spermine has been researched along with cgp 48664 in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (76.47) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Badger, B; Demers, L; Kunselman, S; Manni, A; Rossini, A; Wechter, R | 1 |
| Beltran, PJ; Delworth, MG; Fan, D; Fidler, IJ; Gutman, M; Singh, RK; Wilson, MR | 1 |
| Bergeron, RJ; Ganis, B; Kramer, DL; Porter, CW; Rustum, Y; Wrzosek, C | 1 |
| de Hoog, E; Dorhout, B; Kingma, AW; Muskiet, FA; Odink, MF; van der Veer, E | 1 |
| Hellstrand, P; Nilsson, BO; Swärd, K | 1 |
| Fredlund, JO; Oredsson, SM | 1 |
| Bergeron, RJ; Bernacki, R; Kramer, DL; Mi, Z; Miller, JT; Porter, CW | 1 |
| Beyaert, R; Denecker, T; Penning, LC; Schipper, RG; Vandenabeele, P; Vercammen, D; Verhofstad, AA | 1 |
| de Hoog, E; Dorhout, B; Ferwerda, H; Kingma, AW; Muskiet, FA | 1 |
| de Hoog, E; Dorhout, B; Kingma, AW; Muskiet, FA; Poortenga, PJ | 1 |
| Bergeron, RJ; Black, JD; Kramer, DL; Mett, H; Porter, CW | 1 |
| Alm, K; Berntsson, P; Oredsson, SM | 1 |
| Gomez, M; Hellstrand, P | 1 |
| Alm, K; Berntsson, PS; Kramer, DL; Oredsson, SM; Porter, CW | 1 |
| Borzì, RM; Caldarera, CM; Cetrullo, S; Facchini, A; Flamigni, F; Guarnieri, C; Stanic, I; Stefanelli, C; Tantini, B | 1 |
| Alm, K; Johansson, VM; Oredsson, SM | 1 |
| Blavid, R; Deininger, S; Eschweiler, U; Hauber, J; Hoerauf, A; Kaiser, A; Kusch, P; Sarite, SR; Specht, S | 1 |
17 other study(ies) available for spermine and cgp 48664
| Article | Year |
|---|---|
Biochemical and growth-modulatory effects of the new S-adenosylmethionine decarboxylase inhibitor CGP 48664 in malignant and immortalized normal human breast epithelial cells in culture.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Amidines; Breast; Breast Neoplasms; Cell Division; Cell Line, Transformed; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Indans; Neoplasms, Hormone-Dependent; Ornithine Decarboxylase; Spermidine; Spermine; Tumor Cells, Cultured | 1995 |
Treatment of nude mice with 4-amidinoindan -1- one2 '- amidinohydrazone, a new S-adenosylmethionine decarboxylase inhibitor, delays growth and inhibits metastasis of human melanoma cells.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Cell Division; Culture Media; Dose-Response Relationship, Drug; Humans; Indans; Lung Neoplasms; Male; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Spermidine; Spermine; Tumor Cells, Cultured | 1995 |
Collateral sensitivity of human melanoma multidrug-resistant variants to the polyamine analogue, N1,N11-diethylnorspermine.
Topics: Adenosylmethionine Decarboxylase; Amidines; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Multiple; Eflornithine; Humans; Indans; Melanoma; Ornithine Decarboxylase; Rhodamine 123; Rhodamines; Spermine; Tumor Cells, Cultured | 1994 |
4-Amidinoindan-1-one 2'-amidinohydrazone (CGP 48664A) exerts in vitro growth inhibitory effects that are not only related to S-adenosylmethionine decarboxylase (SAMdc) inhibition.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Antineoplastic Agents; Cell Division; Deoxyadenosines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indans; Leukemia L1210; Mitoguazone; Spermidine; Spermine; Tumor Cells, Cultured | 1997 |
Inhibition of polyamine synthesis influences contractility of intestinal smooth muscle in culture.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Calcium; Cells, Cultured; Enzyme Inhibitors; Female; Guinea Pigs; Ileum; Indans; Kinetics; Muscle Contraction; Muscle, Smooth; Polyamines; Potassium; Putrescine; Spermidine; Spermine | 1997 |
Ordered cell cycle phase perturbations in Chinese hamster ovary cells treated with an S-adenosylmethionine decarboxylase inhibitor.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Cell Cycle; CHO Cells; Cricetinae; DNA; DNA Replication; Enzyme Inhibitors; Indans; Kinetics; Spermine | 1997 |
Human prostatic carcinoma cell lines display altered regulation of polyamine transport in response to polyamine analogs and inhibitors.
Topics: Adenosylmethionine Decarboxylase; Amidines; Biological Transport; Growth Inhibitors; Humans; Indans; Male; Molecular Structure; Polyamines; Prostatic Neoplasms; Spermidine; Spermine; Tumor Cells, Cultured | 1998 |
Sensitization of tnf-induced apoptosis with polyamine synthesis inhibitors in different human and murine tumour cell lines.
Topics: Amidines; Animals; Antineoplastic Agents; Apoptosis; Eflornithine; Enzyme Inhibitors; Fas Ligand Protein; Granulocyte-Macrophage Colony-Stimulating Factor; HeLa Cells; Humans; Indans; Membrane Glycoproteins; Mice; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine; T-Lymphocytes; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
In vivo manipulation of L1210 cell cycle phase distribution with alpha-difluoromethylornithine, 4-amidinoindan-1-one 2'-amidinohydrazone and N1-acetylspermine.
Topics: Amidines; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Eflornithine; Female; Indans; Leukemia L1210; Mice; Mice, Inbred DBA; S Phase; Spermine | 1998 |
In vitro manipulation of L1210 cell cycle kinetics with 4-amidinoindan-1-one 2'-amidinohydrazone, alpha-difluoromethylornithine and N1-acetylspermine.
Topics: Amidines; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Cell Cycle; DNA; Dose-Response Relationship, Drug; Eflornithine; Guanidines; Indans; Leukemia L1210; Mice; Spermine; Tumor Cells, Cultured | 1998 |
Lysosomal sequestration of polyamine analogues in Chinese hamster ovary cells resistant to the S-adenosylmethionine decarboxylase inhibitor, CGP-48664.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Antineoplastic Agents; CHO Cells; Cricetinae; Drug Resistance, Neoplasm; Indans; Lysosomes; RNA, Messenger; Spermine; Vacuoles | 1998 |
Topoisomerase II is nonfunctional in polyamine-depleted cells.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Cell Cycle; Cell Division; CHO Cells; Cricetinae; DNA Damage; DNA Topoisomerases, Type II; Eflornithine; Enzyme Inhibitors; Etoposide; Flow Cytometry; Indans; Ornithine Decarboxylase Inhibitors; Polyamines; Spermine; Topoisomerase II Inhibitors | 1999 |
Endogenous polyamines modulate Ca2+ channel activity in guinea-pig intestinal smooth muscle.
Topics: Amidines; Animals; Calcium Channels, L-Type; Culture Techniques; Enzyme Inhibitors; Female; Guinea Pigs; Ileum; Indans; Muscle, Smooth; Patch-Clamp Techniques; Polyamines; Spermine | 1999 |
Treatment of cells with the polyamine analog N, N11-diethylnorspermine retards S phase progression within one cell cycle.
Topics: Amidines; Animals; Antineoplastic Agents; Biogenic Polyamines; Bromodeoxyuridine; CHO Cells; Cricetinae; DNA; G1 Phase; Indans; S Phase; Spermine | 2000 |
Effect of the polyamine analogue N1,N11-diethylnorspermine on cell survival and susceptibility to apoptosis of human chondrocytes.
Topics: Acetyltransferases; Amidines; Antineoplastic Agents; Apoptosis; Caspases; Cell Line; Cell Survival; Chondrocytes; Cycloheximide; DNA Fragmentation; Eflornithine; Enzyme Activation; Enzyme Inhibitors; Humans; Indans; Ornithine Decarboxylase; Polyamines; Protein Synthesis Inhibitors; Spermine; Tumor Necrosis Factor-alpha | 2008 |
Polyamine depletion with two different polyamine analogues causes DNA damage in human breast cancer cell lines.
Topics: Amidines; Cell Cycle; Cell Line; Cell Line, Tumor; Comet Assay; DNA Damage; Histones; Humans; Indans; Polyamines; Spermine | 2008 |
Down-regulation of hypusine biosynthesis in Plasmodium by inhibition of S-adenosyl-methionine-decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Down-Regulation; Enzyme Inhibitors; Eukaryotic Translation Initiation Factor 5A; Gene Expression Regulation, Enzymologic; Humans; Indans; Kinetics; Malaria, Falciparum; Mice; Mice, Inbred C57BL; Peptide Initiation Factors; Plasmodium falciparum; Protozoan Proteins; Putrescine; RNA-Binding Proteins; Spermidine; Spermine | 2010 |