Page last updated: 2024-08-24

sparfloxacin and rifampin

sparfloxacin has been researched along with rifampin in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (25.00)18.2507
2000's10 (41.67)29.6817
2010's8 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Khanna, A; Pareek, PK; Raj, VS; Rattan, A; Saini, KS; Sharma, P; Singh, H; Sood, R; Tarai, B; Upadhyay, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Artursson, P; Mateus, A; Matsson, P1
Balakrishnan, G; Bhat, J; Chatterji, M; Dinesh, N; Ghorpade, S; Gorai, G; Guptha, S; Humnabadkar, V; Iyer, PS; Jena, LK; Kaur, P; Khadtare, P; Naik, M; Nandishaiah, R; Narayan, A; Naviri, LK; Panda, M; Ramachandran, V; Sharma, S1
Cheng, XW; Fan, YL; Feng, LS; Wu, JB; Zhang, FZ1
Grosset, JH; Ji, B; Perani, EG; Petinon, C1
Hadley, WK; Nassos, PS; Sanders, CA; Yajko, DM1
Chehl, SK; Gelber, RH; Murray, LP; Richard, V; Siu, P; Tsang, M1
García, I; Pascual, A; Perea, EJ; Ramirez de Arellano, E1
Arvieux, C; Avril, JL; Cartier, F; Jacquelinet, C; Michelet, C; Vu, N1
Horgen, L; Legrand, E; Rastogi, N1
Deb, DK; Srivastava, BS; Srivastava, KK; Srivastava, R1
Kashiwabara, Y; Matsuoka, M; Namisato, M1
Boukriche, Y; Fantin, B; Masson, C; Zarrouk, V1
Bentoucha, A; Dega, H; Grosset, J; Jarlier, V; Robert, J1
Higashide, M; Kikuchi, K; Ohtsuka, M; Okada, K; Shundo, K; Sunakawa, K1
Gidoh, M1
Ashraf, W; Barrett, DA; Bayston, R; Chen, X; Fay, M; Fisher, LE; Hook, AL; Parkinson, R; Parmenter, CD; Scurr, DJ; Smith, EF; Yousef, A1

Reviews

1 review(s) available for sparfloxacin and rifampin

ArticleYear
Fluoroquinolone derivatives and their anti-tubercular activities.
    European journal of medicinal chemistry, 2018, Feb-25, Volume: 146

    Topics: Animals; Antitubercular Agents; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis

2018

Other Studies

23 other study(ies) available for sparfloxacin and rifampin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; DNA Gyrase; DNA Mutational Analysis; DNA-Directed RNA Polymerases; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; India; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Point Mutation; Polymerase Chain Reaction; Rifampin

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
2-Phenylindole and Arylsulphonamide: Novel Scaffolds Bactericidal against Mycobacterium tuberculosis.
    ACS medicinal chemistry letters, 2014, Sep-11, Volume: 5, Issue:9

    Topics:

2014
Bactericidal activities of single or multiple doses of various combinations of new antileprosy drugs and/or rifampin against M. leprae in mice.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1992, Volume: 60, Issue:4

    Topics: Animals; Clarithromycin; Disease Models, Animal; Female; Fluoroquinolones; Foot; Hindlimb; Immunocompetence; Leprostatic Agents; Leprosy; Mice; Microbial Sensitivity Tests; Minocycline; Mycobacterium leprae; Ofloxacin; Quinolones; Rifampin

1992
In vitro susceptibility of Mycobacterium avium complex to the new fluoroquinolone sparfloxacin (CI-978; AT-4140) and comparison with ciprofloxacin.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Anti-Infective Agents; Ciprofloxacin; Drug Synergism; Ethambutol; Fluoroquinolones; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Rifampin

1990
Activity of combinations of dapsone, rifampin, minocycline, clarithromycin, and sparfloxacin against M. leprae-infected mice.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1995, Volume: 63, Issue:2

    Topics: Animals; Anti-Infective Agents; Clarithromycin; Dapsone; Drug Therapy, Combination; Female; Fluoroquinolones; Leprosy; Mice; Mice, Inbred BALB C; Minocycline; Quinolones; Rifampin

1995
Activity of sparfloxacin on Staphylococcus epidermidis attached to plastic catheters.
    The Journal of antimicrobial chemotherapy, 1995, Volume: 36, Issue:2

    Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Biocompatible Materials; Biofilms; Catheterization; Drug Therapy, Combination; Fluoroquinolones; Microbial Sensitivity Tests; Plastics; Polytetrafluoroethylene; Polyurethanes; Quinolones; Rifampin; Staphylococcus epidermidis

1995
Comparative activities of new fluoroquinolones, alone or in combination with amoxicillin, trimethoprim-sulfamethoxazole, or rifampin, against intracellular Listeria monocytogenes.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:1

    Topics: Amoxicillin; Anti-Infective Agents; Colony Count, Microbial; Dose-Response Relationship, Drug; Fluoroquinolones; HeLa Cells; Humans; Levofloxacin; Listeria monocytogenes; Ofloxacin; Quinolones; Rifampin; Sulfamethoxazole; Trimethoprim

1997
Postantibiotic effect of amikacin, rifampin, sparfloxacin, clofazimine and clarithromycin against Mycobacterium avium.
    Research in microbiology, 1997, Volume: 148, Issue:8

    Topics: Amikacin; Anti-Bacterial Agents; Bacteriological Techniques; Clarithromycin; Clofazimine; Colony Count, Microbial; Fluoroquinolones; Humans; Mycobacterium avium Complex; Quinolones; Rifampin; Serum Bactericidal Test

1997
Bioluminescent Mycobacterium aurum expressing firefly luciferase for rapid and high throughput screening of antimycobacterial drugs in vitro and in infected macrophages.
    Biochemical and biophysical research communications, 2000, Dec-20, Volume: 279, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antitubercular Agents; Cell Line; Coleoptera; Fluoroquinolones; Genes, Reporter; Luciferases; Luminescent Measurements; Macrophages; Mice; Microbial Sensitivity Tests; Mycobacterium; Ofloxacin; Recombinant Proteins; Rifampin; Streptomycin; Transfection

2000
A Mycobacterium leprae isolate resistant to dapsone, rifampin, ofloxacin and sparfloxacin.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 2000, Volume: 68, Issue:4

    Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Clarithromycin; Clofazimine; Colony Count, Microbial; Dapsone; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Leprostatic Agents; Leprosy; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Mycobacterium leprae; Ofloxacin; Rifampin

2000
[Efficacy of the sparfloxacin-ethambutol combination in a case of cerebral tuberculosis].
    La Revue de medecine interne, 2002, Volume: 23, Issue:1

    Topics: Adult; Anti-Infective Agents; Antitubercular Agents; Ethambutol; Female; Fluoroquinolones; Humans; Isoniazid; Rifampin; Tuberculosis, Central Nervous System

2002
Bactericidal activity of rifampin-amikacin against Mycobacterium ulcerans in mice.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:10

    Topics: Amikacin; Animals; Anti-Bacterial Agents; Clarithromycin; Colony Count, Microbial; Disease Models, Animal; Drug Therapy, Combination; Female; Fluoroquinolones; Foot; Mice; Mice, Inbred BALB C; Mycobacterium Infections, Nontuberculous; Mycobacterium ulcerans; Rifampin; Skin Ulcer

2002
[Susceptibility testing and molecular epidemiology of clinical strains of Bordetella pertussis isolated in Japan from 2001 to 2002].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2004, Volume: 78, Issue:5

    Topics: Anti-Bacterial Agents; Bordetella pertussis; Child, Preschool; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Erythromycin; Female; Fluoroquinolones; Humans; Infant; Male; Microbial Sensitivity Tests; Molecular Epidemiology; Rifampin; Tetracyclines; Whooping Cough

2004
[In-vitro and in-vivo activities of moxifloxacin and garenoxacin against Mycobacterium leprae].
    Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association, 2007, Volume: 76, Issue:1

    Topics: Animals; Anti-Infective Agents; Aza Compounds; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gatifloxacin; Leprostatic Agents; Levofloxacin; Mice; Mice, Inbred BALB C; Mice, Nude; Moxifloxacin; Mycobacterium leprae; Ofloxacin; Quinolines; Rifampin

2007
Biomaterial modification of urinary catheters with antimicrobials to give long-term broadspectrum antibiofilm activity.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Mar-28, Volume: 202

    Topics: Anti-Infective Agents; Bacteria; Biofilms; Drug Liberation; Fluoroquinolones; Rifampin; Triclosan; Urinary Catheters

2015