spermidine and deoxyhypusine

spermidine has been researched along with deoxyhypusine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's5 (41.67)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Folk, JE; Hershey, JW; Park, MH; Smit-McBride, Z; Wolff, EC1
Folk, JE; Park, MH; Wolff, EC1
Park, MH2
Park, MH; Wolff, EC1
Folk, JE; Liberato, DJ; Park, MH; Yergey, AL1
Cooper, HL; Folk, JE; Park, MH1
Joe, YA; Lee, YB; Park, MH; Wolff, EC1
Davies, DR; Liao, DI; Park, MH; Wolff, EC1
Bergeron, RJ; McCosar, BH; Müller, R; Smith, RE; Weimar, WR; Yao, H; Zimmerman, CO1
Folk, JE; Park, JH; Park, MH; Wolff, EC1
Alhonen, L; Hyvönen, MT; Keinänen, TA; Khomutov, AR; Khomutov, M; Kochetkov, SN; Petit, M; Vepsäläinen, J; Weisell, J1

Other Studies

12 other study(ies) available for spermidine and deoxyhypusine

ArticleYear
Comparison of the activities of variant forms of eIF-4D. The requirement for hypusine or deoxyhypusine.
    The Journal of biological chemistry, 1991, May-05, Volume: 266, Issue:13

    Topics: Animals; Cadaverine; Cells, Cultured; Chromatography, Ion Exchange; Cricetinae; Eflornithine; Escherichia coli; Eukaryotic Translation Initiation Factor 5A; Humans; Lysine; Molecular Structure; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Periodic Acid; Puromycin; RNA-Binding Proteins; Spermidine; Substrate Specificity

1991
Cleavage of spermidine as the first step in deoxyhypusine synthesis. The role of NAD.
    The Journal of biological chemistry, 1990, Mar-25, Volume: 265, Issue:9

    Topics: Animals; Chromatography, Gel; Chromatography, Ion Exchange; Eukaryotic Translation Initiation Factor 5A; Kinetics; Lysine; Male; NAD; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Protein Precursors; Rats; RNA-Binding Proteins; Spermidine; Testis

1990
Regulation of biosynthesis of hypusine in Chinese hamster ovary cells. Evidence for eIF-4D precursor polypeptides.
    The Journal of biological chemistry, 1987, Sep-15, Volume: 262, Issue:26

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; Cycloheximide; Eflornithine; Female; Fibroblasts; Gene Expression Regulation; Lysine; Ovary; Protein Biosynthesis; Protein Processing, Post-Translational; Spermidine

1987
The identification of an eukaryotic initiation factor 4D precursor in spermidine-depleted Chinese hamster ovary cells.
    The Journal of biological chemistry, 1988, Jun-05, Volume: 263, Issue:16

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; Eukaryotic Translation Initiation Factor 5A; Female; Isoelectric Point; Lysine; Ovary; Peptide Initiation Factors; Peptide Mapping; Protein Precursors; Protein Processing, Post-Translational; RNA-Binding Proteins; Spermidine

1988
Cell-free synthesis of deoxyhypusine. Separation of protein substrate and enzyme and identification of 1,3-diaminopropane as a product of spermidine cleavage.
    The Journal of biological chemistry, 1988, Oct-25, Volume: 263, Issue:30

    Topics: Animals; Cell Line; Cell-Free System; Chromatography, Ion Exchange; Cricetinae; Diamines; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Lysine; NAD; Peptide Initiation Factors; RNA-Binding Proteins; Spermidine

1988
The biosynthesis of hypusine (N epsilon-(4-amino-2-hydroxybutyl)lysine). Alignment of the butylamine segment and source of the secondary amino nitrogen.
    The Journal of biological chemistry, 1984, Oct-10, Volume: 259, Issue:19

    Topics: Animals; Butylamines; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Female; Isotope Labeling; Lysine; Mass Spectrometry; Putrescine; Spermidine

1984
The biosynthesis of protein-bound hypusine (N epsilon -(4-amino-2-hydroxybutyl)lysine). Lysine as the amino acid precursor and the intermediate role of deoxyhypusine (N epsilon -(4-aminobutyl)lysine).
    The Journal of biological chemistry, 1982, Jun-25, Volume: 257, Issue:12

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; Female; Kinetics; Lysine; Ovary; Putrescine; Radioisotope Dilution Technique; Spermidine; Tritium

1982
Enzyme-substrate intermediate at a specific lysine residue is required for deoxyhypusine synthesis. The role of Lys329 in human deoxyhypusine synthase.
    The Journal of biological chemistry, 1997, Dec-19, Volume: 272, Issue:51

    Topics: Biopolymers; Humans; Lysine; Mutagenesis, Site-Directed; Oxidoreductases Acting on CH-NH Group Donors; Spermidine; Substrate Specificity

1997
Crystal structure of the NAD complex of human deoxyhypusine synthase: an enzyme with a ball-and-chain mechanism for blocking the active site.
    Structure (London, England : 1993), 1998, Jan-15, Volume: 6, Issue:1

    Topics: Binding Sites; Crystallography, X-Ray; Humans; Hydrogen Bonding; Lysine; Models, Molecular; NAD; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Protein Conformation; Protein Processing, Post-Translational; Protein Structure, Secondary; Recombinant Proteins; Spermidine

1998
Effect of polyamine analogues on hypusine content in JURKAT T-cells.
    Journal of medicinal chemistry, 1998, Sep-24, Volume: 41, Issue:20

    Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Biological Transport; Cell Division; Chromatography, High Pressure Liquid; Dansyl Compounds; Enzyme Inhibitors; Humans; Jurkat Cells; Leukemia L1210; Lysine; Ornithine Decarboxylase Inhibitors; Spermidine; Spermine; Tumor Cells, Cultured

1998
Reversal of the deoxyhypusine synthesis reaction. Generation of spermidine or homospermidine from deoxyhypusine by deoxyhypusine synthase.
    The Journal of biological chemistry, 2003, Aug-29, Volume: 278, Issue:35

    Topics: Eukaryotic Translation Initiation Factor 5A; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Chemical; NAD; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Putrescine; RNA-Binding Proteins; Spermidine; Time Factors; Trichloroacetic Acid

2003
Enantiomers of 3-methylspermidine selectively modulate deoxyhypusine synthesis and reveal important determinants for spermidine transport.
    ACS chemical biology, 2015, Jun-19, Volume: 10, Issue:6

    Topics: Biological Transport; Cell Line, Tumor; Eflornithine; Eukaryotic Translation Initiation Factor 5A; Gene Expression; Humans; Lysine; Male; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Protein Processing, Post-Translational; RNA-Binding Proteins; Spermidine; Stereoisomerism; Substrate Specificity

2015