spermine has been researched along with kainic acid in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (60.00) | 18.2507 |
| 2000's | 9 (36.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anis, NA; Bukownik, R; Eldefrawi, AT; Eldefrawi, ME; Goodnow, RA; Nakanishi, K; Usherwood, PN | 1 |
| Carter, C; Fage, D; Scatton, B; Voltz, C | 1 |
| Brackley, P; Goodnow, R; Nakanishi, K; Sudan, HL; Usherwood, PN | 1 |
| Artigas, F; de Vera, N; Martínez, E | 1 |
| de Belleroche, J; Reed, LJ | 1 |
| Horimoto, N; Kawamoto, I; Nabekura, J; Ogawa, T | 1 |
| Donevan, SD; Rogawski, MA | 1 |
| Bowie, D; Mayer, ML | 1 |
| Baudry, M; Najm, I | 1 |
| Gilbert, E; Grimwood, S; Hutson, PH; Ragan, CI | 1 |
| Iino, M; Isa, T; Ozawa, S | 1 |
| Dingledine, R; Washburn, MS | 1 |
| Isa, T; Itazawa, SI; Ozawa, S | 1 |
| Dingledine, R; Numberger, M; Washburn, MS; Zhang, S | 1 |
| Bowie, D; Lange, GD; Mayer, ML | 1 |
| Anderson, CM; Chan, PH; Chen, Y; Copin, JC; Fahlman, CS; Stein, BA; Swanson, RA; Ying, W | 1 |
| Kim, CY; Lee, SR; Lee, YK | 1 |
| Mendonça-Silva, DL; Noël, F; Quintas, LE | 1 |
| Hu, GY; Zhang, JM | 1 |
| Endo, T; Isa, T | 1 |
| Callewaert, G; Robberecht, W; Van Damme, P; Van Den Bosch, L; Van Houtte, E | 1 |
| Camón, L; de Vera, N; Martínez, E | 1 |
| Bannerman, P; Feldman, D; Hahn, A; Horiuchi, M; Itoh, A; Itoh, T; Jia, ZP; Pleasure, D; See, J | 1 |
| Greenfield, LJ; Shen, G; Song, J; Tietz, EI | 1 |
| Gong, HQ; Jiang, XD; Liang, PJ; Liu, X; Sun, Y | 1 |
25 other study(ies) available for spermine and kainic acid
| Article | Year |
|---|---|
Synthesis and binding of [125I2]philanthotoxin-343, [125I2]philanthotoxin-343-lysine, and [125I2]philanthotoxin-343-arginine to rat brain membranes.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Iodine Radioisotopes; Kinetics; Male; Neurotoxins; Polyamines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Spermine; Synaptic Membranes; Wasp Venoms | 1991 |
Selective release of spermine and spermidine from the rat striatum by N-methyl-D-aspartate receptor activation in vivo.
Topics: Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dizocilpine Maleate; Kainic Acid; Male; Polyamines; Potassium; Putrescine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1992 |
Spermine and philanthotoxin potentiate excitatory amino acid responses of Xenopus oocytes injected with rat and chick brain RNA.
Topics: Amino Acids; Animals; Aspartic Acid; Bee Venoms; Brain; Chickens; Kainic Acid; Male; Membrane Potentials; Microinjections; N-Methylaspartate; Neurotoxins; Oocytes; Oxadiazoles; Poly A; Polyamines; Quisqualic Acid; Rats; Rats, Inbred Strains; RNA; RNA, Messenger; Spermine; Wasp Venoms; Xenopus | 1990 |
Differential response of rat brain polyamines to convulsant agents.
Topics: Animals; Biogenic Polyamines; Body Weight; Brain; Convulsants; Hexachlorocyclohexane; Kainic Acid; Male; Ornithine Decarboxylase; Pentylenetetrazole; Picrotoxin; Putrescine; Rats; Rats, Inbred Strains; Sesterterpenes; Spermidine; Spermine | 1991 |
Induction of ornithine decarboxylase in cerebral cortex by excitotoxin lesion of nucleus basalis: association with postsynaptic responsiveness and N-methyl-D-aspartate receptor activation.
Topics: Animals; Basal Ganglia; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Eflornithine; Enzyme Induction; Excitatory Amino Acid Antagonists; Glutamic Acid; Ibotenic Acid; Kainic Acid; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxazoles; Pentobarbital; Phosphatidylinositol Phosphates; Phosphatidylinositols; Putrescine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine; Substantia Innominata; Synapses | 1990 |
Developmental change of the potentiation of NMDA response by spermine.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Synergism; Electrophysiology; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Nystatin; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Spermine; Ventromedial Hypothalamic Nucleus | 1995 |
Intracellular polyamines mediate inward rectification of Ca(2+)-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Evoked Potentials; Hippocampus; Kainic Acid; Kinetics; Neurons; Patch-Clamp Techniques; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spermidine; Spermine; Time Factors | 1995 |
Inward rectification of both AMPA and kainate subtype glutamate receptors generated by polyamine-mediated ion channel block.
Topics: Calcium; Cell Line, Transformed; Glutamic Acid; Humans; Intracellular Fluid; Ion Channel Gating; Kainic Acid; Kidney; Magnesium; Membrane Potentials; Patch-Clamp Techniques; Putrescine; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Fusion Proteins; Spermidine; Spermine; Transfection | 1995 |
Kainate-induced seizure activity stimulates the polyamine interconversion pathway in rat brain.
Topics: Acetylation; Acetyltransferases; Animals; Biogenic Polyamines; Brain; Brain Chemistry; Kainic Acid; Male; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Rats; Rats, Sprague-Dawley; Seizures; Spermidine; Spermine | 1994 |
Modulation of 45Ca2+ influx into cells stably expressing recombinant human NMDA receptors by ligands acting at distinct recognition sites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Calcium; Calcium Radioisotopes; Cycloleucine; Dithionitrobenzoic Acid; Dithiothreitol; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Humans; Kainic Acid; L Cells; Ligands; Mice; Neurotoxins; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Spermine; Sulfhydryl Reagents | 1996 |
Spermine blocks synaptic transmission mediated by Ca(2+)-permeable AMPA receptors.
Topics: Animals; Calcium; Cells, Cultured; Excitatory Amino Acid Agonists; Extracellular Space; Hippocampus; Iontophoresis; Kainic Acid; Neurons; Patch-Clamp Techniques; Rats; Receptors, AMPA; Spermine; Synaptic Transmission | 1996 |
Block of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by polyamines and polyamine toxins.
Topics: Animals; Dose-Response Relationship, Drug; Kainic Acid; Male; Oocytes; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spermine; Xenopus | 1996 |
Inwardly rectifying and Ca2+-permeable AMPA-type glutamate receptor channels in rat neocortical neurons.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Calcium; Calcium Channels; Electric Conductivity; Excitatory Postsynaptic Potentials; In Vitro Techniques; Kainic Acid; Membrane Potentials; Nerve Fibers; Neurons; Occipital Lobe; Patch-Clamp Techniques; Rats; Receptors, AMPA; Receptors, GABA-A; Spermine; Synapses | 1997 |
Differential dependence on GluR2 expression of three characteristic features of AMPA receptors.
Topics: Animals; Calcium; Excitatory Amino Acid Agonists; Hippocampus; Indoleacetic Acids; Interneurons; Kainic Acid; Male; Oocytes; Patch-Clamp Techniques; Phenotype; Phenylacetates; Polyamines; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Recombinant Proteins; RNA, Messenger; Spermine; Spider Venoms; Synapses; Xenopus | 1997 |
Activity-dependent modulation of glutamate receptors by polyamines.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cells, Cultured; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ion Channel Gating; Ions; Kainic Acid; Kidney; Kinetics; Membrane Potentials; Neuronal Plasticity; Patch-Clamp Techniques; Phenols; Polyamines; Receptors, AMPA; Receptors, Kainic Acid; Spermidine; Spermine | 1998 |
Differing effects of copper,zinc superoxide dismutase overexpression on neurotoxicity elicited by nitric oxide, reactive oxygen species, and excitotoxins.
Topics: Animals; Astrocytes; Cell Death; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Gene Expression Regulation, Enzymologic; Glutamic Acid; Humans; Hydrazines; Kainic Acid; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Penicillamine; Reactive Oxygen Species; Spermine; Superoxide Dismutase; Tyrosine; Vitamin K | 2000 |
Melatonin attenuates the changes in polyamine levels induced by systemic kainate administration in rat brains.
Topics: Animals; Brain; Cerebral Cortex; Chromatography, High Pressure Liquid; Hippocampus; Kainic Acid; Male; Melatonin; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Seizures; Spermidine; Spermine | 2000 |
Radioligand binding assays in the drug discovery process: potential pitfalls of high throughput screenings.
Topics: Animals; Binding, Competitive; Caffeine; Central Nervous System Stimulants; Drug Evaluation, Preclinical; Excitatory Amino Acid Agonists; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kainic Acid; Membranes; Microsomes; Myocardium; Pharmacology; Radioligand Assay; Rats; Rats, Wistar; Ryanodine; Spermine | 2001 |
Huperzine A, a nootropic alkaloid, inhibits N-methyl-D-aspartate-induced current in rat dissociated hippocampal neurons.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Animals; Cells, Cultured; Dithiothreitol; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Hydrogen-Ion Concentration; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neuroprotective Agents; Nootropic Agents; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sesquiterpenes; Spermine; Zinc | 2001 |
Functionally different AMPA-type glutamate receptors in morphologically identified neurons in rat superficial superior colliculus.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Space; In Vitro Techniques; Kainic Acid; Neurons; Rats; Rats, Wistar; Receptors, AMPA; Spermine; Superior Colliculi | 2001 |
GluR2-dependent properties of AMPA receptors determine the selective vulnerability of motor neurons to excitotoxicity.
Topics: Animals; Calcium; Cell Death; Cell Membrane Permeability; Coculture Techniques; Electrophysiology; Kainic Acid; Motor Neurons; Neurotoxins; Rats; Rats, Wistar; Receptors, AMPA; Spermine | 2002 |
Cerebral distribution of polyamines in kainic acid-induced models of status epilepticus and ataxia in rats. Overproduction of putrescine and histological damage.
Topics: Analysis of Variance; Animals; Ataxia; Biogenic Polyamines; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Injections, Intraperitoneal; Injections, Intraventricular; Kainic Acid; Male; Motor Activity; Putrescine; Rats; Rats, Wistar; Spermidine; Spermine; Status Epilepticus | 2002 |
GluR2-free alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors intensify demyelination in experimental autoimmune encephalomyelitis.
Topics: Animals; Animals, Newborn; Brain; Cells, Cultured; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Agents; Female; Gene Expression Regulation; Kainic Acid; Membrane Potentials; Mice; Mice, Knockout; Neuroglia; Patch-Clamp Techniques; Receptors, AMPA; Receptors, Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spermine; Statistics, Nonparametric | 2007 |
Benzodiazepine withdrawal-induced glutamatergic plasticity involves up-regulation of GluR1-containing alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors in Hippocampal CA1 neurons.
Topics: Adaptor Proteins, Signal Transducing; Animals; Benzodiazepines; Cell Membrane; Cytoplasm; Flurazepam; Glutamic Acid; Hippocampus; Kainic Acid; Male; Membrane Potentials; Membrane Proteins; Neuronal Plasticity; Patch-Clamp Techniques; Protein Transport; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spermine; Substance Withdrawal Syndrome; Synapses; Up-Regulation | 2007 |
Synaptic contribution of Ca2+-permeable and Ca2+-impermeable AMPA receptors on isolated carp retinal horizontal cells and their modulation by Zn2+.
Topics: Animals; Calcium; Carps; Cells, Cultured; Dose-Response Relationship, Drug; Glutamic Acid; Kainic Acid; Membrane Potentials; Neurotransmitter Agents; Patch-Clamp Techniques; Pentobarbital; Receptors, AMPA; Retinal Horizontal Cells; Spermine; Synapses; Zinc | 2010 |