organ Size; Ornithine Decarboxylase; Parotid Gland; Polyamines; Putrescine; Rats; Rats, Inbred Strains; RNA; Spermidine; Spermine | 1990 |
Norspermidine inhibits LPS-induced immunoglobulin production in an FCS-independent mechanism different from spermidine and spermine.
Topics: Animals; Culture Media; DNA; Female; Immunoglobulin M; Immunoglobulins; Immunosuppressive Agents; In Vitro Techniques; Mice; Putrescine; RNA; Spermidine; Spermine | 1991 |
Polyamide profiles of porcine milk and of intestinal tissue of pigs during suckling.
Topics: Animals; Animals, Suckling; Chromatography, High Pressure Liquid; DNA; Female; Intestinal Mucosa; Lactation; Milk; Ornithine Decarboxylase; Polyamines; Putrescine; RNA; Spermidine; Spermine; Swine | 1991 |
[Naturally occurring aliphatic polyamines-induced histamine release from rat peritoneal mast cells].
Topics: Animals; Histamine Release; In Vitro Techniques; Male; Mast Cells; Peritoneum; Rats; Rats, Inbred Strains; Spermidine; Spermine; Stimulation, Chemical | 1991 |
Stimulation of proximal small intestinal mucosal growth by luminal polyamines.
Topics: Animals; Cell Line; DNA; DNA Replication; Duodenum; Eflornithine; Intestinal Mucosa; Jejunum; Kinetics; Male; Ornithine Decarboxylase; Proteins; Rats; Rats, Inbred Strains; RNA; Spermidine; Spermine; Thymidine; Tritium | 1991 |
Molecular basis for cellular effects of naturally occurring polyamines.
Topics: Animals; Cadaverine; GTP Phosphohydrolases; GTP-Binding Proteins; Histamine Release; Male; Mast Cells; Peritoneal Cavity; Pertussis Toxin; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Virulence Factors, Bordetella | 1991 |
Naturally occurring aliphatic polyamines-induced histamine release from rat peritoneal mast cells.
Topics: Animals; Cells, Cultured; Histamine Release; Male; Mast Cells; Peritoneal Cavity; Polyamines; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1991 |
Estimation of polyamine binding to macromolecules and ATP in bovine lymphocytes and rat liver.
Topics: Adenosine Triphosphate; Animals; Cattle; DNA; In Vitro Techniques; Liver; Lymphocytes; Magnesium; Osmolar Concentration; Phospholipids; Rats; RNA; Spermidine; Spermine | 1991 |
Deficiencies in DNA replication and cell-cycle progression in polyamine-depleted HeLa cells.
Topics: Cell Cycle; Cell Division; Cell Nucleus; DNA Polymerase II; DNA Replication; Eflornithine; HeLa Cells; Humans; Nuclear Proteins; Polyamines; Putrescine; S Phase; Spermidine; Spermine; Thymidine Monophosphate; Tritium | 1992 |
Reduced growth rate of dimethylhydrazine-induced colon tumors in rats.
Topics: Animals; Body Weight; Cell Division; Colonic Neoplasms; Dimethylhydrazines; Eflornithine; Male; Mitomycin; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1992 |
Polyamine catabolism in rodent and human cells in culture.
Topics: Animals; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Eflornithine; Hot Temperature; Humans; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Rats; Spermidine; Spermine; Tumor Cells, Cultured | 1991 |
Daily cycles of putrescine, spermidine, and spermine in the liver, pineal gland, harderian gland, anterior pituitary, and testes of rats kept in LD 12:12.
Topics: Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Harderian Gland; Liver; Male; Pineal Gland; Pituitary Gland, Anterior; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Testis | 1991 |
Determination of erythrocytic polyamines by reversed-phase liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Cyclohexanes; Dansyl Compounds; Erythrocytes; Humans; Polyamines; Putrescine; Reference Values; Spermidine; Spermine | 1991 |
Changes in ornithine decarboxylase activity and polyamine levels in response to eight different forms of selenium.
Topics: Adenosylmethionine Decarboxylase; Animals; Cysteine; Enzyme Induction; Female; Liver; Methylation; Organoselenium Compounds; Ornithine Decarboxylase; Oxidation-Reduction; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Selenium; Selenium Compounds; Selenocysteine; Spermidine; Spermine; Structure-Activity Relationship | 1991 |
High-mobility group and other nonhistone substrates for nuclear histone N-acetyltransferase.
Topics: Acetylation; Acetyltransferases; Animals; Cattle; Cell Nucleus; Chromosomal Proteins, Non-Histone; High Mobility Group Proteins; Histone Acetyltransferases; Histones; Hydrogen-Ion Concentration; Polyamines; Saccharomyces cerevisiae Proteins; Spermidine; Spermine; Substrate Specificity | 1991 |
Effect of bis(benzyl)polyamine derivatives on polyamine transport and survival of Brugia pahangi.
Topics: Animals; Benzyl Compounds; Biological Transport; Brugia; Filaricides; Polyamines; Putrescine; Spermidine; Spermine | 1991 |
Leishmania infantum: polyamine biosynthesis and levels during the growth of promastigotes.
Topics: Animals; Decarboxylation; Diminazene; Dogs; Eflornithine; Leishmania donovani; Methionine; Ornithine; Polyamines; Putrescine; Spermidine; Spermine; Trypanocidal Agents | 1991 |
Cell-free translation of American hop latent virus RNA.
Topics: Animals; Cell-Free System; Dithiothreitol; Electrophoresis, Agar Gel; Guanosine; Kinetics; Plant Viruses; Precipitin Tests; Protein Biosynthesis; Rabbits; Reticulocytes; RNA, Viral; Spermidine; Spermine; Triticum | 1991 |
Polyamine metabolism in transient focal ischemia of rat brain.
Topics: Animals; Brain; Cerebral Cortex; Corpus Striatum; Functional Laterality; Ischemic Attack, Transient; Ornithine Decarboxylase; Putrescine; Rats; Reperfusion; Spermidine; Spermine | 1991 |
Hepatic polyamine metabolism in children with Reye's syndrome.
Topics: Child; Humans; Kidney; Liver; Ornithine Carbamoyltransferase; Ornithine Decarboxylase; Polyamines; Putrescine; Reye Syndrome; Spermidine; Spermine; Urea | 1991 |
Polyamines modulate the binding of [3H]MK-801 to the solubilized N-methyl-D-aspartate receptor.
Topics: Animals; Brain; Dizocilpine Maleate; Intracellular Membranes; Male; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Tritium | 1991 |
Assessment of the efficiency of endovesical laser treatment of urinary bladder tumors on the basis of polyamine content measured in the eluent.
Topics: Aged; Biogenic Polyamines; Carcinoma, Transitional Cell; Chromatography, High Pressure Liquid; Female; Humans; Laser Therapy; Male; Middle Aged; Putrescine; Spermidine; Spermine; Urinary Bladder Neoplasms | 1991 |
Enhancement of ouabain and calcium ionophore A23187 of outward transport of polyamines from lymphocytes.
Topics: Acetylation; Biological Transport; Calcimycin; Dinitrophenols; Humans; Lymphocytes; Ouabain; Polyamines; Putrescine; Spermidine; Spermine | 1991 |
Polyamines, vascular smooth muscle, and deoxycorticosterone acetate-salt hypertension.
Topics: Acetylcholine; Animals; Aorta; Arteries; Blood Pressure; Body Weight; Desoxycorticosterone; Dose-Response Relationship, Drug; Eflornithine; Heart; Heart Rate; Hypertension; Male; Muscle, Smooth, Vascular; Nephrectomy; Nitroprusside; Norepinephrine; Organ Size; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Serotonin; Spermidine; Spermine; Tail; Time Factors; Vasoconstriction | 1991 |
Effect on N1,N14-bis-(ethyl)-homospermine (BE-4-4-4) on the growth of U-251 MG and SF-188 human brain tumor cells.
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line; Cell Survival; Humans; Kinetics; Polyamines; Putrescine; Spermidine; Spermine | 1991 |
On the role of polyamines in bone resorption induced by parathyroid hormone.
Topics: Animals; Bone Neoplasms; Bone Resorption; Calcium; Eflornithine; Mice; Ornithine Decarboxylase; Parathyroid Hormone; Polyamines; Sarcoma, Experimental; Skull; Spermidine; Spermine; Tumor Cells, Cultured | 1991 |
Role of spermine in mammalian sperm capacitation and acrosome reaction.
Topics: Acrosome; Animals; Heparin; Male; Putrescine; Sheep; Sperm Capacitation; Spermatozoa; Spermidine; Spermine | 1991 |
Polyamines in rabbit aqueous humor after surgical trauma to the eye.
Topics: Animals; Anterior Chamber; Aqueous Humor; Chromatography, High Pressure Liquid; Eye Proteins; Lenses, Intraocular; Leukocyte Count; Ophthalmologic Surgical Procedures; Putrescine; Rabbits; Spermidine; Spermine | 1991 |
2,4-Dichlorophenoxyacetic acid effects on polyamine biosynthesis.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Cell Division; Cell Line; Culture Media; DNA; Ornithine Decarboxylase; Polyamines; Protein Biosynthesis; Proteins; Putrescine; Spermidine; Spermidine Synthase; Spermine; Spermine Synthase | 1991 |
Effects of cyclosporin A on growth and polyamine metabolism of MOLT-4 T-lymphoblastic leukaemia cells.
Topics: Cell Division; Cyclosporins; Dose-Response Relationship, Drug; Humans; Leukemia-Lymphoma, Adult T-Cell; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1991 |
Characterization of a transgenic mouse line over-expressing the human ornithine decarboxylase gene.
Topics: Animals; Base Sequence; Brain; Gene Expression; Half-Life; Humans; Male; Mice; Mice, Transgenic; Molecular Sequence Data; Ornithine Decarboxylase; Polymerase Chain Reaction; Putrescine; RNA, Messenger; Spermidine; Spermine; Testis | 1991 |
Polyamines and the calcium paradox in rat hearts.
Topics: Animals; Calcium; Chromatography, High Pressure Liquid; Eflornithine; Egtazic Acid; Female; Heart; Myocardium; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Systole | 1991 |
Polyamine involvement in the secretion and action of TGF-alpha in hormone sensitive human breast cancer cells in culture.
Topics: Breast Neoplasms; Cell Division; Eflornithine; Estrogens; Humans; In Vitro Techniques; Neoplasms, Hormone-Dependent; Polyamines; Putrescine; Serum Albumin, Bovine; Spermidine; Spermine; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1991 |
Antimutagenic activities of naturally occurring polyamines in Chinese hamster ovary cells in vitro.
Topics: Animals; Antimutagenic Agents; Cell Division; CHO Cells; Cricetinae; Ficusin; Mitotic Index; Polyamines; PUVA Therapy; Sister Chromatid Exchange; Spermidine; Spermine; Ultraviolet Rays | 1991 |
The detection of spermine and spermidine in human in vitro fertilization supernatants and their relation to early embryo-associated suppressor activity.
Topics: Chromatography, High Pressure Liquid; Female; Fertilization in Vitro; Humans; Male; Spermidine; Spermine | 1991 |
Putrescine and spermidine uptake is regulated by proliferation and dexamethasone treatment in AR4-2J cells.
Topics: Animals; Biological Transport; Cell Division; Cell Line; Cells, Cultured; Dexamethasone; Eflornithine; Kinetics; Male; Pancreas; Pancreatic Neoplasms; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1991 |
Effect of alpha-difluoromethylornithine on the polyamine levels and proliferation in two transplantable tumours.
Topics: Animals; Cell Division; Cell Nucleus; Eflornithine; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred CBA; Microscopy, Electron; Neoplasm Transplantation; Organelles; Polyamines; Putrescine; Sarcoma, Experimental; Spermidine; Spermine | 1991 |
Phosphorylation and chromatin mechanics: the central importance of substrate conformation in determining the patterns of HL-60 nuclear phosphorylation.
Topics: Cell Line; Cell Nucleus; Chromatin; Deoxyribonuclease I; Electrophoresis, Polyacrylamide Gel; Nuclear Proteins; Phosphorylation; Spermidine; Spermine; Substrate Specificity | 1991 |
The effects of polyamines on the immunogenicity of polynucleotides.
Topics: Animals; Antibody Formation; DNA; DNA, Single-Stranded; Female; Immunization; Nucleic Acid Conformation; Polydeoxyribonucleotides; Rabbits; Spermidine; Spermine | 1991 |
Ifenprodil and SL 82.0715 as cerebral antiischemic agents. III. Evidence for antagonistic effects at the polyamine modulatory site within the N-methyl-D-aspartate receptor complex.
Topics: Adrenergic alpha-Antagonists; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Brain; Cells, Cultured; Drug Interactions; Female; Glycine; Male; N-Methylaspartate; Phencyclidine; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine; Spinal Cord | 1990 |
Polyamines regulate glycine interaction with the N-methyl-D-aspartate receptor.
Topics: Animals; Cerebral Cortex; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Male; Polyamines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine | 1990 |
Induction of ornithine decarboxylase in cerebral cortex by excitotoxin lesion of nucleus basalis: association with postsynaptic responsiveness and N-methyl-D-aspartate receptor activation.
Topics: Animals; Basal Ganglia; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Eflornithine; Enzyme Induction; Excitatory Amino Acid Antagonists; Glutamic Acid; Ibotenic Acid; Kainic Acid; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxazoles; Pentobarbital; Phosphatidylinositol Phosphates; Phosphatidylinositols; Putrescine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine; Substantia Innominata; Synapses | 1990 |
Polyamines and transglutaminase actions.
Topics: Animals; Male; Polyamines; Prostate; Putrescine; Rats; Seminal Vesicles; Spermidine; Spermine; Tissue Distribution; Transglutaminases | 1990 |
Restoration of the DNA binding activity of estrogen receptor in MRL-lpr/lpr mice by a polyamine biosynthesis inhibitor.
Topics: Animals; DNA; Down-Regulation; Eflornithine; Female; Lupus Erythematosus, Systemic; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Putrescine; Receptors, Estrogen; Spermidine; Spermine; Uterus | 1991 |
Characterization of human spermidine/spermine N1-acetyltransferase purified from cultured melanoma cells.
Topics: Acetyltransferases; Coenzyme A; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Enzyme Stability; Humans; Hydrolysis; Kinetics; Melanoma; Molecular Weight; Spermidine; Spermine; Tumor Cells, Cultured | 1991 |
Activation by spermine of citrate synthase from porcine heart.
Topics: Animals; Citrate (si)-Synthase; Citric Acid Cycle; Enzyme Activation; Myocardium; Putrescine; Spermidine; Spermine; Swine | 1991 |
Polyamine levels in healthy and tumor tissues of patients with colon adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Colon; Colonic Neoplasms; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Proteins; Spermidine; Spermine | 1991 |
Effect of dibutyltin dilaurate on regional brain polyamines in rats.
Topics: Animals; Anthelmintics; Body Weight; Brain; Female; Organotin Compounds; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1991 |
Selective cellular depletion of mitochondrial DNA by the polyamine analog N1,N12-bis(ethyl)spermine and its relationship to polyamine structure and function.
Topics: Animals; Antineoplastic Agents; Blotting, Southern; Cell Division; Cell Line, Transformed; DNA; DNA Damage; DNA, Mitochondrial; DNA, Neoplasm; DNA, Superhelical; Electrophoresis, Agar Gel; Fibroblasts; Leukemia L1210; Mice; Polyamines; Spermidine; Spermine; Structure-Activity Relationship; Time Factors | 1991 |
Effects of 2,4-dichlorophenoxyacetic acid on polyamine synthesis in Chinese hamster ovary cells.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Cells, Cultured; Cricetinae; Cricetulus; Culture Media; DNA; Kinetics; Ornithine Decarboxylase; Polyamines; Protein Biosynthesis; Putrescine; Spermidine; Spermine; Time Factors; Trypsin | 1991 |
Two new photoaffinity polyamines appear to alter the helical twist of DNA in nucleosome core particles.
Topics: Affinity Labels; Animals; Azides; Binding Sites; Cattle; DNA; Indicators and Reagents; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleosomes; Ornithine Decarboxylase; Polyamines; Saccharomyces cerevisiae; Spermidine; Spermine; Thymus Gland | 1991 |
Polyamine metabolism in Pneumocystis carinii.
Topics: Animals; Arginine; Eflornithine; Lung; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pentamidine; Pneumocystis; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1991 |
Polyamines favor DNA triplex formation at neutral pH.
Topics: DNA; Hydrogen-Ion Concentration; Kinetics; Nucleic Acid Conformation; Nucleic Acid Denaturation; Spermidine; Spermine | 1991 |
[Raised polyamines in erythrocytes of DMH administrated rats with colonic cancers and those relationship to tumor volume].
Topics: 1,2-Dimethylhydrazine; Animals; Colonic Neoplasms; Dimethylhydrazines; Erythrocytes; Male; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1991 |
Irreversible inhibition of S-adenosylmethionine decarboxylase in Plasmodium falciparum-infected erythrocytes: growth inhibition in vitro.
Topics: Adenosylmethionine Decarboxylase; Animals; Cells, Cultured; Chloroquine; Deoxyadenosines; Eflornithine; Erythrocytes; Humans; Plasmodium falciparum; Polyamines; Spermidine; Spermine | 1991 |
Seminal polyamines as agents of cervical carcinoma: production of aneuploidy in squamous epithelium.
Topics: Adult; Aneuploidy; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Cervix Uteri; Diamines; DNA, Neoplasm; Epithelium; Female; Humans; Male; Middle Aged; Polyamines; Semen; Spermidine; Spermine; Uterine Cervical Neoplasms | 1991 |
Arginine metabolism in rat enterocytes.
Topics: Animals; Arginine; Citrulline; Female; Intestinal Mucosa; Ornithine; Oxidation-Reduction; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Urea | 1991 |
Polyamine uptake, binding and release in rat brain.
Topics: Animals; Biogenic Polyamines; Brain Chemistry; In Vitro Techniques; Kinetics; Male; Membranes; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Synaptosomes | 1991 |
Polyamines in the anemia of end-stage renal disease.
Topics: Anemia; Bone Marrow; Colony-Forming Units Assay; Erythropoiesis; Erythropoietin; Humans; In Vitro Techniques; Kidney Failure, Chronic; Polyamines; Putrescine; Spermidine; Spermine | 1991 |
Condensation and precipitation of chromatin by multivalent cations.
Topics: Animals; Cations; Chemical Precipitation; Chromatin; Circular Dichroism; Cobalt; DNA; Electrophoresis, Polyacrylamide Gel; Liver; Magnesium; Polyamines; Rats; Solubility; Spermidine; Spermine; Thermodynamics | 1991 |
Spermidine or spermine is essential for the aerobic growth of Saccharomyces cerevisiae.
Topics: Adenosylmethionine Decarboxylase; Aerobiosis; Anaerobiosis; DNA Mutational Analysis; Genes, Fungal; Saccharomyces cerevisiae; Spermidine; Spermine | 1991 |
[Polyamine and middle-molecule peptide levels in patients with chronic myeloid leukemia during treatment].
Topics: Antineoplastic Agents; Drug Resistance; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasm Staging; Peptides; Plasmapheresis; Polyamines; Putrescine; Spermidine; Spermine | 1990 |
Putrescine decreases exploration of a black and white maze.
Topics: Animals; Biogenic Polyamines; Cerebral Cortex; Color; Cyclohexylamines; Exploratory Behavior; Injections, Intraperitoneal; Kidney Diseases; Male; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1990 |
Inhibition of adenylate cyclase activity by polyamines in human erythrocyte plasma membranes.
Topics: Adenylyl Cyclase Inhibitors; Arginine; Colforsin; Enzyme Activation; Erythrocyte Membrane; Glutamine; Humans; Lysine; Putrescine; Spermidine; Spermine | 1990 |
Experience affects cortical but not subcortical polyamines.
Topics: Animals; Biogenic Polyamines; Brain; Cerebellum; Cerebral Cortex; Eflornithine; Environment; Male; Medulla Oblongata; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1990 |
[The effect of Cu2+, Zn2+ cations and biogenic amines on the nuclear poly(ADP-ribose) polymerase activity in the rat brain].
Topics: Aging; Animals; Biogenic Polyamines; Brain; Cations, Divalent; Cell Nucleus; Copper; Enzyme Activation; In Vitro Techniques; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Spermidine; Spermine; Zinc | 1990 |
Regulation of the Na(+)-dependent and the Na(+)-independent polyamine transporters in renal epithelial cells (LLC-PK1).
Topics: Animals; Biological Transport; Carrier Proteins; Cell Line; Cell Membrane; Cells, Cultured; Chromatography, High Pressure Liquid; Cycloheximide; Dactinomycin; Eflornithine; Epithelial Cells; Epithelium; Kidney; Mitoguazone; Polyamines; Putrescine; Serum Albumin, Bovine; Sodium; Spermidine; Spermine; Swine | 1990 |
Acquisition of polyamines by the obligate intracytoplasmic bacterium Rickettsia prowazekii.
Topics: Animals; Biological Transport; Carboxy-Lyases; Cell Line; Cytoplasm; Mutation; Ornithine Decarboxylase; Polyamines; Putrescine; Rickettsia prowazekii; Spermidine; Spermine | 1990 |
Automated precolumn derivatization of amino acids, small peptides, brain amines and drugs with primary amino groups for reversed-phase high-performance liquid chromatography using naphthalenedialdehyde as the fluorogenic label.
Topics: Aldehydes; Amines; Amino Acids; Amphetamine; Animals; Antidepressive Agents; Baclofen; Brain Chemistry; Chromatography, High Pressure Liquid; Fluorescence; Fluvoxamine; Naphthalenes; Oximes; Peptides; Rats; Spermidine; Spermine; Tyramine | 1990 |
Mechanisms of lung polyamine accumulation in chronic hypoxic pulmonary hypertension.
Topics: Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Liver; Lung; Male; Ornithine Decarboxylase; Polyamines; Pulmonary Artery; Putrescine; Rats; Rats, Inbred Strains; Reference Values; Spermidine; Spermine; Time Factors | 1990 |
Characterization of the stimulatory and inhibitory effects of polyamines on [3H]N-(1-[thienyl]cyclohexyl) piperidine binding to the N-methyl-D-aspartate receptor ionophore complex.
Topics: Animals; Cerebral Cortex; Ionophores; Kinetics; Phencyclidine; Polyamines; Putrescine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine | 1990 |
Transport and metabolism of polyamines in human lymphocytes.
Topics: Amiloride; Biological Transport, Active; Cells, Cultured; Humans; Hydrogen-Ion Concentration; Kinetics; Lymphocytes; Ouabain; Polyamines; Putrescine; Sodium; Sodium-Potassium-Exchanging ATPase; Spermidine; Spermine; Vanadates | 1990 |
Polyamines stimulate the phosphorylation of phosphatidylinositol in rat mast cell granules.
Topics: Animals; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Male; Mast Cells; Phosphatidylinositols; Phosphorylation; Polyamines; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1990 |
Characterization of polyamines having agonist, antagonist, and inverse agonist effects at the polyamine recognition site of the NMDA receptor.
Topics: Animals; Binding Sites; Cells, Cultured; Diamines; Dibenzocycloheptenes; Dizocilpine Maleate; Electric Conductivity; Glutamates; Glycine; Hippocampus; Kinetics; Magnesium; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine; Zinc | 1990 |
The polyamine spermine affects omega-conotoxin binding and function at N-type voltage-sensitive calcium channels.
Topics: Animals; Calcium Channels; Dose-Response Relationship, Drug; Hippocampus; Iodine Radioisotopes; Male; Muscle Contraction; Muscle, Smooth; omega-Conotoxin GVIA; Peptides, Cyclic; Rats; Spermidine; Spermine; Synaptosomes; Vas Deferens | 1990 |
Stimulation of Na+/K(+)-ATPase activity by polyamines in the rat renal medullary cells of the thick ascending limb of Henle's loop.
Topics: Animals; Arginine Vasopressin; Dose-Response Relationship, Drug; Female; Histocytochemistry; Kidney; Kidney Medulla; Loop of Henle; Organ Culture Techniques; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Spermidine; Spermine; Stimulation, Chemical | 1990 |
Stimulation and inhibition of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced strand breaks and interstrand cross-linking in Col E1 plasmid deoxyribonucleic acid by polyamines and inorganic cations.
Topics: Carmustine; Cations; Cobalt; Cross-Linking Reagents; DNA, Bacterial; Escherichia coli; Magnesium; Methylnitrosourea; Plasmids; Polyamines; Putrescine; Sodium; Spermidine; Spermine | 1990 |
Effect of polyamines on the activity of malarial alpha-like DNA polymerase.
Topics: Animals; Cattle; Cell Line, Transformed; Dactinomycin; DNA; DNA Polymerase II; Erythrocytes; Genes, ras; Humans; Magnesium; Plasmodium falciparum; Polyamines; Putrescine; Spermidine; Spermine | 1990 |
Colonic polyamine content and ornithine decarboxylase activity as markers for adenomas.
Topics: Aged; Biogenic Polyamines; Biomarkers, Tumor; Colonic Polyps; Colorectal Neoplasms; Female; Humans; Intestinal Mucosa; Male; Mass Screening; Middle Aged; Ornithine Decarboxylase; Precancerous Conditions; Putrescine; Spermidine; Spermine | 1990 |
Treatment of chloroquine-resistant malaria with esters of cephalotaxine: homoharringtonine.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Harringtonines; Homoharringtonine; Malaria; Mice; Plasmodium falciparum; Plasmodium yoelii; Putrescine; Spermidine; Spermine | 1990 |
The role of polyamines as a marker of tumor progression and regression in experimental tumors.
Topics: Animals; Biomarkers, Tumor; Carcinoma, Ehrlich Tumor; Cell Division; Cell Transformation, Neoplastic; Erythrocytes; Female; Mice; Polyamines; Putrescine; Spermidine; Spermine; Vitamin A | 1990 |
Regulation of polyamine biosynthesis by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
Topics: Animals; Ascites; Body Weight; Eflornithine; Female; Liver; Mice; Mice, Inbred Strains; Organ Size; Polyamines; Polychlorinated Dibenzodioxins; Putrescine; Spermidine; Spermine; Spleen; Thymus Gland | 1990 |
N1N8-bis(gamma-glutamyl)spermidine cross-linking in epidermal-cell envelopes. Comparison of cross-link levels in normal and psoriatic cell envelopes.
Topics: Amino Acids; Cross-Linking Reagents; Dipeptides; Epidermis; Humans; Molecular Structure; Polyamines; Psoriasis; Skin; Spermidine; Spermine | 1990 |
A role for polyamines in glucose-stimulated insulin-gene expression.
Topics: Animals; Cell Nucleus; Culture Techniques; Cycloheximide; Dactinomycin; Eflornithine; Gene Expression; Glucose; Insulin; Islets of Langerhans; Male; Mice; Mitoguazone; Polyamines; RNA, Messenger; Spermidine; Spermine | 1990 |
Polyamine involvement in basal and estradiol-stimulated insulin-like growth factor I secretion and action in breast cancer cells in culture.
Topics: Antibodies, Monoclonal; Breast Neoplasms; Cell Transformation, Neoplastic; Eflornithine; Estradiol; Humans; Insulin-Like Growth Factor I; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1990 |
Polyamine depletion and growth inhibition of Cryptococcus neoformans by alpha-difluoromethylornithine and cyclohexylamine.
Topics: Cryptococcus neoformans; Cyclohexylamines; Dose-Response Relationship, Drug; Eflornithine; Humans; Polyamines; Putrescine; Spermidine; Spermine | 1990 |
Effect of sinefungin on macromolecular biosynthesis and cell cycle of Plasmodium falciparum.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Autoradiography; DNA, Protozoan; Electrophoresis, Polyacrylamide Gel; Molecular Structure; Plasmodium falciparum; Polyamines; Protozoan Proteins; Spermidine; Spermine | 1990 |
Urinary polyamine and metabolite excretion by children with Zellweger's syndrome.
Topics: Amino Acids, Diamino; Child, Preschool; Female; Humans; Hydrolysis; Infant; Infant, Newborn; Polyamines; Spermidine; Spermine; Zellweger Syndrome | 1990 |
[Ornithine decarboxylase activity and polyamine contents in 1,2-dimethylhydrazine-induced carcinogenesis of the intestines in rats].
Topics: 1,2-Dimethylhydrazine; Animals; Dimethylhydrazines; Intestinal Mucosa; Intestinal Neoplasms; Intestine, Large; Intestine, Small; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Spermidine; Spermine; Time Factors | 1990 |
[Detection of polyamines by a new enzymatic differential assay. (7) Fundamental study on a new enzymatic differential assay of tissue polyamines].
Topics: Biogenic Polyamines; Biological Assay; Chromatography, High Pressure Liquid; Diamines; Humans; Kidney; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Spermine | 1990 |
[Detection of polyamines by a new enzymatic differential assay. (8) Studies on tissue polyamine concentrations in patients with genitourinary malignant diseases].
Topics: Biogenic Polyamines; Biological Assay; Carcinoma, Renal Cell; Diamines; DNA, Neoplasm; Humans; Kidney; Kidney Neoplasms; Spermidine; Spermine; Ureter; Ureteral Neoplasms; Urinary Bladder; Urinary Bladder Neoplasms; Urologic Neoplasms | 1990 |
Concentration-dependent effects of natural polyamines on peptide chain initiation and elongation in a cell-free system of protein synthesis.
Topics: Animals; Cell-Free System; Electrophoresis, Polyacrylamide Gel; Globins; Male; Mice; Mice, Inbred C3H; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; RNA, Messenger; Spermidine; Spermine; Tobacco Mosaic Virus; Viral Proteins | 1990 |
[Determination of polyamine constituents in radix ginseng by HPLC].
Topics: Chromatography, High Pressure Liquid; Panax; Plants, Medicinal; Polyamines; Putrescine; Spermidine; Spermine | 1990 |
Polyamines in colorectal cancer. Evaluation of polyamine concentrations in the colon tissue, serum, and urine of 50 patients with colorectal cancer.
Topics: Antigens, Tumor-Associated, Carbohydrate; Cadaverine; Carcinoembryonic Antigen; Colon; Colonic Neoplasms; Female; Humans; Male; Middle Aged; Polyamines; Putrescine; Rectal Neoplasms; Spermidine; Spermine | 1990 |
Polyamines improve Ca2+ transport system of the yeast mitochondria.
Topics: Biological Transport, Active; Cadaverine; Calcium; Mitochondria; Putrescine; Saccharomycetales; Spermidine; Spermine | 1990 |
Inhibitory effects of spermine and spermidine on muscle calpain II.
Topics: Animals; Calcium-Binding Proteins; Calpain; Chickens; Cricetinae; Gizzard, Avian; Muscles; Spermidine; Spermine | 1990 |
Polyamine concentrations in pancreatic tissue, serum, and urine of patients with pancreatic cancer.
Topics: Antigens, Tumor-Associated, Carbohydrate; Biogenic Polyamines; Cadaverine; Carcinoembryonic Antigen; Female; Humans; Male; Middle Aged; Pancreas; Pancreatic Neoplasms; Putrescine; Spermidine; Spermine | 1990 |
Enhanced binding of lupus sera to the polyamine-induced left-handed Z-DNA form of polynucleotides.
Topics: Autoantibodies; DNA; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; Lupus Erythematosus, Systemic; Polyamines; Polynucleotides; Spermidine; Spermine | 1990 |
Towards microfluorometric quantitation of polyamines in situ. Relationship between cellular polyamine concentration and fluorescence yield of the formaldehyde fluorescamine method.
Topics: Breast Neoplasms; Cytophotometry; Fluorescamine; Fluorescence; Formaldehyde; HeLa Cells; Humans; Methods; o-Phthalaldehyde; Spermidine; Spermine; Tumor Cells, Cultured | 1990 |
Immunosuppressive activity and polyamine levels of seminal plasma in azo-ospermic, oligospermic, and normospermic men.
Topics: Graft vs Host Reaction; Humans; Immune Tolerance; Lymphocyte Activation; Male; Oligospermia; Rosette Formation; Semen; Spermidine; Spermine | 1990 |
Effect of N1,N14-bis(ethyl)homospermine on the growth of U-87 MG and SF-126 human brain tumor cells.
Topics: Brain Neoplasms; Cell Division; Humans; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1990 |
Bioamines and proteins in the saliva and salivary glands of Palaearctic blackflies (Diptera: Simuliidae).
Topics: Animals; Biogenic Amines; Chromatography, Gel; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Esterases; Female; Histamine; Histocytochemistry; Putrescine; Saliva; Salivary Glands; Salivary Proteins and Peptides; Simuliidae; Spermidine; Spermine | 1990 |
Modulation by polyamines of DNA-dependent DNA polymerase activity from human serum.
Topics: DNA; DNA Polymerase I; Enzyme Activation; Histamine; Humans; Kinetics; Magnesium Chloride; Poly dA-dT; Polyamines; Polydeoxyribonucleotides; Putrescine; Spermidine; Spermine; Templates, Genetic | 1990 |
Determination of polyamines in urine of normal human and cancer patients by capillary gas chromatography.
Topics: Adolescent; Adult; Aged; Chromatography, Gas; Female; Humans; Male; Middle Aged; Neoplasms; Polyamines; Putrescine; Spermidine; Spermine | 1990 |
A study on the vital reaction in wounded skin: simultaneous determination of histamine and polyamines in injured rat skin by high-performance liquid chromatography.
Topics: Animals; Biogenic Polyamines; Calibration; Chromatography, High Pressure Liquid; Histamine; Male; Postmortem Changes; Putrescine; Rats; Rats, Inbred Strains; Skin; Spermidine; Spermine; Wound Healing; Wounds, Penetrating | 1990 |
Dual mechanisms of inhibition of DNA synthesis by triciribine.
Topics: Animals; Antineoplastic Agents; DNA Polymerase I; DNA Primase; DNA Replication; DNA, Neoplasm; Kinetics; Leukemia L1210; Mice; Putrescine; Ribonucleosides; RNA Nucleotidyltransferases; Spermidine; Spermine; Thymidine; Tumor Cells, Cultured | 1990 |
[Antiaggregatory and anticoagulant effects of oligoamines. 12. Alkyl- and arylalkyl- derivatives of putrescine, spermidine and spermine].
Topics: Anticoagulants; Chemical Phenomena; Chemistry; Humans; In Vitro Techniques; Platelet Aggregation Inhibitors; Putrescine; Spermidine; Spermine | 1990 |
Androgen regulation of polyamine synthesis in seminal vesicle and in different lobes of the rat prostate.
Topics: Animals; Male; Orchiectomy; Polyamines; Prostate; Putrescine; Rats; Rats, Inbred Strains; Seminal Vesicles; Spermidine; Spermine; Testosterone; Time Factors | 1990 |
Red blood cell polyamine level changes following heart transplantation in man.
Topics: Chromatography, High Pressure Liquid; Erythrocytes; Female; Heart Transplantation; Humans; Male; Spermidine; Spermine | 1990 |
Changes in serum and hepatic polyamine concentrations after 30%, 70% and 90% partial hepatectomy in rats.
Topics: Animals; DNA; Hepatectomy; Liver; Liver Regeneration; Male; Organ Size; Polyamines; Proteins; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Time Factors | 1990 |
Urinary excretion of polyamines: importance of circadian rhythm, age, sex, menstrual cycle, weight, and creatinine excretion.
Topics: Adult; Aging; Body Weight; Chromatography; Circadian Rhythm; Creatinine; Female; Humans; Male; Menstrual Cycle; Middle Aged; Polyamines; Putrescine; Spermidine; Spermine | 1990 |
Methylglyoxal bis(guanylhydrazone) elimination of polyamine effects on protein synthesis.
Topics: Animals; Cell-Free System; DNA; Escherichia coli; Kinetics; Mitoguazone; Peptides; Poly U; Proteins; Rabbits; RNA; RNA-Dependent RNA Polymerase; RNA, Ribosomal; Spermidine; Spermine | 1985 |
Stimulation by the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine of rat hepatic polyamine biosynthesis in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Female; Liver; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Theophylline | 1985 |
[Determination of free polyamines in blood].
Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; Polyamines; Spermidine; Spermine | 1985 |
[Therapy with inhibitors of polyamine biosynthesis in refractory prostatic carcinoma. An experimental and clinical study].
Topics: Adenocarcinoma; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Carboxy-Lyases; Carcinoma; Eflornithine; Estrogens; Humans; Male; Mitoguazone; Neoplasm Metastasis; Ornithine; Ornithine Decarboxylase Inhibitors; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatitis; Putrescine; Rats; Spermidine; Spermine | 1985 |
[Detection of urinary polyamine by a new enzymatic differential assay. (III). Studies on urinary polyamines in patients with malignant genitourinary diseases].
Topics: Diamines; Humans; Kidney Neoplasms; Male; Polyamines; Prostatic Hyperplasia; Prostatic Neoplasms; Spermidine; Spermine; Urinary Bladder Neoplasms; Urogenital Neoplasms | 1986 |
Role of polyamines in experience-dependent brain plasticity.
Topics: Animals; Body Weight; Brain; Cerebral Cortex; DNA; Eflornithine; Male; Neuronal Plasticity; Organ Size; Putrescine; Rats; Rats, Inbred Strains; RNA; Spermidine; Spermine | 1987 |
Polyamine metabolism in an obligately alkalophilic Bacillus alcalophilus that grows at pH 11.0.
Topics: Arginine; Bacillus; Biological Transport, Active; Chromatography, High Pressure Liquid; Escherichia coli; Gramicidin; Hydrogen-Ion Concentration; Kinetics; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Sodium; Spermidine; Spermine; Valinomycin | 1988 |
Mechanisms of the trophic actions of bombesin on the pancreas.
Topics: Animals; Bombesin; Cholecystokinin; DNA; Hyperplasia; Pancreas; Polyamines; Proglumide; Proteins; Putrescine; Rats; Receptors, Cholecystokinin; RNA; Spermidine; Spermine | 1988 |
Role of polyamines in the synthesis of RNA in mycobacteria.
Topics: DNA; DNA-Directed RNA Polymerases; Mycobacteriaceae; Polyamines; Putrescine; RNA; Spermidine; Spermine | 1987 |
Possible roles of beta-elimination and delta-elimination reactions in the repair of DNA containing AP (apurinic/apyrimidinic) sites in mammalian cells.
Topics: Animals; Apurinic Acid; Bacteriophage phi X 174; Binding Sites; Deoxyribonuclease IV (Phage T4-Induced); DNA Ligases; DNA Polymerase I; DNA Repair; DNA Replication; DNA-(Apurinic or Apyrimidinic Site) Lyase; Electrophoresis, Polyacrylamide Gel; Endodeoxyribonucleases; Histones; Liver; Polynucleotides; Rats; Spermidine; Spermine | 1988 |
[The fractional composition of polyamines in the urine of normal subjects].
Topics: Adolescent; Adult; Circadian Rhythm; Female; Humans; Male; Middle Aged; Putrescine; Reference Values; Spermidine; Spermine | 1988 |
Regulation of band 3 mobilities in erythrocyte ghost membranes by protein association and cytoskeletal meshwork.
Topics: Affinity Labels; Anion Exchange Protein 1, Erythrocyte; Cytoskeleton; Diffusion; Electrophoresis, Polyacrylamide Gel; Eosine Yellowish-(YS); Erythrocyte Membrane; Humans; Macromolecular Substances; Mathematics; Membrane Proteins; Photometry; Putrescine; Sodium Chloride; Spermidine; Spermine | 1988 |
Spermidine uptake by type II pulmonary epithelial cells in primary culture.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Blood; Calcimycin; Cells, Cultured; Epithelium; Gramicidin; Kinetics; Lung; Male; Mitoguazone; Paraquat; Putrescine; Rats; Rats, Inbred Strains; Sodium; Spermidine; Spermine; Temperature | 1989 |
Polyamine effects on DNA-directed RNA polymerases in the ciliate Tetrahymena thermophila. In vivo- and in vitro-experiments suggesting highly specific regulative interactions.
Topics: Amanitins; Animals; Cell Nucleus; DNA-Directed RNA Polymerases; Electrophoresis, Agar Gel; Kinetics; Putrescine; RNA; Spermidine; Spermine; Tetrahymena; Transcription, Genetic | 1989 |
Substance P and vasoactive intestinal peptide influence polyamine metabolism in salivary glands of the rat.
Topics: Animals; Bethanechol; Bethanechol Compounds; Infusions, Intravenous; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Salivary Glands; Spermidine; Spermine; Substance P; Vasoactive Intestinal Peptide | 1989 |
Recognition of Z-RNA and Z-DNA determinants by polyamines in solution: experimental and theoretical studies.
Topics: Binding Sites; Buffers; DNA; Immunoglobulin G; Models, Molecular; Nucleic Acid Conformation; Polyamines; RNA; Sodium; Spermidine; Spermine | 1988 |
Molecular basis for potentiation of bleomycin-mediated degradation of DNA by polyamines. Experimental and molecular mechanical studies.
Topics: Base Sequence; Bleomycin; DNA; Gene Amplification; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Nucleic Acid Denaturation; Polyamines; Putrescine; Spermidine; Spermine | 1989 |
Polyamine-dependent growth and calmodulin-regulated induction of ornithine decarboxylase.
Topics: Animals; Calcimycin; Calcium; Calmodulin; Cell Division; Cell Line; Dimethyl Sulfoxide; DNA; DNA Replication; Enzyme Induction; Flow Cytometry; Intestine, Small; Kinetics; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine | 1989 |
Swelling of the Golgi apparatus and decrease of galactosyltransferase in polyamine-deficient bovine lymphocytes and epithelium of mouse small intestine.
Topics: Animals; Cattle; Cells, Cultured; Concanavalin A; Eflornithine; Epithelium; Galactosyltransferases; Golgi Apparatus; Intestinal Mucosa; Intestine, Small; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Microscopy, Electron; Mitoguazone; Polyamines; Spermidine; Spermine | 1989 |
Cellular characterization of a new irreversible inhibitor of S-adenosylmethionine decarboxylase and its use in determining the relative abilities of individual polyamines to sustain growth and viability of L1210 cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cell Division; Cell Survival; Deoxyadenosines; Eflornithine; Leukemia L1210; Mice; Polyamines; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1989 |
Trypanosoma brucei brucei: regulation of ornithine decarboxylase in procyclic forms and trypomastigotes.
Topics: Animals; Cycloheximide; Dactinomycin; Eflornithine; Enzyme Induction; Half-Life; Male; Ornithine Decarboxylase; Putrescine; Rats; Spermidine; Spermine; Trypanosoma brucei brucei | 1989 |
Polyamines differentially modulate the transcription of growth-associated genes in human colon carcinoma cells.
Topics: Actins; Cell Division; Cell Line; Colonic Neoplasms; Eflornithine; Genes; Histones; Humans; Ornithine Decarboxylase; Proto-Oncogenes; Spermidine; Spermine; Transcription, Genetic | 1989 |
Polyamine transport systems in the LLC-PK1 renal epithelial established cell line.
Topics: Animals; Biogenic Polyamines; Biological Transport; Cell Differentiation; Cell Division; Cell Line; Eflornithine; Epithelial Cells; Epithelium; Kidney; Putrescine; Sodium; Spermidine; Spermine | 1989 |
Excretion of acetylated and free polyamines by polyamine depleted Chinese hamster ovary cells.
Topics: Animals; Biogenic Polyamines; Cell Division; Cell Line; Eflornithine; Putrescine; Spermidine; Spermine | 1989 |
Paraquat is not accumulated in B16 tumor cells by the polyamine transport system.
Topics: Biological Transport; Dose-Response Relationship, Drug; Eflornithine; Kinetics; Melanoma, Experimental; Paraquat; Polyamines; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1989 |
Inhibitory action of alpha-difluoromethylornithine on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat urinary bladder carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Drug Administration Schedule; Eflornithine; Male; Neoplasms, Experimental; Putrescine; Rats; Rats, Inbred F344; Spermidine; Spermine; Time Factors; Urinary Bladder Neoplasms | 1989 |
Polyamines in lymphocytes from patients infected by human immunodeficiency virus.
Topics: Acetyltransferases; Acquired Immunodeficiency Syndrome; Amine Oxidase (Copper-Containing); Biogenic Polyamines; HIV Antibodies; HIV-1; Humans; In Vitro Techniques; Lymphocytes; Putrescine; Spermidine; Spermine | 1989 |
Acetylated polyamines in lungs from rats with monocrotaline-induced pneumotoxicity.
Topics: Acetylation; Acetyltransferases; Animals; Biogenic Polyamines; Cytosol; Dose-Response Relationship, Drug; Lung; Lung Diseases; Male; Monocrotaline; Putrescine; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Spermidine; Spermine; Time Factors | 1989 |
Role of ornithine decarboxylase and polyamines in camostate (Foy-305)-induced pancreatic growth in rats.
Topics: Animals; Cholecystokinin; Eflornithine; Esters; Gabexate; Guanidines; Kinetics; Male; Ornithine Decarboxylase; Pancreas; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1989 |
Modulation of growth gene expression by selective alteration of polyamines in human colon carcinoma cells.
Topics: Adenosine; Blotting, Northern; Cell Division; Cell Line; Colonic Neoplasms; Eflornithine; Gene Expression Regulation, Neoplastic; Humans; Polyamines; Proto-Oncogenes; Putrescine; RNA, Messenger; Spermidine; Spermine; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
The effect of spermine, spermidine and kallikrein on the triple adenosine triphosphatase enzyme activity of spermatozoa in males with oligoasthenozoospermia.
Topics: Adenosine Triphosphatases; Humans; Kallikreins; Male; Oligospermia; Sperm Motility; Spermatozoa; Spermidine; Spermine | 1989 |
Topological complexes between DNA and topoisomerase II and effects of polyamines.
Topics: Amsacrine; Animals; DNA Topoisomerases, Type II; DNA, Viral; Kinetics; Leukemia L1210; Mice; Protein Binding; Simian virus 40; Spermidine; Spermine | 1989 |
Effects of spermine and spermidine on the inorganic pyrophosphatase of Streptococcus faecalis. Interactions between polyamines and inorganic pyrophosphate.
Topics: Enterococcus faecalis; Inorganic Pyrophosphatase; Magnesium; Pyrophosphatases; Spermidine; Spermine | 1989 |
[Polyamines stimulate the phosphorylation of phosphatidylinositol in rat mast cell granules].
Topics: Animals; In Vitro Techniques; Mast Cells; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphorylation; Rats; Spermidine; Spermine; Stimulation, Chemical | 1989 |
Efficacy and toxicity of N,N',N",N"'-tetra(2,3,4-trihydroxybenzoyl)-spermine for decorporation of 239Pu from mice.
Topics: Animals; Bone and Bones; Chelating Agents; Kidney; Liver; Male; Mice; Pentetic Acid; Plutonium; Spermidine; Spermine | 1989 |
Inhibition of X-ray-induced DNA strand break repair in polyamine-depleted HeLa cells.
Topics: DNA Repair; DNA, Neoplasm; Eflornithine; HeLa Cells; Humans; Mitoguazone; Polyamines; Putrescine; Spermidine; Spermine | 1989 |
Polyamines in the small intestine of rats after whole-body irradiation.
Topics: Animals; Female; Intestine, Small; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Whole-Body Irradiation | 1989 |
Polyamine biosynthesis in the developing rabbit palate.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; DNA; Female; Gestational Age; Ornithine Decarboxylase; Palate; Polyamines; Pregnancy; Protein Biosynthesis; Putrescine; Rabbits; RNA; Spermidine; Spermine | 1985 |
Active transport and metabolic characteristics of polyamines in the rat lens.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Binding, Competitive; Biological Transport, Active; Kinetics; Lens, Crystalline; Male; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermidine Synthase; Spermine; Spermine Synthase | 1989 |
Polyamine levels in red blood cells from patient groups of different sex and age.
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, High Pressure Liquid; Erythrocytes; Female; Humans; Male; Middle Aged; Polyamines; Reference Values; Regression Analysis; Spermidine; Spermine | 1989 |
Regulation of eukaryotic initiation factor-2B activity by polyamines and amino acid starvation in rabbit reticulocyte lysate.
Topics: Amino Acids; Animals; Cell-Free System; Cycloheximide; Eukaryotic Initiation Factor-2; Heme; Kinetics; Phosphorylation; Rabbits; Reticulocytes; Spermidine; Spermine | 1989 |
Polyamines induce precocious development in rats. Possible interaction with growth factors.
Topics: Animals; Behavior, Animal; Biogenic Polyamines; Female; Growth Substances; Male; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1989 |
Hormonal control of polyamine pools in experimental breast cancer in vivo: correlation with estrogen and progesterone receptor levels.
Topics: Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Ovariectomy; Perphenazine; Prolactin; Putrescine; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Spermidine; Spermine; Time Factors | 1989 |
Spermidine uptake by type II pneumocytes: interactions of amine uptake pathways.
Topics: Animals; Biological Transport; Cells, Cultured; Choline; DNA; Epithelial Cells; Epithelium; Kinetics; Lithium; Lung; Male; Mitoguazone; Paraquat; Putrescine; Rats; Rats, Inbred Strains; Sodium; Spermidine; Spermine; Time Factors | 1989 |
Polyamines and other accessory sex gland secretions in human seminal plasma 8 years after vasectomy.
Topics: Acid Phosphatase; Adult; Aged; Citrates; Citric Acid; Cross-Sectional Studies; Genitalia, Male; Humans; Magnesium; Male; Middle Aged; Postoperative Period; Prostate; Putrescine; Semen; Spermidine; Spermine; Vasectomy; Zinc | 1989 |
A monoclonal antibody-based immunoassay for the polyamines spermine and spermidine.
Topics: Antibodies, Monoclonal; Enzyme-Linked Immunosorbent Assay; Immunoassay; Radioimmunoassay; Spermidine; Spermine | 1989 |
Polyamines, molecules necessary for cell division, colocalize with peptide growth factors.
Topics: Animals; Cell Division; Cytoplasmic Granules; Epidermal Growth Factor; Female; Growth Hormone; Immunohistochemistry; Islets of Langerhans; Male; Mice; Mice, Inbred BALB C; Pituitary Gland, Anterior; Platelet-Derived Growth Factor; Polyamines; Rats; Rats, Inbred Strains; Spermidine; Spermine; Submandibular Gland | 1989 |
Polyamines in rat adipocytes: their localization and their effects on the insulin receptor binding.
Topics: Adipose Tissue; Animals; Biogenic Polyamines; Chromatography, High Pressure Liquid; Fluorescent Antibody Technique; Immunoenzyme Techniques; In Vitro Techniques; Male; Putrescine; Rats; Rats, Inbred Strains; Receptor, Insulin; Spermidine; Spermine | 1989 |
Regulation of Saccharomyces cerevisiae ornithine decarboxylase expression in response to polyamine.
Topics: Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Genes, Fungal; Genotype; Kinetics; Ornithine Decarboxylase; Polyamines; Putrescine; RNA, Messenger; Saccharomyces cerevisiae; Spermidine; Spermine; Transcription, Genetic | 1989 |
Dietary protein enhanced mammary ornithine decarboxylase activity and tumorigenesis in rats.
Topics: Adenocarcinoma; Animals; Dietary Proteins; Epithelium; Female; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Ornithine Decarboxylase; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1989 |
Polyamine metabolism in Setaria cervi, the bovine filarial worm.
Topics: Adenosylmethionine Decarboxylase; Animals; Buffaloes; Chromatography, High Pressure Liquid; Filarioidea; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Polyamines; Putrescine; Setariasis; Spermidine; Spermine | 1989 |
Phase I study of methylacetylenic putrescine, an inhibitor of polyamine biosynthesis.
Topics: Adult; Aged; Alkynes; Antineoplastic Agents; Diamines; Drug Evaluation; Female; Humans; Male; Middle Aged; Neoplasms; Polyamines; Putrescine; Reference Values; Spermidine; Spermine | 1989 |
Polyamine levels as biomarkers of injury response in polytrauma victims.
Topics: Adult; Biomarkers; Female; Humans; Male; Polyamines; Proteins; Putrescine; Reference Values; Spermidine; Spermine; Wounds and Injuries | 1989 |
Red blood cell polyamines as a diagnostic indicator of glioma presence and recurrence.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Child; Child, Preschool; Female; Glioma; Humans; Male; Middle Aged; Spermidine; Spermine | 1989 |
[A decrease in the level of unscheduled DNA synthesis in preparations of irradiated rat hepatocyte nuclei under the effect of polyamines].
Topics: Animals; Calcium; Cell Nucleus; Chromatin; DNA Repair; Gamma Rays; Liver; Male; Nucleic Acid Synthesis Inhibitors; Polyamines; Rats; Rats, Inbred Strains; Spermidine; Spermine; Ultraviolet Rays | 1989 |
Urinary excretion of N1-acetylspermidine and other acetylated and free polyamines in the 1,2-dimethylhydrazine model of experimental rat colon cancer.
Topics: 1,2-Dimethylhydrazine; Acetylation; Animals; Biogenic Polyamines; Biomarkers, Tumor; Colonic Neoplasms; Dimethylhydrazines; Male; Predictive Value of Tests; Putrescine; Rats; Spermidine; Spermine | 1989 |
Changes in polyamine concentrations in amygdaloid-kindled rats.
Topics: Amygdala; Animals; Electric Stimulation; Kindling, Neurologic; Kinetics; Male; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1989 |
Determination of polyamines by precolumn derivatization with 9-fluorenylmethyl chloroformate and reverse-phase high-performance liquid chromatography.
Topics: Animals; Biogenic Polyamines; Chromatography, High Pressure Liquid; Fluorenes; Ganglia, Spinal; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1989 |
Effects of S-adenosyl-1,8-diamino-3-thio-octane and S-methyl-5'-methylthioadenosine on polyamine synthesis in Ehrlich ascites-tumour cells.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Carcinoma, Ehrlich Tumor; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermidine Synthase; Spermine; Spermine Synthase; Thionucleosides; Tumor Cells, Cultured | 1989 |
[Ornithine decarboxylase activity and polyamine levels in human thyroid tumor tissue].
Topics: Adenoma; Adolescent; Adult; Aged; Biogenic Polyamines; Carcinoma; Carcinoma, Papillary; Child; Female; Humans; Male; Middle Aged; Ornithine Decarboxylase; Putrescine; Reference Values; Spermidine; Spermine; Thyroid Neoplasms | 1989 |
Hyperthermia, polyamine depletion, and inhibition of X-ray-induced DNA strand break repair.
Topics: Biogenic Polyamines; DNA Damage; DNA Repair; DNA, Single-Stranded; HeLa Cells; Hot Temperature; Humans; Putrescine; Spermidine; Spermine | 1989 |
Major increases in spermidine/spermine-N1-acetyltransferase activity by spermine analogues and their relationship to polyamine depletion and growth inhibition in L1210 cells.
Topics: Acetyltransferases; Animals; Cell Division; Cell Line; Cell Survival; Dogs; Humans; Kinetics; Leukemia L1210; Mice; Polyamines; Spermidine; Spermine; Tumor Cells, Cultured | 1989 |
Polyamine addition to preparation media induces chromatin condensation, irreversibly at low ionic strength.
Topics: Animals; Chickens; Chromatin; Erythrocytes; Kinetics; Magnesium Chloride; Spectrum Analysis; Spermidine; Spermine | 1989 |
The effects of some polyamines on putative behavioural indices of mesolimbic versus striatal dopaminergic function.
Topics: Amphetamine; Animals; Behavior, Animal; Corpus Striatum; Injections, Intraventricular; Limbic System; Male; Mesencephalon; Mice; Mice, Inbred Strains; Motor Activity; Nucleus Accumbens; Polyamines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spermidine; Spermine; Stereotyped Behavior; Synaptic Transmission | 1987 |
Regulation of the dephosphorylation of phosphorylase A by glucose, AMP and polyamines.
Topics: Adenosine Monophosphate; Animals; Caffeine; Dose-Response Relationship, Drug; Enzyme Activation; Glucose; Liver; Muscles; Phosphoprotein Phosphatases; Phosphorylase a; Phosphorylases; Phosphorylation; Polyamines; Protein Phosphatase 1; Putrescine; Rabbits; Spermidine; Spermine; Temperature | 1988 |
Polyamines control human chorionic gonadotropin production in the JEG-3 choriocarcinoma cell.
Topics: Bucladesine; Cell Division; Choriocarcinoma; Chorionic Gonadotropin; Eflornithine; Humans; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; RNA, Messenger; Spermidine; Spermine; Tumor Cells, Cultured | 1988 |
Polyamines differentially inhibit cyclic AMP-dependent protein kinase-mediated phosphorylation in the brain of the tobacco hornworm, Manduca sexta.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Triphosphate; Animals; Brain; Calcium; Calmodulin; Caseins; Cyclic AMP; Histones; Lepidoptera; Moths; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Pupa; Spermidine; Spermine; Subcellular Fractions; Tissue Distribution | 1988 |
Polyamines stimulate the activity of glycogen synthase (casein) kinase-1 from bovine kidney and different rat tissues.
Topics: Animals; Calcineurin; Calmodulin-Binding Proteins; Casein Kinases; Cattle; Enzyme Activation; Glycogen Synthase; Heparin; Kidney; Liver; Magnesium; Male; Phosphoprotein Phosphatases; Phosphorylation; Phosvitin; Polyamines; Protein Kinases; Putrescine; Rats; Spermidine; Spermine; Testis | 1988 |
Effects of alpha-difluoromethylornithine on polyamine biosynthesis and tyrosine hydroxylase induction in the adrenal gland of the rat subjected to stress or apomorphine.
Topics: Adrenal Glands; Animals; Apomorphine; Cold Temperature; Eflornithine; Enzyme Induction; Male; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Restraint, Physical; Spermidine; Spermine; Stress, Physiological; Tyrosine 3-Monooxygenase | 1985 |
Presence of di- and polyamines covalently bound to protein in rat liver.
Topics: Animals; Chromatography, Ion Exchange; gamma-Glutamylcyclotransferase; Glutamine; Kidney; Liver; Male; Peptide Hydrolases; Polyamines; Protein Processing, Post-Translational; Proteins; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Testis | 1985 |
Evidence against putrescine and polyamines as endogenous mediators of fever.
Topics: Animals; Eflornithine; Endotoxins; Fever; Ornithine; Polyamines; Putrescine; Rabbits; Shigella dysenteriae; Spermidine; Spermine | 1985 |
Early stimulation of polyamine biosynthesis during promotion by phenobarbital of diethylnitrosamine-induced rat liver carcinogenesis. The effects of variations of the S-adenosyl-L-methionine cellular pool.
Topics: 2-Acetylaminofluorene; Animals; Diethylnitrosamine; Enzyme Induction; gamma-Glutamyltransferase; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Ornithine Decarboxylase; Phenobarbital; Polyamines; Putrescine; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Spermidine; Spermine | 1985 |
Ornithine decarboxylase, transglutaminase, diamine oxidase and total diamines and polyamines in maternal liver and kidney throughout rat pregnancy.
Topics: Amine Oxidase (Copper-Containing); Animals; Female; Kidney; Liver; Ornithine Decarboxylase; Polyamines; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Transglutaminases | 1986 |
Correlation of changes in transglutaminase activity and polyamine content of neoplastic tissue during the metastatic process.
Topics: Animals; Cell Division; Kinetics; Neoplasm Metastasis; Putrescine; Rats; Sarcoma, Experimental; Spermidine; Spermine; Transglutaminases | 1987 |
Covalent incorporation of polyamines as gamma-glutamyl derivatives into CHO cell protein.
Topics: Animals; Cell Division; Cell Line; Cricetinae; Cricetulus; Eflornithine; Female; Mitoguazone; Ovary; Polyamines; Proteins; Putrescine; Spermidine; Spermine; Transglutaminases | 1988 |
Retinoic acid-induced modulation of rat liver transglutaminase and total polyamines in vivo.
Topics: Animals; Dactinomycin; Intracellular Fluid; Liver; Male; Polyamines; Proteins; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Transglutaminases; Tretinoin; Vitamin A | 1988 |
1,2-Dimethylhydrazine-induced alterations in N1-acetylspermidine levels and spermidine N1-acetyltransferase activity in rat colonic mucosa.
Topics: 1,2-Dimethylhydrazine; Acetyltransferases; Animals; Colon; Dimethylhydrazines; Intestinal Mucosa; Male; Methylhydrazines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine | 1989 |
Polyamines are sufficient to drive the transport of the precursor of ornithine carbamoyltransferase into rat liver mitochondria: possible effect on mitochondrial membranes.
Topics: Animals; Biological Transport; Enzyme Precursors; Intracellular Membranes; Microscopy, Electron; Mitochondria, Liver; Ornithine Carbamoyltransferase; Protein Processing, Post-Translational; Putrescine; Rats; RNA, Messenger; Spermidine; Spermine | 1989 |
Inhibition of mammalian spermine synthase by N-alkylated-1,3-diaminopropane derivatives in vitro and in cultured rat hepatoma cells.
Topics: Animals; Cattle; Cells, Cultured; Diamines; Liver Neoplasms, Experimental; Putrescine; Rats; Spermidine; Spermidine Synthase; Spermine; Spermine Synthase; Spleen; Transferases | 1989 |
Spermidine/spermine-N1-acetyltransferase activity in isoprenaline-stimulated rat salivary glands.
Topics: Acetyltransferases; Animals; Infusions, Intravenous; Isoproterenol; Male; Organ Size; Ornithine Decarboxylase; Putrescine; Rats; Rats, Inbred Strains; Salivary Glands; Spermidine; Spermine | 1989 |
Receptors involved in the nervous system regulation of polyamine metabolism in rat salivary glands.
Topics: Animals; Atropine; Dihydroergotamine; Male; Ornithine Decarboxylase; Parasympathetic Nervous System; Phentolamine; Propranolol; Putrescine; Rats; Rats, Inbred Strains; Salivary Glands; Spermidine; Spermine; Sympathetic Nervous System; Yohimbine | 1989 |
Effects of beta-endorphin on ornithine decarboxylase in tissues of developing rats: a potential role for this endogenous neuropeptide in the modulation of tissue growth.
Topics: Animals; beta-Endorphin; Brain; Drug Interactions; Endorphins; Female; Kidney; Liver; Male; Naloxone; Ornithine Decarboxylase; Pregnancy; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1986 |
Polyamine transport in Neurospora crassa.
Topics: Biological Transport; Cations; Hydrogen-Ion Concentration; Kinetics; Mitoguazone; Neurospora; Neurospora crassa; Polyamines; Potassium Chloride; Putrescine; Spermidine; Spermine | 1988 |
Growth and hormonal responsiveness of human endometrial stromal cells in culture.
Topics: Age Factors; Cell Differentiation; Cell Division; Cells, Cultured; Culture Media; Cytoskeleton; Endometrium; Estradiol; Female; Humans; Progesterone; Progestins; Putrescine; Spermidine; Spermine | 1988 |
Inhibition of the activity of restriction endonucleases by spermidine and spermine.
Topics: DNA Restriction Enzymes; Escherichia coli; Kinetics; Plasmids; Putrescine; Spermidine; Spermine | 1985 |
The characterization and regulation of a polyamine-responsive, cyclic nucleotide-independent protein kinase activity in the mouse mammary gland.
Topics: Adenosine Triphosphate; Animals; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cyclic AMP; Cyclic GMP; Cytosol; Female; Kinetics; Magnesium; Mammary Glands, Animal; Mice; Mice, Inbred C3H; Molecular Weight; Polyamines; Polylysine; Pregnancy; Protein Kinases; Spermidine; Spermine | 1985 |
Polyamines and nucleic acids in gestational trophoblastic tumors.
Topics: Adult; Choriocarcinoma; DNA, Neoplasm; Female; Humans; Hydatidiform Mole; Middle Aged; Polyamines; Pregnancy; Putrescine; RNA, Neoplasm; Spermidine; Spermine; Trophoblastic Neoplasms; Uterine Neoplasms | 1985 |
Apparently unidirectional polyamine transport by proton motive force in polyamine-deficient Escherichia coli.
Topics: Biological Transport, Active; Calcimycin; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Magnesium; Membrane Potentials; Polyamines; Potassium Chloride; Protons; Putrescine; Spermidine; Spermine | 1986 |
Digestion of the chicken beta-globin gene chromatin with micrococcal nuclease reveals the presence of an altered nucleosomal array characterized by an atypical ladder of DNA fragments.
Topics: Animals; Chickens; Chromatin; DNA; DNA Restriction Enzymes; Erythrocytes; Female; Genes; Globins; Micrococcal Nuclease; Nucleosomes; Oligodeoxyribonucleotides; Oviducts; Reticulocytes; Spermidine; Spermine | 1986 |
A cyclic AMP-independent protein kinase from Candida albicans.
Topics: Candida albicans; Chromatography, Affinity; Cyclic AMP; Heparin; Molecular Weight; Protein Kinase Inhibitors; Protein Kinases; Spermidine; Spermine; Substrate Specificity | 1986 |
Stimulation of polyamine biosynthesis by follicle-stimulating hormone in serum-free cultures of rat Sertoli cells.
Topics: Animals; Bucladesine; Cyclic AMP; Eflornithine; Estradiol; Follicle Stimulating Hormone; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Sertoli Cells; Spermidine; Spermine | 1987 |
A proton magnetic resonance study of the effects of polyamine and divalent metal ions on diadenosine 5',5'''-P1,P4-tetraphosphate base stacking.
Topics: Adenine Nucleotides; Adenosine; Cations, Divalent; Dinucleoside Phosphates; Kinetics; Magnesium; Magnetic Resonance Spectroscopy; Protons; Putrescine; Spermidine; Spermine | 1987 |
Synthesis of cytomegalovirus DNA is an antiviral target late in virus growth.
Topics: Acyclovir; Antiviral Agents; Cell Line; Cytomegalovirus; DNA, Viral; Floxuridine; Foscarnet; Ganciclovir; Humans; Phosphonoacetic Acid; Spermidine; Spermine; Viral Proteins | 1987 |
Polyamine stimulation of protein phosphatase-2A from rat liver using a non-protein phosphoester substrate.
Topics: Animals; Chromatography; Enzyme Activation; Freezing; Hot Temperature; Kinetics; Liver; Male; Nitrophenols; Organophosphorus Compounds; Phosphoprotein Phosphatases; Phosphoproteins; Polyamines; Protein Phosphatase 2; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1986 |
A possible mechanism of protection by polyamines against gastric damage induced by acidified ethanol in rats: polyamine protection may depend on its antiperoxidative properties.
Topics: Administration, Oral; Animals; Ethanol; Gastric Mucosa; Hydrochloric Acid; Iron; Lipid Peroxides; Male; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Sulfhydryl Compounds; Superoxides; Swine; Time Factors | 1987 |
Purification of polyamine oxidase from maize seedlings by immunoadsorbent column.
Topics: Edible Grain; Electrophoresis, Polyacrylamide Gel; Hordeum; Hydrogen-Ion Concentration; Immunosorbent Techniques; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Precipitin Tests; Sodium Dodecyl Sulfate; Spermidine; Spermine; Zea mays | 1988 |
Relationship between ornithine decarboxylase activity and hexamethylene bisacetamide-induced differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Clone Cells; Dexamethasone; Eflornithine; Erythrocytes; Interphase; Kinetics; Leukemia, Erythroblastic, Acute; Mice; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine | 1986 |
Restoration of the polyamine contents in rat hepatoma tissue-culture cells after inhibition of polyamine biosynthesis. Relationship with cell proliferation.
Topics: Alkynes; Animals; Cell Division; Cells, Cultured; Diamines; Eflornithine; Liver Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1986 |
In vivo effects of DL-alpha-difluoromethylornithine on the polyamine and nucleotide phosphate metabolism in P388/S leukemia cells.
Topics: Animals; Cell Line; Eflornithine; Leukemia P388; Leukemia, Experimental; Male; Mice; Mice, Inbred Strains; Nucleotides; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine; Time Factors | 1986 |
Polyamines in 1 alpha, 25-dihydroxycholecalciferol-induced differentiation of human promyelocytic leukemia cells, HL-60.
Topics: Acetyltransferases; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Eflornithine; Humans; Leukemia, Myeloid; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1986 |
Polyamines and growth regulation of cultured human breast cancer cells by 17 beta-oestradiol.
Topics: Breast Neoplasms; Cell Division; Cell Line; Eflornithine; Estradiol; Humans; Insulin; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine; Tamoxifen | 1986 |
Regional pattern and heat-resistance of brain 5'-deoxy-5'-methylthioadenosine phosphorylase.
Topics: Animals; Brain; Cattle; Hot Temperature; Mice; Pentosyltransferases; Protein Denaturation; Purine-Nucleoside Phosphorylase; Rats; Rats, Inbred Strains; Sheep; Species Specificity; Spermidine; Spermine; Swine; Tissue Distribution | 1986 |
Polyamine biosynthesis in trichomonads.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Culture Media; Eflornithine; Eukaryota; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Trichomonas vaginalis; Tritrichomonas | 1986 |
Putrescine does not mediate the androgen-response in mouse kidney.
Topics: Animals; Eflornithine; Female; Kidney; Mice; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; RNA, Messenger; Spermidine; Spermine; Testosterone | 1986 |
Inhibition of the respiratory burst of human neutrophils by the polyamine oxidase-polyamine system.
Topics: Animals; Carbon Dioxide; Catalase; Cattle; Female; Hexosephosphates; Humans; Kinetics; Male; Neutrophils; Oxidoreductases Acting on CH-NH Group Donors; Oxygen Consumption; Polyamine Oxidase; Pregnancy; Spermidine; Spermine | 1986 |
Erythrocyte polyamine levels during intravenous feeding of patients with colorectal carcinoma.
Topics: Colonic Neoplasms; Erythrocytes; Humans; Parenteral Nutrition; Polyamines; Prealbumin; Putrescine; Rectal Neoplasms; Retinol-Binding Proteins; Retinol-Binding Proteins, Plasma; Spermidine; Spermine | 1986 |
Effects of DL-alpha-difluoromethylornithine on Leishmania donovani promastigotes.
Topics: Animals; Eflornithine; Leishmania donovani; Putrescine; Spermidine; Spermine | 1986 |
Relationship between heat sensitivity and polyamine levels after treatment with alpha-difluoromethylornithine (DFMO).
Topics: Cell Division; Cells, Cultured; Eflornithine; Hot Temperature; Polyamines; Putrescine; Spermidine; Spermine | 1986 |
Polyamines and HeLa-cell DNA replication.
Topics: DNA Replication; Eflornithine; HeLa Cells; Humans; Interphase; Polyamines; Putrescine; Spermidine; Spermine; Thymidine | 1986 |
Sensitization of Chinese hamster ovary cells to heat shock by alpha-difluoromethylornithine.
Topics: Animals; Cell Line; Cell Survival; Colony-Forming Units Assay; Cricetinae; Cricetulus; Eflornithine; Female; Hot Temperature; Kinetics; Ovary; Putrescine; Spermidine; Spermine | 1987 |
Post-translational modification of the protein-synthesis initiation factor eIF-4D by spermidine in rat hepatoma cells.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Liver Neoplasms, Experimental; Lysine; Neoplasm Proteins; Peptide Initiation Factors; Protein Binding; Protein Biosynthesis; Rats; RNA-Binding Proteins; Spermidine; Spermine | 1986 |
Transient elevation of intrasynaptosomal free calcium by putrescine.
Topics: Animals; Brain; Calcium; Eflornithine; In Vitro Techniques; Male; Potassium; Putrescine; Rats; Spermidine; Spermine; Synaptosomes | 1987 |
Synergistic inhibition of polyamine synthesis and growth by difluoromethylornithine plus methylthioadenosine in methylthioadenosine phosphorylase-deficient murine lymphoma cells.
Topics: Adenosine; Animals; Cell Division; Cell Line; Deoxyadenosines; Drug Synergism; Eflornithine; Kinetics; Lymphoma; Mice; Pentosyltransferases; Polyamines; Purine-Nucleoside Phosphorylase; Putrescine; Spermidine; Spermine; Thionucleosides | 1987 |
Multiple pathways for uptake of paraquat, methylglyoxal bis(guanylhydrazone), and polyamines.
Topics: Aminoisobutyric Acids; Animals; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Eflornithine; Female; Mitoguazone; Ovary; Paraquat; Polyamines; Putrescine; Spermidine; Spermine | 1987 |
The formation and stability of the hypusine containing protein in Chinese hamster ovary cells.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; Eukaryotic Translation Initiation Factor 5A; Female; Lysine; Molecular Weight; Ovary; Peptide Initiation Factors; Putrescine; RNA-Binding Proteins; Spermidine; Spermine | 1987 |
[Polyamine levels and diamine oxidase activity in the rat liver and kidneys during hepatocarcinogenesis induced by N-nitrosodiethylamine].
Topics: Amine Oxidase (Copper-Containing); Animals; Diethylamines; Diethylnitrosamine; Kidney; Liver; Liver Neoplasms, Experimental; Male; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1987 |
Permissive role for ornithine decarboxylase and putrescine in the luteinising hormone surge.
Topics: Animals; Eflornithine; Female; Gonadotropin-Releasing Hormone; In Vitro Techniques; Kinetics; Luteinizing Hormone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pituitary Gland, Anterior; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1987 |
Enhanced antitumor efficacy with a combination of hyperthermochemotherapy and thermosensitization with polyamine antimetabolites in nude mice.
Topics: Animals; Antimetabolites, Antineoplastic; DNA, Neoplasm; Eflornithine; Hyperthermia, Induced; Mice; Mice, Inbred BALB C; Mice, Nude; Mitoguazone; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Polyamines; Putrescine; Spermidine; Spermine; Stomach Neoplasms; Time Factors | 1987 |
Influence of avian aflatoxicosis on the synthesis of polyamines.
Topics: Aflatoxins; Animals; Arginase; Arginine; Brain; Chickens; Kidney; Liver; Lysine; Male; Ornithine Decarboxylase; Polyamines; Poultry Diseases; Putrescine; Spermidine; Spermine; Threonine | 1987 |
Analysis of polyamines as their dabsyl derivatives by reversed-phase high-performance liquid chromatography.
Topics: Cadaverine; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; p-Dimethylaminoazobenzene; Polyamines; Putrescine; Salmonella typhimurium; Spermidine; Spermine | 1987 |
Polyamines mediate uncontrolled calcium entry and cell damage in rat heart in the calcium paradox.
Topics: Animals; Calcium; Cytosol; Eflornithine; Female; Heart Diseases; Hypothermia, Induced; Microscopy, Electron; Myocardial Contraction; Myocardium; Myoglobin; Ornithine Decarboxylase; Perfusion; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1987 |
Effect of dietary lysine on polyamine synthesis in the chick.
Topics: Adenosylmethionine Decarboxylase; Amino Acids; Animals; Arginase; Arginine; Chickens; Diet; Kidney; Liver; Lysine; Nutritional Requirements; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1987 |
Role of polyamines in intestinal adaptation in the rat.
Topics: Amine Oxidase (Copper-Containing); Animals; Biliary Tract; Cadaverine; Hyperplasia; Intestinal Mucosa; Male; Organ Size; Pancreas; Parenteral Nutrition, Total; Polyamines; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1987 |
Chain-fluorinated polyamines as tumor markers--I. In vivo transformation of 2,2-difluoroputrescine into 6,6-difluorospermidine and 6,6-difluorospermine.
Topics: Animals; Biomarkers, Tumor; Biotransformation; Cattle; Cell Division; Eflornithine; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Polyamines; Putrescine; Rats; Rats, Inbred BUF; Spermidine; Spermine | 1987 |
Mucosal polyamine profile in normal and adapting (hypo and hyperplastic) intestine: effects of DFMO treatment.
Topics: Adaptation, Physiological; Animals; Eflornithine; Hyperplasia; Intestinal Mucosa; Intestine, Small; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1987 |
Effect of polyamine depletion on c-myc expression in human colon carcinoma cells.
Topics: Actins; Cell Cycle; Cell Division; Colonic Neoplasms; Dactinomycin; Eflornithine; Gene Expression Regulation; Half-Life; Histones; Humans; Ornithine Decarboxylase; Polyamines; Proto-Oncogenes; RNA, Messenger; Spermidine; Spermine; Tumor Cells, Cultured | 1988 |
Ornithine decarboxylase and polyamine levels in columnar upper gastrointestinal mucosae in patients with Barrett's esophagus.
Topics: Barrett Esophagus; Cell Division; Eflornithine; Epithelial Cells; Epithelium; Esophageal Diseases; Gastric Mucosa; Humans; Intestinal Mucosa; Intestine, Small; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1988 |
Treatment with polyamine synthesis inhibitors reduces the positive inotropic effect of ouabain, noradrenaline and calcium.
Topics: Animals; Calcium; Cardiotonic Agents; Eflornithine; Heart; Norepinephrine; Ouabain; Polyamines; Putrescine; Pyruvaldehyde; Rats; Spermidine; Spermine | 1988 |
Polyamines, ornithine decarboxylase, and diamine oxidase in the substantia nigra and striatum of the male rat after hemitransection.
Topics: Amine Oxidase (Copper-Containing); Animals; Cadaverine; Corpus Striatum; Diencephalon; Kinetics; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Substantia Nigra | 1988 |
Failure of ornithine decarboxylase inhibition to alter small intestinal epithelial repair after transient segmental ischaemia.
Topics: Animals; Eflornithine; Intestinal Mucosa; Intestine, Small; Ischemia; Ornithine Decarboxylase Inhibitors; Polyamines; Rabbits; Spermidine; Spermine | 1988 |
Renal ornithine decarboxylase activity, polyamines, and compensatory renal hypertrophy in the rat.
Topics: Animals; Eflornithine; Hypertrophy; Kidney; Kinetics; Male; Nephrectomy; Ornithine Decarboxylase; Putrescine; Rats; Rats, Inbred Strains; Reference Values; Spermidine; Spermine | 1988 |
Polyamine depletion and growth inhibition in Candida albicans and Candida tropicalis by alpha-difluoromethylornithine and cyclohexylamine.
Topics: Candida; Candida albicans; Cyclohexylamines; Dose-Response Relationship, Drug; Eflornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1988 |
Role of polyamines in the stimulation of synthesis and secretion of plasminogen activator from bovine aortic endothelial cells.
Topics: Animals; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Eflornithine; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Glycoproteins; Mitoguazone; Plasminogen Activators; Plasminogen Inactivators; Polyamines; Putrescine; Spermidine; Spermine | 1988 |
Polyamines are involved in the 1-alpha,25-dihydroxyvitamin D3-induced fusion of mouse alveolar macrophages.
Topics: Animals; Calcitriol; Cell Fusion; Cells, Cultured; Eflornithine; Macrophages; Male; Mice; Mitoguazone; Polyamines; Protein Biosynthesis; Pulmonary Alveoli; Spermidine; Spermine | 1986 |
Studies of non-metabolizable polyamines that support growth of SV-3T3 cells depleted of natural polyamines by exposure to alpha-difluoromethylornithine.
Topics: Acetyltransferases; Animals; Cell Division; Cell Line; Eflornithine; Rats; Spermidine; Spermine; Spermine Synthase; Substrate Specificity | 1988 |
Effect of DL-alpha-difluoromethylornithine on polyamine synthesis and interconversion in Trichomonas vaginalis grown in a semi-defined medium.
Topics: Adenosine; Animals; Cadaverine; Chromatography, High Pressure Liquid; Culture Media; Eflornithine; Ornithine Decarboxylase; Polarography; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Trichomonas vaginalis | 1988 |
Polyamine content in pulmonary arteries from rats with monocrotaline-induced pulmonary hypertension.
Topics: Animals; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Polyamines; Pulmonary Artery; Putrescine; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Spermidine; Spermine | 1988 |
Effect of inhibitors of S-adenosylmethionine decarboxylase on the contents of ornithine decarboxylase and S-adenosylmethionine decarboxylase in L1210 cells.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Deoxyadenosines; Leukemia L1210; Ornithine Decarboxylase; Polyamines; Proteins; RNA, Messenger; Spermidine; Spermine; Tumor Cells, Cultured | 1988 |
The effects of chronic ethanol administration on polyamine content during dimethylhydrazine-induced colorectal carcinogenesis in the rat.
Topics: Animals; Colon; Colorectal Neoplasms; Dimethylhydrazines; Ethanol; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Rectum; Spermidine; Spermine | 1988 |
Purification by affinity chromatography and characterization of porcine liver cytoplasmic polyamine oxidase.
Topics: Animals; Catalysis; Chromatography, Affinity; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Isoelectric Focusing; Liver; Molecular Weight; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Spermine; Subcellular Fractions; Substrate Specificity; Swine | 1988 |
The superstructure of chromatin and its condensation mechanism. V. Effect of linker length, condensation by multivalent cations, solubility and electric dichroism properties.
Topics: Animals; Cations, Divalent; Cations, Monovalent; Chickens; Chromatin; Erythrocytes; Hydrogen Bonding; Male; Nucleosomes; Particle Accelerators; Scattering, Radiation; Sea Urchins; Solubility; Spermatozoa; Spermidine; Spermine; X-Rays | 1988 |
Spermine, another specific allosteric activator of calcium uptake in rat liver mitochondria.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Female; Kinetics; Magnesium; Mitochondria, Heart; Mitochondria, Liver; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1988 |
Feedback regulation of polyamine synthesis in Ehrlich ascites tumor cells. Analysis using nonmetabolizable derivatives of putrescine and spermine.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Feedback; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Protein Biosynthesis; Putrescine; RNA, Messenger; Spermidine; Spermine | 1988 |
Inhibition of bovine serum amine oxidase activity by aminoalkylaminoanthraquinones.
Topics: Amine Oxidase (Copper-Containing); Animals; Anthraquinones; Cattle; Kinetics; Oxidoreductases Acting on CH-NH Group Donors; Spermidine; Spermine; Structure-Activity Relationship | 1988 |
[Changes in the content of bound polyamines in the whole blood in patients with chronic leukemia].
Topics: Biogenic Polyamines; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Spermidine; Spermine | 1988 |
Calmodulin antagonist trifluoperazine inhibits polyamine biosynthesis and liver regeneration.
Topics: Animals; Calmodulin; Hepatectomy; Liver; Liver Regeneration; Male; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Time Factors; Trifluoperazine | 1988 |
[Fractional composition of free polyamines in the bone marrow and peripheral blood leukocytes in healthy persons and in patients with chronic leukemia].
Topics: Bone Marrow; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocytes; Putrescine; Reference Values; Spermidine; Spermine | 1988 |
The importance of polyamine determination in monitoring malignant gynaecological tumours.
Topics: Antigens, Tumor-Associated, Carbohydrate; Biomarkers, Tumor; Carcinoembryonic Antigen; Female; Humans; Lipids; N-Acetylneuraminic Acid; Ovarian Neoplasms; Polyamines; Putrescine; Sialic Acids; Spermidine; Spermine | 1988 |
gamma-Glutamylamine derivatives in isolated rat hepatocyte proteins.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dipeptides; Hydrolysis; Liver; Polyamines; Proteins; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1988 |
Polyamines and cell proliferation in the sea star Pycnopodia helianthoides.
Topics: Animals; Cadaverine; Cell Division; DNA; Echinodermata; Polyamines; Proteins; Putrescine; Spermidine; Spermine; Tissue Distribution | 1988 |
Chain-fluorinated polyamines as tumor markers--IV. Comparison of 2-fluoroputrescine and 2,2-difluoroputrescine as substrates of spermidine synthase in vitro and in vivo.
Topics: Animals; Binding Sites; Biomarkers, Tumor; Dose-Response Relationship, Drug; In Vitro Techniques; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Mice, Inbred C57BL; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1988 |
Regulation of mammalian S-adenosylmethionine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Chemical Phenomena; Chemistry; Cloning, Molecular; DNA Probes; Electrophoresis, Polyacrylamide Gel; Growth Substances; Rats; Reticulocytes; RNA, Messenger; Spermidine; Spermine | 1988 |
Polyamine lowered the hepatic lipid peroxide level in rats.
Topics: Animals; Carbon Tetrachloride; Lipid Peroxides; Liver; Male; NADH Dehydrogenase; Organ Size; Oxidation-Reduction; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Spermidine; Spermine | 1988 |
[Studies on polyamine of gingival tissues in marginal periodontitis].
Topics: Adult; Female; Gingiva; Humans; Male; Periodontitis; Polyamines; Putrescine; Spermidine; Spermine | 1988 |
Polyamines stimulate the "in vitro" transport of the precursor of ornithine carbamoyltransferase into rat liver mitochondria.
Topics: Animals; Biological Transport; Enzyme Precursors; In Vitro Techniques; Mitochondria, Liver; Ornithine Carbamoyltransferase; Polyamines; Rats; Reticulocytes; Spermidine; Spermine | 1988 |
Uptake of polyamines by human lymphocytes and their effect on lactate formation from glucose.
Topics: Glucose; Humans; In Vitro Techniques; Lactates; Lymphocytes; Ouabain; Polyamines; Putrescine; Spermidine; Spermine | 1988 |
Chain-fluorinated polyamines as tumour markers. III. Determination of geminal difluoropolyamines and their precursor 2,2-difluoroputrescine in normal tissues and experimental tumours by in vitro and in vivo 19F NMR spectroscopy.
Topics: Animals; Biomarkers, Tumor; Liver; Magnetic Resonance Spectroscopy; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Putrescine; Spermidine; Spermine | 1988 |
Polyamines inhibit the yeast histone deacetylase.
Topics: Acetates; Amidohydrolases; Histone Deacetylase Inhibitors; Polyamines; Saccharomyces cerevisiae; Spermidine; Spermine | 1987 |
Endogenous polyamines are intimately associated with highly condensed chromatin in vivo. A fluorescence cytochemical and immunocytochemical study of spermine and spermidine during the cell cycle and in reactivated nuclei.
Topics: Animals; Cell Cycle; Cell Nucleus; Chickens; Chromatin; Erythrocytes; HeLa Cells; Humans; Immunoenzyme Techniques; Spermidine; Spermine | 1987 |
The polyamines putrescine, spermidine and spermine in human gingival crevicular fluid.
Topics: Gingival Crevicular Fluid; Gingivitis; Homeostasis; Humans; Periodontitis; Putrescine; Spermidine; Spermine | 1987 |
Polyamine content as a marker of radiation injury in the rat spleen.
Topics: Animals; Cobalt Radioisotopes; Female; Gamma Rays; Polyamines; Putrescine; Radiation Injuries, Experimental; Rats; Rats, Inbred Strains; Spermidine; Spermine; Spleen; Whole-Body Irradiation | 1987 |
Modulation of polyamine-biosynthetic activity by S-adenosylmethionine depletion.
Topics: Aminobutyrates; Animals; Cycloheximide; Methionine Adenosyltransferase; Mice; Ornithine Decarboxylase; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Tumor Cells, Cultured | 1988 |
Free and protein-conjugated polyamines in mouse epidermal cells. Effect of high calcium and retinoic acid.
Topics: Animals; Calcium; Cells, Cultured; Guanidines; Kinetics; Mice; Mice, Inbred BALB C; Polyamines; Protein Binding; Proteins; Putrescine; Skin; Spermidine; Spermine; Tretinoin | 1988 |
[Significance of polyamines for the early diagnosis of spontaneous hemoblastoses in AKR mice].
Topics: Animals; Biomarkers, Tumor; Brain Chemistry; Female; Kidney; Liver; Lung; Lymphoma; Male; Mice; Mice, Inbred AKR; Polyamines; Putrescine; Spermidine; Spermine; Spleen; Thymus Gland | 1988 |
A screening method for the simultaneous determination of putrescine, cadaverine, histamine, spermidine and spermine in fish by means of high pressure liquid chromatography of their 5-dimethylaminonaphthalene-1-sulphonyl derivatives.
Topics: Animals; Cadaverine; Chromatography, High Pressure Liquid; Dansyl Compounds; Diamines; Fishes; Histamine; Indicators and Reagents; Meat; Putrescine; Spermidine; Spermine | 1988 |
Endogenous polyamines associate with DNA during its condensation in mammalian tissue. A fluorescence cytochemical and immunocytochemical study of polyamines in fetal rat liver.
Topics: Animals; DNA; Erythroblasts; Erythropoiesis; Female; Liver; Mitosis; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1988 |
Clinical significance of serum spermine in breast cancer.
Topics: Adult; Breast Diseases; Breast Neoplasms; Carcinoembryonic Antigen; Female; Glucose-6-Phosphate Isomerase; Humans; Middle Aged; Neoplasm Recurrence, Local; Putrescine; Spermidine; Spermine | 1988 |
Spermine and spermidine induce intestinal maturation in the rat.
Topics: Age Factors; Animals; Disaccharidases; DNA; Dose-Response Relationship, Drug; Intestinal Mucosa; Intestines; Proteins; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1988 |
Polyamines and the catalytic domain of protein kinase C.
Topics: Animals; Brain; Cadaverine; Calcium; Chromatography, Gel; Histones; Peptide Fragments; Phospholipids; Phosphorylation; Polyamines; Protein Kinase C; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Structure-Activity Relationship | 1988 |
The effect of structural changes in a polyamine backbone on its DNA-binding properties.
Topics: Animals; Binding, Competitive; Cattle; Diminazene; DNA; Ethidium; Hydrogen Bonding; Putrescine; Spectrometry, Fluorescence; Spermidine; Spermine | 1988 |
The accumulation and localisation of putrescine, spermidine, spermine and paraquat in the rat lung. In vitro and in vivo studies.
Topics: Animals; Autoradiography; Biological Transport; Carbon Radioisotopes; Lung; Male; Paraquat; Perfusion; Putrescine; Rats; Spermidine; Spermine; Tissue Distribution; Tritium | 1988 |
A twenty-two-fold increase in the relative affinity of estrogen receptor to poly (dA-dC).poly (dG-dT) in the presence of polyamines.
Topics: Animals; Binding, Competitive; Chromatography, Affinity; Cytosol; DNA; Female; Kinetics; Polydeoxyribonucleotides; Putrescine; Rabbits; Receptors, Estrogen; Spermidine; Spermine; Uterus | 1988 |
Polyamine distribution among maize embryonic tissues and its relation to seed germination.
Topics: Polyamines; Putrescine; Seeds; Spermidine; Spermine; Zea mays | 1988 |
Relationships between polyamine, deoxyribonucleic acid and oestrogen receptor binding site concentrations in human breast tumours.
Topics: Breast Neoplasms; DNA, Neoplasm; Female; Humans; Polyamines; Putrescine; Receptors, Estrogen; Spermidine; Spermine | 1988 |
Prolonged, intravenous paraquat infusion in the rat. II. Paraquat-induced alterations in lung polyamine metabolism.
Topics: Animals; Lung; Male; Ornithine Decarboxylase; Paraquat; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1988 |
Polyamine levels and gastrin receptors in colon cancers.
Topics: Carcinoma; Colonic Neoplasms; Humans; Intestinal Mucosa; Neoplasm Staging; Polyamines; Putrescine; Receptors, Cholecystokinin; Spermidine; Spermine | 1988 |
Passive sequestration of putrescine, spermidine and spermine by rat lungs.
Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Harmaline; In Vitro Techniques; Lung; Male; Ouabain; Perfusion; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1988 |
Effects of food restriction and hyperoxia on rat survival and lung polyamine metabolism.
Topics: Animals; Food Deprivation; Lung; Male; Oxygen; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1988 |
Effect of dietary zinc deficiency and the associated drop in voluntary food intake on rat erythrocyte membrane polyamines.
Topics: Analysis of Variance; Animals; Cytosol; Eating; Erythrocyte Membrane; Evaluation Studies as Topic; Male; Methods; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Time Factors; Zinc | 1988 |
Quantitation of polyamines using thin-layer chromatography and image analysis.
Topics: Chromatography, Thin Layer; Plants; Polyamines; Putrescine; Spectrophotometry, Ultraviolet; Spermidine; Spermine | 1988 |
Characterization of the inducible polyamine transporter in bovine lymphocytes.
Topics: Animals; Cattle; Cells, Cultured; Concanavalin A; DNA; Lymphocytes; Membrane Potentials; Polyamines; Putrescine; Spermidine; Spermine | 1988 |
Acetylation of spermidine and methylglyoxal bis(guanylhydrazone) in baby-hamster kidney cells (BHK-21/C13).
Topics: Acetylation; Acetyltransferases; Animals; Cell Nucleus; Cells, Cultured; Chromatography, High Pressure Liquid; Cricetinae; Cytosol; Half-Life; Kidney; Mitoguazone; Putrescine; Spermidine; Spermine | 1988 |
Polyamine distribution and activity of their biosynthetic enzymes in the European sea bass (Dicentrarchus labrax L.) compared to the rat.
Topics: Adenosylmethionine Decarboxylase; Animals; Bass; Enzyme Stability; Liver; Male; Ornithine Decarboxylase; Perciformes; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1987 |
Putrescine derivatives as substrates of spermidine synthase.
Topics: Animals; Cattle; Chickens; Mass Spectrometry; Putrescine; Spermidine; Spermidine Synthase; Spermine; Substrate Specificity; Transferases | 1987 |
Changes of polyamine concentrations in infants during the first six months of life.
Topics: Aging; Diet; Female; Humans; Infant; Infant, Newborn; Male; Polyamines; Spermidine; Spermine | 1987 |
Amines in fresh beef of normal pH and the role of bacteria in changes in concentration observed during storage in vacuum packs at chill temperatures.
Topics: Amines; Animals; Bacteria; Cadaverine; Cattle; Chromatography, High Pressure Liquid; Food Microbiology; Food Preservation; Histamine; Lactobacillus; Meat; Putrescine; Spermidine; Spermine; Temperature; Vacuum | 1987 |
Evolution of red blood cell polyamine levels in partially hepatectomized rat.
Topics: Animals; DNA; Erythrocytes; Hepatectomy; Liver; Liver Regeneration; Male; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Time Factors | 1987 |
Regional profile of polyamines in reversible cerebral ischemia of Mongolian gerbils.
Topics: Animals; Cerebral Cortex; Corpus Striatum; Female; Guinea Pigs; Hippocampus; Ischemic Attack, Transient; Polyamines; Putrescine; Spermidine; Spermine; Thalamus; Time Factors | 1987 |
Developmental aspects of polyamine interconversion in rat brain.
Topics: Aging; Animals; Blood-Brain Barrier; Brain; Female; Male; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Rats; Rats, Inbred BUF; Rats, Inbred Strains; Spermidine; Spermine | 1986 |
Effects of ornithine decarboxylase inhibition on c-myc expression during murine erythroleukemia cell proliferation and differentiation.
Topics: Acetamides; Animals; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Gene Expression Regulation; Leukemia, Erythroblastic, Acute; Mice; Oncogenes; Ornithine Decarboxylase Inhibitors; Phenotype; Putrescine; RNA, Neoplasm; Spermidine; Spermine; Transcription, Genetic | 1986 |
Polyamine regulation of protein phosphorylation in the brain of the tobacco hornworm, Manduca sexta.
Topics: Animals; Brain; Casein Kinases; Chemical Phenomena; Chemistry, Physical; Cytosol; Lepidoptera; Molecular Weight; Nerve Tissue Proteins; Phosphoproteins; Phosphorylation; Polyamines; Potassium Chloride; Protein Kinases; Pupa; Putrescine; Spermidine; Spermine | 1987 |
Inhibition of growth but not differentiation of normal and leukemic myeloid cells by methylthioadenosine.
Topics: Adenosine; Cell Differentiation; Cell Division; Cell Line; Colony-Forming Units Assay; Deoxyadenosines; Granulocytes; Humans; Leukemia, Myeloid, Acute; Macrophages; Spermidine; Spermine; Tetradecanoylphorbol Acetate; Thionucleosides | 1987 |
[Polyamine level as a possible criterion for the evaluation of resistance to chemotherapy of children with acute leukemia].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Drug Resistance; Electrophoresis; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Polyamines; Prognosis; Putrescine; Spermidine; Spermine | 1987 |
Characterization of a casein kinase which interacts with the rabbit progesterone receptor. Differences with the in vivo hormone-dependent phosphorylation.
Topics: Animals; Casein Kinases; Cell Nucleus; Cytosol; Female; Heparin; Kinetics; Molecular Weight; Osmolar Concentration; Phosphorylation; Protein Kinases; Rabbits; Receptors, Progesterone; Spermidine; Spermine; Substrate Specificity; Uterus | 1987 |
Influence of the polyamines spermine and spermidine on yeast tRNAPhe as revealed from its imino proton NMR spectrum.
Topics: Base Composition; Dimethyl Sulfoxide; Kinetics; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae; Solvents; Spermidine; Spermine | 1986 |
Effects of polyamines on proline endopeptidase activity in rat brain.
Topics: Animals; Brain; Cytosol; Endopeptidases; Female; Magnesium; Polyamines; Prolyl Oligopeptidases; Putrescine; Rats; Rats, Inbred Strains; Serine Endopeptidases; Spermidine; Spermine | 1986 |
Polyamine cytochemistry: comparisons between cytochemical, autoradiographic, immunocytochemical and chemical results in the prostate.
Topics: Animals; Autoradiography; Fluorescamine; Histocytochemistry; Immunologic Techniques; Male; o-Phthalaldehyde; Prostate; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1986 |
Glutathione localization by a novel o-phthalaldehyde histofluorescence method.
Topics: Aldehydes; Animals; Bromobenzenes; Fluorescent Antibody Technique; Glutathione; Histocytochemistry; Liver; Male; Maleates; Mice; o-Phthalaldehyde; Spectrometry, Fluorescence; Spermidine; Spermine | 1986 |
Localization and biosynthesis of polyamines in insulin-producing cells.
Topics: Animals; Cells, Cultured; Glucose; Immunoenzyme Techniques; Insulin; Islets of Langerhans; Mice; Ornithine; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1986 |
Polyamine-enhanced casein kinase II in mouse pancreatic islets.
Topics: Animals; Cadaverine; Casein Kinases; Histones; In Vitro Techniques; Islets of Langerhans; Male; Mice; Phosphorylation; Polyamines; Polylysine; Protein Kinase Inhibitors; Protein Kinases; Putrescine; Spermidine; Spermine; Trifluoperazine | 1986 |
Ejaculate composition after masturbation and coitus in the human male.
Topics: Acid Phosphatase; Adult; alpha-Glucosidases; Citrates; Citric Acid; Coitus; Fructose; Humans; Male; Masturbation; Prostaglandins E; Prostate; Proteins; Putrescine; Semen; Sperm Count; Spermidine; Spermine; Testosterone | 1986 |
Spermine and spermidine are non-specific inhibitors of in vitro hematopoiesis.
Topics: Animals; Bone Marrow; Cells, Cultured; Colony-Forming Units Assay; Hematopoiesis; Hematopoietic Stem Cells; Humans; Male; Mice; Mice, Inbred C57BL; Spermidine; Spermine | 1987 |
A simple enzymatic differential assay for diamines, spermidine, and spermine in urine and blood.
Topics: Chromatography, High Pressure Liquid; Diamines; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spectrophotometry; Spermidine; Spermine; Substrate Specificity | 1987 |
Relative abilities of bis(ethyl) derivatives of putrescine, spermidine, and spermine to regulate polyamine biosynthesis and inhibit L1210 leukemia cell growth.
Topics: Adenosylmethionine Decarboxylase; Animals; Biological Transport; Cell Division; Leukemia L1210; Mice; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine; Structure-Activity Relationship | 1987 |
Polyamine changes in reversible cerebral ischemia.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Hippocampus; Polyamines; Putamen; Putrescine; Rats; Spermidine; Spermine | 1987 |
Influence of vitamin E on polyamine metabolism in ozone-exposed rat lungs.
Topics: Animals; Body Weight; Lung; Organ Size; Ozone; Polyamines; Putrescine; Rats; Spermidine; Spermine; Vitamin E; Vitamin E Deficiency | 1987 |
Oxidized polyamines and the growth of human vascular endothelial cells. Prevention of cytotoxic effects by selective acetylation.
Topics: Acetylation; Amine Oxidase (Copper-Containing); Amino Acids; Cell Survival; Cells, Cultured; Endothelium; Humans; Leucine; Macromolecular Substances; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Spermidine; Spermine; Umbilical Veins | 1987 |
Developmental pattern of ornithine decarboxylase activity, S-adenosylmethionine decarboxylase, and polyamines of rat adrenal glands.
Topics: Adenosylmethionine Decarboxylase; Adrenal Glands; Aging; Animals; Carboxy-Lyases; Cold Temperature; Female; Male; Maternal Deprivation; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Restraint, Physical; Spermidine; Spermine; Stress, Physiological | 1987 |
Accumulation of polyamines and their weak association with lower body temperature in elderly convalescent patients.
Topics: Adult; Aged; Aged, 80 and over; Aging; Body Temperature Regulation; Chromatography, High Pressure Liquid; Convalescence; Humans; Hypothermia; Middle Aged; Spermidine; Spermine | 1987 |
[Effect of trans-4-hydroxy-3-methoxycinnamic acid (ferulic acid) on polyamine level in the rat ventral prostate].
Topics: Animals; Cinnamates; Coumaric Acids; Male; Organ Size; Ornithine Decarboxylase Inhibitors; Polyamines; Prostate; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1987 |
Ornithine decarboxylase activity and polyamine content in normal renal tissue and in renal carcinoma.
Topics: Adult; Aged; Carcinoma, Renal Cell; Female; Humans; Kidney; Kidney Cortex; Kidney Medulla; Kidney Neoplasms; Male; Middle Aged; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1987 |
Effects of dexamethasone on spermidine N1-acetyltransferase and ornithine activities in rat spleen.
Topics: Acetyltransferases; Animals; Cytosol; Dexamethasone; Enzyme Induction; Female; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Spleen; Thymus Gland; Tissue Distribution | 1987 |
Selenium and polyamine metabolism: different effect of selenite on liver and bursa of Fabricius ornithine decarboxylase activity.
Topics: Adenosylmethionine Decarboxylase; Animals; Bursa of Fabricius; Chickens; Glutathione; Kinetics; Liver; Male; Ornithine Decarboxylase; Putrescine; Rats; Selenious Acid; Selenium; Spermidine; Spermine | 1987 |
Thermal denaturation of mononucleosomes in the presence of spermine, spermidine, N1-acetylspermidine, N8-acetylspermidine or putrescine: implications for chromosome structure.
Topics: Acetylation; Animals; DNA; Hot Temperature; Nucleic Acid Denaturation; Nucleosomes; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1987 |
Polyamine metabolism in filarial worms.
Topics: Animals; Brugia; Chromatography, High Pressure Liquid; Dirofilaria immitis; Female; Filarioidea; Humans; Male; Onchocerca; Polyamines; Putrescine; Spermidine; Spermine | 1987 |
Polyamine metabolism in Acanthamoeba: polyamine content and synthesis of ornithine, putrescine, and diaminopropane.
Topics: Acanthamoeba; Animals; Arginase; Arginine; Citrulline; Diamines; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Urease | 1987 |
Polyamine metabolism in carcinoma of the oral cavity compared with adjacent and normal oral mucosa.
Topics: Carcinoma, Squamous Cell; Female; Humans; Male; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1987 |
Polyamine metabolism in rat parotid gland after duct ligation.
Topics: Animals; Ligation; Male; Organ Size; Ornithine Decarboxylase; Parotid Gland; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1987 |
Ornithine decarboxylase induction and polyamine biosynthesis by phorone (diisopropylidene acetone), a glutathione depletor, in rats.
Topics: Animals; Enzyme Induction; Glutathione; Ketones; Kinetics; Liver; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Solvents; Spermidine; Spermine | 1987 |
Determination of polyamines in digestive and reproductive tissues of adult Asterias vulgaris (Echinodermata: Asteroidea).
Topics: Animals; Digestive System; Female; Male; Organ Specificity; Ovary; Polyamines; Putrescine; Species Specificity; Spermidine; Spermine; Starfish; Testis | 1987 |
Polyamines stimulate lysosomal cystine transport.
Topics: Animals; Cadaverine; Cells, Cultured; Cystine; Hydrogen-Ion Concentration; Lysosomes; Membrane Potentials; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1987 |
Spermidine and spermine stimulate the transport of the precursor of ornithine carbamoyltransferase into rat liver mitochondria.
Topics: Animals; Biological Transport; Dose-Response Relationship, Drug; Magnesium; Mitochondria, Liver; Ornithine Carbamoyltransferase; Protein Precursors; Rats; Spermidine; Spermine | 1987 |
Modification of the cardiac transmembrane potentials and currents by polyamines.
Topics: Animals; Cats; Female; Guinea Pigs; Heart; Heart Atria; Heart Ventricles; In Vitro Techniques; Male; Membrane Potentials; Spermidine; Spermine | 1987 |
Polyamine changes during senescence and tumorogenesis in plants.
Topics: Adenine; Chlorophyll; Deoxyribonucleases; Hordeum; Kinetin; Plant Development; Plant Tumors; Plants; Polyamines; Putrescine; Ribonucleases; Spermidine; Spermine; Time Factors | 1987 |
Polyamine distribution in the rat intestinal mucosa.
Topics: Animals; Cadaverine; Chromatography, Thin Layer; DNA; Glucosidases; Indicators and Reagents; Intestinal Mucosa; Male; Polyamines; Proteins; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1986 |
Relationship of erythrocyte polyamine levels and growth rate of transplantable tumors in rats.
Topics: Animals; Colonic Neoplasms; Fibrosarcoma; Hematocrit; Male; Neoplasms, Experimental; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1986 |
Control of ornithine decarboxylase in Chinese hamster ovary cells by polyamines. Translational inhibition of synthesis and acceleration of degradation of the enzyme by putrescine, spermidine, and spermine.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Line; Cricetinae; Female; Mutation; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Ovary; Polyamines; Protein Biosynthesis; Putrescine; RNA, Messenger; Spermidine; Spermine | 1986 |
[Detection of urinary polyamine by a new enzymatic differential assay. (I). Fundamental study on a new enzymatic differential assay].
Topics: Diamines; Humans; Methods; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Spermidine; Spermine; Substrate Specificity | 1986 |
[Detection of urinary polyamine by a new enzymatic differential assay. (II). Comparison with conventional method].
Topics: Chromatography, High Pressure Liquid; Diamines; Humans; Methods; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Reagent Kits, Diagnostic; Spermidine; Spermine | 1986 |
High ornithine decarboxylase activity and polyamine levels in human colorectal neoplasia.
Topics: Adenocarcinoma; Cell Differentiation; Colonic Neoplasms; Humans; Intestinal Mucosa; Intestinal Polyps; Ornithine Decarboxylase; Polyamines; Rectal Neoplasms; Spermidine; Spermine | 1986 |
Modulation of ornithine decarboxylase activity and ornithine decarboxylase-antizyme complex in rat heart by hormone and putrescine treatment.
Topics: Animals; Dexamethasone; Enzyme Inhibitors; Female; Heart; Isoproterenol; Male; Mathematics; Molecular Weight; Myocardium; Ornithine Decarboxylase; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Time Factors | 1986 |
Effect of polyamines on perfused rat heart contractility.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; In Vitro Techniques; Myocardial Contraction; Perfusion; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1986 |
Fetal calf serum-mediated toxicity of human polyamines to lymphocytes.
Topics: Aging; Cell Survival; Humans; In Vitro Techniques; Lymphocytes; Mitogens; Polyamines; Putrescine; Spermidine; Spermine | 1986 |
N1-monoacetylation abolishes the inhibitory effect of spermine and spermidine in the reticulocyte lysate translation system.
Topics: Animals; Cell-Free System; Kinetics; Myocardium; Protein Biosynthesis; Rabbits; Reticulocytes; RNA, Messenger; Spermidine; Spermine; Structure-Activity Relationship | 1986 |
Putrescine metabolism in human brain tumors.
Topics: Astrocytoma; Brain Neoplasms; Humans; In Vitro Techniques; Meningioma; Neurilemmoma; Putrescine; Spermidine; Spermine | 1986 |
Polyamine-phospholipid interaction probed by the accessibility of the phospholipid sn-2 ester bond to the action of phospholipase A2.
Topics: Animals; Kinetics; Pancreas; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Polyamines; Spermidine; Spermine; Substrate Specificity; Swine | 1986 |
A left-handed (Z) conformation of poly(dA-dC).poly(dG-dT) induced by polyamines.
Topics: Base Sequence; Circular Dichroism; Nucleic Acid Conformation; Osmolar Concentration; Polyamines; Polydeoxyribonucleotides; Putrescine; Spermidine; Spermine | 1986 |
Removal of 239Pu from mice with 3,4,3 LICAM(C) or N,N',N'',N'''-tetra-(2,3-dihydroxybenzoyl)-spermine.
Topics: Animals; Bone and Bones; Chelating Agents; Femur; Kidney; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Pentetic Acid; Plutonium; Spermidine; Spermine; Structure-Activity Relationship; Tissue Distribution | 1986 |
Polyamine localization and biosynthesis in chemically fractionated rat retina.
Topics: Adenosylmethionine Decarboxylase; Animals; Female; Male; Ornithine Decarboxylase; Photoreceptor Cells; Polyamines; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Retina; Spermidine; Spermine; Tissue Distribution | 1986 |
Changes of serum-induced ornithine decarboxylase activity and putrescine content during aging of IMR-90 human diploid fibroblasts.
Topics: Blood; Cell Survival; Enzyme Activation; Fibroblasts; Humans; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine; Time Factors | 1986 |
[Detection of polyamines by a new enzymatic differential assay. (4). Fundamental study on a new enzymatic differential assay of blood].
Topics: Chromatography, High Pressure Liquid; Diamines; Humans; Methods; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Spermidine; Spermine | 1986 |
[Detection of polyamines by a new enzymatic differential assay. (5). Studies on polyamine in the blood of patients with malignant genitourinary diseases].
Topics: Diamines; Humans; Male; Polyamines; Spermidine; Spermine; Urologic Neoplasms | 1986 |
Exchange of H1 histone depends on aggregation of chromatin, not simply on ionic strength.
Topics: Calcium; Cations; Chemical Precipitation; Chromatin; Drug Interactions; HeLa Cells; Histones; Humans; Magnesium; Osmolar Concentration; Sodium; Solubility; Spermidine; Spermine | 1986 |
Characterization of Trypanosoma brucei brucei S-adenosyl-L-methionine decarboxylase and its inhibition by Berenil, pentamidine and methylglyoxal bis(guanylhydrazone).
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Carboxy-Lyases; Diminazene; Male; Mitoguazone; Pentamidine; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Trypanocidal Agents; Trypanosoma brucei brucei | 1986 |
Regulation of spermidine/spermine N1-acetyltransferase in L6 cells by polyamines and related compounds.
Topics: Acetyltransferases; Cells, Cultured; Enzyme Induction; Mitoguazone; Polyamines; Spermidine; Spermine | 1986 |
Polyamines stimulate mitochondrial calcium transport in rat brain.
Topics: Animals; Biological Transport; Brain; Calcium; Calcium Radioisotopes; Kinetics; Male; Mitochondria; Polyamines; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Spermidine; Spermine; Succinates; Succinic Acid | 1987 |
Uptake of exogenous spermidine by rat lungs perfused in situ.
Topics: Animals; Biological Transport; Kinetics; Lung; Male; Mitoguazone; Perfusion; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1987 |
Structural alterations and stabilization of rabbit uterine estrogen receptors by natural polyamines.
Topics: Animals; Estradiol; Female; Kinetics; Osmolar Concentration; Putrescine; Rabbits; Receptors, Estrogen; Spermidine; Spermine; Uterus | 1987 |
Comparison of the effects of polyamines on the activities of RNA polymerases from murine normal tissues and transplantable tumors.
Topics: Animals; DNA-Directed RNA Polymerases; Kidney; Kinetics; Liver; Mice; Neoplasms, Experimental; RNA Polymerase I; RNA Polymerase II; RNA Polymerase III; Spermidine; Spermine; Spleen | 1986 |
Higher order folding of chromatin is induced in different ways by monovalent and by bivalent cations.
Topics: Animals; Calcium; Cations, Divalent; Cattle; Chromatin; Kinetics; Magnesium; Potassium; Sodium; Spermidine; Spermine; Thymus Gland | 1987 |
Inhibition of translation of mRNAs for ornithine decarboxylase and S-adenosylmethionine decarboxylase by polyamines.
Topics: Adenosylmethionine Decarboxylase; Albumins; Animals; Carboxy-Lyases; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Molecular Weight; Ornithine Decarboxylase; Protein Biosynthesis; Rats; Reticulocytes; RNA, Messenger; Spermidine; Spermine | 1987 |
Effect of methylglyoxal bis(guanylhydrazone) on hepatic, heart and skeletal muscle mitochondrial carnitine palmitoyltransferase and beta-oxidation of fatty acids.
Topics: Acyltransferases; Animals; Binding, Competitive; Carnitine; Carnitine O-Palmitoyltransferase; Diphenylhexatriene; Fatty Acids; Female; Fluorescence Polarization; Intracellular Membranes; Kinetics; Male; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Mitoguazone; Muscles; Oxidation-Reduction; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1987 |
Effects of polyamines on the mechanical and electrical activities of the isolated circular muscle of rat uterus.
Topics: Animals; Cadaverine; Electric Conductivity; Electric Stimulation; Female; In Vitro Techniques; Myometrium; Polyamines; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Uterine Contraction | 1985 |
Hormone-independent polyamine metabolism of squamous cell carcinoma of the prostate.
Topics: Adenosylmethionine Decarboxylase; Androgens; Animals; Carcinoma, Squamous Cell; Castration; Cyproterone; Estradiol; Estrogens; Hormones; Male; Neoplasm Transplantation; Ornithine Decarboxylase; Polyamines; Prostatic Neoplasms; Putrescine; Rats; Rats, Inbred F344; Spermidine; Spermine; Testosterone | 1985 |
RecA protein rapidly crystallizes in the presence of spermidine: a valuable step in its purification and physical characterization.
Topics: Crystallization; Escherichia coli; Kinetics; Microscopy, Electron; Putrescine; Rec A Recombinases; Spermidine; Spermine | 1985 |
Relation of red cell membrane properties to invasion by Plasmodium falciparum.
Topics: Adult; Cholesterol; Erythrocyte Membrane; Humans; Malaria; Membrane Lipids; Plasmodium falciparum; Putrescine; Spermidine; Spermine | 1985 |
Inhibition of carcinogenesis by alpha-difluoromethylornithine in heterotopically transplanted rat urinary bladders.
Topics: Animals; Eflornithine; Male; Methylnitrosourea; Ornithine; Putrescine; Rats; Rats, Inbred F344; Spermidine; Spermine; Urinary Bladder; Urinary Bladder Neoplasms | 1985 |
Polyamine reutilization and turnover in brain.
Topics: Alkynes; Aminocaproates; Animals; Brain; Brain Chemistry; Eflornithine; Male; Mice; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Spermidine; Spermine; Vigabatrin | 1985 |
Excretion of polyamines by humans following inhibition of diamine oxidase.
Topics: Amine Oxidase (Copper-Containing); Cadaverine; Creatine; Guanidines; Humans; Male; Polyamines; Putrescine; Spermidine; Spermine | 1985 |
Regulation of S-adenosylmethionine decarboxylase activity in rat liver and prostate.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cycloheximide; Eflornithine; Half-Life; Immunosorbent Techniques; Kinetics; Liver; Male; Mitoguazone; Molecular Weight; Ornithine; Prostate; Putrescine; Rabbits; Radioimmunoassay; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1985 |
Stimulation of the cyclic AMP-dependent protein kinase-catalyzed phosphorylation of phosphorylase kinase by micromolar concentrations of spermine.
Topics: Animals; Glycogen Synthase; Histones; Kinetics; Muscles; Phosphorus Radioisotopes; Phosphorylase Kinase; Phosphorylation; Protein Kinases; Putrescine; Rabbits; Spermidine; Spermine | 1985 |
Effects of difluoromethylornithine on proliferation, polyamine content and plating efficiency of cultured human carcinoma cells.
Topics: Cell Division; Cell Line; Clone Cells; Eflornithine; Female; Humans; Kinetics; Neoplasms; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1985 |
Correlation between outer-membrane lysis and susceptibility of mitochondria to inhibition by adriamycin and polyamines.
Topics: Animals; Cations; Digitonin; Doxorubicin; Intracellular Membranes; Mitochondria, Liver; Osmolar Concentration; Permeability; Polyamines; Rats; Spermidine; Spermine; Succinates; Uncoupling Agents | 1986 |
A possible role for polyamines in cartilage in the mechanism of calcification.
Topics: Alkaline Phosphatase; Animals; Calcification, Physiologic; Cartilage; Cattle; Collagen; Osteogenesis; Proteoglycans; Putrescine; Scapula; Spermidine; Spermine | 1986 |
Effects of polyamines on the thermotropic behaviour of dipalmitoylphosphatidylglycerol.
Topics: Calcium; Hydrogen-Ion Concentration; Models, Biological; Phosphatidylglycerols; Polyamines; Spermidine; Spermine; Thermodynamics | 1986 |
Elevated levels of free putrescine and N1-acetylspermidine in cyst fluids of malignant brain tumours.
Topics: Brain; Brain Neoplasms; Cysts; Humans; Putrescine; Spermidine; Spermine | 1986 |
Polyamine oxidase activity in carcinoma-bearing human breast: significant decreased activity in carcinomatous tissue.
Topics: Breast; Breast Neoplasms; Carcinoma; Female; Humans; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Spermine | 1986 |
Altered polyamine metabolism in Chinese hamster cells growing in a defined medium.
Topics: Adenosylmethionine Decarboxylase; Animals; Blood; Cell Count; Cell Division; Cell Line; Cricetinae; Culture Media; Female; Ornithine; Ornithine Decarboxylase; Ovary; Polyamines; Putrescine; Spermidine; Spermine | 1986 |
[Effect of blood serum proteins and glucose on the polyamine content of the liver of rats with Guérin's carcinoma].
Topics: Animals; Blood Proteins; Drug Evaluation, Preclinical; Glucose; Liver; Neoplasm Transplantation; Neoplasms, Experimental; Polyamines; Putrescine; Rats; Spermidine; Spermine; Time Factors | 1986 |
Association constants for the interaction of double-stranded and single-stranded DNA with spermine, spermidine, putrescine, diaminopropane, N1- and N8-acetylspermidine, and magnesium: determination from analysis of the broadening of thermal denaturation c
Topics: Animals; Cattle; Diamines; DNA; DNA, Single-Stranded; Electronic Data Processing; Hot Temperature; Ligands; Magnesium; Nucleic Acid Denaturation; Polyamines; Putrescine; Spermidine; Spermine; Thymus Gland | 1986 |
Specific inhibition of polyamine oxidase in vivo is a method for the elucidation of its physiological role.
Topics: Animals; Brain; Carbon Tetrachloride; Dose-Response Relationship, Drug; Kidney; Kinetics; Liver; Male; Mice; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine; Spermine | 1985 |
Alterations of polyamines in body fluids during pregnancy in rats.
Topics: Animals; Body Fluids; Chromatography, High Pressure Liquid; Estradiol; Female; Polyamines; Pregnancy; Pregnancy, Animal; Progesterone; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1985 |
Limited blood-brain barrier transport of polyamines.
Topics: Adenosine; Animals; Arginine; Binding, Competitive; Biological Transport; Blood-Brain Barrier; Brain; Choline; Diffusion; Kinetics; Leucine; Male; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1985 |
Carrier-mediated uptake of methylglyoxal bis(guanylhydrazone) by rat lungs perfused in situ.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Guanidines; Kinetics; Lung; Male; Mitoguazone; Perfusion; Pulmonary Circulation; Putrescine; Rats; Rats, Inbred Strains; Serotonin; Spermidine; Spermine; Time Factors | 1985 |
Inhibition of human neutrophil locomotion by the polyamine oxidase-polyamine system.
Topics: Acrolein; Ammonia; Cell Movement; Cell Survival; Cells, Cultured; Chemotaxis, Leukocyte; Humans; Hydrogen Peroxide; Neutrophils; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Spermidine; Spermine | 1985 |
An enzymatic differential assay for urinary diamines, spermidine, and spermine.
Topics: Diamines; Humans; Neoplasms; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Spermine | 1985 |
Polyamine levels in gynecologic malignancies.
Topics: Adult; Aged; Cadaverine; Chromatography, High Pressure Liquid; Female; Genital Neoplasms, Female; Humans; Middle Aged; Ovarian Neoplasms; Polyamines; Putrescine; Spermidine; Spermine; Time Factors; Uterine Cervical Neoplasms; Uterine Neoplasms | 1985 |
Distribution of polyamines in human epidermis.
Topics: Female; Humans; Polyamines; Putrescine; Skin; Spermidine; Spermine | 1985 |
The binding of spermine to polynucleotides and complementary oligonucleotides at near physiological ionic strength.
Topics: Base Sequence; Binding, Competitive; Dialysis; Kinetics; Polyribonucleotides; Putrescine; Spermidine; Spermine; Structure-Activity Relationship | 1985 |
Dicyclohexylamine effects on HTC cell polyamine content and ornithine decarboxylase activity.
Topics: Animals; Cell Division; Cells, Cultured; Cyclohexylamines; Liver Neoplasms, Experimental; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1985 |
Inhibition of the uptake of benzo[a]pyrene in cells by polyamines.
Topics: Animals; Benzo(a)pyrene; Biological Transport, Active; Cells, Cultured; Culture Media; Humans; Polyamines; Putrescine; Spermidine; Spermine | 1985 |
Renal polyamine metabolism in rats with renovascular hypertension.
Topics: Adrenal Glands; Animals; Hypertension, Renovascular; Kidney; Male; Ornithine Decarboxylase; Putrescine; Rats; Rats, Inbred Strains; Renal Artery; Spermidine; Spermine; Time Factors | 1985 |
Effect of polyamines on hemoglobin and globin chain synthesis.
Topics: Globins; Hemoglobins; Humans; In Vitro Techniques; Polyamines; Putrescine; Reticulocytes; Spermidine; Spermine | 1985 |
[Mechanisms of the effect of polyamines on the complex-forming ability of blood plasma ribonucleases].
Topics: Animals; Blood Proteins; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Molecular Weight; Polyamines; Protein Binding; Rats; Ribonucleases; Spermidine; Spermine; Time Factors; Ultrafiltration | 1985 |
Pattern of human blood spermidine and spermine in prematurity.
Topics: Female; Humans; Infant, Newborn; Infant, Premature; Male; Pregnancy; Spermidine; Spermine | 1985 |
A simplified method for isocratic HPLC analysis of polyamines.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Polyamines; Putrescine; Rats; Spermidine; Spermine; Tissue Distribution | 1985 |
Concentrations of polyamines in umbilical blood.
Topics: Embryonic and Fetal Development; Erythrocytes; Erythropoiesis; Female; Fetal Blood; Fetus; Gestational Age; Humans; Infant, Newborn; Plasma; Polyamines; Pregnancy; Putrescine; Spermidine; Spermine | 1985 |
Determination of the polyamine content of rat heart mitochondria by the use of heparin-sepharose.
Topics: Animals; Chromatography, Ion Exchange; Heparin; In Vitro Techniques; Mitochondria, Heart; Polyamines; Putrescine; Rats; Sepharose; Spermidine; Spermine | 1985 |
Induction of spermidine/spermine N1-acetyltransferase by methylglyoxal bis(guanylhydrazone).
Topics: Acetyltransferases; Animals; Enzyme Induction; Female; Kidney; Kinetics; Liver; Mitoguazone; Organ Specificity; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Spleen | 1985 |
Polyamines and putreanine relax respiratory tract smooth muscle in the guinea-pig.
Topics: Amino Acids, Diamino; Animals; Guinea Pigs; In Vitro Techniques; Male; Methacholine Compounds; Muscle Relaxation; Muscle, Smooth; Ouabain; Polyamines; Potassium Chloride; Propranolol; Spermidine; Spermine; Trachea | 1985 |
Changes in polyamine synthesis and concentrations during chick embryo development.
Topics: Adenosylmethionine Decarboxylase; Age Factors; Animals; Chick Embryo; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Tissue Distribution | 1985 |
Effect of polyamines on perfused rat heart contractility.
Topics: Animals; In Vitro Techniques; Myocardial Contraction; Perfusion; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1985 |
The incorporation of radiolabeled polyamines and methionine into turnip yellow mosaic virus in protoplasts from infected plants.
Topics: Brassica; Carbon Radioisotopes; Methionine; Mosaic Viruses; Plants; Polyamines; Protoplasts; Putrescine; Spermidine; Spermine | 1985 |
Induction of spermidine/spermine N1-acetyltransferase in rat tissues by polyamines.
Topics: Acetyltransferases; Animals; Dose-Response Relationship, Drug; Enzyme Induction; Female; Kidney; Liver; Lung; Polyamines; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1985 |
The effect of polyamines on tubulin assembly.
Topics: Animals; Brain Chemistry; Cattle; Cold Temperature; Guanosine Triphosphate; Microscopy, Electron; Microtubule-Associated Proteins; Microtubules; Nephelometry and Turbidimetry; Polyamines; Polymers; Solubility; Spermidine; Spermine; Tubulin | 1985 |
Elevation of monoacetylated polyamines in human breast cancers.
Topics: Breast Neoplasms; Female; Humans; Polyamines; Prognosis; Putrescine; Spermidine; Spermine | 1985 |
Amine production by Leishmania mexicana.
Topics: Amines; Ammonia; Animals; Culture Media; Leishmania mexicana; Putrescine; Spermidine; Spermine; Time Factors; Urea | 1985 |
Some pharmacological properties of the polyamines spermine and spermidine--a re-appraisal.
Topics: Aerosols; Amobarbital; Animals; Behavior, Animal; Body Temperature; Depression, Chemical; Duodenum; Female; Guinea Pigs; Histamine; Histamine Release; Ileum; In Vitro Techniques; Injections, Intraperitoneal; Male; Mice; Motor Activity; Muscle Contraction; Polyamines; Rabbits; Rats; Rats, Inbred Strains; Sleep; Spermidine; Spermine; Uterus | 1972 |
Ornithine decarboxylase activity and polyamine synthesis during kidney hypertrophy.
Topics: Animals; Carboxy-Lyases; Dactinomycin; Depression, Chemical; Electrophoresis, Paper; Hydrocortisone; Hypertrophy; In Vitro Techniques; Kidney; Kidney Diseases; Nephrectomy; Ornithine; Putrescine; Rats; Spermidine; Spermine; Stimulation, Chemical | 1972 |
Ornithine decarboxylase and polyamines in silkmoth pupal tissues: effects of ecdysone and injury.
Topics: Adipose Tissue; Animals; Carbon Isotopes; Carboxy-Lyases; Cycloheximide; Dactinomycin; Ecdysone; Female; Insecta; Male; Ornithine; Pupa; Putrescine; Spermidine; Spermine; Time Factors; Wings, Animal | 1973 |
Müller WE,+MULLER WE, Zahn RK:Action of bleomycin on programmed synthesis. Influence on enzymatic DNA, RNA and protein synthesis.
Topics: Animals; Antibiotics, Antineoplastic; Binding, Competitive; Bleomycin; Dithiothreitol; DNA; DNA Nucleotidyltransferases; DNA-Directed RNA Polymerases; DNA, Bacterial; Embryo, Nonmammalian; Escherichia coli; Fishes; Mercaptoethanol; Protein Biosynthesis; RNA, Bacterial; Sea Urchins; Spermidine; Spermine; Templates, Genetic; Thymine Nucleotides; Tritium | 1973 |
Polyamines.
Topics: Animals; Cell Differentiation; DNA-Directed RNA Polymerases; Humans; Mammals; Methylation; Neoplasms; Polyamines; Putrescine; RNA; RNA, Messenger; RNA, Transfer; Spermidine; Spermine | 1973 |
Effect of polyamines on the binding of dihydrostreptomycin and N-acetylphenylalanyl-tRNA to ribosomes from Escherichia coli.
Topics: Ammonium Chloride; Binding Sites; Dihydrostreptomycin Sulfate; Escherichia coli; Magnesium; Micropore Filters; Phenylalanine; Polyamines; Putrescine; Ribosomes; RNA, Transfer; Spermidine; Spermine; Temperature | 1973 |
[Stimulation of gene activities by polyamines. An autoradiographic study with giant chromosones of Chironomus thummi (author's transl)].
Topics: Animals; Chromatography, Thin Layer; Chromosomes; Histocytochemistry; Insecta; Larva; Magnesium; Putrescine; RNA; Salivary Glands; Spermidine; Spermine; Staining and Labeling; Tritium; Uridine | 1974 |
Proceedings: Effect of polyamines on aminoacylation of tRNA from Phasaeolus vulgaris.
Topics: Amino Acyl-tRNA Synthetases; Leucine; Magnesium; Plants; Putrescine; RNA, Transfer; Spermidine; Spermine; Transfer RNA Aminoacylation | 1974 |
An attempt to identify putative neurotransmitter molecules in the central nervous system of the snail.
Topics: Amines; Amino Acids; Aminobutyrates; Animals; Brain Chemistry; Central Nervous System; Chromatography; Dihydroxyphenylalanine; Dopamine; Epinephrine; Ganglia; Neurotransmitter Agents; Norepinephrine; Putrescine; Serotonin; Snails; Spermidine; Spermine; Tryptamines; Tyramine | 1973 |
The combined effect of polyamines and antibiotics against resistant strains of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Drug Synergism; Penicillin Resistance; Penicillins; Polyamines; Putrescine; Spermidine; Spermine; Staphylococcus; Streptomycin; Tetracycline | 1972 |
Polyamines and polyamine-metabolizing enzyme activities in human semen.
Topics: Amine Oxidase (Copper-Containing); Carbon Radioisotopes; Carboxy-Lyases; Chromatography, Gel; Glyoxal; Humans; Hydrogen-Ion Concentration; Isoniazid; Kinetics; Male; Propylamines; Putrescine; S-Adenosylmethionine; Semen; Semicarbazides; Spermatozoa; Spermidine; Spermine; Time Factors; Transferases | 1973 |
Polyamine levels during growth, sporulation, and spore germination of Bacillus megaterium.
Topics: Bacillus megaterium; Cadaverine; Carbon Radioisotopes; Chloramphenicol; Dactinomycin; Electrophoresis, Paper; Micropore Filters; Polyamines; Putrescine; RNA, Bacterial; Spermidine; Spermine; Spores, Bacterial; Time Factors | 1974 |
[Temperature denaturation of Salmonella pullorum ribosomes in the presence of certain antibiotics and other biologically active substances].
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cell Fractionation; Centrifugation, Density Gradient; Chloramphenicol; Depression, Chemical; Drug Resistance, Microbial; Edetic Acid; Erythromycin; Lipopolysaccharides; Polyamines; Ribosomes; RNA, Ribosomal; Salmonella; Spectrophotometry, Ultraviolet; Spermidine; Spermine; Stimulation, Chemical; Temperature; Tetracycline; Ultracentrifugation | 1974 |
Multiple control of N-acetylglutamate synthetase from Pseudomonas aeruginosa: synergistic inhibition by acetylglutamate and polyamines.
Topics: Acetyl Coenzyme A; Acetyltransferases; Arginine; Cadaverine; Carbon Radioisotopes; Coenzyme A; Diamines; Drug Synergism; Glutamates; Kinetics; Polyamines; Propane; Pseudomonas aeruginosa; Putrescine; Spermidine; Spermine | 1974 |
Spermidine biosynthesis during germination and subsequent vegetative growth of Bacillus megaterium spores.
Topics: Arginine; Bacillus megaterium; Canavanine; Carbon Radioisotopes; Carboxy-Lyases; Depression, Chemical; Ornithine; Putrescine; Spermidine; Spermine; Spores, Bacterial; Time Factors; Tritium | 1974 |
Polyamine synthesis during initial phases of stress-induced cardiac hypertrophy.
Topics: Adaptation, Physiological; Animals; Butylamines; Carboxy-Lyases; Cardiomegaly; Heart Ventricles; Methionine; Myocardium; Organ Size; Ornithine; Polyamines; Pulmonary Artery; Pyridoxal Phosphate; Rabbits; RNA; S-Adenosylmethionine; Spermidine; Spermine; Stress, Physiological | 1971 |
Magnesium and polyamine levels in Neurospora crassa mycelia.
Topics: Culture Media; DNA; Edetic Acid; Fluorometry; Magnesium; Neurospora crassa; Polyamines; Ribosomes; RNA; Spermidine; Spermine | 1971 |
Polyamine biogenesis in left ventricle of the rat heart after aortic constriction.
Topics: Animals; Aorta; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Cardiomegaly; Constriction; Decarboxylation; Female; Heart Ventricles; Male; Myocardium; Organ Size; Ornithine; Polyamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine; Stress, Mechanical | 1972 |
Inhibition of phospholipase A-induced swelling of mitochondria by local anesthetics and related agents.
Topics: 4-Aminobenzoic Acid; Amines; Anesthetics, Local; Animals; Chlorpromazine; Dibucaine; Fatty Acids; Fatty Acids, Nonesterified; Kinetics; Lysophosphatidylcholines; Mitochondria; Mitochondrial Swelling; Phospholipases; Promethazine; Propranolol; Rats; Snakes; Spermidine; Spermine; Time Factors; Venoms | 1971 |
Polyamine and nucleic acid metabolism in myocardial hypertrophy of the overloaded heart.
Topics: Animals; Cardiomegaly; Cell Nucleus; Formates; Guinea Pigs; Heart; Male; Mitochondria; Monoamine Oxidase; Myocardium; Organ Size; Perfusion; Physical Exertion; Putrescine; Rats; Ribose; Ribosomes; RNA; Spermidine; Spermine; Swimming; Time Factors | 1974 |
Influence of polyamines on two bivalent-cation-activated ATPases.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Autoanalysis; Binding Sites; Calcium; Enzyme Activation; Erythrocytes; Humans; Kidney; Kinetics; Magnesium; Putrescine; Spermidine; Spermine; Swine; Ultracentrifugation | 1973 |
Polyamines and noradrenaline following myocardial hypertrophy.
Topics: Animals; Cardiomegaly; Norepinephrine; Rabbits; Spermidine; Spermine | 1971 |
Actions of polyamines on lipid and glucose metabolism of fat cells.
Topics: Adipose Tissue; Animals; Biological Transport; Butyrates; Carbon Dioxide; Carbon Isotopes; Cells; Cells, Cultured; Cyclic AMP; Depression, Chemical; Epididymis; Epinephrine; Ethers; Glucose; Glycerol; Insulin; Kinetics; Lipid Metabolism; Male; Metabolism; Phloretin; Polyamines; Rats; Spermidine; Spermine; Stimulation, Chemical; Theophylline | 1971 |
Catalysts for the polymerization of adenosine cyclic 2',3'-phosphate on a poly (U) template.
Topics: Adenine Nucleotides; Alkaline Phosphatase; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Paper; Cyclic AMP; Ethylenediamines; Freezing; Hydrogen-Ion Concentration; Kinetics; Magnesium; Nucleic Acid Conformation; Polyamines; Polynucleotides; Spectrophotometry; Spermidine; Spermine; Temperature; Templates, Genetic; Uracil Nucleotides | 1971 |
Mammalian cell fusion. IV. Regulation of chromosome formation from interphase nuclei by various chemical compounds.
Topics: Calcium Chloride; Cell Fusion; Chromatin; Chromosomes; Cyclic AMP; DNA; Edetic Acid; Estradiol; HeLa Cells; Heparin; Hybrid Cells; Magnesium; Mitosis; Polyamines; Putrescine; Spermidine; Spermine | 1971 |
Aminoacyl transfer RNA formation. II. Comparison of the mechanisms of aminoacylations stimulated by polyamines and Mg 2+ .
Topics: Acylation; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Carbon Isotopes; Catalysis; Chromatography, Ion Exchange; Diphosphates; Escherichia coli; Hydroxamic Acids; Isoleucine; Kinetics; Magnesium; Phenylalanine; Phosphorus Isotopes; Polyamines; Putrescine; RNA, Transfer; Spermidine; Spermine; Transfer RNA Aminoacylation; Valine | 1972 |
Imbalance in ornithine metabolism in hepatomas of different growth rates as expressed in formation of putrescine, spermidine, and spermine.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Electrophoresis, Paper; Liver; Liver Neoplasms; Male; Neoplasm Transplantation; Neoplasms, Experimental; Ornithine; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Transplantation, Homologous | 1972 |
The polyamine content in two slow-growing rat hepatomas.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Liver Neoplasms; Male; Ornithine; Polyamines; Rats; Spermidine; Spermine | 1972 |
Aminoacyl transfer RNA formation. 3. Mechanism of aminoacylation stimulated by polyamines.
Topics: Acetates; Acylation; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Amino Acyl-tRNA Synthetases; Cadaverine; Carbon Isotopes; Chromatography, Gel; Chromatography, Ion Exchange; Diphosphates; Escherichia coli; Guanidines; Isoleucine; Magnesium; Phosphorus Isotopes; Polyamines; RNA, Transfer; Spermidine; Spermine; Structure-Activity Relationship | 1973 |
Polycation inhibition of chloroplast photosystem I.
Topics: Amines; Biological Transport; Cell Membrane; Chloroplasts; Cytochrome c Group; Detergents; Histones; Lysine; Molecular Weight; Muramidase; Palmitic Acids; Peptides; Phosphatidylcholines; Photophosphorylation; Photosynthesis; Polymers; Ribonucleases; Species Specificity; Spermidine; Spermine; Triglycerides; Trypsin | 1973 |
Inhibition of pyridoxal kinase from rat liver in vitro by aromatic and aliphatic amines.
Topics: Amines; Amino Acids; Animals; Binding, Competitive; Cadaverine; Chronic Disease; Female; Histamine; Liver; Liver Diseases; Phosphotransferases; Putrescine; Pyridoxal; Pyridoxine; Rats; Serotonin; Spermidine; Spermine; Structure-Activity Relationship; Tryptamines; Tyramine | 1973 |
Polyamines and tumor cells: effect of transformation of chick embryo fibroblasts by Rous sarcoma virus on polyamine levels.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Chromatography, Thin Layer; Culture Media; Dansyl Compounds; Fibroblasts; Neoplasm Proteins; Putrescine; Spermidine; Spermine; Time Factors | 1973 |
Polyamines in normal and in virus-transformed chick embryo fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Culture Media; Fibroblasts; Neoplasm Proteins; Polyamines; Proteins; Putrescine; RNA; RNA, Neoplasm; Spermidine; Spermine | 1974 |
Polyamine depletion of tumor tissue and subsequent elevation of spermidine in the sera of rats with 3924A hepatomas after 5-fluorouracil administration.
Topics: Animals; Carcinoma, Hepatocellular; Female; Fluorouracil; Liver; Liver Neoplasms; Neoplasms, Experimental; Polyamines; Putrescine; Rats; Spermidine; Spermine; Time Factors | 1974 |
Regulation of growth in vitro. I. Control of ornithine decarboxylase levels in untransformed and transformed mouse fibroblasts by serum.
Topics: Animals; Carbon Radioisotopes; Carboxy-Lyases; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Culture Techniques; Fibroblasts; Kinetics; Mice; Ornithine; Putrescine; Simian virus 40; Spermidine; Spermine; Time Factors; Trypsin | 1974 |
A method for the determination of polyamines in cerebrospinal fluid.
Topics: Autoanalysis; Cadaverine; Carbon Radioisotopes; Chromatography, Ion Exchange; Evaluation Studies as Topic; Glioblastoma; Humans; Medulloblastoma; Methods; Polyamines; Putrescine; Spermidine; Spermine | 1974 |
Studies of the insulin-like actions of polyamines on lipid and glucose metabolism in adipose tissue cells.
Topics: Adipose Tissue; Animals; Carbon Radioisotopes; Clostridium perfringens; Edetic Acid; Epididymis; Glucose; In Vitro Techniques; Insulin; Kinetics; Lipid Metabolism; Male; Neuraminidase; Polyamines; Proteins; Putrescine; Rats; Spermidine; Spermine; Structure-Activity Relationship; Time Factors; Trypsin | 1974 |
Increased polyamine concentrations in the cerebrospinal fluid of patients with brain tumors.
Topics: Adenoma, Acidophil; Adenoma, Chromophobe; Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Child; Child, Preschool; Cholesteatoma; Ependymoma; Female; Glioblastoma; Humans; Male; Medulloblastoma; Meningioma; Middle Aged; Neurilemmoma; Pituitary Neoplasms; Putrescine; Spermidine; Spermine; Teratoma | 1974 |
Blood histamine, polyamines and the schizophrenias. Computer correlations of the low and high blood histamine types.
Topics: Computers; Diagnosis, Computer-Assisted; Electroencephalography; Female; Histamine; Humans; Male; MMPI; Polyamines; Psychiatric Status Rating Scales; Schizophrenia; Sex Factors; Spermidine; Spermine; Statistics as Topic; Uric Acid | 1970 |
Variation of the conformational states of Escherichia coli glutamine synthetase by interaction with different divalent cations.
Topics: Cadmium; Calcium; Catalysis; Cations, Divalent; Cobalt; Enzyme Activation; Escherichia coli; Glutamate-Ammonia Ligase; Glutamates; Hydrogen-Ion Concentration; Kinetics; Magnesium; Protein Conformation; Quaternary Ammonium Compounds; Spectrophotometry, Ultraviolet; Spermidine; Spermine; Tryptophan; Tyrosine | 1972 |
On the possible role of crystals in the origins of life. VII. The adsorption and polymerization of phosphoramidates by montmorillonite clay.
Topics: Adenosine; Adenosine Monophosphate; Adsorption; Amides; Ammonia; Biological Evolution; Chromatography, Paper; Crystallization; Electrophoresis, Paper; Magnesium; Phosphates; Polynucleotides; Sodium; Spermidine; Spermine | 1974 |
Evidence for the direct binding of polyamines to a ribonuclease that hydrolyzes ribonucleic acid at uridylic acid residues.
Topics: Amino Acids; Binding Sites; Carbon Radioisotopes; Cations, Divalent; Chromatography, Gel; Chromatography, Ion Exchange; Citrobacter; Escherichia; Guanine Nucleotides; Kinetics; Macromolecular Substances; Polynucleotides; Protein Binding; Putrescine; Ribonucleases; Spectrophotometry, Ultraviolet; Spermidine; Spermine; Structure-Activity Relationship; Tritium; Trypsin; Uracil Nucleotides | 1974 |
Necessity of polyamines for maximum isoleucyl-tRNA formation in a rat liver cell-free system.
Topics: Amino Acyl-tRNA Synthetases; Animals; Carbon Radioisotopes; Cell-Free System; Chromatography, Ion Exchange; Isoleucine; Liver; Magnesium; Phenylalanine; Polyamines; Putrescine; Rats; RNA, Transfer; Spermidine; Spermine; Transcription, Genetic; Ultrafiltration | 1974 |
Polyamine biosynthesis and vitamin B6 deficiency. Evidence for pyridoxal phosphate as coenzyme for S-adenosylmethionine decarboxylase.
Topics: Animals; Arginine; Brain; Carbon Radioisotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Enzyme Activation; Liver; Male; Organ Specificity; Ornithine; Polyamines; Putrescine; Pyridoxal Phosphate; Rats; S-Adenosylmethionine; Spermidine; Spermine; Ultracentrifugation; Vitamin B 6 Deficiency | 1974 |
RNA-synthesizing enzymes in healthy and TMV-infected tobacco leaves. Partial purification and characterization to tobacco polynucleotide phosphorylase.
Topics: Centrifugation, Density Gradient; Chromatography, Gel; Chromatography, Ion Exchange; Hydrogen-Ion Concentration; Kinetics; Magnesium; Manganese; Molecular Weight; Nicotiana; Phosphorus Radioisotopes; Plants; Plants, Toxic; Polyamines; Polyribonucleotide Nucleotidyltransferase; Putrescine; RNA; RNA, Viral; Spectrophotometry, Ultraviolet; Spermidine; Spermine; Time Factors; Tobacco Mosaic Virus; Transcription, Genetic; Ultracentrifugation | 1974 |
Comparative properties of rat liver and sea urchin eggs S-adenosyl-L-methionine decarboxylase.
Topics: Animals; Autoanalysis; Carbon Radioisotopes; Carboxy-Lyases; Chloromercuribenzoates; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Disc; Ethylmaleimide; Female; Iodoacetates; Liver; Molecular Weight; Organ Specificity; Ovum; Putrescine; Rats; S-Adenosylmethionine; Sea Urchins; Species Specificity; Spectrophotometry, Ultraviolet; Spermidine; Spermine | 1974 |
Inhibitors of histone methylation.
Topics: Animals; Biogenic Amines; Carbon Radioisotopes; Cattle; Deoxyribonucleases; Ethidium; Histones; Kinetics; Methylation; Methyltransferases; Phenethylamines; S-Adenosylmethionine; Spermidine; Spermine; Structure-Activity Relationship; Thymus Gland | 1974 |
The correlation of PHA induced polyamine changes in human lymphocytes with tritiated thymidine incorporation.
Topics: DNA; Humans; In Vitro Techniques; Isotope Labeling; Lectins; Lymphocytes; Osmolar Concentration; Polyamines; Putrescine; Spermidine; Spermine; Thymidine; Time Factors; Tritium | 1974 |
The in-vitro and in-vivo effects of polyamines on cardiac protein biosynthesis.
Topics: Amino Acyl-tRNA Synthetases; Aminoisobutyric Acids; Animals; Carbon Radioisotopes; Cell-Free System; Heart; In Vitro Techniques; Male; Myocardium; Perfusion; Phenylalanine; Polyamines; Protein Biosynthesis; Putrescine; Rats; RNA, Transfer; Spermidine; Spermine | 1974 |
Elevation of putrescine and spermidine in sera of patients with solid tumors.
Topics: Autoanalysis; Breast Neoplasms; Cadaverine; Carbon Radioisotopes; Carcinoma; Chromatography, Ion Exchange; Colonic Neoplasms; Female; Hodgkin Disease; Humans; Kidney Neoplasms; Melanoma; Neoplasms; Putrescine; Rectal Neoplasms; Sarcoma; Spermidine; Spermine | 1974 |
Spermidine as a possible mediator of glucocorticoid effect on milk protein synthesis in mouse mammary epithelium in vitro.
Topics: Aldosterone; Amidines; Animals; Carboxy-Lyases; Cell Differentiation; Epithelium; Female; Glyoxal; Hydrazones; Hydrocortisone; Insulin; Magnesium; Mammary Glands, Animal; Mice; Milk Proteins; Organ Culture Techniques; Pregnancy; Prolactin; S-Adenosylmethionine; Spermidine; Spermine; Time Factors | 1974 |
Enhancement of UDP-galactose:mucin galactosyltransferase activity by spermine.
Topics: Amines; Animals; Cadaverine; Cations, Divalent; Dogs; Enzyme Activation; Fetal Proteins; Galactose; Hexosyltransferases; Kinetics; Manganese; Mucins; Neuraminidase; Polyethylene Glycols; Putrescine; Sheep; Spermidine; Spermine; Submandibular Gland; Trachea; Uridine Diphosphate Sugars | 1974 |
Distribution of putrescine, spermidine, and spermine in rhesus monkey brain: decrease in spermidine and spermine concentrations in motor cortex after electrical stimulation.
Topics: Amygdala; Animals; Brain Chemistry; Cerebellar Cortex; Electric Stimulation; Hippocampus; Hypothalamus; Macaca mulatta; Male; Motor Cortex; Putrescine; Spermidine; Spermine | 1974 |
Hyperglycaemia produced by the polyamines spermine and spermidine.
Topics: Animals; Cerebral Ventricles; Cisterna Magna; Female; Hyperglycemia; Injections; Injections, Intravenous; Medulla Oblongata; Pentobarbital; Rabbits; Rats; Reserpine; Spermidine; Spermine; Stimulation, Chemical | 1974 |
Inhibition of DNA synthesis by methylglyoxal bis(guanylhydrazone) during lymphocyte transformation.
Topics: Aldehydes; Animals; DNA; Glyoxal; Guinea Pigs; Hydrazones; Lectins; Lymphocyte Activation; Lymphocytes; Putrescine; Spermidine; Spermine; Thymidine | 1974 |
Regulatory effects of polyamines on membrane-bound acetylcholinesterase.
Topics: Acetylcholinesterase; Allosteric Regulation; Animals; Cell Membrane; Cholinesterase Inhibitors; Electric Organ; Electrophorus; Enzyme Activation; Erythrocytes; Humans; Kinetics; Polyamines; Putrescine; Spermidine; Spermine | 1974 |
[Behavioral pharmacology of alkali metals. (3). Changes in polyamine levels in the brain and emotional behavior of aggressive mice originally isolated and returned to a group situation].
Topics: Aggression; Animals; Behavior, Animal; Brain; Brain Chemistry; Dopamine; Humans; Lithium; Male; Mice; Norepinephrine; Polyamines; Serotonin; Social Isolation; Spermidine; Spermine; Time Factors | 1974 |
Gas-chromatographic measurement of urinary polyamines in cancer patients.
Topics: Chromatography, Gas; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Methods; Polyamines; Prednisone; Putrescine; Spermidine; Spermine; Vincristine | 1973 |
Quantum chemical studies on drug actions. II. Quantum chemical data on derivatives of catechol, indole, imidazole amines and of spermine and spermidine.
Topics: 5-Hydroxytryptophan; Amines; Catecholamines; Catechols; Chemical Phenomena; Chemistry; Dopamine; Epinephrine; Fluorine; Hallucinogens; Histamine; Hydroxyindoleacetic Acid; Hydroxylation; Imidazoles; Indoles; Mandelic Acids; Norepinephrine; Normetanephrine; Phenethylamines; Quantum Theory; Serotonin; Spermidine; Spermine; Sulfhydryl Compounds; Tryptamines; Tryptophan; Tyramine | 1973 |
Interrelationships between polyamines and nucleic acids. IV. Autoradiographic localization of 3 H-putrescine and its metabolites in normal and degenerating peripheral nerves, and spinal ganglia.
Topics: Animals; Autoradiography; Electrophoresis; Ganglia, Spinal; Gels; Histocytochemistry; Histological Techniques; Male; Microscopy, Electron; Nerve Degeneration; Nucleic Acids; Peripheral Nerves; Polyamines; Putrescine; Rats; Rats, Inbred Strains; RNA; Sciatic Nerve; Spermidine; Spermine; Tritium | 1972 |
Purification and properties of mitochondrial deoxyribonucleic acid dependent ribonucleic acid polymerase from ovaries of Xenopus laevis.
Topics: Ammonium Sulfate; Animals; Chromatography, Ion Exchange; Dithiothreitol; DNA; Electrophoresis; Escherichia coli; Female; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Magnesium; Mitochondria; Molecular Weight; Osmolar Concentration; Ovary; Potassium Chloride; RNA Nucleotidyltransferases; Spermidine; Spermine; Templates, Genetic; Tritium; Ultracentrifugation; Xenopus | 1972 |
Partial purification and characterization of spermine synthase from rat brain.
Topics: Animals; Binding, Competitive; Brain; Carbon Isotopes; Carboxy-Lyases; Cations, Divalent; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cytosol; Escherichia coli; Feedback; Female; Hydrogen-Ion Concentration; Isoelectric Focusing; Kinetics; Propylamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine; Structure-Activity Relationship; Transferases | 1972 |
Assembly of Escherichia coli 50 S ribosomes from ribonucleic acid and protein components. I. Chemical and physical factors affecting the conformation of assembled particles.
Topics: Ammonium Chloride; Bacterial Proteins; Carbon Isotopes; Centrifugation, Zonal; Citrates; Escherichia coli; Hydrogen-Ion Concentration; Macromolecular Substances; Magnesium; Osmolar Concentration; Phenylalanine; Protein Biosynthesis; Protein Conformation; Ribosomes; RNA, Bacterial; RNA, Ribosomal; RNA, Transfer; Solubility; Species Specificity; Spermidine; Spermine; Urea | 1973 |
Ambiguity in a polypeptide-synthesizing extract from Saccharomyces cerevisiae.
Topics: Acylation; Amino Acyl-tRNA Synthetases; Carbon Isotopes; Cell Fractionation; Cell-Free System; Cytoplasm; Ethanol; Fungal Proteins; Hydrogen-Ion Concentration; Isoleucine; Leucine; Magnesium; Neomycin; Peptide Biosynthesis; Phenylalanine; Poly U; Protein Biosynthesis; RNA, Transfer; Saccharomyces cerevisiae; Serine; Spermidine; Spermine; Streptomycin; Temperature | 1973 |
Polyamine requirements of a conditional polyamine auxotroph of Escherichia coli.
Topics: Arginine; Cadaverine; Canavanine; Carbohydrate Metabolism; Carbon Isotopes; Culture Media; Densitometry; Escherichia coli; Glucose; Mutation; Ornithine; Osmolar Concentration; Polyamines; Putrescine; Spermidine; Spermine; Urease | 1973 |
Distinct effects of diamines, polyamines, and magnesium ions on the stability of lambda phage heads.
Topics: Cadaverine; Calcium; Coliphages; DNA, Viral; Drug Stability; Escherichia coli; Lysine; Magnesium; Mutation; Nucleic Acid Conformation; Ornithine; Polyamines; Propylamines; Putrescine; Spermidine; Spermine; Thymidine; Tritium; Viral Proteins | 1973 |
The mechanism of action of methionyl-tRNA synthetase from Escherichia coli. 1. Fluorescence studies on tRNAMet binding as a function of ligands, ions and pH.
Topics: Amino Acyl-tRNA Synthetases; Binding Sites; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methionine; Potassium Chloride; Protein Binding; Protein Conformation; RNA, Transfer; Spectrometry, Fluorescence; Spermidine; Spermine; Trypsin | 1973 |
The mechanism of action of methionyl-tRNA synthetase. 3. Ion requirements and kinetic parameters of the ATP-PPi exchange and methionine-transfer reactions catalyzed by the native and trypsin-modified enzymes.
Topics: Acylation; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Ammonium Chloride; Catalysis; Escherichia coli; Kinetics; Magnesium; Methionine; Potassium Chloride; Protein Binding; Protein Conformation; RNA, Transfer; Spectrometry, Fluorescence; Spermidine; Spermine; Structure-Activity Relationship; Trypsin | 1973 |
Polyamines and transfer RNA-methylation in mouse leukemic cells.
Topics: Animals; Binding Sites; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Paper; Chromatography, Thin Layer; Escherichia coli; Kinetics; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Putrescine; RNA, Transfer; Spermidine; Spermine; Time Factors; tRNA Methyltransferases; Ultracentrifugation | 1972 |
Quantitative determination of aliphatic diamines and polyamines by an automated liquid chromatography procedure.
Topics: Amino Acids, Diamino; Ammonia; Animals; Autoanalysis; Cadaverine; Chromatography, Ion Exchange; Diamines; Escherichia coli; Evaluation Studies as Topic; Glutathione; Humans; Liver; Methods; Mice; Microchemistry; Polyamines; Putrescine; Species Specificity; Spermidine; Spermine; Time Factors | 1973 |
[Structural and biochemical aspects of the effects of various media used for isolation and fractionation of mouse liver nuclei].
Topics: Animals; Calcium Chloride; Cell Nucleus; Centrifugation; Chlorides; Chromatin; Culture Media; Cytological Techniques; DNA; Heterochromatin; Liver; Magnesium; Mercaptoethanol; Methods; Mice; Microscopy, Electron; Phospholipids; Potassium Chloride; Proteins; RNA; Spermidine; Spermine; Tromethamine; Vibration | 1973 |
Characterization of aminoacyl transfer ribonucleic acid formation stimulated by polyamines.
Topics: Adenosine Triphosphate; Amino Acids; Amino Acyl-tRNA Synthetases; Carbon Radioisotopes; Cell-Free System; Chromatography, Ion Exchange; Escherichia coli; Isoleucine; Magnesium; Peptide Biosynthesis; Phenylalanine; Protein Binding; Putrescine; Ribosomes; RNA, Bacterial; RNA, Transfer; Spermidine; Spermine | 1972 |
Unfolding of yeast transfer ribonucleic acid species caused by addition of organic solvents and studied by circular dichroism.
Topics: Arsenicals; Buffers; Circular Dichroism; Crystallization; Dioxins; Ethanol; Glycols; Hexanols; Isoleucine; Magnesium; Nucleic Acid Conformation; Nucleic Acid Denaturation; Phenylalanine; RNA, Transfer; Saccharomyces cerevisiae; Serine; Sodium Chloride; Spectrophotometry, Ultraviolet; Spermidine; Spermine; Temperature; Tyrosine; Urea; Valine | 1974 |
Polyamine, magnesium and ribonucleic acid levels in steady-state cultures of the mould Aspergillus nidulans.
Topics: Aspergillus nidulans; Chromatography, Thin Layer; Culture Media; Magnesium; Polyamines; RNA; Spectrometry, Fluorescence; Spermidine; Spermine | 1974 |
Multiple transport components for putrescine in Escherichia coli.
Topics: Amino Acids; Azides; Biological Transport, Active; Cadaverine; Carbon Radioisotopes; Chromatography, Thin Layer; Culture Media; Diamines; Dinitrophenols; Escherichia coli; Glucose; Mutagens; Mutation; Nitrosoguanidines; Osmolar Concentration; Putrescine; Spectrophotometry; Spermidine; Spermine; Time Factors | 1974 |
[Effect of spermine, spermidine, dimethyl sulfoxide, sodium dodecylsulfate and sodium deoxycholate on bacterial resistance to certain antibiotics].
Topics: Anti-Bacterial Agents; Bacteriological Techniques; Chloramphenicol; Conjugation, Genetic; Culture Media; Deoxycholic Acid; Depression, Chemical; Dimethyl Sulfoxide; Drug Interactions; Drug Resistance, Microbial; Escherichia coli; Microbial Sensitivity Tests; Sodium; Sodium Dodecyl Sulfate; Spermidine; Spermine; Staphylococcus; Streptomycin; Tetracycline | 1974 |
Observations on the fluorometric assay of histamine. Spermidine and spermine in brain.
Topics: Animals; Brain Chemistry; Edetic Acid; Fluorometry; Histamine; Methods; Polyamines; Rats; Spectrometry, Fluorescence; Spermidine; Spermine; Temperature; Trichloroacetic Acid | 1972 |
The antibacterial action of canine prostatic fluid and human seminal plasma in an agar diffusion assay system.
Topics: Animals; Bacteria; Body Fluids; Dogs; Electrophoresis, Paper; Humans; Immunodiffusion; Male; Polysaccharides; Prostate; Semen; Spermidine; Spermine | 1973 |
Experimental modification of the "tertiary structure" of chromosomes in human lymphocytes: the effects of polyanionic substances and hypertonic salt solutions.
Topics: Cell Division; Chromatids; Chromosome Aberrations; Chromosomes; Culture Media; Edetic Acid; Humans; Hypertonic Solutions; Indicators and Reagents; Lymphocytes; Sodium Chloride; Spermidine; Spermine | 1973 |
The effect of formaldehyde and acetaldehyde on the swelling of cells of Pseudomonas aeruginosa in salt solutions and their interactions with amines and carboxylic acids.
Topics: Acetaldehyde; Amines; Biological Transport; Butanols; Carboxylic Acids; Cell Membrane Permeability; Chloroform; Diffusion; Drug Synergism; Ethylenediamines; Formaldehyde; Pseudomonas aeruginosa; Putrescine; Sodium Chloride; Spermidine; Spermine | 1973 |
Spermine synthesis in the uterus of the ovariectomized rat in response to oestradiol-17 .
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Castration; Chromatography, DEAE-Cellulose; Cycloheximide; Dactinomycin; Estradiol; Estrogen Antagonists; Female; Propylamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine; Uterus | 1972 |
Polyamine and nucleic acid concentrations in Ehrlich ascites carcinoma cells and liver of tumor-bearing mice at various stages of tumor growth.
Topics: Animals; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Polyamines; Putrescine; RNA, Neoplasm; Spermidine; Spermine | 1972 |
Polyamine biogenesis in the rat mammary gland during pregnancy and lactation.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Epithelial Cells; Epithelium; Female; Lactation; Mammary Glands, Animal; Ornithine; Polyamines; Pregnancy; Pregnancy, Animal; Putrescine; Rats; Ribonucleases; RNA; Spermidine; Spermine | 1972 |
S-adenosylmethionine decarboxylase from human prostate. Activation by putrescine.
Topics: Adenosine; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Enzyme Activation; Hot Temperature; Humans; Hydrazines; Hydrogen-Ion Concentration; Hydroxylamines; Isoniazid; Male; Methionine; Prostate; Putrescine; Spermidine; Spermine; Sulfhydryl Reagents | 1972 |
Antipolyamine antibodies and cell lysis. The inhibitory effect of putrescine.
Topics: Animals; Antibodies; Antigen-Antibody Reactions; Cell Membrane; Cells, Cultured; Complement System Proteins; Cytotoxicity Tests, Immunologic; Immune Sera; L Cells; Microscopy, Electron; Oxidoreductases, N-Demethylating; Polyamines; Putrescine; Rabbits; Spermidine; Spermine; Time Factors | 1972 |
Acrolein, a component of a universal cell-growth regulatory system: a theory.
Topics: Aldehydes; Alkenes; Animals; Antineoplastic Agents; Cells, Cultured; Cricetinae; Cyclophosphamide; Depression, Chemical; DNA; Electron Transport; Growth Substances; Ketones; Leucine; Models, Biological; Oxidation-Reduction; RNA; Spermidine; Spermine; Sulfhydryl Reagents; Thymidine; Thymus Gland; Tissue Extracts; Tritium; Uridine | 1972 |
Polyamines in human placenta.
Topics: Female; Humans; Placenta; Polyamines; Pregnancy; Putrescine; Spermidine; Spermine | 1972 |
The regional distribution of the polyamines spermidine and spermine in brain.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Chromatography, Ion Exchange; Dogs; Female; Humans; Rabbits; Rats; Sheep; Species Specificity; Spectrometry, Fluorescence; Spermidine; Spermine | 1973 |
Spermine and spermidine--polyamine components of human type 5 adenovirions.
Topics: Adenoviridae; Carbon Isotopes; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography, Thin Layer; Dansyl Compounds; HeLa Cells; Humans; Putrescine; Serotyping; Spectrophotometry; Spermidine; Spermine; Tritium; Ultracentrifugation; Virus Cultivation | 1973 |
Interrelationships between polyamines and nucleic acids. Changes of polyamine and nucleic acid concentrations in the growing fish brain (Salmo irideus Gibb.).
Topics: Animals; Brain; Brain Chemistry; Cell Division; Dansyl Compounds; DNA; Organ Size; Proteins; Putrescine; RNA; Salmonidae; Spermidine; Spermine | 1973 |
Effect of polyamines on polypeptide synthesis in rat liver cell-free system.
Topics: Animals; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Fluoresceins; In Vitro Techniques; Isoleucine; Leucine; Liver; Magnesium; Male; Microsomes, Liver; Peptide Biosynthesis; Phenylalanine; Polyamines; Polyribosomes; Rats; Spectrophotometry, Ultraviolet; Spermidine; Spermine; Subcellular Fractions | 1973 |
Polyamine metabolism in rat liver: effect of starvation and refeeding.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; DNA; Liver; Male; Ornithine; Polyamines; Proteins; Putrescine; Rats; RNA; S-Adenosylmethionine; Spermidine; Spermine; Starvation; Time Factors | 1973 |
Separation of biogenic amines in rat brain on a phosphorylated-cellulose column.
Topics: Amino Acids; Animals; Arginine; Biogenic Amines; Brain Chemistry; Buffers; Catecholamines; Cellulose; Chromatography, Ion Exchange; Dopamine; Female; Histamine; Histidine; Hydrogen-Ion Concentration; Indoles; Methods; Norepinephrine; Phosphorus; Putrescine; Rats; Solutions; Spectrometry, Fluorescence; Spermidine; Spermine | 1973 |
Effect of thioamide derivatives on induction of ornithine decarboxylase in rat liver.
Topics: Acetamides; Adrenal Glands; Adrenalectomy; Amides; Animals; Carboxy-Lyases; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Induction; Growth Hormone; Hypophysectomy; Liver; Male; Ornithine; Pituitary Gland; Putrescine; Rats; Spermidine; Spermine; Thiourea; Time Factors | 1973 |
Polyamines: developmental alterations in regional disposition and metabolism in rat brain.
Topics: Animals; Brain; Carbon Isotopes; Carboxy-Lyases; Cerebellum; Cerebral Cortex; DNA; Female; Hypothalamus; Male; Mesencephalon; Nerve Tissue Proteins; Pons; Rats; RNA; S-Adenosylmethionine; Spermidine; Spermine; Tritium | 1973 |
Polyamine turnover in different regions of rat brain.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Half-Life; Hypothalamus; Kinetics; Male; Mesencephalon; Pons; Putrescine; Rats; Spermidine; Spermine; Tritium | 1973 |
An IR-investigation of the helix-coil conversion of poly U.
Topics: Ethylenediamines; Magnesium; Mathematics; Models, Chemical; Nucleic Acid Conformation; Poly U; Polynucleotides; Spectrophotometry, Infrared; Spermidine; Spermine; Temperature | 1973 |
Spermine is major polyamine in sea urchins: studies of polyamines and their synthesis in developing sea urchins.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Chromatography, Paper; Electrophoresis; Methionine; Ornithine; Putrescine; Sea Urchins; Spermidine; Spermine | 1973 |
Measurement of putrescine, spermidine, and spermine in physiological fluids by use of an amino acid analyzer.
Topics: Autoanalysis; Carbon Isotopes; Carcinoma, Squamous Cell; Chromatography, Ion Exchange; Humans; Lung Neoplasms; Methods; Neoplasms; Putrescine; Spermidine; Spermine; Teratoma | 1973 |
In-vitro and in-vivo adherence of allergised lymph-node cells to BP8 ascites tumour cells, in the presence of polyamines and quarternary ammonium compounds.
Topics: Animals; Arginine; Bis-Trimethylammonium Compounds; Cell Adhesion; Freund's Adjuvant; Histamine; Immunization; Lymph Nodes; Lymphocytes; Lysine; Mice; Mice, Inbred C3H; Neoplasms, Experimental; p-Methoxy-N-methylphenethylamine; Pentolinium Tartrate; Polyamines; Quaternary Ammonium Compounds; Spermidine; Spermine | 1973 |
Inhibition of spermidine formation in rat liver and kidney by methylglyoxal bis(guanylhydrazone).
Topics: Amidines; Animals; Carbon Isotopes; Carboxy-Lyases; Glyoxal; Hydrazones; Kidney; Liver; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine; Time Factors | 1973 |
Early cyclical changes in polyamine synthesis during sea-urchin development.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Cell Division; Chromatography, DEAE-Cellulose; Embryo, Nonmammalian; Fertilization; Putrescine; Sea Urchins; Spermidine; Spermine; Time Factors | 1973 |
Polyamine synthesis and polysome patterns in the rat uterus during the oestrous cycle.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Chromatography, Thin Layer; Estrus; Female; Nucleoproteins; Ornithine; Polyamines; Polyribosomes; Pregnancy; Putrescine; Rats; Spermidine; Spermine; Ultracentrifugation; Uterus | 1973 |
Regulation of polyamine synthesis in Physarum polyciphalum during growth and differentiation.
Topics: Carbon Isotopes; Carboxy-Lyases; Cell Differentiation; Culture Media; Cycloheximide; Electrophoresis, Paper; Mitosis; Myxomycetes; Ornithine; Polyamines; Protein Denaturation; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Subcellular Fractions; Time Factors | 1973 |
Synthesis and accumulation of polyamines in rat liver regenerating after treatment with carbon tetrachloride.
Topics: Animals; Carbon Radioisotopes; Carbon Tetrachloride; Carboxy-Lyases; Chromatography, Ion Exchange; Chromatography, Paper; Female; Growth Hormone; Hepatectomy; Liver; Liver Regeneration; Ornithine; Propylamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine; Thioacetamide; Time Factors; Transferases | 1973 |
Polyamine content of AKR leukemic cells in relation to the cell cycle.
Topics: Animals; Cell Division; Cell Separation; Chromatography, Thin Layer; Female; Fluorometry; Leukemia, Experimental; Mice; Mice, Inbred AKR; Mitosis; Polyamines; Putrescine; Spermidine; Spermine; Thymidine; Thymus Gland; Tritium | 1973 |
Transfer RNA methylase activity and polyamine concentrations in regenerating rat liver.
Topics: Animals; Carbon Radioisotopes; Liver; Liver Regeneration; Polyamines; Putrescine; Rats; Spermidine; Spermine; Time Factors; tRNA Methyltransferases | 1973 |
Determination of polyamines in urine.
Topics: Ammonia; Cadaverine; Chromatography, Thin Layer; Dansyl Compounds; Evaluation Studies as Topic; Humans; Methods; Putrescine; Spectrometry, Fluorescence; Spermidine; Spermine; Urease | 1973 |
A new method for isolation of polyamines from animal tissues.
Topics: Animals; Butanols; Chromatography, Ion Exchange; Colorimetry; Electrophoresis, Paper; Methods; Polyamines; Putrescine; Rats; Spermidine; Spermine; Tissue Extracts | 1973 |
Polyamine effects on 14C-leucine transfer to microsomal protein in a rat liver cell free system during ageing.
Topics: Aging; Animals; Carbon Radioisotopes; Cell-Free System; Centrifugation; Cytoplasm; Isotope Labeling; Leucine; Microsomes, Liver; Polyamines; Protein Biosynthesis; Rats; Ribonucleases; RNA, Transfer; Spermidine; Spermine | 1973 |
Polyamine accumulation during lymphocyte transformation and its relation to the synthesis, processing, and accumulation of ribonucleic acid.
Topics: Adenosine; Animals; Carbon Radioisotopes; Cattle; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Chromatography, Thin Layer; Concanavalin A; Hydrazines; Iproniazid; Isotope Labeling; Lymph Nodes; Lymphocyte Activation; Lymphocytes; Protein Biosynthesis; Putrescine; RNA; Spermidine; Spermine; Time Factors; Tritium; Uridine | 1973 |
[Glycolytic rate limiting enzymes and polyamines in blood cell. II. Polyamines (spermine and spermidine) in blood of cancer patients (author's transl)].
Topics: Blood Cells; Humans; Neoplasms; Spermidine; Spermine | 1973 |
Stimulation of (14C)uridine incorporation into RNA by intracisternal injections of putrescine.
Topics: Animals; Brain; Carbon Isotopes; Female; Injections, Spinal; Male; Putrescine; Rats; RNA; Spermidine; Spermine; Uridine | 1973 |
Effects of methylglyoxal-bis(guanylhydrazone) on polyamine metabolism in spleens of mice with disseminated L1210 lymphoid leukemia.
Topics: Amidines; Animals; Antineoplastic Agents; Carboxy-Lyases; Glyoxal; Hydrazones; Leukemia L1210; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Ornithine; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Spleen; Time Factors | 1974 |
Occurrence of polyamines in myxoviruses.
Topics: Chromatography, Thin Layer; Dansyl Compounds; Newcastle disease virus; Orthomyxoviridae; Polyamines; Putrescine; Spermidine; Spermine | 1974 |
Ion-exchange chromatographic separation and fluorometric detection of urinary polyamines.
Topics: Buffers; Cadaverine; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Methods; Polyamines; Putrescine; Spectrometry, Fluorescence; Spermidine; Spermine | 1974 |
Studies on the function of glucocorticoid in mouse mammary epithelial cell differentiation in vitro. Stimulation of glucose 6-phosphate dehydrogenase.
Topics: Adipose Tissue; Animals; Cell Differentiation; Culture Techniques; Dose-Response Relationship, Drug; Drug Synergism; Epithelial Cells; Epithelium; Female; Glucocorticoids; Glucosephosphate Dehydrogenase; Hydrocortisone; Insulin; Magnesium; Mammary Glands, Animal; Mice; Pregnancy; Prolactin; Putrescine; Spectrophotometry, Ultraviolet; Spermidine; Spermine | 1974 |
The biological effect of polyamines on heart RNA and histone metabolism.
Topics: Animals; Carbon Radioisotopes; Cell Nucleus; Chromatography, Ion Exchange; DNA; Formates; Heart; Histones; Hypertrophy; Mitochondria, Muscle; Monoamine Oxidase; Myocardium; Rabbits; Ribosomes; RNA; Spermidine; Spermine; Subcellular Fractions; Time Factors; Tritium | 1974 |
Polyamine metabolism in tumor, spleen and liver of tumor-bearing rats.
Topics: Animals; Body Weight; Brain Neoplasms; Carbon Radioisotopes; Carboxy-Lyases; Liver; Male; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Organ Size; Polyamines; Putrescine; Rats; Spermidine; Spermine; Spleen; Time Factors; Transplantation, Homologous | 1974 |
Polyamine depletion of the MTW9 mammary tumor and subsequent elevation of spermidine in the sera of tumor-bearing rats as a biochemical marker of tumor regression.
Topics: Animals; Extracellular Space; Female; Liver; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Polyamines; Putrescine; Rats; Spermidine; Spermine; Time Factors; Transplantation, Homologous | 1974 |
Effect of isoproterenol on polyamine metabolism in mouse salivary glands.
Topics: Animals; Carbon Radioisotopes; Carboxy-Lyases; Cycloheximide; DNA; Enzyme Induction; Isoproterenol; Male; Methionine; Mice; Organ Size; Ornithine; Parotid Gland; Pilocarpine; Polyamines; Putrescine; RNA; Salivary Glands; Spermidine; Spermine; Stimulation, Chemical; Submandibular Gland; Time Factors; Uridine | 1974 |
[Significance of spermin and spermidine in chlorococcal algae].
Topics: Chlorophyta; Spermidine; Spermine | 1974 |
An automated micromethod for the quantitative analysis of di- and polyamines utilizing a sensitive high pressure liquid chromatographic procedure.
Topics: Animals; Autoanalysis; Brain; Brain Chemistry; Brain Neoplasms; Cadaverine; Carbon Radioisotopes; Chromatography, Ion Exchange; Diamines; Evaluation Studies as Topic; Kidney; Liver; Lung; Male; Methods; Microchemistry; Myocardium; Neoplasms, Experimental; Polyamines; Pressure; Putrescine; Rats; Spermidine; Spermine; Spleen | 1974 |
Polyamine biosynthesis in human fetal liver and brain.
Topics: Adult; Age Factors; Animals; Brain; Carbon Radioisotopes; Carboxy-Lyases; Female; Fetus; Humans; Liver; Ornithine; Polyamines; Pregnancy; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine | 1974 |
[Behavioral pharmacology of alkali metals. 2. Changes of brain polyamine levels in mice with aggressive behavior and effects of LiCl].
Topics: Aggression; Animals; Brain Chemistry; Catecholamines; Chlorides; Dopamine; Electric Stimulation; Humans; Lithium; Male; Mice; Norepinephrine; Polyamines; Serotonin; Social Isolation; Spermidine; Spermine | 1974 |
Polyamines in human and cow's milk.
Topics: Animals; Cadaverine; Cattle; Chromatography, Thin Layer; Dansyl Compounds; Dialysis; DNA; Europe; Female; Humans; Lactation; Methionine; Milk; Milk Proteins; Milk, Human; Polyamines; Pregnancy; Putrescine; RNA; Species Specificity; Spectrometry, Fluorescence; Spermidine; Spermine; Thailand; Time Factors | 1974 |
Polyamine metabolism in mouse liver after partial hepatectomy.
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Carboxy-Lyases; Electrophoresis; Escherichia coli; Half-Life; Hepatectomy; Kinetics; Liver; Liver Regeneration; Male; Methionine; Mice; Ornithine; Polyamines; RNA; S-Adenosylmethionine; Spermidine; Spermine; Time; Transferases | 1971 |
Urinary polyamines in cancer patients.
Topics: Brain Neoplasms; Chemistry, Clinical; Daunorubicin; Female; Hodgkin Disease; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neoplasms; Ovarian Neoplasms; Polyamines; Pregnancy; Remission, Spontaneous; Spermidine; Spermine; Teratoma | 1971 |
Separation and properties of DNA polymerases from developing rat brain.
Topics: Ammonium Sulfate; Animals; Brain; Chemical Phenomena; Chemical Precipitation; Chemistry; Chlorides; Chromatography, DEAE-Cellulose; Coliphages; Deoxyribonucleotides; Dithiothreitol; DNA; DNA Nucleotidyltransferases; DNA, Bacterial; DNA, Viral; Enzyme Activation; Escherichia coli; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Magnesium; Male; Manganese; Nucleic Acid Denaturation; Polyamines; Rats; Rats, Inbred Strains; Salmonidae; Spermatozoa; Spermidine; Spermine; Thymine Nucleotides; Thymus Gland; Tritium | 1971 |
Methionineless death in Escherichia coli.
Topics: Amino Acyl-tRNA Synthetases; Arginine; Bacterial Proteins; Bacteriological Techniques; Carbon Isotopes; Cell Survival; Culture Media; Decarboxylation; DNA, Bacterial; Escherichia coli; Filtration; Isoleucine; Leucine; Methionine; Proline; Spermidine; Spermine; Thymine; Tryptophan; Uracil | 1971 |
A correlation of seminal polyamine levels and semen analysis in the human.
Topics: Cell Movement; Electrophoresis; Fructose; Humans; Male; Polyamines; Semen; Spermatozoa; Spermidine; Spermine | 1972 |
Studies on isolated brain nuclear DNA-dependent RNA polymerase.
Topics: Animals; Cattle; Cell Nucleus; Cerebral Cortex; Chromatography, DEAE-Cellulose; Dactinomycin; DNA; Enzyme Activation; Kinetics; Manganese; Mycotoxins; Nucleic Acid Denaturation; Potassium Chloride; Rifampin; RNA; RNA Nucleotidyltransferases; Spermidine; Spermine; Templates, Genetic; Tritium; Uracil Nucleotides | 1972 |
Interrelationships between polyamines and nucleic acids. 3. Metabolic and autoradiographic studies on putrescine in mouse brain.
Topics: Animals; Autoradiography; Brain; Carbon Isotopes; Electrophoresis; Male; Mice; Nucleic Acids; Polyamines; Putrescine; Radionuclide Imaging; Spermidine; Spermine; Tritium | 1972 |
Inhibition of alkaline ribonuclease activity by polyamines.
Topics: Animals; Cell Fractionation; Cell-Free System; Hypophysectomy; Liver; Mitochondria, Liver; Pituitary Gland; Polyamines; Putrescine; Rats; Ribonucleases; RNA; Spermidine; Spermine | 1972 |
Polyamine synthesis in the regenerating rat liver: stimulation of S-adenosyl methionine decarboxylase, and spermidine and spermine synthases after partial hepatectomy.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Cycloheximide; Half-Life; Hepatectomy; Kinetics; Liver; Liver Regeneration; Ornithine; Polyamines; Propylamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine; Transferases | 1972 |
Ultrastructural changes in vitro of rat liver nucleoli in response to polyamines.
Topics: Animals; Cell Fractionation; Cell Nucleolus; Cell Nucleus; Chromatin; Liver; Male; Microscopy; Microscopy, Electron; Polyamines; Rats; Rats, Inbred Strains; RNA Nucleotidyltransferases; RNA, Ribosomal; Spermidine; Spermine | 1972 |
[Relationship between polyamines and nucleic acids. V. Stimulation of liver growth and enhancement of polyamines and nucleic acids by perfluorovaleric acid].
Topics: Animals; DNA; Liver; Male; Mice; Mice, Inbred Strains; Nucleic Acids; Organ Size; Polyamines; Putrescine; RNA; Spermidine; Spermine; Valerates | 1972 |
Effect of spermine on the uptake of amino acids in Micrococcus lysodeikticus.
Topics: Alanine; Amino Acids; Autoanalysis; Azides; Carbon Isotopes; Carrier Proteins; Cell Membrane; Dinitrophenols; Glucose; Glycine; Isoleucine; Leucine; Micrococcus; Polyamines; Protein Binding; Spermidine; Spermine; Temperature; Valine | 1972 |
Peptide synthesis by means of tert-butyloxycarbonylamino acid derivatives of poly(ethylene-co-N-hydroxymaleimide).
Topics: Alanine; Amino Acid Sequence; Anhydrides; Carboxypeptidases; Chemical Phenomena; Chemistry; Cyclohexanes; Electrophoresis, Paper; Formates; Hydrazines; Hydroxylamines; Imides; Insulin; Maleates; Maleimides; Peptides; Polyethylenes; Spermidine; Spermine; Temperature | 1972 |
Polyamines in the developing rat and in supportive tissues.
Topics: Amniotic Fluid; Animals; Carboxy-Lyases; Embryo, Mammalian; Female; Fetus; Gestational Age; Histidine; Liver; Ornithine; Polyamines; Pregnancy; Rats; Rats, Inbred Strains; RNA; S-Adenosylmethionine; Spermidine; Spermine; Uterus | 1972 |
Metabolism of polyamines in normal and scrapie-affected mouse brain and spleen.
Topics: Animals; Brain; Carbon Isotopes; Mice; Neuroglia; Polyamines; Putrescine; Scrapie; Sheep; Spermidine; Spermine; Spinal Cord; Spleen | 1972 |
Ornithine decarboxylase activity in synchronously growing Don C cells.
Topics: Animals; Anti-Bacterial Agents; Benzocycloheptenes; Carbon Isotopes; Carboxy-Lyases; Cell Line; Cells, Cultured; Cricetinae; Cycloheximide; Dactinomycin; DNA; Leucine; Lung; Ornithine; Protein Biosynthesis; Putrescine; RNA; Spermidine; Spermine; Thymidine; Tritium; Uridine | 1972 |
[Effect of spermatozoa-stablizing polycations on respiration and phosphate binding].
Topics: Animals; Histones; Male; Oxygen Consumption; Phosphates; Spermatozoa; Spermidine; Spermine; Swine | 1972 |
Effects of methotrexate and cytosine arabinoside on polyamine metabolism in a mouse L1210 leukemia.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Cytarabine; Leukemia L1210; Methotrexate; Mice; Mice, Inbred Strains; Ornithine; Polyamines; Putrescine; Spermidine; Spermine; Spleen | 1972 |
Studies on the metabolism of sym-homospermidine in sandal (Santalum albumin L.).
Topics: Arginine; Carbon Isotopes; Ornithine; Plants; Spermidine; Spermine; Tritium | 1972 |
Details for the fluorometric determination of histamine, spermidine, and spermine after sequential separation of phosphorylated cellulose.
Topics: Cellulose; Fluorometry; Histamine; Methods; Polyamines; Spermidine; Spermine | 1971 |
Mescaline-induced changes of brain cortex ribosomes. Effect of mescaline on amino acid incorporating ability of ribosomes.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cerebral Cortex; Goats; Leucine; Mescaline; Nerve Tissue Proteins; Phenylalanine; Ribosomes; RNA; Spermidine; Spermine | 1971 |
[Optimal conditions of aminoacylation of yeast tRNA Asp and tRNA Trp].
Topics: Acylation; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Aspartic Acid; Buffers; Carbon Isotopes; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Magnesium; RNA, Transfer; Solvents; Spermidine; Spermine; Temperature; Time Factors; Tryptophan; Yeast, Dried | 1971 |
Polyamine oxidase in higher plants.
Topics: Amines; Chromatography, Gas; Histocytochemistry; Oxidoreductases; Plants; Pyrroles; Spermidine; Spermine | 1971 |
Role of the 2'-hydroxyl in polynucleotide conformation: poly 2'-O-methyluridylic acid.
Topics: Adenine Nucleotides; Chemical Phenomena; Chemistry; Cytosine Nucleotides; Deamination; Deoxyribonucleotides; DNA; Drug Stability; Magnesium; Nucleic Acid Conformation; Nucleoside Diphosphate Sugars; Polynucleotides; Ribonucleotides; RNA; RNA, Ribosomal; RNA, Transfer; Sodium; Spectrophotometry; Spermidine; Spermine; Temperature; Thymine Nucleotides; Ultracentrifugation; Ultraviolet Rays; Uracil Nucleotides | 1971 |
Regulation of meningioma cell growth in vitro by polyamines.
Topics: Biopsy; Brain Neoplasms; Butylamines; Cell Count; Cells, Cultured; Culture Media; Culture Techniques; Guanidines; Humans; Meningioma; Spermidine; Spermine | 1971 |
Autoradiographic distributions of 3 H-putrescine and 3 H-uridine in a Xenopus liver cell line.
Topics: Animals; Autoradiography; Butylamines; Cell Line; Cell Nucleolus; Cell Nucleus; Cells, Cultured; Cytoplasm; Histocytochemistry; Hydroxides; Lead; Liver; Microscopy; Microscopy, Electron; Mitosis; Polyamines; Putrescine; Radioisotopes; RNA; Spermidine; Spermine; Staining and Labeling; Time Factors; Tritium; Uridine; Xenopus | 1971 |
[Clinical biochemical study of amines (spermine and spermidine). 1. Micro-quantitative analysis (3). 2. Blood levels in cancer patients (1)].
Topics: Humans; Microchemistry; Neoplasms; Polyamines; Spermidine; Spermine | 1971 |
Increased polyamine concentrations in the urine of human cancer patients.
Topics: Carcinoma; Female; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Neoplasms; Ovarian Neoplasms; Polyamines; Rectal Neoplasms; Spermidine; Spermine; Teratoma | 1971 |
Compartmentalization of spermine and spermidine in the herpes simplex virion.
Topics: Carcinoma; Cell Line; Detergents; DNA, Viral; Herpes Simplex; Herpesviridae; Humans; Ornithine; Polyamines; Protein Binding; Skin; Spermidine; Spermine; Time Factors; Tritium; Urea | 1971 |
Studies on the metabolism of , '-iminodipropionitrile in the rat.
Topics: Acetates; Amino Acids; Aminopropionitrile; Animals; Brain; Chromatography, Ion Exchange; Chromatography, Paper; Colorimetry; Electrophoresis, Paper; Ethionine; Imines; Liver; Male; Nitriles; Polyamines; Proadifen; Propionates; Rats; Spermidine; Spermine; Thiocyanates; Time Factors | 1970 |
Structural and biochemical aspects of liver cell nuclear organization in normal and scalded rats.
Topics: Animals; Burns; Calcium; Cell Nucleus; Centrifugation, Density Gradient; DNA; Edetic Acid; Egtazic Acid; Liver; Magnesium; Male; Microscopy, Electron; Nucleoproteins; Rats; RNA; Spermidine; Spermine | 1984 |
Red blood cell polyamines in mice bearing the Lewis lung carcinoma (3LL) and in patients with bronchopulmonary cancers.
Topics: Adenocarcinoma; Adult; Aged; Animals; Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Erythrocytes; Female; Humans; Lung Neoplasms; Male; Mice; Middle Aged; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
Reciprocal regulation of ornithine decarboxylase and choline kinase activities by their respective reaction products in the developing rat cerebellar cortex.
Topics: Animals; Cerebellar Cortex; Choline Kinase; Choline O-Acetyltransferase; Female; Fetus; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Phosphorylcholine; Phosphotransferases; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1984 |
Stimulation of pyruvate dehydrogenase phosphatase activity by polyamines.
Topics: Animals; Calcium; Cations, Divalent; Cattle; Enzyme Activation; Kidney; Kinetics; Magnesium; Manganese; Myocardium; Phosphoprotein Phosphatases; Polyamines; Protein Phosphatase 1; Putrescine; Pyruvate Dehydrogenase (Lipoamide)-Phosphatase; Spermidine; Spermine | 1984 |
Effect of polyamines and basic proteins on cleavage of DNA by restriction endonucleases.
Topics: Bacteriophage lambda; Bacteriophage phi X 174; Circular Dichroism; Deoxyribonuclease EcoRI; DNA Restriction Enzymes; DNA, Bacterial; DNA, Viral; Escherichia coli; Plasmids; Polyamines; Putrescine; Spermidine; Spermine; Viral Nonstructural Proteins; Viral Proteins | 1984 |
Polyamines as physiological substrates for transglutaminases.
Topics: gamma-Glutamyltransferase; Humans; Lymphocyte Activation; Lymphocytes; Male; Mitogens; Polyamines; Seminal Vesicles; Spermidine; Spermine; Structure-Activity Relationship; Substrate Specificity | 1980 |
Increased nuclear conjugated polyamines and transglutaminase during liver regeneration.
Topics: Animals; Cell Nucleus; gamma-Glutamyltransferase; Kinetics; Liver; Liver Regeneration; Male; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1981 |
Spermine and spermidine as inhibitors of gastrointestinal motor activity.
Topics: Acetylcholine; Animals; Bethanechol Compounds; Dogs; Female; Gastrointestinal Motility; Isoproterenol; Male; Phenoxybenzamine; Putrescine; Spermidine; Spermine | 1982 |
Differential conjugation of polyamines to calf nuclear and nucleolar proteins.
Topics: Animals; Cattle; Cell Nucleolus; Cell Nucleus; gamma-Glutamyltransferase; Liver; Male; Nucleoproteins; Polyamines; Putrescine; Spermidine; Spermine | 1981 |
The effect of polyamines on tyrosine hydroxylase and L-aromatic amino acid decarboxylase.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Cattle; Caudate Nucleus; Dose-Response Relationship, Drug; Kinetics; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Tyrosine 3-Monooxygenase | 1982 |
Effects of polyamines on the uptake of neurotransmitters by rat brain synaptosomes.
Topics: Animals; Brain; Dopamine; Kinetics; Male; Neurotransmitter Agents; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Structure-Activity Relationship; Synaptosomes | 1984 |
Polyamines stimulate D-glucose transport in isolated renal brush-border membrane vesicles.
Topics: Adenosine Triphosphatases; Animals; Biological Transport, Active; Ca(2+) Mg(2+)-ATPase; Calcium; Carrier Proteins; Glucose; Kidney Tubules, Proximal; Microvilli; Polyamines; Putrescine; Rabbits; Sodium; Sodium-Hydrogen Exchangers; Spermidine; Spermine | 1984 |
Polyamine-polyphosphate complexes as enzyme inhibitors.
Topics: Adenine Phosphoribosyltransferase; Diphosphoglyceric Acids; Hypoxanthine Phosphoribosyltransferase; Kinetics; Magnesium; Orotate Phosphoribosyltransferase; Pentosephosphates; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Phosphotransferases; Polyamines; Putrescine; Ribose-Phosphate Pyrophosphokinase; Spermidine; Spermine | 1980 |
Relationships between polyamine metabolism and RNA synthesis in post-ischemic liver cell repair.
Topics: Adenosylmethionine Decarboxylase; Animals; Hypophysectomy; Ischemia; Liver; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; RNA; Spermidine; Spermine | 1980 |
Determination of putrescine, spermine and spermidine in human tissues of prostate and kidney.
Topics: Adenocarcinoma; Adult; Humans; Kidney; Kidney Neoplasms; Male; Polyamines; Prostate; Prostatic Hyperplasia; Putrescine; Spermidine; Spermine | 1980 |
Relationship between polyamine accumulation and RNA biosynthesis and content during the cell cycle.
Topics: Animals; Cell Cycle; Cells, Cultured; Chick Embryo; Cricetinae; Fibroblasts; HeLa Cells; Humans; Polyamines; Putrescine; RNA; Spermidine; Spermine | 1981 |
Paradoxical effect of perchlorate on thyroidal weight, glucose 6-phosphate dehydrogenase and polyamines in methylthiouracil-treated rats.
Topics: Animals; Antithyroid Agents; DNA; Glucosephosphate Dehydrogenase; Male; Methylthiouracil; Organ Size; Ornithine Decarboxylase; Perchlorates; Polyamines; Putrescine; Rats; RNA; Sodium Compounds; Spermidine; Spermine; Thyroid Gland; Thyrotropin | 1981 |
Developmental changes of the GABA and polyamine systems in isolated neurons in cell culture.
Topics: Aging; Amino Acids; Animals; Cerebral Cortex; Chick Embryo; DNA; gamma-Aminobutyric Acid; Putrescine; RNA; Spermidine; Spermine | 1981 |
Formation of acetylpolyamines in the liver of fasting animals.
Topics: Acetyltransferases; Animals; Body Weight; DNA; Fasting; Liver; Male; Mice; Organ Size; Polyamines; Rats; Rats, Inbred Strains; RNA; Spermidine; Spermine | 1981 |
[RNA transport from isolated nuclei of cultured Djungarian hamster cells].
Topics: Animals; Biological Transport; Cell Line; Cell Nucleus; Cell Transformation, Viral; Cricetinae; Dithiothreitol; Kinetics; RNA; Simian virus 40; Spermidine; Spermine | 1982 |
Metabolism and axonal transport of polyamines in a single identified neuron of Aplysia californica.
Topics: Animals; Aplysia; Axonal Transport; Kinetics; Neurons; Putrescine; Radioisotope Dilution Technique; Spermidine; Spermine; Tritium | 1982 |
Blood polyamine levels in psoriasis patients undergoing PUVA treatment.
Topics: Adult; Humans; Male; Middle Aged; Photochemotherapy; Psoriasis; PUVA Therapy; Spermidine; Spermine | 1981 |
Association of spermine and 4S RNA during axonal transport in regenerating optic nerves of goldfish.
Topics: Animals; Axonal Transport; Electrophoresis, Polyacrylamide Gel; Goldfish; Molecular Weight; Nerve Regeneration; Optic Nerve; RNA; Spermidine; Spermine; Superior Colliculi; Visual Pathways | 1982 |
Methylglyoxal BIS (guanylhydrazone) and alpha-difluoromethylornithine-induced polyamine deprivation in psoriatic lesions.
Topics: Carboxy-Lyases; Dose-Response Relationship, Drug; Eflornithine; Guanidines; Humans; Injections, Intradermal; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Psoriasis; Putrescine; Skin; Spermidine; Spermine | 1982 |
Interferon induction of polyamine-dependent protein kinase activity in Ehrlich ascites tumor cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Nucleus; Chromatography, Affinity; Cytoplasm; Interferons; Mice; Molecular Weight; Poly I-C; Polyamines; Protein Kinases; Spermidine; Spermine | 1982 |
Macromolecular synthesis and stability in growth-arrested BALB/c-3T3 cells.
Topics: Animals; Cell Cycle; Cells, Cultured; Dactinomycin; Interphase; Mice; Mitoguazone; Polyamines; RNA; Spermidine; Spermine; Time Factors | 1982 |
The role of polyamines in animal cell physiology.
Topics: Animals; Cell Cycle; Cell Division; Cell Membrane; Chick Embryo; DNA; Enzyme Induction; Mice; Ornithine Decarboxylase; Polyamines; Protein Biosynthesis; Rats; RNA; Spermidine; Spermine | 1982 |
[Therapy of prostate carcinoma with polyamine synthesis inhibitors. I. Physiological and pathophysiological principles].
Topics: Antineoplastic Agents; Humans; Male; Polyamines; Prostatic Hyperplasia; Prostatic Neoplasms; Putrescine; Spermidine; Spermine | 1982 |
The interactions between nucleic acids and polyamines. II. Protonation constants and 13C-NMR chemical shift assignments of spermidine, spermine, and homologs.
Topics: Chemical Phenomena; Chemistry; DNA; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Polyamines; RNA; Spermidine; Spermine; Structure-Activity Relationship | 1983 |
Interaction between polyamines and nucleic acids or phospholipids.
Topics: Animals; DNA; Kinetics; Magnesium; Phospholipids; Polyamines; Polyribonucleotides; Ribosomes; RNA; Species Specificity; Spermidine; Spermine; Structure-Activity Relationship | 1982 |
[Determination of polyamines in the urine].
Topics: Humans; Hydrolysis; Polyamines; Putrescine; Spectrometry, Fluorescence; Spermidine; Spermine | 1983 |
Efficacy of combinations of difluoromethylornithine and bleomycin in a mouse model of central nervous system African trypanosomiasis.
Topics: Animals; Bleomycin; Central Nervous System Diseases; Disease Models, Animal; Drug Therapy, Combination; Eflornithine; Female; Male; Mice; Ornithine; Spermidine; Spermine; Trypanocidal Agents; Trypanosomiasis, African | 1983 |
Smooth muscle cell hypertrophy and hyperplasia in the rat detrusor after short-time infravesical outflow obstruction.
Topics: Animals; DNA; Female; Hyperplasia; Hypertrophy; Muscle, Smooth; Ornithine Decarboxylase; Rats; Rats, Inbred Strains; RNA; Spermidine; Spermine; Urethral Obstruction; Urinary Bladder | 1984 |
Cardiovascular and respiratory effects of spermidine and spermine: an experimental study.
Topics: Animals; Blood Pressure; Dogs; Heart Rate; Hemodynamics; Histamine Release; Male; Neurotransmitter Agents; Pressoreceptors; Respiratory System; Spermidine; Spermine | 1984 |
Effect of polyamine antimetabolites on cultured human keratinocytes from normal and uninvolved psoriatic skin.
Topics: Antimetabolites; Cell Division; Cells, Cultured; DNA; Eflornithine; Guanidines; Humans; Keratins; Mitoguazone; Ornithine; Protein Biosynthesis; Psoriasis; Putrescine; Skin; Spermidine; Spermine | 1984 |
Assays for regulatory properties of polyamine-dependent protein kinase.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Cell Nucleus; Cytosol; Enzyme Induction; Indicators and Reagents; Interferons; Mice; Phosphorus Radioisotopes; Phosphorylation; Physarum; Protein Kinases; Spermidine; Spermine | 1984 |
Hyperplasia and hypertrophia in the denervated and distended rat urinary bladder.
Topics: Animals; Cadaverine; Denervation; DNA; Hyperplasia; Hypertrophy; Male; Parasympathetic Nervous System; Putrescine; Rats; Rats, Inbred Strains; RNA; Spermidine; Spermine; Urinary Bladder | 1984 |
Action of polyamines on ribonucleic acid and protein synthesis during ontogeny of human fetal liver.
Topics: Fetus; Gestational Age; Humans; In Vitro Techniques; Liver; Polyamines; Protein Biosynthesis; Putrescine; RNA; Spermidine; Spermine | 1984 |
Decreased polyamine content of concanavalin a stimulated lymphocytes in Down's syndrome subjects.
Topics: Adolescent; Adult; Cells, Cultured; Concanavalin A; Down Syndrome; Humans; Lymphocyte Activation; Lymphocytes; Spermidine; Spermine; Time Factors | 1982 |
Compartmentation of spermidine in Neurospora crassa.
Topics: Carbon Radioisotopes; Kinetics; Neurospora; Neurospora crassa; Ornithine; Putrescine; Spermidine; Spermine; Subcellular Fractions | 1983 |
Dynamics of DNA condensation.
Topics: Bacteriophage lambda; Chemical Phenomena; Chemistry; DNA, Viral; Kinetics; Light; Scattering, Radiation; Spermidine; Spermine; T-Phages | 1984 |
The purification and properties of chicken liver RNase: An enzyme which is useful in distinguishing between cytidylic and uridylic acid residues.
Topics: Animals; Cations; Chickens; Cytidine Monophosphate; Endonucleases; Kinetics; Liver; Putrescine; Ribonucleases; Spermidine; Spermine; Substrate Specificity; Uridine Monophosphate | 1980 |
Stimulation of glucose-6-phosphatase by polyamines is a membrane-mediated event.
Topics: Animals; Enzyme Activation; Glucose-6-Phosphatase; Intracellular Membranes; Kinetics; Male; Microsomes, Liver; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1980 |
Polyamines in encephalomyocarditis virus.
Topics: Cadaverine; Cell Line; Encephalomyocarditis virus; Genes, Viral; Polyamines; Putrescine; Spermidine; Spermine | 1980 |
Stimulation of muscle glycogen synthase phosphatase by polyamines.
Topics: Animals; Diaphragm; Enzyme Activation; Glycogen-Synthase-D Phosphatase; Insulin; Kinetics; Male; Manganese; Muscles; Phosphoprotein Phosphatases; Polyamines; Putrescine; Rabbits; Rats; Spermidine; Spermine | 1980 |
Polyamine metabolism in MRC-5 cells infected with human cytomegalovirus.
Topics: Biological Transport; Cell Line; Cytomegalovirus; DNA, Viral; Humans; Kinetics; Mitoguazone; Putrescine; Spermidine; Spermine; Time Factors | 1980 |
Effect of polyamines on ADP-ribosylation by chick-embryo-liver nuclei.
Topics: Animals; Cell Nucleus; Chick Embryo; Deoxyribonucleases; DNA; Kinetics; Liver; Magnesium; Micrococcal Nuclease; NAD+ Nucleosidase; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Polyamines; Putrescine; Spermidine; Spermine | 1980 |
The effect of polyamines on herpes simplex virus type 1 DNA polymerase purified from infected baby hamster kidney cells (BHK-21/C13).
Topics: Animals; Cell Line; Cricetinae; DNA-Directed DNA Polymerase; DNA, Viral; Dose-Response Relationship, Drug; Kidney; Mesocricetus; Putrescine; Simplexvirus; Spermidine; Spermine; Viral Proteins | 1980 |
Formation of acetylpolyamines and putrescine from spermidine by normal and transformed chick embryo fibroblasts.
Topics: Acetylation; Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Polyamines; Putrescine; Spermidine; Spermine | 1981 |
CSF polyamines. Potential as brain tumor markers.
Topics: Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Glioblastoma; Humans; Medulloblastoma; Polyamines; Putrescine; Spermidine; Spermine | 1981 |
Polyamines stimulate DNA-directed DNA synthesis catalyzed by mammalian type C retroviral DNA polymerases.
Topics: Cadaverine; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Kinetics; Magnesium; Polyamines; Putrescine; Rauscher Virus; Retroviridae; Species Specificity; Spermidine; Spermine; Templates, Genetic; Virus Replication | 1981 |
Effect of polyamines on purified poly(ADP-ribose) synthetase from rat liver nuclei.
Topics: Animals; Cell Nucleus; DNA; Dose-Response Relationship, Drug; Histones; Kinetics; Liver; Magnesium; NAD; NAD+ Nucleosidase; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1981 |
Effects of dexamethasone and dibutyryl cyclic AMP on polyamine synthesizing enzymes in mouse lymphoma cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Bucladesine; Carboxy-Lyases; Cell Line; Dexamethasone; Interphase; Lymphoma; Mice; Ornithine Decarboxylase; Protein Kinases; Putrescine; Spermidine; Spermine | 1981 |
Characterization of DNA kinase from calf thymus.
Topics: Animals; Cattle; Hydrogen-Ion Concentration; Kinetics; Magnesium; Magnesium Chloride; Phosphotransferases; Polynucleotide 5'-Hydroxyl-Kinase; Putrescine; Spermidine; Spermine; Substrate Specificity; Thymus Gland | 1981 |
Effects of polyamines on calcium-dependent rat brain phosphatidylinositol-phosphodiesterase.
Topics: Animals; Brain; Cadaverine; Calcium; Enzyme Activation; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1981 |
The effects of polyamines on the cyclic AMP efflux and metabolism in E. coli B cells.
Topics: Adenylyl Cyclases; Cell Membrane; Cyclic AMP; Escherichia coli; Kinetics; Phosphoric Diester Hydrolases; Putrescine; Spermidine; Spermine | 1981 |
Mediation of polyamine-induced decrease of cyclic AMP content by cyclic AMP-phosphodiesterase in chick heart cell cultures.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cells, Cultured; Chick Embryo; Cyclic AMP; Heart; Kinetics; Myocardium; Polyamines; Putrescine; Spermidine; Spermine | 1981 |
Temperature-dependent and transformation-associated changes in polyamine metabolism in normal and Rous sarcoma virus-infected chick embryo fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Eflornithine; Fibroblasts; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine; Spermine; Temperature | 1981 |
Excretion of polyamines from baby hamster kidney cells (BHK-21/C13: effect of infection with Herpes Simplex Virus Type 1.
Topics: Animals; Cell Line; Cricetinae; Kidney; Polyamines; Putrescine; Simplexvirus; Spermidine; Spermine | 1981 |
Levels of polyamines and nucleic acids in human breast carcinoma.
Topics: Adult; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; DNA, Neoplasm; Female; Humans; Middle Aged; Polyamines; Putrescine; RNA, Neoplasm; Spermidine; Spermine | 1981 |
Role of polyamines in the proliferation and steroidogenic activities of bovine adrenocortical cells in culture.
Topics: Adrenal Cortex; Animals; Carboxy-Lyases; Cattle; Cell Division; Cells, Cultured; Cosyntropin; Cyclic AMP; Eflornithine; Hydrocortisone; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine | 1981 |
Poly(adenylate) polymerase activity of rat brain.
Topics: Animals; Brain; Cell Nucleus; Cyclic AMP; Cyclic GMP; Female; Kinetics; Male; Nucleotidyltransferases; Polynucleotide Adenylyltransferase; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1982 |
Hydrolyzing activities on cAMP in E. coli B cells incubated in the presence of polyamines.
Topics: Cyclic AMP; Escherichia coli; Hydrolysis; Kinetics; Phosphoric Diester Hydrolases; Putrescine; Spermidine; Spermine | 1982 |
Purification and characterization of a wheat germ protein kinase.
Topics: Cyclic AMP; Heparin; Kinetics; Magnesium; Molecular Weight; Plants; Protein Kinases; Putrescine; Spermidine; Spermine; Substrate Specificity; Triticum | 1982 |
Changes of ornithine decarboxylase activity and polyamine content upon differentiation of mouse NB-15 neuroblastoma cells.
Topics: Acetylcholinesterase; Animals; Carboxy-Lyases; Cell Differentiation; Cell Line; Cyclic AMP; Mice; Neuroblastoma; Neurons; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1982 |
Inhibitors of polyamine biosynthesis block human cytomegalovirus replication.
Topics: Antiviral Agents; Cells, Cultured; Cytomegalovirus; Eflornithine; Guanidines; Humans; Mitoguazone; Ornithine; Polyamines; Spermidine; Spermine; Virus Replication | 1982 |
Heparin inhibition and polyamine stimulation of a glycogen synthase kinase (PC0.7) from rabbit skeletal muscle.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Glycogen Synthase Kinases; Heparin; Histones; Magnesium; Muscles; Polyamines; Protein Kinase Inhibitors; Putrescine; Rabbits; Spermidine; Spermine | 1982 |
Effect of 5'-deoxy-5'-isobutylthioadenosine on putrescine uptake and polyamine biosynthesis by chick embryo fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Deoxyadenosines; Fibroblasts; Putrescine; Spermidine; Spermine; Thionucleosides | 1982 |
Ornithine decarboxylase and polyamine levels are reduced in CHO cells deficient in cAMP-dependent protein kinase.
Topics: Animals; Bucladesine; Carboxy-Lyases; Cell Line; Chorionic Gonadotropin; Cricetinae; Cricetulus; Cyclic AMP; Female; Kinetics; Mutation; Ornithine Decarboxylase; Ovary; Polyamines; Protein Kinases; Putrescine; Spermidine; Spermine | 1982 |
Regulation of polyamine content in cultured fibroblasts.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Cell Transformation, Viral; Cells, Cultured; Fibroblasts; Kinetics; Mice; Polyamines; Putrescine; Simian virus 40; Spermidine; Spermine | 1982 |
Inhibitor effect of polyamines on reduction of cytochrome C by superoxide anion.
Topics: Cytochrome c Group; Oxidation-Reduction; Oxygen; Polyamines; Putrescine; Spectrophotometry; Spermidine; Spermine; Superoxides | 1980 |
Effects of S-adenosyl-1,8-diamino-3-thiooctane on polyamine metabolism.
Topics: Adenosine; Animals; Cell Transformation, Viral; Cells, Cultured; Fibroblasts; Liver Neoplasms, Experimental; Mice; Putrescine; Rats; Simian virus 40; Spermidine; Spermidine Synthase; Spermine | 1982 |
Polyamine-induced hydrolysis of apurinic sites in DNA and nucleosomes.
Topics: Animals; Apurinic Acid; Cadaverine; Cations, Divalent; Cell Line; DNA; Endonucleases; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mice; Nucleosomes; Osmolar Concentration; Plasmacytoma; Polyamines; Polynucleotides; Putrescine; Spermidine; Spermine; Structure-Activity Relationship | 1982 |
Polyamine-like effects of cobalt (III) hexaammine on various cyclic nucleotide-independent protein phosphokinase reactions.
Topics: Animals; Cattle; Chromatin; Chromosomal Proteins, Non-Histone; Cobalt; Cyclic AMP; Electrochemistry; Enzyme Activation; Male; Protein Kinases; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1983 |
Urinary polyamines for evaluating the course of disease for patients with small cell carcinoma of the lung.
Topics: Carcinoma, Small Cell; Creatinine; Humans; Lung Neoplasms; Neoplasm Metastasis; Polyamines; Putrescine; Regression Analysis; Spermidine; Spermine; Time Factors | 1983 |
Regulation of the activation of chloroplast fructose-1,6-bisphosphatase: inhibition by spermidine and spermine.
Topics: Calcium; Chloroplasts; Enzyme Activation; Fructose-Bisphosphatase; Spermidine; Spermine | 1983 |
Effects of polyamines on cyclic AMP-mediated stimulation of amino acid transport in isolated rat hepatocytes.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Bucladesine; Cadaverine; Cyclic AMP; Glucagon; Kinetics; Leucine; Liver; Male; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1983 |
D,L-alpha-difluoromethylornithine inhibits human cytomegalovirus replication.
Topics: Cells, Cultured; Cytomegalovirus; DNA, Viral; Eflornithine; Humans; Male; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Simplexvirus; Spermidine; Spermine; Viral Proteins; Virion; Virus Replication | 1984 |
Ethylglyoxal bis(guanylhydrazone) as an inhibitor of polyamine biosynthesis in L1210 leukemia cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Guanidines; Leukemia L1210; Microscopy, Electron; Mitochondria; Mitoguazone; Polyamines; Receptors, Cell Surface; Spermidine; Spermine | 1984 |
Radiochemical determination of polyamines in poliovirus and human rhinovirus 14.
Topics: Eflornithine; HeLa Cells; Humans; Kinetics; Ornithine; Ornithine Decarboxylase Inhibitors; Poliovirus; Putrescine; Rhinovirus; Spermidine; Spermine | 1984 |
Activation of ADP-ribosyltransferase in polyamine-depleted mammalian cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cells, Cultured; Centrifugation, Density Gradient; Chromatography; Cricetinae; DNA; Enzyme Activation; Fibroblasts; Kidney; Mitoguazone; Nucleotidyltransferases; Ornithine; Poly(ADP-ribose) Polymerases; Spermidine; Spermine | 1984 |
Spermine-enhanced protein phosphorylation in human placenta.
Topics: Adenosine Triphosphate; Cyclic AMP; Dose-Response Relationship, Drug; Female; Humans; Molecular Weight; Phosphoproteins; Phosphorylation; Placenta; Polylysine; Pregnancy; Putrescine; Spermidine; Spermine | 1984 |
Preparation of polyamine antibody and its use in enzyme immunoassay of spermine and spermidine with beta-D-galactosidase as a label.
Topics: Animals; Antibody Formation; Antibody Specificity; Galactosidases; Humans; Immunoenzyme Techniques; Neoplasms; Rabbits; Spermidine; Spermine | 1983 |
Isolation and characterization of a tRNA(guanine-7-)-methyltransferase from Salmonella typhimurium.
Topics: Chromatography, Gel; Kinetics; Magnesium; Magnesium Chloride; Molecular Weight; RNA, Transfer; S-Adenosylmethionine; Salmonella typhimurium; Spermidine; Spermine; tRNA Methyltransferases | 1983 |
A polyamine-sensitive mutant of Aspergillus nidulans.
Topics: Aspergillus nidulans; Mutation; Nitrogen; Polyamines; Putrescine; Spermidine; Spermine | 1983 |
Effect of polyamines on palmitoyl-coenzyme A-caused inhibition of glucose-6-phosphate dehydrogenase from baker's yeast.
Topics: Acyl Coenzyme A; Adrenal Glands; Animals; Cattle; Glucosephosphate Dehydrogenase; Kinetics; Palmitoyl Coenzyme A; Polyamines; Putrescine; Saccharomyces cerevisiae; Spermidine; Spermine | 1983 |
Polyamine oxidase-mediated intraerythrocytic killing of Plasmodium falciparum: evidence against the role of reactive oxygen metabolites.
Topics: Animals; Cattle; Erythrocytes; Kinetics; Malaria; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Plasmodium falciparum; Polyamine Oxidase; Spermidine; Spermine | 1984 |
Spermidine and spermine stimulate the activity of T4-DNA ligase.
Topics: DNA Ligases; Enzyme Activation; Escherichia coli; Kinetics; Polyamines; Polynucleotide Ligases; Spermidine; Spermine; Structure-Activity Relationship; T-Phages | 1983 |
Polyamine oxidase mediates intra-erythrocytic death of Plasmodium falciparum.
Topics: Animals; Erythrocytes; Methionine; Oxidoreductases Acting on CH-NH Group Donors; Plasmodium falciparum; Polyamine Oxidase; Spermidine; Spermine | 1983 |
Analysis of the coliphage T5 DNA ejection process with free and liposome-associated TonA protein.
Topics: Adsorption; Bacterial Outer Membrane Proteins; DNA, Viral; Escherichia coli; Liposomes; Magnesium; Membrane Proteins; Putrescine; Receptors, Virus; Spermidine; Spermine; T-Phages; Temperature | 1984 |
Specificity of polyamine requirements for the replication and maintenance of different double-stranded RNA plasmids in Saccharomyces cerevisiae.
Topics: Genotype; Kinetics; Mutation; Plasmids; RNA, Double-Stranded; Saccharomyces cerevisiae; Species Specificity; Spermidine; Spermine; Transcription, Genetic | 1984 |
[Polyamines as biochemical markers of malignant tumors and the efficacy of chemotherapy].
Topics: Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Humans; Middle Aged; Neoplasms; Polyamines; Putrescine; Spermidine; Spermine | 1983 |
Inhibition of ornithine decarboxylase induces embryonal carcinoma cell differentiation.
Topics: Animals; Carboxy-Lyases; Cell Differentiation; Cell Line; Eflornithine; Mice; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine; Teratoma | 1983 |
GTP-insensitive ornithine decarboxylase in acetobacteria able to synthesize spermine.
Topics: Acetobacter; Bacillus subtilis; Carboxy-Lyases; Escherichia coli; Guanosine Triphosphate; Kinetics; Ornithine Decarboxylase; Putrescine; Species Specificity; Spermidine; Spermine | 1983 |
Determination of free and total polyamines in human serum and urine by ion-pairing high-performance liquid chromatography using a radial compression module. Application to blood polyamine determination in cancer patients treated or not treated with an orn
Topics: Aged; Cadaverine; Chromatography, High Pressure Liquid; Eflornithine; Female; Fluorescence; Humans; Male; Middle Aged; Neoplasms; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1983 |
Kinetic properties of spermine synthase from bovine brain.
Topics: Adenosine; Animals; Brain; Cattle; Deoxyadenosines; Kinetics; Placenta; Purine-Nucleoside Phosphorylase; Serum Albumin, Bovine; Spermidine; Spermine; Spermine Synthase; Thionucleosides; Transferases | 1983 |
Role of polyamines in differentiation of 3T3-L1 fibroblasts into adipocytes.
Topics: Adipose Tissue; Animals; Cell Differentiation; Cells, Cultured; Eflornithine; Fibroblasts; Mice; Ornithine; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
Effects of polyamine depletion on proliferation and differentiation of murine erythroleukemia cells.
Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Diazepam; Dimethyl Sulfoxide; Eflornithine; Kinetics; Leukemia, Experimental; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
Inhibition of platelet aggregation and endogenous lectin activity by oligoamines.
Topics: Amino Acids; Animals; Cattle; Dose-Response Relationship, Drug; Hemagglutination Tests; Histidine; Humans; Lectins; Lysine; Ornithine; Platelet Aggregation; Putrescine; Serotonin; Spermidine; Spermine; Thrombin | 1984 |
Decreased protein-synthetic activity is an early consequence of spermidine depletion in rat hepatoma tissue-culture cells.
Topics: Animals; Cell Division; Cells, Cultured; Centrifugation, Density Gradient; Cycloheximide; Eflornithine; Liver Neoplasms, Experimental; Macromolecular Substances; Neoplasm Proteins; Ornithine; Polyribosomes; Putrescine; Rats; Spermidine; Spermine | 1984 |
Involvement of spermidine in proliferation and differentiation of human promyelocytic leukemia cells.
Topics: Acetamides; Antineoplastic Agents; Cell Line; Cell Transformation, Neoplastic; DNA; Eflornithine; Humans; Leukemia, Myeloid, Acute; Ornithine; Putrescine; Spermidine; Spermine | 1984 |
Enhancement of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced cytotoxicity and DNA damage by alpha-difluoromethylornithine in L1210 leukemia cells.
Topics: Animals; Carmustine; Cell Survival; DNA, Neoplasm; Drug Synergism; Eflornithine; Kinetics; Leukemia L1210; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
Polyamines as mediators of estrogen action on the growth of experimental breast cancer in rats.
Topics: Animals; Cell Aggregation; Eflornithine; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1984 |
Lack of inhibition of diamine oxidase during hydralazine therapy.
Topics: Amine Oxidase (Copper-Containing); Cadaverine; Humans; Hydralazine; Hypertension; Male; Putrescine; Spermidine; Spermine | 1984 |
Polyamine biosynthetic enzymes as targets in cancer chemotherapy.
Topics: Adenine Nucleotides; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA; Eflornithine; Enzyme Inhibitors; Methionine; Mice; Ornithine; Putrescine; Spermidine; Spermine; Teratoma | 1984 |
Cellular proliferation and hypusine synthesis.
Topics: Animals; Cell Division; Cell Line; Cricetinae; Cricetulus; Culture Media; DNA; Female; Fibroblasts; Humans; Kinetics; Lysine; Ovary; Polyamines; Protein Biosynthesis; Putrescine; Spermidine; Spermine | 1984 |
Polyamines in brain and heart of the neonatal rat: effects of inhibitors of ornithine decarboxylase and spermidine synthase.
Topics: Animals; Animals, Newborn; Brain; Cyclohexylamines; Dose-Response Relationship, Drug; Eflornithine; Female; Heart; Male; Myocardium; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermidine Synthase; Spermine; Transferases | 1984 |
Polyamines and the development of monocrotaline-induced pulmonary hypertension.
Topics: Adenosylmethionine Decarboxylase; Animals; Blood Pressure; Eflornithine; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Kinetics; Lung; Male; Monocrotaline; Ornithine; Ornithine Decarboxylase Inhibitors; Plants, Toxic; Polyamines; Putrescine; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Senecio; Spermidine; Spermine | 1984 |
Treatment with alpha-difluoromethylornithine plus a spermidine analog leads to spermine depletion and growth inhibition in cultured L1210 leukemia cells.
Topics: Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Eflornithine; Leukemia L1210; Mice; Ornithine; Spermidine; Spermine | 1984 |
Polyamines and pancreatic growth induced by caerulein.
Topics: Animals; Ceruletide; DNA; Eflornithine; Male; Organ Size; Ornithine; Pancreas; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1984 |
[Dynamics of the elevation of hepatic polyamines after partial hepatectomy in the rat].
Topics: Animals; Cell Division; Kinetics; Liver; Liver Regeneration; Male; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1980 |
Synthetic enterobactin analogues. Carboxamido-2,3-dihydroxyterephthalate conjugates of spermine and spermidine.
Topics: Animals; Chelating Agents; Enterobactin; Female; Humans; Iron; Mice; Phthalic Acids; Plutonium; Serine; Spermidine; Spermine | 1981 |
Cation-induced toroidal condensation of DNA studies with Co3+(NH3)6.
Topics: Bacteriophage lambda; Cobalt; DNA, Viral; Kinetics; Light; Microscopy, Electron; Nucleic Acid Conformation; Scattering, Radiation; Spermidine; Spermine; T-Phages; Temperature | 1980 |
Metabolic sequestration of putrescine in Neurospora crassa.
Topics: Carbon Radioisotopes; Kinetics; Neurospora; Neurospora crassa; Ornithine; Putrescine; Radioisotope Dilution Technique; Spermidine; Spermine | 1982 |
In vitro studies on the entry of polyamines into normal red blood cells.
Topics: Biological Transport; Energy Metabolism; Erythrocytes; Female; Humans; In Vitro Techniques; Kinetics; Male; Microscopy, Electron, Scanning; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
The effects of alkali-metal chlorides and of spermidine and spermine on the swelling pressures of DNA gels in the ultracentrifuge.
Topics: Animals; Cattle; DNA; Gels; Nucleic Acid Conformation; Sodium Chloride; Spermidine; Spermine; Thymus Gland; Ultracentrifugation | 1984 |
Progressive increase in polyamine levels in 9L cells in vitro during the cell cycle: comparison between cells isolated by centrifugal elutriation and cells grown in synchrony.
Topics: Animals; Brain Neoplasms; Cell Cycle; Cell Line; Centrifugation; Kinetics; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1984 |
Effects of (2R, 5R)-6-heptyne-2,5-diamine, a potent inhibitor of L-ornithine decarboxylase, on rat hepatoma cells cultured in vitro.
Topics: Adenosylmethionine Decarboxylase; Alkynes; Animals; Cell Division; Cell Survival; Cells, Cultured; Diamines; Liver Neoplasms, Experimental; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Spermidine; Spermine | 1984 |
Stimulation of RNA polymerases from mouse spleen by polyamines and its modification by ammonium sulfate.
Topics: Ammonium Sulfate; Animals; DNA-Directed RNA Polymerases; Kinetics; Mice; Polyamines; Putrescine; RNA Polymerase I; RNA Polymerase II; RNA Polymerase III; Spermidine; Spermine; Spleen | 1984 |
Representative applications of heparin-sepharose in the removal of polyamines from biological materials.
Topics: Animals; Cattle; DNA; Female; Male; Membranes; Methods; Mitochondria, Heart; Polyamines; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Sepharose; Spermidine; Spermine | 1984 |
Polyamine-stimulated phosphorylation of proteins from corn (Zea mays L.) coleoptiles.
Topics: Calcium Chloride; Magnesium; Magnesium Chloride; Molecular Weight; Phosphorylation; Plant Proteins; Plants; Polyamines; Putrescine; Spermidine; Spermine; Zea mays | 1984 |
Regulation of protein phosphorylation by polyamines in hepatocytes.
Topics: Animals; Cell-Free System; Dose-Response Relationship, Drug; Enzyme Reactivators; Kinetics; Liver; Male; Phosphoproteins; Phosphorylation; Polyamines; Pyruvate Kinase; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1984 |
Polyamines in colorectal cancer.
Topics: Aged; Colonic Neoplasms; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Polyamines; Putrescine; Rectal Neoplasms; Spermidine; Spermine | 1984 |
[Studies on a biochemical marker of malignant bladder tumors. Polyamine concentrations in tissues of bladder cancer].
Topics: Carcinoma, Transitional Cell; Female; Humans; Male; Middle Aged; Polyamines; Putrescine; Spermidine; Spermine; Urinary Bladder Neoplasms | 1984 |
Effect of 5'-methylthioadenosine on induction of murine erythroleukemia cell differentiation.
Topics: Adenosine; Animals; Cell Differentiation; Cell Division; Cell Line; Deoxyadenosines; Dimethyl Sulfoxide; Kinetics; Leukemia, Experimental; Mice; Putrescine; Spermidine; Spermine; Thionucleosides | 1984 |
Reversible inhibition of bacterial growth after specific inhibition of spermidine synthase by dicyclohexylamine.
Topics: Bacteria; Cyclohexylamines; Putrescine; Spermidine; Spermidine Synthase; Spermine; Transferases | 1984 |
Analysis of dansyl derivatives of di- and polyamines in mouse brain, human serum and duodenal biopsy specimens by high-performance liquid chromatography on a standard reversed-phase column.
Topics: Animals; Brain Chemistry; Child, Preschool; Chromatography, High Pressure Liquid; Dansyl Compounds; Duodenum; Humans; Mice; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
Syntheses of 15N-enriched polyamines.
Topics: Polyamines; Spermidine; Spermine | 1984 |
Acetylation of polyamines in chicken brain and retina.
Topics: Acetylation; Acetyltransferases; Aging; Alkaline Phosphatase; Animals; Brain; Chick Embryo; Chickens; Protein Kinases; Putrescine; Retina; Spermidine; Spermine; Tissue Distribution | 1984 |
Stimulation of RNA polymerases I and II from mouse L1210 leukemia and Ehrlich ascites carcinoma cells by spermine and spermidine and its modification by ammonium sulfate.
Topics: Ammonium Sulfate; Animals; Carcinoma, Ehrlich Tumor; Cell Nucleus; Drug Interactions; Kinetics; Leukemia L1210; Liver Neoplasms, Experimental; Mice; Mice, Inbred Strains; RNA Polymerase I; RNA Polymerase II; Spermidine; Spermine | 1984 |
Potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity in 9L rat brain tumor cells by methylglyoxal-bis(guanylhydrazone), an inhibitor of S-adenosyl-L-methionine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Animals; Brain Neoplasms; Carboxy-Lyases; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Guanidines; Mitoguazone; Putrescine; Rats; Spermidine; Spermine | 1984 |
Enhancing effect of polyamines on yield of film sarcoma.
Topics: Animals; Clupeine; Cocarcinogenesis; Collodion; Female; Fibrosarcoma; Filtration; Male; Mice; Mice, Inbred BALB C; Peptides; Polyamines; Protamines; Putrescine; Spermidine; Spermine; Time Factors | 1984 |
A pioneer synthesis of conjugates of a thymic peptide hormone and polyamines.
Topics: Animals; Cell Division; Chemical Phenomena; Chemistry; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Peptides; Spermidine; Spermine; Thymic Factor, Circulating; Thymus Hormones | 1984 |
Periimplantation-like growth and development of mouse blastocysts in medium containing horse serum.
Topics: Animals; Blastocyst; Blood; Cattle; Culture Media; Embryo Implantation; Female; Fetal Blood; Horses; Mice; Mice, Inbred ICR; Mitoguazone; Ornithine; Polyamines; Spermidine; Spermine | 1984 |
Effect of spermine on interaction of DNA polymerase alpha from the loach (Misgurnus fossilis) eggs with DNA.
Topics: Animals; Cattle; DNA; DNA Polymerase II; Female; Kinetics; Magnesium; Magnesium Chloride; Oocytes; Putrescine; Spermidine; Spermine; Thymine Nucleotides | 1984 |
Enzymatic determination of polyamines. Polyamines as biochemical markers for cancer.
Topics: Adult; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Creatinine; Female; Humans; Leukemia; Male; Middle Aged; Polyamines; Putrescine; Spermidine; Spermine | 1983 |
Polyamines enhance readthrough of the UGA termination codon in a mammalian messenger RNA.
Topics: Animals; Codon; Gene Expression Regulation; Globins; Peptide Chain Termination, Translational; Putrescine; Rabbits; RNA, Messenger; RNA, Transfer; Spermidine; Spermine | 1983 |
Beta-adrenergic stimulation of Ca2+ fluxes, endocytosis, hexose transport, and amino acid transport in mouse kidney cortex is mediated by polyamine synthesis.
Topics: Amino Acids; Animals; Biological Transport; Calcium; Carrier Proteins; Deoxyglucose; Endocytosis; Female; Hexoses; Isoproterenol; Kidney Cortex; Kinetics; Mice; Mice, Inbred A; Monosaccharide Transport Proteins; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1983 |
Kinetics of activation of casein kinase II by polyamines and reversal of 2,3-bisphosphoglycerate inhibition.
Topics: 2,3-Diphosphoglycerate; Casein Kinases; Diphosphoglyceric Acids; Enzyme Activation; Enzyme Inhibitors; Kinetics; Magnesium; Osmolar Concentration; Polyamines; Protein Kinases; Putrescine; Spermidine; Spermine | 1984 |
Inhibition of cells in culture by polyamines does not depend on the presence of ruminant serum.
Topics: Animals; Cattle; Cell Division; Clone Cells; Granulocytes; Humans; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Spermine; T-Lymphocytes | 1983 |
Radiosensitization of hypoxic HeLa S3 cells in vitro by a new type of radiosensitizer: spermine and spermidine amides with nitro groups.
Topics: Cell Survival; Cobalt Radioisotopes; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Gamma Rays; HeLa Cells; Humans; Misonidazole; Oxygen; Radiation-Sensitizing Agents; Spermidine; Spermine | 1983 |
Polyamines in Trichomonas vaginalis.
Topics: Animals; Eukaryota; Mammals; Polyamines; Putrescine; Species Specificity; Spermidine; Spermine; Trichomonas vaginalis | 1983 |
Putrescine--a potent endogenous anti-inflammatory substance in inflammatory exudates.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dimethylnitrosamine; Exudates and Transudates; Male; Putrescine; Rats; Spermidine; Spermine; Time Factors; Tissue Extracts | 1983 |
Development of new hypoxic cell sensitizers: amides of nitrobenzoic acid with spermidine and spermine.
Topics: Cell Survival; HeLa Cells; Humans; Hypoxia; Misonidazole; Radiation-Sensitizing Agents; Spermidine; Spermine | 1983 |
Gas chromatographic-mass spectrometric analysis of polyamines and polyamine conjugates.
Topics: Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Polyamines; Putrescine; Spermidine; Spermine | 1983 |
Polyamine levels in normal human skin. A comparative study of pure epidermis, pure dermis, and suction blister fluid.
Topics: Adult; Aged; Blister; Female; Humans; Male; Middle Aged; Polyamines; Putrescine; Skin; Spermidine; Spermine | 1983 |
Cytolethal sensitivity of human lymphoid cells to glucocorticoids and oxidised polyamines.
Topics: Cell Division; Cell Line; Cell Survival; Dexamethasone; Drug Resistance; Glucocorticoids; Humans; Lymphocytes; Polyamines; Spermidine; Spermine | 1983 |
The influence of cysteine and methionine supplements on polyamine biosynthesis in the rat.
Topics: Adenosylmethionine Decarboxylase; Animals; Brain; Cysteine; Kidney; Liver; Male; Methionine; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1983 |
Polyamines and intestinal growth--increased polyamine biosynthesis after jejunectomy.
Topics: Animals; Cell Division; DNA; Female; Ileum; Intestinal Mucosa; Jejunum; Kinetics; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Regeneration; Spermidine; Spermine | 1983 |
Differential promotion and suppression of Z leads to B transitions in poly[d(G-C)] by histone subclasses, polyamino acids and polyamines.
Topics: Animals; Circular Dichroism; Histones; Kinetics; Nucleic Acid Conformation; Peptides; Polyamines; Polydeoxyribonucleotides; Polylysine; Protamines; Species Specificity; Spermidine; Spermine; Structure-Activity Relationship | 1983 |
Determination of polyamines in human blood by electron-capture gas-liquid chromatography.
Topics: Adult; Chromatography, Gas; Erythrocytes; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Humans; Male; Polyamines; Spermidine; Spermine | 1983 |
Changes in diamine and polyamine metabolism in the duct-ligated submaxillary and sublingual glands of the rat.
Topics: Animals; Histamine; Histidine Decarboxylase; Ligation; Male; Organ Size; Ornithine Decarboxylase; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Sublingual Gland; Submandibular Gland | 1983 |
Polyamines in normal and cataractous human lenses: evidence for post-translational modification.
Topics: Aged; Animals; Cataract; Cattle; Chromatography, High Pressure Liquid; Crystallins; Eye Proteins; Humans; Lens, Crystalline; Middle Aged; Polyamines; Protein Processing, Post-Translational; Putrescine; Spermidine; Spermine | 1983 |
Heparin-sepharose as a tool in the subcellular fractionation of a polyamine-rich organ (rat ventral prostate).
Topics: Animals; Cell Fractionation; Cell Nucleus; Golgi Apparatus; Heparin; Humans; Male; Polyamines; Prostate; Putrescine; Rats; Sepharose; Spermidine; Spermine | 1983 |
Interactions between bis(guanylhydrazones) and polyamines in isolated mitochondria.
Topics: Animals; Antineoplastic Agents; Carbanilides; Dinitrophenols; Drug Interactions; Guanidines; In Vitro Techniques; Intracellular Membranes; Leukemia L1210; Liver Neoplasms, Experimental; Mitochondria; Mitochondria, Liver; Mitoguazone; Oxygen Consumption; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1983 |
Effects of polyamines on the first division cycle of Xenopus laevis eggs.
Topics: Animals; Cell Division; Female; Microinjections; Oocytes; Ovum; Putrescine; Spermidine; Spermine; Xenopus laevis | 1984 |
Cerebral polyamine metabolism: inhibition of spermidine biosynthesis by dicyclohexylamine.
Topics: Amines; Animals; Brain; Cyclohexylamines; Kinetics; Male; Mice; Polyamines; Rats; Rats, Inbred Strains; Spermidine; Spermidine Synthase; Spermine; Transferases | 1984 |
Relation between induction of rat hepatic ornithine decarboxylase activity by tumor promoters 12-O-tetradecanoylphorbol-13-acetate and phenobarbital and levels of the polyamines putrescine, spermidine and spermine, in vivo; differential effects of retinyl
Topics: Animals; Diterpenes; Enzyme Induction; Female; Kinetics; Liver; Ornithine Decarboxylase; Phorbols; Putrescine; Rats; Rats, Inbred Strains; Retinyl Esters; Spermidine; Spermine; Tetradecanoylphorbol Acetate; Vitamin A | 1984 |
Reversal of the antiproliferative effect of the antiestrogen tamoxifen by polyamines in breast cancer cells.
Topics: Animals; Cell Division; Cells, Cultured; Drug Antagonism; Female; Kinetics; Mammary Neoplasms, Experimental; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Tamoxifen | 1984 |
Effects of polyamines on platelet aggregation.
Topics: Adenosine Diphosphate; Adolescent; Adult; Epinephrine; Female; Humans; Male; Platelet Aggregation; Spermidine; Spermine; Stimulation, Chemical | 1984 |
Formation of pyrrolidine by anaerobic polyamine degradation.
Topics: Anaerobiosis; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Kinetics; Mass Spectrometry; Oxidation-Reduction; Polyamines; Putrescine; Pyrrolidines; Spermidine; Spermine | 1984 |
Total polyamines and their non-alpha-amino acid metabolites simultaneously determined in urine by capillary gas chromatography, with nitrogen-phosphorus detector; and some clinical applications.
Topics: Adolescent; Adult; Aged; Amino Acids, Diamino; Cadaverine; Child; Child, Preschool; Chromatography, Gas; Circadian Rhythm; Diamines; Female; Humans; Infant; Infant, Newborn; Lymphoma; Male; Melanoma; Menstruation; Middle Aged; Polyamines; Pregnancy; Spermidine; Spermine | 1984 |
Characterization of the polyamine transport system in mouse neuroblastoma cells. Effects of sodium and system A amino acids.
Topics: Amino Acids; Animals; Biological Transport; Cell Line; Ionophores; Kinetics; Mice; Neuroblastoma; Polyamines; Putrescine; Sodium; Spermidine; Spermine; Sulfhydryl Reagents | 1984 |
Polyamines in breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Female; Humans; Lymphatic Metastasis; Mastectomy; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Polyamines; Prognosis; Putrescine; Receptors, Estrogen; Spermidine; Spermine | 1984 |
X-ray diffraction studies on cation-collapsed DNA.
Topics: Animals; Cations; Cattle; DNA; Nucleic Acid Conformation; Osmolar Concentration; Polyamines; Putrescine; Spermidine; Spermine; X-Ray Diffraction | 1984 |
Polyamine metabolism in differentiating Friend erythroleukemia cells.
Topics: Animals; Biological Transport; Cell Differentiation; Cell Line; Cell Membrane; Cell Nucleus; Clone Cells; Cytosol; Kinetics; Leukemia, Experimental; Mice; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
Inactivation of yeast ornithine decarboxylase by polyamines in vivo does not result from the incorporation of polyamines into enzyme protein.
Topics: Carboxy-Lyases; Kinetics; Molecular Weight; Mutation; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Phenylmethylsulfonyl Fluoride; Protein Binding; Saccharomyces cerevisiae; Spermidine; Spermine | 1982 |
Sensitive enzymic determination of methylglyoxal bis(guanylhydrazone) in cultured cells and in animal tissues.
Topics: Adenosylmethionine Decarboxylase; Amine Oxidase (Copper-Containing); Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Guanidines; Humans; Kidney; Kinetics; Leukemia, Lymphoid; Liver; Methods; Mice; Mitoguazone; Putrescine; Rats; Spermidine; Spermine; Spleen | 1980 |
Irreversible inhibition of the early increase in ornithine decarboxylase activity following growth stimulation is required to block Ehrlich ascites tumor cell proliferation in culture.
Topics: Animals; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Cell Division; Eflornithine; Kinetics; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine | 1980 |
Polyamine depletion induces enhanced synthesis and accumulation of cadaverine in cultured Ehrlich ascites carcinoma cells.
Topics: Animals; Cadaverine; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Cells, Cultured; Diamines; Eflornithine; Female; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine | 1980 |
Polyamine metabolism in Menkes kinky hair disease.
Topics: Amine Oxidase (Copper-Containing); Brain Diseases, Metabolic; Copper; Humans; Infant; Male; Menkes Kinky Hair Syndrome; Putrescine; Spermidine; Spermine; Time Factors | 1980 |
Age-related abnormalities of circulating polyamines and diamine oxidase activity in cystic fibrosis heterozygotes and homozygotes.
Topics: Adolescent; Adult; Age Factors; Amine Oxidase (Copper-Containing); Child; Child, Preschool; Cystic Fibrosis; Female; Heterozygote; Humans; Male; Middle Aged; Putrescine; Spermidine; Spermine | 1980 |
Depletion of intracellular polyamine content does not alter the survival of 9L rat brain tumour cells after X-irradiation.
Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Cells, Cultured; DNA; DNA, Neoplasm; Eflornithine; Guanidines; Mitoguazone; Ornithine; Polyamines; Putrescine; Radiation Tolerance; Rats; Spermidine; Spermine; X-Rays | 1980 |
Depletion of 9L rat brain tumor cell polyamine content by treatment with D,L-alpha-difluoromethylornithine inhibits proliferation and the G1 to S transition.
Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Dose-Response Relationship, Drug; Eflornithine; Interphase; Ornithine; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1981 |
Abnormal regulation of methylthioadenosine and polyamine metabolism in methylthioadenosine phosphorylase-deficient human leukemic cell lines.
Topics: Adenosine; Cell Line; Deoxyadenosines; Humans; Leukemia; Pentosyltransferases; Polyamines; Purine-Nucleoside Phosphorylase; Putrescine; Spermidine; Spermine; Thionucleosides | 1980 |
Ovarian function in the rat following irreversible inhibition of L-ornithine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Eflornithine; Estrus; Female; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Ovary; Ovulation; Pregnancy; Putrescine; Rats; Spermidine; Spermine | 1980 |
Dependence of adenine production upon polyamine synthesis in cultured human lymphoblasts.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Adenosylmethionine Decarboxylase; Cells, Cultured; Genetic Variation; Humans; Hypoxanthine Phosphoribosyltransferase; Leukemia, Lymphoid; Polyamines; Purine-Nucleoside Phosphorylase; Putrescine; Spermidine; Spermine; Spleen; Thionucleosides | 1981 |
Selective killing of transformed cells in combination with inhibitors of polyamine biosynthesis and S-phase specific drugs.
Topics: Cell Division; Cell Transformation, Neoplastic; Cytarabine; Drug Synergism; Eflornithine; HeLa Cells; Humans; Interphase; Ornithine; Polyamines; Spermidine; Spermine | 1981 |
Ornithine decarboxylase from Saccharomyces cerevisiae. Purification, properties, and regulation of activity.
Topics: Antigen-Antibody Complex; Carboxy-Lyases; Cycloheximide; Half-Life; Immune Sera; Immunodiffusion; Kinetics; Molecular Weight; Ornithine Decarboxylase; Saccharomyces cerevisiae; Spermidine; Spermine | 1981 |
A possible role of cadaverine in the biosynthesis of polyamines in the Japanese newt testis.
Topics: Animals; Cadaverine; Diamines; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Polyamines; Putrescine; Salamandridae; Seasons; Spermidine; Spermine; Testis; Vertebrates | 1981 |
Effects of inhibitors of ornithine and S-adenosylmethionine decarboxylases on L6 myoblast proliferation.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Cells, Cultured; Eflornithine; Mitoguazone; Muscles; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1982 |
Compartmentalization of polyamines in mammalian cells.
Topics: Animals; Cell Compartmentation; Cell Cycle; Cell Fractionation; Cell Line; Cell Nucleus; Cytoplasm; DNA; Haplorhini; Kidney; Polyamines; Putrescine; Spermidine; Spermine | 1982 |
Polyamine biosynthesis and skin tumor promotion: inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase alpha-difluoromethylornithine.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drug Antagonism; Eflornithine; Kinetics; Mice; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Phorbols; Polyamines; Putrescine; Skin; Skin Neoplasms; Spermidine; Spermine; Tetradecanoylphorbol Acetate | 1982 |
Ornithine decarboxylase and polyamines in tissues of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase.
Topics: Animals; Animals, Newborn; Brain; Carboxy-Lyases; Eflornithine; Female; Heart; Kidney; Myocardium; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1982 |
Polyamine depletion influences drug-induced chromosomal damage.
Topics: Animals; Carmustine; Chromosomes; Cisplatin; DNA; Eflornithine; Nucleic Acid Conformation; Ornithine; Polyamines; Putrescine; Rats; Sister Chromatid Exchange; Spermidine; Spermine | 1982 |
Metabolism of putrescine in the pregnant rat.
Topics: Animals; Carbon Dioxide; Female; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1981 |
Polyamine cytochemistry. Use of a novel o-phtalaldehyde method for visualizing spermidine and spermine. Comparisons to the formaldehyde-fluorescamine method.
Topics: Aldehydes; Animals; Cats; Eflornithine; Fluorescamine; Formaldehyde; Histocytochemistry; Hydrogen-Ion Concentration; Methods; o-Phthalaldehyde; Ornithine; Polyamines; Rats; Spermidine; Spermine; Spiro Compounds | 1982 |
Polyamines and polyamine biosynthesis in cells exposed to hyperthermia.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Guanidines; Hot Temperature; Mitoguazone; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Time Factors | 1983 |
Biosynthesis of polyamines in mouse brain: effects of methionine sulfoximine and adenosylhomocysteine.
Topics: Animals; Brain; Homocysteine; Male; Methionine Sulfoximine; Methylation; Mice; Polyamines; Putrescine; S-Adenosylhomocysteine; Spermidine; Spermine | 1983 |
CSF polyamines in childhood.
Topics: Age Factors; Brain Neoplasms; Child; Child, Preschool; Encephalocele; Humans; Hydrocephalus; Meningomyelocele; Polyamines; Putrescine; Spermidine; Spermine | 1983 |
Role of polyamines in expression of the differentiated phenotype of chondrocytes: effect of DL-alpha-hydrazino-delta-aminovaleric acid (DL-HAVA), an inhibitor of ornithine decarboxylase, on chondrocytes treated with parathyroid hormone.
Topics: Animals; Carboxy-Lyases; Cartilage; Cell Differentiation; Cells, Cultured; DNA Replication; Kinetics; Male; Ornithine; Ornithine Decarboxylase Inhibitors; Parathyroid Hormone; Peptide Fragments; Polyamines; Putrescine; Rabbits; Spermidine; Spermine; Teriparatide | 1983 |
Acetylation of polyamines in mouse brain: subcellular and regional distribution.
Topics: Acetylation; Animals; Brain; Cadaverine; Kinetics; Male; Mice; Mice, Inbred C57BL; Pargyline; Polyamines; Putrescine; Spermidine; Spermine | 1983 |
Supramolecular forms of actin induced by polyamines; an electron microscopic study.
Topics: Actins; Animals; Cell Division; In Vitro Techniques; Microscopy, Electron; Protein Conformation; Rabbits; Spermidine; Spermine | 1983 |
Leishmania tropica major: effect of paromomycin and pentamidine on polyamine levels in the skin of normal and infected mice.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Drug Evaluation, Preclinical; Leishmaniasis; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Ornithine Decarboxylase; Paromomycin; Pentamidine; Polyamines; Putrescine; Skin; Spermidine; Spermine; Time Factors | 1983 |
Quantitation of cation binding to wheat germ ribosomes: influences on subunit association equilibria and ribosome activity.
Topics: Cations; Dialysis; Magnesium; Phenylalanine; Protein Biosynthesis; Ribosomes; Spermidine; Spermine; Triticum | 1983 |
Spermidine in the venom of the scorpion, Palamneus phipsoni.
Topics: Animals; Scorpion Venoms; Spermidine; Spermine | 1983 |
[Analytical and clinical aspects of polyamines].
Topics: Humans; Kidney Diseases; Neoplasms; Putrescine; Spermidine; Spermine | 1983 |
Circadian rhythmicity of polyamine urinary excretion.
Topics: Circadian Rhythm; Female; Humans; Male; Polyamines; Putrescine; Spermidine; Spermine | 1983 |
Epidermal polyamine profiles after multiple exposures to ultraviolet radiation.
Topics: Animals; Epidermis; Female; Mice; Mice, Hairless; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Time Factors; Ultraviolet Rays | 1983 |
Polyamines. Biological modulators of membrane fusion.
Topics: Animals; Cattle; Cell Fusion; Cell Membrane; Cholesterol; Kinetics; Liposomes; Models, Biological; Polyamines; Spermidine; Spermine | 1983 |
Effects of single applications of 12-O-tetradecanoylphorbol-13-acetate, mezerein, or ethylphenylpropiolate on DNA synthesis and polyamine levels in hairless mouse epidermis.
Topics: Alkynes; Animals; Antineoplastic Agents, Phytogenic; Diterpenes; DNA Replication; Female; Kinetics; Male; Mice; Mice, Nude; Phorbol Esters; Phorbols; Polyamines; Putrescine; Skin; Spermidine; Spermine; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Polyamines stimulate the binding of hexokinase type II to mitochondria.
Topics: Animals; Glucose-6-Phosphate; Glucosephosphates; Hexokinase; Isoenzymes; Magnesium; Mitochondria; Polyamines; Spermidine; Spermine | 1983 |
N1-acetylspermidine and N6-acetylspermidine in normal rat tissues and body fluids.
Topics: Animals; Body Fluids; Male; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1983 |
Induction of cytokinesis by interaction between actin and polyamines.
Topics: Actins; Animals; Cell Cycle; Cytochalasin B; Cytochalasin D; Cytochalasins; In Vitro Techniques; Polyamines; Spermidine; Spermine | 1980 |
Elevation of serum polyamines in malignant lymphomas and acute myeloid leukemia.
Topics: Adult; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lymphoma; Male; Methods; Oxidoreductases; Polyamines; Putrescine; Spermidine; Spermine; Venoms | 1980 |
Evidence for a naturally occurring anti-spermine antibody in normal rabbit serum.
Topics: Animals; Antibody Specificity; Carrier Proteins; Cross Reactions; Haptens; Rabbits; Spermidine; Spermine | 1980 |
Alterations in polyamine levels induced by phorbol diesters and other agents that promote differentiation in human promyelocytic leukemia cells.
Topics: Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Muramidase; Phorbol Esters; Phorbols; Polyamines; Putrescine; Spermidine; Spermine; Tetradecanoylphorbol Acetate | 1981 |
Polyamines as biological markers of the effectiveness of therapy in acute leukemia.
Topics: Adolescent; Adult; Antineoplastic Agents; Female; Follow-Up Studies; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Putrescine; Spermidine; Spermine | 1980 |
Polyamines are inhibitors of gastric acid secretion.
Topics: Animals; Biological Transport; Cell-Free System; Gastric Juice; Gastric Mucosa; Hydrogen-Ion Concentration; Microsomes; Polyamines; Potassium; Spermidine; Spermine | 1982 |
The finding and significance of spermidine and spermine in Fraction 5.
Topics: Dansyl Compounds; DNA Replication; Humans; Lymphocyte Activation; Spermidine; Spermine; Spleen; T-Lymphocytes; Thymus Gland; Tissue Extracts | 1982 |
Ornithine decarboxylase activity and cell cycle regulation in Saccharomyces cerevisiae.
Topics: Carboxy-Lyases; Cell Cycle; Interphase; Ornithine Decarboxylase; Phenanthrolines; Saccharomyces cerevisiae; Spermidine; Spermine | 1980 |
Regulatory mutations affecting ornithine decarboxylase activity in Saccharomyces cerevisiae.
Topics: Carboxy-Lyases; Genes, Regulator; Genetic Linkage; Mutation; Ornithine Decarboxylase; Putrescine; Saccharomyces cerevisiae; Spermidine; Spermine; Spermine Synthase | 1980 |
Elevated polyamine content in erythrocytes of malignant lymphoma patients.
Topics: Adolescent; Adult; Aged; Erythrocytes; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasm Staging; Spermidine; Spermine | 1980 |
Changes in polyamines, RNA synthesis, and cell proliferation during matrix-induced cartilage, bone, and bone marrow development.
Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Bone and Bones; Bone Marrow; Bone Transplantation; Cartilage; Cell Division; DNA; Male; Ornithine Decarboxylase; Putrescine; Rats; Spermidine; Spermine; Transplantation, Homologous | 1981 |
Induction of choline transport and its role in the stimulation of the incorporation of choline into phosphatidylcholine by polyamines in a polyamine auxotroph of Saccharomyces cerevisiae.
Topics: Biological Transport; Choline; Kinetics; Mitoguazone; Phosphatidylcholines; Polyamines; Putrescine; Saccharomyces cerevisiae; Spermidine; Spermine | 1981 |
Changes in ingestive behavior, serum glucose and free fatty acids concentrations in rats following intracerebroventricular injection of spermine.
Topics: Animals; Blood Glucose; Drinking; Eating; Fatty Acids, Nonesterified; Hypothalamus; Injections, Intraventricular; Insulin; Male; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1981 |
[Polyamine levels in blood and plasma of patients with malignant melanoma].
Topics: Adult; Aged; Cadaverine; Clinical Laboratory Techniques; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Polyamines; Prognosis; Putrescine; Spermidine; Spermine | 1982 |
Polyamine transport in Aspergillus nidulans.
Topics: Aspergillus nidulans; Azides; Biological Transport, Active; Cycloheximide; Kinetics; Nitrogen; Polyamines; Putrescine; Sodium Azide; Spermidine; Spermine | 1982 |
The influence of spermidine (polyamines) on DNA depurination in vitro.
Topics: DNA, Bacterial; Escherichia coli; Kinetics; Plasmids; Putrescine; Spermidine; Spermine | 1982 |
Regulation of putrescine metabolism in Ehrlich ascites carcinoma cells exposed to hypotonic medium.
Topics: Adenosylmethionine Decarboxylase; Animals; Carcinoma, Ehrlich Tumor; Culture Media; Kinetics; Mice; Ornithine Decarboxylase; Osmolar Concentration; Putrescine; Spermidine; Spermine | 1982 |
Effect of cations on the acetylation of chromatin in vitro.
Topics: Acetylation; Acetyltransferases; Animals; Cations; Cell Nucleus; Chromatin; Histone Acetyltransferases; In Vitro Techniques; Liver; Magnesium; Rats; Saccharomyces cerevisiae Proteins; Sodium; Spermidine; Spermine | 1982 |
Chromophoric determination of putrescine, spermidine and spermine with dabsyl chloride by high-performance liquid chromatography and thin-layer chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Female; Male; Putrescine; Rats; Rats, Inbred Strains; Reference Values; Spermidine; Spermine; Tissue Distribution | 1982 |
Comparison of chromosomal structures isolated under different conditions.
Topics: Animals; Cell Fractionation; Cells, Cultured; Chelating Agents; Chickens; Chromosomes; DNA; Genes; Hydrogen-Ion Concentration; Nucleosomes; Ovalbumin; Spermidine; Spermine | 1982 |
An ornithine decarboxylase-deficient mutant of Chinese hamster ovary cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cell Division; Cell Line; Cricetinae; Cricetulus; Ethyl Methanesulfonate; Female; Kinetics; Mutation; Ornithine Decarboxylase; Ovary; Putrescine; Spermidine; Spermine | 1982 |
Testosterone-dependent sexual dimorphism of the mouse kidney is mediated by polyamines.
Topics: Animals; Castration; Female; Kidney; Male; Mice; Ornithine Decarboxylase; Polyamines; Putrescine; Sex Factors; Spermidine; Spermine; Testosterone | 1982 |
Single-step high-performance liquid chromatographic method for the analysis of acetylated polyamines.
Topics: Chromatography, High Pressure Liquid; Humans; Leukemia; Male; Melanoma; Mesothelioma; Putrescine; Reference Values; Spermidine; Spermine | 1982 |
Actin-polyamines interaction : relationship between physicochemical properties and cytokinesis induction.
Topics: Actins; Animals; Kinetics; Macromolecular Substances; Muscles; Nephelometry and Turbidimetry; Protein Binding; Rabbits; Spermidine; Spermine | 1982 |
[In vitro analysis of the adsorbent capacity of activated charcoal versus polyamines in a recirculating circuit].
Topics: Adsorption; Charcoal; Chromatography, Thin Layer; In Vitro Techniques; Polyamines; Putrescine; Spectrometry, Fluorescence; Spermidine; Spermine | 1982 |
Further evidence for the use of polyamines as biochemical markers for malignant tumors.
Topics: Breast Neoplasms; Clinical Laboratory Techniques; Female; Genital Neoplasms, Female; Humans; Male; Neoplasm Metastasis; Neoplasms; Prostatic Neoplasms; Putrescine; Spermidine; Spermine; Stomach Neoplasms | 1982 |
Widespread occurrence of norspermidine and norspermine in eukaryotic algae.
Topics: Chromatography, Paper; Eukaryota; Spermidine; Spermine | 1982 |
Polyamines alter the phosphorylation pattern of chromatin proteins by endogenous protein kinases.
Topics: Animals; Cell Nucleus; Chromatin; Kinetics; Liver; Nucleoproteins; Phosphorylation; Polyamines; Protein Kinases; Putrescine; Rats; Spermidine; Spermine | 1982 |
Cutaneous polyamines in psoriasis.
Topics: Humans; Ornithine Decarboxylase; Polyamines; Psoriasis; Putrescine; Skin; Spermidine; Spermine | 1982 |
Mass spectrometric identification of isoputreanine, a metabolite of spermidine and/or spermine, in human urine.
Topics: Amino Acids, Diamino; Humans; Lymphoma; Mass Spectrometry; Spermidine; Spermine | 1982 |
Purification and characterization of extracellular polyamine oxidase produced by Penicillium sp. no. PO-1.
Topics: Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Penicillium; Polyamine Oxidase; Spermidine; Spermine; Substrate Specificity | 1982 |
Specific interaction of spermine with Cibacron blue F3ga.
Topics: Anthracenes; Chemical Phenomena; Chemistry; Putrescine; Spectrophotometry; Spermidine; Spermine; Triazines | 1982 |
Polyamine metabolism during the perinatal development of the rabbit right and left ventricle.
Topics: Age Factors; Animals; Animals, Newborn; Heart; Heart Ventricles; Myocardium; Organ Size; Ornithine Decarboxylase; Polyamines; Putrescine; Rabbits; Spermidine; Spermine | 1982 |
Polyamine metabolism in muscle: differential response to tenotomy and denervation in the soleus and gastrocnemius muscle of adult rats.
Topics: Animals; Female; Hindlimb; Male; Muscle Denervation; Muscles; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Tendons | 1982 |
Polyamine biosynthesis and interconversion in rodent tissues.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Kidney; Liver; Mice; Muscles; Ornithine Decarboxylase; Polyamines; Rats; Spermidine; Spermine | 1982 |
Polyamine oxidase-mediated killing of African trypanosomes.
Topics: Animals; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Spermine; Trypanosoma; Trypanosoma brucei brucei | 1982 |
Formation of polyamines in the rumen of goats during growth.
Topics: Adenosylmethionine Decarboxylase; Animals; Female; Goats; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Rumen; Spermidine; Spermine | 1982 |
Psoriasiform dermatosis in a rhesus monkey. Epidermal labeling indexes, polyamines, and histopathologic findings.
Topics: Animals; Disease Models, Animal; DNA; Humans; Infant, Newborn; Macaca mulatta; Psoriasis; Putrescine; Skin; Spermidine; Spermine | 1982 |
Isoproterenol-induced responses in the regional polyamine metabolism of the rat heart.
Topics: Animals; Heart; Heart Ventricles; Isoproterenol; Male; Myocardium; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Tissue Distribution | 1982 |
Activation of tubulinyl-tyrosine carboxypeptidase by spermine, spermidine and putrescine.
Topics: Animals; Brain; Carboxypeptidases; Enzyme Activation; In Vitro Techniques; Magnesium; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1982 |
Conversion of exogenous spermidine into putrescine after administration to rats.
Topics: Animals; Intestine, Small; Kidney; Kinetics; Liver; Male; Myocardium; Organ Specificity; Polyamines; Prostate; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1982 |
Cellular content and biosynthesis of polyamines during rooster spermatogenesis.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Separation; Centrifugation, Density Gradient; Chickens; Male; Ornithine Decarboxylase; Putrescine; Spermatogenesis; Spermatozoa; Spermidine; Spermine; Testis | 1982 |
Inhibition of the bioenergetic functions of isolated rat liver mitochondria by polyamines.
Topics: Animals; Energy Metabolism; In Vitro Techniques; Kinetics; Liver; Mitochondria, Liver; Oxygen Consumption; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1982 |
Polyamines and membrane proteins in sickle cell disease.
Topics: Anemia, Sickle Cell; Erythrocytes, Abnormal; Hemoglobin A; Hemoglobin C; Hemoglobin, Sickle; Humans; Membrane Proteins; Polyamines; Spectrin; Spermidine; Spermine; Thalassemia | 1982 |
Toxic effects of maternal methadone administration on cardiac development in the neonatal rat: potential participation of altered polyamine levels in growth impairment.
Topics: Aging; Animals; Animals, Newborn; Female; Heart; Methadone; Myocardium; Ornithine Decarboxylase; Polyamines; Pregnancy; Prenatal Exposure Delayed Effects; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1982 |
Affinity of putrescine, spermidine and spermine for pigmented tissues.
Topics: Animals; Cattle; Eye; Kidney; Liver; Male; Melanins; Melanocytes; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Ornithine; Ornithine Decarboxylase; Putrescine; Species Specificity; Spermidine; Spermine; Tissue Distribution | 1982 |
Developmental changes in mouse brain polyamine metabolism.
Topics: Adenosylmethionine Decarboxylase; Aging; Animals; Brain; Carboxy-Lyases; Kinetics; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1982 |
Polyamines modulate phosphorylation and acetylation of non-histone chromosomal proteins of the cerebral cortex of rats of various ages.
Topics: Acetylation; Aging; Animals; Cerebral Cortex; Chromosomal Proteins, Non-Histone; DNA; Histones; In Vitro Techniques; Phosphorylation; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1982 |
Further observations on four subgroups of normal variant short stature.
Topics: Body Height; Child; Female; Growth Disorders; Growth Hormone; Humans; Insulin-Like Growth Factor I; Male; Polyamines; Putrescine; Radioimmunoassay; Radioligand Assay; Sleep; Somatomedins; Spermidine; Spermine | 1980 |
Altered polyamine excretion in Duchenne muscular dystrophy.
Topics: Child; Creatinine; Erythrocytes; Humans; Male; Muscular Dystrophies; Polyamines; Putrescine; Spermidine; Spermine | 1981 |
On the biogenesis of diamines and polyamines in the pregnant rat.
Topics: Animals; Cadaverine; Castration; Diamines; Female; Fetus; Histamine; Hysterectomy; Methylhistamines; Placenta; Polyamines; Pregnancy; Pregnancy, Animal; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1981 |
Effect of unilateral ureteral obstruction on renal polyamine levels in rats.
Topics: Animals; Female; Kidney; Kinetics; Polyamines; Putrescine; Rats; Spermidine; Spermine; Ureteral Obstruction | 1981 |
Isolation and identification of polyamine metabolites in urine of animals.
Topics: Animals; Chromatography, Ion Exchange; Kinetics; Male; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1980 |
Conjugation of polyamines in mammalian cells in culture.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cricetinae; Embryo, Mammalian; Guanosine; Kidney; Kinetics; Mice; Mitoguazone; Polyamines; Putrescine; Spermidine; Spermine; Thionucleosides | 1980 |
Polyamines and polyamine complexes: analytical comments.
Topics: Acetylation; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Polyamines; Putrescine; Radioimmunoassay; Spermidine; Spermine | 1980 |
The effect of polyamines of DNA synthesis in vitro.
Topics: Animals; Cell Division; Cell Line; Cricetinae; DNA Polymerase I; DNA Polymerase II; DNA Replication; DNA-Directed DNA Polymerase; Kidney; Kinetics; Polyamines; Spermidine; Spermine | 1981 |
Urinary polyamine excretion in man. II. Influence of menstrual cycle.
Topics: Adult; Diamines; Female; Follicular Phase; Humans; Luteal Phase; Menstruation; Polyamines; Putrescine; Spermidine; Spermine | 1980 |
[In vitro variations of hepatic glycogenolysis after incubation of rat liver slices in the presence of polyamines].
Topics: Animals; Liver; Liver Glycogen; Liver Regeneration; Male; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1980 |
Reassociation of eukaryotic ribosomal subunits and polyamine concentration in Yoshida ascites hepatoma and Ehrlich ascites carcinoma cells during growth.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line; Liver Neoplasms, Experimental; Mice; Polyamines; Putrescine; Rats; Ribosomes; Spermidine; Spermine | 1980 |
Acetylderivatives as intermediates in polyamine catabolism.
Topics: Animals; Kinetics; Liver; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Rats; Spermidine; Spermine; Substrate Specificity | 1981 |
Methionine utilization in long-term human lymphoid cell lines.
Topics: Blood Proteins; Cell Count; Cell Line; Cell Survival; Humans; Kinetics; Lymphocytes; Methionine; S-Adenosylmethionine; Spermidine; Spermine | 1981 |
Polyamines in some tarantula venoms.
Topics: Arthropod Venoms; Cadaverine; Polyamines; Putrescine; Spermidine; Spermine; Spider Venoms | 1980 |
Urinary polyamines in cancer.
Topics: Humans; Neoplasms; Putrescine; Spermidine; Spermine | 1980 |
Polyamine-activated protein kinase reaction from nuclei and nucleoli of Physarum polycephalum which phosphorylates a unique Mr 70 000 nonhistone protein.
Topics: Cell Nucleolus; Cell Nucleus; Chromosomal Proteins, Non-Histone; Enzyme Activation; Kinetics; Molecular Weight; Phosphorylation; Physarum; Polyamines; Protein Kinases; Spermidine; Spermine | 1981 |
Polyamine accumulation in normal and denervated neonatal muscle.
Topics: Aging; Animals; Animals, Newborn; Female; Male; Muscle Denervation; Muscles; Polyamines; Putrescine; Rats; Sciatic Nerve; Spermidine; Spermine | 1981 |
Initial stages of endogenous DNA degradation in rat liver nuclei isolated and incubated in the presence of Mg2+ or polyamines.
Topics: Animals; Cell Nucleus; DNA; Drug Stability; Electrophoresis, Agar Gel; Liver; Magnesium; Magnesium Chloride; Rats; Spermidine; Spermine | 1981 |
Prevention by polyamines of the curative effect of amicarbalide and imidocarb for Trypanosoma brucei infections in mice.
Topics: Amidines; Animals; Carbanilides; Female; Imidocarb; Male; Mice; Polyamines; Spermidine; Spermine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1981 |
Enhancement of lipid peroxidation in rat brain mitochondria by polyamines.
Topics: Animals; Ascorbic Acid; Brain; Kinetics; Lipid Peroxides; Male; Malondialdehyde; Mitochondria; Rats; Spermidine; Spermine | 1981 |
Altered muscle polyamine levels in human neuromuscular diseases.
Topics: Adolescent; Adult; Aged; Child; Humans; Middle Aged; Muscles; Muscular Dystrophies; Neuromuscular Diseases; Putrescine; Spermidine; Spermine | 1981 |
The determination of N1-acetylspermine in mouse liver.
Topics: Animals; Carbon Tetrachloride Poisoning; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Liver; Male; Mass Spectrometry; Mice; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Spermidine; Spermine | 1981 |
Uptake and excretion of polyamines from baby hamster kidney cells (BHK-21/C13). The effect of serum on confluent cell cultures.
Topics: Animals; Biological Transport; Blood; Cell Line; Cricetinae; Culture Media; Kidney; Polyamines; Putrescine; Spermidine; Spermine | 1981 |
[Cerebral and hepatic arginase and polyamines in the mechanisms of the protective effect of arginine in hyperoxia].
Topics: Animals; Arginase; Arginine; Brain; Brain Chemistry; Liver; Male; Oxygen; Polyamines; Rats; Spermidine; Spermine | 1981 |
A polyamine-dependent protein kinase from bovine epididymal spermatozoa.
Topics: Animals; Cattle; Epididymis; Kinetics; Magnesium; Male; Molecular Weight; Protein Kinases; Spermatozoa; Spermidine; Spermine | 1981 |
Effects of spermine and spermidine on gastric emptying in rats.
Topics: Animals; Gastric Emptying; Molecular Weight; Polyamines; Rats; Spermidine; Spermine; Structure-Activity Relationship | 1981 |
Diurnal levels of polyamines and activities of ornithine and S-adenosyl-L-methionine decarboxylases in mouse brain.
Topics: Adenosylmethionine Decarboxylase; Animals; Brain; Carboxy-Lyases; Circadian Rhythm; Male; Mice; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1981 |
Covalent binding of polyamines to proteins in HTC cells.
Topics: Cells, Cultured; Polyamines; Protein Binding; Proteins; Putrescine; Spermidine; Spermine | 1981 |
Reduction of increased polyamine levels in psoriatic lesions by retinoid and PUVA treatments.
Topics: Adult; Aged; Etretinate; Humans; Middle Aged; Photochemotherapy; Polyamines; Psoriasis; Putrescine; PUVA Therapy; Skin; Spermidine; Spermine; Tretinoin | 1981 |
Intrahepatic polyamine levels during rat liver carcinogenesis induced by N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Body Weight; Female; Liver Neoplasms; Neoplasms, Experimental; Organ Size; Polyamines; Putrescine; Rats; Spermidine; Spermine; Time Factors | 1981 |
Reversal of heparin inhibition of nuclear protein kinase NII by polyamines and histones.
Topics: Animals; Caseins; Cell Nucleus; Chromatography, Affinity; Heparin; Histones; Liver; Phosvitin; Polyamines; Protein Kinase Inhibitors; Protein Kinases; Putrescine; Rats; Spermidine; Spermine | 1981 |
Pulmonary polyamine permeability factor.
Topics: Animals; Capillary Permeability; Cattle; In Vitro Techniques; Lung; Microcirculation; Molecular Weight; Rats; Skin; Spermidine; Spermine; Tissue Extracts | 1981 |
The biosynthesis of polyamines in the brain of audiogenic seizure-susceptible and -resistant deermice.
Topics: Acoustic Stimulation; Animals; Brain; Chromatography, High Pressure Liquid; Methionine; Peromyscus; Polyamines; Putrescine; S-Adenosylhomocysteine; S-Adenosylmethionine; Seizures; Spermidine; Spermine | 1981 |
A possible role of arginase in the regulation of polyamine biosynthesis in the rat thyroid.
Topics: Amino Acids; Animals; Arginase; Arginine; DNA; Male; Methylthiouracil; Ornithine; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Thyroid Gland; Thyrotropin | 1981 |
Alterations of red blood cells' polyamines during pregnancy and neonatal period.
Topics: Cadaverine; Chromatography, High Pressure Liquid; Erythrocytes; Female; Fetal Blood; Humans; Infant, Newborn; Polyamines; Pregnancy; Putrescine; Spermidine; Spermine | 1981 |
Influence of various cations on the equilibria between wheat germ ribosomes and their subunits.
Topics: Calcium; Cations, Divalent; Cations, Monovalent; Kinetics; Magnesium; Plants; Ribosomes; Spermidine; Spermine; Triticum | 1981 |
Red cell free polyamine concentrations in patients on maintenance hemodialysis.
Topics: Adult; Aged; Erythrocytes; Female; Humans; Male; Middle Aged; Polyamines; Renal Dialysis; Spermidine; Spermine; Uremia | 1981 |
Activation by polyamines of the acetylation of endogenous histones in isolated chromatin and nuclei from Artemia.
Topics: Acetyl Coenzyme A; Acetyltransferases; Animals; Artemia; Calcium; Cell Nucleus; Chromatin; Histone Acetyltransferases; Histones; Kinetics; Polyamines; Putrescine; Saccharomyces cerevisiae Proteins; Spermidine; Spermine | 1981 |
Essential role of the polyamines in early chick embryo development.
Topics: Animals; Chick Embryo; Cleavage Stage, Ovum; Gastrula; Nervous System; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1980 |
Erythrocyte polyamine determinations in patients with head and neck cancer.
Topics: Carcinoma, Squamous Cell; Erythrocytes; Head and Neck Neoplasms; Humans; Polyamines; Spermidine; Spermine | 1981 |
Cytochalasin B inhibits polyamine biosynthesis in HeLa cells.
Topics: Adenosylmethionine Decarboxylase; Cytochalasin B; HeLa Cells; Humans; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1981 |
[A potential role of polyamines in goiter formation (author's transl)].
Topics: Adenosylmethionine Decarboxylase; Animals; Goiter; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Thyroid Gland; Thyrotropin | 1981 |
On the formation of amino acids deriving from spermidine and spermine.
Topics: Amino Acids; Amino Acids, Diamino; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Guanidines; In Vitro Techniques; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Pargyline; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1981 |
Antitumor effect of dicyclohexylammonium sulfate, a potent inhibitor of spermidine, synthase.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cyclohexylamines; Enzyme Inhibitors; Female; Male; Mice; Mice, Inbred Strains; Quaternary Ammonium Compounds; Sarcoma 180; Spermidine; Spermidine Synthase; Spermine; Transferases | 1981 |
Effects of spermidine and spermine on DNA synthesis in isolated nuclei and on the activity of DNA polymerases alpha and beta from the mammary gland of pregnant rabbit.
Topics: Animals; Cell Nucleus; DNA; DNA Polymerase I; DNA Polymerase II; Female; Mammary Glands, Animal; Pregnancy; Pregnancy, Animal; Rabbits; Spermidine; Spermine; Time Factors | 1981 |
Abnormal polyamine metabolism in hereditary muscular dystrophies: effect of human growth hormone.
Topics: Adolescent; Adult; Animals; Cadaverine; Child; Cricetinae; Growth Hormone; Humans; Male; Mice; Muscular Dystrophies; Muscular Dystrophy, Animal; Polyamines; Putrescine; Spermidine; Spermine; Time Factors | 1980 |
Elevated contents of spermidine and spermine in the erythrocytes of cancer patients.
Topics: Chromatography, High Pressure Liquid; Erythrocytes; Female; Humans; Male; Neoplasms; Spermidine; Spermine; Time Factors | 1980 |
Polyamines and yellow lupin aminoacyl-tRNA synthetases. Spermine and spermidine help to maintain the active structures of aminoacyl-tRNA synthetases.
Topics: Amino Acyl-tRNA Synthetases; Enzyme Activation; Phenylalanine-tRNA Ligase; Plants; Proteins; Spermidine; Spermine; Valine-tRNA Ligase | 1980 |
Estrogen increases hypothalamic and pituitary polyamine levels in ovariectomized rats.
Topics: Animals; Castration; Estradiol; Female; Hypothalamus; Kinetics; Pituitary Gland; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1980 |
Enhancement of hyperthermia-induced cytotoxicity by polyamines.
Topics: Animals; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Cricetinae; Female; Hot Temperature; Ornithine Decarboxylase; Ovary; Polyamines; Puromycin; Putrescine; Spermidine; Spermine | 1980 |
Studies on the in vitro uptake of polyamines by Girardi heart cells.
Topics: Adsorption; Cell Line; Dinitrophenols; Humans; Iodoacetates; Myocardium; Spermidine; Spermine; Time Factors | 1980 |
Interaction of polyamines with proteins of human plasma: a preferential aggregation of fibrinogen and fibronectin (cold insoluble globulin).
Topics: Blood Proteins; Fibrinogen; Fibronectins; Humans; Polyamines; Spermidine; Spermine | 1980 |
Polyamine concentrations in red cells and urine of patients with chronic renal failure.
Topics: Adult; Creatinine; Erythrocytes; Humans; Kidney Failure, Chronic; Male; Middle Aged; Putrescine; Renal Dialysis; Spermidine; Spermine | 1980 |
On the turnover of polyamines spermidine and spermine in mouse brain and other organs.
Topics: Animals; Brain; Intestine, Small; Kidney; Male; Mice; Muscles; Myocardium; Putrescine; Spermidine; Spermine; Spleen | 1980 |
Clearance of [14C] polyamines from plasma and erythrocytes in the rat.
Topics: Animals; Erythrocytes; Injections, Intravenous; Male; Polyamines; Putrescine; Rats; Spermidine; Spermine; Time Factors | 1980 |
Reversible dissociation of wheat germ ribosomal subunits: cation-dependent equilibria and thermodynamic parameters.
Topics: Kinetics; Magnesium; Molecular Weight; Plants; Potassium; Ribosomes; Spermidine; Spermine; Thermodynamics; Triticum | 1980 |
Effects of DL-alpha-methylornithine on proliferation and polyamine content of 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cell Division; Cells, Cultured; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1980 |
Polyamines stimulate suppression of amber termination codons in vitro by normal tRNAs.
Topics: Animals; Codon; Electrophoresis, Polyacrylamide Gel; Plant Viruses; Rabbits; Rats; RNA, Messenger; RNA, Transfer; RNA, Viral; Sodium Dodecyl Sulfate; Spermidine; Spermine; Stimulation, Chemical | 1980 |
The effect of polyamines on the enzymes of the 4-aminobutyric acid metabolism in mouse brain in vitro.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Animals; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Mice; Putrescine; Spermidine; Spermine; Succinate-Semialdehyde Dehydrogenase (NADP+) | 1980 |
S-adenosylmethionine levels and protein methylation during morphogenesis of Mucor racemosus.
Topics: Fungal Proteins; Methylation; Morphogenesis; Mucor; S-Adenosylmethionine; Spermidine; Spermine | 1980 |
Blood cell polyamines in children with short stature in reference to growth hormone activity.
Topics: Adolescent; Blood Cells; Child; Child, Preschool; Female; Growth Disorders; Growth Hormone; Humans; Hypopituitarism; Male; Spermidine; Spermine | 1980 |
Inhibition of Dugesia tigrina auricle regeneration by inhibitors of polyamine synthesis.
Topics: Aldehydes; Animals; Ornithine; Polyamines; Putrescine; Pyruvaldehyde; Regeneration; Spermidine; Spermine; Turbellaria | 1980 |
Change of polyamine content in mouse skin by leupeptin, a protease inhibitor, during early stage of tumorigenesis.
Topics: Animals; Benz(a)Anthracenes; Croton Oil; Leupeptins; Male; Mice; Oligopeptides; Polyamines; Skin; Skin Neoplasms; Spermidine; Spermine | 1980 |
Polyamines and biosynthetic enzymes in the rat intestinal mucosa and the influence of methylglyoxal-bis(guanylhydrazone).
Topics: Adenosylmethionine Decarboxylase; Alkaline Phosphatase; Animals; Cell Separation; Guanidines; Intestinal Mucosa; Mitoguazone; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Spermidine; Spermine; Sucrase | 1980 |
[Polyamine formation and development of functional hypertrophy in skeletal muscles with increased activity].
Topics: Animals; Arginase; Arginine; Cycloheximide; Muscles; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Physical Exertion; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1980 |
Erythrocyte polyamine levels in rats with H4IIE hepatomas before and after radiation treatment.
Topics: Animals; Buffers; Erythrocytes; Liver Neoplasms, Experimental; Neoplasm Transplantation; Polyamines; Putrescine; Rats; Spermidine; Spermine; Transplantation, Homologous | 1980 |
Polyamines in sickle cell disease.
Topics: Anemia, Sickle Cell; Erythrocyte Membrane; Erythrocytes; Hemoglobin C Disease; Humans; Polyamines; Putrescine; Sickle Cell Trait; Spermidine; Spermine; Thalassemia | 1980 |
Chromatographic resolution of two DNA polymerase activities from bloodstream forms of Trypanosoma brucei: differential responses to exogenous polyamine addition.
Topics: Animals; Cadaverine; Cations, Monovalent; DNA-Directed DNA Polymerase; Polyamines; Potassium Chloride; Putrescine; Spermidine; Spermine; Trypanosoma brucei brucei | 1980 |
Biologic markers in breast carcinoma: clinical correlations with urinary polyamines.
Topics: Breast Neoplasms; Cadaverine; Female; Humans; Polyamines; Prognosis; Putrescine; Spermidine; Spermine | 1980 |
Ornithine decarboxylase in skin.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Humans; Nucleic Acids; Ornithine Decarboxylase; Polyamines; Putrescine; Skin; Skin Diseases; Spermidine; Spermine | 1980 |
Activation of mammalian DNA ligase by polyamines.
Topics: Animals; Cattle; DNA Ligases; Enzyme Activation; Kinetics; Magnesium; Magnesium Chloride; Manganese; Polynucleotide Ligases; Putrescine; Spermidine; Spermine; Thymus Gland | 1980 |
Regulation of polyamine biosynthesis in normal and transformed hamster cells in culture.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Enzyme Induction; Fibroblasts; Ornithine Decarboxylase; Phorbols; Polyamines; Putrescine; Spermidine; Spermine; Tetradecanoylphorbol Acetate | 1980 |
Improved analysis for urinary polyamines by use of high-voltage electrophoresis on paper.
Topics: Autoanalysis; Cadaverine; Electrophoresis, Paper; Histamine; Humans; Neoplasms; Polyamines; Putrescine; Specimen Handling; Spermidine; Spermine | 1980 |
Raised polyamines in erythrocytes from melanoma-bearing mice and patients with solid tumours.
Topics: Animals; Erythrocytes; Female; Humans; Male; Melanoma; Mice; Mice, Inbred DBA; Middle Aged; Neoplasms; Neoplasms, Experimental; Polyamines; Putrescine; Spermidine; Spermine | 1980 |
A preliminary study of polyamines in the bone-marrow plasma of adult patients with leukemia.
Topics: Adult; Bone Marrow; Humans; Leukemia; Leukocyte Count; Putrescine; Spermidine; Spermine | 1980 |
Adenylate cyclase activity of bovine spermatozoa during maturation in the epididymis and the activation of sperm particulate adenylate cyclase by GTP and polyamines.
Topics: Adenylyl Cyclases; Animals; Cattle; Enzyme Activation; Epididymis; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Male; Polyamines; Sperm Maturation; Spermatozoa; Spermidine; Spermine | 1980 |
Rapid detection of polyamines in the sera of patients with colorectal carcinoma by liquid ion-exchange chromatography.
Topics: Aged; Cadaverine; Chromatography, Ion Exchange; Colonic Neoplasms; Female; Humans; Male; Middle Aged; Polyamines; Putrescine; Rectal Neoplasms; Spermidine; Spermine | 1980 |
Biosynthesis and accumulation of cadaverine and putrescine in rat ovary after administration of human chorionic gonadotrophin.
Topics: Animals; Cadaverine; Chorionic Gonadotropin; Diamines; Dose-Response Relationship, Drug; Female; Ovary; Putrescine; Rats; Spermidine; Spermine | 1980 |
Relation of the antiproliferative action of methylglyoxal-bis(guanylhydrazone) to the natural polyamines.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Female; Guanidines; Humans; Magnesium; Mice; Mitoguazone; Spermidine; Spermine | 1980 |
Polyamine levels in rat placenta during pregnancy.
Topics: Animals; Female; Placenta; Pregnancy; Pregnancy, Animal; Rats; Spermidine; Spermine; Time Factors | 1980 |
Effect of thioacetamide, growth hormone or partial hepatectomy on spermidine acetylase activity of rat liver cytosol.
Topics: Acetamides; Acetyltransferases; Animals; Cytosol; Growth Hormone; Hepatectomy; Liver; Male; Putrescine; Rats; Spermidine; Spermine; Thioacetamide | 1980 |
Effects of human growth hormone on blood polyamines in hypopituitarism.
Topics: Adolescent; Child; Female; Growth Hormone; Humans; Hypopituitarism; Male; Polyamines; Putrescine; Spermidine; Spermine; Time Factors | 1980 |
Increased erythrocytic spermine in Duchenne muscular dystrophy.
Topics: Child; Erythrocytes; Erythrocytes, Abnormal; Female; Hemolysis; Humans; Infant; Male; Muscular Atrophy; Muscular Diseases; Muscular Dystrophies; Myasthenia Gravis; Spermidine; Spermine | 1980 |
Acetylation of spermidine in polyamine catabolism.
Topics: Acetamides; Acetylation; Amidohydrolases; Animals; Chromatography, High Pressure Liquid; Liver; Male; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Rats; Spermidine; Spermine; Thioacetamide | 1980 |
[Possible physiological roles of polyamines at the level of the central nervous system].
Topics: Animals; Brain; Central Nervous System; Humans; Polyamines; Proteins; Rabbits; Rats; Spermidine; Spermine; Subcellular Fractions | 1980 |
Structural requirements of analogues of polyamines for migration and growth of IEC-6 cells.
Topics: Animals; Biogenic Polyamines; Cell Division; Cell Migration Inhibition; Cell Movement; Cells, Cultured; Eflornithine; Intestines; Spermidine; Spermine; Structure-Activity Relationship | 1995 |
Is polyamine decrease a common feature of apoptosis? Evidence from gamma rays- and heat shock-induced cell death.
Topics: Analysis of Variance; Animals; Apoptosis; Cell Death; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; Electrophoresis, Agar Gel; Gamma Rays; Hot Temperature; Kinetics; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Thymus Gland; Time Factors | 1995 |
Radioprotection of DNA by polyamines.
Topics: Biogenic Polyamines; Circular Dichroism; DNA; Putrescine; Radiation-Protective Agents; Spermidine; Spermine | 1995 |
Effects of polyamines on voltage-activated calcium channels in guinea-pig intestinal smooth muscle.
Topics: Action Potentials; Animals; Biogenic Polyamines; Biotransformation; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Electrophysiology; Female; Guinea Pigs; In Vitro Techniques; Microelectrodes; Muscle Contraction; Muscle, Smooth; Patch-Clamp Techniques; Putrescine; Spermidine; Spermine; Taenia | 1995 |
Polyamine metabolism in the rat liver after orthotopic liver transplantation.
Topics: Acetyltransferases; Alanine Transaminase; Animals; Aspartate Aminotransferases; DNA; Genes, myc; Graft Survival; Kinetics; L-Lactate Dehydrogenase; Liver; Liver Transplantation; Male; Malondialdehyde; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Wistar; RNA, Messenger; Spermidine; Spermine | 1995 |
Polyamines exert regulatory control on mycobacterial transcription: a study using RNA polymerase from Mycobacterium phlei.
Topics: DNA-Directed RNA Polymerases; Mycobacterium phlei; Nucleic Acid Conformation; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Putrescine; Spermidine; Spermine; Templates, Genetic; Transcription, Genetic | 1995 |
Use of 4-fluoro-L-ornithine to monitor metabolic flux through the polyamine biosynthetic pathway.
Topics: Adenosylmethionine Decarboxylase; Animals; Biogenic Polyamines; Cell Division; Cell Membrane Permeability; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Humans; Kinetics; Leukemia L1210; Melanoma; Mice; Ornithine; Ornithine Decarboxylase; Spermidine; Spermine; Tumor Cells, Cultured | 1995 |
Polyamine neurotoxicity is antagonized by dizocilpine in cultured chick cortical neurons.
Topics: Animals; Brain Ischemia; Cell Survival; Cells, Cultured; Cerebral Cortex; Chick Embryo; Dizocilpine Maleate; Ion Channels; Nervous System; Neurons; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1993 |
Erythrocyte polyamines and prognosis in stage D2 prostatic carcinoma patients.
Topics: Aged; Aged, 80 and over; Erythrocytes; Follow-Up Studies; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasm Metastasis; Neoplasm Staging; Predictive Value of Tests; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms; Spermidine; Spermine; Survival Analysis; Survival Rate | 1994 |
Uncoupling of muscle and blood platelets Ca2+ transport ATPases by heparin. Regulation by K+.
Topics: Animals; Blood Platelets; Calcium-Transporting ATPases; Glycosaminoglycans; Heparin; Kinetics; Lithium Chloride; Muscles; Osmolar Concentration; Potassium; Potassium Chloride; Rabbits; Ruthenium Red; Sarcoplasmic Reticulum; Sodium Chloride; Spermidine; Spermine | 1994 |
Polyamine transport in human promyelocytic leukemia cells and polymorphonuclear leukocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Biological Transport; Cell Line; Genistein; Gramicidin; Humans; In Vitro Techniques; Ionomycin; Isoflavones; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Neutrophils; Piperazines; Protein Kinase Inhibitors; Putrescine; Spermidine; Spermine; Sulfonamides; Temperature; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Polyamines inhibit nitric oxide synthase in rat cerebellum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cerebellum; Citrulline; Cytosol; Eflornithine; Kinetics; N-Methylaspartate; Neurons; Nitric Oxide Synthase; omega-N-Methylarginine; Polyamines; Putrescine; Rats; Spermidine; Spermine; Tritium | 1994 |
The inter-relationship between polyamines and the L-arginine nitric oxide pathway in the human placenta.
Topics: Amino Acid Oxidoreductases; Arginine; Cadaverine; Cell Line; Chorionic Villi; Female; Fetal Growth Retardation; Humans; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Placenta; Polyamines; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Third; Putrescine; Reference Values; Spermidine; Spermine | 1995 |
Inhibition of nitric oxide synthase by L-arginine metabolites.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Platelets; Cerebellum; Humans; Kinetics; Nitric Oxide Synthase; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1995 |
The activity of deoxyspergualin in multidrug-resistant cells.
Topics: Animals; Antibiotics, Antineoplastic; Cattle; Cyclosporine; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Guanidines; Horses; Humans; Membrane Proteins; Mice; Spermidine; Spermine; Tacrolimus; Tumor Cells, Cultured | 1995 |
Morphogenetic effects induced by spermine and ruthenium red in yeasts.
Topics: Cations; Cell Division; Cell Wall; Rhodotorula; Ruthenium Red; Saccharomyces cerevisiae; Schizosaccharomyces; Spermidine; Spermine | 1995 |
A photoaffinity probe for the polyamine site regulating the NMDA receptor.
Topics: Affinity Labels; Animals; Azides; Biogenic Polyamines; In Vitro Techniques; Phencyclidine; Photochemistry; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Synaptic Membranes; Synaptosomes | 1995 |
In situ substrate specificity and ultrastructural localization of polyamine oxidase activity in unfixed rat tissues.
Topics: Animals; Duodenum; Kidney; Liver; Male; Microbodies; Microscopy, Electron; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Rats; Rats, Wistar; Spermidine; Spermine; Substrate Specificity | 1995 |
Electrostatic mechanism of nucleosome spacing.
Topics: Animals; Chromatin; Detergents; Drosophila; Electrophoresis, Polyacrylamide Gel; Embryo, Nonmammalian; Histones; Magnesium; Nucleosomes; Octoxynol; Osmolar Concentration; Phosphoproteins; Phosphorylation; Polyethylene Glycols; Spermidine; Spermine | 1995 |
Intracellular polyamines mediate inward rectification of Ca(2+)-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Evoked Potentials; Hippocampus; Kainic Acid; Kinetics; Neurons; Patch-Clamp Techniques; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spermidine; Spermine; Time Factors | 1995 |
Down-regulation of ornithine decarboxylase by an increased degradation of the enzyme during gastrulation of Xenopus laevis.
Topics: Adenosylmethionine Decarboxylase; Animals; Down-Regulation; Half-Life; Ornithine Decarboxylase; Putrescine; RNA, Messenger; Spermidine; Spermine; Xenopus laevis | 1995 |
Polyamine uptake by a rodent filariid, Acanthocheilonema viteae (Nematoda: Filarioidea).
Topics: Animals; Dipetalonema; Female; Male; Muridae; Putrescine; Sex Characteristics; Spermidine; Spermine | 1995 |
Vitamin A status and metabolism of cutaneous polyamines in the hairless mouse after UV irradiation: action of beta-carotene and astaxanthin.
Topics: Animals; beta Carotene; Carotenoids; Epidermis; Female; Food, Fortified; Liver; Mice; Mice, Hairless; Neoplasms, Radiation-Induced; Nutritional Status; Ornithine Decarboxylase; Polyamines; Putrescine; Random Allocation; Skin; Skin Neoplasms; Spermidine; Spermine; Ultraviolet Rays; Vitamin A; Vitamin A Deficiency; Xanthophylls | 1995 |
Blood polyamines in the rat.
Topics: Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Erythrocytes; Frontal Lobe; Male; Putrescine; Rats; Rats, Wistar; Regression Analysis; Spectrometry, Fluorescence; Spermidine; Spermine | 1995 |
Polyamines promote regeneration of injured axons of cultured rat hippocampal neurons.
Topics: Animals; Axons; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Hippocampus; Nerve Regeneration; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine | 1995 |
Specific depletion of spermidine and spermine in HTC cells treated with inhibitors of aminopropyltransferases.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Cyclohexylamines; Kinetics; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Rats; Spermidine; Spermidine Synthase; Spermine; Spermine Synthase; Time Factors; Tumor Cells, Cultured | 1995 |
Polyamine effects on purine-purine-pyrimidine triple helix formation by phosphodiester and phosphorothioate oligodeoxyribonucleotides.
Topics: Base Sequence; Kinetics; Magnesium; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Organophosphates; Polyamines; Potassium; Purines; Putrescine; Pyrimidines; Spermidine; Spermine; Thionucleotides | 1995 |
Polyamines as endogenous modulators of the N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Putrescine; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1995 |
Polyamines in cow's and sow's milk.
Topics: Age Factors; Animals; Cattle; Fatty Acids; Female; Lactation; Milk; Polyamines; Proteins; Spermidine; Spermine; Swine | 1995 |
Polyamines in human brain: regional distribution and influence of aging.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Brain; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Male; Middle Aged; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Tissue Distribution | 1995 |
Putrescine level in blood from the rat portal vein is influenced by inhibition of diamine oxidase.
Topics: Amine Oxidase (Copper-Containing); Animals; Female; Guanidines; Portal Vein; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine | 1995 |
Switching between control and phytohaemagglutinin-containing diets affects growth of Krebs II ascites cells and produces differences in the levels of putrescine, spermidine and spermine.
Topics: Animals; Carcinoma, Krebs 2; Cell Count; Cell Division; Diet; Female; Humans; Hypertrophy; Intestine, Small; Mice; Mice, Inbred Strains; Phytohemagglutinins; Putrescine; Spermidine; Spermine | 1995 |
Release of spermidine from the rat cortex following permanent middle cerebral artery occlusion.
Topics: Animals; Brain Ischemia; Cerebral Arteries; Cerebral Cortex; Chromatography, High Pressure Liquid; Extracellular Space; Male; Microdialysis; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Time Factors | 1995 |
The importance of dietary polyamines in cell regeneration and growth.
Topics: Adult; Amine Oxidase (Copper-Containing); Amino Acids; Animals; Cell Division; Cheese; Fruit; Growth; Humans; Intestinal Absorption; Meat; Nutritional Requirements; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Vegetables | 1995 |
Biochemical and growth-modulatory effects of the new S-adenosylmethionine decarboxylase inhibitor CGP 48664 in malignant and immortalized normal human breast epithelial cells in culture.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Amidines; Breast; Breast Neoplasms; Cell Division; Cell Line, Transformed; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Indans; Neoplasms, Hormone-Dependent; Ornithine Decarboxylase; Spermidine; Spermine; Tumor Cells, Cultured | 1995 |
Improved method for polyamine determination in TMV, a rod-shaped virus.
Topics: Chromatography, High Pressure Liquid; Perchlorates; Polyamines; Putrescine; Spermidine; Spermine; Tobacco Mosaic Virus | 1995 |
Spermine induces haemoglobin synthesis in murine erythroleukaemia cells.
Topics: Acetamides; Animals; Cell Cycle; Cell Division; Cell Size; Erythropoiesis; Globins; Hemoglobins; Leukemia, Erythroblastic, Acute; Mice; Putrescine; RNA, Messenger; Spermidine; Spermine; Tumor Cells, Cultured | 1995 |
Treatment of nude mice with 4-amidinoindan -1- one2 '- amidinohydrazone, a new S-adenosylmethionine decarboxylase inhibitor, delays growth and inhibits metastasis of human melanoma cells.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Cell Division; Culture Media; Dose-Response Relationship, Drug; Humans; Indans; Lung Neoplasms; Male; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Spermidine; Spermine; Tumor Cells, Cultured | 1995 |
[Polyamine system in experimental retinopathy of prematurity].
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Humans; Hyperoxia; Infant, Newborn; Lens, Crystalline; Ornithine Decarboxylase; Rats; Rats, Wistar; Retina; Retinopathy of Prematurity; Spermidine; Spermine | 1995 |
Inward rectification of both AMPA and kainate subtype glutamate receptors generated by polyamine-mediated ion channel block.
Topics: Calcium; Cell Line, Transformed; Glutamic Acid; Humans; Intracellular Fluid; Ion Channel Gating; Kainic Acid; Kidney; Magnesium; Membrane Potentials; Patch-Clamp Techniques; Putrescine; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Fusion Proteins; Spermidine; Spermine; Transfection | 1995 |
Transglutaminase activity in enterocytes isolated from pig jejunum.
Topics: Animals; Arginine; Calcium; Cell Separation; Glutamine; Glycine; Jejunum; Kinetics; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Swine; Temperature; Transglutaminases | 1995 |
Polyamines may increase the percentage of in-vitro fertilized murine oocytes that develop into blastocysts.
Topics: Animals; Blastocyst; Culture Media; Embryo Implantation; Female; Fertilization in Vitro; Growth Substances; In Vitro Techniques; Male; Mice; Oocytes; Polyamines; Putrescine; Spermidine; Spermine | 1995 |
Ehrlich ascites tumour cells have a more active mitochondrial polyamine transporter than that of rat liver.
Topics: Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Carrier Proteins; Cations, Monovalent; Kinetics; Magnesium; Male; Mice; Mice, Inbred ICR; Mitochondria; Mitochondria, Liver; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine | 1995 |
Interactions of polyamines with Mg(2+)-sensitive macroelectrodes and Mg2+ buffers.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Citrates; Citric Acid; Ion-Selective Electrodes; Magnesium; Polyamines; Putrescine; Spermidine; Spermine | 1995 |
Polyamines and prostatic carcinoma: clinical and therapeutic implications.
Topics: Adult; Aged; Animals; Biomarkers, Tumor; Cell Division; Cell Transformation, Neoplastic; Eflornithine; Erythrocyte Count; Erythrocytes; Follow-Up Studies; Humans; Male; Mice; Middle Aged; Models, Biological; Neoplasm Staging; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms; Spermidine; Spermine | 1993 |
Effect of polyphosphates on the activity of amine oxidases.
Topics: Amine Oxidase (Copper-Containing); Animals; Cattle; Enzyme Activation; Glycine max; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Polyphosphates; Spermidine; Spermine | 1995 |
Ornithine decarboxylase activity and polyamine concentrations in fetal rat brain: response to chronic hypoxic-hypoxia and/or carbon monoxide-hypoxia.
Topics: Animals; Animals, Newborn; Brain; Carbon Monoxide; Embryonic and Fetal Development; Female; Gestational Age; Hypoxia; Ornithine Decarboxylase; Polyamines; Pregnancy; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine | 1994 |
Polyamine metabolism in human hepatocellular cancer cells (Hep-G2).
Topics: Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; DNA, Neoplasm; Eflornithine; Humans; Liver Neoplasms; Polyamines; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1994 |
An investigation of the mechanism of polyamine efflux from human colorectal carcinoma cells.
Topics: Cell Line; Colorectal Neoplasms; Humans; Kinetics; Polyamines; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1994 |
Differential effects of tumor and parenteral nutrition on jejunal mucosal polyamines.
Topics: Adenosylmethionine Decarboxylase; Animals; Intestinal Mucosa; Jejunum; Male; Neoplasm Transplantation; Ornithine Decarboxylase; Parenteral Nutrition, Total; Polyamines; Proteins; Putrescine; Rats; Rats, Inbred F344; Sarcoma, Experimental; Spermidine; Spermine; Weight Gain | 1995 |
Alterations in polyamine levels of nematode, earthworm, leech and planarian during regeneration, temperature and osmotic stresses.
Topics: Animals; Anisakis; Ascaris suum; Caenorhabditis elegans; Dirofilaria immitis; Leeches; Nematoda; Oligochaeta; Osmotic Pressure; Planarians; Polyamines; Putrescine; Regeneration; Spermidine; Spermine; Temperature | 1995 |
Comodulation of cellular polyamines and proliferation: biomarker application to colorectal mucosa.
Topics: Biomarkers; Cell Division; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Colon; Colonic Neoplasms; Deoxycholic Acid; Epithelium; Humans; Intestinal Mucosa; Kinetics; Pneumatosis Cystoides Intestinalis; Polyamines; Rectum; Spermidine; Spermine; Vitamin A | 1995 |
Significance of urinary N1,N8-diacetylspermidine and N1,N12-diacetylspermine as indicators of neoplastic diseases.
Topics: Adult; Female; Humans; Male; Middle Aged; Neoplasms; Spermidine; Spermine | 1995 |
B lymphocytes with latent EBV infection appearing in long-term bone marrow cultures (HLTBMCs) from haematological patients induce lysis of stromal microenvironment.
Topics: B-Lymphocytes; Bone Marrow; Cell Line, Transformed; Cell Transformation, Viral; Erythroid Precursor Cells; Hematologic Diseases; Herpesvirus 4, Human; Humans; Receptors, Complement 3d; Receptors, Virus; Spermidine; Spermine; Tumor Cells, Cultured; Virus Latency | 1995 |
Determination of amounts of polyamines excreted in urine: demonstration of N1,N8-diacetylspermidine and N1,N12-diacetylspermine as components commonly occurring in normal human urine.
Topics: Biogenic Polyamines; Biomarkers; Chemical Fractionation; Humans; Reference Values; Spermidine; Spermine | 1995 |
Inhibition of the growth of various human and mouse tumor cells by 1,15-bis(ethylamino)-4,8,12-triazapentadecane.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Line; Colonic Neoplasms; Growth Inhibitors; Humans; Kinetics; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured | 1995 |
Polyamines alter sequence-specific DNA-protein interactions.
Topics: Base Sequence; Cobalt; DNA; DNA-Binding Proteins; HeLa Cells; Herpesvirus 1, Human; Humans; Immediate-Early Proteins; Kinetics; Molecular Sequence Data; Oligodeoxyribonucleotides; Polyamines; Protein Binding; Putrescine; Radiation-Sensitizing Agents; Spermidine; Spermine; Substrate Specificity | 1995 |
Biogenic amines and microbial quality of sprouts.
Topics: Agmatine; Biogenic Amines; Cadaverine; Fabaceae; Food Microbiology; Histamine; Plants, Medicinal; Polyamines; Putrescine; Species Specificity; Spermidine; Spermine | 1995 |
Saccharomyces boulardii enhances rat intestinal enzyme expression by endoluminal release of polyamines.
Topics: alpha-Glucosidases; Animals; Gene Expression; Humans; Ileum; Intestinal Mucosa; Jejunum; Polyamines; Putrescine; Rats; Rats, Wistar; Reference Values; Saccharomyces; Spermidine; Spermine; Sucrase | 1994 |
Pattern of polyamines and related monoacetyl derivatives in chick embryo retina during development.
Topics: Animals; Biogenic Polyamines; Cell Differentiation; Cell Division; Chick Embryo; gamma-Aminobutyric Acid; Putrescine; Retina; Spermidine; Spermine | 1994 |
Nitric oxide effects on polyamine pathways in cultured hepatocytes.
Topics: Cell Line; Humans; Kinetics; Liver; Nitric Oxide; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine | 1994 |
Hormonal and feedback regulation of putrescine and spermidine transport in human breast cancer cells.
Topics: Biological Transport; Breast Neoplasms; Cell Division; Cell Line; Cycloheximide; Drug Synergism; Eflornithine; Estradiol; Feedback; Humans; Insulin; Kinetics; Putrescine; Spermidine; Spermine; Tretinoin; Tumor Cells, Cultured | 1995 |
Role of polyamines in the membrane pathology of schizophrenia. A study using fibroblasts from schizophrenic patients and normal controls.
Topics: Adult; Cell Division; Cell Membrane; Culture Techniques; Female; Fibroblasts; Humans; Male; Middle Aged; Polyamines; Putrescine; Reference Values; Schizophrenia; Schizophrenic Psychology; Spermidine; Spermine | 1994 |
Effects of metal treatment on DNA repair in polyamine-depleted HeLa cells with special reference to nickel.
Topics: DNA Repair; Eflornithine; HeLa Cells; Humans; Metals; Nickel; Putrescine; Spermidine; Spermine | 1994 |
Inhibition of mitochondrial permeability transition by polyamines and magnesium: importance of the number and distribution of electric charges.
Topics: Animals; Calcium; Hydrogen-Ion Concentration; Intracellular Membranes; Magnesium; Membrane Potentials; Mitochondria, Liver; Permeability; Phosphates; Polyamines; Putrescine; Rats; Spermidine; Spermine; Structure-Activity Relationship | 1995 |
Diamine-oxidase activity and tissue di- and poly-amine contents of human ovarian, cervical and endometrial carcinoma.
Topics: Adult; Amine Oxidase (Copper-Containing); Biogenic Polyamines; Cadaverine; Diamines; Endometrial Neoplasms; Female; Histamine; Humans; Middle Aged; Ovarian Neoplasms; Putrescine; Reference Values; Spermidine; Spermine; Uterine Cervical Neoplasms | 1995 |
Role of polyamines in hypertension induced by angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Cardiomegaly; Disease Models, Animal; Heart Ventricles; Hypertension; Liver; Male; Mesenteric Arteries; Myocardium; Polyamines; Putrescine; Rats; Rats, Inbred WKY; Spermidine; Spermine | 1995 |
Regulation of N-methyl-D-aspartate receptor-mediated calcium transport and norepinephrine release in rat hippocampus synaptosomes by polyamines.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biological Transport; Calcium; Eflornithine; Egtazic Acid; Female; Hippocampus; Kinetics; N-Methylaspartate; Norepinephrine; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Synaptosomes | 1994 |
[3H]CGP 39653 binding to the agonist site of the N-methyl-D-aspartate receptor is modulated by Mg2+ and polyamines independently of the arcaine-sensitive polyamine site.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biguanides; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Glycine; Kinetics; Magnesium; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Tritium | 1994 |
Regulation of transglutaminase activity by polyamines in the gastrointestinal mucosa of rats.
Topics: Animals; Chromatography, High Pressure Liquid; Duodenum; Eflornithine; Gastric Mucosa; Intestinal Mucosa; Kinetics; Male; Ornithine Decarboxylase; Parietal Cells, Gastric; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Time Factors; Transglutaminases | 1994 |
Effect of polyamines on glutamate dehydrogenase within permeabilized kidney-cortex mitochondria and isolated renal tubules of rabbit.
Topics: Animals; Biogenic Polyamines; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Kidney Cortex; Kidney Tubules; Male; Mitochondria; Putrescine; Rabbits; Spermidine; Spermine | 1994 |
The presence of an active S-adenosylmethionine decarboxylase gene increases the growth defect observed in Saccharomyces cerevisiae mutants unable to synthesize putrescine, spermidine, and spermine.
Topics: Adenosylmethionine Decarboxylase; Genes, Fungal; Ornithine Decarboxylase; Polyamines; Putrescine; Saccharomyces cerevisiae; Spermidine; Spermine | 1994 |
Regulation of the phosphoinositide cascade by polyamines in brain.
Topics: Agmatine; Animals; Biguanides; Calcium; Cell Membrane; Cerebral Cortex; Deoxycholic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Homeostasis; Kinetics; Male; Phosphatidylinositols; Polyamines; Rats; Spermidine; Spermine | 1994 |
Antiproliferative properties of polyamine analogues: a structure-activity study.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Binding, Competitive; Cell Division; Leukemia L1210; Mice; Molecular Structure; Ornithine Decarboxylase Inhibitors; Polyamines; Spermidine; Spermine; Structure-Activity Relationship | 1994 |
Polyamines block Ca(2+)-activated K+ channels in pituitary tumor cells (GH3).
Topics: Animals; Calcium; Electric Conductivity; Membrane Potentials; Pituitary Neoplasms; Polyamines; Potassium Channel Blockers; Putrescine; Rats; Spermidine; Spermine; Tumor Cells, Cultured | 1994 |
Effects of the S-adenosylmethionine decarboxylase inhibitor, 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine, on cell growth and polyamine metabolism and transport in Chinese hamster ovary cell cultures.
Topics: Adenosylmethionine Decarboxylase; Animals; Biological Transport; Cell Division; CHO Cells; Cricetinae; Cycloheximide; Deoxyadenosines; Eflornithine; Kinetics; Polyamines; Putrescine; Spermidine; Spermine | 1994 |
Polyamines regulate human medullary thyroid carcinoma TT-cell proliferation and secretion of calcitonin and calcitonin gene-related peptide.
Topics: Adenosylmethionine Decarboxylase; Calcitonin; Calcitonin Gene-Related Peptide; Carcinoma, Medullary; Cell Division; Eflornithine; Humans; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine; Thyroid Neoplasms; Tumor Cells, Cultured | 1994 |
Modulation of ornithine decarboxylase activity by prolactin in seminal vesicles of the rat.
Topics: Animals; Liver; Male; Organ Size; Ornithine Decarboxylase; Pituitary Neoplasms; Polyamines; Prolactin; Prolactinoma; Putrescine; Rats; Rats, Inbred BUF; Reference Values; Seminal Vesicles; Spermidine; Spermine | 1994 |
Antiproliferative effects of inhibitors of deoxyhypusine synthase. Inhibition of growth of Chinese hamster ovary cells by guanyl diamines.
Topics: Animals; Cell Division; Cell Survival; CHO Cells; Cricetinae; Diamines; Dose-Response Relationship, Drug; Guanine; Indicators and Reagents; Kinetics; Lysine; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Protein Biosynthesis; Putrescine; Spermidine; Spermine; Structure-Activity Relationship | 1994 |
Autoradiographic distribution and characteristics of high- and low-affinity polyamine-sensitive [3H]ifenprodil sites in the rat brain: possible relationship to NMDAR2B receptors and calmodulin.
Topics: Animals; Autoradiography; Binding, Competitive; Brain; Calmodulin; Hippocampus; Imidazoles; Male; Piperidines; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sepharose; Spermidine; Spermine; Sulfonamides; Tissue Distribution; Trifluoperazine; Tritium | 1994 |
Spermine and spermidine as gating molecules for inward rectifier K+ channels.
Topics: Animals; Diamines; Ion Channel Gating; Magnesium; Membrane Potentials; Mutagenesis; Oocytes; Patch-Clamp Techniques; Potassium Channels; Putrescine; Spermidine; Spermine; Xenopus | 1994 |
The role of hypusine depletion in cytostasis induced by S-adenosyl-L-methionine decarboxylase inhibition: new evidence provided by 1-methylspermidine and 1,12-dimethylspermine.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Deoxyadenosines; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Leukemia L1210; Lysine; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; RNA-Binding Proteins; Spermidine; Spermine; Substrate Specificity; Tumor Cells, Cultured | 1994 |
Chronic neonatal blockade of NMDA receptor does not affect developmental polyamine metabolism but results in altered response to the excitotoxic induction of ornithine decarboxylase.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Brain; Cerebellum; Cerebral Cortex; Enzyme Induction; Hippocampus; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reference Values; Spermidine; Spermine; Telencephalon | 1994 |
Effects of transient expression of spermidine/spermine N1-acetyltransferase in COS cells.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Cell Line; Gene Expression; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine; Transfection | 1994 |
A group of chromosomal proteins is specifically released by spermine and loses DNA-binding activity upon phosphorylation.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Cell Nucleus; Chromatin; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Endopeptidases; High Mobility Group Proteins; Histones; Immunoblotting; Molecular Sequence Data; Nuclear Proteins; Oryza; Peptide Fragments; Phosphorylation; Putrescine; Sequence Homology, Amino Acid; Spermidine; Spermine | 1994 |
Polyamines promote neurite elongation of cultured rat hippocampal neurons.
Topics: Animals; Axons; Biogenic Polyamines; Cell Survival; Cells, Cultured; Hippocampus; Neurites; Neurons; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine | 1994 |
Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: therapeutic implications.
Topics: Breast Neoplasms; Cell Division; Cell Line; Eflornithine; Estradiol; Female; Flow Cytometry; G1 Phase; Gene Expression; Humans; Kinetics; Ornithine Decarboxylase; Polyamines; Putrescine; RNA, Messenger; Spermidine; Spermine; Structure-Activity Relationship; Thymidine; Time Factors; Tumor Cells, Cultured | 1994 |
Synergism between the NMDA receptor antagonistic effects of ifenprodil and the glycine antagonist, 7-chlorokynurenate, in vivo.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Synergism; Glycine; Injections; Kynurenic Acid; Male; N-Methylaspartate; Neostriatum; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1994 |
N-(3-aminopropyl)-cyclohexylamine blocks facilitation by spermidine of N-methyl-DL-aspartate-induced seizure in mice in vivo.
Topics: Animals; Cyclohexylamines; Drug Interactions; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Putrescine; Seizures; Serine; Spermidine; Spermine | 1994 |
Cochlear polyamines: markers of otitis media-induced cochlear damage.
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Cochlea; Cochlear Duct; Cochlear Nerve; Guinea Pigs; Organ of Corti; Otitis Media; Pneumococcal Infections; Putrescine; Spermidine; Spermine; Stria Vascularis | 1994 |
Stimulation of phospholipase A2 activity in mitochondria by magnesium and polyamines.
Topics: Animals; Cations, Divalent; Enzyme Activation; Kinetics; Magnesium; Mitochondria, Liver; Phospholipases A; Phospholipases A2; Rats; Spermidine; Spermine | 1994 |
Human leukemic pre-B line (KM-3) treated with phorbol-ester: trend of polyamines during cell differentiation.
Topics: B-Lymphocytes; Cell Cycle; Cell Differentiation; Humans; Leukemia, Lymphoid; Putrescine; Regression Analysis; S Phase; Spermidine; Spermine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Involvement of polyamines in epidermal growth factor (EGF), transforming growth factor (TGF)-alpha and -beta 1 action on culture of L6 and fetal bovine myoblasts.
Topics: Adenosylmethionine Decarboxylase; Animals; Cattle; Cell Line; Cells, Cultured; Eflornithine; Epidermal Growth Factor; Humans; Muscles; Ornithine Decarboxylase; Polyamines; Protein Biosynthesis; Rats; Signal Transduction; Spermidine; Spermine; Transforming Growth Factor alpha; Transforming Growth Factor beta | 1994 |
[The determination of polyamines in tumors of the maxillofacial area].
Topics: Carcinoma; Chromatography, High Pressure Liquid; Facial Neoplasms; Humans; Jaw Neoplasms; Parotid Neoplasms; Polyamines; Putrescine; Sensitivity and Specificity; Spermidine; Spermine | 1994 |
Evolution of biochemical parameters characterizing the proximal small intestine after orally administered spermine in unweaned rats.
Topics: Administration, Oral; alpha-Glucosidases; Animals; Animals, Suckling; beta-Galactosidase; DNA; Dose-Response Relationship, Drug; Female; Intestine, Small; Lactase; Male; Microvilli; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Sucrase | 1993 |
Characterization of polyamine transport in rat aortic smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Binding, Competitive; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Eflornithine; Kinetics; Muscle, Smooth, Vascular; Paraquat; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine | 1994 |
Polyamine inhibition of transbilayer movement of plasma membrane phospholipids in the erythrocyte ghost.
Topics: 4-Chloro-7-nitrobenzofurazan; Calcium; Erythrocyte Membrane; Hemolysis; Humans; Hypotonic Solutions; Kinetics; Lipid Bilayers; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Polyamines; Putrescine; Spermidine; Spermine | 1994 |
Kainate-induced seizure activity stimulates the polyamine interconversion pathway in rat brain.
Topics: Acetylation; Acetyltransferases; Animals; Biogenic Polyamines; Brain; Brain Chemistry; Kainic Acid; Male; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Rats; Rats, Sprague-Dawley; Seizures; Spermidine; Spermine | 1994 |
Polyamine-induced changes in the sedimentation profile and DNA binding of aryl hydrocarbon receptor.
Topics: Binding Sites; Centrifugation, Density Gradient; DNA; Dose-Response Relationship, Drug; Humans; Polyamines; Polychlorinated Dibenzodioxins; Putrescine; Receptors, Aryl Hydrocarbon; Ribonucleases; Spermidine; Spermine; Tumor Cells, Cultured | 1994 |
Antizyme protects against abnormal accumulation and toxicity of polyamines in ornithine decarboxylase-overproducing cells.
Topics: Animals; Base Sequence; Cell Division; Cell Line; DNA Primers; Gene Expression; Mice; Molecular Sequence Data; Ornithine Decarboxylase Inhibitors; Polyamines; Proteins; RNA, Messenger; Spermidine; Spermine; Transfection | 1994 |
Differences in the post-translational modification of proteins by polyamines between weakly and highly metastatic B16 melanoma cells.
Topics: Animals; Melanins; Melanoma, Experimental; Mice; Neoplasm Metastasis; Neoplasm Proteins; Putrescine; Spermidine; Spermine; Theophylline; Transglutaminases | 1993 |
Induction of ornithine decarboxylase by N-methyl-D-aspartate receptor activation is unrelated to potentiation of glutamate excitotoxicity by polyamines in cerebellar granule neurons.
Topics: Animals; Cell Death; Cells, Cultured; Cerebellum; Drug Synergism; Eflornithine; Enzyme Induction; Glutamates; Glutamic Acid; Neurons; Ornithine Decarboxylase; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Spermidine; Spermine | 1993 |
Inhibition of calcium signalling in murine splenocytes by polyamines: differential effects on CD4 and CD8 T-cells.
Topics: Animals; Calcium; CD4-Positive T-Lymphocytes; Concanavalin A; Ionomycin; Mice; Mice, Inbred BALB C; Polyamines; Putrescine; Signal Transduction; Spermidine; Spermine; Spleen; T-Lymphocytes, Regulatory | 1993 |
[The effect of chemically modified polyamine analogs on polyamine and putrescine biosynthesis in a cell-free test system from a rat hepatoma].
Topics: Animals; Antineoplastic Agents; Biogenic Polyamines; Cell-Free System; Eflornithine; Liver Neoplasms, Experimental; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine; Structure-Activity Relationship | 1993 |
Estrogen receptors and polyamine levels in human gastric carcinoma.
Topics: Adenocarcinoma; Biogenic Polyamines; Female; Gastric Mucosa; Humans; Male; Middle Aged; Putrescine; Receptors, Estrogen; Spermidine; Spermine; Stomach Neoplasms | 1994 |
HPLC and NMR investigation of the serum amine oxidase catalyzed oxidation of polyamines.
Topics: Acrolein; Aldehydes; Amine Oxidase (Copper-Containing); Animals; Borohydrides; Catalysis; Cattle; Chromatography, High Pressure Liquid; Fetal Blood; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Propylamines; Putrescine; Spectrometry, Mass, Fast Atom Bombardment; Spermidine; Spermine | 1994 |
Polyamines modulate [3H]L-689,560 binding to the glycine site of the NMDA receptor from rat brain.
Topics: Aminoquinolines; Animals; Biguanides; Binding, Competitive; Cerebral Cortex; Diamines; Dose-Response Relationship, Drug; Glycine; Hippocampus; Polyamines; Putrescine; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1994 |
Gender-related differences in the inhibitory effect on liver regeneration in alcohol-treated rats: study of polyamine metabolism.
Topics: Acetyltransferases; Animals; Ethanol; Female; Hepatectomy; Liver; Liver Regeneration; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Sex Characteristics; Sex Factors; Spermidine; Spermine | 1993 |
Increased spermidine or spermine level is essential for hepatocyte growth factor-induced DNA synthesis in cultured rat hepatocytes.
Topics: Adenosylmethionine Decarboxylase; Animals; Cells, Cultured; DNA; Eflornithine; Hepatocyte Growth Factor; Liver; Male; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Rats; Rats, Wistar; Spermidine; Spermine | 1994 |
Postnatal changes in cochlear polyamine metabolism in the rat.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cochlea; Eflornithine; Female; Organ of Corti; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Pregnancy; Putrescine; Rats; Spermidine; Spermine | 1994 |
Polyamine potentiation and inhibition of NMDA-mediated increases of intracellular free Ca2+ in cultured chick cortical neurons.
Topics: Animals; Biogenic Polyamines; Calcium; Cells, Cultured; Cerebral Cortex; Chick Embryo; Chromatography, High Pressure Liquid; Fura-2; Ion Transport; N-Methylaspartate; Neurons; Polyamines; Putrescine; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1994 |
Characterization of a COS cell line deficient in polyamine transport.
Topics: Animals; Biological Transport; Cell Division; Cell Line; Cloning, Molecular; Culture Media; Mitoguazone; Plasmids; Polyamines; Putrescine; Spermidine; Spermine; Transfection | 1994 |
Selective putrescine export is regulated by insulin and ornithine in Reuber H35 hepatoma cells.
Topics: Animals; Biological Transport; Culture Media; Insulin; Liver Neoplasms, Experimental; Ornithine; Putrescine; Rats; Spermidine; Spermine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Verapamil | 1994 |
Expression of protooncogenes c-fos and c-myc in healing of gastric mucosal stress ulcers.
Topics: Animals; Blotting, Northern; Blotting, Western; DNA; DNA Probes; Eflornithine; Enzyme Induction; Gastric Mucosa; Gene Expression; Genes, fos; Genes, myc; Immersion; Kinetics; Male; Ornithine Decarboxylase; Parietal Cells, Gastric; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Putrescine; Rats; Rats, Sprague-Dawley; Restraint, Physical; RNA, Messenger; Spermidine; Spermine; Stomach Ulcer; Stress, Psychological; Thymidine; Time Factors; Wound Healing | 1994 |
Change of polyamine level in various tissues of male rats intoxicated with paraquat.
Topics: Animals; Chromatography, High Pressure Liquid; Male; Paraquat; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Tissue Distribution | 1993 |
Interference of PCR amplification by the polyamines, spermine and spermidine.
Topics: Artifacts; Base Sequence; DNA; DNA Primers; DNA-Directed DNA Polymerase; Electrophoresis, Agar Gel; Formamides; Hordeum; Indicators and Reagents; Molecular Sequence Data; Polymerase Chain Reaction; Spermidine; Spermine; Taq Polymerase | 1993 |
Determination of free polyamines in human bile by high-performance liquid chromatography.
Topics: Bile; Cadaverine; Cholelithiasis; Chromatography, High Pressure Liquid; Humans; Polyamines; Putrescine; Spermidine; Spermine | 1993 |
Correlation between the inhibition of cell growth by accumulated polyamines and the decrease of magnesium and ATP.
Topics: Adenosine Triphosphate; Animals; Cell Division; Kinetics; Magnesium; Mammary Neoplasms, Experimental; Mice; Microscopy, Electron; Polyamines; Spermidine; Spermine; Tumor Cells, Cultured | 1993 |
Selenium and difluoromethylornithine additively inhibit DMH-induced distal colon tumor formation in rats fed a fiber-free diet.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colon; Colonic Neoplasms; Diet; Dietary Fiber; Dimethylhydrazines; Drug Interactions; Eflornithine; Liver; Male; Ornithine Decarboxylase; Putrescine; Rats; Rats, Sprague-Dawley; Reference Values; S-Adenosylmethionine; Selenium; Spermidine; Spermine | 1993 |
Radiosensitivity of polyamine-depleted HeLa cells and modulation by the aminothiol WR-1065.
Topics: Cell Survival; Clone Cells; Deoxyadenosines; DNA Damage; Dose-Response Relationship, Radiation; Eflornithine; HeLa Cells; Humans; Kinetics; Mercaptoethylamines; Mitoguazone; Polyamines; Putrescine; Radiation-Protective Agents; Spermidine; Spermine; Time Factors; Tumor Stem Cell Assay; X-Rays | 1994 |
Complexes of the polyamines spermine, spermidine and putrescine with alpha-lactalbumins.
Topics: Amino Acid Sequence; Animals; Circular Dichroism; Humans; Lactalbumin; Molecular Sequence Data; Protein Denaturation; Putrescine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spermidine; Spermine; Thermodynamics | 1993 |
Acute and chronic hyperbaric oxygen exposure in humans: effects on blood polyamines, adrenocorticotropin and beta-endorphin.
Topics: Adrenocorticotropic Hormone; Adult; beta-Endorphin; Diving; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Polyamines; Spermidine; Spermine; Time Factors | 1993 |
The inhibition of the inositol 1,4,5-trisphosphate receptor from rat cerebellum by spermine and other polyamines.
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels; Cerebellum; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Microsomes; Neomycin; Polyamines; Putrescine; Rats; Receptors, Cytoplasmic and Nuclear; Spermidine; Spermine | 1993 |
TGF-beta 1 inhibits polyamine biosynthesis in K 562 leukemic cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosylmethionine Decarboxylase; Apoptosis; Cell Division; Cell Line; Dose-Response Relationship, Drug; Eflornithine; Humans; Isoquinolines; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mitoguazone; Ornithine Decarboxylase; Piperazines; Polyamines; Protein Kinase Inhibitors; Putrescine; Spermidine; Spermine; Transforming Growth Factor beta; Tumor Cells, Cultured | 1993 |
Alterations in membrane permeability induced by aminoglycoside antibiotics: studies on liposomes and cultured cells.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Calcium; Cells, Cultured; Cytosol; Fluoresceins; Fluorescence Polarization; Liposomes; Macrophages; Manganese; Membrane Fluidity; Membranes; Mice; Molecular Conformation; Permeability; Spermidine; Spermine; Tumor Cells, Cultured | 1993 |
Characteristics of phospholipase C present in membranes of Xenopus laevis oocytes. Stimulation by phosphatidic acid.
Topics: Animals; Calcium; Cell Membrane; Chromatography, High Pressure Liquid; Female; Hydrolysis; Oocytes; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipids; Polylysine; Spermidine; Spermine; Type C Phospholipases; Xenopus laevis | 1993 |
The involvement of polyamines in the activation of vitamin D receptor from porcine intestinal mucosa.
Topics: Animals; Calcitriol; Centrifugation, Density Gradient; Cytosol; DNA-Binding Proteins; Female; Intestinal Mucosa; Kinetics; Polyamines; Putrescine; Receptors, Calcitriol; Spermidine; Spermine; Structure-Activity Relationship; Swine | 1994 |
Assay of the polyamine spermine by a monoclonal antibody-based ELISA.
Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Antibody Specificity; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Hybridomas; Mice; Mice, Inbred BALB C; Ovalbumin; Serum Albumin; Spermidine; Spermine; Triticum | 1993 |
Polyamine-mediated regulation of S-adenosylmethionine decarboxylase expression in mammalian cells. Studies using 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine, a suicide inhibitor of the enzyme.
Topics: Adenosylmethionine Decarboxylase; Animals; Deoxyadenosines; Enzyme Precursors; Gene Expression Regulation, Enzymologic; Leukemia L1210; Mice; Polyamines; Protein Processing, Post-Translational; Putrescine; Spermidine; Spermine | 1993 |
Acetylpolyamines decrease blood pressure, [Ca++]i and isometric force of vascular smooth muscle.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Calcium; Depression, Chemical; Hypotension; In Vitro Techniques; Intracellular Fluid; Isometric Contraction; Male; Muscle, Smooth, Vascular; Polyamines; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Tail | 1993 |
Effects of polyamines on intracellular calcium and mechanical activity in smooth muscle of guinea-pig taenia coli.
Topics: Action Potentials; Animals; Calcium; Cell Membrane; Colon; Dose-Response Relationship, Drug; Female; Fura-2; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Polyamines; Potassium; Potassium Chloride; Putrescine; Spermidine; Spermine | 1993 |
Polyamines as negative regulators of casein kinase-2: the phosphorylation of calmodulin triggered by polylysine and by the alpha[66-86] peptide is prevented by spermine.
Topics: Amino Acid Sequence; Animals; Calmodulin; Casein Kinases; Cytosol; Dose-Response Relationship, Drug; Kinetics; Liver; Macromolecular Substances; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Polyamines; Polylysine; Protein Kinase Inhibitors; Protein Kinases; Putrescine; Rats; Spermidine; Spermine; Substrate Specificity | 1993 |
Transgenic mice over-expressing the human spermidine synthase gene.
Topics: Animals; Base Sequence; Cloning, Molecular; DNA, Single-Stranded; Female; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Transgenic; Molecular Sequence Data; Polymerase Chain Reaction; Putrescine; Spermidine; Spermidine Synthase; Spermine | 1993 |
Polyamines, diamine oxidase, and ornithine decarboxylase activity in colorectal cancer and in normal surrounding mucosa.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amine Oxidase (Copper-Containing); Biomarkers, Tumor; Carcinoembryonic Antigen; Colon; Colonic Neoplasms; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Neoplasm Staging; Ornithine Decarboxylase; Polyamines; Putrescine; Rectal Neoplasms; Rectum; Spermidine; Spermine | 1993 |
Interaction of a polyamine analogue, 1,19-bis-(ethylamino)-5,10,15- triazanonadecane (BE-4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines.
Topics: Brain Neoplasms; Cell Division; Cell Survival; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1993 |
Transport of the immunosuppressant 15-deoxyspergualin in human peripheral blood lymphocytes.
Topics: Biological Transport; Cell Nucleus; Cells, Cultured; Cytosol; Guanidines; Humans; Immunosuppressive Agents; Kinetics; Lymphocytes; Putrescine; Spermidine; Spermine; Subcellular Fractions; Tritium | 1993 |
Toxicological studies with primary cultures of chick embryo cells: DNA fragmentation under the influence of DNase I-inhibitors.
Topics: Animals; Brain; Cations, Divalent; Cell Nucleus; Cells, Cultured; Chemical Phenomena; Chemistry, Physical; Chick Embryo; Chromatin; Deoxyribonuclease I; DNA; Egtazic Acid; Intercalating Agents; Novobiocin; Spermidine; Spermine; Suramin; Ultraviolet Rays; Viscosity; X-Rays | 1993 |
The diversity of Na(+)-independent uptake systems for polyamines in rat intestinal brush-border membrane vesicles.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Dose-Response Relationship, Drug; Intestine, Small; Kinetics; Male; Microvilli; Polyamines; Potassium; Putrescine; Rats; Rats, Wistar; Sodium; Spermidine; Spermine; Valinomycin | 1993 |
Characterisation of [3H]gabapentin binding to a novel site in rat brain: homogenate binding studies.
Topics: Acetates; Amines; Amino Acids; Animals; Anticonvulsants; Baclofen; Binding Sites; Cell Membrane; Cerebral Cortex; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Rats; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine | 1993 |
Polyamines modulate the function of transfected glutamate receptor mGluR1a.
Topics: Biogenic Polyamines; Cell Line; Cycloleucine; Female; Humans; Hydrolysis; Kidney; Phosphatidylinositols; Pregnancy; Putrescine; Receptors, Glutamate; Spermidine; Spermine; Transfection | 1993 |
Immunization of rabbits with spermine induces antibodies to self antigens.
Topics: Animals; Antibody Specificity; Autoantibodies; Autoantigens; Base Sequence; DNA; Enzyme-Linked Immunosorbent Assay; Female; Histones; Immunization; Molecular Sequence Data; Oligonucleotides; Rabbits; Spermidine; Spermine; Ubiquitins | 1993 |
Ornithine decarboxylase inactivation by putrescine: involvement of lipid peroxidation.
Topics: Animals; Dose-Response Relationship, Drug; Female; Lipid Peroxidation; Mice; Microsomes; Ornithine Decarboxylase Inhibitors; Putrescine; Skin; Spermidine; Spermine; Sulfhydryl Compounds; Sulfhydryl Reagents; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances | 1993 |
Enhanced stimulus-secretion coupling in polyamine-depleted rat insulinoma cells. An effect involving increased cytoplasmic Ca2+, inositol phosphate generation, and phorbol ester sensitivity.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Carbachol; Cytoplasm; Diazoxide; DNA, Neoplasm; Eflornithine; Glucose; Glyburide; Inositol Phosphates; Insulin; Insulin Secretion; Insulinoma; Kinetics; Pancreatic Neoplasms; Polyamines; Potassium; Putrescine; Rats; RNA, Messenger; Spermidine; Spermine; Tetradecanoylphorbol Acetate; Theophylline; Tolbutamide; Tumor Cells, Cultured | 1993 |
Polyamine metabolism in experimental brain tumors of rat.
Topics: Animals; Brain; Brain Neoplasms; Clone Cells; Functional Laterality; Glioma; Male; Organ Specificity; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Inbred F344; Spermidine; Spermine | 1993 |
An A-form of poly(amino2dA-dT).poly(amino2dA-dT) induced by polyamines.
Topics: Circular Dichroism; Nucleic Acid Conformation; Polydeoxyribonucleotides; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Spermidine; Spermine | 1993 |
Polyamine acetylation in rat liver following long-term ethanol ingestion.
Topics: Acetylation; Acetyltransferases; Alcohol Drinking; Alcoholism; Animals; Dose-Response Relationship, Drug; Liver; Male; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine | 1993 |
Chemoprevention of oral carcinogenesis by DL-alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor: dose-dependent reduction in 4-nitroquinoline 1-oxide-induced tongue neoplasms in rats.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Eflornithine; Hyperplasia; Male; Papilloma; Precancerous Conditions; Rats; Rats, Inbred ACI; Spermidine; Spermine; Tongue; Tongue Neoplasms | 1993 |
Effects of chronic 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxy- adenosine (AbeAdo) treatment on polyamine and eIF-5A metabolism in AbeAdo-sensitive and -resistant L1210 murine leukaemia cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Deoxyadenosines; Drug Resistance; Eukaryotic Translation Initiation Factor 5A; Leukemia L1210; Mice; Peptide Initiation Factors; Polyamines; RNA-Binding Proteins; S-Adenosylmethionine; Spermidine; Spermine; Tumor Cells, Cultured | 1993 |
Ornithine decarboxylase activity and urea in liver of late-pregnant rats. Effect of streptozotocin-induced diabetes.
Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Liver; Organ Size; Ornithine Decarboxylase; Pregnancy; Pregnancy in Diabetics; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Urea | 1993 |
Polyamines are necessary for cell migration by a small intestinal crypt cell line.
Topics: Animals; Cell Line; Cell Movement; Eflornithine; Intestine, Small; Intracellular Membranes; Polyamines; Putrescine; Spermidine; Spermine | 1993 |
Relationship between tissue polyamine levels and malignancy in primary brain tumors.
Topics: Adolescent; Adult; Aged; Biomarkers, Tumor; Brain; Brain Neoplasms; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Humans; Infant; Male; Middle Aged; Neoplasm Recurrence, Local; Polyamines; Putrescine; Spermidine; Spermine | 1993 |
Determination of total polyamines in tumor cells by high-performance capillary zone electrophoresis with indirect photometric detection.
Topics: Adrenal Gland Neoplasms; Animals; Diamines; Electrophoresis; PC12 Cells; Pheochromocytoma; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1993 |
Increases in brain polyamine concentrations in chemical kindling and single convulsion induced by pentylenetetrazol in rats.
Topics: Animals; Brain; Kindling, Neurologic; Male; Osmolar Concentration; Pentylenetetrazole; Putrescine; Rats; Rats, Wistar; Seizures; Spermidine; Spermine | 1993 |
Induction of hepatic polyamines by di(2-ethylhexyl)phthalate in rats.
Topics: Administration, Oral; Animals; Chromatography, Thin Layer; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Liver; Male; Rats; Rats, Wistar; Spermidine; Spermine | 1993 |
Regulation of spermidine/spermine N1-acetyltransferase by intracellular polyamine pools. Evidence for a functional role in polyamine homeostasis.
Topics: Acetyltransferases; Blotting, Northern; Eflornithine; Gene Expression Regulation, Enzymologic; Homeostasis; Humans; Melanoma; Models, Biological; Polyamines; Putrescine; RNA, Messenger; Spermidine; Spermine; Tumor Cells, Cultured | 1993 |
Release of polyamines in cultures of rat parotid and liver cells.
Topics: Animals; Cells, Cultured; Culture Media; Liver; Male; Parotid Gland; Putrescine; Rats; Spermidine; Spermine | 1993 |
Spermine promotes the survival of primary cultured brain neurons.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebellum; Hippocampus; Neurons; Piperidines; Putrescine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1993 |
Antileukemic effects of non-metabolizable derivatives of spermidine and spermine.
Topics: Adenosylmethionine Decarboxylase; Animals; Drug Synergism; Eflornithine; Female; Leukemia L1210; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Ornithine Decarboxylase; Spermidine; Spermine | 1993 |
Antioxidant properties of di- and polyamines.
Topics: Animals; Antioxidants; Brain; Erythrocytes; Female; Guinea Pigs; Heart; Humans; In Vitro Techniques; Male; Putrescine; Spermidine; Spermine; Swine | 1993 |
Transgenic mice over-producing putrescine in their tissues do not convert the diamine into higher polyamines.
Topics: Animals; Brain; Diamines; Gene Expression; Male; Mice; Mice, Transgenic; Ornithine; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Polyamines; Putrescine; Spermidine; Spermine; Testis | 1993 |
Effect of polyamines on mitochondrial F-ATPase from Crithidia fasciculata and Trypanosoma cruzi.
Topics: Adenosine Triphosphatases; Animals; Crithidia fasciculata; Hydrolysis; Kinetics; Magnesium; Mitochondria; Polyamines; Putrescine; Spermidine; Spermine; Trypanosoma cruzi | 1993 |
Segmental distribution of alpha-glucosidase, ornithine decarboxylase and polyamines in the human epididymis.
Topics: Adult; Aged; alpha-Glucosidases; Epididymis; Humans; Male; Ornithine Decarboxylase; Polyamines; Spermidine; Spermine | 1993 |
Effects of spermine and spermidine on cell division and wall morphogenesis in Saccharomyces cerevisiae.
Topics: Cell Division; Cell Wall; Kinetics; Microscopy, Electron; Morphogenesis; Saccharomyces cerevisiae; Spermidine; Spermine | 1993 |
Mucosal polyamine metabolism in the columnar lined oesophagus.
Topics: Adenocarcinoma; Barrett Esophagus; Biomarkers; Chromatography, High Pressure Liquid; Esophageal Neoplasms; Gastric Mucosa; Humans; Mucous Membrane; Polyamines; Prognosis; Putrescine; Spermidine; Spermine | 1993 |
Biogenic amines in silage. 1. The occurrence of biogenic amines in silage.
Topics: Animals; Biogenic Amines; Cadaverine; Edible Grain; Fabaceae; Histamine; Plants, Medicinal; Poaceae; Putrescine; Silage; Spermidine; Spermine | 1993 |
Ouabain releases striatal polyamines in vivo independently of N-methyl-D-aspartate receptor activation.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Male; N-Methylaspartate; Ouabain; Piperazines; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1993 |
Effects of polyamines on NMDA-induced currents in rat hippocampal neurons: a whole-cell and single-channel study.
Topics: Action Potentials; Animals; Cells, Cultured; Drug Synergism; Hippocampus; Ion Channel Gating; N-Methylaspartate; Neurons; Rats; Spermidine; Spermine | 1993 |
Osmotic effectors and DNA structure: effect of glycine on precipitation of DNA by multivalent cations.
Topics: Animals; Cations; DNA; Glycine; Models, Molecular; Nucleic Acid Conformation; Nucleic Acid Denaturation; Osmotic Pressure; Poly dA-dT; Spermidine; Spermine; Terbium | 1995 |
Spermine action on mitochondrial H(+)-ATPase activity and proliferation rate of Trypanosoma cruzi.
Topics: Animals; Cycloheximide; Eflornithine; Kinetics; Mitochondria; Proton-Translocating ATPases; Putrescine; Spermidine; Spermine; Submitochondrial Particles; Trypanosoma cruzi | 1995 |
Influence of sepsis and endotoxemia on polyamine metabolism in mucosa of small intestine in rats.
Topics: Adenosylmethionine Decarboxylase; Animals; Endotoxins; Intestinal Mucosa; Jejunum; Male; Ornithine Decarboxylase; Peritonitis; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Sepsis; Spermidine; Spermine | 1996 |
Brain polyamine levels are altered in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Biogenic Polyamines; Brain Chemistry; Calcium; Female; Humans; Male; Neurofibrillary Tangles; Putrescine; Spermidine; Spermine; Temporal Lobe | 1995 |
Stable intracellular acidification upon polyamine depletion induced by alpha-difluoromethylornithine or N1,N12-bis(ethyl)spermine in L1210 leukaemia cells.
Topics: Animals; Antineoplastic Agents; Bicarbonates; Eflornithine; Hydrogen-Ion Concentration; Leukemia L1210; Mice; Nigericin; Polyamines; Putrescine; Sodium-Hydrogen Exchangers; Spermidine; Spermine | 1995 |
Polyamines can regulate vitamin B12 dependent methionine synthase activity.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biogenic Polyamines; Cadaverine; Feedback; In Vitro Techniques; Liver; Putrescine; Rats; Spermidine; Spermine; Vitamin B 12 | 1995 |
How does the kidney deal with plasma polyamines?
Topics: Acetylation; Animals; Biological Transport, Active; Biomarkers, Tumor; Kidney; Kidney Glomerulus; Male; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1995 |
Polyamine changes in the vestibular nuclei of guinea pigs following labyrinthectomy.
Topics: Amino Acids; Animals; Brain Stem; Chromatography, High Pressure Liquid; Ear, Inner; Guinea Pigs; Image Processing, Computer-Assisted; Ornithine; Putrescine; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Vestibular Nuclei | 1994 |
Polyamine profiles in human milk, infant artificial formulas, and semi-elemental diets.
Topics: Chromatography, High Pressure Liquid; Female; Food Hypersensitivity; Food, Formulated; Humans; Infant; Infant Food; Infant, Newborn; Milk, Human; Polyamines; Putrescine; Spermidine; Spermine | 1995 |
Effect of polyamines on the separation of ovalbumin glycoforms by capillary electrophoresis.
Topics: Cadaverine; Electrophoresis, Capillary; Glycosylation; Hydrogen-Ion Concentration; Isoelectric Point; Micelles; Molecular Weight; Ovalbumin; Polyamines; Putrescine; Sodium Dodecyl Sulfate; Spermidine; Spermine | 1996 |
Inhibition of polyamine synthesis alters hair follicle function and fiber composition.
Topics: Adenosylmethionine Decarboxylase; Animals; Culture Media; Eflornithine; Enzyme Inhibitors; Gene Expression; Hair; Hair Follicle; Keratins; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Sheep; Spermidine; Spermine | 1996 |
Complexation of spermine and spermidine by myo-inositol 1,4,5-tris(phosphate) and related compounds: biological significance.
Topics: Adenosine Triphosphate; Binding Sites; Drug Stability; Hydrogen-Ion Concentration; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Protons; Signal Transduction; Spermidine; Spermine | 1996 |
DNA aggregation induced by polyamines and cobalthexamine.
Topics: Animals; Base Composition; Cattle; Cobalt; DNA; Kinetics; Osmolar Concentration; Sodium Chloride; Solubility; Solutions; Spermidine; Spermine; Thymus Gland | 1996 |
Regulation by spermine of native inward rectifier K+ channels in RBL-1 cells.
Topics: Animals; Deoxyadenosines; Eflornithine; Leukemia, Basophilic, Acute; Membrane Potentials; Ornithine Decarboxylase Inhibitors; Potassium Channels; Potassium Channels, Inwardly Rectifying; Putrescine; Rats; Spermidine; Spermine; Tumor Cells, Cultured | 1996 |
Polyamine-induced compaction and aggregation of DNA--a major factor in radioprotection of chromatin under physiological conditions.
Topics: Animals; Cells, Cultured; CHO Cells; Cricetinae; DNA; DNA Damage; DNA, Viral; Gamma Rays; HeLa Cells; Humans; Leukocytes; Putrescine; Radiation Protection; Simian virus 40; Spermidine; Spermine | 1996 |
Impairment of DNA replication within one cell cycle after seeding of cells in the presence of a polyamine-biosynthesis inhibitor.
Topics: Animals; Bromodeoxyuridine; Cell Cycle; CHO Cells; Cricetinae; DNA; DNA Replication; Eflornithine; Enzyme Inhibitors; Kinetics; Ornithine Decarboxylase Inhibitors; Polyamines; Protein Biosynthesis; Putrescine; RNA; Spermidine; Spermine | 1996 |
First report of the inhibition of arbuscular mycorrhizal infection of Pisum sativum by specific and irreversible inhibition of polyamine biosynthesis or by gibberellic acid treatment.
Topics: Cadaverine; Eflornithine; Enzyme Inhibitors; Fungi; Gibberellins; Mutation; Ornithine Decarboxylase Inhibitors; Pisum sativum; Plant Diseases; Plant Growth Regulators; Plant Roots; Polyamines; Putrescine; Spermidine; Spermine | 1996 |
The mechanism of inward rectification of potassium channels: "long-pore plugging" by cytoplasmic polyamines.
Topics: Animals; Cloning, Molecular; Cytoplasm; Female; Ion Channel Gating; Kinetics; Oocytes; Patch-Clamp Techniques; Polyamines; Potassium Channel Blockers; Potassium Channels; Putrescine; Spermidine; Spermine; Time Factors; Xenopus | 1995 |
Inhibition of cell growth by accumulated spermine is associated with a transient alteration of cell cycle progression.
Topics: Cell Cycle; Cell Division; Flow Cytometry; Growth Inhibitors; HL-60 Cells; Humans; Ornithine Decarboxylase; Spermidine; Spermine | 1996 |
Effect of vitamin E deficiency on inhibition of liver regeneration by long-term administration of alcohol.
Topics: Animals; DNA Replication; Ethanol; Hepatectomy; Lipid Peroxidation; Liver; Liver Diseases, Alcoholic; Liver Regeneration; Male; Ornithine Decarboxylase; Rats; Rats, Wistar; Spermidine; Spermine; Vitamin E Deficiency | 1996 |
Purification and properties of transglutaminase from soybean (Glycine max) leaves.
Topics: Calcium; Caseins; Chromatography, Affinity; Chromatography, Ion Exchange; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Glycine max; Kinetics; Molecular Weight; Putrescine; Spermidine; Spermine; Substrate Specificity; Transglutaminases | 1996 |
Effect of three novel polyamine oxa-analogues (MTR-OSPD, DIP-SPN and APPO-TFA) on the growth and proliferation of Swiss 3T3 cells.
Topics: 3T3 Cells; Animals; Cell Division; Chromans; DNA; Imines; Mice; Molecular Structure; Phthalimides; RNA; Spermidine; Spermine; Sulfonamides | 1996 |
Automated determination of polyamines by high-performance liquid chromatography with simple sample preparation.
Topics: Amino Acids; Animals; Autoanalysis; Cadaverine; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; o-Phthalaldehyde; Polyamines; Putrescine; Reproducibility of Results; Spermidine; Spermine; Swine | 1996 |
Polyamines decrease Escherichia coli outer membrane permeability.
Topics: Biogenic Polyamines; Cadaverine; Cell Membrane Permeability; Cephaloridine; Chemotaxis; Escherichia coli; Putrescine; Spermidine; Spermine | 1996 |
Regulation of a high-affinity diamine transport system in Trypanosoma cruzi epimastigotes.
Topics: Animals; Biological Transport; Cadaverine; Carrier Proteins; Cell Division; Cycloheximide; Dactinomycin; Down-Regulation; Ionophores; Kinetics; Putrescine; Spermidine; Spermine; Sulfhydryl Reagents; Trypanosoma cruzi; Up-Regulation | 1996 |
Inhibition of hepatocellular carcinoma development and erythrocyte polyamine levels in ODS rats fed on 3'-methyl-4-dimethylaminoazobenzene by hemicalcium ascorbate, 2-O-octadecylascorbic acid, and ascorbyl palmitate.
Topics: Animals; Antimutagenic Agents; Ascorbic Acid; Body Weight; Carcinogens; Erythrocytes; Free Radical Scavengers; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Organ Size; Putrescine; Rats; Spermidine; Spermine | 1996 |
Differential post-transcriptional control of ornithine decarboxylase and spermidine-spermine N1-acetyltransferase by polyamines.
Topics: Acetyltransferases; Blotting, Northern; Cell Line; Cycloheximide; Gene Expression Regulation, Enzymologic; Humans; Kinetics; Melanoma; Ornithine Decarboxylase; Protein Biosynthesis; RNA, Messenger; Spermidine; Spermine; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Effects of polyamine imbalance on the induction of stress genes in hepatocarcinoma cells exposed to heat shock.
Topics: Animals; Cell Division; Eflornithine; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, Immediate-Early; Genes, jun; Heme Oxygenase (Decyclizing); Histones; HSP70 Heat-Shock Proteins; Humans; Kinetics; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; RNA, Messenger; Spermidine; Spermine; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Polyamines in frontal cortex of patients with Down syndrome and Alzheimer disease.
Topics: Aged; Alzheimer Disease; Case-Control Studies; Choline O-Acetyltransferase; Down Syndrome; Female; Frontal Lobe; Humans; Male; Middle Aged; Spermidine; Spermine | 1996 |
Enhanced tissue polyamine content in the spontaneously hypertensive rat.
Topics: Animals; Blood Vessels; Cardiovascular System; Eflornithine; Enzyme Inhibitors; Heart Ventricles; Liver; Male; Polyamines; Putrescine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spermidine; Spermine | 1996 |
High performance liquid chromatography separation and simultaneous fluorometric detection of trace amount of polyamines in cell culture media.
Topics: Animals; Cell Hypoxia; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium, Vascular; Fluorometry; Polyamines; Pulmonary Artery; Putrescine; Spermidine; Spermine; Swine | 1995 |
Changes in composition and polyamine content in the gastrointestinal tract due to pathogenic infection.
Topics: Animals; Cecum; DNA; Ileum; Intestinal Mucosa; Intestines; Male; Polyamines; Putrescine; Rats; Rats, Inbred Strains; RNA; Salmonella enteritidis; Salmonella Infections, Animal; Salmonella typhimurium; Spermidine; Spermine | 1996 |
Putrescine transport in differentiated Caco-2 cells.
Topics: Biological Transport, Active; Caco-2 Cells; Cystamine; Enzyme Inhibitors; Guanidines; Humans; In Vitro Techniques; Mitoguazone; Putrescine; Spermidine; Spermine | 1996 |
The potential of a novel polyamine transport inhibitor in cancer chemotherapy.
Topics: Antineoplastic Agents; Dose-Response Relationship, Drug; Humans; Leukemia; Polyamines; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1996 |
Effects of female sex hormones on polyamine-oxidizing enzyme activities and polyamine concentrations in immature rat uterus and liver.
Topics: Amine Oxidase (Copper-Containing); Animals; Estradiol; Female; Liver; Organ Size; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Progesterone; Putrescine; Rats; Spermidine; Spermine; Uterus | 1996 |
Reactive oxygen and nitrogen intermediates and products from polyamine degradation are Babesiacidal in vitro.
Topics: Acrolein; Animals; Antiprotozoal Agents; Babesia bovis; Catalase; Hydrogen Peroxide; Hydroxides; Nitrites; Nitroprusside; Oxidants; Penicillamine; Polyamines; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Spermidine; Spermine; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1996 |
Partial purification and characterization of ornithine decarboxylase from Entamoeba histolytica.
Topics: Animals; Cell Division; Entamoeba histolytica; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Protozoan Proteins; Putrescine; Spermidine; Spermine | 1996 |
Uptake mechanism of trientine by rat intestinal brush-border membrane vesicles.
Topics: Animals; Chromatography, High Pressure Liquid; Diffusion; Intestine, Small; Male; Microvilli; Potassium; Rats; Rats, Wistar; Spermidine; Spermine; Temperature; Time Factors; Trientine; Valinomycin | 1996 |
The involvement of polyamines in the proliferation of cultured retinal pigment epithelial cells.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Cattle; Cell Division; Cells, Cultured; DNA; DNA Replication; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ornithine Decarboxylase; Pigment Epithelium of Eye; Putrescine; Spermidine; Spermine | 1996 |
Effects of a single dose of orally-administered spermine on the intestinal development of unweaned rats.
Topics: Administration, Oral; alpha-Glucosidases; Animals; Animals, Suckling; beta-Galactosidase; Drug Administration Schedule; Enzyme Induction; Intestine, Small; Lactase; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Sucrase | 1996 |
Molecular requirements for polyamines binding to the antispermine monoclonal antibody Spm8-2.
Topics: Acetylation; Animals; Antibodies, Monoclonal; Enzyme-Linked Immunosorbent Assay; Immunoglobulin Fab Fragments; Mice; Osmolar Concentration; Polyamines; Putrescine; Spermidine; Spermine | 1996 |
Production and characterization of a monoclonal antibody specific for the polyamine spermidine and its application in ELISA.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Mice; Mice, Inbred BALB C; Spermidine; Spermine | 1996 |
The contribution of endogenous polyamines to the permeability transition of rat liver mitochondria.
Topics: Animals; Calcium; Chromatography, High Pressure Liquid; Cyclosporine; Kinetics; Magnesium; Mitochondria, Liver; Mitochondrial Swelling; Permeability; Phosphates; Rats; Spermidine; Spermine | 1996 |
High levels of spermine in IVF medium as a negative predictor of subsequent success of embryo transfer.
Topics: Culture Media, Conditioned; Embryo Transfer; Enzyme-Linked Immunosorbent Assay; Female; Fertilization in Vitro; Humans; Polyamines; Pregnancy; Pregnancy Outcome; Spermidine; Spermine | 1996 |
Rectification of rabbit cardiac ryanodine receptor current by endogenous polyamines.
Topics: Animals; Calcium Channels; Electric Conductivity; Heart; Heart Ventricles; Ion Channel Gating; Lipid Bilayers; Membrane Potentials; Muscle Proteins; Myocardium; Putrescine; Rabbits; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Spermidine; Spermine | 1996 |
Intracellular distribution of polyamines in human lymphoblastoid cell line during phorbol ester-induced differentiation.
Topics: B-Lymphocytes; Cell Cycle; Cell Differentiation; Cell Division; Humans; Leucine; Leukemia, Lymphoid; Putrescine; Spermidine; Spermine; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured | 1996 |
Polyamine content of Pneumocystis carinii and response to the ornithine decarboxylase inhibitor DL-alpha-difluoromethylornithine.
Topics: Animals; Chromatography, High Pressure Liquid; Eflornithine; Enzyme Inhibitors; Ornithine Decarboxylase Inhibitors; Pneumocystis; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1996 |
Polyamine metabolism in gliomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Female; Glioma; Humans; Infant; Male; Middle Aged; Necrosis; Oligodendroglioma; Ornithine Decarboxylase; Putrescine; Recurrence; Spermidine; Spermine | 1996 |
Substrate protection against inactivation of the mammalian polyamine-transport system by 1-ethyl-3-(3-dimethylaminopropyl)carbodi-imide.
Topics: Aminoisobutyric Acids; Animals; Biological Transport, Active; Cell Line; Cricetinae; Cricetulus; Dicyclohexylcarbodiimide; Dose-Response Relationship, Drug; Ethyldimethylaminopropyl Carbodiimide; Female; Hydrogen-Ion Concentration; Kinetics; Ovary; Putrescine; Spermidine; Spermine | 1996 |
Mechanism of oligonucleotide release from cationic liposomes.
Topics: Base Sequence; Cell Membrane; DNA; Endocytosis; Energy Transfer; Hydrogen-Ion Concentration; Liposomes; Microscopy, Confocal; Models, Biological; Oligodeoxyribonucleotides; Osmolar Concentration; RNA, Transfer; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spermidine; Spermine; Structure-Activity Relationship; Thionucleotides | 1996 |
Aging and polyamine acetylation in rat kidney.
Topics: Acetylation; Acetyltransferases; Aging; Animals; Histones; Kidney; Male; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Substrate Specificity | 1996 |
Differing effects of polyamines on nitric oxide synthase.
Topics: Animals; Cerebellum; Cerebral Cortex; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Nitric Oxide Synthase; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1996 |
Cytotoxicity of polyamines to Amoeba proteus: role of polyamine oxidase.
Topics: Amebicides; Amoeba; Animals; Cells, Cultured; Emetine; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Spermidine; Spermine; Toxicity Tests | 1996 |
Estimation of 24-hour polyamine intake from mature human milk.
Topics: Female; Humans; Milk, Human; Polyamines; Putrescine; Spermidine; Spermine; Time Factors | 1996 |
Influence of iron deficiency and lead treatment on behavior and cerebellar and hippocampal polyamine levels in neonatal rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cerebellum; Electroshock; Escape Reaction; Female; Growth; Hippocampus; Iron Deficiencies; Lead; Learning; Male; Maze Learning; Memory; Motivation; Motor Activity; Neuroglia; Neurons; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1996 |
2,2'-Dithiobis(N-ethyl-spermine-5-carboxamide) is a high affinity, membrane-impermeant antagonist of the mammalian polyamine transport system.
Topics: Animals; Breast Neoplasms; Cell Division; Cell Membrane; CHO Cells; Cricetinae; Cycloheximide; Cysteamine; Disulfides; Female; Humans; Indicators and Reagents; Kinetics; Molecular Structure; Polyamines; Putrescine; Spermidine; Spermine; Structure-Activity Relationship; Sulfhydryl Compounds; Tumor Cells, Cultured | 1996 |
Mucosal polyamine measurements and colorectal cancer risk.
Topics: Aged; Colorectal Neoplasms; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Polyamines; Risk Factors; Spermidine; Spermine | 1996 |
Acrosome membrane associated protein kinase activity in hamster spermatozoa.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acrosome; Animals; Cricetinae; Cyclic AMP; Enzyme Inhibitors; Epididymis; Genistein; Heparin; Isoflavones; Male; Membrane Proteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Spermidine; Spermine | 1996 |
Regulation of polyamine synthesis and transport by fibroblast growth factor in aortic smooth muscle cells.
Topics: Animals; Aorta; Blotting, Northern; Cycloheximide; Dactinomycin; Fibroblast Growth Factor 2; Muscle, Smooth, Vascular; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spermidine; Spermine | 1996 |
Control of ornithine decarboxylase activity by polyamines and absence of antizyme in Tetrahymena.
Topics: Animals; Biogenic Polyamines; Enzyme Inhibitors; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Proteins; Putrescine; Spermidine; Spermine; Tetrahymena | 1996 |
Immunocytochemical localization of polyamines in the gastrointestinal tracts of rats and mice.
Topics: Animals; Antibodies, Monoclonal; Digestive System; Immunohistochemistry; Intestine, Large; Intestine, Small; Male; Mice; Pylorus; Rats; Rats, Wistar; Spermidine; Spermine; Stomach; Tissue Distribution | 1996 |
Polyamine levels in various tissues of rats treated with 3-hydroxy-4-methoxycinnamic acid and 3,4-dimethoxycinnamic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biogenic Polyamines; Body Weight; Buffers; Cinnamates; Diet; Indicators and Reagents; Male; Organ Size; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Tissue Distribution | 1996 |
Polyamines enhance calcium pyrophosphate dihydrate crystal dissolution.
Topics: Alkaline Phosphatase; Calcium Pyrophosphate; Crystallization; Ions; Magnesium; Microscopy, Electron, Scanning; Osmolar Concentration; Polyamines; Pyrophosphatases; Spermidine; Spermine | 1995 |
[New aminooxy analogs of biogenic polyamines].
Topics: Animals; Cell Division; Cell Line; Cricetinae; Leukemia L1210; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1996 |
Ornithine decarboxylase and polyamines in familial adenomatous polyposis.
Topics: Adenomatous Polyposis Coli; Adolescent; Adult; Biomarkers, Tumor; Child; Colorectal Neoplasms; Female; Genotype; Humans; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1997 |
Erythrocyte spermine levels: a prognostic parameter in childhood common acute lymphoblastic leukemia.
Topics: Adolescent; Child; Child, Preschool; Disease-Free Survival; Erythrocytes; Female; Humans; Infant; Leukocyte Count; Male; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Probability; Prognosis; Prospective Studies; Sensitivity and Specificity; Spermidine; Spermine | 1997 |
The effects of spermine and spermidine on the structure of photosystem II proteins in relation to inhibition of electron transport.
Topics: Cations; Electron Transport; Hydrogen Bonding; Oxygen; Photosynthesis; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Spermidine; Spermine | 1997 |
Dissimilar activation patterns of the carcinogen dimethylhydrazine (DMH) on intracellular polyamine metabolism in various organs.
Topics: 1,2-Dimethylhydrazine; Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Eflornithine; Enzyme Activation; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Tissue Distribution | 1996 |
Relationship between adipose polyamine concentrations and triacylglycerol synthetic enzymes in lean and obese Zucker rats.
Topics: Acyltransferases; Adipose Tissue; Animals; Chromatography, High Pressure Liquid; Diacylglycerol O-Acyltransferase; Glycerol-3-Phosphate O-Acyltransferase; Glycolipids; Male; Obesity; Phosphatidate Phosphatase; Polyamines; Rats; Rats, Zucker; Spermidine; Spermine; Triglycerides | 1996 |
Growth arrest- and polyamine-dependent expression of spermidine/spermine N1-acetyltransferase in human tumor cells.
Topics: Acetyltransferases; Blotting, Northern; Cell Division; Colonic Neoplasms; Dactinomycin; Eflornithine; Enzyme Induction; Enzyme Repression; Heat-Shock Response; Humans; Polyamines; Putrescine; RNA; Spermidine; Spermine; Tumor Cells, Cultured | 1996 |
Modulation of maize roots H(+)-ATPase by sulfated polysaccharides.
Topics: Cell Membrane; Dextran Sulfate; Hydrogen-Ion Concentration; Kinetics; Lysophosphatidylcholines; Plant Roots; Polysaccharides; Potassium; Proton-Translocating ATPases; Sodium; Spermidine; Spermine; Sulfates; Temperature; Zea mays | 1996 |
Chemical features of the protein kinase CK2 polyamine binding site.
Topics: Animals; Casein Kinase II; DNA-Binding Proteins; Drosophila; Hydrogen-Ion Concentration; Polyamines; Protein Serine-Threonine Kinases; Putrescine; Sodium Chloride; Spermidine; Spermine | 1997 |
Polyamine contents of human breast cancer cells treated with the cytotoxic agents chlorpheniramine and dehydrodidemnin B.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Chlorpheniramine; Depsipeptides; Female; Humans; Ornithine Decarboxylase; Peptides, Cyclic; Spermidine; Spermine; Tumor Cells, Cultured | 1997 |
Redistribution of DNA topoisomerase II beta after in vitro stabilization of human erythroleukemic nuclei by heat or Cu++ revealed by confocal microscopy.
Topics: Antibodies, Monoclonal; Cell Nucleus; Copper; DNA Topoisomerases, Type II; Fluorescent Antibody Technique, Indirect; Heating; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Leukemia, Erythroblastic, Acute; Magnesium; Microscopy, Confocal; Potassium Chloride; Spermidine; Spermine; Tumor Cells, Cultured | 1997 |
Tolerance to putrescine toxicity in Chinese hamster ovary cells is associated with altered uptake and export.
Topics: Amine Oxidase (Copper-Containing); Animals; Biological Transport; Carrier Proteins; CHO Cells; Cricetinae; Cricetulus; Drug Resistance; Drug Tolerance; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine | 1997 |
Polyamines prevent apoptotic cell death in cultured cerebellar granule neurons.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Cerebellum; Cysteine Endopeptidases; Enzyme Precursors; Neurons; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1997 |
beta-Endorphin enhances polyamine transport in human lymphocytes.
Topics: Adrenocorticotropic Hormone; alpha-Endorphin; beta-Endorphin; Biological Transport; Cells, Cultured; Enkephalin, Methionine; Humans; Lymphocytes; Neuropeptides; Neurotransmitter Agents; Polyamines; Spermidine; Spermine | 1997 |
Decrease in myocardial polyamine concentration in rats with myocardial infarction.
Topics: Animals; Male; Myocardial Infarction; Myocardium; Norepinephrine; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Ventricular Function, Left | 1997 |
4-Amidinoindan-1-one 2'-amidinohydrazone (CGP 48664A) exerts in vitro growth inhibitory effects that are not only related to S-adenosylmethionine decarboxylase (SAMdc) inhibition.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Antineoplastic Agents; Cell Division; Deoxyadenosines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indans; Leukemia L1210; Mitoguazone; Spermidine; Spermine; Tumor Cells, Cultured | 1997 |
Involvement of polyamines in the protection of taurine against the cytotoxicity of hydrazine or carbon tetrachloride in isolated rat hepatocytes.
Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Hydrazines; L-Lactate Dehydrogenase; Liver; Male; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Taurine | 1997 |
Fasting gastric fluid and fecal polyamine concentrations in premature infants.
Topics: Aging; Cadaverine; Chromatography, High Pressure Liquid; Fasting; Feces; Gastric Juice; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Polyamines; Putrescine; Reference Values; Spermidine; Spermine | 1997 |
A comparison of structure-activity relationships between spermidine and spermine analogue antineoplastics.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Cell Division; Leukemia L1210; Magnetic Resonance Spectroscopy; Ornithine Decarboxylase; Polyamines; Spermidine; Spermine; Tumor Cells, Cultured | 1997 |
Enteral supplementation with ornithine alpha ketoglutarate improves the early adaptive response to resection.
Topics: Adaptation, Biological; Animals; Blotting, Northern; Caseins; Enteral Nutrition; Food, Fortified; Hyperplasia; Ileum; Jejunostomy; Male; Ornithine; Postoperative Period; Protein Hydrolysates; Putrescine; Rats; Rats, Wistar; RNA, Messenger; Spermidine; Spermine; Sucrase | 1997 |
Effects of the polyamine analogues BE-4-4-4-4, BE-3-7-3, and BE-3-3-3 on the proliferation of three prostate cancer cell lines.
Topics: Animals; Antineoplastic Agents; Cell Division; Growth Inhibitors; Male; Mice; Mice, Nude; Polyamines; Propylamines; Prostatic Neoplasms; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1997 |
Ozone stress modulates amine oxidase and lipoxygenase expression in lentil (Lens culinaris) seedlings.
Topics: Amine Oxidase (Copper-Containing); Fabaceae; Gene Expression Regulation, Plant; Lipid Peroxidation; Lipid Peroxides; Lipoxygenase; Lipoxygenase Inhibitors; Membrane Lipids; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Ozone; Plants, Medicinal; Polyamines; Putrescine; RNA, Messenger; Seeds; Spermidine; Spermine | 1997 |
Complex inhibition of OmpF and OmpC bacterial porins by polyamines.
Topics: Binding Sites; Cadaverine; Electrophysiology; Escherichia coli; Ion Channel Gating; Kinetics; Models, Chemical; Polyamines; Porins; Putrescine; Spermidine; Spermine | 1997 |
Activation of polyamine catabolism profoundly alters tissue polyamine pools and affects hair growth and female fertility in transgenic mice overexpressing spermidine/spermine N1-acetyltransferase.
Topics: Acetyltransferases; Animals; Blotting, Northern; Cell Differentiation; Epidermal Cells; Female; Gene Dosage; Gene Expression; Hair; Infertility, Female; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Transgenic; Phenotype; Polyamines; Putrescine; RNA, Messenger; Spermidine; Spermine; Tissue Distribution | 1997 |
Overexpression of arginine decarboxylase in transgenic plants.
Topics: Adenosylmethionine Decarboxylase; Agmatine; Amine Oxidase (Copper-Containing); Avena; Carboxy-Lyases; Carboxyl and Carbamoyl Transferases; Cloning, Molecular; Gene Expression Regulation, Plant; Hydrolases; Nicotiana; Nicotine; Ornithine Decarboxylase; Plants, Genetically Modified; Plants, Toxic; Polyamines; Putrescine; Spermidine; Spermine; Transferases; Transformation, Genetic; Ureohydrolases | 1997 |
Partial restoration of inactivated ribosomes: role of the aldehyde group generated by RNA N-glycosidase in the sarcin/ricin domain of 28S rRNA in ribosome.
Topics: Aldehydes; Algal Proteins; Amino Acids; Animals; Binding Sites; Borohydrides; Endoribonucleases; Fungal Proteins; N-Glycosyl Hydrolases; Polyamines; Protein Biosynthesis; Proteins; Rats; Ribosome Inactivating Proteins; Ribosome Inactivating Proteins, Type 2; Ribosomes; Ricin; RNA, Ribosomal, 28S; Spermidine; Spermine | 1997 |
Polyamines and their potential to be antimutagens.
Topics: Antimutagenic Agents; DNA; Dose-Response Relationship, Drug; Mutagenicity Tests; Mutation; Polyamines; Putrescine; Spermidine; Spermine | 1997 |
Effects of sevoflurane on inward rectifier K+ current in guinea pig ventricular cardiomyocytes.
Topics: Anesthetics, Inhalation; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Ethers; Guinea Pigs; Heart; Heart Ventricles; Kinetics; Magnesium; Membrane Potentials; Methyl Ethers; Models, Biological; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Regression Analysis; Sevoflurane; Spermidine; Spermine | 1997 |
Inhibition of polyamine synthesis influences contractility of intestinal smooth muscle in culture.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Calcium; Cells, Cultured; Enzyme Inhibitors; Female; Guinea Pigs; Ileum; Indans; Kinetics; Muscle Contraction; Muscle, Smooth; Polyamines; Potassium; Putrescine; Spermidine; Spermine | 1997 |
Polyamines are important for attachment of IEC-6 cells to extracellular matrix.
Topics: Animals; Cadaverine; Cell Adhesion; Cell Line; Cell Movement; Collagen; Drug Combinations; Eflornithine; Enzyme Inhibitors; Extracellular Matrix; Integrins; Intestinal Mucosa; Intestine, Small; Laminin; Ornithine Decarboxylase; Plastics; Polyamines; Proteoglycans; Putrescine; Rats; Spermidine; Spermine | 1997 |
Raised erythrocyte polyamine levels in non-insulin-dependent diabetes mellitus with great vessel disease and albuminuria.
Topics: Albuminuria; Arterial Occlusive Diseases; Blood Pressure; Cholesterol; Cholesterol, HDL; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Erythrocytes; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Polyamines; Spermidine; Spermine; Triglycerides | 1997 |
Inhibition of methionine adenosyltransferase by the polyamines.
Topics: Animals; Enzyme Inhibitors; Humans; Isoenzymes; Lens, Crystalline; Leukemia; Lymphocyte Activation; Methionine Adenosyltransferase; Mitogens; Phosphates; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Retina; S-Adenosylmethionine; Spermidine; Spermine; T-Lymphocytes | 1997 |
Effect of glycine on DNA structural transitions induced by multivalent cationic compounds.
Topics: Chemical Precipitation; Circular Dichroism; DNA; Glycine; Light; Scattering, Radiation; Spermidine; Spermine; Terbium | 1997 |
Effect of polyamine-induced compaction and aggregation of DNA on the formation of radiation-induced strand breaks: quantitative models for cellular radiation damage.
Topics: Cystamine; Disulfides; DNA Damage; DNA, Single-Stranded; DNA, Viral; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Gamma Rays; Glutathione; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Mercaptoethylamines; Models, Genetic; Polyamines; Putrescine; Radiation-Protective Agents; Simian virus 40; Spermidine; Spermine; Sulfhydryl Compounds | 1997 |
Polyamine metabolism in the thermotolerant mesophilic fungus Aspergillus fumigatus.
Topics: Adenosylmethionine Decarboxylase; Aspergillus fumigatus; Cadaverine; Carboxy-Lyases; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Temperature | 1997 |
Inhibition of platelet aggregation by L-arginine and polyamines in alloxan treated rats.
Topics: Animals; Arginase; Arginine; Diabetes Mellitus, Experimental; Humans; Insulin; Male; Plasma; Platelet Aggregation; Platelet Aggregation Inhibitors; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine | 1997 |
The Ca2+-sensing receptor: a target for polyamines.
Topics: Animals; Calcium; Cattle; Cell Line; Cells, Cultured; Humans; Kidney; Membrane Potentials; Parathyroid Glands; Parathyroid Hormone; Patch-Clamp Techniques; Receptors, Calcium-Sensing; Receptors, Cell Surface; Recombinant Proteins; Spermidine; Spermine; Transfection | 1997 |
Rapid induction of apoptosis by deregulated uptake of polyamine analogues.
Topics: Alkylation; Animals; Apoptosis; Cell Death; CHO Cells; Cricetinae; Cycloheximide; Cysteine Proteinase Inhibitors; Eflornithine; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Putrescine; Spermidine; Spermine | 1997 |
New spermine and spermidine derivatives as potent inhibitors of Trypanosoma cruzi trypanothione reductase.
Topics: Animals; Enzyme Inhibitors; NADH, NADPH Oxidoreductases; Protozoan Proteins; Spermidine; Spermine; Structure-Activity Relationship; Trypanosoma cruzi | 1997 |
Oral administration of deuterium-labelled polyamines to sucking rat pups: luminal uptake, metabolic fate and effects on gastrointestinal maturation.
Topics: Amine Oxidase (Copper-Containing); Animals; Animals, Suckling; Cecum; Colon; Deuterium; Disaccharidases; Erythrocytes; Heart; Ileum; Kidney; Liver; Organ Size; Polyamines; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine | 1997 |
Diagnostic and prognostic usefulness of N1,N8-diacetylspermidine and N1,N12-diacetylspermine in urine as novel markers of malignancy.
Topics: Adult; Biomarkers, Tumor; Female; Humans; Male; Middle Aged; Neoplasms; Prognosis; Spermidine; Spermine; Time Factors | 1997 |
Selective labelling of cell-surface polyamine-binding proteins on leukaemic and solid-tumour cell types using a new polyamine photoprobe.
Topics: Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Cell Membrane; Cross-Linking Reagents; Humans; Intracellular Signaling Peptides and Proteins; Iodine Radioisotopes; Kinetics; Leukemia L1210; Lung Neoplasms; Membrane Proteins; Mice; Mitoguazone; Photoaffinity Labels; Polyamines; Spermidine; Spermine; Tumor Cells, Cultured | 1997 |
Transfection of myoblasts in primary culture with isomeric cationic cholesterol derivatives.
Topics: Animals; Cations; Cells, Cultured; Cholesterol; Chromatography, High Pressure Liquid; DNA; Dogs; Genes, Reporter; Humans; Isomerism; Liposomes; Luciferases; Magnetic Resonance Spectroscopy; Molecular Structure; Muscle Fibers, Skeletal; Plasmids; Spermidine; Spermine; Transfection; Tumor Cells, Cultured | 1997 |
Neurotoxicity of polyamines and pharmacological neuroprotection in cultures of rat cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Aspartic Acid; Butylated Hydroxytoluene; Cells, Cultured; Cerebellar Cortex; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Free Radical Scavengers; Glutamic Acid; L-Lactate Dehydrogenase; Male; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitroarginine; Piperidines; Putrescine; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Vitamin E | 1997 |
Polyamine metabolism in various tissues during pathogenesis of chloroquine-susceptible and resistant malaria.
Topics: Adenosylmethionine Decarboxylase; Animals; Antimalarials; Brain; Chloroquine; Drug Resistance; Erythrocytes; Heart; Kidney; Liver; Lung; Malaria; Muridae; Myocardium; Organ Size; Ornithine Decarboxylase; Plasmodium berghei; Polyamines; Spermidine; Spermine; Spleen | 1997 |
Polyamines in goat's colostrum and milk.
Topics: Animals; Cattle; Circadian Rhythm; Colostrum; Female; Goats; Humans; Lactation; Milk; Polyamines; Putrescine; Rats; Species Specificity; Spermidine; Spermine; Swine | 1997 |
[Changes in tissue and blood polyamine levels following chemotherapy in rats with urinary bladder carcinoma induced by N-butyl-N-(4-hydroxybutyl) nitosamine in rats].
Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Carcinogens; Diamines; Male; Polyamines; Rats; Rats, Inbred F344; Spermidine; Spermine; Urinary Bladder Neoplasms | 1997 |
Human prostatic carcinoma cell lines display altered regulation of polyamine transport in response to polyamine analogs and inhibitors.
Topics: Adenosylmethionine Decarboxylase; Amidines; Biological Transport; Growth Inhibitors; Humans; Indans; Male; Molecular Structure; Polyamines; Prostatic Neoplasms; Spermidine; Spermine; Tumor Cells, Cultured | 1998 |
Filarial DNA and its interaction with polyamines and antifilarial drugs.
Topics: Animals; Antinematodal Agents; DNA, Helminth; Setaria Nematode; Spermidine; Spermine; Suramin | 1997 |
Precipitation of DNA by polyamines: a polyelectrolyte behavior.
Topics: Animals; Cattle; Chemical Precipitation; Chromatin; DNA; Kinetics; Models, Chemical; Osmolar Concentration; Polydeoxyribonucleotides; Sodium Chloride; Spermidine; Spermine | 1998 |
Metabolism of polyamines in transgenic cells of carrot expressing a mouse ornithine decarboxylase cDNA.
Topics: Animals; Arginine; Biological Transport; Cell Line; Daucus carota; DNA, Complementary; Mice; Ornithine; Ornithine Decarboxylase; Plants, Genetically Modified; Polyamines; Putrescine; Recombinant Proteins; Spermidine; Spermine; Transfection | 1998 |
Polyamine derivatives as inhibitors of trypanothione reductase and assessment of their trypanocidal activities.
Topics: Animals; Enzyme Inhibitors; Female; Mice; Models, Chemical; NADH, NADPH Oxidoreductases; Spermidine; Spermine; Trypanocidal Agents; Trypanosoma cruzi | 1997 |
Intracellular levels of polyamines in Krebs II lymphosarcoma cells in mice fed phytohaemagglutinin-containing diets are coupled with altered tumour growth.
Topics: Animals; Cell Division; Female; Heart; Hyperplasia; Intestine, Small; Kidney; Lymphoma, Non-Hodgkin; Mice; Mice, Inbred Strains; Muscle Development; Muscle, Skeletal; Neoplasm Transplantation; Organ Size; Phytohemagglutinins; Polyamines; Putrescine; Spermidine; Spermine; Stomach; Time Factors | 1997 |
Hydrogen peroxide assay for amine oxidase activity.
Topics: Amine Oxidase (Copper-Containing); Fluorometry; Homovanillic Acid; Horseradish Peroxidase; Hydrogen Peroxide; Oxidoreductases Acting on CH-NH Group Donors; Putrescine; Sensitivity and Specificity; Spermidine; Spermine | 1998 |
Radiochemical estimation of polyamine oxidase.
Topics: Animals; Benzaldehydes; Carbon Radioisotopes; Chromatography, Ion Exchange; Liver; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Radiochemistry; Rats; Scintillation Counting; Spermidine; Spermine | 1998 |
Measurement of aldehyde formation as an assay for polyamine oxidase activity.
Topics: Aldehydes; Benzothiazoles; Colorimetry; Hydrazones; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Spermine; Thiazoles | 1998 |
Determination of polyamines as their benzoylated derivatives by HPLC.
Topics: Benzoates; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium; Macrophages; Polyamines; Putrescine; Spermidine; Spermine | 1998 |
A dansyl chloride-HPLC method for the determination of polyamines.
Topics: Chromatography, High Pressure Liquid; Dansyl Compounds; Polyamines; Putrescine; Spermidine; Spermine | 1998 |
The determination of polyamines and amino acids by a fluorescamine-HPLC method.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Fluorescamine; Indicators and Reagents; Polyamines; Putrescine; Spermidine; Spermine | 1998 |
Thin-layer chromatographic method for assaying polyamines.
Topics: Amides; Animals; Chromatography, Thin Layer; Dansyl Compounds; Indicators and Reagents; Leishmania donovani; Polyamines; Putrescine; Spermidine; Spermine | 1998 |
Measurement of polyamine transport. Adherent cells.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Cell Adhesion; Endothelium, Vascular; Humans; Macrophages; Mice; Muscle, Smooth, Vascular; Polyamines; Putrescine; Spermidine; Spermine | 1998 |
Measurement of polyamine transport. Cells in suspension.
Topics: Animals; Biological Transport; Centrifugation; Polyamines; Putrescine; Silicone Oils; Spermidine; Spermine; Trichloroacetic Acid; Tritium; Trypanosomatina | 1998 |
Measurement of polyamine efflux from cells in culture.
Topics: Biological Transport; Chromatography, High Pressure Liquid; Humans; Polyamines; Putrescine; Scintillation Counting; Spermidine; Spermine; Tritium; Tumor Cells, Cultured | 1998 |
Spermine deficiency in Gy mice caused by deletion of the spermine synthase gene.
Topics: Animals; Base Sequence; Brain; Chromosome Mapping; DNA Primers; Exons; Gene Deletion; Humans; Hypophosphatemia; Infertility, Male; Liver; Male; Metabolic Diseases; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Molecular Sequence Data; Pancreas; Polymerase Chain Reaction; Pseudogenes; Putrescine; Spermidine; Spermine; Spermine Synthase; Stereotyped Behavior; X Chromosome | 1998 |
Polyamine uptake across the basolateral membrane of the enterocyte is mediated by a high-affinity carrier: a study using isolated basolateral membrane vesicles.
Topics: Animals; Basement Membrane; Biogenic Polyamines; Biological Transport, Active; In Vitro Techniques; Intestinal Mucosa; Putrescine; Rabbits; Spermidine; Spermine | 1998 |
Polyamine pools in HIV-infected cells.
Topics: Cell Line; Cytopathogenic Effect, Viral; Hematopoietic Stem Cells; HIV-1; Humans; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; T-Lymphocytes | 1998 |
Significant increases in the steady states of putrescine and spermidine/spermine N1-acetyltransferase mRNA in HeLa cells accompanied by growth arrest.
Topics: Acetyltransferases; Cell Division; DNA; Gene Expression Regulation; HeLa Cells; Humans; Ornithine Decarboxylase; Polyamines; Putrescine; RNA Precursors; RNA, Messenger; Spermidine; Spermine | 1998 |
The effect of acylated polyamine derivatives on polyamine uptake mechanism, cell growth, and polyamine pools in Escherichia coli, and the pursuit of structure/activity relationships.
Topics: Acylation; Bacterial Proteins; Biological Transport; Carrier Proteins; Escherichia coli; Escherichia coli Proteins; Kinetics; Membrane Transport Proteins; Models, Molecular; Periplasmic Binding Proteins; Polyamines; Protein Conformation; Putrescine; Spermidine; Spermine; Structure-Activity Relationship | 1998 |
Putrescine-stimulated intracellular Ca2+ release for invasiveness of rat ascites hepatoma cells.
Topics: Animals; Ascites; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Eflornithine; Enzyme Inhibitors; Liver Neoplasms, Experimental; Membrane Fluidity; Microscopy, Electron, Scanning; Neoplasm Invasiveness; Putrescine; Rats; Spermidine; Spermine; Tumor Cells, Cultured | 1998 |
Structural specificity of polyamines and polyamine analogues in the protection of DNA from strand breaks induced by reactive oxygen species.
Topics: Antineoplastic Agents; Antioxidants; Bacteriophage phi X 174; Biogenic Polyamines; Copper; DNA Damage; Hydrogen Peroxide; Polyamines; Putrescine; Reactive Oxygen Species; Spermidine; Spermine; Structure-Activity Relationship | 1998 |
Preserved induction of long-term potentiation in the stratum radiatum in the CA1 field of hippocampal slices from transgenic mice overexpressing ornithine decarboxylase and overproducing putrescine.
Topics: Animals; Chromatography, High Pressure Liquid; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred Strains; Mice, Transgenic; Ornithine Decarboxylase; Putrescine; Reference Values; Spermidine; Spermine; Synaptic Transmission | 1998 |
External action of di- and polyamines on maxi calcium-activated potassium channels: an electrophysiological and molecular modeling study.
Topics: Animals; Cadaverine; Cell Membrane; Diamines; Kinetics; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Models, Molecular; Molecular Conformation; Pituitary Neoplasms; Polyamines; Potassium Channels; Potassium Channels, Calcium-Activated; Protein Conformation; Putrescine; Spermidine; Spermine; Structure-Activity Relationship; Tetraethylammonium; Tumor Cells, Cultured | 1998 |
Polyamines regulate expression of the neoplastic phenotype in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Apoptosis; Carcinoma, Papillary; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Eflornithine; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ornithine Decarboxylase; Polyamines; Putrescine; Skin; Skin Neoplasms; Spermidine; Spermine | 1998 |
Polyamine inhibition of estrogen receptor (ER) DNA-binding and ligand-binding functions.
Topics: Breast; Breast Neoplasms; Cells, Cultured; DNA; Estradiol; Female; Humans; Polyamines; Putrescine; Receptors, Estrogen; Spermidine; Spermine; Transcriptional Activation; Tumor Cells, Cultured | 1998 |
Studies on human porin. XVI: Polyamines reduce the voltage dependence of human VDAC in planar lipid bilayers--spermine and spermidine inducing asymmetric voltage gating on the channel.
Topics: Humans; Ion Channel Gating; Ion Channels; Lipid Bilayers; Membrane Potentials; Membrane Proteins; p-Methoxy-N-methylphenethylamine; Polyamines; Porins; Spermidine; Spermine; Voltage-Dependent Anion Channels | 1998 |
A 1H/13C inverse 2D method for the analysis of the polyamines putrescine, spermidine and spermine in cell extracts and biofluids.
Topics: Animals; Body Fluids; Carbon Isotopes; Glioma; Hydrogen; Nuclear Magnetic Resonance, Biomolecular; Polyamines; Putrescine; Rats; Spermidine; Spermine; Tumor Cells, Cultured | 1998 |
Induction of spermidine/spermine N1-acetyltransferase by interferon type I in cells of hematopoietic origin.
Topics: Acetyltransferases; Base Sequence; Blotting, Northern; Burkitt Lymphoma; Cell Line; Enzyme Induction; Gene Expression Regulation, Enzymologic; Hematopoietic Stem Cells; Humans; Interferon Type I; Molecular Sequence Data; Spermidine; Spermine; Tumor Cells, Cultured | 1998 |
Oxidative degradation of polyamines in rat pancreatic hypertrophy.
Topics: Administration, Oral; Animals; Hypertrophy; Male; Organ Size; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Pancreas; Phytohemagglutinins; Polyamine Oxidase; Polyamines; Putrescine; Rats; Spermidine; Spermine; Substrate Specificity | 1998 |
Sensitization of tnf-induced apoptosis with polyamine synthesis inhibitors in different human and murine tumour cell lines.
Topics: Amidines; Animals; Antineoplastic Agents; Apoptosis; Eflornithine; Enzyme Inhibitors; Fas Ligand Protein; Granulocyte-Macrophage Colony-Stimulating Factor; HeLa Cells; Humans; Indans; Membrane Glycoproteins; Mice; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine; T-Lymphocytes; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Spermine/spermidine is expressed by retinal glial (Müller) cells and controls distinct K+ channels of their membrane.
Topics: Adolescent; Animals; Calcium; Enzyme Induction; Eye Proteins; Gene Expression Regulation; Guinea Pigs; Humans; Ion Transport; Magnesium; Male; Ornithine Decarboxylase; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rabbits; Retina; Spermidine; Spermine; Swine | 1998 |
DNA bending by small, mobile multivalent cations.
Topics: Base Sequence; Calcium; Cations; Crystallography, X-Ray; DNA; Elasticity; Kinetics; Magnesium; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Putrescine; Sodium; Solutions; Spermidine; Spermine; Static Electricity | 1998 |
A novel technique for visualizing the intracellular localization and distribution of transported polyamines in cultured pulmonary artery smooth muscle cells.
Topics: Animals; Cattle; Cells, Cultured; Fluorescein; Microscopy, Confocal; Muscle, Smooth, Vascular; Pulmonary Artery; Spermidine; Spermine | 1998 |
Determination of polyamines in human prostate by high-performance liquid chromatography with fluorescence detection.
Topics: Chromatography, High Pressure Liquid; Dansyl Compounds; Humans; Male; Prostate; Putrescine; Sensitivity and Specificity; Spectrometry, Fluorescence; Spermidine; Spermine; Temperature; Time Factors | 1998 |
Polyamine-stimulated binding of diamine oxidase to DNA.
Topics: Amine Oxidase (Copper-Containing); Animals; Cattle; DNA; DNA, Single-Stranded; Humans; Putrescine; Spermidine; Spermine; Stimulation, Chemical | 1998 |
Effect of different inhibitors on phospholipase C activity in Catharanthus roseus transformed roots.
Topics: Copper; Inositol 1,4,5-Trisphosphate; Neomycin; Nickel; Phosphatidylinositol 4,5-Diphosphate; Plant Roots; Plants; Protein Synthesis Inhibitors; Putrescine; Rhizobium; Signal Transduction; Spermidine; Spermine; Type C Phospholipases; Zinc | 1998 |
Trypanosoma cruzi has not lost its S-adenosylmethionine decarboxylase: characterization of the gene and the encoded enzyme.
Topics: Adenosylmethionine Decarboxylase; Amino Acid Sequence; Animals; Base Sequence; Blotting, Southern; Chromosome Mapping; DNA, Protozoan; Enzyme Inhibitors; Escherichia coli; Gene Expression; Genes, Protozoan; Kinetics; Mitoguazone; Molecular Sequence Data; Putrescine; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Spermidine; Spermine; Trypanosoma cruzi | 1998 |
Reaffirmation that metabolism of polyamines by bovine plasma amine oxidase occurs strictly at the primary amino termini.
Topics: Acrolein; Aldehydes; Amine Oxidase (Copper-Containing); Amines; Ammonia; Animals; Blood Proteins; Cattle; Magnetic Resonance Spectroscopy; Metalloproteins; Molecular Structure; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Propylamines; Spermidine; Spermine | 1998 |
L-Arginine inhibits vasopressin-stimulated mesangial cell Ca2+.
Topics: Animals; Arginine; Arginine Vasopressin; Calcium; Cell Line, Transformed; Cells, Cultured; Glomerular Mesangium; Guanidine; Mice; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine | 1998 |
A polyamine pathway-mediated mitogenic mechanism in enterochromaffin-like cells of Mastomys.
Topics: Animals; Cell Division; Cells, Cultured; DNA; Eflornithine; Enterochromaffin-like Cells; Gastric Mucosa; Gastrins; Muridae; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Transforming Growth Factor alpha | 1998 |
Digestion of 125I-labelled plasmin-derived fibrin degradation products by neutrophil lysosomal enzymes.
Topics: Antibodies, Monoclonal; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinolysin; Humans; Iodine Radioisotopes; Isoelectric Point; Lysosomes; Molecular Weight; Neutrophils; Reducing Agents; Sodium Dodecyl Sulfate; Spermidine; Spermine; Time Factors | 1998 |
Poly(L-lysine)-graft-dextran copolymer: amazing effects on triplex stabilization under physiological pH and ionic conditions (in vitro).
Topics: Cations, Monovalent; Dextrans; DNA; Hydrogen-Ion Concentration; Nucleic Acid Conformation; Polylysine; Potassium; Purines; Sodium; Spermidine; Spermine | 1998 |
Chronic exposure to ozone and nitric acid vapor results in increased levels of rat pulmonary putrescine.
Topics: Air Pollutants; Animals; Body Weight; Lung; Male; Nitric Acid; Ozone; Putrescine; Rats; Rats, Inbred F344; Spermidine; Spermine | 1998 |
Changes in biogenic amines and microbiological analysis in albacore (Thunnus alalunga) muscle during frozen storage.
Topics: Animals; Biogenic Amines; Cadaverine; Enterobacteriaceae; Food Preservation; Freezing; Histamine; Putrescine; Spermidine; Spermine; Tuna | 1998 |
Effects of polyamines and calcium and sodium ions on smooth muscle cytoskeleton-associated phosphatidylinositol (4)-phosphate 5-kinase.
Topics: Acrylic Resins; Adenosine Triphosphate; Animals; Anticoagulants; Calcium; Cell Fractionation; Cytoskeleton; Detergents; Ethanolamines; Heparin; Hydrogen-Ion Concentration; Intracellular Membranes; Magnesium; Muscle, Smooth; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphatidylserines; Phosphotransferases (Alcohol Group Acceptor); Polyamines; Potassium; Protein Binding; Putrescine; Sarcolemma; Sodium; Spermidine; Spermine; Substrate Specificity; Swine | 1998 |
Epidermal ornithine decarboxylase and polyamines in mice exposed to 50 Hz magnetic fields and UV radiation.
Topics: Analysis of Variance; Animals; Electromagnetic Fields; Female; Mice; Mice, Transgenic; Ornithine Decarboxylase; Polyamines; Putrescine; Skin; Spermidine; Spermine; Ultraviolet Rays | 1998 |
Effect of polyamine analogues on hypusine content in JURKAT T-cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Biological Transport; Cell Division; Chromatography, High Pressure Liquid; Dansyl Compounds; Enzyme Inhibitors; Humans; Jurkat Cells; Leukemia L1210; Lysine; Ornithine Decarboxylase Inhibitors; Spermidine; Spermine; Tumor Cells, Cultured | 1998 |
Phencyclidine-like discriminative stimulus effects of polyamine modulators of N-methyl-D-aspartate receptor activity in rats.
Topics: Animals; Biguanides; Discrimination Learning; Male; Motivation; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology; Spermidine; Spermine | 1998 |
NG-hydroxy-L-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms.
Topics: Animals; Aorta; Arginase; Arginine; Caco-2 Cells; Cell Division; Coculture Techniques; DNA; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Donors; Ornithine; Ornithine Decarboxylase; Oxadiazoles; Polyamines; Putrescine; Quinoxalines; Rats; Spermidine; Spermine; Thymidine; Triazenes; Urea | 1998 |
Complex polyamine effects on [3H]MDL 105,519 binding to the NMDA receptor glycine site.
Topics: Aminoquinolines; Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glycine; Indoles; Kynurenic Acid; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Tritium | 1998 |
Activity-dependent modulation of glutamate receptors by polyamines.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cells, Cultured; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ion Channel Gating; Ions; Kainic Acid; Kidney; Kinetics; Membrane Potentials; Neuronal Plasticity; Patch-Clamp Techniques; Phenols; Polyamines; Receptors, AMPA; Receptors, Kainic Acid; Spermidine; Spermine | 1998 |
Antitumor efficacy of N1,N11-diethylnorspermine on a human bladder tumor xenograft in nude athymic mice.
Topics: Animals; Antineoplastic Agents; Carcinoma, Transitional Cell; Cell Division; Cell Survival; Humans; Mice; Mice, Nude; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1997 |
Polyamines and paraquat toxicity in Arabidopsis thaliana.
Topics: Arabidopsis; Kinetics; Paraquat; Polyamines; Putrescine; Spermidine; Spermine | 1998 |
Chromatin proteins surrounding the d(G-T)n repeats and polyamine influence as revealed by photoaffinity labeling with reactive pd(A-C)6 derivatives.
Topics: Cell Nucleus; Chromatin; Chromosomal Proteins, Non-Histone; Deoxyribonucleotides; DNA; DNA, Single-Stranded; G1 Phase; HeLa Cells; Humans; Molecular Weight; Nucleic Acid Conformation; Photoaffinity Labels; Polyamines; S Phase; Single-Strand Specific DNA and RNA Endonucleases; Spermidine; Spermine | 1998 |
Inhibition of vacuolar ion channels by polyamines.
Topics: Chenopodiaceae; Cytoplasmic Granules; Ion Channels; Ion Transport; Patch-Clamp Techniques; Putrescine; Spermidine; Spermine | 1999 |
DNA unwinding in the CYC1 and DED1 yeast promoters.
Topics: Base Sequence; Binding Sites; Cell Cycle Proteins; Chlorides; Cytochrome c Group; Cytochromes c; DEAD-box RNA Helicases; DNA, Fungal; DNA, Superhelical; Fungal Proteins; Genes, Fungal; Molecular Sequence Data; Nucleic Acid Conformation; Promoter Regions, Genetic; RNA Helicases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Nucleic Acid; Single-Strand Specific DNA and RNA Endonucleases; Spermidine; Spermine; Structure-Activity Relationship | 1998 |
Comparative effects of TGFbeta on proliferation of 7- and 14-day-old chick embryo fibroblasts and lack of involvement of the ODC/PA system in the TGFbeta signaling pathway.
Topics: Animals; Cell Cycle; Cell Division; Cells, Cultured; Chick Embryo; Eflornithine; Enzyme Induction; Fibroblasts; Kinetics; Ornithine Decarboxylase; Polyamines; Putrescine; RNA; RNA, Messenger; S Phase; Signal Transduction; Skin; Spermidine; Spermine; Time Factors; Transcription, Genetic; Transforming Growth Factor beta | 1999 |
Human vascular endothelial cells incorporate spermine, but not spermidine or putrescine, into a 20 kDa protein.
Topics: Cell Line; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Homeostasis; Humans; Putrescine; Spermidine; Spermine | 1998 |
Radioprotection of human cell nuclear DNA by polyamines: radiosensitivity of chromatin is influenced by tightly bound spermine.
Topics: Binding Sites; Cell Line; Chromatin; DNA; DNA Damage; Gamma Rays; Humans; Polyamines; Putrescine; Radiation Tolerance; Radiation-Protective Agents; Spermidine; Spermine; Subcellular Fractions | 1999 |
[Chemical modification of eukaryotic cell chromatin, directed at d(GT)n-repeats of DNA].
Topics: Animals; Chromatin; Dinucleotide Repeats; DNA; HeLa Cells; Humans; Nucleic Acid Conformation; Rats; Spermidine; Spermine | 1998 |
Transgenic mice with activated polyamine catabolism due to overexpression of spermidine/spermine N1-acetyltransferase show enhanced sensitivity to the polyamine analog, N1, N11-diethylnorspermine.
Topics: Acetyltransferases; Animals; Enzyme Activation; Mice; Mice, Transgenic; Polyamines; Spermidine; Spermine | 1999 |
Differential effects of cyclopolyamines on the stability and conformation of triplex DNA.
Topics: Circular Dichroism; Cyclization; DNA; Dose-Response Relationship, Drug; Ligands; Nucleic Acid Conformation; Nucleic Acid Hybridization; Poly A; Poly T; Polyamines; Purines; Putrescine; Spermidine; Spermine; Temperature; Thermodynamics | 1999 |
2-deoxy-d-ribose-induced apoptosis in HL-60 cells is associated with the cell cycle progression by spermidine.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Cell Cycle; Deoxyribose; Eflornithine; Flow Cytometry; HL-60 Cells; Humans; Membrane Potentials; Mitochondria; Onium Compounds; Organophosphorus Compounds; Ornithine Decarboxylase Inhibitors; Oxidative Stress; Putrescine; Spermidine; Spermine | 1999 |
Inhibition of polyamine synthesis induces p53 gene expression but not apoptosis.
Topics: Animals; Apoptosis; Cattle; Cell Line; Culture Media; Eflornithine; Gene Expression Regulation; Genes, p53; Intestinal Mucosa; Kinetics; Polyamines; Putrescine; Rats; RNA, Messenger; Spermidine; Spermine; Transcription, Genetic; Tumor Suppressor Protein p53 | 1999 |
Characterization of the effects of polyamines on [125I]MK-801 binding to recombinant N-methyl-D-aspartate receptors.
Topics: Algorithms; Alternative Splicing; Animals; Brain; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fibroblasts; In Vitro Techniques; Membranes; Mice; Protein Binding; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Spermidine; Spermine | 1999 |
Multidrug resistance modifies polyamines uptake in P388 murine lymphoma cells: experimental and modeling approach.
Topics: Animals; Biological Transport; Drug Resistance, Multiple; Kinetics; Leukemia P388; Phenotype; Polyamines; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1999 |
Binding of spermidine and putrescine to energized liver mitochondria.
Topics: Animals; Binding Sites; Intracellular Membranes; Kinetics; Membrane Proteins; Mitochondria, Liver; Models, Chemical; Putrescine; Rats; Spermidine; Spermine | 1999 |
N8-acetyl spermidine protects rat cerebellar granule cells from low K+-induced apoptosis.
Topics: Animals; Animals, Newborn; Apoptosis; Cells, Cultured; Cerebellum; Cytarabine; Immunosuppressive Agents; Neurons; Potassium; Rats; Rats, Wistar; Spermidine; Spermine | 1999 |
Characterization of a novel spermidine/spermine acetyltransferase, BltD, from Bacillus subtilis.
Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Bacillus subtilis; Binding, Competitive; Coenzyme A; Diamines; Kinetics; Spermidine; Spermine; Substrate Specificity; Thermodynamics | 1999 |
Recombinant anti-polyamine antibodies: identification of a conserved binding site motif.
Topics: Amino Acid Sequence; Animals; Antibodies; Antibody Specificity; Binding Sites; Cross Reactions; Immunoglobulin Heavy Chains; Immunoglobulin Light Chains; Immunoglobulin Variable Region; Mice; Models, Molecular; Molecular Sequence Data; Ovalbumin; Polyamines; Putrescine; Recombinant Proteins; Spermidine; Spermine | 1999 |
Choice of vincristine or 6-mercaptopurine on the basis of polyamine level in tumor-bearing regions of the brain.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Chromatography, High Pressure Liquid; Male; Mercaptopurine; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Vincristine | 1999 |
Inhibition of polyamine synthesis arrests trichomonad growth and induces destruction of hydrogenosomes.
Topics: Animals; Biogenic Polyamines; Chromatography, High Pressure Liquid; Culture Media; Microscopy, Electron; Movement; Organelles; Putrescine; Spermidine; Spermine; Tritrichomonas foetus | 1999 |
Rectification of the olfactory cyclic nucleotide-gated channel by intracellular polyamines.
Topics: Animals; Binding Sites; Cyclic AMP; Electric Conductivity; Ion Channel Gating; Ion Channels; Membrane Potentials; Olfactory Receptor Neurons; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1999 |
Selectivity of polyamines on the stability of RNA-DNA hybrids containing phosphodiester and phosphorothioate oligodeoxyribonucleotides.
Topics: Binding, Competitive; DNA; Magnesium; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Organophosphates; Polyamines; Propylamines; RNA; Sodium; Spermidine; Spermine; Thionucleotides | 1999 |
Changes in endogenous polyamine levels are associated with differentiation in Dictyostelium discoideum.
Topics: Animals; Dictyostelium; Life Cycle Stages; Polyamines; Putrescine; Spermidine; Spermine | 1998 |
Polyamine co-matrices for matrix-assisted laser desorption/ionization mass spectrometry of oligonucleotides.
Topics: Acetophenones; Indicators and Reagents; Oligonucleotides; Polyamines; Polymers; Protons; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spermidine; Spermine; Thymidine Monophosphate | 1999 |
The polyamine oxidase inhibitor MDL-72,527 selectively induces apoptosis of transformed hematopoietic cells through lysosomotropic effects.
Topics: Animals; Apoptosis; bcl-X Protein; Cell Cycle; Cell Death; Cell Line, Transformed; Cell Survival; Cell Transformation, Neoplastic; Eflornithine; Hematopoietic Stem Cells; Humans; Interleukin-3; Kinetics; Lysosomes; Mice; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Proto-Oncogene Proteins c-bcl-2; Putrescine; Spermidine; Spermine | 1999 |
[3H]Spermine binding to synaptosomal membranes from the chick retina.
Topics: Animals; Chickens; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kinetics; Polyamines; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Retina; Spermidine; Spermine; Synaptosomes; Tritium | 1999 |
Asymmetric block of the plant vacuolar Ca(2+)-permeable channel by organic cations.
Topics: Calcium Channels; Chenopodiaceae; Cytosol; Ion Channel Gating; Membrane Potentials; Patch-Clamp Techniques; Putrescine; Quaternary Ammonium Compounds; Spermidine; Spermine; Tetraethylammonium; Tromethamine; Vacuoles | 1999 |
Bacteria genome fingerprinting by flow cytometry.
Topics: Bacterial Typing Techniques; Deoxyribonucleases, Type II Site-Specific; DNA Fingerprinting; DNA, Bacterial; Electrophoresis, Agar Gel; Flow Cytometry; Genome, Bacterial; Polyamines; Spermidine; Spermine; Staphylococcus aureus | 1999 |
Activation of nuclear factor kappaB by polyamines in breast cancer cells.
Topics: Breast Neoplasms; Circular Dichroism; Female; Guanidines; Humans; NF-kappa B; Polyamines; Protein Conformation; Putrescine; Spermidine; Spermine; Structure-Activity Relationship; Tumor Cells, Cultured | 1999 |
Polyamines as modulators of membrane fusion: aggregation and fusion of liposomes.
Topics: Cholesterol; Kinetics; Liposomes; Membrane Fusion; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Putrescine; Spermidine; Spermine | 1983 |
Polyamines regulate serine/threonine protein phosphatases in insulin-secreting cells.
Topics: Arginine; Eflornithine; Enzyme Activation; Enzyme Inhibitors; Histones; Humans; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Okadaic Acid; Pancreatic Neoplasms; Phosphoprotein Phosphatases; Phosphorylation; Polyamines; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 2000 |
Protection against radiation-induced degradation of DNA bases by polyamines.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Amidines; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Dimethyl Sulfoxide; DNA; DNA Damage; Dose-Response Relationship, Drug; Gamma Rays; Gas Chromatography-Mass Spectrometry; Guanine; Hydroxyl Radical; Oxidation-Reduction; Polyamines; Purines; Putrescine; Pyrimidines; Radiation-Protective Agents; Solutions; Spermidine; Spermine | 2000 |
Effects of the polyamine analogues N1-ethyl-N11-((cyclopropyl)methyl)-4,8-diazaundecane and N1-ethylN-11-((cycloheptyl)methyl)-4,8-diazaundecane in human prostate cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Division; DNA Fragmentation; Humans; Kinetics; Male; Polyamines; Propylamines; Prostatic Neoplasms; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 2000 |
Polyamine depletion delays apoptosis of rat intestinal epithelial cells.
Topics: Animals; Apoptosis; Camptothecin; Caspase 3; Caspases; Cell Adhesion; Cell Line; DNA Fragmentation; Eflornithine; Intestinal Mucosa; Kinetics; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 2000 |
Properties of a polyamine transporter regulated by antizyme.
Topics: Animals; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carrier Proteins; Cell Line; Indicators and Reagents; Kinetics; Mice; Onium Compounds; Organophosphorus Compounds; Ornithine Decarboxylase; Polyamines; Proteins; Putrescine; Recombinant Proteins; Spermidine; Spermine; Transfection | 2000 |
Polyamine metabolism in prostaglandin E2-treated human T lymphocytes.
Topics: Acetyltransferases; Biogenic Polyamines; Cyclic AMP; Dinoprostone; Humans; In Vitro Techniques; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine; T-Lymphocytes | 2000 |
Polyamines directly induce release of cytochrome c from heart mitochondria.
Topics: Animals; Apoptosis; Caspases; Cell Extracts; Chick Embryo; Cyclosporine; Cytochrome c Group; Cytosol; Dose-Response Relationship, Drug; Enzyme Activation; Female; Intracellular Membranes; Kinetics; Mitochondria, Heart; Myocardium; Permeability; Polyamines; Polylysine; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine | 2000 |
Conservation of polyamine regulation by translational frameshifting from yeast to mammals.
Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans; Conserved Sequence; Evolution, Molecular; Frameshift Mutation; Gene Deletion; Humans; Molecular Sequence Data; Mutagenesis; Polyamines; Protein Biosynthesis; Proteins; Putrescine; Schizosaccharomyces; Sequence Homology, Amino Acid; Spermidine; Spermine; Transcription, Genetic | 2000 |
The harpin ribozyme: the roles of ions in RNA cleavage.
Topics: Base Sequence; Binding Sites; Cations; Kinetics; Magnesium; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Polyamines; RNA; RNA, Catalytic; Spermidine; Spermine | 1999 |
Spatial distribution of spermine/spermidine content and K(+)-current rectification in frog retinal glial (Müller) cells.
Topics: Animals; Electric Conductivity; Electrophysiology; Immunohistochemistry; Neuroglia; Potassium Channels; Rana pipiens; Retina; Spermidine; Spermine; Staining and Labeling; Tissue Distribution | 2000 |
Polyamines are unevenly distributed within the rat and rabbit kidney.
Topics: Animals; Female; Kidney; Male; Polyamines; Putrescine; Rabbits; Rats; Rats, Sprague-Dawley; Sex Factors; Spermidine; Spermine; Tissue Distribution | 2000 |
Pancreatic exocrine secretions as a source of luminal polyamines in pigs.
Topics: Animals; Biogenic Polyamines; Diet; Disaccharidases; DNA; Female; Intestinal Absorption; Intestines; Milk; Pancreas; Pancreatic Juice; Putrescine; Spermidine; Spermine; Swine | 2000 |
Interleukin-1beta induces elevation of spermidine/spermine N1-acetyltransferase activity and an increase in the amount of putrescine in synovial adherent cells from patients with rheumatoid arthritis.
Topics: Acetyltransferases; Arthritis, Rheumatoid; Cell Division; Cells, Cultured; Collagenases; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression; Humans; Interleukin-1; Matrix Metalloproteinase 3; Putrescine; Spermidine; Spermine; Synovial Membrane | 2000 |
Promoter strength influences polyamine metabolism and morphogenic capacity in transgenic rice tissues expressing the oat adc cDNA constitutively.
Topics: Avena; Blotting, Northern; Blotting, Southern; Carboxy-Lyases; DNA, Complementary; Morphogenesis; Oryza; Plants, Genetically Modified; Polyamines; Promoter Regions, Genetic; Putrescine; Reverse Transcriptase Polymerase Chain Reaction; Spermidine; Spermine | 2000 |
Interaction of phospholipid bilayers with polyamines of different length.
Topics: Drug Stability; Electrochemistry; Lipid Bilayers; Membrane Potentials; Phosphatidylcholines; Polyamines; Putrescine; Spermidine; Spermine; Structure-Activity Relationship | 2000 |
Long-term portocaval shunt and changes in rat brain amine systems.
Topics: Animals; Atrophy; Biogenic Monoamines; Brain; Brain Chemistry; Dopamine; Hepatic Encephalopathy; Histamine; Liver; Male; Monoamine Oxidase; Portasystemic Shunt, Surgical; Rats; Rats, Wistar; Serotonin; Spermidine; Spermine | 1999 |
The synthesis and in vitro cytotoxic studies of novel bis-naphthalimidopropyl polyamine derivatives.
Topics: Antineoplastic Agents; Cell Division; Cell Survival; Cytotoxins; Drug Design; Humans; Imides; Molecular Structure; Polyamines; Putrescine; Quinolones; Spermidine; Spermine; Structure-Activity Relationship; Tumor Cells, Cultured | 2000 |
Polyamines in the gastro-intestinal tract of goat kids and in the regenerating ruminal epithelium of sheep.
Topics: Abomasum; Adenosylmethionine Decarboxylase; Animals; Animals, Newborn; Animals, Suckling; Digestive System; Duodenum; Female; Gastric Mucosa; Goats; Ornithine Decarboxylase; Polyamines; Putrescine; Radiography, Abdominal; Rumen; Sheep; Spermidine; Spermine | 2000 |
Prolactin and polyamine catabolism: specific effect on polyamine oxidase activity in rat thymus.
Topics: Acetyltransferases; Animals; Male; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Prolactin; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Spleen; Thymus Gland | 2000 |
ACAULIS5, an Arabidopsis gene required for stem elongation, encodes a spermine synthase.
Topics: Alleles; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Blotting, Northern; Cloning, Molecular; DNA Transposable Elements; DNA, Complementary; Escherichia coli; Models, Genetic; Molecular Sequence Data; Mutation; Phenotype; Plant Proteins; Promoter Regions, Genetic; Putrescine; Recombinant Proteins; Sequence Homology, Amino Acid; Spermidine; Spermine; Spermine Synthase; Time Factors; Tissue Distribution; Transgenes | 2000 |
Spermine differentially regulates the production of interleukin-12 p40 and interleukin-10 and suppresses the release of the T helper 1 cytokine interferon-gamma.
Topics: Animals; Gene Expression Regulation; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-12; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages, Peritoneal; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Subunits; Putrescine; RNA, Messenger; Spermidine; Spermine; Spleen; Th1 Cells; Transcription, Genetic | 2000 |
Effects of testosterone and 17, beta-estradiol on the polyamine metabolism in cultivated normal rat kidney epithelial cells.
Topics: Amine Oxidase (Copper-Containing); Animals; Blotting, Western; Cell Extracts; Cells, Cultured; Epithelial Cells; Estradiol; Female; Kidney; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Spermidine; Spermine; Testosterone | 2000 |
Structural basis of polyamine-DNA recognition: spermidine and spermine interactions with genomic B-DNAs of different GC content probed by Raman spectroscopy.
Topics: Animals; Base Composition; Cations, Divalent; Cattle; DNA; DNA, Bacterial; DNA, Fungal; Genome; Phosphates; Solutions; Spectrum Analysis, Raman; Spermidine; Spermine; Static Electricity; Structure-Activity Relationship | 2000 |
Partial purification and characterization of a phosphoprotein phosphatase from sperm plasma membrane.
Topics: Animals; Cell Membrane; Chromatography, High Pressure Liquid; Goats; Histones; Hydrogen-Ion Concentration; Iodine Radioisotopes; Male; Metals; Phosphates; Phosphoprotein Phosphatases; Phosphorylation; Proteins; Solubility; Spermatozoa; Spermidine; Spermine | 1999 |
Glycolytic enzymes in polyamine-treated bovine retina.
Topics: Animals; Cattle; Glycolysis; In Vitro Techniques; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Malondialdehyde; Polyamines; Putrescine; Retina; Spermidine; Spermine | 2000 |
Polyamines decrease Ca(2+) sensitivity of tension and increase rates of activation in skinned cardiac myocytes.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Magnesium; Myocardial Contraction; Myocardium; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine | 2000 |
Expression of the TGF-beta receptor gene and sensitivity to growth inhibition following polyamine depletion.
Topics: Activin Receptors, Type I; Animals; Cell Division; Cell Line; Eflornithine; Enzyme Inhibitors; Gene Expression; Humans; Intestine, Small; Laminin; Protein Serine-Threonine Kinases; Putrescine; Rats; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Spermidine; Spermine; Transforming Growth Factor beta; Tretinoin | 2000 |
Dietary fructans modulate polyamine concentration in the cecum of rats.
Topics: Animals; Cecum; Dietary Carbohydrates; Fructans; Male; Oligosaccharides; Polyamines; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine | 2000 |
Melatonin attenuates the changes in polyamine levels induced by systemic kainate administration in rat brains.
Topics: Animals; Brain; Cerebral Cortex; Chromatography, High Pressure Liquid; Hippocampus; Kainic Acid; Male; Melatonin; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Seizures; Spermidine; Spermine | 2000 |
Polyamine uptake in cultured astrocytes: characterization and modulation by protein kinases.
Topics: Animals; Astrocytes; Binding, Competitive; Biogenic Polyamines; Biological Transport; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Ion Transport; Ionophores; Mice; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Putrescine; Sodium; Sodium-Potassium-Exchanging ATPase; Spermidine; Spermine; Temperature; Tetradecanoylphorbol Acetate | 2000 |
Modulation of potassium channels in the hearts of transgenic and mutant mice with altered polyamine biosynthesis.
Topics: Animals; Cadaverine; Cells, Cultured; Disease Models, Animal; Hypophosphatemia, Familial; Ion Transport; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Myocardium; Ornithine Decarboxylase; Patch-Clamp Techniques; Polyamines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Promoter Regions, Genetic; Putrescine; Recombinant Fusion Proteins; Spermidine; Spermine; Spermine Synthase | 2000 |
Inward potassium channel in guard cells as a target for polyamine regulation of stomatal movements.
Topics: Adaptation, Physiological; Cadaverine; Chromatography, High Pressure Liquid; Fabaceae; Nicotiana; Patch-Clamp Techniques; Plant Leaves; Plant Proteins; Plants, Genetically Modified; Plants, Medicinal; Plants, Toxic; Polyamines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Putrescine; Spermidine; Spermine | 2000 |
Novel lysine-spermine conjugate inhibits polyamine transport and inhibits cell growth when given with DFMO.
Topics: Animals; Antineoplastic Agents; Biological Transport; Breast Neoplasms; Cell Division; Eflornithine; Female; Humans; Indicators and Reagents; Kinetics; Lysine; Male; Melanoma; Mice; Mice, Nude; Molecular Structure; Polyamines; Prostatic Neoplasms; Spermidine; Spermine; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays | 2000 |
Contrasting effects of ethylene perception and biosynthesis inhibitors on germination and seedling growth of barley (Hordeum vulgare L.).
Topics: Ethylenes; Germination; Hordeum; Plant Growth Regulators; Spermidine; Spermine | 2000 |
Screening for modulators of spermine tolerance identifies Sky1, the SR protein kinase of Saccharomyces cerevisiae, as a regulator of polyamine transport and ion homeostasis.
Topics: Adenosine Triphosphatases; Biological Transport; Cation Transport Proteins; Cell Division; Drug Resistance, Microbial; Focal Adhesion Protein-Tyrosine Kinases; Fungal Proteins; Genetic Complementation Test; Homeostasis; Ions; Kinetics; Lithium Chloride; Mutation; Osmotic Pressure; Phenotype; Polyamines; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proton-Translocating ATPases; Putrescine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Spermidine; Spermine | 2001 |
Polycations induce the release of soluble intermembrane mitochondrial proteins.
Topics: Adenylate Kinase; Aminoglycosides; Animals; Cardiolipins; Cytochrome c Group; Intracellular Membranes; Melitten; Membrane Proteins; Mice; Mitochondria, Liver; Oxygen Consumption; Permeability; Phospholipids; Polyamines; Polyelectrolytes; Spermidine; Spermine | 2001 |
DNA condensation in two dimensions.
Topics: Bacteriophage lambda; Cations, Divalent; Chlorides; Cobalt; DNA; DNA, Viral; Fatty Acids, Monounsaturated; Lipid Bilayers; Magnesium Chloride; Manganese Compounds; Models, Molecular; Nucleic Acid Conformation; Phosphatidylcholines; Quaternary Ammonium Compounds; Spermidine; Spermine | 2000 |
Polyamine regulation of ornithine decarboxylase and its antizyme in intestinal epithelial cells.
Topics: Animals; Cell Line; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Fetal Proteins; Intestines; Mitoguazone; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine | 2001 |
Nitric oxide synthase inhibition promotes carcinogen-induced preneoplastic changes in the colon of rats.
Topics: Adenosylmethionine Decarboxylase; Animals; Azoxymethane; Biogenic Polyamines; Blood Pressure; Body Weight; Carcinogens; Colon; Cyclic GMP; Enzyme Inhibitors; Heart Rate; Intestinal Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ornithine Decarboxylase; Precancerous Conditions; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine | 2000 |
Binding sites of the polyamines putrescine, cadaverine, spermidine and spermine on A- and B-DNA located by simulated annealing.
Topics: Base Sequence; Binding Sites; Biogenic Polyamines; Cadaverine; Computer Simulation; DNA; Drug Stability; Hydrogen Bonding; In Vitro Techniques; Models, Molecular; Nucleic Acid Conformation; Polydeoxyribonucleotides; Putrescine; Spermidine; Spermine; Thermodynamics | 2000 |
Fourier transform Raman study of the structural specificities on the interaction between DNA and biogenic polyamines.
Topics: Animals; Binding Sites; Biogenic Polyamines; Biophysical Phenomena; Biophysics; Cattle; Deuterium Oxide; DNA; Fourier Analysis; In Vitro Techniques; Models, Molecular; Putrescine; Solutions; Spectrum Analysis, Raman; Spermidine; Spermine; Water | 2001 |
Histamine prevents polyamine accumulation in mouse C57.1 mast cell cultures.
Topics: Acetyltransferases; Agmatine; Animals; Biological Transport; Bone Marrow Cells; Cell Division; Cell Line; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Histamine; Kinetics; Mast Cells; Mice; Mice, Inbred C57BL; Ornithine Decarboxylase; Polyamines; Putrescine; Serotonin; Spermidine; Spermine; Time Factors | 2001 |
Blood polyamine levels after oral ornithine load, a diagnostic marker of hyperproliferative premalignant and malignant stages in a model of colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Biotransformation; Body Weight; Cell Division; Chromatography, High Pressure Liquid; Colon; Colonic Neoplasms; Colonic Polyps; Disease Progression; Fasting; Hyperplasia; Male; Neoplasm Proteins; Ornithine; Ornithine Decarboxylase; Polyamines; Precancerous Conditions; Putrescine; Rats; Rats, Wistar; Sensitivity and Specificity; Spermidine; Spermine | 2000 |
Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents.
Topics: Animals; Binding, Competitive; Combinatorial Chemistry Techniques; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; NADH, NADPH Oxidoreductases; Polyamines; Spermidine; Spermine; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi | 2001 |
Polyamines in pancreatic islets of obese-hyperglycemic (ob/ob) mice of different ages.
Topics: Age Factors; Animals; Cells, Cultured; DNA; Enzyme Inhibitors; Female; Insulin; Islets of Langerhans; Male; Mice; Mice, Obese; Nucleic Acid Synthesis Inhibitors; Obesity; Polyamines; Spermidine; Spermine; Thinness | 2001 |
Spermine increases the active and passive transport across the alveolar epithelium in situ: effect of thiol reagents.
Topics: Amiloride; Animals; Biological Transport; Biological Transport, Active; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane Permeability; Ethylmaleimide; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ion Channel Gating; Mannitol; Mersalyl; Phosphatidylinositols; Pulmonary Alveoli; Putrescine; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Second Messenger Systems; Spermidine; Spermine; Sulfhydryl Compounds; Thimerosal | 2001 |
Cytoplasmic polyamines as permeant blockers and modulators of the voltage-gated sodium channel.
Topics: Amino Acid Substitution; Animals; Binding Sites; Cell Line; Cytoplasm; Heparin; Humans; Ion Channel Gating; Kinetics; Lysine; Membrane Potentials; Models, Biological; Muscle, Skeletal; Mutagenesis, Site-Directed; Rats; Recombinant Proteins; Sodium Channels; Spermidine; Spermine; Transfection | 2001 |
Effects of polyamines on DNA synthesis using various subcellular DNA polymerases extracted from normal rat liver, tumour-bearing rat liver, and tumour cells.
Topics: Animals; Cadaverine; Cytoplasm; DNA; DNA-Directed DNA Polymerase; Dose-Response Relationship, Drug; Liver; Liver Neoplasms; Mitochondria; Polyamines; Putrescine; Rats; Spermidine; Spermine; Time Factors; Tumor Cells, Cultured | 2001 |
Effect of N8-acetylspermidine deacetylase inhibition on the growth of L1210 cells.
Topics: Amidohydrolases; Animals; Cell Division; Chromatography, High Pressure Liquid; Diamines; Drug Interactions; Enzyme Inhibitors; Leukemia L1210; Mice; Polyamines; Putrescine; Spermidine; Spermine | 1999 |
Polyamine cytotoxicity in the presence of bovine serum amine oxidase.
Topics: 3T3 Cells; Acrolein; Aldehydes; Amine Oxidase (Copper-Containing); Animals; Cattle; Hydrogen Peroxide; Mice; Spermidine; Spermine | 2001 |
Methyl jasmonate upregulates biosynthetic gene expression, oxidation and conjugation of polyamines, and inhibits shoot formation in tobacco thin layers.
Topics: Acetates; Adenosylmethionine Decarboxylase; Amine Oxidase (Copper-Containing); Blotting, Northern; Carboxy-Lyases; Chromatography, Thin Layer; Culture Techniques; Cyclopentanes; Gene Expression Regulation, Plant; Morphogenesis; Nicotiana; Ornithine Decarboxylase; Oxidation-Reduction; Oxylipins; Plant Growth Regulators; Plant Shoots; Plants, Toxic; Polyamines; Putrescine; RNA, Plant; Spermidine; Spermine; Up-Regulation | 2001 |
NF-kappaB activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells.
Topics: Animals; Apoptosis; Cell Line; Cycloheximide; DNA Fragmentation; Eflornithine; G1 Phase; Intestinal Mucosa; Kinetics; NF-kappa B; Nucleosomes; Polyamines; Putrescine; Rats; Spermidine; Spermine; Staurosporine; Time Factors; Tumor Necrosis Factor-alpha | 2001 |
Polyamine and thiol metabolism in Trypanosoma granulosum: similarities with Trypanosoma cruzi.
Topics: Animals; Biogenic Polyamines; Cadaverine; Culture Media; Eflornithine; Glutathione; Methylhistidines; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine; Sulfhydryl Compounds; Tritium; Trypanosoma; Trypanosoma cruzi | 2001 |
Chemical, microbiological, and AromaScan evaluation of mahi-mahi fillets under various storage conditions.
Topics: Animals; Biogenic Amines; Cadaverine; Chromatography, Gas; Colony Count, Microbial; Electrophoresis, Capillary; Fish Products; Fishes; Food Preservation; Histamine; Odorants; Putrescine; Quality Control; Spermidine; Spermine; Temperature; Time Factors | 2001 |
X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid.
Topics: Adenosine; Crystallography, X-Ray; DNA, Catalytic; Hydrogen Bonding; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligoribonucleotides; RNA, Catalytic; Spermidine; Spermine | 2001 |
Polyamines in the basal ganglia of human brain. Influence of aging and degenerative movement disorders.
Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Basal Ganglia; Biogenic Polyamines; Female; Humans; Male; Middle Aged; Neurodegenerative Diseases; Putrescine; Spermidine; Spermine | 2001 |
Importance of the 3' untranslated region of ornithine decarboxylase mRNA in the translational regulation of the enzyme.
Topics: 3' Untranslated Regions; 5' Untranslated Regions; Animals; CHO Cells; Cricetinae; Down-Regulation; Enzyme Induction; Hypotonic Solutions; Ornithine Decarboxylase; Protein Biosynthesis; Putrescine; RNA, Messenger; Spermidine; Spermine | 2001 |
L-arginine-dependent suppression of apoptosis in Trypanosoma cruzi: contribution of the nitric oxide and polyamine pathways.
Topics: Agmatine; Animals; Apoptosis; Arginine; Cell Division; Cysteine Proteinase Inhibitors; DNA Fragmentation; DNA, Protozoan; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Polyamines; Putrescine; Spermidine; Spermine; Thymidine; Trypanosoma cruzi | 2001 |
A barley polyamine oxidase isoform with distinct structural features and subcellular localization.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Evolution, Molecular; Exons; Hordeum; Introns; Isoenzymes; Kinetics; Models, Molecular; Molecular Sequence Data; Oxidoreductases Acting on CH-NH Group Donors; Phylogeny; Polyamine Oxidase; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Spermidine; Spermine; Substrate Specificity; Transcription, Genetic; Zea mays | 2001 |
Dietary spermidine and spermine participate in the maturation of galactosyltransferase activity and glycoprotein galactosylation in rat small intestine.
Topics: Animal Feed; Animals; Animals, Newborn; Animals, Suckling; Chromatography, High Pressure Liquid; Galactosyltransferases; Glycoproteins; Glycosylation; Intestine, Small; Male; Microvilli; Milk; Polyamines; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Weaning | 2001 |
Raman study of the interaction between polyamines and a GC oligonucleotide.
Topics: Fourier Analysis; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Polyamines; Putrescine; Solutions; Spectrum Analysis, Raman; Spermidine; Spermine; Static Electricity; Water | 2001 |
Polyamine- and insulin-like growth factor-I-mediated proliferation of porcine uterine endometrial cells: a potential role for spermidine/spermine N(1)-acetyltransferase during peri-implantation.
Topics: Acetylation; Acetyltransferases; Animals; Blotting, Northern; Cell Division; DNA; Embryo Implantation; Endometrium; Enzyme Inhibitors; Female; Gene Expression; Gene Expression Regulation; Insulin-Like Growth Factor I; Mitogen-Activated Protein Kinases; Ornithine Decarboxylase; Phosphoinositide-3 Kinase Inhibitors; Polyamines; Pregnancy; RNA, Messenger; Spermidine; Spermine; Swine; Uterus | 2001 |
Antifungal activity of three spermidine conjugates.
Topics: Antifungal Agents; Ascomycota; Avena; Culture Media; Food Microbiology; Hordeum; Ornithine; Pollen; Putrescine; Spermidine; Spermine | 2001 |
Targeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy.
Topics: Adrenergic beta-Agonists; Animals; Atenolol; Blotting, Southern; Cadaverine; Cardiomegaly; Hypertrophy; Immunohistochemistry; Isoproterenol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Genetic; Myocardium; Ornithine Decarboxylase; Promoter Regions, Genetic; Putrescine; RNA, Messenger; Spermidine; Spermine; Tissue Distribution | 2001 |
Polyamine analogues inhibit the ubiquitination of spermidine/spermine N1-acetyltransferase and prevent its targeting to the proteasome for degradation.
Topics: Acetyltransferases; Animals; Arginine; Binding Sites; Cysteine Endopeptidases; DNA, Complementary; Dose-Response Relationship, Drug; Lysine; Multienzyme Complexes; Mutation; Plasmids; Polyamines; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Rabbits; Rats; Reticulocytes; Spermidine; Spermine; Time Factors; Ubiquitins | 2001 |
Short- and long-chain natural polyamines play specific roles in adult cricket neuroblast proliferation and neuron differentiation in vitro.
Topics: Animals; Brain; Cell Differentiation; Cell Division; Cells, Cultured; Gryllidae; Neurites; Neurons; Polyamines; Putrescine; Spermidine; Spermine | 2001 |
Protein translation during early cell divisions of sea urchin embryos regulated at the level of polypeptide chain elongation and highly sensitive to natural polyamines.
Topics: Animals; Cell Division; Cell-Free System; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Fertilization; Fertilization in Vitro; Kinetics; Peptides; Polyamines; Protein Biosynthesis; Protein Kinases; RNA; RNA, Messenger; Sea Urchins; Spermidine; Spermine; Time Factors | 2001 |
Concurrent overexpression of ornithine decarboxylase and spermidine/spermine N(1)-acetyltransferase further accelerates the catabolism of hepatic polyamines in transgenic mice.
Topics: Acetyltransferases; Animals; Chimera; Liver; Longevity; Mice; Mice, Transgenic; Ornithine Decarboxylase; Polyamines; Proteins; Spermidine; Spermine; Zinc | 2001 |
Hypertension in normotensive and hypertensive rats by spermine ingestion.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Heart Ventricles; Hypertension; Myocardium; Polyamines; Putrescine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spermidine; Spermine | 2001 |
Binding of spermidine to a unique protein in thin-layer tobacco tissue culture.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Culture Techniques; gamma-Aminobutyric Acid; Hydrolysis; Molecular Weight; Nicotiana; Plant Proteins; Plants, Toxic; Protein Binding; Putrescine; Spermidine; Spermine; Time Factors; Tritium | 1988 |
The polyamines of Xanthium strumarium and their response to photoperiod.
Topics: Light; Photoperiod; Plant Leaves; Plant Physiological Phenomena; Plants; Polyamines; Putrescine; Spermidine; Spermine; Time Factors | 1990 |
Polyamine metabolism and osmotic stress. I. Relation to protoplast viability.
Topics: Avena; Capsicum; Carboxy-Lyases; Datura stramonium; Fabaceae; Nicotiana; Ornithine Decarboxylase; Osmotic Pressure; Pisum sativum; Plant Leaves; Plants, Medicinal; Plants, Toxic; Polyamines; Protoplasts; Putrescine; Sorbitol; Spermidine; Spermine | 1986 |
Polyamine metabolism and osmotic stress. II. Improvement of oat protoplasts by an inhibitor of arginine decarboxylase.
Topics: Arginine; Avena; Carboxy-Lyases; Cell Division; Leucine; Ornithine Decarboxylase Inhibitors; Osmotic Pressure; Plant Leaves; Polyamines; Protoplasts; Putrescine; Spermidine; Spermine; Thymidine; Uridine | 1986 |
Cadmium-induced accumulation of putrescine in oat and bean leaves.
Topics: Arginine; Avena; Cadmium Chloride; Carboxy-Lyases; Dose-Response Relationship, Drug; Fabaceae; Ornithine Decarboxylase; Plant Leaves; Plants, Medicinal; Polyamines; Putrescine; Spermidine; Spermine | 1986 |
In vivo inhibition of polyamine biosynthesis and growth in tobacco ovary tissues.
Topics: Adenosylmethionine Decarboxylase; Arginine; Carboxy-Lyases; Eflornithine; Enzyme Inhibitors; Mitoguazone; Nicotiana; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Plants, Toxic; Polyamines; Putrescine; Spermidine; Spermine | 1985 |
Correlations between polyamine ratios and growth patterns in seedling roots.
Topics: Cadaverine; Cell Division; Cotyledon; Pisum sativum; Plant Roots; Polyamines; Putrescine; Solanum lycopersicum; Spermidine; Spermine; Vegetables; Zea mays | 1985 |
Changes in polyamine biosynthesis associated with postfertilization growth and development in tobacco ovary tissues.
Topics: Carboxy-Lyases; DNA, Plant; Nicotiana; Ornithine Decarboxylase; Plants, Toxic; Polyamines; Putrescine; Spermidine; Spermine | 1985 |
Polyamines and the integrity of the plant body.
Topics: Arginine; Carboxy-Lyases; Eflornithine; Ornithine Decarboxylase; Plant Cells; Plant Physiological Phenomena; Plants; Polyamines; Putrescine; Spermidine; Spermine | 1985 |
Use of phosphoimidazolide-activated guanosine to investigate the nucleophilicity of spermine and spermidine.
Topics: Chromatography, High Pressure Liquid; Guanosine Monophosphate; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Osmolar Concentration; Protons; Spermidine; Spermine | 1995 |
Arginase expression in peritoneal macrophages and increase in circulating polyamine levels in mice infected with Schistosoma mansoni.
Topics: Animals; Arginase; Cadaverine; Cells, Cultured; DNA Primers; Female; Macrophages, Peritoneal; Mice; Mice, Inbred CBA; Nitric Oxide Synthase; Nitrites; Polyamines; Protein Biosynthesis; Putrescine; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction; Schistosoma mansoni; Schistosomiasis mansoni; Spermidine; Spermine; Time Factors; Transcription, Genetic | 2001 |
Polyamine regulation of the rat pro-opiomelanocortin gene expression in AtT-20 cells.
Topics: Animals; Cell Division; Cell Line; Enzyme Inhibitors; Gene Expression; Mice; Mitoguazone; Polyamines; Pro-Opiomelanocortin; Putrescine; Rats; Receptors, Calcium-Sensing; Receptors, Cell Surface; Spermidine; Spermine | 2001 |
N-Benzylpolyamines as vectors of boron and fluorine for cancer therapy and imaging: synthesis and biological evaluation.
Topics: Animals; Biological Transport, Active; Boron Compounds; Boron Neutron Capture Therapy; Cell Line; DNA; Putrescine; Spermidine; Spermine; Structure-Activity Relationship; Tomography, Emission-Computed; Tumor Cells, Cultured | 2001 |
Novel approaches to polynuclear platinum pro-drugs. Selective release of cytotoxic platinum-spermidine species through hydrolytic cleavage of carbamates.
Topics: Animals; Antineoplastic Agents; Carbamates; Catalysis; Chromatography, High Pressure Liquid; Female; Humans; Hydrogen-Ion Concentration; Hydrolysis; Inhibitory Concentration 50; Leukemia L1210; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Organoplatinum Compounds; Ovarian Neoplasms; Polyamines; Prodrugs; Spermidine; Spermine; Stereoisomerism; Structure-Activity Relationship; Temperature; Tumor Cells, Cultured | 2001 |
Spermidine is essential for normal proliferation of trypanosomatid protozoa.
Topics: Animals; Crithidia fasciculata; Cyclohexylamines; Eflornithine; Enzyme Inhibitors; Ornithine Decarboxylase; Putrescine; Spermidine; Spermidine Synthase; Spermine; Trypanosoma cruzi | 2001 |
Polyamines in prostatic epithelial cells and adenocarcinoma; the effects of androgen blockade.
Topics: Adenocarcinoma; Androgen Antagonists; Eosinophils; Epithelial Cells; Humans; Immunohistochemistry; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Secretory Vesicles; Spermidine; Spermine | 2001 |
Polyamine metabolism and glutamate receptor agonists-mediated excitotoxicity in the rat brain.
Topics: Animals; Biogenic Polyamines; Biomarkers; Body Weight; Brain; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Frontal Lobe; Functional Laterality; Glutamic Acid; Hippocampus; Injections, Intraventricular; Male; Nerve Degeneration; Neurons; Neurotoxins; Putrescine; Rats; Rats, Wistar; Receptors, Glutamate; Spermidine; Spermine | 2001 |
Characterization of spermine uptake by Ehrlich tumour cells in culture.
Topics: Agmatine; Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Eflornithine; Kinetics; Osmolar Concentration; Spermidine; Spermine; Tumor Cells, Cultured | 2001 |
Polyamines as biochemical indicators of radiation injury.
Topics: Animals; Biomarkers; Bone Marrow Transplantation; Erythrocytes; Female; Gamma Rays; Humans; Male; Prostatic Neoplasms; Radiotherapy; Rats; Rats, Wistar; Spermidine; Spermine; Whole-Body Irradiation; X-Rays | 2001 |
Effects of the sap of the common oleander Nerium indicum (Apocyanaceae) on male fertility and spermatogenesis in the oriental tobacco budworm Helicoverpa assulta (Lepidoptera, Noctuidae).
Topics: Animals; Carboxy-Lyases; Fertility; Lepidoptera; Male; Nerium; Ornithine Decarboxylase; Plant Extracts; Putrescine; Spermatogenesis; Spermidine; Spermine; Testis | 2001 |
Effects of polyamines on the thermal stability and formation kinetics of DNA duplexes with abnormal structure.
Topics: Cations; Circular Dichroism; DNA; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; Polyamines; Spermidine; Spermine; Temperature | 2001 |
Simultaneous determination of endogenous and orally administered (15)N-labeled polyamines in rat organs.
Topics: Administration, Oral; Animals; Intestine, Small; Isotope Labeling; Kidney; Liver; Male; Mass Spectrometry; Nitrogen Isotopes; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine | 2002 |
Divalent cations and polyamines bind to loop 8 of 14-3-3 proteins, modulating their interaction with phosphorylated nitrate reductase.
Topics: 14-3-3 Proteins; Arabidopsis Proteins; Binding Sites; Calcium-Binding Proteins; Cations, Divalent; Magnesium; Mutagenesis, Site-Directed; Mutation; Nitrate Reductase; Nitrate Reductases; Phosphorylation; Plant Proteins; Polyamines; Protein Binding; Protein Conformation; Spermidine; Spermine; Tyrosine 3-Monooxygenase | 2002 |
Essential role of S-adenosylmethionine decarboxylase in mouse embryonic development.
Topics: Adenosylmethionine Decarboxylase; Animals; Embryonic and Fetal Development; Gene Targeting; Mice; Spermidine; Spermine | 2002 |
Regulation of ornithine decarboxylase and polyamine import by hypoxia in pulmonary artery endothelial cells.
Topics: Animals; Blotting, Western; Carbon Radioisotopes; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Gene Expression Regulation, Enzymologic; Hypertension, Pulmonary; Hypoxia; Muscle, Smooth, Vascular; Ornithine Decarboxylase; Polyamines; Proteins; Pulmonary Artery; Putrescine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spermidine; Spermine | 2002 |
Diamine oxidase is involved in H(2)O(2) production in the chalazal cells during barley grain filling.
Topics: Amine Oxidase (Copper-Containing); Hordeum; Hydrogen Peroxide; Isoelectric Focusing; Oxidoreductases Acting on CH-NH Group Donors; Peroxidase; Polyamine Oxidase; Polyamines; Potassium Iodide; Putrescine; Seeds; Spermidine; Spermine; Starch | 2002 |
Methyl jasmonate alters polyamine metabolism and induces systemic protection against powdery mildew infection in barley seedlings.
Topics: Acetates; Adenosylmethionine Decarboxylase; Amine Oxidase (Copper-Containing); Carboxy-Lyases; Cyclopentanes; Fungi; Hordeum; Immunity, Innate; Ornithine Decarboxylase; Oxylipins; Peroxidase; Phenylalanine Ammonia-Lyase; Plant Diseases; Plant Growth Regulators; Plants; Polyamines; Putrescine; Spermidine; Spermine | 2002 |
Differential distribution of spermidine/spermine-like immunoreactivity in neurons of the adult rat brain.
Topics: Animals; Brain; Female; Immunohistochemistry; Male; Neurons; Neurotransmitter Agents; Ornithine Decarboxylase; Rats; Rats, Inbred Lew; Spermidine; Spermine; Tissue Distribution | 2002 |
Voltage-dependent transient currents of human and rat 5-HT transporters (SERT) are blocked by HEPES and ion channel ligands.
Topics: Animals; Buffers; Carrier Proteins; Electrophysiology; HEPES; Humans; Ion Channels; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Oocytes; Rats; Serotonin; Serotonin Plasma Membrane Transport Proteins; Spermidine; Spermine; Time Factors; Xenopus laevis | 2002 |
Cytotoxic effects of metal complexes of biogenic polyamines. I. Platinum(II) spermidine compounds: prediction of their antitumour activity.
Topics: Antineoplastic Agents; Cell Division; Cell Survival; HeLa Cells; Humans; Molecular Structure; Organometallic Compounds; Organoplatinum Compounds; Spermidine; Spermine; Stereoisomerism; Structure-Activity Relationship | 2002 |
Quantitation of polyamines in hypothalamus and pituitary of female and male developing rats.
Topics: Agmatine; Animals; Chromatography, High Pressure Liquid; Eflornithine; Enzyme Inhibitors; Female; Hypothalamus; Male; Pituitary Gland; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Sex Characteristics; Spermidine; Spermine; Time Factors | 2002 |
Polyamine-dependent migration of retinal pigment epithelial cells.
Topics: Adenosylmethionine Decarboxylase; Cell Line; Cell Movement; Chromatography, High Pressure Liquid; Eflornithine; Enzyme Inhibitors; Humans; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pigment Epithelium of Eye; Putrescine; Spermidine; Spermine | 2002 |
Effect of immobilization stress on brain polyamine levels in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Acute Disease; Animals; Biogenic Polyamines; Brain; Chronic Disease; Frontal Lobe; Hippocampus; Hypertension; Hypothalamo-Hypophyseal System; Male; Putrescine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Restraint, Physical; Spermidine; Spermine; Stress, Physiological; Sympathetic Nervous System | 2002 |
A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464.
Topics: Antineoplastic Agents; Base Sequence; Binding Sites; Clinical Trials, Phase II as Topic; Cross-Linking Reagents; DNA; Fluorescence; Molecular Sequence Data; Molecular Weight; Organoplatinum Compounds; Platinum Compounds; Spermidine; Spermine | 2002 |
Regulation by polyamines of ornithine decarboxylase activity and cell division in the unicellular green alga Chlamydomonas reinhardtii.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Chlamydomonas reinhardtii; Light; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermidine Synthase; Spermine | 2002 |
Effects of exogenous diamines on the interaction between ectomycorrhizal fungi and adventitious root formation in Scots pine in vitro.
Topics: Basidiomycota; Cadaverine; In Vitro Techniques; Mycelium; Mycorrhizae; Pinus; Plant Roots; Putrescine; Seedlings; Spermidine; Spermine; Trees | 2002 |
Polyamine participation in the maturation of glycoprotein fucosylation, but not sialylation, in rat small intestine.
Topics: Amine Oxidase (Copper-Containing); Animal Feed; Animals; Animals, Suckling; beta-D-Galactoside alpha 2-6-Sialyltransferase; Enzyme Induction; Enzyme Inhibitors; Glycoproteins; Glycosylation; Intestinal Mucosa; Intestine, Small; Male; Microvilli; Milk; Ornithine; Protein Processing, Post-Translational; Proteins; Putrescine; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Sialyltransferases; Spermidine; Spermine; Transcription, Genetic; Weaning | 2002 |
Involvement of polyamines in root development at low temperature in the subantarctic cruciferous species Pringlea antiscorbutica.
Topics: Acclimatization; Agmatine; Antarctic Regions; Arginine; Brassicaceae; Carboxy-Lyases; Cold Temperature; Drug Interactions; Eflornithine; Germination; Glutarates; Mitoguazone; Ornithine Decarboxylase; Plant Roots; Plant Shoots; Polyamines; Putrescine; Seeds; Spermidine; Spermine | 2002 |
Biochemical effects and growth inhibition in MCF-7 cells caused by novel sulphonamido oxa-polyamine derivatives.
Topics: Amine Oxidase (Copper-Containing); Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Division; Cell Nucleus; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Microscopy, Phase-Contrast; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Spermidine; Spermine; Sulfonamides; Tumor Cells, Cultured | 2002 |
Polyamines and central nervous system injury: spermine and spermidine decrease following transient focal cerebral ischemia in spontaneously hypertensive rats.
Topics: Animals; Brain; Brain Injuries; Gerbillinae; Ischemic Attack, Transient; Putrescine; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Spermidine; Spermine | 2002 |
Comparative uptake of polyamines by prostate and non-prostate cancer cell lines.
Topics: Animals; Breast Neoplasms; Carbon Radioisotopes; Humans; Male; Ornithine; Polyamines; Prostatic Neoplasms; Putrescine; Radionuclide Imaging; Rats; Reproducibility of Results; Sensitivity and Specificity; Spermidine; Spermine; Tumor Cells, Cultured; Urogenital Neoplasms | 2002 |
Polyamine uptake is necessary for a normal biochemical maturation of astrocytes in culture.
Topics: Animals; Astrocytes; Biogenic Polyamines; Cell Differentiation; Cell Division; Cells, Cultured; Cerebellum; DNA; Down-Regulation; Eflornithine; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Mice; Mitoguazone; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine; Thymidine; Up-Regulation | 2002 |
Effect of infiltrated polyamines on polygalacturonase activity and chilling injury responses in zucchini squash (Cucurbita pepo L.).
Topics: Cold Temperature; Cucurbita; Cytoprotection; Dose-Response Relationship, Drug; Ion Transport; Polyamines; Polygalacturonase; Putrescine; Spermidine; Spermine | 2002 |
Transglutaminase-mediated polyamination of vasoactive intestinal peptide (VIP) Gln16 residue modulates VIP/PACAP receptor activity.
Topics: Amino Acid Sequence; Animals; Cells, Cultured; Cricetinae; Glutamine; Humans; Macrophages; Mice; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Polyamines; Rats; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Receptors, Vasoactive Intestinal Peptide; Receptors, Vasoactive Intestinal Peptide, Type II; Receptors, Vasoactive Intestinal Polypeptide, Type I; Spermidine; Spermine; Transglutaminases; Vasoactive Intestinal Peptide | 2002 |
Suppression of S-adenosylmethionine decarboxylase activity is a major cause for high-temperature inhibition of pollen germination and tube growth in tomato (Lycopersicon esculentum Mill.).
Topics: Adenosylmethionine Decarboxylase; Carboxy-Lyases; Cycloheximide; Dactinomycin; Endopeptidases; Enzyme Stability; Hot Temperature; Pollen; Polyamines; Putrescine; Solanum lycopersicum; Spermidine; Spermine; Time Factors | 2002 |
Role of endocytosis in the internalization of spermidine-C(2)-BODIPY, a highly fluorescent probe of polyamine transport.
Topics: Animals; Biological Transport; Boron Compounds; Cell Compartmentation; CHO Cells; Cricetinae; Endocytosis; Fluorescent Dyes; Focal Adhesion Protein-Tyrosine Kinases; Microscopy, Confocal; Mutation; Polyamines; Protein-Tyrosine Kinases; Putrescine; Spectrometry, Fluorescence; Spermidine; Spermine; Yeasts | 2002 |
The difference in the stimulation by putrescine of DNA synthesis using DNA polymerase extracts of normal rat liver or of tumour tissue or host liver from tumour-bearing rats.
Topics: Animals; Cadaverine; Cellulose; Centrifugation, Density Gradient; Chromatography; DNA; DNA-Directed DNA Polymerase; Dose-Response Relationship, Drug; Ethanolamines; Hot Temperature; Liver; Male; Polyamines; Putrescine; Rats; Ribonuclease T1; Spermidine; Spermine; Sucrose; Time Factors; Trypsin | 2002 |
Characterization of selected Spanish table wine samples according to their biogenic amine content from liquid chromatographic determination.
Topics: Analysis of Variance; Biogenic Monoamines; Cadaverine; Chromatography, High Pressure Liquid; Fermentation; Histamine; Putrescine; Spermidine; Spermine; Tyramine; Wine | 2002 |
Content of biogenic amines in a Chardonnay wine obtained through spontaneous and inoculated fermentations.
Topics: Biogenic Amines; Dimethylamines; Ethylamines; Fermentation; Hydrogen-Ion Concentration; Phenethylamines; Putrescine; Pyrrolidines; Saccharomyces cerevisiae; Spermidine; Spermine; Volatilization; Wine | 2002 |
Phase-change related epigenetic and physiological changes in Pinus radiata D. Don.
Topics: DNA Methylation; Pinus; Polyamines; Putrescine; Spermidine; Spermine; Time Factors | 2002 |
Expression of a heterologous S-adenosylmethionine decarboxylase cDNA in plants demonstrates that changes in S-adenosyl-L-methionine decarboxylase activity determine levels of the higher polyamines spermidine and spermine.
Topics: Adenosylmethionine Decarboxylase; Amine Oxidase (Copper-Containing); Carboxy-Lyases; Datura; DNA, Complementary; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genetic Complementation Test; Ornithine Decarboxylase; Oryza; Oxidoreductases Acting on CH-NH Group Donors; Plant Leaves; Plants, Genetically Modified; Polyamine Oxidase; Polyamines; Putrescine; Seeds; Spermidine; Spermine | 2002 |
A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism.
Topics: alpha-Amylases; Animals; Animals, Genetically Modified; Immunohistochemistry; Liver; Mice; Pancreatitis; Polyamines; Proliferating Cell Nuclear Antigen; Protein Binding; Rats; Regeneration; Spermidine; Spermine; Time Factors; Zinc | 2002 |
Polyamine structural effects on the induction and stabilization of liquid crystalline DNA: potential applications to DNA packaging, gene therapy and polyamine therapeutics.
Topics: Animals; Cattle; Crystallization; DNA; Genetic Therapy; Methenamine; Microscopy, Polarization; Nucleic Acid Conformation; Polyamines; Spermidine; Spermine; Structure-Activity Relationship; Thymus Gland | 2002 |
Cerebral distribution of polyamines in kainic acid-induced models of status epilepticus and ataxia in rats. Overproduction of putrescine and histological damage.
Topics: Analysis of Variance; Animals; Ataxia; Biogenic Polyamines; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Injections, Intraperitoneal; Injections, Intraventricular; Kainic Acid; Male; Motor Activity; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Status Epilepticus | 2002 |
Effects of aminooxy analogues of biogenic polyamines on aggregation and stability of calf thymus DNA.
Topics: Animals; Biogenic Polyamines; Cattle; Chemical Precipitation; Circular Dichroism; DNA; Hydrogen-Ion Concentration; Nucleic Acid Conformation; Sonication; Spermidine; Spermine; Stereoisomerism; Structure-Activity Relationship; Temperature | 2002 |
Moderate folate deficiency influences polyamine synthesis in rats.
Topics: Animals; Biogenic Polyamines; Brain; Folic Acid; Folic Acid Deficiency; Intestinal Mucosa; Liver; Male; Putrescine; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Spermidine; Spermine | 2002 |
Collagen sandwich culture affects intracellular polyamine levels of human hepatocytes.
Topics: Biogenic Polyamines; Cell Culture Techniques; Cell Differentiation; Cell Division; Cells, Cultured; Collagen; Extracellular Matrix; Hepatocytes; Humans; Putrescine; Spermidine; Spermine; Time Factors | 2002 |
The ability of cystamine to bind DNA.
Topics: Animals; Binding Sites; Biogenic Polyamines; Cattle; Chromatin; Cystamine; DNA; Ethidium; Nucleic Acid Conformation; Nucleic Acid Denaturation; Spermidine; Spermine; Thermodynamics | 2002 |
Cloning and characterization of multiple human polyamine oxidase splice variants that code for isoenzymes with different biochemical characteristics.
Topics: Alternative Splicing; Amino Acid Sequence; Cell Line; Cloning, Molecular; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Library; Humans; Kinetics; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Protein Biosynthesis; Protein Isoforms; Sequence Homology, Amino Acid; Spermidine; Spermine; Substrate Specificity; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Effect of spermine conjugation on the cytotoxicity and cellular transport of acridine.
Topics: Acridines; Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Cell Division; Cell Line; Cricetinae; DNA; Eflornithine; Mutation; Ornithine Decarboxylase Inhibitors; Spectrometry, Fluorescence; Spermidine; Spermine | 2002 |
Two enzyme-linked immunosorbent assay (ELISA) systems for N1,N8-diacetylspermidine and N1,N12-diacetylspermine using monoclonal antibodies.
Topics: Antibodies, Monoclonal; Antibody Formation; Enzyme-Linked Immunosorbent Assay; Humans; Spermidine; Spermine | 2002 |
Functional characterization of the human spermidine/spermine N(1)-acetyltransferase gene promoter.
Topics: 5' Flanking Region; Acetyltransferases; Blotting, Northern; DNA Footprinting; DNA-Binding Proteins; Dose-Response Relationship, Radiation; Electrophoretic Mobility Shift Assay; HeLa Cells; Humans; Point Mutation; Promoter Regions, Genetic; RNA, Messenger; Sp1 Transcription Factor; Spermidine; Spermine; Time Factors; Transcription Initiation Site; Transcription, Genetic; Up-Regulation | 2002 |
Cellular polyamines promote the aggregation of alpha-synuclein.
Topics: alpha-Synuclein; Binding Sites; Circular Dichroism; Cloning, Molecular; Escherichia coli; Humans; Microscopy, Atomic Force; Microscopy, Electron; Nerve Tissue Proteins; Parkinson Disease; Phosphoproteins; Protein Conformation; Putrescine; Recombinant Proteins; Spectrometry, Fluorescence; Spermidine; Spermine; Synucleins | 2003 |
Inhibition of enzymes of polyamine biosynthesis by substrate-like O-substituted hydroxylamines.
Topics: Adenosylmethionine Decarboxylase; Animals; Hydroxylamines; Liver; Mice; Molecular Conformation; Molecular Structure; Ornithine Decarboxylase Inhibitors; Polyamines; Rats; Spermidine; Spermine; Substrate Specificity | 2002 |
Modulation by polyamines of gamma-glutamyl transpeptidase activity and lactate production in cultured Sertoli cells from immature and adult regressed golden hamster.
Topics: Aging; Animals; Cells, Cultured; Cricetinae; Follicle Stimulating Hormone; gamma-Glutamyltransferase; Lactic Acid; Male; Photoperiod; Putrescine; Reproduction; Sertoli Cells; Spermidine; Spermine | 2002 |
Voltage-dependent blockade of connexin40 gap junctions by spermine.
Topics: Animals; Connexin 43; Connexins; Dose-Response Relationship, Drug; Electric Conductivity; Gap Junction alpha-5 Protein; Gap Junctions; Gene Transfer Techniques; Ion Channel Gating; Mice; Neuroblastoma; Rats; Recombinant Fusion Proteins; Sensitivity and Specificity; Spermidine; Spermine; Tumor Cells, Cultured | 2003 |
Polyamine metabolism is altered in unpollinated parthenocarpic pat-2 tomato ovaries.
Topics: Carboxy-Lyases; Eflornithine; Flowers; Fruit; Gibberellins; Mutation; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Reproduction; RNA, Plant; Solanum lycopersicum; Spermidine; Spermidine Synthase; Spermine; Triazoles | 2003 |
Effects of polyamines on organogenesis and somatic embryogenesis of Lycium barbarum calli.
Topics: Lycium; Polyamines; Putrescine; Spermidine; Spermine | 2001 |
Antioxidant effect of polyamines on erythrocyte cell membrane lipoperoxidation after free-radical damage.
Topics: Adult; Aged; Antioxidants; Dose-Response Relationship, Drug; Erythrocyte Membrane; Female; Humans; Hydrogen Peroxide; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Phytotherapy; Putrescine; Spermidine; Spermine; Thiobarbituric Acid Reactive Substances | 2003 |
Polyamine transport, accumulation, and release in brain.
Topics: Animals; Biogenic Polyamines; Biological Transport; Brain; Brain Chemistry; Cells, Cultured; Hippocampus; In Vitro Techniques; Male; Neuroglia; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Synaptic Vesicles; Synaptosomes | 2003 |
Reinvigoration of Pinus radiata is associated with partial recovery of juvenile-like polyamine concentrations.
Topics: Biogenic Polyamines; Chromatography, High Pressure Liquid; Pinus; Putrescine; Spermidine; Spermine; Trees | 2003 |
Copper(II) complexes with uridine, uridine 5'-monophosphate, spermidine, or spermine in aqueous solution.
Topics: Binding Sites; Copper; Hydrogen-Ion Concentration; Nucleic Acids; Solutions; Spectrum Analysis; Spermidine; Spermine; Uridine; Uridine Monophosphate | 2003 |
Changes in free polyamines and related enzymes during stipule and pod wall development in Pisum sativum.
Topics: Aging; Amine Oxidase (Copper-Containing); Carboxy-Lyases; Chlorophyll; DNA, Plant; Electric Conductivity; Gene Expression Regulation, Developmental; Ornithine Decarboxylase; Pisum sativum; Plant Proteins; Polyamines; Putrescine; RNA, Plant; Spermidine; Spermine | 2002 |
Ameliorative effects of histamine on 7-chlorokynurenic acid-induced spatial memory deficits in rats.
Topics: Animals; Excitatory Amino Acid Antagonists; Histamine; Kynurenic Acid; Male; Memory Disorders; Methylhistamines; Motor Activity; Polyamines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 2003 |
Tumor targeting of gene expression through metal-coordinated conjugation with dextran.
Topics: Animals; Chelating Agents; Dextrans; DNA; Electrophoresis; Gene Expression Regulation, Neoplastic; Genetic Therapy; Injections, Intravenous; Light; Metals; Mice; Microscopy, Fluorescence; Neoplasms; Pentetic Acid; Plasmids; Scattering, Radiation; Spermidine; Spermine; Zinc | 2003 |
Acrolein produced from polyamines as one of the uraemic toxins.
Topics: Acrolein; Biogenic Polyamines; Case-Control Studies; Cell Line; Cell Survival; Humans; Kidney Failure, Chronic; Nephritis; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Spermine; Uremia | 2003 |
Cloning, sequencing, and heterologous expression of the murine peroxisomal flavoprotein, N1-acetylated polyamine oxidase.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cattle; Cloning, Molecular; Escherichia coli; Flavoproteins; Gene Expression Regulation, Enzymologic; Kinetics; Mice; Molecular Sequence Data; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Peroxisomes; Polyamine Oxidase; RNA, Messenger; Species Specificity; Spermidine; Spermine | 2003 |
Polyvalent cations as permeant probes of MIC and TRPM7 pores.
Topics: Animals; Calcium Channels; Cation Transport Proteins; Cations; Cell Line; Cell Line, Tumor; Cell Membrane Permeability; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Electric Conductivity; Humans; Ion Channel Gating; Ion Channels; Jurkat Cells; Leukemia, Basophilic, Acute; Magnesium; Membrane Potentials; Membrane Proteins; Phenols; Polyamines; Putrescine; Rats; Spermidine; Spermine; TRPM Cation Channels | 2003 |
The polyamines spermine and spermidine protect proteins from structural and functional damage by AGE precursors: a new role for old molecules?
Topics: Animals; Antithrombin III; Carnosine; Cattle; Dimerization; Dose-Response Relationship, Drug; Drug Combinations; Electrophoresis, Polyacrylamide Gel; Glucose-6-Phosphatase; Glycation End Products, Advanced; Glyceraldehyde; Histones; Humans; Plasminogen; Pyruvaldehyde; Spermidine; Spermine; Ubiquitin | 2003 |
Caenorhabditis elegans S-adenosylmethionine decarboxylase is highly stimulated by putrescine but exhibits a low specificity for activator binding.
Topics: Adenosylmethionine Decarboxylase; Amino Acid Sequence; Animals; Blotting, Western; Caenorhabditis elegans; Catalysis; Conserved Sequence; Enzyme Activators; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Protein Processing, Post-Translational; Putrescine; Recombinant Proteins; Spermidine; Spermine; Stimulation, Chemical; Substrate Specificity | 2003 |
The influence of the brewing process on the formation of biogenic amines in beers.
Topics: Beer; Biogenic Amines; Cadaverine; Chromatography, High Pressure Liquid; Edible Grain; Fermentation; Food Analysis; Food Handling; Histamine; Phenethylamines; Putrescine; Spermidine; Spermine; Tryptamines; Tyramine; Zea mays | 2003 |
Rapid absorption of luminal polyamines in a rat small intestine ex vivo model.
Topics: Animals; Biological Transport; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Male; Polyamines; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine | 2003 |
Nitric oxide inhibits polyamine-induced apoptosis in the human extravillous trophoblast cell line SGHPL-4.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Catalase; Cell Line; Cysteine Proteinase Inhibitors; Humans; Nitric Oxide; Oxidation-Reduction; Poly(ADP-ribose) Polymerases; Polyamines; Putrescine; Spermidine; Spermine; Time Factors; Trophoblasts | 2003 |
Properties of purified recombinant human polyamine oxidase, PAOh1/SMO.
Topics: Enzyme Inhibitors; Humans; Molecular Structure; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Recombinant Proteins; Spermidine; Spermine; Substrate Specificity | 2003 |
Effects of exogenous polyamines on growth, toxicity, and toxin profile of dinoflagellate Alexandrium minutum.
Topics: Animals; Cadaverine; Dinoflagellida; Marine Toxins; Polyamines; Putrescine; Spermidine; Spermine | 2003 |
Bis(glutathionyl)spermine and other novel trypanothione analogues in Trypanosoma cruzi.
Topics: Animals; Chromatography, High Pressure Liquid; Glutathione; Kinetics; Mass Spectrometry; Models, Chemical; Polyamines; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spermidine; Spermine; Substrate Specificity; Sulfhydryl Compounds; Time Factors; Trypanosoma cruzi | 2003 |
Induction of phase 2 enzymes by serum oxidized polyamines through activation of Nrf2: effect of the polyamine metabolite acrolein.
Topics: Acrolein; Amine Oxidase (Copper-Containing); Animals; Antioxidants; Cell Line; Culture Media; DNA-Binding Proteins; Enzyme Induction; Enzyme Inhibitors; Enzymes; Guanidines; Keratinocytes; Mice; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidation-Reduction; Response Elements; RNA, Messenger; Signal Transduction; Spermidine; Spermine; Trans-Activators; Transcriptional Activation | 2003 |
Polyamines in cultured rabbit corneal cells.
Topics: Animals; Biogenic Polyamines; Cell Division; Cells, Cultured; Corneal Stroma; Dose-Response Relationship, Drug; Eflornithine; Endothelium, Corneal; Enzyme Inhibitors; Epithelium, Corneal; Fibroblasts; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Rabbits; Spermidine; Spermine; Time Factors | 2003 |
Polyamines reverse non-steroidal anti-inflammatory drug-induced toxicity in human colorectal cancer cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Division; Cell Membrane; Cell Survival; Colorectal Neoplasms; DNA Fragmentation; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Indoles; Intercalating Agents; Naproxen; Polyamines; Putrescine; Salicylates; Spermidine; Spermine; Sulindac; Tumor Cells, Cultured | 2003 |
Ectomycorrhizal fungal species and strains differ in their ability to produce free and conjugated polyamines.
Topics: Agaricales; Basidiomycota; Biogenic Polyamines; Cadaverine; Mycelium; Mycorrhizae; Species Specificity; Spermidine; Spermine | 2003 |
Inhibition of arterial thrombosis by polyamines in a canine coronary artery injury model.
Topics: Abdominal Injuries; Animals; Coronary Thrombosis; Coronary Vessels; Dogs; Drug Evaluation, Preclinical; Female; Gingival Hemorrhage; Hemorrhage; Male; Putrescine; Spermidine; Spermine | 2003 |
Vitreous polyamines spermidine, putrescine, and spermine in human proliferative disorders of the retina.
Topics: Adult; Aged; Biomarkers; Chromatography, High Pressure Liquid; Diabetic Retinopathy; Endothelial Growth Factors; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-8; Lymphokines; Middle Aged; Putrescine; Spermidine; Spermine; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vitreous Body | 2003 |
Lytic infection of pseudorabies virus in the presence of spermine, spermidine, or DFMO.
Topics: Animals; Biogenic Polyamines; Cell Line; Eflornithine; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Herpesvirus 1, Suid; Mice; Ornithine Decarboxylase Inhibitors; Promoter Regions, Genetic; Radioisotopes; Spermidine; Spermine; Transcription, Genetic; Transfection; Viral Plaque Assay; Viral Proteins | 2003 |
Effects of polyamines on histone polymerization.
Topics: Animals; Biopolymers; Calcium; Catalysis; Guinea Pigs; Histones; Polyamines; Putrescine; Spermidine; Spermine; Transglutaminases | 2003 |
Spermine oxidase: an amine oxidase with specificity for spermine and spermidine.
Topics: Amine Oxidase (Copper-Containing); Animals; Cattle; Deamination; Kinetics; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Sheep; Spermidine; Spermine; Substrate Specificity | 1953 |
[Oxidative deamidation of spermine and spermidine by bovine plasma].
Topics: Animals; Cattle; Oxidation-Reduction; Plasma; Spermidine; Spermine | 1954 |
Factors influencing the antibacterial action of spermine and spermidine on Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Humans; Spermidine; Spermine; Staphylococcal Infections; Staphylococcus aureus | 1955 |
The pharmacology of spermine and spermidine; distribution and excretion.
Topics: Amines; Biological Transport; Body Fluids; Humans; Spermidine; Spermine; Urine | 1956 |
Pharmacology of spermine and spermidine; some effects on animals and bacteria.
Topics: Amines; Bacteria; Escherichia coli; Kidney; Male; Micrococcus; Spermatozoa; Spermidine; Spermine; Staphylococcus aureus | 1956 |
[Determination of spermin, spermidine, and other biogenic amines after separation by paper electrophoresis, and their quantity in animal organs].
Topics: Amines; Animal Structures; Animals; Biogenic Amines; Electrophoresis, Paper; Humans; Spermidine; Spermine | 1957 |
Quantitative determination of putrescine, cadaverine, spermine and spermidine.
Topics: Amines; Cadaverine; Putrescine; Spermidine; Spermine | 1957 |
Formation of beta-alanine from spermine and spermidine by Pseudomonas aeruginosa.
Topics: Alanine; Amines; beta-Alanine; Biochemical Phenomena; Pseudomonas aeruginosa; Spermidine; Spermine | 1958 |
The biosynthesis of spermidine and spermine from putrescine and methionine.
Topics: Amines; Methionine; Putrescine; Spermidine; Spermine | 1958 |
The formation of spermidine from spermine by serum amine oxidase.
Topics: Monoamine Oxidase; Oxidoreductases; Spermidine; Spermine | 1960 |
Spermidine in the extraction of the deoxyribosyl-synthesizing system from T6r plus-infected Escherichia coli.
Topics: Bacteriophages; Enzymes; Escherichia coli; Spermidine; Spermine | 1962 |
Metabolism of polyamines by Staphylococcus.
Topics: Amines; Cadaverine; Polyamines; Putrescine; Spermidine; Spermine; Staphylococcus | 1962 |
STUDIES ON POLYAMINES. II. METABOLISM OF SPERMIDINE AND SPERMINE BY AMINE OXIDASE IN BEEF SERUM.
Topics: Amines; Animals; Blood Chemical Analysis; Cattle; Chromatography; Electrophoresis; Metabolism; Monoamine Oxidase; Oxidation-Reduction; Oxidoreductases; Polyamines; Research; Spectrum Analysis; Spermidine; Spermine | 1963 |
STUDIES ON THE DETERMINATION OF SPERMIDINE AND SPERMINE AND THEIR METABOLISM IN THE DEVELOPING CHICK EMBRYO.
Topics: Amines; Animals; Autoradiography; Carbon Isotopes; Chick Embryo; Chromatography; Coloring Agents; Electrophoresis; Ethionine; Histocytochemistry; Liver; Metabolism; Methionine; Ornithine; Rats; Research; Spermidine; Spermine; Staining and Labeling | 1963 |
EFFECT OF POLYAMINE STRUCTURE ON GROWTH STIMULATION AND SPERMINE AND SPERMIDINE CONTENT OF LACTIC ACID BACTERIA.
Topics: Amines; Anti-Bacterial Agents; Carrier Proteins; Culture Media; Escherichia coli; Lactic Acid; Lactobacillus; Polyamines; Putrescine; Research; Spermidine; Spermine | 1964 |
IDENTIFICATION OF THE AMINOALDEHYDES PRODUCED BY THE OXIDATION OF SPERMINE AND SPERMIDINE WITH PURIFIED PLASMA AMINE OXIDASE.
Topics: Aldehydes; Amines; Animals; Cattle; Chemistry Techniques, Analytical; Chromatography; Metabolism; Monoamine Oxidase; Oxidation-Reduction; Oxidoreductases; Research; Spectrophotometry; Spermidine; Spermine | 1964 |
SPERMIDINE AND SPERMINE IN RAT TISSUES AT DIFFERENT AGES.
Topics: Adipose Tissue; Aging; Amines; Animals; Animals, Newborn; Brain; Coloring Agents; Electrophoresis; Female; Humans; Intestine, Large; Intestines; Kidney; Liver; Lung; Male; Metabolism; Molecular Weight; Muscles; Myocardium; Rats; Research; Seminal Vesicles; Spermidine; Spermine; Spleen; Stomach; Testis; Thymus Gland; Uterus | 1964 |
ANALOGS OF SPERMINE AND SPERMIDINE. I. SYNTHESIS OF POLYMETHYLENEPOLYAMINES BY REDUCTION OF CYANOETHYLATED ALPHA,OMEGA-ALKYLENEDIAMINES.
Topics: Amines; Antineoplastic Agents; Chemistry, Pharmaceutical; Cyanides; Mice; Organic Chemicals; Pharmacology; Research; Spermidine; Spermine | 1964 |
SPERMINE AND SPERMIDINE IN BLOOD CELLS, AND A POSSIBLE OCCURRENCE OF SPERMINE IN CELL NUCLEUS.
Topics: Amines; Animals; Anura; Birds; Blood; Cats; Cell Nucleus; Erythrocytes; Fishes; Guinea Pigs; Leukemia; Leukocytes; Poultry; Rabbits; Spermidine; Spermine | 1965 |
Spermine and spermidine in normal human blood.
Topics: Humans; Spermidine; Spermine | 1962 |
Onset of DNA aggregation in presence of monovalent and multivalent counterions.
Topics: Adsorption; Binding Sites; Biogenic Polyamines; Complex Mixtures; Computer Simulation; Crystallization; DNA; Electrochemistry; Ions; Macromolecular Substances; Models, Chemical; Reproducibility of Results; Sensitivity and Specificity; Solutions; Spermidine; Spermine | 2003 |
Fos-B expression is required for polyamine-induced increase in nuclear activator protein-1 DNA binding in discrete structures of murine brain.
Topics: Animals; Bacterial Proteins; Brain; Caseins; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Histones; Immunohistochemistry; Male; Mice; Neurons; Phosphorylation; Proto-Oncogene Proteins c-fos; Putrescine; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Transcription Factor AP-1; Transcription, Genetic; Up-Regulation | 2003 |
Direct tris(2,2'-bipyridyl)ruthenium (II) electrochemiluminescence detection of polyamines separated by capillary electrophoresis.
Topics: 2,2'-Dipyridyl; Buffers; Cadaverine; Electrochemistry; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Luminescent Measurements; Organometallic Compounds; Polyamines; Putrescine; Reproducibility of Results; Ruthenium; Spermidine; Spermine; Time Factors | 2003 |
Inhibitory and promotive effects of polyamines on transglutaminase-induced protein polymerization.
Topics: Animals; Caseins; Cross-Linking Reagents; Dipeptides; Electrophoresis, Polyacrylamide Gel; Enzyme Activators; Enzyme Inhibitors; GTP-Binding Proteins; Guinea Pigs; Male; Polyamines; Polymers; Protein Glutamine gamma Glutamyltransferase 2; Putrescine; Spermidine; Spermine; Transglutaminases | 2003 |
Polyamine concentrations in the brain of vitamin B12-deficient rats.
Topics: Animals; Brain; Homocysteine; Liver; Male; Methionine; Neurons; Polyamines; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Kinetic evidence for the existence and mechanism of formation of a barrel stave structure from pore-forming dendrimers.
Topics: Cholic Acid; Glutathione; Kinetics; Lipid Bilayers; Liposomes; Lysine; Phosphatidylcholines; Polyamines; Sodium; Spermidine; Spermine; Structure-Activity Relationship | 2003 |
Spermidine but not spermine is essential for hypusine biosynthesis and growth in Saccharomyces cerevisiae: spermine is converted to spermidine in vivo by the FMS1-amine oxidase.
Topics: Base Sequence; DNA, Fungal; Eukaryotic Translation Initiation Factor 5A; Genes, Fungal; Kinetics; Lysine; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Polyamine Oxidase; RNA-Binding Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spermidine; Spermine; Substrate Specificity | 2003 |
Effect of diethylstilbestrol on polyamine metabolism in hamster epididymis.
Topics: Acetyltransferases; Animals; Cricetinae; Diethylstilbestrol; Epididymis; Male; Mesocricetus; Organ Size; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 2003 |
Two modes of polyamine block regulating the cardiac inward rectifier K+ current IK1 as revealed by a study of the Kir2.1 channel expressed in a human cell line.
Topics: Cell Line; Cytoplasm; Drug Synergism; Electric Conductivity; Homeostasis; Humans; Models, Biological; Myocardium; Potassium Channels, Inwardly Rectifying; Reaction Time; Spermidine; Spermine | 2004 |
[Relationship between floral differentiation and endogenous hormones and polyamines contents in cucumber cotyledonary nodes cultured in vitro].
Topics: Biogenic Polyamines; Cucumis sativus; Culture Techniques; Flowers; Gibberellins; Indoleacetic Acids; Plant Growth Regulators; Plant Shoots; Putrescine; Spermidine; Spermine; Zeatin | 2003 |
Polyamine levels in brain and plasma after acute restraint or water-immersion restraint stress in mice.
Topics: Animals; Anti-Anxiety Agents; Brain; Diazepam; Frontal Lobe; Hippocampus; Hypothalamus; Male; Mice; Mice, Inbred ICR; Polyamines; Putrescine; Restraint, Physical; Spermidine; Spermine; Stress, Psychological; Up-Regulation | 2004 |
Immunomodulatory action of spermine and spermidine on NR8383 macrophage line in various culture conditions.
Topics: Animals; Cell Culture Techniques; Cell Line; Chemokine CCL2; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Lipopolysaccharides; Macrophages, Alveolar; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spermidine; Spermine; Tumor Necrosis Factor-alpha | 2003 |
Calculating the etiology of systemic lupus erythematosus.
Topics: Animals; Autoimmunity; Humans; Lupus Erythematosus, Systemic; Models, Immunological; Polyamines; Putrescine; Spermidine; Spermine | 2004 |
Synthesis and antifungal activity of five classes of diamines.
Topics: Benzylamines; Diamines; Ethanolamines; Fungi; Fungicides, Industrial; Molecular Structure; Mycelium; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Pyridines; Spermidine; Spermine | 2004 |
Uptake of GABA and putrescine by UGA4 on the vacuolar membrane in Saccharomyces cerevisiae.
Topics: Azides; Biological Transport; Carrier Proteins; Cell Division; Enzyme Induction; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Intracellular Membranes; Macrolides; Nickel; Organic Anion Transporters; Ornithine Decarboxylase; Polyamines; Putrescine; Recombinant Proteins; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spermidine; Spermine; Subcellular Fractions; Vacuoles | 2004 |
Biogenic amines in restructured beef steaks as affected by added walnuts and cold storage.
Topics: Animals; Biogenic Amines; Cadaverine; Cattle; Cold Temperature; Dose-Response Relationship, Drug; Food Handling; Histamine; Juglans; Meat Products; Plant Extracts; Putrescine; Spermidine; Spermine; Time Factors; Transglutaminases | 2004 |
In vitro effects of polyamines on polymorphonuclear cell apoptosis and implications in the pathogenesis of periodontal disease.
Topics: Apoptosis; Caspase 3; Caspase 8; Caspases; Cell Nucleus; DNA; DNA Fragmentation; fas Receptor; Humans; Indoles; Microscopy, Fluorescence; Neutrophils; Periodontal Diseases; Polyamines; Putrescine; Spermidine; Spermine | 2004 |
Immunoelectron microscopy study of polyamines using a newly prepared monoclonal antibody against spermidine: use of a mixture of glutaraldehyde and paraformaldehyde as a cross-linking agent in the preparation of the antigen.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Borohydrides; Cross-Linking Reagents; Enzyme-Linked Immunosorbent Assay; Female; Formaldehyde; Glutaral; Haptens; Hybridomas; Immunoglobulin G; Immunohistochemistry; Intestinal Mucosa; Male; Mice; Mice, Inbred BALB C; Microscopy, Immunoelectron; Motor Neurons; Pancreas; Polyamines; Polymers; Rats; Rats, Wistar; Serum Albumin, Bovine; Spermidine; Spermine; Spinal Cord; Tissue Fixation; Vaccination | 2004 |
Characterization of arginine decarboxylase from Dianthus caryophyllus.
Topics: Calcium; Carboxy-Lyases; Dianthus; Enzyme Inhibitors; Kinetics; Magnesium; Metals, Heavy; Plant Proteins; Putrescine; Recombinant Fusion Proteins; Spermidine; Spermine | 2004 |
Polyamine metabolism in a member of the phylum Microspora (Encephalitozoon cuniculi): effects of polyamine analogues.
Topics: Acetyltransferases; Animals; Antiprotozoal Agents; Cell Line; Encephalitozoon cuniculi; Enzyme Inhibitors; Humans; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Rabbits; Spermidine; Spermine; Substrate Specificity | 2004 |
Polyamines reduces lipid peroxidation induced by different pro-oxidant agents.
Topics: Animals; Antioxidants; Biguanides; Biogenic Polyamines; Dizocilpine Maleate; Edetic Acid; Iron; Lipid Peroxidation; Nitroprusside; Oxidants; Quinolinic Acid; Rats; Rats, Wistar; Spermidine; Spermine; Thiobarbituric Acid Reactive Substances | 2004 |
[Establishment of an ELISA system of N1,N12-diacetylspermine in human urine].
Topics: Biomarkers, Tumor; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Humans; Reagent Kits, Diagnostic; Sensitivity and Specificity; Spermidine; Spermine | 2004 |
[Urine diacetylspermine as a novel tumor marker for pancreatobiliary carcinomas].
Topics: Adult; Aged; Aged, 80 and over; Biliary Tract Neoplasms; Biomarkers, Tumor; CA-19-9 Antigen; Carcinoembryonic Antigen; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Neoplasm Staging; Neoplasms; Pancreatic Neoplasms; Sensitivity and Specificity; Spermidine; Spermine | 2004 |
Modulation of the polyamine biosynthetic pathway in transgenic rice confers tolerance to drought stress.
Topics: Adaptation, Physiological; Desiccation; Disasters; Gene Expression Regulation, Plant; Genes, Plant; Models, Biological; Oryza; Phenotype; Plant Diseases; Plant Proteins; Plants, Genetically Modified; Polyamines; Putrescine; Spermidine; Spermine; Transgenes | 2004 |
Polyamine uptake in cultured cerebellar granule neurons.
Topics: Animals; Astrocytes; Biogenic Polyamines; Brain Neoplasms; Cell Line, Tumor; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Glutamic Acid; Kinetics; Membrane Potentials; Mice; Neuroblastoma; Neurons; Putrescine; Spermidine; Spermine; Synaptosomes | 2004 |
Maintained regulation of polyamines in spinal cord from patients with amyotrophic lateral sclerosis.
Topics: Aged; Amyotrophic Lateral Sclerosis; Animals; Biogenic Polyamines; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Postmortem Changes; Putrescine; Rats; Rats, Sprague-Dawley; Sex Factors; Spermidine; Spermine; Spinal Cord; Up-Regulation | 2004 |
Effect of NaCl and mannitol iso-osmotic stresses on proline and free polyamine levels in embryogenic Fraxinus angustifolia callus.
Topics: Climate; Disasters; Fraxinus; Kinetics; Mannitol; Osmolar Concentration; Polyamines; Proline; Putrescine; Seeds; Sodium Chloride; Spermidine; Spermine | 2004 |
Changes in polyamine concentration associated with aging in Pinus radiata and Prunus persica.
Topics: Biogenic Polyamines; Pinus; Prunus; Putrescine; Seedlings; Spermidine; Spermine; Trees | 2004 |
Interhelical spacing in liquid crystalline spermine and spermidine-DNA precipitates.
Topics: Animals; Cattle; Cholesterol; DNA; Dose-Response Relationship, Drug; Ions; Models, Chemical; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleosomes; Phosphates; Polyamines; RNA; Salts; Sodium Chloride; Spermidine; Spermine; Thymus Gland; Time Factors; X-Ray Diffraction | 2005 |
Role of polyamines in the function of nuclear transcription factor NF-kappaB in breast cancer cells.
Topics: Animals; Blotting, Western; Breast Neoplasms; Carcinoma 256, Walker; Cell Line, Tumor; Cell Nucleus; Eflornithine; Female; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Experimental; Mice; Neoplasm Proteins; Neoplasm Transplantation; NF-kappa B; NF-kappa B p50 Subunit; Polyamines; Putrescine; Rats; Spermidine; Spermine; Surface Plasmon Resonance; Transcription Factor RelA; Transcriptional Activation | 2004 |
Polyamine synthesis from proline in the developing porcine placenta.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amniotic Fluid; Animals; Arginase; Carbon Radioisotopes; Female; Fetal Development; Male; Methionine; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Placenta; Placentation; Polyamines; Pregnancy; Proline; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Sus scrofa | 2005 |
Effects of polyamines on human umbilical artery tone in vitro.
Topics: Adult; Female; Gestational Age; Humans; In Vitro Techniques; Polyamines; Pregnancy; Spermidine; Spermine; Umbilical Arteries; Vasodilation | 2004 |
Inhibition of in vitro pyrraline formation by L-arginine and polyamines.
Topics: Animals; Arginine; Cadaverine; Cattle; Dose-Response Relationship, Drug; Glucose; Glycation End Products, Advanced; Norleucine; Polyamines; Putrescine; Pyrroles; Serum Albumin, Bovine; Spermidine; Spermine | 2004 |
Characteristics of the polyamine transporter TPO1 and regulation of its activity and cellular localization by phosphorylation.
Topics: Amino Acid Sequence; Antiporters; Biological Transport; Cell Membrane; Endoplasmic Reticulum; Genotype; Kinetics; Membrane Transport Proteins; Molecular Sequence Data; Organic Cation Transport Proteins; Phosphorylation; Polyamines; Protein Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spermidine; Spermine | 2005 |
Contribution of hydrophobicity to thermodynamics of ligand-DNA binding and DNA collapse.
Topics: Binding Sites; DNA; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Nucleic Acid Conformation; Nucleic Acid Denaturation; Particle Size; Spermidine; Spermine; Thermodynamics | 2005 |
Polyamines inhibit apoptosis in porcine parthenotes developing in vitro.
Topics: Animals; Apoptosis; Blastocyst; In Vitro Techniques; Parthenogenesis; Polyamines; Putrescine; Spermidine; Spermine; Swine | 2005 |
Involvement of polyamines in evening primrose extract-induced apoptosis in Ehrlich ascites tumor cells.
Topics: Animals; Apoptosis; Carcinoma, Ehrlich Tumor; Cell Survival; Chromatography, High Pressure Liquid; DNA, Neoplasm; Dose-Response Relationship, Drug; Oenothera biennis; Plant Extracts; Polyamines; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 2005 |
Uptake of putrescine and spermidine by Gap1p on the plasma membrane in Saccharomyces cerevisiae.
Topics: Amino Acid Transport Systems; Cell Membrane; Dose-Response Relationship, Drug; Membrane Proteins; Metabolic Clearance Rate; Putrescine; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spermidine; Spermine | 2005 |
Supramolecular modulation of action of polyamine on enzyme/DNA interactions.
Topics: Biogenic Polyamines; Bridged-Ring Compounds; DNA; Enzymes; Imidazoles; Molecular Structure; Spermidine; Spermine | 2005 |
Control of spermidine and spermine levels in rat tissues by trans-4-methylcyclohexylamine, a spermidine-synthase inhibitor.
Topics: Alkenes; Animals; Cyclohexylamines; Dose-Response Relationship, Drug; Down-Regulation; Drug Administration Schedule; Gene Expression Regulation; Male; Rats; Spermidine; Spermidine Synthase; Spermine; Up-Regulation; Weight Loss | 2005 |
Vesicle formed by amphiphilc cucurbit[6]uril: versatile, noncovalent modification of the vesicle surface, and multivalent binding of sugar-decorated vesicles to lectin.
Topics: Bridged-Ring Compounds; Concanavalin A; Drug Delivery Systems; Fluorescein-5-isothiocyanate; Imidazoles; Kinetics; Mannose; Spermidine; Spermine; Surface Plasmon Resonance; Surface Properties | 2005 |
Antioxidative properties of natural polyamines and dimethylsilane analogues.
Topics: Antioxidants; Erythrocytes; Free Radical Scavengers; Humans; Hydroxyl Radical; Methenamine; Polyamines; Reference Values; Silanes; Spermidine; Spermine; Structure-Activity Relationship | 2005 |
Acute pancreatitis induced by activation of the polyamine catabolism in gene-modified mice and rats overexpressing spermidine/spermine N1-acetyltransferase.
Topics: Acute Disease; Animals; Biomarkers; Disease Models, Animal; Mice; Mice, Transgenic; Pancreatitis; Rats; Rats, Inbred Strains; Sensitivity and Specificity; Spermidine; Spermine | 2005 |
Depletion of polyamines and increase of transforming growth factor-beta1, c-myc, collagen-type I, matrix metalloproteinase-1, and metalloproteinase-2 mRNA in primary human gingival fibroblasts.
Topics: Adult; Cell Count; Cell Proliferation; Cells, Cultured; Collagen Type I; Eflornithine; Enzyme Inhibitors; Extracellular Matrix; Female; Fibroblasts; Gingiva; Humans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Proto-Oncogene Proteins c-myc; Putrescine; RNA, Messenger; Spermidine; Spermine; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta | 2005 |
Differential effects of polyamine derivative compounds against Leishmania infantum promastigotes and axenic amastigotes.
Topics: Animals; Antiparasitic Agents; Apoptosis; Biogenic Polyamines; DNA Fragmentation; DNA, Protozoan; Flow Cytometry; Fluorescent Antibody Technique; In Situ Nick-End Labeling; Leishmania infantum; Membrane Potentials; Mitochondria; Permeability; Phosphatidylserines; Putrescine; Quinolones; Spermidine; Spermine | 2005 |
The spermidine synthase of the malaria parasite Plasmodium falciparum: molecular and biochemical characterisation of the polyamine synthesis enzyme.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Erythrocytes; Escherichia coli; Humans; Kinetics; Molecular Sequence Data; Plasmodium falciparum; Spermidine; Spermidine Synthase; Spermine | 2005 |
Polyamine-vectored iron chelators: the role of charge.
Topics: Animals; Carrier Proteins; Cell Line, Tumor; Drug Delivery Systems; Electricity; Esters; Iron Chelating Agents; Male; Mice; Polyamines; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Structure-Activity Relationship; Thiazoles | 2005 |
Dihydrocaffeoyl polyamines (kukoamine and allies) in potato (Solanum tuberosum) tubers detected during metabolite profiling.
Topics: Plant Tubers; Polyamines; Solanum tuberosum; Spermidine; Spermine | 2005 |
Spermine, a natural polyamine, suppresses LFA-1 expression on human lymphocyte.
Topics: CD11a Antigen; CD18 Antigens; Cell Adhesion; Endothelium, Vascular; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Lymphocyte Activation; Lymphocyte Function-Associated Antigen-1; Lymphocyte Subsets; Lymphocytes; Putrescine; Spermidine; Spermine | 2005 |
Incomplete ion dissociation underlies the weakened attraction between DNA helices at high spermidine concentrations.
Topics: Animals; Anions; Chickens; Chlorides; Cobalt; DNA; Ions; Kinetics; Methenamine; Nucleic Acid Conformation; Osmosis; Osmotic Pressure; Pressure; Protein Binding; Salts; Scattering, Radiation; Sodium; Spermidine; Spermine; Static Electricity; Thermodynamics; X-Rays | 2005 |
Overexpression of ADC2 in Arabidopsis induces dwarfism and late-flowering through GA deficiency.
Topics: Arabidopsis; Arabidopsis Proteins; Carboxy-Lyases; Flowers; Gene Expression Regulation, Plant; Gibberellins; Phenotype; Plants, Genetically Modified; Protein Array Analysis; Putrescine; Spermidine; Spermine | 2005 |
Endogenous free polyamines and their role in fruit set of low and high parthenocarpic ability citrus cultivars.
Topics: Citrus; Flowers; Fruit; Plant Leaves; Putrescine; Seeds; Species Specificity; Spermidine; Spermine | 2005 |
Boron deficiency increases putrescine levels in tobacco plants.
Topics: Boron; Nicotiana; Plant Leaves; Plant Roots; Plant Shoots; Putrescine; Spermidine; Spermine; Time Factors | 2005 |
Induction of apoptosis by spermine-metabolites in primary human blood cells and various tumor cell lines.
Topics: Acetylcysteine; Amine Oxidase (Copper-Containing); Amino Acid Chloromethyl Ketones; Apoptosis; Apoptosis Regulatory Proteins; Caspase Inhibitors; Cell Line, Tumor; Cytochromes c; Dexamethasone; fas Receptor; Humans; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Leukocytes, Mononuclear; Lymphoproliferative Disorders; Membrane Potentials; Mitochondria; Mitochondrial Proteins; Polyamines; Proto-Oncogene Proteins c-bcl-2; Putrescine; Reactive Oxygen Species; Spermidine; Spermine | 2005 |
Overproduction of cardiac S-adenosylmethionine decarboxylase in transgenic mice.
Topics: Adenosylmethionine Decarboxylase; Animals; Female; Gene Expression Regulation, Enzymologic; Heart; Isoproterenol; Male; Mice; Mice, Transgenic; Myocardium; Organ Size; Ornithine Decarboxylase; Phenotype; Putrescine; Spermidine; Spermine | 2006 |
Influence of cultivar and germination on bioactive amines in soybeans (Glycine max L. Merril).
Topics: Agmatine; Biogenic Amines; Cadaverine; Germination; Glycine max; Putrescine; Seeds; Species Specificity; Spermidine; Spermine | 2005 |
Polyamines promote root elongation and growth by increasing root cell division in regenerated Virginia pine (Pinus virginiana Mill.) plantlets.
Topics: Amine Oxidase (Copper-Containing); Biogenic Polyamines; Cells, Cultured; Dose-Response Relationship, Drug; Mitosis; Mitotic Index; Oxidoreductases Acting on CH-NH Group Donors; Pinus; Plant Roots; Polyamine Oxidase; Putrescine; Regeneration; Spermidine; Spermine; Survival Rate; Up-Regulation | 2005 |
Immunoelectron microscopic study of polyamines in the gastrointestinal tract of rat.
Topics: Animals; Cell Nucleus; Duodenum; Endoplasmic Reticulum, Rough; Gastric Mucosa; Intestine, Small; Male; Microscopy, Immunoelectron; Mitochondria; Rats; Rats, Wistar; Ribosomes; Secretory Vesicles; Spermidine; Spermine | 2006 |
Polyamine stress at high pH in Escherichia coli K-12.
Topics: Electrophoresis, Gel, Two-Dimensional; Escherichia coli K12; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Polyamines; Spermidine; Spermine | 2005 |
Transport of polyamines in Drosophila S2 cells: kinetics, pharmacology and dependence on the plasma membrane proton gradient.
Topics: Animals; Biological Transport; Calcium; Carrier Proteins; Cell Line; Cell Membrane; Chlorides; Drosophila melanogaster; Hydrogen-Ion Concentration; Kinetics; Mitoguazone; Paraquat; Potassium; Proton-Motive Force; Sodium; Spermidine; Spermine | 2006 |
Characterization of putrescine uptake in hamster amelanocytic melanoma AMEL-3 cells.
Topics: Amidines; Animals; Biological Transport; Cell Cycle; Cricetinae; Dose-Response Relationship, Drug; Down-Regulation; Ethylmaleimide; Hydrogen-Ion Concentration; Kinetics; Melanoma, Amelanotic; Mesocricetus; Putrescine; Skin Neoplasms; Spermidine; Spermine; Sulfhydryl Reagents; Time Factors; Tumor Cells, Cultured | 2005 |
Polyamine conjugates of meso-tritolylporphyrin and protoporphyrin IX: potential agents for photodynamic therapy of cancers.
Topics: Antineoplastic Agents; Dihematoporphyrin Ether; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Necrosis; Photochemotherapy; Polyamines; Porphyrins; Protoporphyrins; Spectroscopy, Fourier Transform Infrared; Spermidine; Spermine; Time Factors; Tumor Cells, Cultured | 2006 |
Correlation of ovary and leaf spermidine and spermine content with the alternate bearing habit of olive.
Topics: Calcium; Chromatography, High Pressure Liquid; Olea; Plant Leaves; Potassium; Spermidine; Spermine | 2005 |
Alteration of Rb binding to HPV 18 E7 modified by transglutaminase 2 with different type of polyamines.
Topics: Amines; Biotinylation; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; E2F Transcription Factors; Gene Expression Regulation, Enzymologic; Genes, Regulator; Genes, Retinoblastoma; Glutathione Transferase; GTP-Binding Proteins; Humans; Immunohistochemistry; Models, Chemical; Oncogene Proteins, Viral; Polyamines; Protein Binding; Protein Glutamine gamma Glutamyltransferase 2; Recombinant Proteins; Retinoblastoma Protein; Spermidine; Spermine; Transcriptional Activation; Transfection; Transglutaminases | 2006 |
Alpha-methyl polyamines: efficient synthesis and tolerance studies in vivo and in vitro. First evidence for dormant stereospecificity of polyamine oxidase.
Topics: Animals; Animals, Genetically Modified; Dose-Response Relationship, Drug; Drug Tolerance; Fibroblasts; Humans; In Vitro Techniques; Kidney; Liver; Mice; Molecular Structure; Oxidoreductases Acting on CH-NH Group Donors; Pancreas; Polyamine Oxidase; Rats; Recombinant Proteins; Spermidine; Spermine; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 2006 |
Novel oral formulation safely improving intestinal absorption of poorly absorbable drugs: utilization of polyamines and bile acids.
Topics: Adjuvants, Pharmaceutic; Administration, Oral; Alanine; Animals; Anti-Ulcer Agents; Area Under Curve; Biological Availability; Colon; Gastric Mucosa; Intestinal Absorption; Male; Quinolones; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Taurocholic Acid | 2006 |
Host macrophages produce diacetylspermine related with tumorigenesis.
Topics: Animals; Cell Line, Tumor; Coculture Techniques; Dose-Response Relationship, Drug; Female; Glucose; Humans; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Putrescine; Spermidine; Spermine; Spleen; Thioglycolates | 2006 |
Shoot-applied polyamines suppress nodule formation in soybean (Glycine max).
Topics: Brassinosteroids; Cholestanols; Down-Regulation; Glycine max; Perchlorates; Plant Growth Regulators; Plant Roots; Plant Shoots; Plant Stems; Polyamines; Putrescine; Spermidine; Spermine; Steroids, Heterocyclic | 2006 |
Role of polyamines in peach fruit development and storage.
Topics: Adenosylmethionine Decarboxylase; Carboxy-Lyases; Ethylenes; Fruit; Ornithine Decarboxylase; Polyamines; Prunus; Putrescine; Spermidine; Spermidine Synthase; Spermine; Spermine Synthase | 2006 |
Expression, crystallization and preliminary X-ray crystallographic analysis of human agmatinase.
Topics: Agmatine; Arginine; Carboxy-Lyases; Catalysis; Crystallography, X-Ray; Diamines; DNA, Complementary; Escherichia coli; Humans; Hydrolysis; Kidney; Magnesium; Mitochondria; Polyethylene Glycols; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Spermidine; Spermine; Temperature; Urea; Ureohydrolases; X-Ray Diffraction | 2005 |
Methylthioadenosine and polyamine biosynthesis in a Saccharomyces cerevisiae meu1delta mutant.
Topics: Adenosine; Gene Deletion; Methionine; Mutation; Purine-Nucleoside Phosphorylase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spermidine; Spermine; Thionucleosides | 2006 |
Regulatory role of polyamine in the acid phosphatase from potato tubers.
Topics: Acid Phosphatase; Calcium; Diphosphates; Kinetics; Magnesium; Polyamines; Solanum tuberosum; Spermidine; Spermine | 2006 |
Polyamines as a defense mechanism against lipoperoxidation in Trypanosoma cruzi.
Topics: Animals; Cadaverine; Cell Membrane; Dose-Response Relationship, Drug; Hydrogen Peroxide; Lipid Peroxidation; Nifurtimox; Putrescine; Reactive Oxygen Species; Spermidine; Spermine; Superoxide Dismutase; Time Factors; Trypanosoma cruzi | 2006 |
Effects of glucocorticoids on polyamine metabolism in liver and spleen of guinea pig during sensitization.
Topics: Animals; Cytokines; Dexamethasone; Freund's Adjuvant; Glucocorticoids; Guinea Pigs; Immunization; Liver; Male; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Serum Albumin, Bovine; Spermidine; Spermine; Spleen | 2006 |
Enhancement of transglutaminase activity and polyamine depletion in B16-F10 melanoma cells by flavonoids naringenin and hesperitin correlate to reduction of the in vivo metastatic potential.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Enzyme Activation; Estrogen Antagonists; Flavanones; Melanoma; Mice; Neoplasm Metastasis; Neoplasm Proteins; Spermidine; Spermine; Transglutaminases | 2007 |
Effects of polyamines on two strains of Trypanosoma brucei in infected rats and in vitro culture.
Topics: Amide Synthases; Animals; Culture Media; Eflornithine; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutathione; Hematocrit; Hydrogen Peroxide; Male; NADH, NADPH Oxidoreductases; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxidative Stress; Polyamines; Putrescine; Rats; Rats, Wistar; RNA, Messenger; Spermidine; Spermine; Trypanosoma brucei brucei; Trypanosomiasis, African | 2006 |
Polyamine metabolism in sunflower plants under long-term cadmium or copper stress.
Topics: Amine Oxidase (Copper-Containing); Cadmium; Carboxy-Lyases; Chlorophyll; Copper; Helianthus; Metals; Ornithine Decarboxylase; Polyamines; Proline; Putrescine; Spermidine; Spermine; Time Factors; Water | 2007 |
Bending of the estrogen response element by polyamines and estrogen receptors alpha and beta: a fluorescence resonance energy transfer study.
Topics: Allosteric Regulation; DNA; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Fluorescence Resonance Energy Transfer; Kinetics; Nucleic Acid Conformation; Oligonucleotides; Polyamines; Putrescine; Recombinant Proteins; Response Elements; Spermidine; Spermine; Structure-Activity Relationship | 2006 |
Heterologous expression and biochemical characterization of a polyamine oxidase from Arabidopsis involved in polyamine back conversion.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Base Sequence; Cloning, Molecular; DNA, Complementary; Escherichia coli; Hydrogen-Ion Concentration; Molecular Sequence Data; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Recombinant Fusion Proteins; Sequence Alignment; Spermidine; Spermine | 2006 |
Polyamine-regulated unproductive splicing and translation of spermidine/spermine N1-acetyltransferase.
Topics: Acetyltransferases; Alternative Splicing; Animals; Exons; Female; Gene Expression Regulation, Enzymologic; Mice; Mice, Transgenic; Pregnancy; Protein Biosynthesis; Protein Synthesis Inhibitors; RNA Precursors; RNA, Messenger; RNA, Small Interfering; Spermidine; Spermine | 2006 |
Ring of negative charge in BK channels facilitates block by intracellular Mg2+ and polyamines through electrostatics.
Topics: Algorithms; Animals; Female; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Large-Conductance Calcium-Activated Potassium Channels; Magnesium; Membrane Potentials; Mice; Models, Biological; Mutation; Oocytes; Patch-Clamp Techniques; Polyamines; Potassium; Potassium Channels, Inwardly Rectifying; Putrescine; RNA, Complementary; Spermidine; Spermine; Static Electricity; Xenopus laevis | 2006 |
Polyamine deficiency leads to accumulation of reactive oxygen species in a spe2Delta mutant of Saccharomyces cerevisiae.
Topics: Apoptosis; Fluoresceins; Fluorescent Dyes; Microscopy, Confocal; Microscopy, Fluorescence; Mutation; Reactive Oxygen Species; Rhodamines; Saccharomyces cerevisiae; Spermidine; Spermine; Superoxide Dismutase | 2006 |
Changes of free, soluble conjugated and bound polyamine titers of jojoba explants under sodium chloride salinity in vitro.
Topics: Adaptation, Physiological; Magnoliopsida; Putrescine; Sodium Chloride; Solubility; Spermidine; Spermine | 2007 |
Polyamines, PI(4,5)P2, and actin polymerization.
Topics: Actins; Animals; Cells, Cultured; Cytoskeleton; Eflornithine; HL-60 Cells; Humans; PC12 Cells; Phosphatidylinositol 4,5-Diphosphate; Polyamines; Putrescine; Rats; Spermidine; Spermine; Substrate Specificity; Time Factors | 2006 |
Polyamine synthesis and salvage pathways in the malaria parasite Plasmodium falciparum.
Topics: Animals; Biological Transport; Erythrocytes; Humans; Jurkat Cells; Plasmodium falciparum; Polyamines; Putrescine; Spermidine; Spermine | 2006 |
Concentrations of putrescine, spermidine, and spermine in duodenum and pancreas as affected by the ratio of arginine to lysine and source of methionine in broilers under heat stress.
Topics: Age Factors; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Dose-Response Relationship, Drug; Duodenum; Heat Stress Disorders; Hot Temperature; Lysine; Male; Methionine; Nutritional Requirements; Pancreas; Poultry Diseases; Putrescine; Random Allocation; Spermidine; Spermine; Weight Gain | 2006 |
Changes in free polyamine titers and expression of polyamine biosynthetic genes during growth of peach in vitro callus.
Topics: Arginine; Cell Culture Techniques; Gene Expression Regulation, Plant; Genes, Plant; Polyamines; Prunus; Putrescine; Spermidine; Spermine | 2007 |
[Content comparison of polyamines compounds in Penis et Testis Cervi].
Topics: Animals; Chromatography, High Pressure Liquid; Deer; Male; Materia Medica; Penis; Polyamines; Putrescine; Quality Control; Spermidine; Spermine; Testis | 2006 |
Increased blood spermine levels decrease the cytotoxic activity of lymphokine-activated killer cells: a novel mechanism of cancer evasion.
Topics: Cell Adhesion; Humans; Killer Cells, Lymphokine-Activated; Lymphocyte Subsets; Neoplasms; Spermidine; Spermine; Tumor Escape | 2007 |
Liver I/R injury is improved by the arginase inhibitor, N(omega)-hydroxy-nor-L-arginine (nor-NOHA).
Topics: Alanine Transaminase; Animals; Arginase; Arginine; Aspartate Aminotransferases; Biogenic Polyamines; Liver; Liver Transplantation; Male; Nitrates; Nitric Oxide; Nitrites; Ornithine; Putrescine; Rats; Rats, Inbred Lew; Reperfusion Injury; Spermidine; Spermine | 2007 |
Nuclear magnetic resonance spectroscopy-based metabolite profiling of transgenic tomato fruit engineered to accumulate spermidine and spermine reveals enhanced anabolic and nitrogen-carbon interactions.
Topics: Amino Acids; Carbohydrate Metabolism; Carbon; Choline; Fruit; Gene Expression Regulation, Plant; Isocitrate Dehydrogenase; Nitrogen; Nuclear Magnetic Resonance, Biomolecular; Phosphoenolpyruvate Carboxylase; Plants, Genetically Modified; RNA, Messenger; Signal Transduction; Solanum lycopersicum; Spermidine; Spermine | 2006 |
Polyamine-induced bundling of F-actin.
Topics: Actin Cytoskeleton; Actins; Magnesium; Polyamines; Protein Binding; Spermidine; Spermine | 2006 |
Differential regulation of ionotropic glutamate receptors.
Topics: Binding Sites; Ligands; Models, Molecular; Pregnanolone; Pregnenolone; Protein Structure, Tertiary; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Zinc | 2007 |
Decrease of polyamine levels and enhancement of transglutaminase activity in selective reduction of B16-F10 melanoma cell proliferation induced by atrial natriuretic peptide.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Cell Line, Tumor; Cell Proliferation; Epidermal Growth Factor; Humans; Male; Melanins; Melanoma, Experimental; Muscle, Smooth, Vascular; Natriuretic Agents; Natriuretic Peptide, C-Type; Polyamines; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Transglutaminases | 2006 |
Transverse acoustic modes of biogenic and alpha,omega-polyamines: a study by inelastic neutron scattering and Raman spectroscopies coupled to DFT calculations.
Topics: Algorithms; Biogenic Polyamines; Molecular Structure; Neutron Diffraction; Polyamines; Quantum Theory; Spectrum Analysis, Raman; Spermidine; Spermine | 2006 |
Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Collagen; Drug Combinations; Eflornithine; Ki-67 Antigen; Laminin; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplasm Transplantation; Polyamines; Proteoglycans; Putrescine; Spermidine; Spermine | 2007 |
Effect of delta sleep-inducing peptide on macromolecule biosynthesis in brain tissue of stressed rodents.
Topics: Animals; Brain; Burns; Cerebral Cortex; Delta Sleep-Inducing Peptide; Macromolecular Substances; Male; Mice; Rats; Spermidine; Spermine; Stress, Psychological; Time Factors | 2006 |
Differential effects of paraquat on oxidative stress parameters and polyamine levels in two freshwater invertebrates.
Topics: Animals; Biomphalaria; Catalase; Fresh Water; Herbicides; Lipid Peroxidation; Oligochaeta; Oxidative Stress; Paraquat; Polyamines; Putrescine; Spermidine; Spermine; Superoxide Dismutase; Time Factors | 2007 |
Saponins from Tribulus terrestris L are less toxic for normal human fibroblasts than for many cancer lines: influence on apoptosis and proliferation.
Topics: Actins; Apoptosis; Caspase 3; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dual Specificity Phosphatase 1; Fibroblasts; Humans; Immediate-Early Proteins; Immunoblotting; Inhibitory Concentration 50; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Proteins; Putrescine; Saponins; Signal Transduction; Spermidine; Spermine; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Tribulus; Tritium | 2007 |
Biological polyamines inhibit nucleic-acid-induced polymerisation of prion protein.
Topics: Anilino Naphthalenesulfonates; Biogenic Polyamines; Biopolymers; Circular Dichroism; DNA; Fluorescent Dyes; Prions; Protein Folding; Protein Structure, Secondary; RNA, Transfer; Spermidine; Spermine; Temperature | 2007 |
The impact of Cu treatment on phenolic and polyamine levels in plant material regenerated from embryos obtained in anther culture of carrot.
Topics: Cadaverine; Cells, Cultured; Copper Sulfate; Daucus carota; Kinetics; Phenols; Polyamines; Putrescine; Spermidine; Spermine | 2007 |
Polyamine-based analogues as biochemical probes and potential therapeutics.
Topics: Animals; Antineoplastic Agents; Humans; Polyamines; Putrescine; Spermidine; Spermine; Structure-Activity Relationship; Trypanocidal Agents; Yersinia pestis | 2007 |
Novel approach to design an isosteric charge-deficient analogue of spermine and its biochemically important derivatives.
Topics: Amines; Chelating Agents; Drug Design; Hydrogen-Ion Concentration; Models, Molecular; Spermidine; Spermine | 2007 |
Vibrational spectroscopy studies on linear polyamines.
Topics: Chelating Agents; Models, Molecular; Neutrons; Polyamines; Putrescine; Scattering, Radiation; Spectrum Analysis, Raman; Spermidine; Spermine; Vibration | 2007 |
Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide.
Topics: Animals; Apoptosis; Cells, Cultured; DNA Damage; Eflornithine; Glutathione; Guanidines; Hydrogen Peroxide; In Situ Nick-End Labeling; Mice; Oxidative Stress; Reactive Oxygen Species; Spermidine; Spermine | 2007 |
Spermidine and spermine catalyze the formation of nanostructured titanium oxide.
Topics: Catalysis; Hydrogen-Ion Concentration; Kinetics; Microscopy, Electron, Scanning; Nanostructures; Particle Size; Spermidine; Spermine; Temperature; Titanium; X-Ray Diffraction | 2007 |
Dietary putrescine reduces the intestinal anticarcinogenic activity of sulindac in a murine model of familial adenomatous polyposis.
Topics: Adenomatous Polyposis Coli; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Cyclooxygenase Inhibitors; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Random Allocation; RNA, Messenger; Spermidine; Spermine; Sulindac | 2006 |
Polyamines upregulate the mRNA expression of cationic amino acid transporter-1 in human retinal pigment epithelial cells.
Topics: Animals; Cationic Amino Acid Transporter 1; Cell Line; Dose-Response Relationship, Drug; Eflornithine; Enzyme Inhibitors; Epithelial Cells; Humans; Large Neutral Amino Acid-Transporter 1; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Ornithine-Oxo-Acid Transaminase; Pigment Epithelium of Eye; Proto-Oncogene Proteins c-myc; Putrescine; RNA Interference; RNA, Messenger; RNA, Small Interfering; Spermidine; Spermine; Swine; Telomerase; Time Factors; Transfection; Up-Regulation | 2007 |
Spermine and spermidine inhibition of photosystem II: Disassembly of the oxygen evolving complex and consequent perturbation in electron donation from TyrZ to P680+ and the quinone acceptors QA- to QB.
Topics: Chlorophyll; Electron Transport; Electrons; Fluorescence; Manganese; Oxidation-Reduction; Oxygen; Peptides; Photosystem II Protein Complex; Quinones; Spermidine; Spermine | 2007 |
Development of a polyamine database for assessing dietary intake.
Topics: Beverages; Databases, Factual; Food Analysis; Fruit; Humans; Meat; Neoplasms; Pisum sativum; Polyamines; Putrescine; Spermidine; Spermine; Zea mays | 2007 |
Polyamines in tea processing.
Topics: Antioxidants; Camellia sinensis; Food Handling; Free Radical Scavengers; Glutathione Peroxidase; Lipid Peroxidation; Plant Leaves; Polyamines; Putrescine; Spermidine; Spermine; Superoxide Dismutase; Tea | 2007 |
The polyamines spermidine and spermine retard the platination rate of single-stranded DNA oligomers and plasmids.
Topics: Cations, Monovalent; DNA Adducts; DNA, Single-Stranded; Dose-Response Relationship, Drug; Kinetics; Oligonucleotides; Plasmids; Platinum Compounds; Sodium; Spermidine; Spermine | 2007 |
Improvement of pulmonary absorption of insulin and other water-soluble compounds by polyamines in rats.
Topics: Absorption; Animals; Blood Glucose; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Drug Interactions; Drug Stability; Fluorescein; Fluoresceins; Insulin; Lung; Male; Membranes; Polyamines; Putrescine; Rats; Rats, Wistar; Solubility; Spermidine; Spermine; Water | 2007 |
Exogenous spermidine differentially alters activities of some scavenging system enzymes, H(2)O(2) and superoxide radical levels in water-stressed cucumber leaves.
Topics: Catalase; Cucumis sativus; Dehydration; Free Radical Scavengers; Glutathione Peroxidase; Hydrogen Peroxide; Plant Leaves; Spermidine; Spermine; Superoxide Dismutase; Superoxides; Water | 2008 |
Polyamine homeostasis in arginase knockout mice.
Topics: Acetyltransferases; Amine Oxidase (Copper-Containing); Animals; Arginase; Biogenic Polyamines; Brain; Gene Expression; Homeostasis; Intestine, Small; Kidney; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Proteins; Putrescine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spermidine; Spermine | 2007 |
Electrostatic interaction of internal Mg2+ with membrane PIP2 Seen with KCNQ K+ channels.
Topics: Animals; Binding, Competitive; Cell Line; Cell Membrane; Dose-Response Relationship, Drug; Humans; Ion Channel Gating; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Magnesium; Membrane Potentials; Mice; Minor Histocompatibility Antigens; Models, Biological; Neomycin; Phosphatidylinositol 4,5-Diphosphate; Phosphotransferases (Alcohol Group Acceptor); Polyamines; Polylysine; Potassium; Potassium Channel Blockers; Putrescine; Rats; Spermidine; Spermine; Static Electricity; Tetraethylammonium; Time Factors; Transfection | 2007 |
Effects of spermine on the relaxation response of rat detrusor smooth muscles.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Bethanechol; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Potassium Chloride; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Tetraethylammonium; Urinary Bladder | 2007 |
Electrospray ionization and time-of-flight mass spectrometric method for simultaneous determination of spermidine and spermine.
Topics: Cell Line; Cells; Chromatography, High Pressure Liquid; Cyclohexylamines; Enzyme Inhibitors; Humans; Mass Spectrometry; Proteins; Reference Standards; Spectrometry, Mass, Electrospray Ionization; Spermidine; Spermine | 2007 |
Effects of polyamines on the functionality of photosynthetic membrane in vivo and in vitro.
Topics: Adenosine Triphosphate; Cell Fractionation; Chloroplasts; Nicotiana; Photosynthesis; Polyamines; Putrescine; Spermidine; Spermine; Thylakoids | 2007 |
Interplay of ion binding and attraction in DNA condensed by multivalent cations.
Topics: Animals; Binding, Competitive; Cations, Divalent; Cobalt; DNA; Models, Chemical; Nucleic Acid Conformation; Sodium; Spermidine; Spermine | 2008 |
Effects of Microdesmis keayana roots on sexual behavior of male rats.
Topics: Animals; Aphrodisiacs; Coumaric Acids; Female; Magnoliopsida; Male; Molecular Structure; Plant Extracts; Rats; Rats, Wistar; Sexual Behavior, Animal; Spermidine; Spermine | 2008 |
Participation of hippocampal ionotropic glutamate receptors in histamine H(1) antagonist-induced memory deficit in rats.
Topics: Animals; Concanavalin A; Cycloserine; Dioxoles; Dose-Response Relationship, Drug; Electroencephalography; Fourier Analysis; GluK2 Kainate Receptor; Hippocampus; Histamine H1 Antagonists; Injections; Male; Maze Learning; Mental Recall; Orientation; Piperidines; Pyrilamine; Pyrrolidinones; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Histamine H1; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Signal Processing, Computer-Assisted; Spermidine; Spermine; Theta Rhythm | 2008 |
Novel CoA-polyamine conjugates for effective inhibition of spermine/spermidine-N1-acetyltransferase.
Topics: Acetyltransferases; Antineoplastic Agents; Coenzyme A; Enzyme Inhibitors; Humans; Molecular Mimicry; Spermidine; Spermine; Structure-Activity Relationship | 2007 |
Glucose transport in fibroblasts is unaffected by polyamines.
Topics: Animals; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; Fibroblasts; Glucose; Polyamines; Putrescine; Spermidine; Spermine; Time Factors; Wound Healing | 2008 |
Polyamine metabolism in rat myocardial ischemia-reperfusion injury.
Topics: Acetyltransferases; Animals; Coronary Vessels; Disease Models, Animal; Heart Rate; Myocardial Reperfusion Injury; Myocardium; Ornithine Decarboxylase; Putrescine; Rats; Spermidine; Spermine | 2009 |
Biological activity of antitumoural MGBG: the structural variable.
Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Binding Sites; Calcium; Cell Membrane Permeability; Computer Simulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepatocytes; Hydrogen-Ion Concentration; Male; Mitochondria, Liver; Mitoguazone; Models, Biological; Models, Molecular; Quantum Theory; Rats; Rats, Wistar; Spermidine; Spermine; Structure-Activity Relationship; Time Factors | 2008 |
Transcriptome analysis of agmatine and putrescine catabolism in Pseudomonas aeruginosa PAO1.
Topics: Agmatine; Alanine Racemase; Alanine Transaminase; Aminohydrolases; Bacterial Proteins; gamma-Aminobutyric Acid; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genotype; Mass Spectrometry; Models, Biological; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Pseudomonas aeruginosa; Putrescine; Spermidine; Spermine | 2008 |
The possible roles for polyamines in the initiation process of SV40 DNA replication in vitro.
Topics: DNA Cleavage; DNA Polymerase I; DNA Primase; DNA Replication; DNA, Single-Stranded; Humans; Polyamines; Replication Protein A; Simian virus 40; Spermidine; Spermine; Topoisomerase I Inhibitors | 2008 |
Improvement of intestinal absorption of water-soluble macromolecules by various polyamines: intestinal mucosal toxicity and absorption-enhancing mechanism of spermine.
Topics: Animals; Dextrans; Diffusion; Dose-Response Relationship, Drug; Electric Impedance; Fluorescein-5-isothiocyanate; Intestinal Absorption; Intestinal Mucosa; Jejunum; L-Lactate Dehydrogenase; Male; Molecular Weight; Polyamines; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine | 2008 |
Ion binding in the open HCN pacemaker channel pore: fast mechanisms to shape "slow" channels.
Topics: Animals; Electric Conductivity; Electrophysiology; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Ions; Magnesium; Oocytes; Potassium; Protein Binding; Sodium; Spermidine; Spermine; Xenopus | 2008 |
Regulation by the exogenous polyamine spermidine of Na,K-ATPase activity from the gills of the euryhaline swimming crab Callinectes danae (Brachyura, Portunidae).
Topics: Adenosine Triphosphate; Animals; Brachyura; Fresh Water; Gills; Hydrolysis; Kinetics; Oceans and Seas; Potassium; Quaternary Ammonium Compounds; Sodium; Sodium-Potassium-Exchanging ATPase; Spermidine; Spermine | 2008 |
Measurement of spermidine/spermine-N1-acetyltransferase activity by high-performance liquid chromatography with N1-dansylnorspermine as the substrate.
Topics: Acetyl Coenzyme A; Acetyltransferases; Animals; Cell Line, Tumor; Chromatography, High Pressure Liquid; Reproducibility of Results; Spermidine; Spermine; Substrate Specificity | 2008 |
Involvement of polyamines in the post-anthesis development of inferior and superior spikelets in rice.
Topics: Adenosylmethionine Decarboxylase; Carboxy-Lyases; Flowering Tops; Genotype; Glucose-1-Phosphate Adenylyltransferase; Glucosyltransferases; Isopentenyladenosine; Oryza; Polyamines; Spermidine; Spermidine Synthase; Spermine; Starch Synthase; Zeatin | 2008 |
Excretion of polyamines in alfalfa and tobacco suspension-cultured cells and its possible role in maintenance of intracellular polyamine contents.
Topics: Amine Oxidase (Copper-Containing); Cadaverine; Carboxy-Lyases; Cell Culture Techniques; Medicago sativa; Nicotiana; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 2008 |
Effects of polyamines and polyamine biosynthetic inhibitors on mitotic activity of Allium cepa root tips.
Topics: Cycloheximide; Eflornithine; Enzyme Inhibitors; Meristem; Mitoguazone; Mitosis; Onions; Polyamines; Protein Synthesis Inhibitors; Putrescine; Spermidine; Spermine | 2008 |
[Effects of salt stress on cucumber seedlings root growth and polyamine metabolism].
Topics: Adenosylmethionine Decarboxylase; Carboxy-Lyases; Cucumis sativus; Ornithine Decarboxylase; Plant Roots; Polyamines; Seedlings; Sodium Chloride; Spermidine; Spermine | 2008 |
Adenovirus-mediated expression of SSAT inhibits colorectal cancer cell growth in vitro.
Topics: Acetyltransferases; Adenoviridae; Base Sequence; Cell Line; Colorectal Neoplasms; DNA, Complementary; Gene Expression; Genetic Vectors; Green Fluorescent Proteins; HT29 Cells; Humans; Kidney; Molecular Sequence Data; Plasmids; Spermidine; Spermine; Transfection | 2008 |
The alpha9beta1 integrin enhances cell migration by polyamine-mediated modulation of an inward-rectifier potassium channel.
Topics: Animals; Cell Movement; CHO Cells; Cricetinae; Cricetulus; Fibroblasts; Gene Expression Regulation; Integrins; Ligands; Mice; Polyamines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Spermidine; Spermine | 2008 |
Letter: characterisation and identification of spermine and spermidine derivatives in Microdesmis keayana and Microdesmis puberula roots by electrospray ionisation tandem mass spectrometry and high-performance liquid chromatography/electrospray ionisation
Topics: Chromatography, Liquid; Medicine, Traditional; Plant Roots; Spectrometry, Mass, Electrospray Ionization; Spermidine; Spermine; Tandem Mass Spectrometry | 2008 |
Comparative physiological and molecular responses of a common aromatic indica rice cultivar to high salinity with non-aromatic indica rice cultivars.
Topics: Blotting, Western; Catalase; Chlorophyll; Cysteine; Gene Expression Regulation, Plant; Lipid Peroxidation; Lipoxygenase; Malondialdehyde; Oryza; Peroxidase; Plant Roots; Plant Shoots; Proline; Putrescine; Reverse Transcriptase Polymerase Chain Reaction; Sodium Chloride; Spermidine; Spermine | 2008 |
Molecular dynamics simulation of multivalent-ion mediated attraction between DNA molecules.
Topics: Biogenic Polyamines; Computer Simulation; DNA; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Putrescine; Spermidine; Spermine; Thermodynamics; Water | 2008 |
Spermine-induced morphogenesis and effect of partial immersion system on the shoot cultures of banana.
Topics: Agriculture; Arginine; Eflornithine; Morphogenesis; Musa; Plant Shoots; Putrescine; Spermidine; Spermine | 2008 |
Intracellular Mg2+ is a voltage-dependent pore blocker of HCN channels.
Topics: Animals; Binding Sites; Cyclic Nucleotide-Gated Cation Channels; Dose-Response Relationship, Drug; Edetic Acid; Electrophysiology; Female; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Intracellular Space; Ion Channel Gating; Ion Channels; Magnesium; Membrane Potentials; Mice; Models, Biological; Mutagenesis, Site-Directed; Mutation; Oocytes; Patch-Clamp Techniques; Potassium Channels; Spermidine; Spermine; Time Factors; Xenopus laevis | 2008 |
Evolutionary diversification in polyamine biosynthesis.
Topics: Animals; Evolution, Molecular; Humans; Methyltransferases; Models, Biological; Models, Chemical; Models, Genetic; Phylogeny; Polyamines; Putrescine; Spermidine; Spermidine Synthase; Spermine; Spermine Synthase | 2008 |
Role of putrescine on androgen-elicited positive inotropism in the left atrium of rats.
Topics: Adrenergic beta-Agonists; Androgens; Animals; Atrial Function; Cardiotonic Agents; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Dihydrotestosterone; Eflornithine; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine | 2008 |
Inhibition of root growth and polyamine metabolism in sunflower (Helianthus annuus) seedlings under cadmium and copper stress.
Topics: Cadmium; Copper; Helianthus; Plant Roots; Polyamines; Putrescine; Seedlings; Spermidine; Spermine | 2008 |
The crystal structure of spermidine/spermine N1-acetyltransferase in complex with spermine provides insights into substrate binding and catalysis.
Topics: Acetyl Coenzyme A; Acetyltransferases; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Crystallography, X-Ray; Hydrogen-Ion Concentration; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Sequence Alignment; Spermidine; Spermine; Structure-Activity Relationship | 2008 |
A putative peroxisomal polyamine oxidase, AtPAO4, is involved in polyamine catabolism in Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Plant; Genes, Plant; Mutagenesis, Insertional; Oligonucleotide Array Sequence Analysis; Oxidoreductases Acting on CH-NH Group Donors; Peroxisomes; Plant Roots; Polyamine Oxidase; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Plant; Sequence Alignment; Spermidine; Spermine; Substrate Specificity | 2008 |
Putrescine modulation of acute activation of the beta-adrenergic system in the left atrium of rat.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Chromatography, High Pressure Liquid; Cyclic AMP; Dihydroalprenolol; Eflornithine; Enzyme Inhibitors; Heart; Heart Atria; Isoproterenol; Male; Membranes; Myocardium; Putrescine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Spermidine; Spermine | 2008 |
Nitrate supply induces changes in polyamine content and ethylene production in wheat plants grown with ammonium.
Topics: Biomass; Ethylenes; Nitrates; Perchlorates; Plant Roots; Plant Shoots; Polyamines; Putrescine; Quaternary Ammonium Compounds; Solubility; Spermidine; Spermine; Time Factors; Triticum | 2009 |
Endogenous polyamines regulate cortical neuronal excitability by blocking voltage-gated Na+ channels.
Topics: Action Potentials; Animals; Cerebral Cortex; Ion Channel Gating; Mice; Neurons; Patch-Clamp Techniques; Polyamines; Sodium Channel Blockers; Sodium Channels; Spermidine; Spermine; Tetrodotoxin | 2008 |
Synthesis and application of molecular probe for detection of hydroxyl radicals produced by Na(125)I and gamma-rays in aqueous solution.
Topics: Coumarins; Fluorescent Dyes; Gamma Rays; Hydrogen-Ion Concentration; Hydroxyl Radical; Iodine Radioisotopes; Molecular Probes; Nucleic Acid Conformation; Oligonucleotides; Sodium Iodide; Solutions; Spermidine; Spermine; Water | 2008 |
[Effects of NaCl stress on free polyamines content and reactive oxygen species level in pumpkin roots].
Topics: Cucurbita; Plant Roots; Polyamines; Putrescine; Reactive Oxygen Species; Sodium Chloride; Spermidine; Spermine | 2008 |
Abrupt transition from a free, repulsive to a condensed, attractive DNA phase, induced by multivalent polyamine cations.
Topics: Cations; DNA; Scattering, Small Angle; Solutions; Spermidine; Spermine; Thermodynamics; X-Ray Diffraction | 2008 |
Effects of Lactobacillus rhamnosus GG on proliferation and polyamine metabolism in HGC-27 human gastric and DLD-1 colonic cancer cell lines.
Topics: Biogenic Polyamines; Biosynthetic Pathways; Cell Extracts; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cytoplasm; Dose-Response Relationship, Drug; Humans; Lacticaseibacillus rhamnosus; Ornithine Decarboxylase; Probiotics; Putrescine; Spermidine; Spermine; Stomach Neoplasms | 2009 |
The in vitro nuclear aggregates of polyamines.
Topics: Buffers; Chromatography, Gel; DNA; Humans; Polyamines; Putrescine; Spermidine; Spermine | 2009 |
Elevated polyamines induce c-MYC overexpression by perturbing quadruplex-WC duplex equilibrium.
Topics: Circular Dichroism; Fluorescence Resonance Energy Transfer; G-Quadruplexes; Genes, myc; HeLa Cells; Humans; Nucleic Acid Denaturation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Spermidine; Spermine; Thermodynamics | 2009 |
Structure-activity relationships of lipopolysaccharide sequestration in N-alkylpolyamines.
Topics: Cell Line; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Design; Endotoxins; Humans; Lipopolysaccharides; Molecular Structure; Polyamines; Sepsis; Solubility; Spermidine; Spermine; Structure-Activity Relationship | 2009 |
Behavioral and neurochemical effects of acute putrescine depletion by difluoromethylornithine in rats.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Eflornithine; Enzyme Inhibitors; Exploratory Behavior; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Maze Learning; Memory; Memory Disorders; Motor Activity; Prefrontal Cortex; Putrescine; Rats; Rats, Sprague-Dawley; Space Perception; Spatial Behavior; Spermidine; Spermine | 2009 |
Waterlogging tolerance of Welsh onion (Allium fistulosum L.) enhanced by exogenous spermidine and spermine.
Topics: Adaptation, Physiological; Allium; Antioxidants; Ascorbate Peroxidases; Chlorophyll; Floods; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Oxygen; Peroxidases; Photosynthesis; Plant Leaves; Plant Roots; Proline; Spermidine; Spermine; Superoxides; Water | 2009 |
Determination of dansylated polyamines in red blood cells by liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Dansyl Compounds; Erythrocytes; Humans; Polyamines; Putrescine; Spectrometry, Fluorescence; Spermidine; Spermine; Tandem Mass Spectrometry | 2009 |
Effects of polyamines on the DNA-reactive properties of dimeric mithramycin complexed with cobalt(II): implications for anticancer therapy.
Topics: Antibiotics, Antineoplastic; Binding, Competitive; Cell Line, Tumor; Cell Survival; Circular Dichroism; Cobalt; Dimerization; DNA, Bacterial; DNA, Superhelical; Humans; Mitoguazone; Plicamycin; Spermidine; Spermine | 2009 |
Kinetin affects the level of chloroplast polyamines and transglutaminase activity during senescence of barley leaves.
Topics: Amination; Apoptosis; Chlorophyll Binding Proteins; Chloroplasts; Hordeum; Kinetin; Light-Harvesting Protein Complexes; Photosystem II Protein Complex; Plant Leaves; Plant Proteins; Polyamines; Protein Processing, Post-Translational; Putrescine; Spermidine; Spermine; Thylakoids; Transglutaminases | 2009 |
Polyamine anabolic/catabolic regulation along the woody grapevine plant axis.
Topics: Adenosylmethionine Decarboxylase; Gene Expression Regulation, Plant; Hydrogen Peroxide; Peroxidase; Polyamines; Putrescine; Signal Transduction; Spermidine; Spermidine Synthase; Spermine; Vitis | 2009 |
Effects of dietary polyamines at physiologic doses in early-weaned piglets.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Diet; Female; Food, Formulated; gamma-Glutamyltransferase; Intestinal Mucosa; Intestine, Small; Jejunum; Male; Milk; Spermidine; Spermine; Swine; Weaning | 2009 |
Characterization of spermidine transport system in a cyanobacterium,synechocystis sp. PCC 6803.
Topics: Biological Transport, Active; Enzyme Inhibitors; Hydrogen-Ion Concentration; Ionophores; Membrane Potentials; Osmosis; Putrescine; Salt Tolerance; Spermidine; Spermine; Synechocystis | 2009 |
A quantitative GC-MS method for three major polyamines in postmortem brain cortex.
Topics: Analytic Sample Preparation Methods; Biogenic Polyamines; Brain Chemistry; Calibration; Electrons; Formic Acid Esters; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Molecular Structure; Putrescine; Reference Standards; Spermidine; Spermine; Suicide; Trifluoroacetic Acid | 2009 |
[Effects of exogenous spermidine and spermine on Celastrus orbiculatus antioxidant system under soil NaHCO3 stress].
Topics: Celastrus; Peroxidases; Sodium Bicarbonate; Soil; Spermidine; Spermine; Stress, Physiological; Superoxide Dismutase | 2009 |
Transgenic manipulation of a single polyamine in poplar cells affects the accumulation of all amino acids.
Topics: Amino Acids; Animals; Carbon; Cell Line; gamma-Aminobutyric Acid; Mice; Nitrogen; Ornithine; Ornithine Decarboxylase; Perchlorates; Plants, Genetically Modified; Populus; Putrescine; Solubility; Spermidine; Spermine; Statistics as Topic; Time Factors; Transgenes; Up-Regulation | 2010 |
Ion-blocking sites of the Kir2.1 channel revealed by multiscale modeling.
Topics: Animals; Computer Simulation; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Humans; Ion Channel Gating; Magnesium; Mice; Models, Molecular; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Protein Structure, Tertiary; Spermidine; Spermine; Static Electricity; Structural Homology, Protein; Thermodynamics | 2009 |
Intense correlation between brain infarction and protein-conjugated acrolein.
Topics: Acetylcysteine; Acrolein; Animals; Brain; Carrier Proteins; Disease Models, Animal; Down-Regulation; Free Radical Scavengers; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Photochemistry; Rose Bengal; Spermidine; Spermine; Time Factors; Up-Regulation | 2009 |
Abscisic acid has contrasting effects on salt excretion and polyamine concentrations of an inland and a coastal population of the Mediterranean xero-halophyte species Atriplex halimus.
Topics: Abscisic Acid; Atriplex; Betaine; Biogenic Polyamines; Plant Leaves; Plant Roots; Plant Shoots; Proline; Putrescine; Pyridones; Salt Tolerance; Sodium Chloride; Spermidine; Spermine; Water-Electrolyte Balance | 2009 |
Microarray studies on the genes responsive to the addition of spermidine or spermine to a Saccharomyces cerevisiae spermidine synthase mutant.
Topics: Down-Regulation; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Oligonucleotide Array Sequence Analysis; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spermidine; Spermidine Synthase; Spermine; Up-Regulation | 2009 |
Polyamine-rich food decreases age-associated pathology and mortality in aged mice.
Topics: Aging; Animals; Diet; Longevity; Male; Mice; Polyamines; Spermidine; Spermine | 2009 |
The effect of experimental conditions on the detection of spermine in cell extracts and tissues.
Topics: Animals; Cattle; Cell Extracts; Cell Line, Tumor; Humans; Magnetic Resonance Spectroscopy; Male; Metabolome; Mice; Putrescine; Solutions; Spermidine; Spermine; Tissue Extracts; Transplantation, Heterologous | 2010 |
Polynuclear palladium complexes with biogenic polyamines: AFM and voltammetric characterization.
Topics: Adsorption; Carbon; Chelating Agents; Electrochemistry; Electrodes; Glass; Hydrogen-Ion Concentration; Ligands; Microscopy, Atomic Force; Organometallic Compounds; Oxidation-Reduction; Palladium; Spermidine; Spermine | 2010 |
Augmented bladder urothelial polyamine signaling and block of BK channel in the pathophysiology of overactive bladder syndrome.
Topics: Cells, Cultured; Eflornithine; Electrophysiology; Enzyme Inhibitors; Female; Fluorescent Antibody Technique; Humans; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Ornithine Decarboxylase; Polyamines; Signal Transduction; Spermidine; Spermine; Urinary Bladder; Urinary Bladder, Overactive; Urothelium; Young Adult | 2009 |
Polyamine-promoted autoactivation of plasma hyaluronan-binding protein.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Blood Coagulation; Carmine; Cell Line, Tumor; Enzyme Activation; Humans; Melanoma, Experimental; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Polyamines; Protein Binding; Protein Interaction Domains and Motifs; Protein Interaction Mapping; Protein Structure, Tertiary; Putrescine; Serine Endopeptidases; Spermidine; Spermine; Transfection | 2010 |
Influence of breast milk polyamines on suckling rat immune system maturation.
Topics: Animals; Immune System; Intestine, Small; Lymphocytes; Milk; Rats; Rats, Wistar; Spermidine; Spermine | 2010 |
Development of highly sensitive and selective molecules for detection of spermidine and spermine.
Topics: Anions; Colorimetry; Kinetics; Molecular Probe Techniques; Molecular Probes; Rhodamines; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spermidine; Spermine | 2009 |
Spermidine regulates insulin synthesis and cytoplasmic Ca(2+) in mouse beta-TC6 insulinoma cells.
Topics: Animals; Calcium; Carbachol; Cell Line, Tumor; Cyclohexylamines; Enzyme Inhibitors; Gene Expression; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Nicotine; Potassium; Protein Biosynthesis; Spermidine; Spermidine Synthase; Spermine; Spermine Synthase | 2009 |
Polyamines: naturally occurring small molecule modulators of electrostatic protein-protein interactions.
Topics: Adrenodoxin; Animals; Binding Sites; Binding, Competitive; Catalysis; Cholesterol Side-Chain Cleavage Enzyme; Electron Transport; Ferredoxin-NADP Reductase; Humans; Kinetics; Models, Molecular; Mutation; Oxidation-Reduction; Polyamines; Protein Binding; Protein Structure, Tertiary; Proteins; Putrescine; Spermidine; Spermine; Static Electricity | 2010 |
[Determination of five biogenic amines in source water by ion chromatography].
Topics: Biogenic Amines; Cadaverine; Chromatography, Ion Exchange; Fresh Water; Histamine; Putrescine; Spermidine; Spermine; Water Pollutants, Chemical | 2009 |
Down-regulation of hypusine biosynthesis in Plasmodium by inhibition of S-adenosyl-methionine-decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Down-Regulation; Enzyme Inhibitors; Eukaryotic Translation Initiation Factor 5A; Gene Expression Regulation, Enzymologic; Humans; Indans; Kinetics; Malaria, Falciparum; Mice; Mice, Inbred C57BL; Peptide Initiation Factors; Plasmodium falciparum; Protozoan Proteins; Putrescine; RNA-Binding Proteins; Spermidine; Spermine | 2010 |
Polyamine catabolism is enhanced after traumatic brain injury.
Topics: Acetyltransferases; Animals; Biogenic Polyamines; Biomarkers; Brain; Brain Chemistry; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Functional Laterality; Hippocampus; Immunohistochemistry; Metabolism; Neurons; Organ Culture Techniques; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spermidine; Spermine; Time Factors; Up-Regulation | 2010 |
Factor VII activating protease (FSAP): caught in the cross-fire between polycations and polyanions.
Topics: Allosteric Regulation; Anions; Binding Sites; Blood Coagulation; Cations; Enzyme Activation; Humans; Polyamines; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Tertiary; Putrescine; Serine Endopeptidases; Spermidine; Spermine | 2010 |
Editorial comment.
Topics: Carcinoma, Renal Cell; Humans; Kidney Neoplasms; Nephrectomy; Prognosis; Spermidine; Spermine; Survival Rate | 2010 |
The prognostic value of erythrocyte polyamine in the post-nephrectomy stratification of renal cell carcinoma specific mortality.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Renal Cell; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Nephrectomy; Prognosis; Prospective Studies; Retrospective Studies; Spermidine; Spermine; Survival Rate; Young Adult | 2010 |
Central L-ornithine, but not polyamines, induces a hypnotic effect in neonatal chicks under acute stress.
Topics: Animals; Behavior, Animal; Chickens; Hypnotics and Sedatives; Injections, Intraventricular; Male; Ornithine; Polyamines; Posture; Putrescine; Social Isolation; Spermidine; Spermine; Stress, Psychological; Time Factors; Vocalization, Animal | 2010 |
A high-affinity putrescine-cadaverine transporter from Trypanosoma cruzi.
Topics: Cadaverine; Cell Membrane; Cytoplasm; DNA, Protozoan; Membrane Transport Proteins; Microscopy, Fluorescence; Microscopy, Immunoelectron; Molecular Sequence Data; Protozoan Proteins; Putrescine; Sequence Analysis, DNA; Spermidine; Spermine; Substrate Specificity; Trypanosoma cruzi | 2010 |
Putrescine accumulation confers drought tolerance in transgenic Arabidopsis plants over-expressing the homologous Arginine decarboxylase 2 gene.
Topics: Adaptation, Physiological; Arabidopsis; Arabidopsis Proteins; Carboxy-Lyases; Droughts; Gene Expression; Genes, Plant; Plant Stomata; Plant Transpiration; Plants, Genetically Modified; Putrescine; Spermidine; Spermine | 2010 |
Differential and functional interactions emphasize the multiple roles of polyamines in plants.
Topics: Fruit; Gene Expression Profiling; Metabolome; Models, Biological; Plants, Genetically Modified; Putrescine; Solanum lycopersicum; Spermidine; Spermine | 2010 |
The prognostic value of erythrocyte polyamines in the preoperative evaluation of patients with renal cell carcinoma.
Topics: Aged; Biomarkers, Tumor; Carcinoma, Renal Cell; Disease-Free Survival; Erythrocytes; Female; Humans; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Nephrectomy; Preoperative Care; Prognosis; Spermidine; Spermine | 2010 |
[Prognostic value of erythrocyte polyamines levels in renal cell carcinoma. Prospective study in 418 cases].
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Renal Cell; Erythrocytes; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Prognosis; Prospective Studies; Spermidine; Spermine; Young Adult | 2010 |
Polyamine biosynthesis in Phytomonas: biochemical characterisation of a very unstable ornithine decarboxylase.
Topics: Enzyme Stability; Ornithine Decarboxylase; Polyamines; Protozoan Proteins; Putrescine; Spermidine; Spermine; Trypanosomatina | 2010 |
Enigmas of biosyntheses of unusual polyamines in an extreme thermophile, Thermus thermophilus.
Topics: Biosynthetic Pathways; Plants; Polyamines; Spermidine; Spermine; Thermus thermophilus | 2010 |
Polyamines can increase resistance of Neisseria gonorrhoeae to mediators of the innate human host defense.
Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Biogenic Polyamines; Cadaverine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Female; Gene Deletion; Gonorrhea; Humans; Immunity, Innate; Immunoblotting; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Putrescine; Spermidine; Spermine | 2010 |
Combination effects of platinum drugs and N1, N11 diethylnorspermine on spermidine/spermine N1-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants.
Topics: Acetyltransferases; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Induction; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Polyamines; Putrescine; Spermidine; Spermine | 2011 |
Putrescine differently influences the effect of salt stress on polyamine metabolism and ethylene synthesis in rice cultivars differing in salt resistance.
Topics: Biomass; Cations, Monovalent; Ethylenes; Gene Expression Regulation, Plant; Malondialdehyde; Oryza; Osmosis; Plant Leaves; Plant Proteins; Plant Roots; Plant Shoots; Potassium; Putrescine; RNA, Messenger; Salt Tolerance; Sodium; Sodium Chloride; Spermidine; Spermine; Stress, Physiological; Water | 2010 |
Continuous oxidative stress due to activation of polyamine catabolism accelerates aging and protects against hepatotoxic insults.
Topics: Acetyltransferases; Aging; Animals; Carbon Tetrachloride; Liver; Male; Mice; Mice, Transgenic; Oxidative Stress; Polyamines; Putrescine; Spermidine; Spermine; Thioacetamide; Transgenes; Tumor Suppressor Protein p53; Up-Regulation | 2011 |
Overexpression of yeast spermidine synthase impacts ripening, senescence and decay symptoms in tomato.
Topics: Carotenoids; Cell Membrane; Cell Wall; Ethylenes; Fruit; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Immunoblotting; Lycopene; Plant Leaves; Plant Proteins; Plants, Genetically Modified; Putrescine; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae Proteins; Solanum lycopersicum; Spermidine; Spermidine Synthase; Spermine; Time Factors; Transgenes | 2010 |
A multivariate analysis of the effects of aging on glutamate, GABA and arginine metabolites in the rat vestibular nucleus.
Topics: Aging; Animals; Arginine; Cerebellum; Cluster Analysis; gamma-Aminobutyric Acid; Glutamic Acid; Male; Models, Animal; Multivariate Analysis; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Vestibular Nuclei | 2010 |
Short-term UV-B and UV-C radiations preferentially decrease spermidine contents and arginine decarboxylase transcript levels of Synechocystis sp. PCC 6803.
Topics: Carboxy-Lyases; Carotenoids; Chlorophyll; Gene Expression Regulation, Bacterial; Putrescine; RNA, Messenger; Spermidine; Spermine; Synechocystis; Ultraviolet Rays | 2011 |
Amelioration of salinity stress by exogenously applied spermidine or spermine in three varieties of indica rice differing in their level of salt tolerance.
Topics: Antioxidants; Cations; Chlorophyll; Hydrogen Peroxide; Lipid Peroxidation; Oryza; Oxidative Stress; Peptide Hydrolases; Plant Proteins; Plant Roots; Plant Shoots; Proline; Protein Carbonylation; Salt Tolerance; Seedlings; Sodium Chloride; Spermidine; Spermine | 2011 |
Probing tRNA interaction with biogenic polyamines.
Topics: Binding Sites; Biogenic Polyamines; Cobalt; Electrophoresis, Capillary; Kinetics; Models, Molecular; Nucleic Acid Conformation; Putrescine; RNA Stability; RNA, Fungal; RNA, Transfer; Saccharomyces cerevisiae; Spectroscopy, Fourier Transform Infrared; Spermidine; Spermine | 2010 |
Targeting the polyamine transport system with benzazepine- and azepine-polyamine conjugates.
Topics: Animals; Antineoplastic Agents; Azepines; Benzazepines; Biological Transport; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Drug Screening Assays, Antitumor; Leukemia L1210; Polyamines; Spermidine; Spermine; Structure-Activity Relationship | 2010 |
Early activation of wheat polyamine biosynthesis during Fusarium head blight implicates putrescine as an inducer of trichothecene mycotoxin production.
Topics: Amino Acids; Biosynthetic Pathways; Carboxy-Lyases; DNA, Complementary; Fusarium; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Host-Pathogen Interactions; Molecular Sequence Data; Mycotoxins; Ornithine Decarboxylase; Plant Diseases; Plant Proteins; Polyamines; Putrescine; Sequence Analysis, DNA; Spermidine; Spermine; Trichothecenes; Triticum | 2010 |
The structure of maize polyamine oxidase K300M mutant in complex with the natural substrates provides a snapshot of the catalytic mechanism of polyamine oxidation.
Topics: Catalysis; Crystallography, X-Ray; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Plant Proteins; Polyamine Oxidase; Polyamines; Protein Structure, Secondary; Spermidine; Spermine; Zea mays | 2011 |
LPS-induced CCL2 expression and macrophage influx into the murine central nervous system is polyamine-dependent.
Topics: Animals; Cells, Cultured; Central Nervous System; Chemokine CCL2; Injections, Intraventricular; Interferon-gamma; Lipopolysaccharides; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroglia; Neurons; Ornithine Decarboxylase; Putrescine; Receptors, Immunologic; Spermidine; Spermine; Triggering Receptor Expressed on Myeloid Cells-1 | 2011 |
Spermidine delays eye lens opacification in vitro by suppressing transglutaminase-catalyzed crystallin cross-linking.
Topics: Animals; Calcium; Capsule Opacification; Cataract; Crystallins; Disease Models, Animal; Lens, Crystalline; Rabbits; Spermidine; Spermine; Transglutaminases | 2011 |
Polyamines stimulate non-photochemical quenching of chlorophyll a fluorescence in Scenedesmus obliquus.
Topics: Biogenic Polyamines; Chlorophyll; Chlorophyll A; Fluorescence; Light-Harvesting Protein Complexes; Models, Molecular; Plant Proteins; Protein Structure, Tertiary; Scenedesmus; Spermidine; Spermine | 2011 |
Translational recoding as a feedback controller: systems approaches reveal polyamine-specific effects on the antizyme ribosomal frameshift.
Topics: Binding Sites; Codon, Terminator; Feedback, Physiological; Frameshifting, Ribosomal; Gene Deletion; Gene Expression Regulation, Fungal; Models, Genetic; Mutation; Polyamines; Putrescine; Ribosomes; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spermidine; Spermine | 2011 |
Identification, chemical synthesis, and biological functions of unusual polyamines produced by extreme thermophiles.
Topics: Biochemistry; Biosynthetic Pathways; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Nucleic Acids; Plasmids; Polyamines; Protein Biosynthesis; Quaternary Ammonium Compounds; Recombination, Genetic; Spermidine; Spermine; Thermus thermophilus | 2011 |
Procedures to evaluate the importance of dietary polyamines.
Topics: Acetonitriles; Animals; Chemical Precipitation; Chromatography, High Pressure Liquid; Complex Mixtures; Dansyl Compounds; Diet; Food Analysis; Perchlorates; Polyamines; Putrescine; Reference Standards; Solubility; Solutions; Spermidine; Spermine; Toluene | 2011 |
High-resolution capillary gas chromatography in combination with mass spectrometry for quantification of three major polyamines in postmortem brain cortex.
Topics: Brain; Calibration; Cerebral Cortex; Formic Acid Esters; Gas Chromatography-Mass Spectrometry; Humans; Polyamines; Postmortem Changes; Putrescine; Reference Standards; Spermidine; Spermine; Statistics as Topic | 2011 |
Spermine synthase deficiency resulting in X-linked intellectual disability (Snyder-Robinson syndrome).
Topics: Enzyme Assays; Female; Genes, X-Linked; Humans; Intellectual Disability; Male; Mental Retardation, X-Linked; Mutation; Spermidine; Spermine; Spermine Synthase | 2011 |
Fluorescent substrates for polyamine catabolic enzymes and transport.
Topics: Acetyltransferases; Animals; Biochemistry; Biological Transport; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dansyl Compounds; Enzyme Assays; Fluorescent Dyes; Humans; Liver; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Rats; Spermidine; Spermine; Substrate Specificity | 2011 |
Atnoa1 mutant Arabidopsis plants induce compensation mechanisms to reduce the negative effects of the mutation.
Topics: Acclimatization; Arabidopsis; Arabidopsis Proteins; Chlorophyll; Cold Temperature; Fluorescence; Genotype; Mutation; Nitric Oxide Synthase; Photoperiod; Plant Leaves; Salicylic Acid; Spermidine; Spermine | 2011 |
Photodynamic effects of porphyrin-polyamine conjugates in human breast cancer and keratinocyte cell lines.
Topics: Apoptosis; Breast Neoplasms; Cell Line; Cell Line, Tumor; Female; Humans; Keratinocytes; Photochemistry; Photosensitizing Agents; Phototherapy; Polyamines; Porphyrins; Spermidine; Spermine; Stereoisomerism | 2011 |
[Determination of polyamines in various biological media].
Topics: Adolescent; Adult; Electrophoresis; Fertility; Humans; Male; Polyamines; Spermatozoa; Spermidine; Spermine; Young Adult | 2011 |
Identification and characterization of a novel spermidine/spermine acetyltransferase encoded by gene ste26 from Streptomyces sp. 139.
Topics: Acetyltransferases; Bacterial Proteins; Cloning, Molecular; Hydrogen-Ion Concentration; Molecular Sequence Data; Polylysine; Recombinant Proteins; Spermidine; Spermine; Streptomyces; Temperature | 2011 |
Regulation of cyclin-dependent kinase 4 translation through CUG-binding protein 1 and microRNA-222 by polyamines.
Topics: Animals; CELF1 Protein; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase 4; Eflornithine; Enzyme Assays; Epithelial Cells; Gene Expression Regulation; Gene Silencing; Genes, Reporter; Intestinal Mucosa; Luciferases, Firefly; MicroRNAs; Open Reading Frames; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Protein Binding; Protein Biosynthesis; Putrescine; Rats; Recombinant Proteins; RNA-Binding Proteins; RNA, Messenger; Spermidine; Spermine; Transcription, Genetic | 2011 |
Modification of secondary head-forming activity of microinjected ∆β-catenin mRNA by co-injected spermine and spermidine in Xenopus early embryos.
Topics: Animals; beta Catenin; Microinjections; RNA, Messenger; Spermidine; Spermine; Xenopus | 2012 |
Effect of chemical chaperones on glucose-induced lysozyme modifications.
Topics: Animals; Chickens; Dimerization; Glucose; Glycosylation; Molecular Chaperones; Muramidase; Protein Binding; Protein Conformation; Spermidine; Spermine | 2011 |
The evolution of a superbug: how Staphylococcus aureus overcomes its unique susceptibility to polyamines.
Topics: Acetyltransferases; Bacterial Proteins; Spermidine; Spermine; Staphylococcus aureus | 2011 |
Arginine catabolic mobile element encoded speG abrogates the unique hypersensitivity of Staphylococcus aureus to exogenous polyamines.
Topics: Acetyltransferases; Arginine; Bacterial Proteins; Microbial Sensitivity Tests; Spermidine; Spermine; Staphylococcus aureus | 2011 |
Na⁺,K⁺-ATPase activity in the posterior gills of the blue crab, Callinectes ornatus (Decapoda, Brachyura): modulation of ATP hydrolysis by the biogenic amines spermidine and spermine.
Topics: Adenosine Triphosphate; Animals; Brachyura; Cations; Enzyme Activation; Gills; Hydrolysis; Kinetics; Ouabain; Polyamines; Sodium-Potassium-Exchanging ATPase; Spermidine; Spermine | 2011 |
Association between remote organ injury and tissue polyamine homeostasis in acute experimental pancreatitis - treatment with a polyamine analogue bismethylspermine.
Topics: Acetyltransferases; Animals; Creatinine; Disease Models, Animal; Dose-Response Relationship, Drug; Kidney; Liver; Lung; Male; Pancreatitis; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Taurodeoxycholic Acid | 2011 |
Influence of histone tails and H4 tail acetylations on nucleosome-nucleosome interactions.
Topics: Acetylation; Animals; Calcium; Cobalt; Computer Simulation; Histones; Humans; Magnesium; Mutation; Nucleosomes; Protein Binding; Spermidine; Spermine; Xenopus laevis; Xenopus Proteins | 2011 |
The natural polyamines spermidine and spermine prevent bone loss through preferential disruption of osteoclastic activation in ovariectomized mice.
Topics: Administration, Oral; Animals; Blotting, Western; Bone Resorption; Cell Differentiation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred Strains; NF-kappa B; Osteoclasts; Osteoporosis; Ovariectomy; RANK Ligand; Spermidine; Spermine; Transcription, Genetic | 2012 |
Spermine synthase overexpression in vivo does not increase susceptibility to DMBA/TPA skin carcinogenesis or Min-Apc intestinal tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenosylmethionine Decarboxylase; Animals; Colon; Disease Models, Animal; Epidermis; Gene Expression Regulation, Enzymologic; Genes, APC; Intestinal Neoplasms; Mice; Mice, Transgenic; Ornithine Decarboxylase; Polyamines; Skin Neoplasms; Spermidine; Spermine; Spermine Synthase; Tetradecanoylphorbol Acetate | 2012 |
Revisiting inward rectification: K ions permeate through Kir2.1 channels during high-affinity block by spermidine.
Topics: Amino Acid Substitution; Animals; Binding Sites; Electrophysiological Phenomena; Female; In Vitro Techniques; Kinetics; Membrane Potentials; Models, Biological; Mutagenesis, Site-Directed; Oocytes; Potassium Channels, Inwardly Rectifying; Recombinant Proteins; Spermidine; Spermine; Xenopus laevis | 2012 |
Resolution of microscopic protonation enthalpies of polyprotic molecules by means of cluster expansions.
Topics: Protons; Spermidine; Spermine; Temperature; Thermodynamics | 2012 |
Infant formula supplemented with polyamines alters the intestinal microbiota in neonatal BALB/cOlaHsd mice.
Topics: Animals; Animals, Newborn; Bifidobacterium; Dose-Response Relationship, Drug; Enterococcus; Female; Infant Formula; Intestines; Lactobacillus; Male; Metagenome; Mice; Mice, Inbred BALB C; Polyamines; Putrescine; Spermidine; Spermine; Weaning | 2012 |
Effects of salt stress on the structure and function of the photosynthetic apparatus in Cucumis sativus and its protection by exogenous putrescine.
Topics: Chlorophyll; Chloroplasts; Cucumis sativus; Fluorescence; Mesophyll Cells; Photochemistry; Photosynthesis; Photosystem II Protein Complex; Plant Leaves; Polyamines; Putrescine; Seedlings; Sodium Chloride; Spermidine; Spermine; Stress, Physiological; Thylakoids | 2012 |
Hippocampal polyamine levels and transglutaminase activity are paralleling spatial memory retrieval in the C57BL/6J mouse.
Topics: Animals; Hippocampus; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Polyamines; Spatial Behavior; Spermidine; Spermine; Transglutaminases | 2012 |
Effect of exogenous spermidine on polyamine content and metabolism in tomato exposed to salinity-alkalinity mixed stress.
Topics: Adenosylmethionine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Salinity; Sodium Chloride; Solanum lycopersicum; Spermidine; Spermine | 2012 |
[Research on the DNA condensation properties by ultraviolet spectrum].
Topics: Animals; Cattle; Chlorides; Cobalt; DNA; Spectrum Analysis; Spermidine; Spermine | 2012 |
γ-glutamyl Spermine Synthetase PauA2 as a potential target of antibiotic development against Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Spermidine; Spermine; Spermine Synthase | 2012 |
Spermidine and spermine are enriched in whole blood of nona/centenarians.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Male; Metabolic Networks and Pathways; Methionine; Middle Aged; Spermidine; Spermine | 2012 |
Graphene oxide-based hydrogels to make metal nanoparticle-containing reduced graphene oxide-based functional hybrid hydrogels.
Topics: Ascorbic Acid; Graphite; Hydrogels; Metal Nanoparticles; Oxides; Spermidine; Spermine | 2012 |
Role of ornithine decarboxylase in regulation of estrogen receptor alpha expression and growth in human breast cancer cells.
Topics: Acetyltransferases; Breast Neoplasms; Cell Proliferation; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Proteins; Signal Transduction; Spermidine; Spermine | 2012 |
Polyamine metabolism during exponential growth transition in Scots pine embryogenic cell culture.
Topics: Cell Proliferation; Cell Survival; Cells, Cultured; DNA, Complementary; Electric Conductivity; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant; Hydrogen-Ion Concentration; Pinus sylvestris; Plant Somatic Embryogenesis Techniques; Polyamines; Putrescine; RNA, Plant; Sequence Analysis, DNA; Spermidine; Spermine; Stress, Physiological | 2012 |
Intracellular polyamines enhance astrocytic coupling.
Topics: Animals; Astrocytes; CA1 Region, Hippocampal; Carbenoxolone; Cell Communication; Connexin 43; Female; Fluorescent Dyes; Gap Junctions; Giant Cells; Intracellular Fluid; Isoquinolines; Membrane Potentials; Rats; Rats, Sprague-Dawley; Spermidine; Spermine | 2012 |
The polyamine spermine protects Arabidopsis from heat stress-induced damage by increasing expression of heat shock-related genes.
Topics: Adenosylmethionine Decarboxylase; Amino Acid Sequence; Arabidopsis; Gene Expression Regulation, Plant; Heat-Shock Proteins; Heat-Shock Response; Molecular Sequence Data; Mutation; Plants, Genetically Modified; Spermidine; Spermine; Spermine Synthase | 2013 |
Food polyamine and cardiovascular disease--an epidemiological study.
Topics: Cardiovascular Diseases; Diet; Fruit; Global Health; Gross Domestic Product; Humans; Linear Models; Obesity; Polyamines; Risk Factors; Smoking; Spermidine; Spermine; Vegetables | 2012 |
Biogenic polyamines spermine and spermidine activate RNA polymerase and inhibit RNA helicase of hepatitis C virus.
Topics: Enzyme Activation; Hepacivirus; Humans; Putrescine; RNA Helicases; RNA-Dependent RNA Polymerase; Spermidine; Spermine; Viral Nonstructural Proteins | 2012 |
Polyamines in human breast milk for preterm and term infants.
Topics: Breast Feeding; Female; Humans; Infant, Newborn; Infant, Premature; Lactation; Milk, Human; Polyamines; Pregnancy; Spermidine; Spermine | 2013 |
Depletion of cellular polyamines, spermidine and spermine, causes a total arrest in translation and growth in mammalian cells.
Topics: Acetyltransferases; Cell Proliferation; Gene Expression; Green Fluorescent Proteins; HEK293 Cells; HeLa Cells; Humans; Polyribosomes; Protein Biosynthesis; RNA, Messenger; Spermidine; Spermine | 2013 |
Suppression of LFA-1 expression by spermine is associated with enhanced methylation of ITGAL, the LFA-1 promoter area.
Topics: Cell Line; Eflornithine; Enzyme Inhibitors; Gene Expression Regulation; Humans; Leukocytes, Mononuclear; Lymphocyte Function-Associated Antigen-1; Methylation; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Promoter Regions, Genetic; Spermidine; Spermine | 2013 |
Dexamethasone decreases the spermidine and spermine concentrations and polyamine oxidase activity in rat thymus.
Topics: Animals; Dexamethasone; Electrophoresis; Glucocorticoids; Male; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Rats; Rats, Wistar; Spermidine; Spermine; Thymus Gland | 2013 |
Cellular polyamines promote amyloid-beta (Aβ) peptide fibrillation and modulate the aggregation pathways.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Humans; Peptide Fragments; Polyamines; Putrescine; Signal Transduction; Spermidine; Spermine | 2013 |
Ornithine: the overlooked molecule in the regulation of polyamine metabolism.
Topics: Animals; Arabidopsis; Biosynthetic Pathways; Cadaverine; Carbon Isotopes; Carboxy-Lyases; DNA, Complementary; Genetic Vectors; Mice; Ornithine; Ornithine Decarboxylase; Plants, Genetically Modified; Polyamines; Putrescine; Radioactivity; Spermidine; Spermine | 2013 |
Natural polyamine inhibits mouse skin inflammation and macrophage activation.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Edema; Interleukin-1beta; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Skin; Spermidine; Spermine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2013 |
Structure-activity relationships in aminosterol antibiotics: the effect of stereochemistry at the 7-OH group.
Topics: Anti-Bacterial Agents; Cholestanols; Escherichia coli; Liposomes; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Spermidine; Spermine; Stereoisomerism; Structure-Activity Relationship | 2013 |
Lower polyamine levels in breast milk of obese mothers compared to mothers with normal body weight.
Topics: Adult; Body Mass Index; Breast Feeding; Feeding Behavior; Female; Guidelines as Topic; Humans; Lactation; Milk, Human; Obesity; Pregnancy; Putrescine; Reference Values; Spermidine; Spermine | 2013 |
Elevated polyamines in urothelial cells from OAB subjects mediate oxotremorine-evoked rapid intracellular calcium rise and delayed acetylcholine release.
Topics: Acetylcholine; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Fluorescent Antibody Technique; Humans; Oxotremorine; Polyamines; Putrescine; Signal Transduction; Spermidine; Spermine; Urinary Bladder, Overactive; Urothelium | 2013 |
Polyamines inhibit porin-mediated fluoroquinolone uptake in mycobacteria.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Biological Transport, Active; Cadaverine; Cell Membrane Permeability; Culture Media; Dose-Response Relationship, Drug; Fluoroquinolones; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Mycobacterium bovis; Mycobacterium tuberculosis; Polyamines; Porins; Putrescine; Spermidine; Spermine | 2013 |
Biochemical characterization of Hpa2 and Hpa3, two small closely related acetyltransferases from Saccharomyces cerevisiae.
Topics: Acetylation; Acetyltransferases; Amino Acid Sequence; Amino Acids; Amino-Acid N-Acetyltransferase; Codon, Initiator; Electrophoresis, Polyacrylamide Gel; High Mobility Group Proteins; Histone Acetyltransferases; Histones; Isoenzymes; Lysine; Methionine; Molecular Sequence Data; Mutation; Protein Multimerization; Putrescine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spermidine; Spermine; Substrate Specificity | 2013 |
Exogenous polyamines promote osteogenic differentiation by reciprocally regulating osteogenic and adipogenic gene expression.
Topics: Adipogenesis; Alkaline Phosphatase; Bone Marrow Cells; Cell Differentiation; Cell Line; Cell Proliferation; Core Binding Factor Alpha 1 Subunit; Gene Expression Regulation, Developmental; Humans; Mesenchymal Stem Cells; Osteogenesis; Putrescine; Spermidine; Spermine | 2013 |
Biochemical and physiological responses of oil palm to bud rot caused by Phytophthora palmivora.
Topics: Antioxidants; Arecaceae; Carbon Dioxide; Chlorophyll; Palm Oil; Peroxidase; Phenylalanine Ammonia-Lyase; Photosynthesis; Phytophthora; Plant Diseases; Plant Oils; Putrescine; Spermidine; Spermine | 2013 |
Over-accumulation of putrescine induced by cyclohexylamine interferes with chromium accumulation and partially restores pollen tube growth in Actinidia deliciosa.
Topics: Actinidia; Calcium; Chromium; Cyclohexylamines; Pollen Tube; Putrescine; Reactive Oxygen Species; Spermidine; Spermine; Stress, Physiological | 2013 |
Binding of the biogenic polyamines to deoxyribonucleic acids of varying base composition: base specificity and the associated energetics of the interaction.
Topics: AT Rich Sequence; Base Composition; Biogenic Polyamines; Calorimetry, Differential Scanning; Circular Dichroism; DNA; Nucleic Acid Conformation; Putrescine; Spermidine; Spermine; Thermodynamics | 2013 |
Homeostasis of glutathione is associated with polyamine-mediated β-lactam susceptibility in Acinetobacter baumannii ATCC 19606.
Topics: Acinetobacter baumannii; Aztreonam; beta-Lactams; Biological Transport; Carbenicillin; DNA Transposable Elements; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Glutathione; Homeostasis; Membrane Transport Proteins; Mutagenesis; Oxidation-Reduction; Spermidine; Spermine | 2013 |
Polyamine levels in breast milk are associated with mothers' dietary intake and are higher in preterm than full-term human milk and formulas.
Topics: Adult; Arginine; Chromatography, High Pressure Liquid; Diet; Female; Humans; Infant Formula; Infant, Newborn; Lactation; Maternal Nutritional Physiological Phenomena; Methionine; Milk, Human; Premature Birth; Putrescine; Spermidine; Spermine; Sweden; Term Birth; Up-Regulation; Young Adult | 2014 |
Putrescine overproduction does not affect the catabolism of spermidine and spermine in poplar and Arabidopsis.
Topics: Arabidopsis; Cells, Cultured; Populus; Putrescine; Spermidine; Spermine | 2014 |
Effect of drought and combined drought and heat stress on polyamine metabolism in proline-over-producing tobacco plants.
Topics: Adaptation, Physiological; Arabidopsis Proteins; Droughts; Genes, Plant; Glutamate-5-Semialdehyde Dehydrogenase; Hot Temperature; Malondialdehyde; Multienzyme Complexes; Nicotiana; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Phosphotransferases (Alcohol Group Acceptor); Plant Leaves; Plant Proteins; Plant Roots; Polyamine Oxidase; Polyamines; Proline; Putrescine; Pyrroles; Spermidine; Spermine; Transformation, Genetic; Water | 2013 |
Oryza sativa polyamine oxidase 1 back-converts tetraamines, spermine and thermospermine, to spermidine.
Topics: Arabidopsis; Brassica; Hydrogen-Ion Concentration; Kinetics; Metabolic Networks and Pathways; Oryza; Oxidoreductases Acting on CH-NH Group Donors; Phylogeny; Plant Cells; Plant Roots; Polyamine Oxidase; Protein Transport; Recombinant Proteins; Sequence Homology, Amino Acid; Spermidine; Spermine; Subcellular Fractions; Transcription, Genetic | 2014 |
Effect of MeJA treatment on polyamine, energy status and anthracnose rot of loquat fruit.
Topics: Acetates; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Colletotrichum; Cyclopentanes; Disease Resistance; Eriobotrya; Food Microbiology; Fruit; Oxylipins; Plant Growth Regulators; Putrescine; Spermidine; Spermine | 2014 |
The relationship between polyamines and hormones in the regulation of wheat grain filling.
Topics: Edible Grain; Plant Growth Regulators; Plant Leaves; Plant Structures; Polyamines; Putrescine; Seeds; Spermidine; Spermine; Triticum | 2013 |
Resembling breast milk: influence of polyamine-supplemented formula on neonatal BALB/cOlaHsd mouse microbiota.
Topics: Animals; Animals, Newborn; Bacterial Load; Breast Feeding; Dietary Supplements; Food, Fortified; Gastrointestinal Tract; Humans; Infant Formula; Infant, Newborn; Mice; Mice, Inbred BALB C; Microbiota; Milk; Milk, Human; Polyamines; Putrescine; Spermidine; Spermine | 2014 |
Encapsulation of biogenic and synthetic polyamines by nanoparticles PEG and mPEG-anthracene.
Topics: Anthracenes; Drug Carriers; Hydrophobic and Hydrophilic Interactions; Nanoparticles; Polyethylene Glycols; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spermidine; Spermine | 2014 |
Spermidine alleviates the growth of saline-stressed ginseng seedlings through antioxidative defense system.
Topics: Amine Oxidase (Copper-Containing); Antioxidants; Dose-Response Relationship, Drug; Enzymes; Hydrogen Peroxide; Lipid Peroxidation; Oxidoreductases Acting on CH-NH Group Donors; Panax; Polyamine Oxidase; Polyamines; Proline; Salinity; Seedlings; Spermidine; Spermine; Stress, Physiological; Superoxides | 2014 |
Polyamine inhibitors for treatment of feline oral squamous cell carcinoma: a proof-of-concept study.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cat Diseases; Cats; Eflornithine; Evoked Potentials, Auditory, Brain Stem; Female; Hearing; Hearing Loss; Male; Mouth Mucosa; Mouth Neoplasms; Polyamines; Putrescine; Spermidine; Spermine; Thrombocytopenia | 2013 |
Micro extraction to quantitate spermidine and spermine in human urine and blood by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.
Topics: Humans; Indicators and Reagents; Liquid Phase Microextraction; Solvents; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spermidine; Spermine | 2014 |
Development of irreversible inactivators of spermine oxidase and N1-acetylpolyamine oxidase.
Topics: Enzyme Inhibitors; Humans; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Spermine | 2014 |
Functional characterization of the potRABCD operon for spermine and spermidine uptake and regulation in Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Drug Synergism; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Membrane Transport Proteins; Methicillin-Resistant Staphylococcus aureus; Operon; Polyamines; Promoter Regions, Genetic; Sequence Deletion; Spermidine; Spermine; Staphylococcal Infections; Transcriptome | 2014 |
Polyamine oxidase 7 is a terminal catabolism-type enzyme in Oryza sativa and is specifically expressed in anthers.
Topics: Aldehydes; Diamines; Flowers; Genes, Reporter; Hydrogen Peroxide; Kinetics; Organ Specificity; Oryza; Oxidoreductases Acting on CH-NH Group Donors; Peroxisomes; Phylogeny; Plant Epidermis; Plant Proteins; Plants, Genetically Modified; Polyamine Oxidase; Polyamines; Protein Sorting Signals; Putrescine; Spermidine; Spermine | 2014 |
Arginine decarboxylase and agmatinase: an alternative pathway for de novo biosynthesis of polyamines for development of mammalian conceptuses.
Topics: Agmatine; Animals; Carboxy-Lyases; Cationic Amino Acid Transporter 1; Citrulline; Embryo Implantation; Embryonic Development; Female; Mammals; Nitric Oxide Synthase Type III; Ornithine; Ornithine Decarboxylase; Pregnancy; Pregnancy, Animal; Putrescine; Sheep; Spermidine; Spermine; Ureohydrolases | 2014 |
Inhibition of polyamine formation antagonizes vascular smooth muscle cell proliferation and preserves the contractile phenotype.
Topics: Animals; Cattle; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Eflornithine; Inhibitory Concentration 50; Male; Muscle Contraction; Muscle, Smooth, Vascular; Ornithine Decarboxylase; Phenotype; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine | 2014 |
Biochemical defense strategies in sterilized seedlings of Nymphoides peltatum adapted to lead stress.
Topics: Adaptation, Physiological; Antioxidants; Ascorbic Acid; Glutathione; Lead; Magnoliopsida; Phytochelatins; Polyamines; Proline; Seedlings; Spermidine; Spermine; Sulfhydryl Compounds; Vitamin E; Water Pollutants, Chemical | 2014 |
In vivo investigation of homocysteine metabolism to polyamines by high-resolution accurate mass spectrometry and stable isotope labeling.
Topics: Animals; Homocysteine; Isotope Labeling; Molecular Structure; Rats; Rats, Wistar; Spermidine; Spermine | 2014 |
Spermidine, a sensor for antizyme 1 expression regulates intracellular polyamine homeostasis.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Line; Eflornithine; Homeostasis; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Proteins; Putrescine; Rats; Spermidine; Spermine | 2014 |
Changes of polyamine pattern in digestive glands of mussel Mytilus galloprovincialis under exposure to cadmium.
Topics: Animals; Bivalvia; Cadmium; Digestive System; Metallothionein; Mytilus; Oxidative Stress; Polyamines; Putrescine; Spermidine; Spermine | 2014 |
Polyamine modification by acrolein exclusively produces 1,5-diazacyclooctanes: a previously unrecognized mechanism for acrolein-mediated oxidative stress.
Topics: Acrolein; Amine Oxidase (Copper-Containing); Azocines; Cell Line, Tumor; Cell Survival; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Guanidines; HeLa Cells; Heme Oxygenase-1; Humans; Hydrogels; Oxidative Stress; Polymerization; Spermidine; Spermine | 2014 |
Electromembrane extraction of salivary polyamines followed by capillary zone electrophoresis with capacitively coupled contactless conductivity detection.
Topics: Cadaverine; Electric Conductivity; Electrochemical Techniques; Electrophoresis, Capillary; Humans; Membranes, Artificial; Mouth Diseases; Polyamines; Putrescine; Reproducibility of Results; Saliva; Sensitivity and Specificity; Solvents; Spermidine; Spermine; Toothbrushing | 2014 |
Comparison of the antibiotic activities of Daptomycin, Vancomycin, and the investigational Fluoroquinolone Delafloxacin against biofilms from Staphylococcus aureus clinical isolates.
Topics: Anti-Bacterial Agents; Biofilms; Daptomycin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Microbial Viability; Polyamines; Polysaccharides, Bacterial; Spermidine; Spermine; Staphylococcal Infections; Vancomycin | 2014 |
Natural product polyamines that inhibit human carbonic anhydrases.
Topics: Antineoplastic Agents; Biological Products; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cell Proliferation; Coumarins; Humans; Spermidine; Spermine; Structure-Activity Relationship | 2014 |
Targeting double-stranded RNA with spermine, 1-naphthylacetyl spermine and spermidine: a comparative biophysical investigation.
Topics: Calorimetry; Nucleic Acid Conformation; RNA, Double-Stranded; Spermidine; Spermine; Thermodynamics | 2014 |
Sensing conformational changes in DNA upon ligand binding using QCM-D. Polyamine condensation and Rad51 extension of DNA layers.
Topics: Biosensing Techniques; Cations; DNA; Models, Chemical; Models, Genetic; Nucleic Acid Conformation; Quartz Crystal Microbalance Techniques; Rad51 Recombinase; Spermidine; Spermine; Viscoelastic Substances; Viscosity; Water | 2014 |
Occurrence of polyamines in root nodules of Phaseolus vulgaris in symbiosis with Rhizobium tropici in response to salt stress.
Topics: Cadaverine; Fabaceae; Nitrogen Fixation; Phaseolus; Plant Leaves; Plant Roots; Polyamines; Polymerase Chain Reaction; Putrescine; Rhizobium tropici; Root Nodules, Plant; Salinity; Salt Tolerance; Sequence Homology, Nucleic Acid; Sodium Chloride; Spermidine; Spermine; Symbiosis | 2014 |
Polyamine depletion attenuates isoproterenol-induced hypertrophy and endoplasmic reticulum stress in cardiomyocytes.
Topics: Acetyltransferases; Animals; Apoptosis; Atrial Natriuretic Factor; bcl-2-Associated X Protein; Cardiomegaly; Caspase 12; Down-Regulation; Endoplasmic Reticulum Stress; HSP70 Heat-Shock Proteins; Isoproterenol; L-Lactate Dehydrogenase; Membrane Proteins; Myocytes, Cardiac; Ornithine Decarboxylase; Polyamines; Proto-Oncogene Proteins c-bcl-2; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Transcription Factor CHOP; Up-Regulation | 2014 |
Amine oxidase-based biosensors for spermine and spermidine determination.
Topics: Amine Oxidase (Copper-Containing); Biosensing Techniques; Enzymes, Immobilized; Humans; Limit of Detection; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Recombinant Proteins; Spermidine; Spermine; Substrate Specificity; Zea mays | 2015 |
Protective action of spermine and spermidine against photoinhibition of photosystem I in isolated thylakoid membranes.
Topics: Biological Transport; Dose-Response Relationship, Drug; Electron Transport; Light; Oxidation-Reduction; Oxygen; Photosystem I Protein Complex; Radiation-Protective Agents; Spermidine; Spermine; Spinacia oleracea; Superoxides; Thylakoids; Time Factors | 2014 |
Polyamine profile in ovine and caprine colostrum and milk.
Topics: Animals; Biogenic Polyamines; Chromatography, High Pressure Liquid; Colostrum; Female; Goats; Milk; Pregnancy; Putrescine; Sheep; Spermidine; Spermine | 2015 |
Biogenic amine – surfactant interactions at the air-water interface.
Topics: Adsorption; Putrescine; Sodium Dodecyl Sulfate; Spermidine; Spermine; Surface Tension; Surface-Active Agents; Water | 2015 |
Design, synthesis and in vitro antikinetoplastid evaluation of N-acylated putrescine, spermidine and spermine derivatives.
Topics: Acylation; Antiprotozoal Agents; Drug Design; Drug Evaluation, Preclinical; Kinetoplastida; Leishmania donovani; Putrescine; Spermidine; Spermine; Trypanosoma brucei brucei | 2015 |
Changes in the content of free and conjugated polyamines during Lettuce (Lactuca sativa) growth.
Topics: Lactuca; Polyamines; Putrescine; Spermidine; Spermine | 2015 |
Micro-scale strategy to detect spermine and spermidine by MALDI-TOF MS in foods and identification of apoptosis-related proteins by nano-flow UPLC-MS/MS after treatment with spermine and spermidine.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Chromatography, High Pressure Liquid; Food Analysis; Limit of Detection; Rats; Reproducibility of Results; Spermidine; Spermine; Tandem Mass Spectrometry | 2015 |
Brewing effect on levels of biogenic amines in different coffee samples as determined by LC-UV.
Topics: Biogenic Amines; Cadaverine; Chromatography, High Pressure Liquid; Coffea; Coffee; Dansyl Compounds; Food Handling; Histamine; Hot Temperature; Phenethylamines; Putrescine; Seeds; Serotonin; Spermidine; Spermine; Tyramine | 2015 |
A novel enzyme with spermine oxidase properties in bovine liver mitochondria: identification and kinetic characterization.
Topics: Animals; Catalytic Domain; Cattle; Hydrogen Peroxide; Kinetics; Liver; Mitochondria, Liver; Osmolar Concentration; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine; Spermine; Static Electricity; Substrate Specificity | 2015 |
The polyamine spermine promotes survival and activation of human eosinophils.
Topics: Apoptosis; Caspases; Cell Survival; Eosinophilia; Eosinophils; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Primary Cell Culture; Putrescine; Spermidine; Spermine | 2015 |
Pacific oyster polyamine oxidase: a protein missing link in invertebrate evolution.
Topics: Amino Acid Sequence; Animals; Catalytic Domain; Cloning, Molecular; Crassostrea; Escherichia coli; Gene Expression; Kinetics; Molecular Docking Simulation; Molecular Sequence Data; Oxidoreductases Acting on CH-NH Group Donors; Phylogeny; Polyamine Oxidase; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Spermidine; Spermine; Substrate Specificity | 2015 |
Influence of ornithine decarboxylase antizymes and antizyme inhibitors on agmatine uptake by mammalian cells.
Topics: Agmatine; Animals; Biological Transport; Carboxy-Lyases; Carrier Proteins; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Furans; Genetic Vectors; Guanidine; Humans; Hydrogen-Ion Concentration; Kinetics; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine; Transfection | 2015 |
Depletion of the polyamines spermidine and spermine by overexpression of spermidine/spermine N¹-acetyltransferase 1 (SAT1) leads to mitochondria-mediated apoptosis in mammalian cells.
Topics: Acetyltransferases; Antimetabolites; Apoptosis; Apoptosis Regulatory Proteins; Cell Proliferation; Cell Shape; Cell Size; HEK293 Cells; Humans; In Situ Nick-End Labeling; Kidney; Kinetics; Membrane Potential, Mitochondrial; Microscopy, Electron, Transmission; Mitochondria; Recombinant Proteins; Spermidine; Spermine | 2015 |
Application of γ-aminobutyric acid demonstrates a protective role of polyamine and GABA metabolism in muskmelon seedlings under Ca(NO3)2 stress.
Topics: 4-Aminobutyrate Transaminase; Adaptation, Physiological; Adenosylmethionine Decarboxylase; Amine Oxidase (Copper-Containing); Calcium Compounds; Cucumis; gamma-Aminobutyric Acid; Nitrates; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Plant Leaves; Plant Proteins; Plant Roots; Polyamine Oxidase; Polyamines; Putrescine; Seedlings; Spermidine; Spermine; Stress, Physiological | 2015 |
Impaired osteoblast and osteoclast function characterize the osteoporosis of Snyder - Robinson syndrome.
Topics: Fibroblasts; Humans; Male; Mental Retardation, X-Linked; Mesenchymal Stem Cells; Mutation; Osteoblasts; Osteoclasts; Osteoporosis; Spermidine; Spermine; Spermine Synthase | 2015 |
Macrocyclic naphthalene diimides as G-quadruplex binders.
Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Survival; DNA, Neoplasm; Drug Design; G-Quadruplexes; Humans; Imides; Molecular Docking Simulation; Molecular Dynamics Simulation; Naphthalenes; Spermidine; Spermine; Static Electricity; Structure-Activity Relationship | 2015 |
Modulation of cadmium toxicity and enhancing cadmium-tolerance in wheat seedlings by exogenous application of polyamines.
Topics: Antioxidants; Ascorbic Acid; Cadmium; Catalase; Glutathione; Hydrogen Peroxide; Malondialdehyde; Oxidative Stress; Peroxidases; Plant Leaves; Seedlings; Seeds; Spermidine; Spermine; Superoxide Dismutase; Triticum | 2015 |
Sulfur amino acid metabolism in Zucker diabetic fatty rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Animals; Area Under Curve; Betaine; Betaine-Homocysteine S-Methyltransferase; Cysteine; Dipeptides; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Homocysteine; Liver; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Rats; Rats, Zucker; S-Adenosylhomocysteine; S-Adenosylmethionine; Spermidine; Spermine; Taurine | 2015 |
Metabolomic analyses reveal that anti-aging metabolites are depleted by palmitate but increased by oleate in vivo.
Topics: Aging; Amino Acids; Animals; Autophagy; Female; Liver; Mass Spectrometry; Metabolomics; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Myocardium; NAD; Oleic Acid; Palmitates; Phosphatidylinositol 3-Kinases; Principal Component Analysis; Signal Transduction; Spermidine; Spermine | 2015 |
Suppression of ornithine decarboxylase promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells.
Topics: Adipogenesis; Bone Marrow Cells; Bone Matrix; Calcification, Physiologic; Cell Proliferation; Cells, Cultured; Eflornithine; Gene Expression Regulation, Developmental; Humans; Kinetics; Lipid Metabolism; Mesenchymal Stem Cells; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Osteogenesis; Putrescine; RNA Interference; RNA, Small Interfering; Spermidine; Spermine | 2015 |
Characterization of a spermine/spermidine transport system reveals a novel DNA sequence duplication in Neisseria gonorrhoeae.
Topics: Amino Acid Sequence; Base Sequence; Biological Transport; Computational Biology; Culture Media; Gene Duplication; Membrane Transport Proteins; Molecular Sequence Data; Mutation; Neisseria gonorrhoeae; Operon; Spermidine; Spermine | 2015 |
Free and Cell Wall-Bound Polyamines under Long-Term Water Stress Applied at Different Growth Stages of ×Triticosecale Wittm.
Topics: Agmatine; Cadaverine; Cell Wall; Chromatography, High Pressure Liquid; Desiccation; Droughts; Plant Cells; Putrescine; Spermidine; Spermine; Stress, Physiological; Triticale; Water | 2015 |
Targeting polyamine biosynthetic pathway through RNAi causes the abrogation of MCF 7 breast cancer cell line.
Topics: Adenosylmethionine Decarboxylase; Apoptosis; Breast Neoplasms; Cell Differentiation; Cell Division; Cell Movement; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Ornithine Decarboxylase; Polyamines; Putrescine; RNA Interference; RNA, Messenger; RNA, Small Interfering; Spermidine; Spermidine Synthase; Spermine | 2016 |
Lead-stress induced changes in the content of free, thylakoid- and chromatin-bound polyamines, photosynthetic parameters and ultrastructure in greening barley leaves.
Topics: Chlorophyll; Chromatin; Hordeum; Hydrogen Peroxide; Lead; Malondialdehyde; Photosynthesis; Plant Leaves; Polyamines; Putrescine; Spermidine; Spermine; Stress, Physiological; Thylakoids | 2015 |
The polyamine oxidase from lycophyte Selaginella lepidophylla (SelPAO5), unlike that of angiosperms, back-converts thermospermine to norspermidine.
Topics: Chromatography, High Pressure Liquid; Dehydration; Gene Expression Regulation, Plant; Molecular Structure; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Phylogeny; Plant Proteins; Polyamine Oxidase; Reverse Transcriptase Polymerase Chain Reaction; Selaginellaceae; Spectrophotometry; Spermidine; Spermine; Tandem Mass Spectrometry; Water | 2015 |
Identification and biochemical characterization of polyamine oxidases in amphioxus: Implications for emergence of vertebrate-specific spermine and acetylpolyamine oxidases.
Topics: Animals; Catalytic Domain; Cloning, Molecular; Evolution, Molecular; Lancelets; Models, Molecular; Organ Specificity; Oxidoreductases Acting on CH-NH Group Donors; Protein Structure, Tertiary; Spermidine; Spermine; Structure-Activity Relationship; Substrate Specificity | 2016 |
Spatiotemporal patterning of polyamines in Drosophila development.
Topics: Animals; Body Patterning; Computational Biology; Drosophila melanogaster; Gene Expression Profiling; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Immunohistochemistry; Photoreceptor Cells, Invertebrate; Polyamines; Spermidine; Spermine; Time Factors; Trachea; Transcription, Genetic | 2015 |
Putrescine induces somatic embryo development and proteomic changes in embryogenic callus of sugarcane.
Topics: Computational Biology; Culture Media; Glutathione Transferase; Mucoproteins; Plant Proteins; Plant Somatic Embryogenesis Techniques; Polyamines; Proteome; Proteomics; Putrescine; Saccharum; Spectrometry, Mass, Electrospray Ionization; Spermidine; Spermine; Tandem Mass Spectrometry | 2016 |
Identification and Characterization of Kukoamine Metabolites by Multiple Ion Monitoring Triggered Enhanced Product Ion Scan Method with a Triple-Quadruple Linear Ion Trap Mass Spectrometer.
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Mass Spectrometry; Molecular Structure; Polyamines; Spermidine; Spermine | 2015 |
Phloem-Specific Methionine Recycling Fuels Polyamine Biosynthesis in a Sulfur-Dependent Manner and Promotes Flower and Seed Development.
Topics: Aldose-Ketose Isomerases; Arabidopsis; Arabidopsis Proteins; Deoxyadenosines; Ethylenes; Flowers; Methionine; Mutation; Organ Specificity; Phloem; Plant Growth Regulators; Polyamines; Putrescine; Seeds; Spermidine; Spermine; Sulfur; Thioglycosides; Thionucleosides | 2016 |
Decreased sensitivity to aspirin is associated with altered polyamine metabolism in human prostate cancer cells.
Topics: Acetyltransferases; Anticarcinogenic Agents; Aspirin; Cell Line, Tumor; Drug Resistance, Neoplasm; Epithelial Cells; Gene Expression Regulation; Humans; Male; Prostate; Putrescine; Spermidine; Spermine | 2016 |
Thermodynamic analysis of biogenic and synthetic polyamines conjugation with PAMAM-G4 nanoparticles.
Topics: Biogenic Polyamines; Dendrimers; Hydrogen Bonding; Nanoparticles; Nylons; Polyamines; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spermidine; Spermine; Static Electricity; Thermodynamics | 2016 |
Increased uptake of oxidized LDL by macrophages from type 2 diabetics is inhibited by polyamines.
Topics: alpha-Tocopherol; Antioxidants; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Lipid Peroxidation; Lipids; Lipoproteins, LDL; Macrophages; Male; Middle Aged; Polyamines; Putrescine; Spermidine; Spermine | 2016 |
Effect of polyamines on the grain filling of wheat under drought stress.
Topics: Plant Growth Regulators; Seeds; Spermidine; Spermine; Stress, Physiological; Triticum | 2016 |
A Trans-omics Mathematical Analysis Reveals Novel Functions of the Ornithine Metabolic Pathway in Cancer Stem Cells.
Topics: Acetyltransferases; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cisplatin; Computational Biology; Drug Resistance, Neoplasm; Esophagus; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Metabolic Networks and Pathways; Metabolome; Models, Statistical; Neoplastic Stem Cells; Ornithine; Proteins; Putrescine; Spermidine; Spermine; Spermine Synthase; Transcriptome | 2016 |
Chemical control of xylem differentiation by thermospermine, xylemin, and auxin.
Topics: 2,4-Dichlorophenoxyacetic Acid; Arabidopsis; Arabidopsis Proteins; Cell Differentiation; Indoleacetic Acids; Putrescine; Spermidine; Spermine; Xylem | 2016 |
'Smelling' the cerebrospinal fluid: olfactory signaling molecules are expressed in and mediate chemosensory signaling from the choroid plexus.
Topics: Adenylyl Cyclases; Animals; Cadaverine; Cell Line; Choroid Plexus; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Epithelial Cells; Gene Expression Regulation; GTP-Binding Protein alpha Subunits; Inositol 1,4,5-Trisphosphate; Olfactory Pathways; Olfactory Perception; Polyamines; Primary Cell Culture; Putrescine; Rats; Rats, Wistar; RNA, Small Interfering; Signal Transduction; Spermidine; Spermine; Type C Phospholipases | 2016 |
T-2307, a novel arylamidine, is transported into Candida albicans by a high-affinity spermine and spermidine carrier regulated by Agp2.
Topics: Amidines; Antifungal Agents; Biological Transport; Candida albicans; Carbon Radioisotopes; Carrier Proteins; Gene Deletion; Isotope Labeling; Kinetics; Microbial Sensitivity Tests; Polymerase Chain Reaction; Spermidine; Spermine | 2016 |
Oral administration of polyamines ameliorates liver ischemia/reperfusion injury and promotes liver regeneration in rats.
Topics: Administration, Oral; Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Cell Proliferation; Disease Models, Animal; Ki-67 Antigen; Liver; Liver Regeneration; Liver Transplantation; Male; Necrosis; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred Lew; Reperfusion Injury; Retinoblastoma Protein; Spermidine; Spermine | 2016 |
Genetic manipulation of putrescine biosynthesis reprograms the cellular transcriptome and the metabolome.
Topics: Gas Chromatography-Mass Spectrometry; Metabolome; Ornithine Decarboxylase; Polyamines; Populus; Putrescine; Spermidine; Spermine; Transcriptome | 2016 |
The effect of pH on charge inversion and condensation of DNA.
Topics: Cobalt; DNA; Electrophoresis; Hydrogen-Ion Concentration; Spermidine; Spermine | 2016 |
Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses.
Topics: Acetyltransferases; Chikungunya virus; Polyamines; Spermidine; Spermine; Virus Replication; Zika Virus | 2016 |
DNA-HMGB1 interaction: The nuclear aggregates of polyamine mediation.
Topics: Cell Nucleus; DNA; Genome; HMGB1 Protein; Humans; Microscopy, Atomic Force; Nucleic Acid Conformation; Polyamines; Protein Aggregates; Spermidine; Spermine | 2016 |
Microwave assisted synthesis of tyrosine protected gold nanoparticles for dual (colorimetric and fluorimetric) detection of spermine and spermidine in biological samples.
Topics: Biosensing Techniques; Colorimetry; Gold; Humans; Limit of Detection; Metal Nanoparticles; Microwaves; Nanotechnology; Spectrometry, Fluorescence; Spermidine; Spermine; Tyrosine | 2017 |
Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers.
Topics: Aged; Aged, 80 and over; Area Under Curve; Biomarkers, Tumor; Biopsy; Case-Control Studies; Chromatography, High Pressure Liquid; Diagnosis, Differential; Humans; Male; Middle Aged; Neoplasm Grading; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Putrescine; Spermidine; Spermine; Ultrasound, High-Intensity Focused, Transrectal | 2016 |
RNA-Based Coacervates as a Model for Membraneless Organelles: Formation, Properties, and Interfacial Liposome Assembly.
Topics: Amino Acid Sequence; Artificial Cells; Fluorescence Recovery After Photobleaching; Glycerophospholipids; Nucleic Acid Conformation; Oligoribonucleotides; Peptides; Phase Transition; RNA; Spermidine; Spermine; Transition Temperature; Unilamellar Liposomes | 2016 |
Insights into the Biogenic Amine Metabolic Landscape during Industrial Semidry Chinese Rice Wine Fermentation.
Topics: Acids; Arginine; Biogenic Amines; Chromatography, High Pressure Liquid; Ethanol; Fermentation; Lactic Acid; Lactobacillus; Ornithine; Oryza; Putrescine; Spermidine; Spermine; Wine | 2016 |
Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses.
Topics: Acetyltransferases; Animals; Apoptosis; Arachidonate 15-Lipoxygenase; Carcinogenesis; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; CRISPR-Cas Systems; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Lipid Peroxidation; Metabolic Networks and Pathways; Mice; Neoplasm Proteins; Neoplasms; Oxidative Stress; Polyamines; Proto-Oncogene Proteins c-mdm2; Reactive Oxygen Species; Spermidine; Spermine; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Xenograft Model Antitumor Assays | 2016 |
Magnesium chloride and polyamine can differentiate mouse embryonic stem cells into trophectoderm or endoderm.
Topics: Animals; Cations; Cell Differentiation; Cell Nucleus; Chromatin; Dose-Response Relationship, Drug; Endoderm; Magnesium Chloride; Mice; Mouse Embryonic Stem Cells; Polyamines; Spermidine; Spermine | 2017 |
The Structure of Murine N
Topics: Aldehydes; Animals; Catalytic Domain; Gene Expression; Hydrogen Peroxide; Kinetics; Mice; Models, Molecular; Oxidation-Reduction; Oxidoreductases; Propylamines; Protein Structure, Secondary; Putrescine; Spermidine; Spermine | 2017 |
Hepatitis C virus alters metabolism of biogenic polyamines by affecting expression of key enzymes of their metabolism.
Topics: Acetyltransferases; Biogenic Polyamines; Cell Line; Gene Expression Regulation, Enzymologic; Hepacivirus; Host-Pathogen Interactions; Humans; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Spermine; Viral Core Proteins; Viral Nonstructural Proteins; Virus Replication | 2017 |
Vesicular Polyamine Transporter Mediates Vesicular Storage and Release of Polyamine from Mast Cells.
Topics: Animals; Calcimycin; Calcium; Cathepsin D; Cation Transport Proteins; Exocytosis; Histamine; Histamine Release; Immunohistochemistry; Male; Mast Cells; Mice; Microscopy, Fluorescence; Polyamines; R-SNARE Proteins; Rats; Rats, Wistar; Secretory Vesicles; Serotonin; Spermidine; Spermine; Vesicle-Associated Membrane Protein 2; Vesicle-Associated Membrane Protein 3; Vesicular Monoamine Transport Proteins | 2017 |
Comparative analysis of polyamine metabolism in wheat and maize plants.
Topics: Biomass; Chlorophyll; Chlorophyll A; Fluorescence; Gases; Lipid Peroxidation; Models, Biological; Osmotic Pressure; Phenylalanine Ammonia-Lyase; Plant Leaves; Polyamines; Polyethylene Glycols; Proline; Putrescine; Salicylic Acid; Spermidine; Spermine; Triticum; Zea mays | 2017 |
[POLYAMINE CONCENTRATION IN ERYTHROCYTES IN THE BLOOD OF PREGNANT WOMEN WITH INTRAUTERINE GROWTH RETARDATION].
Topics: Adult; Case-Control Studies; Erythrocytes; Female; Fetal Growth Retardation; Humans; Polyamines; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Putrescine; Spermidine; Spermine; Young Adult | 2016 |
Bioamine-crosslinked gellan gum hydrogel for neural tissue engineering.
Topics: Animals; Biocompatible Materials; Biomechanical Phenomena; Biomimetic Materials; Cell Differentiation; Cross-Linking Reagents; Humans; Hydrogels; Induced Pluripotent Stem Cells; Laminin; Male; Materials Testing; Nerve Tissue; Neural Stem Cells; Neurites; Polysaccharides, Bacterial; Rabbits; Rheology; Spermidine; Spermine; Tissue Engineering | 2017 |
Expression of ODC1, SPD, SPM and AZIN1 in the hypothalamus, ovary and uterus during rat estrous cycle.
Topics: Animals; Enzyme Inhibitors; Estrous Cycle; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Image Processing, Computer-Assisted; Immunoenzyme Techniques; Ornithine Decarboxylase; Ovary; Polyamines; Progesterone; Protein Precursors; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Uterus | 2017 |
Sensitivity to Enterocins of Biogenic Amine-Producing Faecal Enterococci from Ostriches and Pheasants.
Topics: Animals; Biogenic Amines; Bridged-Ring Compounds; Enterococcus; Feces; Galliformes; Phenethylamines; Spermidine; Spermine; Struthioniformes; Tyramine | 2017 |
Screening of Some Dioxaboreninopyridine and Aniline Derivatives for Carcinogenic Properties Using a Model Cell-Free System of Regenerating Rat Liver.
Topics: Amine Oxidase (Copper-Containing); Aniline Compounds; Animals; Antineoplastic Agents; Boron Compounds; Carcinogens; Cell-Free System; Enzyme Assays; Kinetics; Liver; Liver Regeneration; Male; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Pyridines; Rats; Spermidine; Spermine; Structure-Activity Relationship | 2017 |
Polyamine-RNA-membrane interactions: From the past to the future in biology.
Topics: Drug Carriers; Fatty Alcohols; Kinetics; Models, Chemical; Oleic Acid; Origin of Life; Phosphatidylcholines; Phosphatidylinositol Phosphates; Phosphatidylinositols; Putrescine; RNA, Transfer; Saccharomyces cerevisiae; Spermidine; Spermine; Static Electricity; Thermodynamics; Unilamellar Liposomes | 2017 |
Polyamines contribute to salinity tolerance in the symbiosis Medicago truncatula-Sinorhizobium meliloti by preventing oxidative damage.
Topics: Brassinosteroids; Medicago truncatula; Polyamines; Sinorhizobium meliloti; Sodium Chloride; Spermidine; Spermine; Symbiosis | 2017 |
Histone deacetylase 10 structure and molecular function as a polyamine deacetylase.
Topics: Amino Acid Sequence; Animals; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Gene Expression; Histone Deacetylases; Humans; Isoenzymes; Kinetics; Models, Molecular; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Spermidine; Spermine; Substrate Specificity; Zebrafish; Zebrafish Proteins | 2017 |
Biogenic amine concentrations and evolution in "chilled" Canadian pork for the Japanese market.
Topics: Animals; Biogenic Amines; Cadaverine; Canada; Putrescine; Red Meat; Spermidine; Spermine; Swine | 2017 |
Molecular Dynamics Insights into Polyamine-DNA Binding Modes: Implications for Cross-Link Selectivity.
Topics: Binding Sites; DNA; Molecular Dynamics Simulation; Nucleic Acid Conformation; Polyamines; Putrescine; Spermidine; Spermine; Thermodynamics | 2017 |
Spermine and spermidine act as chemical chaperones and enhance chaperone-like and membranolytic activities of major bovine seminal plasma protein, PDC-109.
Topics: Animals; Cattle; Cell Membrane; Erythrocyte Membrane; Fructose-Bisphosphate Aldolase; Hot Temperature; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Membrane Lipids; Membranes, Artificial; Molecular Chaperones; Oxidative Stress; Protein Aggregates; Protein Denaturation; Semen; Seminal Vesicle Secretory Proteins; Spermidine; Spermine; Stress, Physiological | 2017 |
Development of Amine-Oxidase-Based Biosensors for Spermine and Spermidine Analysis.
Topics: Biogenic Amines; Biosensing Techniques; Electrodes; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Spermine | 2018 |
Determination of S-Adenosylmethionine Decarboxylase Activity in Plants.
Topics: Adenosylmethionine Decarboxylase; Enzyme Activation; Enzyme Assays; Plant Extracts; Plants; Spermidine; Spermine | 2018 |
Expression and distribution patterns of spermine, spermidine, and putrescine in rat hair follicle.
Topics: Animals; Antibodies, Monoclonal; Hair Follicle; Putrescine; Rats; Spermidine; Spermine | 2018 |
Polyamines regulating phytic acid degradation in mung bean sprouts.
Topics: Cyclohexylamines; Energy Metabolism; Germination; Phytic Acid; Plant Growth Regulators; Polyamines; Putrescine; Seedlings; Seeds; Spermidine; Spermine; Vigna | 2018 |
Biophysical characterization of the DNA interaction with the biogenic polyamine putrescine: A single molecule study.
Topics: Binding Sites; Biogenic Polyamines; Biophysical Phenomena; DNA; DNA-Binding Proteins; Models, Molecular; Nanotechnology; Nucleic Acid Conformation; Osmolar Concentration; Spermidine; Spermine | 2018 |
Competitive fluorescent pseudo-immunoassay exploiting molecularly imprinted polymers for the detection of biogenic amines in fish matrix.
Topics: Animals; Biogenic Amines; Fishes; Fluoroimmunoassay; Molecular Imprinting; Polymers; Reproducibility of Results; Seafood; Spermidine; Spermine; Tryptamines; Tyramine | 2018 |
Functional characterization of murB-potABCD operon for polyamine uptake and peptidoglycan synthesis in Streptococcus suis.
Topics: Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Biological Transport; Gene Deletion; Gene Knockout Techniques; Humans; Operon; Peptidoglycan; Polyamines; Putrescine; Spermidine; Spermine; Streptococcus suis; Swine | 2018 |
Opposite effect of polyamines on In vitro gene expression: Enhancement at low concentrations but inhibition at high concentrations.
Topics: DNA; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation; In Vitro Techniques; Microscopy, Atomic Force; Models, Molecular; Nucleic Acid Conformation; Polyamines; Spermidine; Spermine; Up-Regulation | 2018 |
Determination of Biogenic Amines in Cheese by Ion Chromatography with Tandem Mass Spectrometry Detection.
Topics: Biogenic Amines; Cadaverine; Cheese; Chromatography, Ion Exchange; Food Analysis; Limit of Detection; Methylamines; Spermidine; Spermine; Tandem Mass Spectrometry; Tyramine | 2018 |
Immunological blocking of spermidine-mediated host-pathogen communication provides effective control against Pseudomonas aeruginosa infection.
Topics: Animals; Communication; Mice; Pseudomonas aeruginosa; Pseudomonas Infections; Spermidine; Spermine | 2020 |
Analysis of polyamine biosynthetic- and transport ability of human indigenous Bifidobacterium.
Topics: Anaerobiosis; Bifidobacterium; Biological Transport; Chromatography, High Pressure Liquid; Culture Media; Humans; Membrane Transport Proteins; Putrescine; Species Specificity; Spermidine; Spermine | 2018 |
Progesterone-associated arginine decline at luteal phase of menstrual cycle and associations with related amino acids and nuclear factor kB activation.
Topics: Adult; Amino Acids; Arginine; Citrulline; Female; Follicular Phase; Healthy Volunteers; Humans; Leukocytes, Mononuclear; Luteal Phase; NF-kappa B p50 Subunit; Ornithine; Progesterone; Putrescine; Reference Values; Spermidine; Spermine; Transcription Factor RelA | 2018 |
Oxidative degradation of polyamines by serum supplement causes cytotoxicity on cultured cells.
Topics: Acrolein; Animals; Cell Culture Techniques; Cell Line, Tumor; Cells, Cultured; Drug Resistance; Humans; Hydrogen Peroxide; Oxidation-Reduction; Polyamines; Serum; Spermidine; Spermine | 2018 |
Spermine and spermidine are cytotoxic towards intestinal cell cultures, but are they a health hazard at concentrations found in foods?
Topics: Cells, Cultured; Dose-Response Relationship, Drug; Food Analysis; Humans; Intestines; Polyamines; Putrescine; Spermidine; Spermine | 2018 |
Identification of essential yeast genes involved in polyamine resistance.
Topics: Drug Resistance, Fungal; Gene Expression Regulation, Fungal; Genes, Essential; Leucine; Mutation; Polyamines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spermidine; Spermine; Transcription Factors | 2018 |
A Metabolomics Profiling of Glaucoma Points to Mitochondrial Dysfunction, Senescence, and Polyamines Deficiency.
Topics: Aged; Aging; Eye Proteins; Female; Glaucoma, Open-Angle; Humans; Male; Mass Spectrometry; Metabolome; Metabolomics; Mitochondrial Diseases; Principal Component Analysis; Spermidine; Spermine | 2018 |
Polyamine-independent growth and biofilm formation, and functional spermidine/spermine N-acetyltransferases in Staphylococcus aureus and Enterococcus faecalis.
Topics: Acetylation; Acetyltransferases; Biofilms; Enterococcus faecalis; Protein Processing, Post-Translational; Spermidine; Spermine; Staphylococcus aureus | 2019 |
Modulation of plant and bacterial polyamine metabolism during the compatible interaction between tomato and Pseudomonas syringae.
Topics: Chlorophyll A; Gene Expression Profiling; Host-Pathogen Interactions; Plant Diseases; Plant Immunity; Plant Leaves; Pseudomonas syringae; Putrescine; Solanum lycopersicum; Spermidine; Spermine | 2018 |
Silicon enhances the salt tolerance of cucumber through increasing polyamine accumulation and decreasing oxidative damage.
Topics: Chlorophyll; Cucumis sativus; Oxidative Stress; Plant Leaves; Plant Roots; Polyamines; Putrescine; Salt Tolerance; Salt-Tolerant Plants; Silicon; Spermidine; Spermine | 2019 |
Microbial diversity and chemical analysis of Shuidouchi, traditional Chinese fermented soybean.
Topics: Bacteria; Biodiversity; Biogenic Amines; Cadaverine; China; Chromatography, High Pressure Liquid; Colony Count, Microbial; Fermentation; Fermented Foods; Food Microbiology; Fungi; Glycine max; Histamine; Phenethylamines; Putrescine; RNA, Ribosomal, 16S; Spermidine; Spermine; Tryptamines; Tyramine | 2019 |
Serum polyamine metabolic profile in autoimmune thyroid disease patients.
Topics: Adult; Autoantibodies; Disease Progression; Female; Graves Disease; Hashimoto Disease; Humans; Hypothyroidism; Male; Middle Aged; Spermidine; Spermine | 2019 |
Role of polyamines in plant growth regulation of Rht wheat mutants.
Topics: Abscisic Acid; Antioxidants; Enzymes; Gene Expression Regulation, Plant; Indoleacetic Acids; Lipid Peroxidation; Mutation; Plant Growth Regulators; Plant Leaves; Plant Roots; Polyamines; Proline; Putrescine; Salicylic Acid; Spermidine; Spermine; Triticum | 2019 |
Polyamines levels increase in smut teliospores after contact with sugarcane glycoproteins as a plant defensive mechanism.
Topics: Biogenic Polyamines; Glycoproteins; Plant Diseases; Plant Immunity; Putrescine; Saccharum; Spermidine; Spermine; Spores, Fungal; Ustilaginales | 2019 |
Extracellular Spermine Activates DNA Methyltransferase 3A and 3B.
Topics: Adenosylmethionine Decarboxylase; Cell Line, Tumor; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Modification Methylases; Eflornithine; Epithelial Cells; Humans; Jurkat Cells; Mammary Glands, Human; Ornithine Decarboxylase; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine | 2019 |
Oral administration of l-ornithine increases the content of both collagen constituting amino acids and polyamines in mouse skin.
Topics: Administration, Oral; Amino Acids; Animals; Collagen; Male; Mice, Inbred ICR; Ornithine; Polyamines; Putrescine; Skin; Spermidine; Spermine | 2019 |
Myosin Va and spermine synthase: partners in exosome transport.
Topics: Animals; Exosomes; Humans; Mental Retardation, X-Linked; Spermidine; Spermine; Spermine Synthase | 2019 |
Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Humans; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Oxidoreductases Acting on CH-NH Group Donors; Plant Proteins; Polyamine Oxidase; Spermidine; Spermine; Time Factors; Zea mays | 2019 |
Pattern preferences of DNA nucleotide motifs by polyamines putrescine2+, spermidine3+ and spermine4.
Topics: Deoxyribonucleotides; DNA; Molecular Dynamics Simulation; Nucleic Acid Conformation; Nucleotide Motifs; Putrescine; Spermidine; Spermine; Static Electricity | 2019 |
Involvement of polyamines in sucrose-induced tolerance to atrazine-mediated chemical stress in Arabidopsis thaliana.
Topics: Arabidopsis; Atrazine; Cell Death; Herbicide Resistance; Herbicides; Oxidative Stress; Photosynthesis; Photosystem II Protein Complex; Putrescine; Real-Time Polymerase Chain Reaction; Seedlings; Spermidine; Spermine; Sucrose; Transcriptome | 2019 |
Polyamines modulate growth, antioxidant activity, and genomic DNA in heavy metal-stressed wheat plant.
Topics: Antioxidants; Ascorbic Acid; Cadmium; DNA; Genomics; Glutathione Reductase; Inactivation, Metabolic; Oxidation-Reduction; Oxidoreductases; Peroxidases; Plant Leaves; Polyamines; Seedlings; Seeds; Spermidine; Spermine; Superoxide Dismutase; Triticum | 2019 |
New coordination compounds of citric acid and polyamines with lanthanide ions - potential application in monitoring the treatment of cancer diseases.
Topics: Citric Acid; Coordination Complexes; Hydrogen-Ion Concentration; Lanthanoid Series Elements; Luminescence; Luminescent Agents; Luminescent Measurements; Polyamines; Putrescine; Spermidine; Spermine | 2019 |
Removal of biogenic amines from hydroalcoholic solutions by functionalized silica.
Topics: Adsorption; Amines; Biogenic Amines; Cadaverine; Chromatography, High Pressure Liquid; Gels; Histamine; Mass Spectrometry; Porosity; Putrescine; Silicon Dioxide; Spermidine; Spermine; Sulfonic Acids; Surface Properties; Tyramine | 2019 |
Bioactive amines changes during the ripening and thermal processes of bananas and plantains.
Topics: Amines; Biogenic Amines; Dopamine; Fruit; Genotype; Histamine; Musa; Plantago; Putrescine; Serotonin; Spermidine; Spermine; Temperature; Tyramine | 2019 |
Polyamines alleviate the inhibitory effect of the DNA cross-linking agent mitomycin C on root growth.
Topics: Arabidopsis; Cross-Linking Reagents; DNA Damage; Gene Expression Regulation, Plant; Mitomycin; Plant Roots; Polyamines; Putrescine; Spermidine; Spermine | 2019 |
Effect of exogenous spermidine on floral induction, endogenous polyamine and hormone production, and expression of related genes in 'Fuji' apple (Malus domestica Borkh.).
Topics: Abscisic Acid; Flowers; Gibberellins; Malus; Putrescine; Spermidine; Spermine | 2019 |
Polyamine supplementation reduces DNA damage in adipose stem cells cultured in 3-D.
Topics: Adult; Aged; Cells, Cultured; DNA Damage; Histones; Humans; Mesenchymal Stem Cells; Middle Aged; Spermidine; Spermine | 2019 |
Spermine ameliorates prolonged fluoride toxicity in soil-grown rice seedlings by activating the antioxidant machinery and glyoxalase system.
Topics: Antioxidants; Catalase; Fluorides; Glutathione Peroxidase; Hydrogen Peroxide; Lactoylglutathione Lyase; Malondialdehyde; Oryza; Oxidation-Reduction; Oxidative Stress; Peroxidase; Reactive Oxygen Species; Seedlings; Soil; Soil Pollutants; Spermidine; Spermine; Superoxide Dismutase | 2020 |
Gender-Related Differences on Polyamine Metabolome in Liquid Biopsies by a Simple and Sensitive Two-Step Liquid-Liquid Extraction and LC-MS/MS.
Topics: Acetylation; Cadaverine; Chromatography, Liquid; Dansyl Compounds; Diamines; Female; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Liquid Biopsy; Liquid-Liquid Extraction; Male; Metabolome; Obesity; Polyamines; Putrescine; Sex Characteristics; Spermidine; Spermine; Tandem Mass Spectrometry | 2019 |
Polyamine acetylation and substrate-induced oligomeric states in histone acetyltransferase of multiple drug resistant Acinetobacter baumannii.
Topics: Acetylation; Acinetobacter baumannii; Biofilms; Drug Resistance, Multiple, Bacterial; Escherichia coli; Histone Acetyltransferases; Kanamycin; Polyamines; Protein Multimerization; Spermidine; Spermine | 2020 |
Intervening in sibling competition for assimilates by controlled pollination prevents seed abortion under postpollination drought in maize.
Topics: Carbohydrates; Dehydration; Edible Grain; Ethylenes; Photosynthesis; Plant Leaves; Pollination; Putrescine; Spermidine; Spermine; Water; Zea mays | 2020 |
Detection of polyamines using immunobiosensor based on zinc oxide nanoparticles.
Topics: Antibodies, Immobilized; Biosensing Techniques; Humans; MCF-7 Cells; Nanoparticles; Polyamines; Spermidine; Spermine; Zinc Oxide | 2019 |
Differences of endogenous polyamines and putative genes associated with paraquat resistance in goosegrass (Eleusine indica L.).
Topics: Drug Resistance; Eleusine; Gene Expression Regulation, Plant; Herbicides; Paraquat; Polyamines; Putrescine; Spermidine; Spermine | 2019 |
Regulation of the biosynthesis of endogenous nitric oxide and abscisic acid in stored peaches by exogenous nitric oxide and abscisic acid.
Topics: Abscisic Acid; Adenosylmethionine Decarboxylase; Aldehyde Oxidase; Arginine; Carboxy-Lyases; Dioxygenases; Food Storage; Fruit; Gene Expression Regulation, Plant; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidoreductases; Plant Proteins; Prunus persica; Spermidine; Spermine | 2020 |
Role of genes and metabolites involved in polyamines synthesis pathways and nitric oxide synthase in stomatal closure on Rosa damascena Mill. under drought stress.
Topics: Droughts; Gene Expression Regulation, Plant; Hydrogen Peroxide; Nitric Oxide Synthase; Plant Stomata; Polyamines; Rosa; Spermidine; Spermine; Stress, Physiological | 2020 |
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Topics: Acetyltransferases; Animals; Brain; Chromatography, High Pressure Liquid; Fibroblasts; Humans; Male; Mental Retardation, X-Linked; Mice; Mice, Inbred C57BL; Polyamines; Spermidine; Spermine; Spermine Synthase; Tumor Cells, Cultured | 2020 |
ATP13A2 deficiency disrupts lysosomal polyamine export.
Topics: Animals; Biocatalysis; Biological Transport; Caenorhabditis elegans; Cathepsin B; Cytosol; Disease Models, Animal; Endocytosis; Humans; Lysosomes; Mice; Mutation; Neurons; Phenotype; Polyamines; Proton-Translocating ATPases; Spermidine; Spermine | 2020 |
Polyamines and its analogue modulates amyloid fibrillation in lysozyme: A comparative investigation.
Topics: Amyloid; Amyloidosis; Animals; Avian Proteins; Biogenic Polyamines; Chickens; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Muramidase; Protein Aggregates; Protein Aggregation, Pathological; Spermidine; Spermine | 2020 |
Serendipitous Discovery of Leucine and Methionine Depletion Agents during the Search for Polyamine Transport Inhibitors.
Topics: Animals; Benzoxazoles; Biological Transport; CHO Cells; Cricetulus; Drug Discovery; Humans; Large Neutral Amino Acid-Transporter 1; Leucine; Methionine; Polyamines; Putrescine; Small Molecule Libraries; Spermidine; Spermine; Tyrosine | 2020 |
Interplay between 1-aminocyclopropane-1-carboxylic acid, γ-aminobutyrate and D-glucose in the regulation of high nitrate-induced root growth inhibition in maize.
Topics: Abscisic Acid; Amino Acids, Cyclic; Carbon; Cyclopentanes; Cytokinins; Ethylenes; Glucose; Indoleacetic Acids; Nitrates; Nitrogen; Oxylipins; Plant Growth Regulators; Plant Roots; Polyamines; Spermidine; Spermine; Zea mays | 2020 |
Polyamine stimulation perturbs intracellular Ca2+ homeostasis and decreases viability of breast cancer BT474 cells.
Topics: Breast Neoplasms; Calcium; Cell Line, Tumor; Cell Proliferation; Cell Survival; Endoplasmic Reticulum Stress; Female; Gene Expression Regulation, Neoplastic; Homeostasis; Humans; Polyamines; Putrescine; Receptors, Calcium-Sensing; Spermidine; Spermine | 2020 |
Separation and Characterization of Phenolamines and Flavonoids from Rape Bee Pollen, and Comparison of Their Antioxidant Activities and Protective Effects Against Oxidative Stress.
Topics: Alanine Transaminase; Amidines; Animals; Antioxidants; Aspartate Aminotransferases; Bees; Benzothiazoles; Biphenyl Compounds; Gene Expression; Glutathione; Glycosides; Hep G2 Cells; Humans; Kaempferols; Oxidants; Oxidative Stress; Picrates; Plant Extracts; Pollen; Quercetin; Reactive Oxygen Species; Spermidine; Spermine; Sulfonic Acids; Superoxide Dismutase | 2020 |
Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice.
Topics: Animals; Autophagy; Brain; Cellular Senescence; Dementia; Disease Models, Animal; Mice; Mitochondria; Oxidative Stress; Spermidine; Spermine | 2020 |
SpeG polyamine acetyltransferase enzyme from Bacillus thuringiensis forms a dodecameric structure and exhibits high catalytic efficiency.
Topics: Acetyltransferases; Bacillus thuringiensis; Catalysis; Kinetics; Polyamines; Spermidine; Spermine | 2020 |
Polyamine blockade and binding energetics in the MthK potassium channel.
Topics: Electrophysiological Phenomena; Kinetics; Polyamines; Potassium; Potassium Channels, Inwardly Rectifying; Spermidine; Spermine | 2020 |
Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling.
Topics: Adenocarcinoma; Animals; beta Catenin; Cell Transformation, Neoplastic; DNA Damage; Gastritis; Helicobacter Infections; Helicobacter pylori; Mice; Mice, Inbred C57BL; Mice, Knockout; Organoids; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Proteome; RNA, Messenger; Signal Transduction; Spermidine; Spermine; Stomach Neoplasms | 2020 |
The alleviating effect of exogenous polyamines on heat stress susceptibility of different heat resistant wheat (Triticum aestivum L.) varieties.
Topics: Disease Resistance; Heat-Shock Response; Hot Temperature; Oxidoreductases; Plant Proteins; Spermidine; Spermine; Triticum | 2020 |
The unknown soldier in citrus plants: polyamines-based defensive mechanisms against biotic and abiotic stresses and their relationship with other stress-associated metabolites.
Topics: Citrus; Polyamines; Spermidine; Spermine; Stress, Physiological; Xanthomonas; Xylella | 2020 |
Polyamines stimulate RecA-mediated recombination by condensing duplex DNA and stabilizing intermediates.
Topics: DNA; Immobilized Nucleic Acids; Rec A Recombinases; Recombination, Genetic; Spermidine; Spermine | 2020 |
Spermine and spermidine modulate T-cell function in older adults with and without cognitive decline ex vivo.
Topics: Aged; Aged, 80 and over; Aging; Autophagy; Case-Control Studies; Cognitive Dysfunction; Cytokines; Dementia; Dietary Supplements; Down-Regulation; Female; Healthy Volunteers; Humans; Lymphocyte Activation; Male; Spermidine; Spermine; T-Lymphocytes | 2020 |
Understanding the influence of trenbolone acetate and polyamines on proliferation of bovine satellite cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Cattle; Cell Proliferation; Dicarboxylic Acid Transporters; Gene Expression Regulation; Methionine; Mitochondrial Membrane Transport Proteins; Ornithine; Satellite Cells, Skeletal Muscle; Spermidine; Spermine; Trenbolone Acetate | 2021 |
Discovery of Potent Charge-Reducing Molecules for Native Ion Mobility Mass Spectrometry Studies.
Topics: Cation Transport Proteins; Escherichia coli; Escherichia coli Proteins; Histamine; Ligands; Mass Spectrometry; Methylamines; Protein Binding; Spermidine; Spermine; Static Electricity | 2020 |
Effects of nitric oxide on the GABA, polyamines, and proline in tea (Camellia sinensis) roots under cold stress.
Topics: Camellia sinensis; Carboxy-Lyases; Cold Temperature; Cold-Shock Response; Cyclic N-Oxides; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Imidazoles; Nitric Oxide; Nitric Oxide Donors; Ornithine Decarboxylase; Plant Leaves; Plant Proteins; Plant Roots; Polyamines; Proline; Putrescine; S-Nitroso-N-Acetylpenicillamine; Spermidine; Spermine; Tea | 2020 |
Triggering doxorubicin release from responsive hydrogel films by polyamine uptake.
Topics: Doxorubicin; Hydrogels; Methylgalactosides; Polyamines; Spermidine; Spermine | 2020 |
ESI-Q-TOF-MS determination of polyamines and related enzyme activity for elucidating cellular polyamine metabolism.
Topics: Animals; Carbon Isotopes; Enzyme Activation; Enzymes; Isotope Labeling; Liver; Male; Methionine; Polyamines; Rats; Spectrometry, Mass, Electrospray Ionization; Spermidine; Spermine | 2020 |
The involvement of polyamine uptake and synthesis pathways in the proliferation of neonatal astrocytes.
Topics: Animals; Astrocytes; Cell Proliferation; Cells, Cultured; Eflornithine; Polyamines; Protein Transport; Rats; Rats, Sprague-Dawley; Spermidine; Spermine | 2020 |
Putrescine elicits ROS-dependent activation of the salicylic acid pathway in Arabidopsis thaliana.
Topics: Arabidopsis; Cadaverine; Gene Expression Profiling; Plant Growth Regulators; Plant Leaves; Putrescine; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Salicylic Acid; Signal Transduction; Spermidine; Spermine | 2020 |
K+ promotes the favorable effect of polyamine on gene expression better than Na.
Topics: Biochemical Phenomena; DNA; Gene Expression; Polyamines; Potassium; Sodium; Spermidine; Spermine | 2020 |
Polyamine regulation of porcine reproductive and respiratory syndrome virus infection depends on spermidine-spermine acetyltransferase 1.
Topics: Acetyltransferases; Animals; Cell Line; Down-Regulation; Gene Expression Regulation; Host Microbial Interactions; Kidney; Polyamines; Porcine respiratory and reproductive syndrome virus; Spermidine; Spermine; Swine; Up-Regulation; Virus Replication | 2020 |
Removal of biogenic amines from wines by chemisorption on functionalized silica and effects on other wine components.
Topics: Adsorption; Biogenic Amines; Cadaverine; Food Handling; Histamine; Putrescine; Silicon Dioxide; Spermidine; Spermine; Wine | 2020 |
Digestive involvement in a severe form of Snyder-Robinson syndrome: Possible expansion of the phenotype.
Topics: Child, Preschool; Failure to Thrive; Humans; Infant; Jejunum; Male; Mental Retardation, X-Linked; Mutation, Missense; Phenotype; Spermidine; Spermine; Spermine Synthase | 2021 |
Dietary Polyamines Intake and Risk of Colorectal Cancer: A Case-Control Study.
Topics: Adult; Aged; Case-Control Studies; China; Colonic Neoplasms; Diet; Female; Humans; Male; Middle Aged; Odds Ratio; Polyamines; Putrescine; Rectal Neoplasms; Risk Factors; Spermidine; Spermine | 2020 |
Polyamines serum levels in episodic and chronic migraine.
Topics: Humans; Migraine Disorders; Polyamines; Putrescine; Spermidine; Spermine | 2021 |
Spermine and Spermidine Priming against
Topics: Antifungal Agents; Arabidopsis; Ascorbate Peroxidases; Asparagine; Botrytis; Catalase; Disease Resistance; Fructose; gamma-Aminobutyric Acid; Gene Expression Regulation, Plant; Glucose; Hydrogen Peroxide; Nitrate Reductase; Peroxidase; Phenylalanine; Plant Diseases; Plant Growth Regulators; Plant Immunity; Plant Leaves; Spermidine; Spermine; Sucrose | 2021 |
Application of gold and silver nanoparticles for selective assay of spermine in mixture with spermidine.
Topics: Gold; Humans; Metal Nanoparticles; Silver; Spectrophotometry; Spermidine; Spermine | 2021 |
Effects of Spermine and Spermidine supplemented extenders on post-thaw Spermatological Parameters in Stallion Semen Cryopreservation.
Topics: Animals; Cryopreservation; Cryoprotective Agents; Female; Horses; Humans; Male; Semen; Semen Preservation; Sperm Motility; Spermatozoa; Spermidine; Spermine | 2021 |
Polyamine-Rich Diet Elevates Blood Spermine Levels and Inhibits Pro-Inflammatory Status: An Interventional Study.
Topics: Animals; Diet; Lymphocyte Function-Associated Antigen-1; Male; Mice; Polyamines; Spermidine; Spermine | 2021 |
N1-acetylspermidine is a determinant of hair follicle stem cell fate.
Topics: Acetyltransferases; Cell Differentiation; Hair Follicle; Spermidine; Spermine; Stem Cells | 2021 |
Sinularamides A-G, Terpenoid-Derived Spermidine and Spermine Conjugates with Casitas B-Lineage Lymphoma Proto-Oncogene B (Cbl-b) Inhibitory Activities from a
Topics: Adaptor Proteins, Signal Transducing; Animals; Anthozoa; Molecular Structure; Palau; Proto-Oncogene Proteins c-cbl; Spermidine; Spermine; Terpenes | 2021 |
Determination of 8 biogenic amines in aquatic products and their derived products by high-performance liquid chromatography-tandem mass spectrometry without derivatization.
Topics: Biogenic Amines; Cadaverine; Chromatography, High Pressure Liquid; Histamine; Phenethylamines; Putrescine; Seafood; Spermidine; Spermine; Tandem Mass Spectrometry; Tryptamines; Tyramine | 2021 |
SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
Topics: Animals; Antinematodal Agents; Autophagosomes; Autophagy; Autophagy-Related Proteins; Cells, Cultured; Chlorocebus aethiops; COVID-19; COVID-19 Drug Treatment; Cricetinae; Disease Models, Animal; Humans; Lung; Metabolome; Niclosamide; Organoids; SARS-CoV-2; Spermidine; Spermine | 2021 |
Ectopic Expression of
Topics: Adenosylmethionine Decarboxylase; Arabidopsis; Arabidopsis Proteins; Ectopic Gene Expression; Gene Expression Regulation, Plant; Plants, Genetically Modified; Salt Tolerance; Spermidine; Spermine | 2021 |
The Acinetobacter baumannii disinfectant resistance protein, AmvA, is a spermidine and spermine efflux pump.
Topics: Acinetobacter baumannii; Bacterial Proteins; Disinfectants; Drug Resistance, Multiple, Bacterial; Spermidine; Spermine | 2021 |
Influence of Breastfeeding Factors on Polyamine Content in Human Milk.
Topics: Adolescent; Adult; Age Factors; Birth Weight; Body Mass Index; Breast Feeding; Chromatography, High Pressure Liquid; Cohort Studies; Delivery, Obstetric; Female; Humans; Infant; Infant, Newborn; Mexico; Milk, Human; Mothers; Polyamines; Putrescine; Spermidine; Spermine; Young Adult | 2021 |
Structure of Pseudomonas aeruginosa spermidine dehydrogenase: a polyamine oxidase with a novel heme-binding fold.
Topics: Heme; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Pseudomonas aeruginosa; Spermidine; Spermine | 2022 |
The critical role of the aldehyde dehydrogenase PauC in spermine, spermidine, and diaminopropane toxicity in Pseudomonas aeruginosa: Its possible use as a drug target.
Topics: Aldehyde Dehydrogenase; Humans; Polyamines; Pseudomonas aeruginosa; Putrescine; Spermidine; Spermine | 2022 |
Polyamine Metabolism under Different Light Regimes in Wheat.
Topics: Light; Photosynthesis; Plant Leaves; Polyamines; Putrescine; Spermidine; Spermine; Triticum | 2021 |
Exogenously applied Spd and Spm enhance drought tolerance in tea plants by increasing fatty acid desaturation and plasma membrane H
Topics: Cell Membrane; Droughts; Fatty Acids; Proton-Translocating ATPases; Spermidine; Spermine; Tea | 2022 |
Solid-Supported Amplification of Aggregation Emission: A Tetraphenylethylene-Cucurbit[6]uril@Hydroxyapatite-Based Supramolecular Sensing Assembly for the Detection of Spermine and Spermidine in Human Urine and Blood.
Topics: Biocompatible Materials; Durapatite; Heterocyclic Compounds, 2-Ring; Humans; Imidazolidines; Macrocyclic Compounds; Macromolecular Substances; Materials Testing; Molecular Structure; Particle Size; Spermidine; Spermine; Stilbenes | 2021 |
Polyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells.
Topics: Animals; Apoptosis; Cytophagocytosis; Female; Healthy Volunteers; Humans; Immunomodulation; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Polyamines; Signal Transduction; Spermidine; Spermine | 2022 |
Enhanced antibacterial, antioxidant and anticancer activity of caffeic acid by simple acid-base complexation with spermine/spermidine.
Topics: Anti-Bacterial Agents; Antioxidants; Spectroscopy, Fourier Transform Infrared; Spermidine; Spermine; Water | 2022 |
Polyamines effectively mitigate senescence in persistent leaves of
Topics: Plant Breeding; Plant Leaves; Polyamines; Spermidine; Spermine | 2023 |
Determination of spermine and spermidine in meat with a ratiometric fluorescence nanoprobe and a combinational logic gate.
Topics: Carbon; Fluorescence; Fluorescent Dyes; Meat; Penicillins; Quantum Dots; Spermidine; Spermine | 2022 |
ATP13A3 facilitates polyamine transport in human pancreatic cancer cells.
Topics: Adenosine Triphosphatases; Animals; Biological Transport; Humans; Mammals; Membrane Transport Proteins; Pancreatic Neoplasms; Polyamines; Spermidine; Spermine | 2022 |
A Second Gamma-Glutamylpolyamine Synthetase, GlnA2, Is Involved in Polyamine Catabolism in
Topics: Cadaverine; Ligases; Polyamines; Putrescine; Spermidine; Spermine; Streptomyces coelicolor | 2022 |
Availability of polyamines affects virulence and survival of Neisseria meningitidis.
Topics: Animals; Humans; Mice; Neisseria meningitidis; Polyamines; Spermidine; Spermine; Virulence | 2022 |
Consecutive action of two BAHD acyltransferases promotes tetracoumaroyl spermine accumulation in chicory.
Topics: Acyltransferases; Alkenes; Aza Compounds; Cichorium intybus; Spermidine; Spermine | 2022 |
Altered Brain Arginine Metabolism and Polyamine System in a P301S Tauopathy Mouse Model: A Time-Course Study.
Topics: Animals; Arginine; Brain; Mice; Polyamines; Putrescine; Spermidine; Spermine; Tauopathies | 2022 |
Metabolomics and lipidomics insight into the effect of different polyamines on tomato plants under non-stress and salinity conditions.
Topics: Lipidomics; Plant Roots; Polyamines; Putrescine; Salinity; Solanum lycopersicum; Spermidine; Spermine | 2022 |
Phenylbutyrate modulates polyamine acetylase and ameliorates Snyder-Robinson syndrome in a Drosophila model and patient cells.
Topics: Acetyl Coenzyme A; Acetylesterase; Acetyltransferases; Animals; Drosophila; Mental Retardation, X-Linked; Phenylbutyrates; Polyamines; Spermidine; Spermine | 2022 |
Exogenous spermidine regulates the anaerobic enzyme system through hormone concentrations and related-gene expression in Phyllostachys praecox roots under flooding stress.
Topics: Abscisic Acid; Anaerobiosis; Ethylenes; Gene Expression; Hormones; Hydrogen Peroxide; Hypoxia; Indoleacetic Acids; Polyamines; Putrescine; Spermidine; Spermine | 2022 |
Light Spectral Composition Modifies Polyamine Metabolism in Young Wheat Plants.
Topics: Plant Leaves; Polyamines; Putrescine; Spermidine; Spermine; Triticum | 2022 |
Utilization of Aminoguanidine Prevents Cytotoxic Effects of Semen.
Topics: Guanidines; Humans; Oxidoreductases; Polyamines; Semen; Serum; Serum Albumin, Bovine; Spermidine; Spermine | 2022 |
The role of ethylene signalling in the regulation of salt stress response in mature tomato fruits: Metabolism of antioxidants and polyamines.
Topics: Antioxidants; Ascorbate Peroxidases; Catalase; Ethylenes; Fruit; Glutathione; Hydrogen Peroxide; Polyamines; Putrescine; Salt Stress; Sodium Chloride; Solanum lycopersicum; Spermidine; Spermine; Superoxide Dismutase | 2022 |
Reduction of biogenic amines formation by foodborne pathogens using postbiotics in lysine-decarboxylase broth.
Topics: Agmatine; Ammonia; Biogenic Amines; Butyrates; Cadaverine; Carboxy-Lyases; Escherichia coli; Lactococcus lactis; Lysine; Putrescine; Spermidine; Spermine | 2022 |
A combination of a graphene quantum dots-cationic red dye donor-acceptor pair and cucurbit[7]uril as a supramolecular sensor for ultrasensitive detection of cancer biomarkers spermine and spermidine.
Topics: Amino Acids; Biomarkers, Tumor; Cations; Graphite; Humans; Neoplasms; Quantum Dots; Spermidine; Spermine | 2022 |
Elucidating the Role of
Topics: Animals; Drosophila melanogaster; Eflornithine; Polyamines; Putrescine; Spermidine; Spermine | 2022 |
Identification and Characterization of Novel Small-Molecule SMOX Inhibitors.
Topics: Acrolein; Flavins; Hydrogen Peroxide; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Spermidine; Spermine | 2022 |
Understanding the Polyamine and mTOR Pathway Interaction in Breast Cancer Cell Growth.
Topics: Breast Neoplasms; Female; Humans; Mechanistic Target of Rapamycin Complex 1; Phosphatidylinositol 3-Kinases; Polyamines; Proto-Oncogene Proteins c-akt; Putrescine; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Small Interfering; Spermidine; Spermine; TOR Serine-Threonine Kinases | 2022 |
Renal Metabolome in Obese Mice Treated with Empagliflozin Suggests a Reduction in Cellular Respiration.
Topics: Animals; Aspartic Acid; Benzhydryl Compounds; Cell Respiration; Flavin Mononucleotide; Glucosides; Kidney; Male; Metabolome; Mice; Mice, Obese; Phosphatidic Acids; Phosphatidylcholines; Phosphoenolpyruvate; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Spermidine; Spermine; Succinates; Urea; Uridine | 2022 |
Mitochondrial Spermidine Synthase is Essential for Blood-stage growth of the Malaria Parasite.
Topics: Animals; Malaria; Mitochondria; Parasites; Plasmodium falciparum; Polyamines; Putrescine; Spermidine; Spermidine Synthase; Spermine | 2022 |
Spermine Suppresses Adipocyte Differentiation and Exerts Anti-Obesity Effects In Vitro and In Vivo.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Cell Differentiation; Lipids; Mice; Obesity; Polyamines; Putrescine; RNA, Messenger; Spermidine; Spermine | 2022 |
Integrated Multi-Omic Characterization of the Detachment Process of Adherent Vero Cells with Animal-Based and Animal-Origin-Free Enzymes.
Topics: Animals; Chlorocebus aethiops; Electron Transport Complex IV; Proteomics; Spermidine; Spermine; Vero Cells | 2022 |
Alkaline Stress Causes Changes in Polyamine Biosynthesis in
Topics: Polyamines; Putrescine; Spermidine; Spermine; Thermus thermophilus | 2022 |
Polyamines conjugated to deoxyribonucleic acid-protein in cell nucleus from filling grain embryos were involved in tolerance of wheat to drought.
Topics: Cell Nucleus; DNA; Droughts; Edible Grain; Polyamines; Putrescine; Spermidine; Spermine; Triticum | 2022 |
Thermal tolerance role of novel polyamine, caldopentamine, identified in fifth instar Bombyx mori.
Topics: Animals; Bombyx; Polyamines; Putrescine; Spermidine; Spermine | 2023 |
Quantitative Metabolomics to Explore the Role of Plasma Polyamines in Colorectal Cancer.
Topics: Chromatography, Liquid; Colorectal Neoplasms; Humans; Polyamines; Spermidine; Spermine | 2022 |
Influence of Brewing Process on the Profile of Biogenic Amines in Craft Beers.
Topics: Beer; Biogenic Amines; Chromatography, High Pressure Liquid; Spermidine; Spermine | 2022 |
Evaluation of the stability of polyamines in human serum at different storage temperatures using capillary electrophoresis with indirect ultraviolet detection.
Topics: Cadaverine; Electrophoresis, Capillary; Humans; Polyamines; Putrescine; Spermidine; Spermine; Temperature | 2023 |
Biochemical and structural basis of polyamine, lysine and ornithine acetylation catalyzed by spermine/spermidine N-acetyl transferase in moss and maize.
Topics: Acetylation; Acetyltransferases; Animals; Catalysis; Humans; Lysine; Mammals; Ornithine; Polyamines; Spermidine; Spermine; Zea mays | 2023 |
Effects of putrescine on oxidative stress, spermidine/spermine-N(1)-acetyltransferase, inflammation and energy levels in liver and serum in rats with brain ischemia-reperfusion.
Topics: Acetyltransferases; Animals; Brain Ischemia; Inflammation; Liver; Male; Oxidative Stress; Putrescine; Rats; Rats, Wistar; Reperfusion; Spermidine; Spermine | 2023 |
Novel Green Fluorescent Polyamines to Analyze ATP13A2 and ATP13A3 Activity in the Mammalian Polyamine Transport System.
Topics: Adenosine Triphosphatases; Animals; Biological Transport; Boron Compounds; Fluorescent Dyes; Mammals; Polyamines; Putrescine; Spermidine; Spermine | 2023 |
Supramolecular fluorescent probe based on acyclic cucurbituril for detection of cancer Labels in human urine.
Topics: Copper; Fluorescent Dyes; Humans; Neoplasms; Spectrometry, Fluorescence; Spermidine; Spermine | 2023 |
Spermidine dietary supplementation and polyamines level in reference to survival and lifespan of honey bees.
Topics: Animals; Bees; Dietary Supplements; Longevity; Polyamines; Putrescine; Spermidine; Spermine | 2023 |
Enhanced cell growth, production, and mAb quality produced in Chinese hamster ovary-K1 cells by supplementing polyamine in the media.
Topics: Animals; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Polyamines; Putrescine; Spermidine; Spermine | 2023 |
Putrescine transformation to other forms of polyamines in filling grain embryos functioned in enhancing the resistance of maize plants to drought stress.
Topics: Droughts; Edible Grain; Polyamines; Putrescine; Spermidine; Spermine; Zea mays | 2023 |
Putrescine supplementation shifts macrophage L-arginine metabolism related-genes reducing Leishmania amazonensis infection.
Topics: Animals; Arginine; Dietary Supplements; Leishmania; Leishmaniasis; Macrophages; Mice; Nitric Oxide Synthase; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 2023 |
A Fine-Tuning of the Plant Hormones, Polyamines and Osmolytes by Ectomycorrhizal Fungi Enhances Drought Tolerance in Pedunculate Oak.
Topics: Abscisic Acid; Betaine; Drought Resistance; Droughts; Mycorrhizae; Plant Growth Regulators; Polyamines; Proline; Quercus; Spermidine; Spermine | 2023 |
Strikingly conserved gene expression changes of polyamine regulating enzymes among various forms of acute and chronic kidney injury.
Topics: Acetyltransferases; Amine Oxidase (Copper-Containing); Animals; Gene Expression; Humans; Kidney; Mice; Polyamines; Putrescine; Reperfusion Injury; Spermidine; Spermine | 2023 |
Evaluating biogenic amines and pH levels in farmed rainbow trout (
Topics: Animals; Biogenic Amines; Cadaverine; Histamine; Hydrogen-Ion Concentration; Oncorhynchus mykiss; Putrescine; Spermidine; Spermine; Tryptamines; Tyramine | 2023 |
Age-associated polyamines in peripheral blood cells and plasma in 20 to 70 years of age subjects.
Topics: Animals; Blood Cells; Female; Male; Polyamines; Putrescine; Spermidine; Spermine | 2023 |
Polyamine catabolism is concentrated in tumor-associated histiocytes in diffuse large B-cell lymphoma and classic Hodgkin lymphoma.
Topics: Histiocytes; Hodgkin Disease; Humans; Lymphoma, Large B-Cell, Diffuse; Polyamines; Spermidine; Spermine | 2023 |
Topics: Biogenic Polyamines; Homeostasis; Polyamines; Spermidine; Spermine | 2023 |
Spermine and spermidine bind CXCR4 and inhibit CXCR4- but not CCR5-tropic HIV-1 infection.
Topics: Cell Line; HIV Infections; HIV-1; Humans; Receptors, CXCR4; Spermidine; Spermine | 2023 |
Regulation of synthesis of polyamines by progesterone, estradiol, and their receptors in uteri of cyclic ewes†.
Topics: Animals; Estradiol; Female; Flushing; Mammals; Polyamines; Progesterone; Receptors, Progesterone; Sheep; Spermidine; Spermine; Uterus | 2023 |
Structural and Kinetic Characterization of the SpeG Spermidine/Spermine
Topics: Acetyltransferases; Methicillin-Resistant Staphylococcus aureus; Polyamines; Spermidine; Spermine | 2023 |
As Verified with the Aid of Biotinylated Spermine, the Brain Cannot Take up Polyamines from the Bloodstream Leaving It Solely Dependent on Local Biosynthesis.
Topics: Brain; Neurons; Polyamines; Spermidine; Spermine | 2023 |
Correlation analysis of polyamine metabolism and reproductive hormone levels in goose ovarian follicles.
Topics: Animals; Estradiol; Female; Geese; Ovarian Follicle; Progesterone; Putrescine; Spermidine; Spermine | 2023 |
Polyamine-producing bacteria inhibit the absorption of Cd by spinach and alter the bacterial community composition of rhizosphere soil.
Topics: Bacillus megaterium; Cadmium; Polyamines; Rhizosphere; Spermidine; Spermine; Spinacia oleracea | 2023 |
Inhibition of Polyamine Catabolism Reduces Cellular Senescence.
Topics: Aging; Cellular Senescence; Humans; Polyamines; Spermidine; Spermine | 2023 |
Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder-Robinson syndrome.
Topics: Eflornithine; Humans; Male; Polyamines; Spermidine; Spermine; Spermine Synthase | 2023 |
Evidence of polyamines mediated 2-acetyl-1-pyrroline biosynthesis in aromatic rice rhizospheric fungal species Aspergillus niger.
Topics: Aspergillus niger; Ornithine Decarboxylase; Oryza; Polyamines; Putrescine; Spermidine; Spermine | 2023 |
Polyamines modulate mouse sperm motility.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Male; Mice; Polyamines; Putrescine; Semen; Sperm Motility; Spermidine; Spermine | 2023 |
Improving postharvest life, quality and bioactive compounds of strawberry fruits using spermine and spermidine.
Topics: Antioxidants; Fragaria; Fruit; Spermidine; Spermine | 2023 |
Enriched endogenous free Spd and Spm in alfalfa (Medicago sativa L.) under drought stress enhance drought tolerance by inhibiting H
Topics: Antioxidants; Drought Resistance; Droughts; Hydrogen Peroxide; Medicago sativa; Peroxidases; Polyamines; Putrescine; Spermidine; Spermine; Superoxide Dismutase | 2023 |