Compounds > spermine

spermine and alpha-synuclein

spermine has been researched along with alpha-synuclein in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's2 (22.22)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Antony, T; Cherny, D; Heim, G; Hoyer, W; Jovin, TM; Subramaniam, V1
Bernstein, SL; Bowers, MT; Dupuis, NF; Grabenauer, M; Gray, HB; Lee, JC; Winkler, JR; Wyttenbach, T1
Loo, JA; Yin, S1
Li, C; Lutz, EA; Pielak, GJ; Ruf, RA; Slade, KM; Wang, GF1
Aprile, FA; Barbut, D; Cascella, R; Cecchi, C; Challa, PK; Chen, SW; Chiti, F; Cohen, SIA; Cremades, N; Dobson, CM; Flagmeier, P; Galvagnion, C; Heller, GT; Kirkegaard, JB; Knowles, TPJ; Kumita, JR; Limbocker, R; Mannini, B; Meisl, G; Nollen, EAA; Perni, M; Vendruscolo, M; Zasloff, M1
Kishore, A; Nandakumar, S; Raj, V; Thekkuveettil, A; Vijayan, B1
Albright, JA; Bigi, A; Cascella, R; Cecchi, C; Chen, SW; Chia, S; Chiti, F; Cremades, N; Dobson, CM; Habchi, J; Kartanas, T; Knowles, TPJ; Kreiser, RP; Kumita, JR; Limbocker, R; Mannini, B; Perni, M; Ruggeri, FS; Vendruscolo, M; Wright, AK; Xu, CK; Zasloff, M1
Baekelandt, V; Lobbestael, E; Martin, S; Si, J; Van den Haute, C; van Veen, S; Vangheluwe, P1
Semenyuk, PI1

Other Studies

9 other study(ies) available for spermine and alpha-synuclein

ArticleYear
Cellular polyamines promote the aggregation of alpha-synuclein.
    The Journal of biological chemistry, 2003, Jan-31, Volume: 278, Issue:5

    Topics: alpha-Synuclein; Binding Sites; Circular Dichroism; Cloning, Molecular; Escherichia coli; Humans; Microscopy, Atomic Force; Microscopy, Electron; Nerve Tissue Proteins; Parkinson Disease; Phosphoproteins; Protein Conformation; Putrescine; Recombinant Proteins; Spectrometry, Fluorescence; Spermidine; Spermine; Synucleins

2003
Spermine binding to Parkinson's protein alpha-synuclein and its disease-related A30P and A53T mutants.
    The journal of physical chemistry. B, 2008, Sep-04, Volume: 112, Issue:35

    Topics: alpha-Synuclein; Mass Spectrometry; Mutant Proteins; Mutation; Parkinson Disease; Protein Binding; Spermine; Time Factors

2008
Mass spectrometry detection and characterization of noncovalent protein complexes.
    Methods in molecular biology (Clifton, N.J.), 2009, Volume: 492

    Topics: alpha-Synuclein; Analytic Sample Preparation Methods; Animals; Fungal Proteins; Humans; Hydrogen-Ion Concentration; Ligands; Myoglobin; Phosphopyruvate Hydratase; Protein Denaturation; Proteins; Spectrometry, Mass, Electrospray Ionization; Spermine

2009
19F NMR studies of alpha-synuclein conformation and fibrillation.
    Biochemistry, 2009, Sep-15, Volume: 48, Issue:36

    Topics: alpha-Synuclein; Buffers; Drug Combinations; Fluorine Radioisotopes; Fluorometry; Humans; Magnetic Resonance Spectroscopy; Molecular Weight; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Sodium Dodecyl Sulfate; Spectrometry, Mass, Electrospray Ionization; Spermine; Tyrosine

2009
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine.
    ACS chemical biology, 2018, 08-17, Volume: 13, Issue:8

    Topics: alpha-Synuclein; Animals; Caenorhabditis elegans; Cell Line; Cholestanes; Disease Models, Animal; Humans; Neurons; Parkinson Disease; Protein Aggregates; Protein Aggregation, Pathological; Spermine

2018
Spermine protects alpha-synuclein expressing dopaminergic neurons from manganese-induced degeneration.
    Cell biology and toxicology, 2019, Volume: 35, Issue:2

    Topics: alpha-Synuclein; Animals; Caenorhabditis elegans; Cell Line; Cell Survival; Diminazene; Dopaminergic Neurons; Humans; Manganese; Nerve Degeneration; Neuroprotective Agents; Spermine

2019
Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism.
    Communications biology, 2020, 08-13, Volume: 3, Issue:1

    Topics: alpha-Synuclein; Amyloid beta-Peptides; Biophysical Phenomena; Carboxyl and Carbamoyl Transferases; Cell Death; Cell Line, Tumor; Cell Membrane; Cholestanes; Escherichia coli Proteins; Humans; Protein Folding; Protein Multimerization; Spermine

2020
ATP13A2 Regulates Cellular α-Synuclein Multimerization, Membrane Association, and Externalization.
    International journal of molecular sciences, 2021, Mar-07, Volume: 22, Issue:5

    Topics: alpha-Synuclein; Cell Line, Tumor; Exocytosis; Humans; Intracellular Membranes; Lysosomes; Mutation; Oxidative Stress; Proteasome Endopeptidase Complex; Protein Multimerization; Proton-Translocating ATPases; Spermine; Ubiquitin

2021
REMD Simulations of Full-Length Alpha-Synuclein Together with Ligands Reveal Binding Region and Effect on Amyloid Conversion.
    International journal of molecular sciences, 2022, Sep-30, Volume: 23, Issue:19

    Topics: alpha-Synuclein; Amyloid; Amyloidogenic Proteins; Amyloidosis; Humans; Intrinsically Disordered Proteins; Ligands; Protein Conformation; Spermine

2022