spermidine and guanine

spermidine has been researched along with guanine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19904 (23.53)18.7374
1990's6 (35.29)18.2507
2000's3 (17.65)29.6817
2010's3 (17.65)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Averyhart, VM; Glick, JM; Leboy, PS1
Gibson, NW; Prakash, AS1
Igarashi, K; Ito, K; Kashiwagi, K1
Archer, MC; Gunhouse, BW; Milligan, JR1
Dixit, R; Gold, B1
Kurylo-Borowska, Z; Sedkowska, J1
Folk, JE; Lee, YB; Park, MH; Wolff, EC1
Folk, JE; Park, MH; Wolff, EC1
Folk, JE; Jakus, J; Park, MH; Wolff, EC1
Dimitriadis, EK; Joe, YA; Lee, YB; Park, MH; Wolff, EC1
Bretonniere, Y; Cadet, J; Douki, T1
Davies, DR; Park, MH; Umland, TC; Wolff, EC1
Alizadeh, A; Bathaie, SZ; Kazemi, SH; Mehdinia, A; Mousavi, MF; Shamsipur, M1
Bercovich, Z; Kahana, C; Landau, G; Park, MH1
Mandal, A; Mandal, S; Park, MH; Wolff, EC1
Esumi, M; Sakurai, S; Tanaka, M1
Ambrus-Aikelin, G; Imamura, S; Kimura, H; Kitazawa, S; Klein, MG; Kurasawa, O; Matsumoto, S; Morishita, D; Ogawa, K; Okaniwa, M; Ono, K; Saito, B; Tanaka, Y; Uchiyama, N; Yokota, A1

Reviews

1 review(s) available for spermidine and guanine

ArticleYear
Is hypusine essential for eukaryotic cell proliferation?
    Trends in biochemical sciences, 1993, Volume: 18, Issue:12

    Topics: Amino Acid Sequence; Animals; Cell Division; Cell Line; Eukaryotic Translation Initiation Factor 5A; Guanine; Humans; Lysine; Molecular Sequence Data; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Protein Precursors; RNA-Binding Proteins; Spermidine

1993

Other Studies

16 other study(ies) available for spermidine and guanine

ArticleYear
Purification and characterization of two tRNA-(guanine)-methyltransferases from rat liver.
    Biochimica et biophysica acta, 1978, Mar-29, Volume: 518, Issue:1

    Topics: Animals; Guanine; Kinetics; Liver; Male; Molecular Weight; Putrescine; Rats; Spermidine; Substrate Specificity; tRNA Methyltransferases

1978
Sequence-selective depurination, DNA interstrand cross-linking and DNA strand break formation associated with alkylated DNA.
    Carcinogenesis, 1992, Volume: 13, Issue:3

    Topics: Alkylation; Base Sequence; Cross-Linking Reagents; DNA; DNA Damage; Ellagic Acid; Ethylnitrosourea; Guanine; Methyl Methanesulfonate; Molecular Sequence Data; Spermidine

1992
Spermidine regulation of ornithine decarboxylase synthesis by a GC-rich sequence of the 5'-untranslated region.
    Biochemical and biophysical research communications, 1991, Aug-15, Volume: 178, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Composition; Base Sequence; Cytosine; Gene Expression Regulation, Enzymologic; Guanine; Kinetics; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Oligonucleotide Probes; Open Reading Frames; Ornithine Decarboxylase; Protein Biosynthesis; Protein Sorting Signals; Rabbits; Reticulocytes; RNA, Messenger; Spermidine

1991
Interaction of alpha-acetoxy-N-nitrosopyrrolidine with DNA assessed by loss of restriction endonuclease recognition sites and formation of apurinic/apyrimidinic sites.
    Carcinogenesis, 1988, Volume: 9, Issue:9

    Topics: Apurinic Acid; Cytosine; Dimethylnitrosamine; DNA; DNA Damage; DNA Restriction Enzymes; Esterases; Guanine; Methylnitrosourea; N-Nitrosopyrrolidine; Nitrosamines; Plasmids; Polynucleotides; Spermidine

1988
Inhibition of N-methyl-N-nitrosourea-induced mutagenicity and DNA methylation by ellagic acid.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:21

    Topics: Benzopyrans; DNA; Dose-Response Relationship, Drug; Ellagic Acid; Guanine; Methylation; Methylnitrosourea; Mutation; Spermidine

1986
Biosynthesis of edeine. Fractionation and characterization of enzymes responsible for biosynthesis of edeine A and B.
    Biochimica et biophysica acta, 1974, May-10, Volume: 351, Issue:1

    Topics: Aminoacylation; Anti-Bacterial Agents; Bacillus; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Glycine; Guanine; Hydrogen-Ion Concentration; Isoelectric Focusing; Kinetics; Molecular Weight; Peptide Biosynthesis; Phosphorus Radioisotopes; Polyamines; Propionates; Serine; Spermidine; Time Factors; Tritium; Tyrosine

1974
Antiproliferative effects of inhibitors of deoxyhypusine synthase. Inhibition of growth of Chinese hamster ovary cells by guanyl diamines.
    The Journal of biological chemistry, 1994, Nov-11, Volume: 269, Issue:45

    Topics: Animals; Cell Division; Cell Survival; CHO Cells; Cricetinae; Diamines; Dose-Response Relationship, Drug; Guanine; Indicators and Reagents; Kinetics; Lysine; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Protein Biosynthesis; Putrescine; Spermidine; Spermine; Structure-Activity Relationship

1994
Features of the spermidine-binding site of deoxyhypusine synthase as derived from inhibition studies. Effective inhibition by bis- and mono-guanylated diamines and polyamines.
    The Journal of biological chemistry, 1993, Jun-25, Volume: 268, Issue:18

    Topics: Animals; Binding Sites; Cells, Cultured; CHO Cells; Cricetinae; Diamines; Guanine; Male; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Rats; Spermidine

1993
Complex formation between deoxyhypusine synthase and its protein substrate, the eukaryotic translation initiation factor 5A (eIF5A) precursor.
    The Biochemical journal, 1999, May-15, Volume: 340 ( Pt 1)

    Topics: Cell Extracts; Chromatography, Affinity; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Eukaryotic Translation Initiation Factor 5A; Guanine; Humans; Hydrogen-Ion Concentration; Molecular Weight; NAD; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Protein Binding; Protein Precursors; Protons; Recombinant Fusion Proteins; RNA-Binding Proteins; Sequence Analysis; Spermidine; Temperature; Thermodynamics; Ultracentrifugation

1999
Protection against radiation-induced degradation of DNA bases by polyamines.
    Radiation research, 2000, Volume: 153, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Amidines; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Dimethyl Sulfoxide; DNA; DNA Damage; Dose-Response Relationship, Drug; Gamma Rays; Gas Chromatography-Mass Spectrometry; Guanine; Hydroxyl Radical; Oxidation-Reduction; Polyamines; Purines; Putrescine; Pyrimidines; Radiation-Protective Agents; Solutions; Spermidine; Spermine

2000
A new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme.NAD.inhibitor ternary complex.
    The Journal of biological chemistry, 2004, Jul-02, Volume: 279, Issue:27

    Topics: Alkyl and Aryl Transferases; Amino Acid Motifs; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Dimerization; Electrons; Eukaryotic Translation Initiation Factor 5A; Guanine; Humans; Hydrogen-Ion Concentration; Ions; Models, Molecular; NAD; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Protein Binding; Protein Conformation; Protein Structure, Secondary; RNA-Binding Proteins; Spermidine; X-Ray Diffraction

2004
Electrochemical DNA nano-biosensor for the study of spermidine-DNA interaction.
    Journal of pharmaceutical and biomedical analysis, 2009, Apr-05, Volume: 49, Issue:3

    Topics: Biosensing Techniques; DNA; Electrochemistry; Electrodes; Guanine; Indicators and Reagents; Nanotechnology; Spermidine; Sulfhydryl Compounds

2009
The role of polyamines in supporting growth of mammalian cells is mediated through their requirement for translation initiation and elongation.
    The Journal of biological chemistry, 2010, Apr-23, Volume: 285, Issue:17

    Topics: Animals; Cell Proliferation; Drosophila; Eflornithine; Enzyme Inhibitors; Eukaryotic Initiation Factor-2; Eukaryotic Translation Initiation Factor 5A; Guanine; Humans; Mice; NIH 3T3 Cells; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptide Initiation Factors; Phosphorylation; RNA-Binding Proteins; Spermidine; Yeasts

2010
A new non-radioactive deoxyhypusine synthase assay adaptable to high throughput screening.
    Amino acids, 2017, Volume: 49, Issue:11

    Topics: Biosynthetic Pathways; Enzyme Assays; Enzyme Inhibitors; Guanine; High-Throughput Screening Assays; Humans; Hydrogen-Ion Concentration; Kinetics; Luminescent Measurements; NAD; Oxidoreductases Acting on CH-NH Group Donors; Small Molecule Libraries; Spermidine; Substrate Specificity; Time Factors

2017
The effect of spermidine on guanine decomposition via photoinduced electron transfer in DNA.
    Organic & biomolecular chemistry, 2019, 12-18, Volume: 18, Issue:1

    Topics: DNA; Electron Transport; Guanine; Photochemical Processes; Spermidine

2019
Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase.
    Journal of medicinal chemistry, 2020, 03-26, Volume: 63, Issue:6

    Topics: Allosteric Site; Crystallography, X-Ray; Drug Discovery; Enzyme Assays; Enzyme Inhibitors; Guanine; High-Throughput Screening Assays; Humans; Indoles; Molecular Structure; NAD; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Protein Conformation; Spermidine; Structure-Activity Relationship; Thiophenes

2020