spermidine has been researched along with n-methylaspartate in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 27 (79.41) | 18.2507 |
| 2000's | 4 (11.76) | 29.6817 |
| 2010's | 2 (5.88) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Benavides, J; Bourdiol, F; Carter, C; Fage, D; Porcella, A; Scatton, B; Voltz, C | 1 |
| Crawley, JN; Evers, JR; Paul, SM | 1 |
| Enomoto, R; Kito, S; Ogita, K; Suzuki, T; Yoneda, Y | 1 |
| Oles, RJ; Singh, L; Vass, CA; Woodruff, GN | 1 |
| Carter, CJ; Lloyd, KG; Scatton, B; Zivkovic, B | 1 |
| Johnson, KM; Sacaan, AI | 1 |
| Aizenman, E; Reynolds, IJ; Rush, EA | 1 |
| Oles, R; Singh, L; Woodruff, G | 1 |
| el-Fakahany, EE; Hu, J; Mahmoud, MI | 1 |
| Belknap, JK; Carter, LA; Crabbe, JC; Janowsky, A | 1 |
| Andou, Y; Enomoto, R; Kataoka, K; Mitani, A; Ogita, K; Yoneda, Y | 1 |
| Carter, C; Fage, D; Nankai, M | 2 |
| D'Souza, SW; McConnell, SE; Slater, P | 1 |
| Iqbal, Z; Siddiqui, F | 1 |
| Carter, C; Fage, D; Nicolas, C | 1 |
| Berrino, L; Filippelli, A; Leyva, J; Maione, S; Pizzirusso, A; Rossi, F; Vitagliano, S | 1 |
| Carter, C; Fage, D; Voltz, C | 2 |
| Abe, K; Chu, PJ; Saito, H; Samejima, K; Shirahata, A | 1 |
| Lewis, SJ; Ohta, H; Talman, WT | 1 |
| Conaty, C; Fahey, JM; Miller, LG; Minocha, SC; Pritchard, GA | 1 |
| Araneda, RC; Bennett, MV; Zukin, RS | 1 |
| Chen, X; Hurlbert, M; Joseph, DB; Kumar, KN; Michaelis, EK; Michaelis, ML | 1 |
| McCoy, L; Richfield, EK | 1 |
| Katsura, M; Ohkuma, S; Shimosato, K; Watanabe, S | 1 |
| Cannavò, L; Ginoprelli, T; Ientile, R; Macaione, S; Pedale, S | 1 |
| Blanchard, J; Gibson, DA; Harris, B; Holley, RC; Littleton, J; Mayer, S; Prendergast, MA | 1 |
| Cebere, A; Cebers, G; Liljequist, S; Wägner, A | 1 |
| Hozumi, S; Kisara, K; Murata, A; Nakagawasai, O; Niijima, F; Tadano, T; Tan-No, K; Yamadera, F | 1 |
| Fu, H; Han, Y; Huang, P; Lee, NT; Li, C; Li, W; Li, ZW; Liu, Y; Luo, J; Pang, Y; Xia, J; Yu, H; Zhang, W | 1 |
| Berry, JN; Butler, TR; Littleton, JM; Mulholland, PJ; Pauly, JR; Prendergast, MA; Self, RL; Sharrett-Field, LJ; Smith, KJ | 1 |
| da Silva Junior, PI; dos Santos, WF; Godoy, LD; Liberato, JL | 1 |
| Fabbrin, S; Girardi, BA; Mello, CF; Rubin, MA; Wendel, AL | 1 |
34 other study(ies) available for spermidine and n-methylaspartate
| Article | Year |
|---|---|
Implication of the polyamines in the neurotoxic effects of N-methyl-D-aspartate.
Topics: Animals; Cell Membrane; Choline O-Acetyltransferase; Corpus Striatum; Dizocilpine Maleate; Glutamate Decarboxylase; Infusions, Parenteral; Isoquinolines; Microinjections; N-Methylaspartate; Neurotoxins; Rats; Receptors, GABA-A; Spermidine; Spermine; Tetrodotoxin | 1992 |
Polyamines inhibit N-methyl-D-aspartate antagonist-induced darting behavior in the rat prefrontal cortex.
Topics: Animals; Behavior, Animal; Frontal Lobe; Injections; Male; Motor Activity; N-Methylaspartate; Piperazines; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine | 1992 |
Identification and characterization of specific binding sites of [3H]spermidine in synaptic membranes of rat brain.
Topics: Animals; Binding Sites; Biogenic Polyamines; Brain Chemistry; Calmodulin; Endopeptidases; Hydrolysis; In Vitro Techniques; Kinetics; Ligands; Male; N-Methylaspartate; Phosphatidylserines; Rats; Rats, Inbred Strains; Spermidine; Synaptic Membranes; Temperature | 1991 |
A slow intravenous infusion of N-methyl-DL-aspartate as a seizure model in the mouse.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Infusions, Intravenous; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Spermidine | 1991 |
Ifenprodil and SL 82.0715 as cerebral antiischemic agents. III. Evidence for antagonistic effects at the polyamine modulatory site within the N-methyl-D-aspartate receptor complex.
Topics: Adrenergic alpha-Antagonists; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Brain; Cells, Cultured; Drug Interactions; Female; Glycine; Male; N-Methylaspartate; Phencyclidine; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine; Spinal Cord | 1990 |
Spermidine reverses arcaine's inhibition of N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release.
Topics: Animals; Biguanides; Binding Sites; Dimethyl Sulfoxide; Hippocampus; Hydrogen-Ion Concentration; Intracellular Fluid; Male; N-Methylaspartate; Norepinephrine; Polyamines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spermidine; Tritium | 1990 |
Reduction of NMDA receptors with dithiothreitol increases [3H]-MK-801 binding and NMDA-induced Ca2+ fluxes.
Topics: Animals; Calcium; Dithionitrobenzoic Acid; Dithiothreitol; Dizocilpine Maleate; Fluorescence; Fura-2; Glutamates; Glycine; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine | 1990 |
In vivo interaction of a polyamine with the NMDA receptor.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Spermidine | 1990 |
Polyamines inhibit nitric oxide synthase in rat cerebellum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cells, Cultured; Cerebellum; Citrulline; Cytosol; Eflornithine; Kinetics; N-Methylaspartate; Neurons; Nitric Oxide Synthase; omega-N-Methylarginine; Polyamines; Putrescine; Rats; Spermidine; Spermine; Tritium | 1994 |
Allosteric regulation of the N-methyl-D-aspartate receptor-linked ion channel complex and effects of ethanol in ethanol-withdrawal seizure-prone and -resistant mice.
Topics: Allosteric Regulation; Animals; Cerebral Cortex; Dizocilpine Maleate; Ethanol; Genetic Predisposition to Disease; Glycine; Hippocampus; Ion Channels; Male; Mice; Mice, Mutant Strains; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures; Spermidine; Substance Withdrawal Syndrome | 1995 |
Binding of [3H]MK-801, NMDA-displaceable [3H]glutamate, [3H]glycine, [3H]spermidine, [3H]kainate and [3H]AMPA to regionally discrete brain membranes of the gerbil: a biochemical study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Cell Membrane; Dizocilpine Maleate; Female; Gerbillinae; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Receptors, Glutamate; Spermidine; Thiocyanates; Tissue Distribution | 1993 |
NMDA receptor subtype selectivity: eliprodil, polyamine spider toxins, dextromethorphan, and desipramine selectively block NMDA-evoked striatal acetylcholine but not spermidine release.
Topics: Acetylcholine; Animals; Corpus Striatum; Desipramine; Dextromethorphan; Indoleacetic Acids; N-Methylaspartate; Phenols; Phenylacetates; Piperidines; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spider Venoms | 1995 |
A polyamine binding site labelled with [3H]spermidine in developing human cerebellum.
Topics: Aged; Analysis of Variance; Autoradiography; Binding Sites; Cerebellum; Child; Child, Preschool; Frozen Sections; Gestational Age; Humans; Infant; Infant, Newborn; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Spermidine; Tissue Preservation; Tritium | 1994 |
Regulation of N-methyl-D-aspartate receptor-mediated calcium transport and norepinephrine release in rat hippocampus synaptosomes by polyamines.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biological Transport; Calcium; Eflornithine; Egtazic Acid; Female; Hippocampus; Kinetics; N-Methylaspartate; Norepinephrine; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Synaptosomes | 1994 |
NMDA receptors with different sensitivities to magnesium and ifenprodil control the release of [14C]acetylcholine and [3H]spermidine from rat striatal slices in vitro.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Aminoquinolines; Animals; Carbon Radioisotopes; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; In Vitro Techniques; Kinetics; Magnesium; Magnesium Chloride; N-Methylaspartate; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Tritium | 1994 |
Effects of the polyamine spermidine on NMDA-induced arterial hypertension in freely moving rats.
Topics: Animals; Biguanides; Blood Pressure; Drug Synergism; Hypertension; Male; Microinjections; N-Methylaspartate; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine | 1994 |
Synergism between the NMDA receptor antagonistic effects of ifenprodil and the glycine antagonist, 7-chlorokynurenate, in vivo.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Synergism; Glycine; Injections; Kynurenic Acid; Male; N-Methylaspartate; Neostriatum; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1994 |
N-(3-aminopropyl)-cyclohexylamine blocks facilitation by spermidine of N-methyl-DL-aspartate-induced seizure in mice in vivo.
Topics: Animals; Cyclohexylamines; Drug Interactions; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Putrescine; Seizures; Serine; Spermidine; Spermine | 1994 |
Spermidine and cardiovascular control in nucleus tractus solitarii in rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Cardiovascular System; Dizocilpine Maleate; Dose-Response Relationship, Drug; Heart Rate; Male; Methylene Blue; Microinjections; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Spermidine | 1993 |
Polyamine potentiation and inhibition of NMDA-mediated increases of intracellular free Ca2+ in cultured chick cortical neurons.
Topics: Animals; Biogenic Polyamines; Calcium; Cells, Cultured; Cerebral Cortex; Chick Embryo; Chromatography, High Pressure Liquid; Fura-2; Ion Transport; N-Methylaspartate; Neurons; Polyamines; Putrescine; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1994 |
Ouabain releases striatal polyamines in vivo independently of N-methyl-D-aspartate receptor activation.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Male; N-Methylaspartate; Ouabain; Piperazines; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1993 |
Effects of polyamines on NMDA-induced currents in rat hippocampal neurons: a whole-cell and single-channel study.
Topics: Action Potentials; Animals; Cells, Cultured; Drug Synergism; Hippocampus; Ion Channel Gating; N-Methylaspartate; Neurons; Rats; Spermidine; Spermine | 1993 |
Striatal NMDA receptor subtypes: the pharmacology of N-methyl-D-aspartate-evoked dopamine, gamma-aminobutyric acid, acetylcholine and spermidine release.
Topics: Animals; Arginine; Corpus Striatum; Dantrolene; Excitatory Amino Acid Antagonists; Glycine Agents; In Vitro Techniques; Muscle Relaxants, Central; N-Methylaspartate; Neurotransmitter Agents; Nitroarginine; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Tetrodotoxin | 1995 |
Ethanol-induced inhibition of [3H]thienylcyclohexylpiperidine (TCP) binding to NMDA receptors in brain synaptic membranes and to a purified protein complex.
Topics: Animals; Brain Chemistry; Dizocilpine Maleate; Dopamine Antagonists; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Haloperidol; Illicit Drugs; Kinetics; Male; Membrane Proteins; N-Methylaspartate; Phencyclidine; Protein Binding; Proteins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sensitivity and Specificity; Spermidine; Synaptic Membranes; Tritium | 1996 |
Washable endogenous substances and regional heterogeneity in agonist enhanced [3H]MK-801 binding in rat brain.
Topics: Animals; Autoradiography; Binding Sites; Brain; Dizocilpine Maleate; Glycine; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Spermidine; Temperature; Therapeutic Irrigation; Time Factors; Tissue Distribution; Tritium | 1996 |
Role of cerebral spermidine in the development of sensitization to convulsant activity of cocaine and lidocaine.
Topics: Animals; Brain Chemistry; Cocaine; Convulsants; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Excitatory Amino Acid Agonists; Injections, Intravenous; Lidocaine; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Putrescine; Seizures; Spermidine | 1997 |
Intracellular polyamine levels are involved in NMDA-evoked nitric oxide production in chick retina cells.
Topics: Animals; Arginine; Cells, Cultured; Chick Embryo; Citrulline; Cyclic GMP; Eflornithine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; N-Methylaspartate; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Polyamines; Receptors, N-Methyl-D-Aspartate; Retina; Spermidine | 1999 |
Acamprosate has no effect on NMDA-induced toxicity but reduces toxicity induced by spermidine or by changing the medium in organotypic hippocampal slice cultures from rat.
Topics: Acamprosate; Animals; Animals, Newborn; Culture Media; Female; Hippocampus; Male; N-Methylaspartate; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Taurine | 2002 |
Spermidine attenuates the inhibitory effect of ethanol on NMDA-induced neurotoxicity.
Topics: Analysis of Variance; Animals; Cell Survival; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; N-Methylaspartate; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spermidine | 2002 |
Effects of NMDA receptor-related agonists on learning and memory impairment in olfactory bulbectomized mice.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Cycloserine; Disease Models, Animal; Dizocilpine Maleate; Drug Therapy, Combination; Injections, Intraventricular; Male; Memory Disorders; Mice; N-Methylaspartate; Olfactory Bulb; Piperidines; Receptors, N-Methyl-D-Aspartate; Spermidine; Time Factors | 2004 |
Novel dimeric bis(7)-tacrine proton-dependently inhibits NMDA-activated currents.
Topics: Allosteric Site; Animals; Cells, Cultured; Dimerization; Hydrogen-Ion Concentration; Ion Channel Gating; N-Methylaspartate; Protons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Tacrine | 2007 |
Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-D-asparate-type glutamate receptors.
Topics: Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Dentate Gyrus; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Piperidines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Valine | 2010 |
Mygalin: a new anticonvulsant polyamine in acute seizure model and neuroethological schedule.
Topics: Acute Disease; Animals; Anticonvulsants; Cognition; Diazepam; Dizocilpine Maleate; Drug Evaluation, Preclinical; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Antagonists; Exploratory Behavior; Locomotion; Male; Maze Learning; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Rotarod Performance Test; Spermidine | 2013 |
Spermidine, a positive modulator of the NMDA receptor, facilitates extinction and prevents the reinstatement of morphine-induced conditioned place preference in mice.
Topics: Animals; Conditioning, Classical; Drug-Seeking Behavior; Extinction, Psychological; Male; Mice; Morphine; Motor Activity; N-Methylaspartate; Opioid-Related Disorders; Receptors, N-Methyl-D-Aspartate; Spermidine | 2020 |