spermine and pimagedine

spermine has been researched along with pimagedine in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19906 (20.00)18.7374
1990's12 (40.00)18.2507
2000's10 (33.33)29.6817
2010's1 (3.33)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Brunton, VG; Grant, MH; Wallace, HM1
Clark, DA; Daya, S; Lea, RG1
Gilad, GM; Gilad, VH1
Beninati, S; Folk, JE; Martinet, N; Piacentini, M1
Burke, M; Chayen, R; Goldberg, S1
Deen, DF; Hung, DT; Marton, LJ; Oredsson, SM; Pegg, AE1
Bellett, AJ; Braithwaite, AW; Cheetham, BF; Waldron-Stevens, LK1
Chan, WY; Gittos, MW; Griesmann, G; Knödgen, B; Rennert, OM; Seiler, N1
Litwin, MS; Lu, Y; Smith, RC; Zetter, BR1
Nilsson, BO; Rosengren, E1
Chapman, GE; Wallace, HM1
Aziz, SM; Crooks, PA; Gillespie, MN; Gosland, MP; Olson, JW; Tofiq, S; Tsuboi, CP1
Barlier, AM; Benamouzig, R; Tomé, D1
Ferro, TJ; Gertzberg, N; Johnson, A; Neumann, P; Selden, L1
LeDoux, SP; Patton, NJ; Wilson, GL1
de Hoog, E; Dorhout, B; Kingma, AW; Muskiet, FA; Poortenga, PJ1
Hu, WH; Jen, MF; Li, F; Liao, WH; Liu, JS; Liu, N; Qiang, WA; Wang, GQ; Xiao, J1
Shah, N; Shirahata, A; Sigal, LH; Thomas, T; Thomas, TJ1
Ram, JL; Speyer, CL; Steffes, CP; Tyburski, JG1
Badolo, L; Duranton, B; Gossé, F; Raul, F; Schneider, Y; Seiler, N; Vincent, F1
Herrero-Fresneda, I; Lloberas, N; Ma Cruzado, J; Ma Grinyó, J; Riera, M; Torras, J1
Beckman, DL; Liu, L; Mehta, P; Sun, P; Wang, J1
Casero, RA; Kensler, TW; Kwak, MK1
Kang, JH; Nahm, CH; Park, CS; Ryu, SD; Yi, HG1
Gavin, IM; Glesne, D; Huberman, E; Kubera, C; Zhao, Y1
Berberich, T; Kusano, T; Mitsuya, Y; Miyazaki, A; Takahashi, H; Takahashi, Y; Uehara, Y1
Casero, RA; Hacker, A; Mackintosh, CA; Pegg, AE; Rider, JE; Woster, PM1
Calvert, TJ; Chicoine, LG; Liu, Y; Nelin, LD1
Fujii, N; Hanashima, S; Imamaki, R; Kaneda, M; Kitazume, S; Kurbangalieva, A; Oishi, S; Tanaka, K; Taniguchi, N; Tsutsui, A; Yamaguchi, Y1
Deniz, M; Groß, R; Harms, M; Mayer, B; Müller, J; Münch, J; von Maltitz, P1

Other Studies

30 other study(ies) available for spermine and pimagedine

ArticleYear
Mechanisms of spermine toxicity in baby-hamster kidney (BHK) cells. The role of amine oxidases and oxidative stress.
    The Biochemical journal, 1991, Nov-15, Volume: 280 ( Pt 1)

    Topics: Animals; Carmustine; Catalase; Cell Line; Cell Survival; Cricetinae; Glutathione Reductase; Guanidines; Kidney; Kinetics; Models, Biological; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Spermine

1991
Identification of low molecular weight immunosuppressor molecules in human in vitro fertilization supernatants predictive of implantation as a polyamine--possibly spermine.
    Fertility and sterility, 1990, Volume: 53, Issue:5

    Topics: Centrifugation; Chromatography, High Pressure Liquid; Culture Media; Culture Techniques; Cytotoxicity Tests, Immunologic; Embryo, Mammalian; Female; Fertilization in Vitro; Forecasting; Guanidines; Humans; Hydroxylamine; Hydroxylamines; Immune System; Molecular Weight; Monoamine Oxidase Inhibitors; Polyamines; Spermine

1990
Polyamines affect growth of cultured rat cerebellar neurons in different sera.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1986, Volume: 4, Issue:3

    Topics: Animals; Blood Proteins; Cattle; Cell Division; Cell Survival; Cerebellum; Eflornithine; Guanidines; Humans; Polyamines; Rats; Species Specificity; Spermine; Thymidine

1986
Free and protein-conjugated polyamines in mouse epidermal cells. Effect of high calcium and retinoic acid.
    The Journal of biological chemistry, 1988, Mar-15, Volume: 263, Issue:8

    Topics: Animals; Calcium; Cells, Cultured; Guanidines; Kinetics; Mice; Mice, Inbred BALB C; Polyamines; Protein Binding; Proteins; Putrescine; Skin; Spermidine; Spermine; Tretinoin

1988
Excretion of polyamines by humans following inhibition of diamine oxidase.
    Israel journal of medical sciences, 1985, Volume: 21, Issue:6

    Topics: Amine Oxidase (Copper-Containing); Cadaverine; Creatine; Guanidines; Humans; Male; Polyamines; Putrescine; Spermidine; Spermine

1985
Potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity in 9L rat brain tumor cells by methylglyoxal-bis(guanylhydrazone), an inhibitor of S-adenosyl-L-methionine decarboxylase.
    European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Animals; Brain Neoplasms; Carboxy-Lyases; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Guanidines; Mitoguazone; Putrescine; Rats; Spermidine; Spermine

1984
Spermine and aminoguanidine protect cells from chromosome aberrations induced by adenovirus during the G2 phase of the cell cycle.
    Chromosoma, 1982, Volume: 84, Issue:4

    Topics: Adenoviridae; Animals; Cell Transformation, Viral; Cells, Cultured; Chromosome Aberrations; Dose-Response Relationship, Drug; Embryo, Mammalian; Guanidines; Interphase; Rats; Skin; Spermine

1982
On the formation of amino acids deriving from spermidine and spermine.
    The Biochemical journal, 1981, Oct-15, Volume: 200, Issue:1

    Topics: Amino Acids; Amino Acids, Diamino; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Guanidines; In Vitro Techniques; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Pargyline; Rats; Rats, Inbred Strains; Spermidine; Spermine

1981
Identification of an endogenous inhibitor of prostatic carcinoma cell growth.
    Nature medicine, 1995, Volume: 1, Issue:10

    Topics: Adenocarcinoma; Animals; Enzyme Inhibitors; Growth Inhibitors; Guanidines; Humans; Male; Neoplasm Invasiveness; Prostate; Prostatic Neoplasms; Putrescine; Rats; Spermine; Tissue Extracts; Tumor Cells, Cultured

1995
Putrescine level in blood from the rat portal vein is influenced by inhibition of diamine oxidase.
    Acta physiologica Scandinavica, 1995, Volume: 153, Issue:4

    Topics: Amine Oxidase (Copper-Containing); Animals; Female; Guanidines; Portal Vein; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine

1995
Spermine prevents lipid peroxidation induced by essential fatty acids in human breast cancer cells.
    Biochemical Society transactions, 1994, Volume: 22, Issue:4

    Topics: Breast Neoplasms; Cell Line; Docosahexaenoic Acids; Guanidines; Humans; Kinetics; Lipid Peroxidation; Spermine; Thiobarbituric Acid Reactive Substances; Tumor Cells, Cultured

1994
Reversal of doxorubicin, etoposide, vinblastine, and taxol resistance in multidrug resistant human sarcoma cells by a polymer of spermine.
    Cancer chemotherapy and pharmacology, 1996, Volume: 37, Issue:6

    Topics: Antineoplastic Agents; Doxorubicin; Drug Resistance, Multiple; Etoposide; Guanidines; Humans; Paclitaxel; Polymers; Sarcoma; Spermine; Tumor Cells, Cultured; Vinblastine

1996
Putrescine transport in differentiated Caco-2 cells.
    Gastroenterologie clinique et biologique, 1996, Volume: 20, Issue:2

    Topics: Biological Transport, Active; Caco-2 Cells; Cystamine; Enzyme Inhibitors; Guanidines; Humans; In Vitro Techniques; Mitoguazone; Putrescine; Spermidine; Spermine

1996
Endothelial barrier dysfunction and p42 oxidation induced by TNF-alpha are mediated by nitric oxide.
    The American journal of physiology, 1997, Volume: 272, Issue:5 Pt 1

    Topics: Actins; Animals; Antibodies; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Guanidines; Hydrazones; Molecular Weight; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Serum Albumin; Spermine; Tumor Necrosis Factor-alpha; Tyrosine

1997
Mitochondrial DNA in beta-cells is a sensitive target for damage by nitric oxide.
    Diabetes, 1997, Volume: 46, Issue:8

    Topics: Animals; Animals, Newborn; Autoradiography; Blotting, Southern; Cells, Cultured; DNA Damage; DNA, Mitochondrial; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Enzyme Inhibitors; Guanidines; Interleukin-1; Islets of Langerhans; Mutagens; Nitrites; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Spermine

1997
In vitro manipulation of L1210 cell cycle kinetics with 4-amidinoindan-1-one 2'-amidinohydrazone, alpha-difluoromethylornithine and N1-acetylspermine.
    Biochimica et biophysica acta, 1998, Jun-05, Volume: 1381, Issue:1

    Topics: Amidines; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Cell Cycle; DNA; Dose-Response Relationship, Drug; Eflornithine; Guanidines; Indans; Leukemia L1210; Mice; Spermine; Tumor Cells, Cultured

1998
Dual role for nitric oxide in dynorphin spinal neurotoxicity.
    Journal of neurotrauma, 1999, Volume: 16, Issue:1

    Topics: Animals; Arginine; Dose-Response Relationship, Drug; Dynorphins; Enzyme Inhibitors; Guanidines; Immunohistochemistry; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrogen Oxides; Rats; Rats, Wistar; Spermine; Spinal Cord; Time Factors

1999
Activation of nuclear factor kappaB by polyamines in breast cancer cells.
    Biochemistry, 1999, Nov-09, Volume: 38, Issue:45

    Topics: Breast Neoplasms; Circular Dichroism; Female; Guanidines; Humans; NF-kappa B; Polyamines; Protein Conformation; Putrescine; Spermidine; Spermine; Structure-Activity Relationship; Tumor Cells, Cultured

1999
Lipopolysaccharide induces relaxation in lung pericytes by an iNOS-independent mechanism.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 278, Issue:5

    Topics: Animals; Capillaries; Cell Size; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanidines; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Nitroprusside; omega-N-Methylarginine; Penicillamine; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Spermine; Vasodilator Agents

2000
Effect of the polyamine oxidase inactivator MDL 72527 on N(1)-(n-octanesulfonyl)spermine toxicity.
    The international journal of biochemistry & cell biology, 2000, Volume: 32, Issue:10

    Topics: Amine Oxidase (Copper-Containing); Animals; Caco-2 Cells; Calmodulin; Cell Cycle; Cell Death; Drug Synergism; Eflornithine; Guanidines; Humans; Molecular Structure; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Rats; Spermine; Sulfonamides; Trifluoperazine; Tumor Cells, Cultured

2000
Promising effects of ischemic preconditioning in renal transplantation.
    Kidney international, 2002, Volume: 61, Issue:6

    Topics: Animals; Cold Temperature; DNA; Enzyme Inhibitors; Guanidines; Hot Temperature; Ischemic Preconditioning; Kidney; Kidney Transplantation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Spermine; Time Factors

2002
Effect of nitric oxide on lung surfactant secretion.
    Experimental lung research, 2003, Volume: 29, Issue:5

    Topics: Animals; Carbazoles; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Guanidines; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrogen Oxides; Oxadiazoles; Perfusion; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; Quinoxalines; Rats; Rats, Sprague-Dawley; Spermine

2003
Induction of phase 2 enzymes by serum oxidized polyamines through activation of Nrf2: effect of the polyamine metabolite acrolein.
    Biochemical and biophysical research communications, 2003, Jun-06, Volume: 305, Issue:3

    Topics: Acrolein; Amine Oxidase (Copper-Containing); Animals; Antioxidants; Cell Line; Culture Media; DNA-Binding Proteins; Enzyme Induction; Enzyme Inhibitors; Enzymes; Guanidines; Keratinocytes; Mice; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidation-Reduction; Response Elements; RNA, Messenger; Signal Transduction; Spermidine; Spermine; Trans-Activators; Transcriptional Activation

2003
Hepatic flavin-containing monooxygenase activity attenuated by cGMP-independent nitric oxide-mediated mRNA destabilization.
    Biochemical and biophysical research communications, 2004, Nov-05, Volume: 324, Issue:1

    Topics: Animals; Cells, Cultured; Cyclic GMP; Cytokines; Dactinomycin; Guanidines; Hepatocytes; Lipopolysaccharides; Liver; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Oxygenases; Protein Modification, Translational; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA Stability; Spermine

2004
Spermine acts as a negative regulator of macrophage differentiation in human myeloid leukemia cells.
    Cancer research, 2004, Oct-15, Volume: 64, Issue:20

    Topics: Acetyltransferases; Apoptosis; Biogenic Polyamines; Cell Differentiation; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Guanidines; HL-60 Cells; Humans; Macrophages; NF-E2-Related Factor 2; Protein Kinase C; Protein Kinase C beta; Spermine; Tetradecanoylphorbol Acetate; Trans-Activators; U937 Cells

2004
Identification of a novel Cys2/His2-type zinc-finger protein as a component of a spermine-signaling pathway in tobacco.
    Journal of plant physiology, 2007, Volume: 164, Issue:6

    Topics: Amino Acid Sequence; Cell Nucleus; Green Fluorescent Proteins; Guanidines; Molecular Sequence Data; Nicotiana; Oxidation-Reduction; Oxidoreductases; Phylogeny; Plant Proteins; Polyamines; Putrescine; Sequence Alignment; Signal Transduction; Spermine; Tobacco Mosaic Virus; Transcription Factors; Up-Regulation; Zinc Fingers

2007
Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide.
    Amino acids, 2007, Volume: 33, Issue:2

    Topics: Animals; Apoptosis; Cells, Cultured; DNA Damage; Eflornithine; Glutathione; Guanidines; Hydrogen Peroxide; In Situ Nick-End Labeling; Mice; Oxidative Stress; Reactive Oxygen Species; Spermidine; Spermine

2007
Deficiency of mitogen-activated protein kinase phosphatase-1 results in iNOS-mediated hypotension in response to low-dose endotoxin.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4

    Topics: Animals; Blood Pressure; Breath Tests; Disease Models, Animal; Dose-Response Relationship, Drug; Dual Specificity Phosphatase 1; Enzyme Inhibitors; Guanidines; Hypotension; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Spermine; Time Factors; Up-Regulation

2008
Polyamine modification by acrolein exclusively produces 1,5-diazacyclooctanes: a previously unrecognized mechanism for acrolein-mediated oxidative stress.
    Organic & biomolecular chemistry, 2014, Jul-28, Volume: 12, Issue:28

    Topics: Acrolein; Amine Oxidase (Copper-Containing); Azocines; Cell Line, Tumor; Cell Survival; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Guanidines; HeLa Cells; Heme Oxygenase-1; Humans; Hydrogels; Oxidative Stress; Polymerization; Spermidine; Spermine

2014
Utilization of Aminoguanidine Prevents Cytotoxic Effects of Semen.
    International journal of molecular sciences, 2022, Aug-02, Volume: 23, Issue:15

    Topics: Guanidines; Humans; Oxidoreductases; Polyamines; Semen; Serum; Serum Albumin, Bovine; Spermidine; Spermine

2022