spermidine and leucine

spermidine has been researched along with leucine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199022 (62.86)18.7374
1990's8 (22.86)18.2507
2000's1 (2.86)29.6817
2010's2 (5.71)24.3611
2020's2 (5.71)2.80

Authors

AuthorsStudies
Anderson, CW; Atkins, JF; Gesteland, RF; Lewis, JB1
Bey, P; Böhlen, P; Mamont, PS; McCann, PP; Schuber, F; Tardif, C1
Thiebe, R1
Fresco, JR; Karpel, RL; Lesk, AM; Miller, NS1
Hardesty, B; Konecki, D; Kramer, G; Pinphanichakarn, P1
Arena, N; Bosi, P; Caruso, A; Pellati, A; Stabellini, G1
Linebaugh, BE; Rillema, JA1
Edwards, ML; Snyder, RD1
Koumoto, Y; Shikami, S; Shinoda, S; Yamamoto, S1
Kenny, GE; Sjöström, KE1
Gebhardt, R; Mecke, D; Schulz, WA1
Morgan, DM1
Fong, WF; Pang, SF; Shin, WW; Wong, PC1
de Varebeke, PJ1
Friedman, SM; Schlanger, G1
Srinivasan, PR; Young, DV1
Alarcon, RA1
Hikami, K; Hirose, S; Igarashi, K; Sugawara, K1
Lavis, V; Sakai, T; Williams, RH1
Comolli, R1
Smith, TA1
Breitman, TR; Finkleman, A; Rabinovitz, M1
Ariel, M; Grossowicz, N1
Bellantone, RA; Canellakis, ES; Friedman, SJ1
Datta, RK; Ghosh, JJ1
Auberger, P; Le Cam, A; Le Cam, G; Samson, M1
Boor, PJ; Gutkowska, J; Haile, C; Tipnis, UR1
Erecińska, M; Kuo, N; Michalik, M1
Creati, B; Di Primio, R; Stabellini, G; Trubiani, O1
Galston, AW; Kaur-Sawhney, R; Tiburcio, AF1
Díaz-Troya, S; Najib, S; Sánchez-Margalet, V1
Kroemer, G; Madeo, F; Mariño, G; Pietrocola, F1
Aouida, M; Ramotar, D1
Cronk, S; Dinara, S; Ikhlef, H; Massaro, C; Moots, H; Phanstiel, O; Thomas, J1
Abraham, SJK; Dedeepiya, VD; Ikewaki, N; Iwasaki, M; Levy, GA; Preethy, S; Raghavan, K; Ranganathan, N; Senthilkumar, R; Srinivasan, S; Yamamoto, N1

Reviews

1 review(s) available for spermidine and leucine

ArticleYear
The occurrence, metabolism and functions of amines in plants.
    Biological reviews of the Cambridge Philosophical Society, 1971, Volume: 46, Issue:2

    Topics: Alkaloids; Amination; Amines; Amino Acids; Biodegradation, Environmental; Carbon Isotopes; Decarboxylation; Epinephrine; Fungi; Histamine; Leucine; Norepinephrine; Oxidation-Reduction; Oxygen Consumption; Phenethylamines; Plant Growth Regulators; Plant Viruses; Plants; Polyamines; Serotonin; Spermidine; Spermine; Tyramine; Valine

1971

Other Studies

34 other study(ies) available for spermidine and leucine

ArticleYear
Enhanced differential synthesis of proteins in a mammalian cell-free system by addition of polyamines.
    The Journal of biological chemistry, 1975, Jul-25, Volume: 250, Issue:14

    Topics: Animals; Ascites; Carbon Radioisotopes; Cell-Free System; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Coliphages; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Leucine; Magnesium; Methionine; Polyamines; Protein Biosynthesis; Putrescine; Rabbits; Reticulocytes; RNA, Messenger; RNA, Ribosomal; Simian virus 40; Sodium Dodecyl Sulfate; Spermidine; Spermine; Sulfur Radioisotopes; Templates, Genetic

1975
Alpha-methyl ornithine, a potent competitive inhibitor of ornithine decarboxylase, blocks proliferation of rat hepatoma cells in culture.
    Proceedings of the National Academy of Sciences of the United States of America, 1976, Volume: 73, Issue:5

    Topics: Cell Division; Cells, Cultured; DNA Replication; Kinetics; Leucine; Ornithine; Putrescine; Spermidine; Spermine

1976
Aminoacylation of tRNA. Magnesium requirement and spermidine effect.
    FEBS letters, 1975, Mar-01, Volume: 51, Issue:1

    Topics: Amino Acyl-tRNA Synthetases; Escherichia coli; Kinetics; Leucine; Magnesium; RNA, Transfer; Saccharomyces cerevisiae; Spermidine; Transfer RNA Aminoacylation

1975
Stabilization of the native tertiary stucture of yeast tRNALeu3 by cationic metal complexes.
    Journal of molecular biology, 1975, Oct-05, Volume: 97, Issue:4

    Topics: Binding Sites; Cobalt; Iridium; Kinetics; Leucine; Magnesium; Mathematics; Nucleic Acid Conformation; Nucleic Acid Renaturation; Platinum; Potassium Chloride; RNA, Transfer; Saccharomyces cerevisiae; Spermidine

1975
Polyamines are necessary for maximum in vitro synthesis of globin peptides and play a role in chain initiation.
    Archives of biochemistry and biophysics, 1975, Volume: 169, Issue:1

    Topics: Animals; Cell-Free System; Dialysis; Edeine; Globins; Kinetics; Leucine; Magnesium; Peptide Chain Initiation, Translational; Peptide Fragments; Polyamines; Potassium Chloride; Rabbits; Reticulocytes; Ribosomes; Spermidine; Spermine; Stimulation, Chemical; Ultrafiltration

1975
Effects of spermidine synthase inhibition in cultured chick embryo fibroblasts.
    Cell biology international reports, 1992, Volume: 16, Issue:4

    Topics: Animals; Cell Division; Cells, Cultured; Chick Embryo; Cyclohexylamines; DNA; Fibroblasts; Leucine; Protein Biosynthesis; Putrescine; Spermidine; Spermidine Synthase; Spermine

1992
Polyamine influences on the prolactin stimulation of phosphoprotein synthesis in hydroxyurea synchronized MCF-7 human mammary epithelial cells.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1991, Volume: 23, Issue:9

    Topics: Cell Cycle; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Female; G1 Phase; Humans; Hydroxyurea; Insulin; Interphase; Leucine; Ornithine; Phosphoproteins; Polyamines; Prolactin; Protein Processing, Post-Translational; Putrescine; S Phase; Spermidine; Tritium

1991
Effects of polyamine analogs on the extent and fidelity of in vitro polypeptide synthesis.
    Biochemical and biophysical research communications, 1991, May-15, Volume: 176, Issue:3

    Topics: Animals; Kinetics; Leucine; Peptide Biosynthesis; Peptides; Polyamines; Protein Biosynthesis; Rabbits; Reticulocytes; Spermidine; Structure-Activity Relationship

1991
Effect of norspermidine and its related triamines on the cell-free polyphenylalanine synthesizing system from Vibrio parahaemolyticus.
    Microbiology and immunology, 1990, Volume: 34, Issue:7

    Topics: Amines; Ammonia; Dose-Response Relationship, Drug; Leucine; Magnesium; Peptides; Potassium; Spermidine; Vibrio parahaemolyticus

1990
Differences in accumulation of radiolabeled amino acids and polyamines by Mycoplasma and Acholeplasma species.
    International journal of systematic bacteriology, 1990, Volume: 40, Issue:4

    Topics: Acholeplasma; Amino Acids; Leucine; Methionine; Molecular Weight; Mycoplasma; Polyamines; Putrescine; Spermidine; Sulfur Isotopes

1990
Spermidine level and protein synthesis are coregulated in nonproliferating hepatocytes.
    Biological chemistry Hoppe-Seyler, 1989, Volume: 370, Issue:7

    Topics: Animals; Biogenic Polyamines; Dexamethasone; In Vitro Techniques; Insulin; Leucine; Liver; Male; Ornithine Decarboxylase; Propanolamines; Protein Biosynthesis; Rats; Rats, Inbred Strains; Spermidine

1989
Oxidized polyamines and the growth of human vascular endothelial cells. Prevention of cytotoxic effects by selective acetylation.
    The Biochemical journal, 1987, Mar-01, Volume: 242, Issue:2

    Topics: Acetylation; Amine Oxidase (Copper-Containing); Amino Acids; Cell Survival; Cells, Cultured; Endothelium; Humans; Leucine; Macromolecular Substances; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Spermidine; Spermine; Umbilical Veins

1987
Limited blood-brain barrier transport of polyamines.
    Journal of neurochemistry, 1985, Volume: 44, Issue:4

    Topics: Adenosine; Animals; Arginine; Binding, Competitive; Biological Transport; Blood-Brain Barrier; Brain; Choline; Diffusion; Kinetics; Leucine; Male; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine

1985
Proceedings: Effect of polyamines on aminoacylation of tRNA from Phasaeolus vulgaris.
    Archives internationales de physiologie et de biochimie, 1974, Volume: 82, Issue:4

    Topics: Amino Acyl-tRNA Synthetases; Leucine; Magnesium; Plants; Putrescine; RNA, Transfer; Spermidine; Spermine; Transfer RNA Aminoacylation

1974
Ambiguity in a polypeptide-synthesizing extract from Saccharomyces cerevisiae.
    Journal of bacteriology, 1973, Volume: 115, Issue:1

    Topics: Acylation; Amino Acyl-tRNA Synthetases; Carbon Isotopes; Cell Fractionation; Cell-Free System; Cytoplasm; Ethanol; Fungal Proteins; Hydrogen-Ion Concentration; Isoleucine; Leucine; Magnesium; Neomycin; Peptide Biosynthesis; Phenylalanine; Poly U; Protein Biosynthesis; RNA, Transfer; Saccharomyces cerevisiae; Serine; Spermidine; Spermine; Streptomycin; Temperature

1973
Growth of ribonucleic acid bacteriophage f2 in a conditional putrescine auxotroph of Escherichia coli: evidence for a polyamine role in translation.
    Journal of bacteriology, 1974, Volume: 117, Issue:3

    Topics: Arginine; Carbon Radioisotopes; Cell-Free System; Coliphages; Culture Media; DNA-Directed RNA Polymerases; Escherichia coli; Leucine; Mutation; Ornithine; Protein Biosynthesis; Putrescine; Rifampin; RNA, Messenger; RNA, Viral; Spermidine; Tritium; Uracil; Viral Proteins

1974
Acrolein, a component of a universal cell-growth regulatory system: a theory.
    Journal of theoretical biology, 1972, Volume: 37, Issue:1

    Topics: Aldehydes; Alkenes; Animals; Antineoplastic Agents; Cells, Cultured; Cricetinae; Cyclophosphamide; Depression, Chemical; DNA; Electron Transport; Growth Substances; Ketones; Leucine; Models, Biological; Oxidation-Reduction; RNA; Spermidine; Spermine; Sulfhydryl Reagents; Thymidine; Thymus Gland; Tissue Extracts; Tritium; Uridine

1972
Effect of polyamines on polypeptide synthesis in rat liver cell-free system.
    Biochimica et biophysica acta, 1973, Mar-19, Volume: 299, Issue:2

    Topics: Animals; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Fluoresceins; In Vitro Techniques; Isoleucine; Leucine; Liver; Magnesium; Male; Microsomes, Liver; Peptide Biosynthesis; Phenylalanine; Polyamines; Polyribosomes; Rats; Spectrophotometry, Ultraviolet; Spermidine; Spermine; Subcellular Fractions

1973
Incorporation of leucine into protein by isolated fat cells--effects of agents which stimulate glucose metabolism and inhibit lipolysis.
    Biochemical pharmacology, 1973, Nov-01, Volume: 22, Issue:21

    Topics: Adenine Nucleotides; Adipose Tissue; Animals; Concanavalin A; Cysteine; Glucose; In Vitro Techniques; Insulin; Leucine; Lipid Metabolism; Nystatin; Ouabain; Polyamines; Propylamines; Protein Biosynthesis; Pyruvates; Rats; Spermidine; Swine; Tolbutamide; Tritium; Vitamin K

1973
Polyamine effects on 14C-leucine transfer to microsomal protein in a rat liver cell free system during ageing.
    Experimental gerontology, 1973, Volume: 8, Issue:6

    Topics: Aging; Animals; Carbon Radioisotopes; Cell-Free System; Centrifugation; Cytoplasm; Isotope Labeling; Leucine; Microsomes, Liver; Polyamines; Protein Biosynthesis; Rats; Ribonucleases; RNA, Transfer; Spermidine; Spermine

1973
Methionineless death in Escherichia coli.
    Journal of bacteriology, 1971, Volume: 108, Issue:3

    Topics: Amino Acyl-tRNA Synthetases; Arginine; Bacterial Proteins; Bacteriological Techniques; Carbon Isotopes; Cell Survival; Culture Media; Decarboxylation; DNA, Bacterial; Escherichia coli; Filtration; Isoleucine; Leucine; Methionine; Proline; Spermidine; Spermine; Thymine; Tryptophan; Uracil

1971
Effect of spermine on the uptake of amino acids in Micrococcus lysodeikticus.
    Journal of bacteriology, 1972, Volume: 111, Issue:2

    Topics: Alanine; Amino Acids; Autoanalysis; Azides; Carbon Isotopes; Carrier Proteins; Cell Membrane; Dinitrophenols; Glucose; Glycine; Isoleucine; Leucine; Micrococcus; Polyamines; Protein Binding; Spermidine; Spermine; Temperature; Valine

1972
Ornithine decarboxylase activity in synchronously growing Don C cells.
    Biochimica et biophysica acta, 1972, Jan-28, Volume: 261, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Benzocycloheptenes; Carbon Isotopes; Carboxy-Lyases; Cell Line; Cells, Cultured; Cricetinae; Cycloheximide; Dactinomycin; DNA; Leucine; Lung; Ornithine; Protein Biosynthesis; Putrescine; RNA; Spermidine; Spermine; Thymidine; Tritium; Uridine

1972
Mescaline-induced changes of brain cortex ribosomes. Effect of mescaline on amino acid incorporating ability of ribosomes.
    Brain research, 1971, Oct-08, Volume: 33, Issue:1

    Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cerebral Cortex; Goats; Leucine; Mescaline; Nerve Tissue Proteins; Phenylalanine; Ribosomes; RNA; Spermidine; Spermine

1971
Effects of polyamines on cyclic AMP-mediated stimulation of amino acid transport in isolated rat hepatocytes.
    Journal of cellular physiology, 1983, Volume: 117, Issue:2

    Topics: Aminoisobutyric Acids; Animals; Biological Transport; Bucladesine; Cadaverine; Cyclic AMP; Glucagon; Kinetics; Leucine; Liver; Male; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine

1983
Polyamine regulation of atrial natriuretic peptide in cultured cardiocytes.
    Regulatory peptides, 1994, Jul-14, Volume: 52, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Cells, Cultured; Eflornithine; L-Lactate Dehydrogenase; Leucine; Myocardium; Ornithine Decarboxylase Inhibitors; Polyamines; Protein Biosynthesis; Putrescine; Rats; Spermidine

1994
Inhibition of glutamate dehydrogenase in brain mitochondria and synaptosomes by Mg2+ and polyamines: a possible cause for its low in vivo activity.
    Journal of neurochemistry, 1994, Volume: 63, Issue:2

    Topics: Adenosine Diphosphate; Analysis of Variance; Animals; Brain; Glutamate Dehydrogenase; Guanidines; Kinetics; Leucine; Magnesium; Male; Mesencephalon; Mitochondria; Prosencephalon; Rats; Rats, Wistar; Spermidine; Synaptosomes

1994
Intracellular distribution of polyamines in human lymphoblastoid cell line during phorbol ester-induced differentiation.
    Biochemistry and molecular biology international, 1996, Volume: 39, Issue:4

    Topics: B-Lymphocytes; Cell Cycle; Cell Differentiation; Cell Division; Humans; Leucine; Leukemia, Lymphoid; Putrescine; Spermidine; Spermine; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured

1996
Polyamine metabolism and osmotic stress. II. Improvement of oat protoplasts by an inhibitor of arginine decarboxylase.
    Plant physiology, 1986, Volume: 82

    Topics: Arginine; Avena; Carboxy-Lyases; Cell Division; Leucine; Ornithine Decarboxylase Inhibitors; Osmotic Pressure; Plant Leaves; Polyamines; Protoplasts; Putrescine; Spermidine; Spermine; Thymidine; Uridine

1986
eNOS, nNOS, cGMP and protein kinase G mediate the inhibitory effect of pancreastatin, a chromogranin A-derived peptide, on growth and proliferation of hepatoma cells.
    Regulatory peptides, 2005, Feb-15, Volume: 125, Issue:1-3

    Topics: Aminoquinolines; Animals; Arginine; Calcium; Carbazoles; Carcinoma, Hepatocellular; Cell Enlargement; Cell Proliferation; Chromogranin A; Chromogranins; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; DNA; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Isoenzymes; Leucine; Liver; MAP Kinase Signaling System; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Ornithine; Pancreatic Hormones; Peptides; Phospholipase C beta; Protein Isoforms; Rats; Receptors, Atrial Natriuretic Factor; Spermidine; Thymidine; Time Factors; Type C Phospholipases

2005
Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers.
    Autophagy, 2014, Volume: 10, Issue:11

    Topics: Acetyl Coenzyme A; Anacardic Acids; Animals; Autophagy; Caloric Restriction; Catalysis; Catechin; Curcumin; Food Deprivation; Humans; Leucine; Mice; Models, Animal; Niacinamide; Plant Extracts; Resveratrol; Spermidine; Starvation; Stilbenes; Terpenes

2014
Identification of essential yeast genes involved in polyamine resistance.
    Gene, 2018, Nov-30, Volume: 677

    Topics: Drug Resistance, Fungal; Gene Expression Regulation, Fungal; Genes, Essential; Leucine; Mutation; Polyamines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spermidine; Spermine; Transcription Factors

2018
Serendipitous Discovery of Leucine and Methionine Depletion Agents during the Search for Polyamine Transport Inhibitors.
    Journal of medicinal chemistry, 2020, 03-26, Volume: 63, Issue:6

    Topics: Animals; Benzoxazoles; Biological Transport; CHO Cells; Cricetulus; Drug Discovery; Humans; Large Neutral Amino Acid-Transporter 1; Leucine; Methionine; Polyamines; Putrescine; Small Molecule Libraries; Spermidine; Spermine; Tyrosine

2020
Two unique biological response-modifier glucans beneficially regulating gut microbiota and faecal metabolome in a non-alcoholic steatohepatitis animal model, with potential applications in human health and disease.
    BMJ open gastroenterology, 2022, Volume: 9, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Firmicutes; Fructose; Gastrointestinal Microbiome; Glucans; Humans; Isoleucine; Leucine; Metabolome; Mice; Non-alcoholic Fatty Liver Disease; Ornithine; RNA, Ribosomal, 16S; Spermidine; Succinic Acid; Telmisartan; Tryptophan; Water

2022