spermine has been researched along with opc 12759 in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Higaki, K; Hirota, M; Kimura, T; Minami, T; Miyake, M; Odomi, M; Ogawara, K; Toguchi, H | 1 |
| Higaki, K; Kimura, T; Minami, T; Miyake, M; Odomi, M; Ogawara, K; Toguchi, H | 1 |
| Higaki, K; Kimura, T; Miyake, M; Mukaizawa, F; Odomi, M; Ogawara, K; Taniguchi, K | 1 |
3 other study(ies) available for spermine and opc 12759
| Article | Year |
|---|---|
Novel oral formulation safely improving intestinal absorption of poorly absorbable drugs: utilization of polyamines and bile acids.
Topics: Adjuvants, Pharmaceutic; Administration, Oral; Alanine; Animals; Anti-Ulcer Agents; Area Under Curve; Biological Availability; Colon; Gastric Mucosa; Intestinal Absorption; Male; Quinolones; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Taurocholic Acid | 2006 |
Importance of bile acids for novel oral absorption system containing polyamines to improve intestinal absorption.
Topics: Alanine; Animals; Area Under Curve; Bile Acids and Salts; Bile Ducts; Biogenic Polyamines; Dogs; Intestinal Absorption; Ligation; Male; Quinolones; Rats; Rats, Sprague-Dawley; Spermine; Taurocholic Acid | 2006 |
Novel oral absorption system containing polyamines and bile salts enhances drug transport via both transcellular and paracellular pathways across Caco-2 cell monolayers.
Topics: Absorption; Adjuvants, Pharmaceutic; Administration, Oral; Alanine; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Drug Synergism; Electric Impedance; Epithelium; Humans; Mouth Mucosa; Patch-Clamp Techniques; Quinolones; Spermine; Taurocholic Acid | 2009 |