spermidine has been researched along with mitoguazone in 134 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 97 (72.39) | 18.7374 |
| 1990's | 23 (17.16) | 18.2507 |
| 2000's | 13 (9.70) | 29.6817 |
| 2010's | 1 (0.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hori, C; Kano, K; Oka, T; Sakai, T | 1 |
| McCormick, FP; Newton, AA | 1 |
| Linebaugh, BE; Mulder, JA; Rillema, JA | 1 |
| Ahmed, K; Foster, D; Quarfoth, G | 1 |
| Scamans, E; Tyms, AS; Williamson, JD | 1 |
| Henningsson, S; Persson, L; Rosengren, E | 1 |
| Dewey, DL | 1 |
| Nishioka, K; Pargac, MB; Rao, PN; Sunkara, PS | 1 |
| Keir, HM; Melvin, MA | 3 |
| Alhonen-Hongisto, L; Jänne, J; Kallio, A; Pösö, H | 1 |
| Alexandre, H | 1 |
| Lundgren, DW; Oka, T; Sakai, T | 1 |
| Bennett, J; Dave, C; Ehrke, J; Fadale, P; Mihich, E | 1 |
| Brinkley, BR; Nishioka, K; Rao, PN; Sunkara, PS | 1 |
| Paul, D; Rupniak, HT | 1 |
| Hirose, S; Igarashi, K; Kusaka, Y; Nakamura, K; Torii, K | 1 |
| Knutson, JC; Morris, DR | 1 |
| Himberg, JJ; Jänne, J; Pösö, H; Sinervirta, R | 1 |
| Abdel-Monem, MM; Newton, NE | 1 |
| Eriksen, A; Krokan, H | 1 |
| Jorstad, CM; Morris, DR; Seyfried, CE | 1 |
| Gray, JW; Heby, O; Marton, LJ; Wilson, CB | 1 |
| Boynton, AL; Isaacs, RJ; Whitfield, JF | 1 |
| Fillingame, RH; Jorstad, CM; Morris, DR | 1 |
| Oka, T | 1 |
| Jänne, J; Pösö, H; Sinervirta, R | 1 |
| Adachi, K; Inoue, H; Kato, Y; Takeda, Y; Takigawa, M | 1 |
| Clark, JL; Fuller, JL | 1 |
| Brown, DG; Brown, KB; Nelson, NF | 1 |
| Sturman, JA | 1 |
| Rillema, JA | 1 |
| Ask, A; Heby, O; Persson, L | 1 |
| Havouis, R; Khan, NA; Moulinoux, JP; Quemener, V; Wiernsperger, N | 1 |
| Jin, CH; Shinki, T; Suda, T; Takito, J; Tanaka, H | 1 |
| Igarashi, K; Ito, K | 1 |
| Borghgraef, R; De Smedt, H; Geuns, J; Parys, JB; Van Den Bosch, L | 1 |
| Welsh, N | 1 |
| Hirose, S; Igarashi, K; Nagami, R; Ohnishi, R | 1 |
| Dunzendorfer, U; Knöner, M | 1 |
| Kameji, R; Pegg, AE; Rannels, DE; Rannels, SR | 2 |
| Abe, E; Hayashi, T; Jin, CH; Miyaura, C; Shinki, T; Suda, T; Tanaka, H | 1 |
| Igarashi, K; Ito, E; Kashiwagi, K; Sakamaki, Y; Terao, K | 1 |
| Snyder, RD | 1 |
| Autuori, F; Beninati, S; Cocuzzi, ET; Folk, JE; Piacentini, M | 1 |
| Davis, RH; Ristow, JL | 1 |
| Byers, TL; Kameji, R; Pegg, AE; Rannels, DE | 1 |
| Endoh, F; Fujimoto, S; Igarashi, K; Koike, S; Kokubun, M; Ohta, M; Okui, K; Shrestha, RD; Togawa, Y | 1 |
| Bjornsson, TD; Dryjski, M; Korner, G; Kuo, BS | 1 |
| Abe, E; Hayashi, T; Shinki, T; Suda, T; Tanaka, H | 1 |
| Davis, RH; DiGangi, JJ; Krasner, GN; Ristow, JL | 1 |
| Bawa, R; Diwan, JJ; Haley, T; Mannella, CA; Yune, HH | 1 |
| Nuttall, ME; Robinson, FC; Wallace, HM | 1 |
| Dessureault, J; Fleurent, J; Palkonyay, L; Rodrigues, MT; Sircar, S; Weber, JM | 1 |
| Bitonti, AJ; Dumont, JA; McCann, PP | 1 |
| Ailhaud, G; Amri, EZ; Dani, C; Doglio, A; Etienne, J; Grimaldi, P | 1 |
| Erwin, BG; Pegg, AE | 1 |
| Addison, JL; Rannels, DE | 1 |
| Brady, LJ; Brady, PS; Gandour, RD | 1 |
| Alhonen-Hongisto, L; Levin, VA; Marton, LJ | 1 |
| Franzen, MA; Mitchell, JL; Qasba, P; Stofko, RE | 1 |
| Pegg, AE; Shirahata, A | 1 |
| Alhonen-Hongisto, L; Elo, H; Jänne, J; Nikula, P | 1 |
| Addison, JL; Bennett, RA; Rannels, DE | 1 |
| Addison, JL; Pegg, AE; Rannels, DE | 1 |
| Mahan, DW; McCann, PP; Mitchell, JL; Qasba, P | 1 |
| Erwin, BG; Pegg, AE; Persson, L | 1 |
| Addison, JL; Clark, RS; Pegg, AE; Rannels, DE | 1 |
| Jänne, J; Käpyaho, K; Kousa, M; Lauharanta, J; Linnamaa, K; Mustakallio, K | 1 |
| Pledger, WJ; Wharton, W | 1 |
| Jänne, J; Käpyaho, K; Kariniemi, AL; Virtanen, I | 1 |
| Tyms, AS; Williamson, JD | 2 |
| Fuller, DJ; Gerner, EW | 1 |
| Kramer, DL; Porter, CW; Wiseman, A | 1 |
| Jänne, J; Ruohola, H; Seppänen, P | 1 |
| Gordon, AM; Keir, HM; Pearson, CK; Wallace, HM | 1 |
| Jänne, J; Käpyaho, K; Lauharanta, J | 2 |
| Covey, DF; Fair, WR; Heston, WD; Kadmon, D | 1 |
| Alhonen-Hongisto, L; Elo, H; Fagerström, R; Jänne, J; Laine, R | 1 |
| Igarashi, K; Morris, DR | 1 |
| Pegg, AE; Persson, L | 1 |
| Deen, DF; Hung, DT; Marton, LJ; Oredsson, SM; Pegg, AE | 1 |
| Campione, AL; Van Winkle, LJ | 1 |
| Byczkowski, JZ; Porter, CW | 1 |
| Alhonen-Hongisto, L; Jänne, J; Pösö, H; Seppänen, P | 1 |
| Deen, DF; Marton, LJ; Seidenfeld, J | 1 |
| Fozard, JR; Grove, J; Prakash, NJ | 1 |
| Alhonen-Hongisto, L; Jänne, J; Seppänen, P | 2 |
| Erwin, BG; Florini, JR; Pegg, AE; Richman, RA; Stoscheck, CM | 1 |
| Jänne, J; Käpyaho, K; Linnamaa, K | 1 |
| Seppänen, P | 1 |
| Fuller, DJ; Gerner, EW; Herman, TS; Stickney, DG | 1 |
| Hosaka, K; Yamashita, S | 1 |
| Keir, HM; Melvin, MA; Wallace, HM | 1 |
| Hopkins, D; Manchester, KL | 2 |
| Dworaczyk, D; Ganis, B; Porter, CW; Weiser, MM | 1 |
| Gritli-Linde, A; Linde, A; Ruch, JV | 1 |
| Golden, K; Rillema, JA | 1 |
| Barber, MC; Borland, CA; Travers, MT; Vernon, RG | 2 |
| Bucht, E; Larsson, R; Nygren, P; Sjöholm, A; Theodorsson, E | 1 |
| Higaki, I; Kinoshita, H; Matsui-Yuasa, I; Otani, S; Terakura, M | 1 |
| Hyvönen, T; Persson, L; Seiler, N | 1 |
| Schroeder, KK; Snyder, RD | 1 |
| Blachowski, S; Grzelkowska, K; Kasterka, M; Motyl, T; Sysa, P | 1 |
| Hynd, PI; Nancarrow, MJ | 1 |
| Barlier, AM; Benamouzig, R; Tomé, D | 1 |
| Gupta, R; Khurana, N; Rajam, MV; Saxena, RK | 1 |
| de Hoog, E; Dorhout, B; Kingma, AW; Muskiet, FA; Odink, MF; van der Veer, E | 1 |
| Hashimoto, Y; Hibasami, H; Ikemura, N; Imoto, I; Nakao, K; Nakashima, K; Taguchi, Y; Takaji, S | 1 |
| Felschow, DM; Frei, J; Mi, Z; Porter, CW; Stanek, J | 1 |
| Beyaert, R; Denecker, T; Penning, LC; Schipper, RG; Vandenabeele, P; Vercammen, D; Verhofstad, AA | 1 |
| Aslund, L; Grahn, B; Hanke, J; Heby, O; Persson, K | 1 |
| Collins, S; Rillema, JA; Williams, CH | 1 |
| Nada, K; Shen, W; Tachibana, S | 1 |
| Johnson, LR; Ray, RM; Viar, MJ; Yuan, Q | 1 |
| Binderup, L; Ekelund, S; Larsson, R; Nygren, P; Sjöholm, A | 1 |
| Galston, AW; Slocum, RD | 1 |
| Aoki, Y; Ariyoshi, Y; Asai, M; Iwasaki, Y; Morishita, M; Mutsuga, N; Nomura, A; Oiso, Y; Saito, H; Tachikawa, K; Yamamori, E; Yoshida, M | 1 |
| He, L; Kasukabe, Y; Nada, K; Tachibana, S | 1 |
| Fallon, A; Fields, C; Fitzgerald, ME; Johnson, DA; Johnson, LR; Viar, MJ | 1 |
| Couée, I; El Amrani, A; Hennion, F; Hummel, I; Martin-Tanguy, J | 1 |
| Blanco, I; Danchev, N; Dot, J; Rodríguez-Alvarez, J | 1 |
| Krantz, DE; Romero-Calderón, R | 1 |
| Agostinelli, E; Battaglia, V; Brunati, AM; Calheiros, R; Gil, FP; Marques, MP; Toninello, A | 1 |
| Palavan-Unsal, N; Tufekci, MA; Unal, M | 1 |
| Fan, RJ; Hou, MH; Huang, CY; Lu, WJ; Yuann, JM | 1 |
| Cao, Z; Chen, J; Gu, J; Liu, L; Wang, Z; Xu, G; Yang, J; Zhang, H; Zhang, W; Zhou, Q | 1 |
2 review(s) available for spermidine and mitoguazone
| Article | Year |
|---|---|
[Some new aspects of the function of spermidine in animal cells].
Topics: Adenosylmethionine Decarboxylase; Animals; Breast; Cell Division; Chick Embryo; Female; Glucocorticoids; Half-Life; Liver Neoplasms; Male; Milk Proteins; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Prostate; Putrescine; Pyridoxal Phosphate; Rabbits; Rats; RNA; Spermidine; Spermidine Synthase; Spermine | 1975 |
S-adenosylmethionine decarboxylase as target of chemotherapy.
Topics: Adenosylmethionine Decarboxylase; Amine Oxidase (Copper-Containing); Animals; Antineoplastic Agents; Carboxy-Lyases; Carnitine; Cells, Cultured; Gene Amplification; Gene Expression Regulation; Humans; Hydrazones; Mice; Mitochondria; Mitoguazone; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine | 1985 |
132 other study(ies) available for spermidine and mitoguazone
| Article | Year |
|---|---|
Purification and characterization of S-adenosyl-L-methionine decarboxylase from mouse mammary gland and liver.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drug Stability; Female; Immunoassay; Immunodiffusion; Kinetics; Liver; Mammary Glands, Animal; Mice; Mitoguazone; Organ Specificity; Putrescine; Spermidine; Spermine | 1979 |
Polyamine metabolism in cells infected with herpes simplex virus.
Topics: Animals; Cycloheximide; Emetine; L Cells; Mice; Mitoguazone; Polyamines; Putrescine; Simplexvirus; Spermidine; Spermine; Tritium; Viral Plaque Assay; Virus Replication | 1975 |
Regulation of casein synthesis by polyamines in mammary gland explants of mice.
Topics: Animals; Arginine; Caseins; Cyclic AMP; Cyclic GMP; Female; Hydrocortisone; In Vitro Techniques; Insulin; Mammary Glands, Animal; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Phospholipases; Polyamines; Prolactin; Prostaglandins F; Protein Biosynthesis; Putrescine; Spermidine; Spermine; Transcription, Genetic | 1977 |
Effects of polyamines on partial reactions of membrane (Na+ + K+)-ATPase.
Topics: 4-Nitrophenylphosphatase; Adenosine Triphosphate; Animals; Brain; Magnesium; Mitoguazone; Polyamines; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Spermidine; Spermine | 1978 |
Polyamine metabolism in MRC5 cells infected with different herpesviruses.
Topics: Adenosylmethionine Decarboxylase; Carboxy-Lyases; Cell Line; Cell Transformation, Viral; Cytomegalovirus; Fibroblasts; Herpesviridae; Humans; Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines; Spermidine; Spermine; Virus Replication | 1979 |
Polyamine metabolism in the kidneys of castrated and testosterone-treated mice after administration of methylglyoxal bis(guanylhydrazone).
Topics: Animals; Cadaverine; Guanidines; Kidney; Male; Mice; Mitoguazone; Organ Size; Ornithine Decarboxylase; Polyamines; Spermidine; Spermine; Testosterone | 1979 |
Methyl glyoxal bis guanylhydrazone abolition of the toxic action of spermidine on cells in culture.
Topics: Acrolein; Adenosylmethionine Decarboxylase; Animals; Cell Cycle; Cell Division; Cells, Cultured; Guanidines; Mitoguazone; Monoamine Oxidase Inhibitors; Spermidine | 1979 |
Differential effects of inhibition of polyamine biosynthesis on cell cycle traverse and structure of the prematurely condensed chromosomes of normal and transformed cells.
Topics: Animals; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Chromosomes; Cricetinae; DNA Replication; Female; Fibroblasts; HeLa Cells; Humans; Mitoguazone; Ovary; Polyamines; Spermidine; Spermine | 1979 |
Polyamine replacement by magnesium ions in BHK-21/C13 cells.
Topics: Animals; Cations; Cell Division; Cell Line; Cricetinae; Enzyme Induction; Kidney; Magnesium; Mitoguazone; Ornithine Decarboxylase; Polyamines; Spermidine | 1979 |
Conjugated polyamines in BHK-21/C13 cells, and the effect of inhibition of cell growth rate [proceedings].
Topics: Animals; Cell Division; Cell Line; Cricetinae; Guanosine; Kidney; Mitoguazone; Polyamines; Putrescine; Spermidine; Spermine; Thionucleosides | 1979 |
Effect of inhibitors on ornithine and adenosylmethionine decarboxylases on the synthesis of deoxyribonucleic acid in Ehrlich ascites cells in vivo.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Diamines; DNA, Neoplasm; Female; Guanidines; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine; Time Factors | 1979 |
The utilization of an inhibitor of spermidine and spermine synthesis as a tool for the study of the determination of cavitation in the preimplantation mouse embryo.
Topics: Animals; Blastocyst; Cell Count; Cell Division; DNA; Dose-Response Relationship, Drug; Guanidines; Mice; Mitoguazone; RNA; Spermidine; Spermine | 1979 |
Polyamine biosynthesis and DNA synthesis in cultured mammary gland explants from virgin mice.
Topics: Adenosylmethionine Decarboxylase; Animals; DNA; Female; Insulin; Mammary Glands, Animal; Mice; Mitoguazone; Organ Culture Techniques; Ornithine Decarboxylase; Putrescine; Spermidine; Spermidine Synthase; Spermine | 1978 |
Immunosuppressive effects of methylglyoxal-bis(guanylhydrazone) on mouse bone marrow and spleen cells and their antagonism by spermidine.
Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Bone Marrow; Guanidines; Immunosuppressive Agents; Mice; Mice, Inbred C57BL; Mitoguazone; Spermidine; Spleen; Time Factors | 1978 |
Role of polyamines in cytokinesis of mammalian cells.
Topics: Cell Division; Cell Line; Cytoskeleton; Mitoguazone; Ornithine; Putrescine; Spermidine; Spermine | 1979 |
Inhibition of spermidine and spermine synthesis leads to growth arrest of rat embryo fibroblasts in G1.
Topics: Adenosylmethionine Decarboxylase; Cell Cycle; Cell Division; Cell Line; DNA; Mitoguazone; Putrescine; Spermidine; Spermine | 1978 |
Relationship between polyamine contents and protease activity in the rat submaxillary gland.
Topics: Adenosylmethionine Decarboxylase; Animals; Male; Mitoguazone; Ornithine Decarboxylase; Peptide Hydrolases; Polyamines; Putrescine; Rats; Spermidine; Spermine; Submandibular Gland; Testis; Testosterone | 1978 |
Diminished excretion of polyamines from BHK-21/C13 cells exposed to methylglyoxal bis(guanylhydrazone).
Topics: Cell Division; Cell Line; Guanidines; Mitoguazone; Polyamines; Putrescine; Spermidine; Spermine | 1978 |
Cellular polyamine depletion reduces DNA synthesis in isolated lymphocyte nuclei.
Topics: Animals; Cattle; Cell Nucleus; DNA; DNA Replication; Guanidines; Kinetics; Lymphocytes; Mitoguazone; Ornithine; Putrescine; Spermidine; Spermine | 1978 |
Putrescine-insensitive S-adenosyl-L-methionine decarboxylase from Tetrahymena pyriformis.
Topics: Adenosylmethionine Decarboxylase; Brocresine; Carboxy-Lyases; Escherichia coli; Liver; Mitoguazone; Putrescine; S-Adenosylmethionine; Saccharomyces cerevisiae; Spermidine; Tetrahymena pyriformis | 1975 |
Inhibitors of polyamine biosynthesis. 4. Effects of alpha-methyl-(+/-)-ornithine and methylglyoxal bis(guanylhydrazone) on growth and polyamine content of L1210 leukemic cells of mice.
Topics: Animals; Cell Division; Cells, Cultured; DNA, Neoplasm; Guanidines; Leukemia L1210; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
DNA synthesis in HeLa cells and isolated nuclei after treatment with an inhibitor of spermidine synthesis, methyl glyoxal bis(guanylhydrazone).
Topics: Cell Nucleus; DNA Replication; Guanidines; HeLa Cells; Kinetics; Mitoguazone; Protein Biosynthesis; Putrescine; Spermidine; Spermine | 1977 |
Inhibition of the synthesis of polyamines and DNA in activated lymphocytes by a combination of alpha-methylornithine and methylglyoxal bis(guanylhydrazone).
Topics: Animals; Cattle; Cell Division; Concanavalin A; DNA; DNA Replication; Drug Interactions; Guanidines; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Mitoguazone; Ornithine; Polyamines; Protein Biosynthesis; Putrescine; RNA; Spermidine; Spermine | 1977 |
Effect of methylglyoxal-bis (guanylhydrazone), an inhibitor of spermidine and spermine synthesis, on cell cycle traverse.
Topics: Animals; Brain Neoplasms; Cell Cycle; Cells, Cultured; Guanidines; Mitoguazone; Putrescine; Rats; Spermidine; Spermine | 1977 |
A possible involvement polyamines in the initiation of DNA synthesis by human WI-38 and mouse BALB/3T3 cells.
Topics: Cell Line; DNA; Guanidines; Mitoguazone; Polyamines; Putrescine; RNA; Spermidine; Spermine | 1976 |
Increased cellular levels of spermidine or spermine are required for optimal DNA synthesis in lymphocytes activated by concanavalin A.
Topics: Animals; Cattle; Cell Division; Concanavalin A; DNA; Lymphocyte Activation; Lymphocytes; Mitoguazone; Mitosis; Spermidine; Spermine | 1975 |
S-adenosylmethionine decarboxylase from baker's yeast.
Topics: Adenosylmethionine Decarboxylase; Benzylamines; Borohydrides; Carboxy-Lyases; Chromatography, Affinity; Cyanides; Diamines; Isoniazid; Mitoguazone; Putrescine; Pyridoxal Phosphate; Saccharomyces cerevisiae; Semicarbazides; Sepharose; Spermidine; Spermidine Synthase | 1975 |
Effect of DL-alpha-hydrazino-delta-aminovaleric acid, an inhibitor of ornithine decarboxylase, on polyamine metabolism in isoproterenol-stimulated mouse parotid glands.
Topics: Adenosylmethionine Decarboxylase; Animals; Binding, Competitive; Carboxy-Lyases; DNA; Hydrazines; In Vitro Techniques; Isoproterenol; Male; Mice; Mitoguazone; Mitosis; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Parotid Gland; Polyamines; Putrescine; RNA; Spermidine; Spermine; Stimulation, Chemical; Valine | 1975 |
Regulation of ornithine decarboxylase in 3T3 cells by putrescine and spermidine: indirect evidence for translational control.
Topics: Camptothecin; Carboxy-Lyases; Cells, Cultured; Enzyme Induction; Mitoguazone; Ornithine Decarboxylase; Protein Biosynthesis; Putrescine; Spermidine; Trichodermin | 1975 |
Effects of polyamines and methylglyoxal bis(guanylhydrazone) on hepatic nuclear structure and deoxyribonucleic acid template activity.
Topics: Animals; Cattle; Cell Nucleus; DNA; DNA Nucleotidyltransferases; Guanidines; Histones; In Vitro Techniques; Liver; Male; Microscopy, Electron; Mitoguazone; Nucleic Acid Denaturation; Polyamines; Putrescine; Rats; Spermidine; Spermine; Templates, Genetic; Thymus Gland | 1975 |
Effect of methylglyoxal bis (guanylhydrazone) (MGBG) in vivo on the decarboxylation of s-adenosylmethionine and synthesis of spermidine in the rat and guinea pig.
Topics: Adenosylmethionine Decarboxylase; Animals; Brain; Carboxy-Lyases; Guanidines; Guinea Pigs; Kidney; Liver; Male; Mitoguazone; Rats; Spermidine; Time Factors | 1976 |
Activation of casein synthesis by prostaglandins plus spermidine in mammary gland explants of mice.
Topics: Animals; Arachidonic Acids; Caseins; Female; Mammary Glands, Animal; Mice; Mitoguazone; Prolactin; Prostaglandins; Prostaglandins E; Prostaglandins F; Spermidine | 1976 |
Increased survival of L1210 leukemic mice by prevention of the utilization of extracellular polyamines. Studies using a polyamine-uptake mutant, antibiotics and a polyamine-deficient diet.
Topics: Animals; Anti-Bacterial Agents; Biological Transport; Carbon Radioisotopes; Drug Resistance; Eflornithine; Extracellular Space; Female; Leukemia L1210; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mitoguazone; Mutation; Polyamines; Sex Factors; Spermidine; Spermine; Tritium | 1992 |
Characterization of metformin transport system in NIH 3T3 cells.
Topics: 3T3 Cells; Amino Acids; Animals; Biological Transport; Extracellular Space; Ionophores; Metformin; Mice; Mitoguazone; Mutation; Polyamines; Sodium; Spermidine; Time Factors | 1992 |
Transglutaminase is involved in the fusion of mouse alveolar macrophages induced by 1 alpha, 25-dihydroxyvitamin D3.
Topics: Animals; Calcitriol; Cell Fusion; Cystamine; Enzyme Induction; Interleukin-4; Macrophages; Male; Mice; Mitoguazone; Pulmonary Alveoli; Spermidine; Transglutaminases | 1991 |
Polyamine regulation of the synthesis of thymidine kinase in bovine lymphocytes.
Topics: Adenosylmethionine Decarboxylase; Animals; Base Sequence; Cattle; Cells, Cultured; Concanavalin A; Cycloheximide; DNA Polymerase II; DNA Probes; DNA Replication; Eflornithine; Kinetics; Lymphocyte Activation; Lymphocytes; Mitoguazone; Molecular Sequence Data; Polyamines; Polyribosomes; RNA, Messenger; Spermidine; Thymidine Kinase; Thymidylate Synthase; Transcription, Genetic | 1990 |
Regulation of the Na(+)-dependent and the Na(+)-independent polyamine transporters in renal epithelial cells (LLC-PK1).
Topics: Animals; Biological Transport; Carrier Proteins; Cell Line; Cell Membrane; Cells, Cultured; Chromatography, High Pressure Liquid; Cycloheximide; Dactinomycin; Eflornithine; Epithelial Cells; Epithelium; Kidney; Mitoguazone; Polyamines; Putrescine; Serum Albumin, Bovine; Sodium; Spermidine; Spermine; Swine | 1990 |
A role for polyamines in glucose-stimulated insulin-gene expression.
Topics: Animals; Cell Nucleus; Culture Techniques; Cycloheximide; Dactinomycin; Eflornithine; Gene Expression; Glucose; Insulin; Islets of Langerhans; Male; Mice; Mitoguazone; Polyamines; RNA, Messenger; Spermidine; Spermine | 1990 |
Methylglyoxal bis(guanylhydrazone) elimination of polyamine effects on protein synthesis.
Topics: Animals; Cell-Free System; DNA; Escherichia coli; Kinetics; Mitoguazone; Peptides; Poly U; Proteins; Rabbits; RNA; RNA-Dependent RNA Polymerase; RNA, Ribosomal; Spermidine; Spermine | 1985 |
[Therapy with inhibitors of polyamine biosynthesis in refractory prostatic carcinoma. An experimental and clinical study].
Topics: Adenocarcinoma; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Carboxy-Lyases; Carcinoma; Eflornithine; Estrogens; Humans; Male; Mitoguazone; Neoplasm Metastasis; Ornithine; Ornithine Decarboxylase Inhibitors; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatitis; Putrescine; Rats; Spermidine; Spermine | 1985 |
Spermidine uptake by type II pulmonary epithelial cells in primary culture.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Blood; Calcimycin; Cells, Cultured; Epithelium; Gramicidin; Kinetics; Lung; Male; Mitoguazone; Paraquat; Putrescine; Rats; Rats, Inbred Strains; Sodium; Spermidine; Spermine; Temperature | 1989 |
Spermidine-dependent proteins are involved in the fusion of mouse alveolar macrophages induced by 1 alpha,25-dihydroxyvitamin D3 and interleukin 4.
Topics: Animals; Calcitriol; Cell Fusion; Interferon-gamma; Interleukin-4; Interleukins; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice; Mitoguazone; Protein Biosynthesis; Proteins; Spermidine; Tretinoin | 1989 |
Swelling of the Golgi apparatus and decrease of galactosyltransferase in polyamine-deficient bovine lymphocytes and epithelium of mouse small intestine.
Topics: Animals; Cattle; Cells, Cultured; Concanavalin A; Eflornithine; Epithelium; Galactosyltransferases; Golgi Apparatus; Intestinal Mucosa; Intestine, Small; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Microscopy, Electron; Mitoguazone; Polyamines; Spermidine; Spermine | 1989 |
Inhibition of X-ray-induced DNA strand break repair in polyamine-depleted HeLa cells.
Topics: DNA Repair; DNA, Neoplasm; Eflornithine; HeLa Cells; Humans; Mitoguazone; Polyamines; Putrescine; Spermidine; Spermine | 1989 |
Spermidine uptake by type II pneumocytes: interactions of amine uptake pathways.
Topics: Animals; Biological Transport; Cells, Cultured; Choline; DNA; Epithelial Cells; Epithelium; Kinetics; Lithium; Lung; Male; Mitoguazone; Paraquat; Putrescine; Rats; Rats, Inbred Strains; Sodium; Spermidine; Spermine; Time Factors | 1989 |
Covalent incorporation of polyamines as gamma-glutamyl derivatives into CHO cell protein.
Topics: Animals; Cell Division; Cell Line; Cricetinae; Cricetulus; Eflornithine; Female; Mitoguazone; Ovary; Polyamines; Proteins; Putrescine; Spermidine; Spermine; Transglutaminases | 1988 |
Polyamine transport in Neurospora crassa.
Topics: Biological Transport; Cations; Hydrogen-Ion Concentration; Kinetics; Mitoguazone; Neurospora; Neurospora crassa; Polyamines; Potassium Chloride; Putrescine; Spermidine; Spermine | 1988 |
Multiple pathways for uptake of paraquat, methylglyoxal bis(guanylhydrazone), and polyamines.
Topics: Aminoisobutyric Acids; Animals; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Eflornithine; Female; Mitoguazone; Ovary; Paraquat; Polyamines; Putrescine; Spermidine; Spermine | 1987 |
Enhanced antitumor efficacy with a combination of hyperthermochemotherapy and thermosensitization with polyamine antimetabolites in nude mice.
Topics: Animals; Antimetabolites, Antineoplastic; DNA, Neoplasm; Eflornithine; Hyperthermia, Induced; Mice; Mice, Inbred BALB C; Mice, Nude; Mitoguazone; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Polyamines; Putrescine; Spermidine; Spermine; Stomach Neoplasms; Time Factors | 1987 |
Role of polyamines in the stimulation of synthesis and secretion of plasminogen activator from bovine aortic endothelial cells.
Topics: Animals; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Eflornithine; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Glycoproteins; Mitoguazone; Plasminogen Activators; Plasminogen Inactivators; Polyamines; Putrescine; Spermidine; Spermine | 1988 |
Polyamines are involved in the 1-alpha,25-dihydroxyvitamin D3-induced fusion of mouse alveolar macrophages.
Topics: Animals; Calcitriol; Cell Fusion; Cells, Cultured; Eflornithine; Macrophages; Male; Mice; Mitoguazone; Polyamines; Protein Biosynthesis; Pulmonary Alveoli; Spermidine; Spermine | 1986 |
Distinct roles of putrescine and spermidine in the regulation of ornithine decarboxylase in Neurospora crassa.
Topics: Cyclohexylamines; Gene Expression Regulation; Mitoguazone; Neurospora; Neurospora crassa; Ornithine Decarboxylase; Putrescine; Spermidine | 1985 |
Enhanced uptake of spermidine and methylglyoxal-bis(guanylhydrazone) by rat liver mitochondria following outer membrane lysis.
Topics: Animals; Antimycin A; Digitonin; Intracellular Membranes; Magnesium; Mitochondria, Liver; Mitoguazone; Permeability; Potassium; Rats; Spermidine | 1988 |
Acetylation of spermidine and methylglyoxal bis(guanylhydrazone) in baby-hamster kidney cells (BHK-21/C13).
Topics: Acetylation; Acetyltransferases; Animals; Cell Nucleus; Cells, Cultured; Chromatography, High Pressure Liquid; Cricetinae; Cytosol; Half-Life; Kidney; Mitoguazone; Putrescine; Spermidine; Spermine | 1988 |
Isolation and uptake characteristics of adenovirus transformed cell revertants resistant to the antiproliferative effects of methylglyoxal bis(guanylhydrazone).
Topics: Adenosylmethionine Decarboxylase; Adenoviridae; Animals; Brain; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Drug Resistance; Mice; Mice, Nude; Mitoguazone; Mutation; Neoplasm Transplantation; Rats; Spermidine | 1987 |
Characterization of Trypanosoma brucei brucei S-adenosyl-L-methionine decarboxylase and its inhibition by Berenil, pentamidine and methylglyoxal bis(guanylhydrazone).
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Carboxy-Lyases; Diminazene; Male; Mitoguazone; Pentamidine; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Trypanocidal Agents; Trypanosoma brucei brucei | 1986 |
Adipose cell differentiation: evidence for a two-step process in the polyamine-dependent Ob1754 clonal line.
Topics: Adipose Tissue; Cell Differentiation; Cell Line; Clone Cells; DNA; Glycerolphosphate Dehydrogenase; Lipoprotein Lipase; Mitoguazone; Putrescine; RNA, Messenger; Spermidine | 1986 |
Regulation of spermidine/spermine N1-acetyltransferase in L6 cells by polyamines and related compounds.
Topics: Acetyltransferases; Cells, Cultured; Enzyme Induction; Mitoguazone; Polyamines; Spermidine; Spermine | 1986 |
Uptake of exogenous spermidine by rat lungs perfused in situ.
Topics: Animals; Biological Transport; Kinetics; Lung; Male; Mitoguazone; Perfusion; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1987 |
Effect of methylglyoxal bis(guanylhydrazone) on hepatic, heart and skeletal muscle mitochondrial carnitine palmitoyltransferase and beta-oxidation of fatty acids.
Topics: Acyltransferases; Animals; Binding, Competitive; Carnitine; Carnitine O-Palmitoyltransferase; Diphenylhexatriene; Fatty Acids; Female; Fluorescence Polarization; Intracellular Membranes; Kinetics; Male; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Mitoguazone; Muscles; Oxidation-Reduction; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1987 |
Modification of uptake and antiproliferative effect of methylglyoxal bis(guanylhydrazone) by treatment with alpha-difluoromethylornithine in rodent cell lines with different sensitivities to methylglyoxal bis(guanylhydrazone).
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Eflornithine; Guanidines; Kinetics; Mitochondria; Mitoguazone; Ornithine; Putrescine; Pyruvates; Pyruvic Acid; Rats; Spermidine; Temperature; Time Factors | 1985 |
Ornithine decarboxylase modification and polyamine-stimulated enzyme inactivation in HTC cells.
Topics: Animals; Cell Line; Chromatography, Gel; Chromatography, Ion Exchange; Cycloheximide; Eflornithine; Isoenzymes; Mitoguazone; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Rats; Spermidine | 1985 |
Regulation of S-adenosylmethionine decarboxylase activity in rat liver and prostate.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cycloheximide; Eflornithine; Half-Life; Immunosorbent Techniques; Kinetics; Liver; Male; Mitoguazone; Molecular Weight; Ornithine; Prostate; Putrescine; Rabbits; Radioimmunoassay; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1985 |
Increased pulmonary uptake of exogenous polyamines after unilateral pneumonectomy.
Topics: Adrenalectomy; Animals; Kinetics; Lung; Male; Mitoguazone; Perfusion; Pneumonectomy; Polyamines; Pulmonary Circulation; Rats; Rats, Inbred Strains; Spermidine; Time Factors | 1986 |
Carrier-mediated uptake of methylglyoxal bis(guanylhydrazone) by rat lungs perfused in situ.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Guanidines; Kinetics; Lung; Male; Mitoguazone; Perfusion; Pulmonary Circulation; Putrescine; Rats; Rats, Inbred Strains; Serotonin; Spermidine; Spermine; Time Factors | 1985 |
Dicyclohexylamine effects on HTC cell polyamine content and ornithine decarboxylase activity.
Topics: Animals; Cell Division; Cells, Cultured; Cyclohexylamines; Liver Neoplasms, Experimental; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1985 |
Induction of spermidine/spermine N1-acetyltransferase by methylglyoxal bis(guanylhydrazone).
Topics: Acetyltransferases; Animals; Enzyme Induction; Female; Kidney; Kinetics; Liver; Mitoguazone; Organ Specificity; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Spleen | 1985 |
Interaction of paraquat and amine uptake by rat lungs perfused in situ.
Topics: Animals; Drug Interactions; Kinetics; Lung; Male; Mitoguazone; Paraquat; Perfusion; Rats; Spermidine | 1985 |
Methylglyoxal BIS (guanylhydrazone) and alpha-difluoromethylornithine-induced polyamine deprivation in psoriatic lesions.
Topics: Carboxy-Lyases; Dose-Response Relationship, Drug; Eflornithine; Guanidines; Humans; Injections, Intradermal; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Psoriasis; Putrescine; Skin; Spermidine; Spermine | 1982 |
Macromolecular synthesis and stability in growth-arrested BALB/c-3T3 cells.
Topics: Animals; Cell Cycle; Cells, Cultured; Dactinomycin; Interphase; Mice; Mitoguazone; Polyamines; RNA; Spermidine; Spermine; Time Factors | 1982 |
Effect of polyamine antimetabolites on cultured human keratinocytes from normal and uninvolved psoriatic skin.
Topics: Antimetabolites; Cell Division; Cells, Cultured; DNA; Eflornithine; Guanidines; Humans; Keratins; Mitoguazone; Ornithine; Protein Biosynthesis; Psoriasis; Putrescine; Skin; Spermidine; Spermine | 1984 |
Polyamine metabolism in MRC-5 cells infected with human cytomegalovirus.
Topics: Biological Transport; Cell Line; Cytomegalovirus; DNA, Viral; Humans; Kinetics; Mitoguazone; Putrescine; Spermidine; Spermine; Time Factors | 1980 |
Inhibitors of polyamine biosynthesis block human cytomegalovirus replication.
Topics: Antiviral Agents; Cells, Cultured; Cytomegalovirus; Eflornithine; Guanidines; Humans; Mitoguazone; Ornithine; Polyamines; Spermidine; Spermine; Virus Replication | 1982 |
Sensitization to heat by the polyamines and their analogs.
Topics: Amifostine; Animals; Cadaverine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Diamines; Dose-Response Relationship, Drug; Hot Temperature; Mitoguazone; Polyamines; Putrescine; Spermidine | 1983 |
Isolation and uptake characteristics of human cell variants resistant to the antiproliferative effects of methylglyoxal bis(guanylhydrazone).
Topics: Biological Transport; Cell Cycle; Cell Line; Cell Transformation, Viral; Drug Resistance; Genetic Variation; Guanidines; Humans; Kinetics; Lung; Mitoguazone; Simian virus 40; Spermidine; Thioguanine | 1983 |
Ethylglyoxal bis(guanylhydrazone) as an inhibitor of polyamine biosynthesis in L1210 leukemia cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Guanidines; Leukemia L1210; Microscopy, Electron; Mitochondria; Mitoguazone; Polyamines; Receptors, Cell Surface; Spermidine; Spermine | 1984 |
Activation of ADP-ribosyltransferase in polyamine-depleted mammalian cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cells, Cultured; Centrifugation, Density Gradient; Chromatography; Cricetinae; DNA; Enzyme Activation; Fibroblasts; Kidney; Mitoguazone; Nucleotidyltransferases; Ornithine; Poly(ADP-ribose) Polymerases; Spermidine; Spermine | 1984 |
Inhibition of DNA and protein synthesis in UV-irradiated mouse skin by 2-difluoromethylornithine, methylglyoxal bis(guanylhydrazone), and their combination.
Topics: Animals; DNA Replication; Drug Interactions; Eflornithine; Female; Guanidines; Mice; Mitoguazone; Ornithine; Protein Biosynthesis; Putrescine; Skin; Spermidine; Ultraviolet Rays | 1983 |
Differential effect of alpha-difluoromethylornithine on the in vivo uptake of 14C-labeled polyamines and methylglyoxal bis(guanylhydrazone) by a rat prostate-derived tumor.
Topics: Animals; Antineoplastic Agents; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Eflornithine; Guanidines; Male; Mitoguazone; Ornithine; Polyamines; Prostatic Neoplasms; Putrescine; Rats; Rats, Inbred Strains; Spermidine | 1984 |
Different efflux rates may determine the cellular accumulation of various bis(guanylhydrazones).
Topics: Animals; Cells, Cultured; Eflornithine; Guanidines; Leukemia L1210; Mice; Mitoguazone; Ornithine; Spermidine; Time Factors | 1984 |
Physiological effects in bovine lymphocytes of inhibiting polyamine synthesis with ethylglyoxal bis(guanylhydrazone).
Topics: Animals; Aphidicolin; Cattle; Cycloheximide; Diterpenes; DNA Replication; Eflornithine; Guanidines; Kinetics; Lymphocytes; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Protein Biosynthesis; Proteins; Spermidine | 1984 |
Studies of the induction of spermidine/spermine N1-acetyltransferase using a specific antiserum.
Topics: Acetyltransferases; Animals; Brain; Carbon Tetrachloride; Enzyme Induction; Immune Sera; Intestines; Kidney; Liver; Lung; Male; Mice; Mitoguazone; Organ Specificity; Pancreas; Prostate; Rats; Spermidine; Thioacetamide | 1984 |
Potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity in 9L rat brain tumor cells by methylglyoxal-bis(guanylhydrazone), an inhibitor of S-adenosyl-L-methionine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Animals; Brain Neoplasms; Carboxy-Lyases; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Guanidines; Mitoguazone; Putrescine; Rats; Spermidine; Spermine | 1984 |
Periimplantation-like growth and development of mouse blastocysts in medium containing horse serum.
Topics: Animals; Blastocyst; Blood; Cattle; Culture Media; Embryo Implantation; Female; Fetal Blood; Horses; Mice; Mice, Inbred ICR; Mitoguazone; Ornithine; Polyamines; Spermidine; Spermine | 1984 |
Interactions between bis(guanylhydrazones) and polyamines in isolated mitochondria.
Topics: Animals; Antineoplastic Agents; Carbanilides; Dinitrophenols; Drug Interactions; Guanidines; In Vitro Techniques; Intracellular Membranes; Leukemia L1210; Liver Neoplasms, Experimental; Mitochondria; Mitochondria, Liver; Mitoguazone; Oxygen Consumption; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1983 |
Sensitive enzymic determination of methylglyoxal bis(guanylhydrazone) in cultured cells and in animal tissues.
Topics: Adenosylmethionine Decarboxylase; Amine Oxidase (Copper-Containing); Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Guanidines; Humans; Kidney; Kinetics; Leukemia, Lymphoid; Liver; Methods; Mice; Mitoguazone; Putrescine; Rats; Spermidine; Spermine; Spleen | 1980 |
Depletion of intracellular polyamine content does not alter the survival of 9L rat brain tumour cells after X-irradiation.
Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Cells, Cultured; DNA; DNA, Neoplasm; Eflornithine; Guanidines; Mitoguazone; Ornithine; Polyamines; Putrescine; Radiation Tolerance; Rats; Spermidine; Spermine; X-Rays | 1980 |
Ovarian function in the rat following irreversible inhibition of L-ornithine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Eflornithine; Estrus; Female; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Ovary; Ovulation; Pregnancy; Putrescine; Rats; Spermidine; Spermine | 1980 |
Intracellular putrescine and spermidine deprivation induces increased uptake of the natural polyamines and methylglyoxal bis(guanylhydrazone).
Topics: Adenosylmethionine Decarboxylase; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Eflornithine; Guanidines; Mitoguazone; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine | 1980 |
Effects of inhibitors of ornithine and S-adenosylmethionine decarboxylases on L6 myoblast proliferation.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Cells, Cultured; Eflornithine; Mitoguazone; Muscles; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1982 |
Effect of epidermal polyamine depletion on the accumulation of methylglyoxal bis(guanylhydrazone) in mouse skin.
Topics: Animals; Eflornithine; Female; Guanidines; Mice; Mitoguazone; Ornithine; Polyamines; Putrescine; Skin; Skin Physiological Phenomena; Spermidine | 1982 |
Some properties of the polyamine deprivation-inducible uptake system for methylglyoxal bis(guanylhydrazone) in tumor cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Eflornithine; Guanidines; Iodoacetates; Iodoacetic Acid; Mice; Mitoguazone; Neoplasms, Experimental; Ornithine; Ouabain; Polyamines; Putrescine; Spermidine | 1981 |
Combined topical use of difluoromethyl ornithine and methylglyoxal bis (guanylhydrazone) in UV-irradiated mouse skin.
Topics: Adenosylmethionine Decarboxylase; Animals; Eflornithine; Female; Guanidines; Male; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Skin; Spermidine; Ultraviolet Rays | 1982 |
Polyamines and polyamine biosynthesis in cells exposed to hyperthermia.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Guanidines; Hot Temperature; Mitoguazone; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Time Factors | 1983 |
Induction of choline transport and its role in the stimulation of the incorporation of choline into phosphatidylcholine by polyamines in a polyamine auxotroph of Saccharomyces cerevisiae.
Topics: Biological Transport; Choline; Kinetics; Mitoguazone; Phosphatidylcholines; Polyamines; Putrescine; Saccharomyces cerevisiae; Spermidine; Spermine | 1981 |
Conjugation of polyamines in mammalian cells in culture.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cricetinae; Embryo, Mammalian; Guanosine; Kidney; Kinetics; Mice; Mitoguazone; Polyamines; Putrescine; Spermidine; Spermine; Thionucleosides | 1980 |
The influence of nerve section on the metabolism of polyamines in rat diaphragm muscle.
Topics: Adenosylmethionine Decarboxylase; Animals; Diaphragm; Female; Hypertrophy; In Vitro Techniques; Male; Mitoguazone; Muscle Denervation; Muscles; Ornithine Decarboxylase; Polyamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Spermidine | 1981 |
Control of activity of S-adenosylmethionine decarboxylase in muscle by spermidine.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Dactinomycin; Diaphragm; Mitoguazone; Muscles; Putrescine; Rats; Spermidine | 1980 |
Polyamines and biosynthetic enzymes in the rat intestinal mucosa and the influence of methylglyoxal-bis(guanylhydrazone).
Topics: Adenosylmethionine Decarboxylase; Alkaline Phosphatase; Animals; Cell Separation; Guanidines; Intestinal Mucosa; Mitoguazone; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Spermidine; Spermine; Sucrase | 1980 |
Relation of the antiproliferative action of methylglyoxal-bis(guanylhydrazone) to the natural polyamines.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Female; Guanidines; Humans; Magnesium; Mice; Mitoguazone; Spermidine; Spermine | 1980 |
Polyamine depletion-mediated effects on murine odontogenesis are dependent on tooth developmental stage and culture conditions.
Topics: Animals; Cell Differentiation; Cell Division; Culture Media; DNA; Eflornithine; Guanidines; Mice; Mitoguazone; Odontoblasts; Odontogenesis; Organ Culture Techniques; Polyamines; Putrescine; Spermidine; Time Factors; Tooth | 1995 |
Studies on the mechanism by which prolactin stimulates alpha-aminoisobutyric acid uptake into cultured mouse mammary tissues.
Topics: 1-Methyl-3-isobutylxanthine; Aminoisobutyric Acids; Animals; Biogenic Polyamines; Bucladesine; Cells, Cultured; Eflornithine; Enzyme Activation; Female; Indomethacin; Mammary Glands, Animal; Mice; Mitoguazone; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Prolactin; Prostaglandins; Protein Kinase C; Spermidine | 1993 |
Growth hormone inhibition of lipogenesis in sheep adipose tissue: requirement for gene transcription and polyamines.
Topics: Acetyl-CoA Carboxylase; Adipose Tissue; Animals; Culture Techniques; Dactinomycin; Depression, Chemical; Dexamethasone; Fatty Acids; Growth Hormone; Insulin; Lipids; Male; Mitoguazone; Ornithine Decarboxylase; Sheep; Spermidine; Time Factors; Transcription, Genetic | 1994 |
Polyamines regulate human medullary thyroid carcinoma TT-cell proliferation and secretion of calcitonin and calcitonin gene-related peptide.
Topics: Adenosylmethionine Decarboxylase; Calcitonin; Calcitonin Gene-Related Peptide; Carcinoma, Medullary; Cell Division; Eflornithine; Humans; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine; Thyroid Neoplasms; Tumor Cells, Cultured | 1994 |
Inhibition of adipose tissue lipogenesis by growth hormone: role of polyamines.
Topics: Adipose Tissue; Animals; Growth Hormone; Kinetics; Lipids; Male; Mitoguazone; Organ Culture Techniques; Ornithine Decarboxylase; Sheep; Spermidine | 1993 |
Increased spermidine or spermine level is essential for hepatocyte growth factor-induced DNA synthesis in cultured rat hepatocytes.
Topics: Adenosylmethionine Decarboxylase; Animals; Cells, Cultured; DNA; Eflornithine; Hepatocyte Growth Factor; Liver; Male; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Rats; Rats, Wistar; Spermidine; Spermine | 1994 |
Characterization of a COS cell line deficient in polyamine transport.
Topics: Animals; Biological Transport; Cell Division; Cell Line; Cloning, Molecular; Culture Media; Mitoguazone; Plasmids; Polyamines; Putrescine; Spermidine; Spermine; Transfection | 1994 |
Radiosensitivity of polyamine-depleted HeLa cells and modulation by the aminothiol WR-1065.
Topics: Cell Survival; Clone Cells; Deoxyadenosines; DNA Damage; Dose-Response Relationship, Radiation; Eflornithine; HeLa Cells; Humans; Kinetics; Mercaptoethylamines; Mitoguazone; Polyamines; Putrescine; Radiation-Protective Agents; Spermidine; Spermine; Time Factors; Tumor Stem Cell Assay; X-Rays | 1994 |
TGF-beta 1 inhibits polyamine biosynthesis in K 562 leukemic cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosylmethionine Decarboxylase; Apoptosis; Cell Division; Cell Line; Dose-Response Relationship, Drug; Eflornithine; Humans; Isoquinolines; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mitoguazone; Ornithine Decarboxylase; Piperazines; Polyamines; Protein Kinase Inhibitors; Putrescine; Spermidine; Spermine; Transforming Growth Factor beta; Tumor Cells, Cultured | 1993 |
Inhibition of polyamine synthesis alters hair follicle function and fiber composition.
Topics: Adenosylmethionine Decarboxylase; Animals; Culture Media; Eflornithine; Enzyme Inhibitors; Gene Expression; Hair; Hair Follicle; Keratins; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Sheep; Spermidine; Spermine | 1996 |
Putrescine transport in differentiated Caco-2 cells.
Topics: Biological Transport, Active; Caco-2 Cells; Cystamine; Enzyme Inhibitors; Guanidines; Humans; In Vitro Techniques; Mitoguazone; Putrescine; Spermidine; Spermine | 1996 |
Polyamines as modulators of microcycle conidiation in Aspergillus flavus.
Topics: Aspergillus flavus; Cell Division; Cyclohexylamines; Eflornithine; Enzyme Inhibitors; Mitoguazone; Putrescine; Spermidine | 1996 |
4-Amidinoindan-1-one 2'-amidinohydrazone (CGP 48664A) exerts in vitro growth inhibitory effects that are not only related to S-adenosylmethionine decarboxylase (SAMdc) inhibition.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Antineoplastic Agents; Cell Division; Deoxyadenosines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indans; Leukemia L1210; Mitoguazone; Spermidine; Spermine; Tumor Cells, Cultured | 1997 |
Growth inhibition of Helicobacter pylori by a polyamine synthesis inhibitor, methylglyoxal bis(cyclopentylamidinohydrazone).
Topics: Anti-Bacterial Agents; Bacterial Proteins; DNA, Bacterial; Enzyme Inhibitors; Helicobacter Infections; Helicobacter pylori; Humans; In Vitro Techniques; Mitoguazone; Polyamines; Putrescine; RNA, Bacterial; Spermidine | 1997 |
Selective labelling of cell-surface polyamine-binding proteins on leukaemic and solid-tumour cell types using a new polyamine photoprobe.
Topics: Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Cell Membrane; Cross-Linking Reagents; Humans; Intracellular Signaling Peptides and Proteins; Iodine Radioisotopes; Kinetics; Leukemia L1210; Lung Neoplasms; Membrane Proteins; Mice; Mitoguazone; Photoaffinity Labels; Polyamines; Spermidine; Spermine; Tumor Cells, Cultured | 1997 |
Sensitization of tnf-induced apoptosis with polyamine synthesis inhibitors in different human and murine tumour cell lines.
Topics: Amidines; Animals; Antineoplastic Agents; Apoptosis; Eflornithine; Enzyme Inhibitors; Fas Ligand Protein; Granulocyte-Macrophage Colony-Stimulating Factor; HeLa Cells; Humans; Indans; Membrane Glycoproteins; Mice; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine; T-Lymphocytes; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Trypanosoma cruzi has not lost its S-adenosylmethionine decarboxylase: characterization of the gene and the encoded enzyme.
Topics: Adenosylmethionine Decarboxylase; Amino Acid Sequence; Animals; Base Sequence; Blotting, Southern; Chromosome Mapping; DNA, Protozoan; Enzyme Inhibitors; Escherichia coli; Gene Expression; Genes, Protozoan; Kinetics; Mitoguazone; Molecular Sequence Data; Putrescine; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Spermidine; Spermine; Trypanosoma cruzi | 1998 |
Prolactin stimulation of iodide uptake and incorporation into protein is polyamine-dependent in mouse mammary gland explants.
Topics: Adenosylmethionine Decarboxylase; Animals; Eflornithine; Enzyme Inhibitors; Female; Iodides; Iodine Radioisotopes; Mammary Glands, Animal; Mice; Mitoguazone; Ornithine Decarboxylase Inhibitors; Pregnancy; Prolactin; Proteins; Spermidine | 2000 |
Involvement of polyamines in the chilling tolerance of cucumber cultivars.
Topics: Adaptation, Physiological; Cucumis sativus; Enzyme Inhibitors; Freezing; Hydrogen Peroxide; Microsomes; Mitoguazone; NADP; Oxidation-Reduction; Photoperiod; Plant Leaves; Putrescine; Reactive Oxygen Species; Spermidine; Superoxides | 2000 |
Polyamine regulation of ornithine decarboxylase and its antizyme in intestinal epithelial cells.
Topics: Animals; Cell Line; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Fetal Proteins; Intestines; Mitoguazone; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine | 2001 |
Cellular pharmacodynamics of the cytotoxic guanidino-containing drug CHS 828. Comparison with methylglyoxal-bis(guanylhydrazone).
Topics: Antineoplastic Agents; Carboxy-Lyases; Cell Death; Cyanides; DNA; Dose-Response Relationship, Drug; Fluorometry; Guanidines; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Mitoguazone; Protein Biosynthesis; Spermidine; U937 Cells | 2001 |
In vivo inhibition of polyamine biosynthesis and growth in tobacco ovary tissues.
Topics: Adenosylmethionine Decarboxylase; Arginine; Carboxy-Lyases; Eflornithine; Enzyme Inhibitors; Mitoguazone; Nicotiana; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Plants, Toxic; Polyamines; Putrescine; Spermidine; Spermine | 1985 |
Polyamine regulation of the rat pro-opiomelanocortin gene expression in AtT-20 cells.
Topics: Animals; Cell Division; Cell Line; Enzyme Inhibitors; Gene Expression; Mice; Mitoguazone; Polyamines; Pro-Opiomelanocortin; Putrescine; Rats; Receptors, Calcium-Sensing; Receptors, Cell Surface; Spermidine; Spermine | 2001 |
Enhanced susceptibility of photosynthesis to low-temperature photoinhibition due to interruption of chill-induced increase of S-adenosylmethionine decarboxylase activity in leaves of spinach (Spinacia oleracea L.).
Topics: Acclimatization; Adenosylmethionine Decarboxylase; Carboxy-Lyases; Chlorophyll; Chloroplasts; Cold Temperature; Electron Transport; Enzyme Inhibitors; Light; Light-Harvesting Protein Complexes; Lipid Peroxidation; Mitoguazone; Photosynthesis; Photosynthetic Reaction Center Complex Proteins; Plant Leaves; Polyamines; Putrescine; RNA, Messenger; Spermidine; Spinacia oleracea; Thylakoids | 2002 |
Polyamine-dependent migration of retinal pigment epithelial cells.
Topics: Adenosylmethionine Decarboxylase; Cell Line; Cell Movement; Chromatography, High Pressure Liquid; Eflornithine; Enzyme Inhibitors; Humans; Mitoguazone; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pigment Epithelium of Eye; Putrescine; Spermidine; Spermine | 2002 |
Involvement of polyamines in root development at low temperature in the subantarctic cruciferous species Pringlea antiscorbutica.
Topics: Acclimatization; Agmatine; Antarctic Regions; Arginine; Brassicaceae; Carboxy-Lyases; Cold Temperature; Drug Interactions; Eflornithine; Germination; Glutarates; Mitoguazone; Ornithine Decarboxylase; Plant Roots; Plant Shoots; Polyamines; Putrescine; Seeds; Spermidine; Spermine | 2002 |
Polyamine uptake is necessary for a normal biochemical maturation of astrocytes in culture.
Topics: Animals; Astrocytes; Biogenic Polyamines; Cell Differentiation; Cell Division; Cells, Cultured; Cerebellum; DNA; Down-Regulation; Eflornithine; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Mice; Mitoguazone; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine; Thymidine; Up-Regulation | 2002 |
Transport of polyamines in Drosophila S2 cells: kinetics, pharmacology and dependence on the plasma membrane proton gradient.
Topics: Animals; Biological Transport; Calcium; Carrier Proteins; Cell Line; Cell Membrane; Chlorides; Drosophila melanogaster; Hydrogen-Ion Concentration; Kinetics; Mitoguazone; Paraquat; Potassium; Proton-Motive Force; Sodium; Spermidine; Spermine | 2006 |
Biological activity of antitumoural MGBG: the structural variable.
Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Binding Sites; Calcium; Cell Membrane Permeability; Computer Simulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepatocytes; Hydrogen-Ion Concentration; Male; Mitochondria, Liver; Mitoguazone; Models, Biological; Models, Molecular; Quantum Theory; Rats; Rats, Wistar; Spermidine; Spermine; Structure-Activity Relationship; Time Factors | 2008 |
Effects of polyamines and polyamine biosynthetic inhibitors on mitotic activity of Allium cepa root tips.
Topics: Cycloheximide; Eflornithine; Enzyme Inhibitors; Meristem; Mitoguazone; Mitosis; Onions; Polyamines; Protein Synthesis Inhibitors; Putrescine; Spermidine; Spermine | 2008 |
Effects of polyamines on the DNA-reactive properties of dimeric mithramycin complexed with cobalt(II): implications for anticancer therapy.
Topics: Antibiotics, Antineoplastic; Binding, Competitive; Cell Line, Tumor; Cell Survival; Circular Dichroism; Cobalt; Dimerization; DNA, Bacterial; DNA, Superhelical; Humans; Mitoguazone; Plicamycin; Spermidine; Spermine | 2009 |
Grain Filling Characteristics and Their Relations with Endogenous Hormones in Large- and Small-Grain Mutants of Rice.
Topics: Abscisic Acid; Edible Grain; Endosperm; Enzyme-Linked Immunosorbent Assay; Mitoguazone; Oryza; Plant Growth Regulators; Plants, Genetically Modified; Polyamines; Putrescine; Spermidine; Zeatin | 2016 |