spermine has been researched along with be 4-4-4-4 in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (88.24) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Basu, HS; Bergeron, CJ; Deen, DF; Feuerstein, BG; Marton, LJ; Pellarin, M | 1 |
| Basu, HS; Contreras, L; Harari, PM; Marton, LJ; Petereit, DG; Pickart, MA | 1 |
| Basu, HS; Deen, DF; Feuerstein, BG; Marton, LJ; Pellarin, M; Smirnov, IV | 1 |
| Igarashi, K; Williams, K | 1 |
| Basu, HS; Casero, RA; Dolan, ME; Feuerstein, BG; Fleig, MJ; Luk, GD; Marton, LJ | 1 |
| Basu, HS; Deen, DF; Feuerstein, BG; Marton, LJ; Pellarin, M; Samejima, K; Shirahata, A | 1 |
| Callery, PS; Eddington, ND; Egorin, MJ; Eiseman, JL; Sentz, DL; Yuan, ZM | 1 |
| Auchter, RM; Harari, PM; Nash, GA; Pickart, MA; Qu, RP | 1 |
| Basu, HS; Jackson, V; Peng, HF; Smirnov, IV; Tiffany, K | 1 |
| Heimbecher, S; Lee, YC; Tabibi, SE; Yalkowsky, SH | 1 |
| Basu, H; Church, D; Jeffers, L; Marton, L; Wilding, G | 1 |
| de Hoog, E; Dorhout, B; Kingma, AW; Muskiet, FA | 1 |
| Dolan, ME; Fleig, MJ; Marton, LJ; Rinker-Schaeffer, CW; Shrivastav, M; Zagaja, GP | 1 |
| Ko, TC; Litvak, DA; Papaconstantinou, HT; Townsend, CM | 1 |
| Basu, HS; Chanbusarakum, L; Dreckschmidt, N; Tu, L | 1 |
| Harris, SP; Marton, LJ; Moss, RL; Patel, JR | 1 |
| Basu, HS; Frydman, B; Marton, LJ; Reddy, VK; Sarkar, A; Valasinas, A | 1 |
17 other study(ies) available for spermine and be 4-4-4-4
| Article | Year |
|---|---|
Two polyamine analogs (BE-4-4-4 and BE-4-4-4-4) directly affect growth, survival, and cell cycle progression in two human brain tumor cell lines.
Topics: Antineoplastic Agents; Brain Neoplasms; Flow Cytometry; Growth Inhibitors; Humans; Spermine; Tumor Cells, Cultured | 1995 |
Slowing proliferation in head and neck tumors: in vitro growth inhibitory effects of the polyamine analog BE-4-4-4-4 in human squamous cell carcinomas.
Topics: Carcinoma, Squamous Cell; Cell Cycle; Cell Division; Drug Screening Assays, Antitumor; Flow Cytometry; Growth Inhibitors; Head and Neck Neoplasms; Humans; Ornithine Decarboxylase Inhibitors; Polyamines; Spermine; Tumor Cells, Cultured | 1995 |
Pretreatment with the polyamine analog 1,19-bis-(ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4) inhibits etoposide cytotoxicity in U-251 MG (NCI) human brain tumor cells.
Topics: Brain Neoplasms; Cell Death; Cell Division; DNA, Neoplasm; Etoposide; Humans; Nuclear Matrix; Spermine; Tumor Cells, Cultured | 1994 |
Antagonist properties of polyamines and bis(ethyl)polyamines at N-methyl-D-aspartate receptors.
Topics: Animals; In Vitro Techniques; Membrane Potentials; Oocytes; Polyamines; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Spermine; Structure-Activity Relationship; Xenopus laevis | 1995 |
Effect of 1,19-bis(ethylamino)-5,10,15-triazanonadecane on human tumor xenografts.
Topics: Animals; Body Weight; Brain Neoplasms; Carmustine; Cell Division; Colonic Neoplasms; Drug Screening Assays, Antitumor; Female; Glioblastoma; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Spermine; Transplantation, Heterologous; Tumor Cells, Cultured | 1994 |
Interaction of a polyamine analogue, 1,19-bis-(ethylamino)-5,10,15- triazanonadecane (BE-4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines.
Topics: Brain Neoplasms; Cell Division; Cell Survival; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1993 |
Plasma pharmacokinetics and urinary excretion of the polyamine analogue 1, 19-bis(ethylamino)-5, 10, 15-triazanonadecane in CD2F1 mice.
Topics: Absorption; Administration, Oral; Animals; Antineoplastic Agents; Blood Proteins; Chromatography, High Pressure Liquid; Female; Half-Life; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Linear Models; Male; Mice; Protein Binding; Specific Pathogen-Free Organisms; Spermine | 1996 |
Growth inhibition of squamous cell carcinoma xenografts with the polyamine analogue BE 4444.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Cell Line; Drug Screening Assays, Antitumor; Female; Growth Inhibitors; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Polyamines; Skin; Spermine | 1996 |
Effects of spermine and its cytotoxic analogs on nucleosome formation on topologically stressed DNA in vitro.
Topics: Animals; Antineoplastic Agents; Cell-Free System; Chickens; DNA Topoisomerases, Type I; DNA, Superhelical; Histones; Nucleosomes; Peptides; Propylamines; Spermine | 1997 |
Derivatization and high-performance liquid chromatographic analysis of pentaazapentacosane pentahydrochloride.
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Dansyl Compounds; Hydrogen-Ion Concentration; Reproducibility of Results; Spermine | 1997 |
Effects of the polyamine analogues BE-4-4-4-4, BE-3-7-3, and BE-3-3-3 on the proliferation of three prostate cancer cell lines.
Topics: Animals; Antineoplastic Agents; Cell Division; Growth Inhibitors; Male; Mice; Mice, Nude; Polyamines; Propylamines; Prostatic Neoplasms; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured | 1997 |
Simultaneous determination of polyamines, N-acetylated polyamines and the polyamine analogues BE-3-3-3 and BE-4-4-4-4 by capillary gas chromatography with nitrogen-phosphorus detection.
Topics: Acetylation; Animals; Chromatography, Gas; Leukemia L1210; Polyamines; Propylamines; Sensitivity and Specificity; Spermine; Tumor Cells, Cultured | 1997 |
Effects of polyamine analogues on prostatic adenocarcinoma cells in vitro and in vivo.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Kidney; Male; Mice; Mice, Nude; Neoplasm Transplantation; Prostatic Neoplasms; Rats; Spermine; Tumor Cells, Cultured | 1998 |
A novel cytotoxic agent for human carcinoid tumors.
Topics: Antineoplastic Agents; Carcinoid Tumor; Cell Division; Drug Screening Assays, Antitumor; Eflornithine; Growth Inhibitors; Humans; Ornithine Decarboxylase; Spermine; Tumor Cells, Cultured | 1998 |
Polyamine analog bis(ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4) enhances simian virus 40 late gene expression.
Topics: Animals; Antineoplastic Agents; Cell Line; Dose-Response Relationship, Drug; Gene Expression Regulation, Viral; Genes, Reporter; Humans; Kinetics; Luciferases; Nucleosomes; Propylamines; Recombinant Proteins; Simian virus 40; Spermine; Transfection; Tumor Cells, Cultured | 1999 |
Polyamines decrease Ca(2+) sensitivity of tension and increase rates of activation in skinned cardiac myocytes.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Magnesium; Myocardial Contraction; Myocardium; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine | 2000 |
cis-Unsaturated analogues of 3,8,13,18,23-pentaazapentacosane (BE-4-4-4-4): synthesis and growth inhibitory effects on human prostate cancer cell lines.
Topics: Antineoplastic Agents; Cell Division; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Male; Prostatic Neoplasms; Spermine; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2001 |